Page last updated: 2024-09-05

phelorphan and enkephalin, leucine

phelorphan has been researched along with enkephalin, leucine in 2 studies

Compound Research Comparison

Studies (phelorphan)	Trials (phelorphan)	Recent Studies (post-2010) (phelorphan)	Studies (enkephalin, leucine)	Trials (enkephalin, leucine)	Recent Studies (post-2010) (enkephalin, leucine)
5	0	0	11,524	80	754

Protein Interaction Comparison

Protein	Taxonomy	enkephalin, leucine (IC50)
Delta-type opioid receptor	Mus musculus (house mouse)	0.0142
Kappa-type opioid receptor	Mus musculus (house mouse)	0.0417
Mu-type opioid receptor	Homo sapiens (human)	9.5
Mu-type opioid receptor	Mus musculus (house mouse)	0.0308
Mu-type opioid receptor	Cavia porcellus (domestic guinea pig)	0.246

Research

Studies (2)

Timeframe	Studies, this research(%)	All Research%
pre-1990	2 (100.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Dzoljic, MR; Haffmans, J; van Amsterdam, JC; Walsum, MV	1
Blad, MW; Soudijn, W; Van Amsterdam, JG; Van Buuren, KJ	1

Other Studies

2 other study(ies) available for phelorphan and enkephalin, leucine

Article	Year
Phelorphan, an inhibitor of enzymes involved in the biodegradation of enkephalins, affected the withdrawal symptoms in chronic morphine-dependent rats. Neuroscience, 1987, Volume: 22, Issue:1 Topics: Aminopeptidases; Animals; Brain; CD13 Antigens; Dipeptides; Dipeptidyl-Peptidases and Tripeptidyl-Peptidases; Endopeptidases; Enkephalins; Male; Morphine Dependence; Naloxone; Neprilysin; Protease Inhibitors; Rats; Rats, Inbred Strains; Receptors, Opioid; Substance Withdrawal Syndrome; Thiorphan; Tiopronin	1987
Synthesis of enkephalinase B inhibitors, and their activity on isolated enkephalin-degrading enzymes. European journal of pharmacology, 1987, Mar-31, Volume: 135, Issue:3 Topics: Animals; Brain; Chelating Agents; Chemical Phenomena; Chemistry; Corpus Striatum; Dipeptides; Endopeptidases; Enkephalins; In Vitro Techniques; Male; Neprilysin; Protease Inhibitors; Rats; Rats, Inbred Strains	1987

Article

Year

Phelorphan, an inhibitor of enzymes involved in the biodegradation of enkephalins, affected the withdrawal symptoms in chronic morphine-dependent rats.

Neuroscience, 1987, Volume: 22, Issue:1

Topics: Aminopeptidases; Animals; Brain; CD13 Antigens; Dipeptides; Dipeptidyl-Peptidases and Tripeptidyl-Peptidases; Endopeptidases; Enkephalins; Male; Morphine Dependence; Naloxone; Neprilysin; Protease Inhibitors; Rats; Rats, Inbred Strains; Receptors, Opioid; Substance Withdrawal Syndrome; Thiorphan; Tiopronin

1987

Synthesis of enkephalinase B inhibitors, and their activity on isolated enkephalin-degrading enzymes.

European journal of pharmacology, 1987, Mar-31, Volume: 135, Issue:3

Topics: Animals; Brain; Chelating Agents; Chemical Phenomena; Chemistry; Corpus Striatum; Dipeptides; Endopeptidases; Enkephalins; In Vitro Techniques; Male; Neprilysin; Protease Inhibitors; Rats; Rats, Inbred Strains

1987