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pf 5901 and leukotriene b4

pf 5901 has been researched along with leukotriene b4 in 11 studies

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19903 (27.27)18.7374
1990's7 (63.64)18.2507
2000's1 (9.09)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Gale, D; Keenan, CM; Shoupe, TS; Wallace, JL1
Grisham, MB; Keenan, CM; Vaananen, PM; Wallace, JL1
McCafferty, DM; Rioux, KJ; Wallace, JL1
Anderson, DC; Hughes, H; Mitchell, JR; Shappell, SB; Smith, CW; Taylor, AA1
Hatala, MA; Kraemer, R; Mullane, K; Sessa, W; Westlin, W1
Aharony, D; Krell, RD; Kusner, EJ; Marks, RL1
Barnes, N; Costello, J; Evans, J; Piper, P; Zakrzewski, J1
Clear, RM; Coggeshall, CW; Doyle, MJ; Eichhold, TH; Hynd, BA; Kuhlenbeck, DL; Wehmeyer, KR; Weisman, SM1
Burroughs, DA; Donigi-Gale, D; Herd, CM; Page, CP; Shoupe, TS; Yeadon, M1
Jones, CJ; MacIntyre, DE; McMillan, RM; Rossi, AG1
Lotan, R; Newman, RA; Schroeder, CP; Yang, P1

Reviews

1 review(s) available for pf 5901 and leukotriene b4

ArticleYear
Studies of leukotriene antagonists and synthesis inhibitors in man.
    Progress in clinical and biological research, 1988, Volume: 263

    Topics: Acetophenones; Asthma; Chromones; Epoprostenol; Humans; Hydroxyquinolines; Keto Acids; Leukotriene B4; Phenylbutyrates; Quinolines; SRS-A; Sulfones; Tetrazoles

1988

Other Studies

10 other study(ies) available for pf 5901 and leukotriene b4

ArticleYear
Exacerbation of experimental colitis by nonsteroidal anti-inflammatory drugs is not related to elevated leukotriene B4 synthesis.
    Gastroenterology, 1992, Volume: 102, Issue:1

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Colitis; Colon; Dinoprostone; Drug Combinations; Indomethacin; Leukotriene B4; Male; Misoprostol; Naproxen; Peroxidase; Quinolines; Rats; Rats, Inbred Strains

1992
Pharmacological investigation of the role of leukotrienes in the pathogenesis of experimental NSAID gastropathy.
    Inflammation, 1992, Volume: 16, Issue:3

    Topics: 5-Lipoxygenase-Activating Proteins; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Benzopyrans; Carrier Proteins; Free Radical Scavengers; Gastric Mucosa; Hydroxyurea; Indoles; Indomethacin; Leukotriene Antagonists; Leukotriene B4; Leukotrienes; Lipoxygenase Inhibitors; Male; Masoprocol; Membrane Proteins; Organic Chemicals; Permeability; Phenylcarbamates; Propionates; Quinolines; Rats; Rats, Inbred Strains; Receptors, Immunologic; Receptors, Leukotriene; Receptors, Leukotriene B4; Single-Blind Method; Stomach Ulcer; Sulfonamides; Tetrazoles; Tosyl Compounds

1992
Granulocyte infiltration in experimental colitis in the rat is interleukin-1 dependent and leukotriene independent.
    Eicosanoids, 1992, Volume: 5, Issue:3-4

    Topics: Analysis of Variance; Animals; Benzopyrans; Chemotaxis, Leukocyte; Colitis; Interleukin-1; Kinetics; Leukotriene B4; Male; Neutrophils; Peroxidase; Quinolines; Rats; Rats, Wistar; Trinitrobenzenesulfonic Acid

1992
Comparison of antioxidant and nonantioxidant lipoxygenase inhibitors on neutrophil function. Implications for pathogenesis of myocardial reperfusion injury.
    The Journal of pharmacology and experimental therapeutics, 1990, Volume: 252, Issue:2

    Topics: Antigens, Differentiation; Antioxidants; Cell Aggregation; Cell Movement; Humans; Hydroxyquinolines; Imidazoles; Leukotriene B4; Lipoxygenase Inhibitors; Macrophage-1 Antigen; Masoprocol; Myocardial Reperfusion Injury; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Quinolines; Receptors, Leukocyte-Adhesion; Thiazoles

1990
Myocardial salvage induced by REV-5901: an inhibitor and antagonist of the leukotrienes.
    Journal of cardiovascular pharmacology, 1987, Volume: 10, Issue:4

    Topics: Animals; Arachidonate Lipoxygenases; Dogs; Hydroxyquinolines; Leukotriene B4; Lipoxygenase Inhibitors; Male; Myocardial Infarction; Neutrophils; Quinolines; Rabbits; SRS-A

1987
Inhibition by REV-5901 of leukotriene release from guinea-pig and human lung tissue in vitro.
    Biochemical pharmacology, 1989, Dec-01, Volume: 38, Issue:23

    Topics: Animals; Calcimycin; Culture Techniques; Drug Interactions; Guinea Pigs; Histamine; Humans; Hydroxyquinolines; Leukotriene B4; Lipoxygenase Inhibitors; Lung; Male; Prostaglandin-Endoperoxide Synthases; Quinolines; SRS-A; Thromboxane B2; Time Factors

1989
Effects of tebufelone (NE-11740), a new anti-inflammatory drug, on arachidonic acid metabolism.
    Agents and actions, 1994, Volume: 41, Issue:3-4

    Topics: Alkynes; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Calcimycin; Cyclooxygenase Inhibitors; Dinoprostone; Humans; Indomethacin; Leukotriene B4; Lipoxygenase Inhibitors; Macrophages, Peritoneal; Male; Phenols; Prostaglandin-Endoperoxide Synthases; Quinolines; Rats

1994
Effect of a 5-lipoxygenase inhibitor and leukotriene antagonist (PF 5901) on antigen-induced airway responses in neonatally immunized rabbits.
    British journal of pharmacology, 1994, Volume: 112, Issue:1

    Topics: Administration, Inhalation; Airway Resistance; Alternaria; Animals; Animals, Newborn; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Bronchoconstriction; Female; Histamine; Leukotriene B4; Leukotriene D4; Lipoxygenase Inhibitors; Lung; Lung Compliance; Male; Quinolines; Rabbits; Respiratory Function Tests; Respiratory Hypersensitivity

1994
Stimulation of human polymorphonuclear leukocytes by leukotriene B4 and platelet-activating factor: an ultrastructural and pharmacological study.
    Journal of leukocyte biology, 1993, Volume: 53, Issue:2

    Topics: Acetylglucosaminidase; Adult; Cell Aggregation; Dose-Response Relationship, Drug; Humans; In Vitro Techniques; Ionomycin; Leukotriene B4; Lipoxygenase Inhibitors; Microscopy, Electron; Muramidase; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Quinolines

1993
Simultaneous inhibition of COX-2 and 5-LOX activities augments growth arrest and death of premalignant and malignant human lung cell lines.
    Journal of experimental therapeutics & oncology, 2007, Volume: 6, Issue:3

    Topics: 5-Lipoxygenase-Activating Proteins; Apoptosis; Blotting, Western; Carrier Proteins; Celecoxib; Cell Cycle; Cell Death; Cell Division; Cell Line, Tumor; Cyclooxygenase 2 Inhibitors; Dinoprostone; Humans; Hydroxyeicosatetraenoic Acids; Indoles; Leukotriene B4; Lipoxygenase Inhibitors; Lung Neoplasms; Membrane Proteins; Pyrazoles; Quinolines; Spectrometry, Mass, Electrospray Ionization; Sulfonamides

2007