Page last updated: 2024-08-16

pf 5901 and masoprocol

pf 5901 has been researched along with masoprocol in 13 studies

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19902 (15.38)18.7374
1990's8 (61.54)18.2507
2000's2 (15.38)29.6817
2010's1 (7.69)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kreft, AF; Musser, JH1
Bruneau, P; Delvare, C; Edwards, MP; McMillan, RM1
Bell, RL; Brooks, DW; Carter, GW; Dyer, RD; Holms, JH; Kerdesky, FA; Moore, JL1
Campbell, HF; Chan, WK; Galemmo, RA; Huang, FC; Johnson, WH; Lee, TD; Lin, CJ; Magnien, E; Tan, J; Youssefyeh, RD1
Chakraborty, UR; Coutts, SM; Gordon, RJ; Khandwala, A; Musser, JH; Neiss, ES; Pruss, TP; Sciortino, S; Van Inwegen, R; Weinryb, I1
Carter, GW; Dyer, RD; Holms, JH; Mazdiyasni, H; Ratajczyk, JD; Summers, JB1
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
Austin, CP; Fidock, DA; Hayton, K; Huang, R; Inglese, J; Jiang, H; Johnson, RL; Su, XZ; Wellems, TE; Wichterman, J; Yuan, J1
Achenbach, J; Barzen, S; Brüggerhoff, A; Hofmann, B; Ihlefeld, K; Kretschmer, SB; Proschak, E; Rödl, CB; Stark, H; Steinhilber, D; Vogt, D1
Grisham, MB; Keenan, CM; Vaananen, PM; Wallace, JL1
Derian, CK; Lewis, DF1
Anderson, DC; Hughes, H; Mitchell, JR; Shappell, SB; Smith, CW; Taylor, AA1
Adrian, TE; Ding, XZ; El-Metwally, TH; Kuszynski, CA1

Reviews

1 review(s) available for pf 5901 and masoprocol

ArticleYear
5-lipoxygenase: properties, pharmacology, and the quinolinyl(bridged)aryl class of inhibitors.
    Journal of medicinal chemistry, 1992, Jul-10, Volume: 35, Issue:14

    Topics: Animals; Arachidonate 5-Lipoxygenase; Asthma; Eosinophils; Humans; Inflammation; Leukotriene Antagonists; Lipoxygenase Inhibitors; Lung Diseases; Neutrophils; Quinolines

1992

Other Studies

12 other study(ies) available for pf 5901 and masoprocol

ArticleYear
Indazolinones, a new series of redox-active 5-lipoxygenase inhibitors with built-in selectivity and oral activity.
    Journal of medicinal chemistry, 1991, Volume: 34, Issue:3

    Topics: Administration, Oral; Animals; Chemical Phenomena; Chemistry; Dinoprostone; Dogs; Humans; Indazoles; Leukotriene B4; Lipoxygenase Inhibitors; Male; Methemoglobinemia; Methylation; Molecular Structure; Oxidation-Reduction; Rats; Rats, Inbred Strains; Stereoisomerism; Structure-Activity Relationship; Thromboxane B2

1991
4-hydroxythiazole inhibitors of 5-lipoxygenase.
    Journal of medicinal chemistry, 1991, Volume: 34, Issue:7

    Topics: Animals; Arachidonate 5-Lipoxygenase; Chemical Phenomena; Chemistry; Enzyme Inhibitors; Humans; Lipoxygenase Inhibitors; Male; Rats; Rats, Inbred Strains; Structure-Activity Relationship; Thiazoles

1991
Development of a novel series of (2-quinolinylmethoxy)phenyl-containing compounds as high-affinity leukotriene receptor antagonists. 1. Initial structure-activity relationships.
    Journal of medicinal chemistry, 1990, Volume: 33, Issue:4

    Topics: Animals; Azoles; Bronchodilator Agents; Chemical Phenomena; Chemistry; Guinea Pigs; Hydroxyquinolines; Leukotriene Antagonists; Lung; Phenyl Ethers; Quinolines; Receptors, Immunologic; Receptors, Leukotriene B4; Structure-Activity Relationship; Tetrazoles

1990
Substituted arylmethyl phenyl ethers. 1. A novel series of 5-lipoxygenase inhibitors and leukotriene antagonists.
    Journal of medicinal chemistry, 1987, Volume: 30, Issue:1

    Topics: Animals; Arachidonate Lipoxygenases; Hydroxyeicosatetraenoic Acids; Indicators and Reagents; Lipoxygenase Inhibitors; Lung; Neutrophils; Phenyl Ethers; Rats; SRS-A; Structure-Activity Relationship

