Page last updated: 2024-08-22

phenacid and chlorambucil

phenacid has been researched along with chlorambucil in 13 studies

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19907 (53.85)18.7374
1990's3 (23.08)18.2507
2000's3 (23.08)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hansch, C; Leo, A; Panthananickal, A1
Arsenou, ES; Fousteris, MA; Koutsourea, AI; Nikolaropoulos, SS; Pairas, GN; Papageorgiou, A1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
Farmer, PB; Foster, AB; Jarman, M; Kiburis, JH; Newell, DR; Oddy, MR1
Egge, H; Lathan, B; Malek, M; Musch, E; Peter-Katalinic, J; Riedel, E; Rink, H1
Genka, S; Greig, NH; John, V; Rapoport, SI; Shetty, HU; Soncrant, TT; Stahle, PL1
Lohmar, F; Mühlenbruch, BJ; Musch, E; Von Unruh, GE1
Loos, U; Malek, M; Mühlenbruch, B; Musch, E; Oppitz, MM; Rüb, HP; von Unruh, GE1
Ehrsson, H; Hartvig, P; Oberg, G; Simonsson, B; Wallin, I2
Coe, P; Lee, FY; Workman, P1
Ali-Osman, F; Deutsch, J; Genka, S; Greig, NH; John, V; Lieberburg, IM; Rapoport, SI; Shetty, UH; Stahle, PL1
Hovinen, J; Salmelin, C; Vilpo, J1

Trials

1 trial(s) available for phenacid and chlorambucil

ArticleYear
Inter- and intraindividual differences in oral chlorambucil pharmacokinetics.
    European journal of clinical pharmacology, 1988, Volume: 35, Issue:5

    Topics: Administration, Oral; Aged; Chlorambucil; Clinical Trials as Topic; Female; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Male; Middle Aged; Nitrogen Mustard Compounds; Random Allocation

1988

Other Studies

12 other study(ies) available for phenacid and chlorambucil

ArticleYear
Structure-activity relationships in antitumor aniline mustards.
    Journal of medicinal chemistry, 1978, Volume: 21, Issue:1

    Topics: Aniline Mustard; Animals; Antineoplastic Agents; Carcinoma 256, Walker; Hydrolysis; Lethal Dose 50; Leukemia L1210; Leukemia, Experimental; Mice; Models, Biological; Nitrogen Mustard Compounds; Rats; Structure-Activity Relationship

1978
Rational design, synthesis, and in vivo evaluation of the antileukemic activity of six new alkylating steroidal esters.
    Bioorganic & medicinal chemistry, 2008, May-01, Volume: 16, Issue:9

    Topics: Alkylation; Animals; Antineoplastic Agents; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Design; Drug Screening Assays, Antitumor; Esters; Female; Injections, Intraperitoneal; Leukemia L1210; Leukemia P388; Male; Mice; Mice, Inbred BALB C; Mice, Inbred DBA; Molecular Structure; Neoplasm Transplantation; Neoplasms, Experimental; Stereoisomerism; Steroids; Structure-Activity Relationship

2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
The metabolism of deuterated analogues of chlorambucil by the rat.
    Chemico-biological interactions, 1979, Volume: 28, Issue:2-3

    Topics: Animals; Carcinoma; Chlorambucil; Chromatography, High Pressure Liquid; Deuterium; Female; Nitrogen Mustard Compounds; Phenylacetates; Rats

1979
Cellular kinetics of prednimustine versus chlorambucil plus prednisolone in vitro.
    Cancer chemotherapy and pharmacology, 1992, Volume: 29, Issue:4

    Topics: Animals; Carcinoma; Chlorambucil; Chromatography, High Pressure Liquid; Colonic Neoplasms; Mammary Neoplasms, Experimental; Melanoma, Experimental; Nitrogen Mustard Compounds; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednimustine; Prednisolone; Rats; Time Factors; Tumor Cells, Cultured

1992
High-performance liquid chromatographic analysis of chlorambucil tert.-butyl ester and its active metabolites chlorambucil and phenylacetic mustard in plasma and tissue.
    Journal of chromatography, 1990, Dec-14, Volume: 534

    Topics: Animals; Brain; Chlorambucil; Chromatography, High Pressure Liquid; Female; Nitrogen Mustard Compounds; Rats; Rats, Inbred Strains; Regression Analysis

1990
Gas chromatographic assay for chlorambucil and phenylacetic mustard in plasma.
    Journal of chromatography, 1989, Oct-27, Volume: 495

    Topics: Chemical Phenomena; Chemistry; Chlorambucil; Chromatography, Gas; Humans; Mass Spectrometry; Nitrogen Mustard Compounds

1989
Studies on the pharmacokinetics of chlorambucil and prednimustine in patients using a new high-performance liquid chromatographic assay.
    Cancer chemotherapy and pharmacology, 1989, Volume: 23, Issue:4

    Topics: Chlorambucil; Chromatography, High Pressure Liquid; Drug Combinations; Humans; Nitrogen Mustard Compounds; Prednimustine; Prednisolone; Time Factors

1989
Pharmacokinetic basis for the comparative antitumour activity and toxicity of chlorambucil, phenylacetic acid mustard and beta, beta-difluorochlorambucil (CB 7103) in mice.
    Cancer chemotherapy and pharmacology, 1986, Volume: 17, Issue:1

    Topics: Animals; Antineoplastic Agents; Blood Proteins; Chlorambucil; Chromatography, High Pressure Liquid; Hydrolysis; Kinetics; Lethal Dose 50; Male; Mice; Mice, Inbred C3H; Nitrogen Mustard Compounds; Protein Binding; Sarcoma, Experimental

1986
Effect of food on pharmacokinetics of chlorambucil and its main metabolite, phenylacetic acid mustard.
    European journal of clinical pharmacology, 1984, Volume: 27, Issue:1

    Topics: Adult; Aged; Biotransformation; Chlorambucil; Eating; Female; Humans; Kinetics; Leukemia, Lymphoid; Male; Middle Aged; Nitrogen Mustard Compounds; Time Factors

1984
Development of lipophilic anticancer agents for the treatment of brain tumors by the esterification of water-soluble chlorambucil.
    Clinical & experimental metastasis, 1993, Volume: 11, Issue:2

    Topics: Alkylating Agents; Animals; Antineoplastic Agents; Blood-Brain Barrier; Brain; Brain Neoplasms; Chlorambucil; Drug Stability; Esters; Female; Injections, Intravenous; Nitrogen Mustard Compounds; Rats; Rats, Wistar; Solubility

1993
Polymyxin permeabilization as a tool to investigate cytotoxicity of therapeutic aromatic alkylators in DNA repair-deficient Escherichia coli strains.
    Mutation research, 2000, May-08, Volume: 467, Issue:2

    Topics: Alkylating Agents; Antineoplastic Agents; Cell Division; Cell Membrane Permeability; Chlorambucil; Culture Media; DNA Repair; Dose-Response Relationship, Drug; Drug Resistance, Microbial; Escherichia coli; Genotype; Methylnitronitrosoguanidine; Mutagenicity Tests; Nitrogen Mustard Compounds; Polymyxins; Sensitivity and Specificity; Ultraviolet Rays

2000