Page last updated: 2024-08-16

pf 5901 and ly 171883

pf 5901 has been researched along with ly 171883 in 11 studies

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19906 (54.55)18.7374
1990's2 (18.18)18.2507
2000's2 (18.18)29.6817
2010's1 (9.09)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kreft, AF; Musser, JH1
Chang, J; Kubrak, DM; Lewis, AJ; Musser, JH1
Bender, RH; Chang, J; Hand, JM; Kreft, AF; Kubrak, DM; Lefer, AM; Lewis, AJ; Musser, JH; Nielsen, ST1
Chang, J; DiZio, SM; Hand, JM; Hite, M; Kubrak, DM; Lewis, AJ; Musser, JH1
Brooks, CD; Summers, JB1
Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL1
Jolly, SR; Travis, J; Van Inwegen, RG1
Barnes, N; Costello, J; Evans, J; Piper, P; Zakrzewski, J1
Beninati, L; Chang, J; Nielsen, ST1
Huang, HT; Li, PC; Liang, JT; Lin, PH; Wu, SN1
Gao, C; Gao, N; Gao, X; Hu, HZ; Liu, S; Wang, G; Wang, X; Wood, JD; Xia, Y1

Reviews

3 review(s) available for pf 5901 and ly 171883

ArticleYear
5-lipoxygenase: properties, pharmacology, and the quinolinyl(bridged)aryl class of inhibitors.
    Journal of medicinal chemistry, 1992, Jul-10, Volume: 35, Issue:14

    Topics: Animals; Arachidonate 5-Lipoxygenase; Asthma; Eosinophils; Humans; Inflammation; Leukotriene Antagonists; Lipoxygenase Inhibitors; Lung Diseases; Neutrophils; Quinolines

1992
Modulators of leukotriene biosynthesis and receptor activation.
    Journal of medicinal chemistry, 1996, Jul-05, Volume: 39, Issue:14

    Topics: 5-Lipoxygenase-Activating Proteins; Animals; Carrier Proteins; Forecasting; Humans; Leukotriene B4; Leukotrienes; Lipoxygenase Inhibitors; Membrane Proteins; Molecular Structure; Receptors, Leukotriene

1996
Studies of leukotriene antagonists and synthesis inhibitors in man.
    Progress in clinical and biological research, 1988, Volume: 263

    Topics: Acetophenones; Asthma; Chromones; Epoprostenol; Humans; Hydroxyquinolines; Keto Acids; Leukotriene B4; Phenylbutyrates; Quinolines; SRS-A; Sulfones; Tetrazoles

1988

Other Studies

8 other study(ies) available for pf 5901 and ly 171883

ArticleYear
Synthesis of [[(naphthalenylmethoxy)- and [[(quinolinylmethoxy)phenyl]amino]oxoalkanoic acid esters. A novel series of leukotriene D4 antagonists and 5-lipoxygenase inhibitors.
    Journal of medicinal chemistry, 1986, Volume: 29, Issue:8

    Topics: Animals; Arachidonate Lipoxygenases; Bronchi; Guinea Pigs; Lipoxygenase Inhibitors; Male; Methyl Ethers; Muscle Contraction; Naphthalenes; Neutrophils; Ovalbumin; Quinolines; Rats; SRS-A; Structure-Activity Relationship; Trachea

1986
Phenylephrine derivatives as leukotriene D4 antagonists.
    Journal of medicinal chemistry, 1987, Volume: 30, Issue:11

    Topics: Animals; Bronchial Spasm; Cats; Coronary Circulation; Gastric Mucosa; Guinea Pigs; In Vitro Techniques; Lipoxygenase Inhibitors; Male; Phenylephrine; Rats; SRS-A; Trachea

1987
Leukotriene D4 antagonists and 5-lipoxygenase inhibitors. Synthesis of benzoheterocyclic [(methoxyphenyl)amino]oxoalkanoic acid esters.
    Journal of medicinal chemistry, 1987, Volume: 30, Issue:2

    Topics: Animals; Arachidonate 5-Lipoxygenase; Arachidonate Lipoxygenases; Fatty Acids; Guinea Pigs; Heterocyclic Compounds; Indicators and Reagents; Lipoxygenase Inhibitors; Magnetic Resonance Spectroscopy; Mass Spectrometry; Muscle Contraction; Muscle, Smooth; Neutrophils; Rats; Spectrophotometry, Infrared; SRS-A; Structure-Activity Relationship

1987
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
    PloS one, 2016, Volume: 11, Issue:10

    Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat

2016
Effects of 5-lipoxygenase inhibition on cardiac anaphylaxis in isolated guinea pig hearts.
    Pharmacology, 1989, Volume: 38, Issue:6

    Topics: Acetophenones; Anaphylaxis; Animals; Arachidonate Lipoxygenases; Benzoquinones; Benzyl Compounds; Blood Pressure; Cardiomyopathies; Chromones; Coronary Circulation; Guinea Pigs; Heart; Hydroxamic Acids; Hydroxyquinolines; In Vitro Techniques; Indomethacin; Lipoxygenase Inhibitors; Male; Myocardium; Quinolines; Quinones; SRS-A; Tetrazoles

1989
REV 5901 and Ly 171,883 protect rat gastric mucosa against ethanol-induced damage.
    Agents and actions, 1987, Volume: 21, Issue:3-4

    Topics: Acetophenones; Animals; Azoles; Ethanol; Gastric Mucosa; Hydroxyquinolines; Lipoxygenase Inhibitors; Male; Quinolines; Rats; Rats, Inbred Strains; SRS-A; Tetrazoles

1987
Enhanced activity of Ca2+-activated K+ channels by 1-[2-hydroxy-3-propyl-4-[(1H-tetrazol-5-yl)butoxyl]phenyl] ethanone (LY-171883) in neuroendocrine and neuroblastoma cell lines.
    Journal of cellular physiology, 2002, Volume: 192, Issue:2

    Topics: Acetophenones; Action Potentials; Animals; Cell Membrane; Electrophysiology; Humans; Large-Conductance Calcium-Activated Potassium Channels; Leukotriene Antagonists; Leukotriene D4; Membrane Potentials; Neuroblastoma; Patch-Clamp Techniques; Pituitary Neoplasms; Potassium Channels, Calcium-Activated; Propionates; Quinolines; Rats; Tetrazoles; Trypsin; Tumor Cells, Cultured

2002
Actions of cysteinyl leukotrienes in the enteric nervous system of guinea-pig stomach and small intestine.
    European journal of pharmacology, 2003, Jan-10, Volume: 459, Issue:1

    Topics: Acetophenones; Animals; Cysteine; Enteric Nervous System; Guinea Pigs; In Vitro Techniques; Intestine, Small; Leukotriene Antagonists; Leukotrienes; Male; Membrane Potentials; Neurons; Propionates; Quinolines; SRS-A; Stomach; Synaptic Transmission; Tetrazoles

2003