1987
Hydroxamic acid inhibitors of 5-lipoxygenase.
    Journal of medicinal chemistry, 1987, Volume: 30, Issue:3

    Topics: Arachidonate Lipoxygenases; Cell Line; Hydroxamic Acids; Kinetics; Lipoxygenase Inhibitors; Magnetic Resonance Spectroscopy; Molecular Conformation; Protein Binding; Structure-Activity Relationship

1987
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.
    Nature chemical biology, 2009, Volume: 5, Issue:10

    Topics: Animals; Antimalarials; ATP Binding Cassette Transporter, Subfamily B, Member 1; Chromosome Mapping; Crosses, Genetic; Dihydroergotamine; Drug Design; Drug Resistance; Humans; Inhibitory Concentration 50; Mutation; Plasmodium falciparum; Quantitative Trait Loci; Transfection

2009
Multi-dimensional target profiling of N,4-diaryl-1,3-thiazole-2-amines as potent inhibitors of eicosanoid metabolism.
    European journal of medicinal chemistry, 2014, Sep-12, Volume: 84

    Topics: 5-Lipoxygenase-Activating Proteins; Aminophenols; Cyclooxygenase 2; Dose-Response Relationship, Drug; Eicosanoids; Enzyme Inhibitors; HeLa Cells; Humans; Molecular Structure; Structure-Activity Relationship; Thiazoles; Tumor Cells, Cultured; U937 Cells

2014
Pharmacological investigation of the role of leukotrienes in the pathogenesis of experimental NSAID gastropathy.
    Inflammation, 1992, Volume: 16, Issue:3

    Topics: 5-Lipoxygenase-Activating Proteins; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Benzopyrans; Carrier Proteins; Free Radical Scavengers; Gastric Mucosa; Hydroxyurea; Indoles; Indomethacin; Leukotriene Antagonists; Leukotriene B4; Leukotrienes; Lipoxygenase Inhibitors; Male; Masoprocol; Membrane Proteins; Organic Chemicals; Permeability; Phenylcarbamates; Propionates; Quinolines; Rats; Rats, Inbred Strains; Receptors, Immunologic; Receptors, Leukotriene; Receptors, Leukotriene B4; Single-Blind Method; Stomach Ulcer; Sulfonamides; Tetrazoles; Tosyl Compounds

1992
Activation of 15-lipoxygenase by low density lipoprotein in vascular endothelial cells. Relationship to the oxidative modification of low density lipoprotein.
    Prostaglandins, leukotrienes, and essential fatty acids, 1992, Volume: 45, Issue:1

    Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; 5,8,11,14-Eicosatetraynoic Acid; Animals; Aorta; Arachidonate 15-Lipoxygenase; Benzyl Compounds; Cells, Cultured; Copper; Copper Sulfate; Endothelium, Vascular; Enzyme Activation; Hydroxamic Acids; Hydroxyeicosatetraenoic Acids; Indomethacin; Linoleic Acid; Linoleic Acids; Lipoproteins, LDL; Lipoxygenase Inhibitors; Masoprocol; Oxidation-Reduction; Quinolines; Swine; Umbilical Veins

1992
Comparison of antioxidant and nonantioxidant lipoxygenase inhibitors on neutrophil function. Implications for pathogenesis of myocardial reperfusion injury.
    The Journal of pharmacology and experimental therapeutics, 1990, Volume: 252, Issue:2

    Topics: Antigens, Differentiation; Antioxidants; Cell Aggregation; Cell Movement; Humans; Hydroxyquinolines; Imidazoles; Leukotriene B4; Lipoxygenase Inhibitors; Macrophage-1 Antigen; Masoprocol; Myocardial Reperfusion Injury; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Quinolines; Receptors, Leukocyte-Adhesion; Thiazoles

1990
Lipoxygenase inhibition induced apoptosis, morphological changes, and carbonic anhydrase expression in human pancreatic cancer cells.
    Biochemical and biophysical research communications, 1999, Dec-20, Volume: 266, Issue:2

    Topics: Apoptosis; Carbonic Anhydrases; Cell Differentiation; Cell Division; Cell Size; DNA Fragmentation; Flavanones; Flavonoids; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Humans; In Situ Nick-End Labeling; Lipoxygenase Inhibitors; Masoprocol; Pancreatic Neoplasms; Propidium; Quinolines; Tumor Cells, Cultured

1999