perphenazine has been researched along with nortriptyline in 50 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 28 (56.00) | 18.7374 |
1990's | 4 (8.00) | 18.2507 |
2000's | 11 (22.00) | 29.6817 |
2010's | 6 (12.00) | 24.3611 |
2020's | 1 (2.00) | 2.80 |
Authors | Studies |
---|---|
Chiang, GH; Unger, SH | 1 |
Topliss, JG; Yoshida, F | 1 |
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY | 1 |
Johans, C; Kinnunen, PK; Söderlund, T; Suomalainen, P | 1 |
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
Lombardo, F; Obach, RS; Waters, NJ | 1 |
Ahman, M; Holmén, AG; Wan, H | 1 |
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM | 1 |
García-Mera, X; González-Díaz, H; Prado-Prado, FJ | 1 |
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ | 1 |
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
Albert, JM; Cooper, SF; Dugal, R; Elie, R | 1 |
Gram, LF; Hansen, V; Overo, KF | 1 |
Albert, JM; Bertrand, M; Cooper, S; Dugal, R; Elie, R | 1 |
Bolvig Hansen, L; Borgå, O; Garle, M; Hansen, CE; Hvidberg, EF; Kragh-Sorensen, P; Larsen, NE; Sjöqvist, F | 1 |
Henry, BW; Overall, JE; Woodward, JA | 1 |
Larsen, NE; Naestoft, J | 1 |
Dealy, RS; Griffin, SJ; Hanin, I; Perel, JM; Soloff, PH; Spiker, DG; Weiss, JC | 1 |
Frisk-Holmberg, M; van der Kleijn, E | 1 |
Taub, A | 1 |
De Leenheer, A; Heyndrickx, A | 1 |
Chopra, YM; Dandiya, PC | 1 |
Christiansen, J; Gram, LF; Overo, KF | 2 |
Dandiya, PC; Patni, SK | 1 |
Anderson, J; Lambert, NG; Pigott, PV | 1 |
Pigott, PV | 1 |
Gram, LF; Kirk, L; Overo, K | 1 |
Kanzler, M; Malitz, S | 1 |
Gram, LF; Overo, KF | 1 |
Gram, LF | 1 |
Oates, JA; Shand, DG | 1 |
Núnek, K | 1 |
Horioka, T; Kaneko, H; Masuda, Y; Murai, K; Nakamura, H | 1 |
Ashford, A; Ross, JW | 1 |
Hollister, LE; Kimbell, I; Overall, JE; Shelton, J | 1 |
Kragh-Sørensen, P | 1 |
George, L; Guthrie, S; Linnoila, M | 1 |
Begley, A; Cornes, C; Dew, MA; Frank, E; Hall, M; Houck, PR; Kupfer, DJ; Mazumdar, S; Miller, MD; Mulsant, B; Perel, JM; Reynolds, CF; Shear, MK | 1 |
De Meester, I; Desnyder, R; Maes, M; Meltzer, HY; Ranjan, R; Scharpe, S | 1 |
Foglia, JP; Lo, KH; Mulsant, BH; Pollock, BG; Rosen, J; Sweet, RA | 1 |
Flint, AJ; Rifat, SL | 1 |
Begley, AE; Flynn, T; Mazumdar, S; Mulsant, BH; Pollock, BG; Reynolds, CF; Rosen, J; Sweet, RA; Zubenko, GS | 1 |
Alexopoulos, GS; Gabriele, M; Hamilton, M; Kakuma, T; Klimstra, SA; Meyers, BS; Tirumalasetti, F | 1 |
Bowser, MT; Carr, PW; Dai, J; Lucy, CA; Mendonsa, SD | 1 |
Gowda, R; Kuzu, OF; Noory, MA; Robertson, GP | 1 |
Abdelhamid, NS; Anwar, BH; Farid, NF; Magdy, MA | 1 |
2 review(s) available for perphenazine and nortriptyline
Article | Year |
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DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
The use of clinical kinetic data in treatment with antidepressant drugs.
Topics: Adult; Affective Symptoms; Aged; Drug Therapy, Combination; Female; Humans; Imipramine; Kinetics; Male; Middle Aged; Nortriptyline; Perphenazine | 1980 |
9 trial(s) available for perphenazine and nortriptyline
Article | Year |
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The pharmacological treatment of delusional depression: Part II.
Topics: Amitriptyline; Delusions; Depressive Disorder; Double-Blind Method; Drug Therapy, Combination; Humans; Nortriptyline; Perphenazine; Psychiatric Status Rating Scales; Random Allocation | 1986 |
An evaluation of fluphenazine with nortriptyline in anxiety and depression.
Topics: Amitriptyline; Anxiety; Clinical Trials as Topic; Depression; Drug Combinations; Fluphenazine; Humans; Nortriptyline; Perphenazine; Placebos | 1972 |
A review of clinical studies with combinations of fluphenazine and nortriptyline.
Topics: Amitriptyline; Anxiety; Central Nervous System; Clinical Trials as Topic; Depression; Diazepam; Doxepin; Drug Combinations; Fluphenazine; Heart Conduction System; Humans; Motor Activity; Nortriptyline; Perphenazine; Placebos; Psychiatric Status Rating Scales; Vision Disorders | 1972 |
Are antidepressants better than placebo?
Topics: Adjustment Disorders; Adult; Aged; Amitriptyline; Antidepressive Agents; Anxiety; Clinical Trials as Topic; Depression; Dextroamphetamine; Diazepam; Dibenzocycloheptenes; Fatigue; Female; Humans; Male; Middle Aged; Nortriptyline; Perphenazine; Phenytoin; Placebos; Propylamines; Sleep; Xerostomia | 1971 |
High relapse rate after discontinuation of adjunctive medication for elderly patients with recurrent major depression.
Topics: Age Factors; Age of Onset; Aged; Antidepressive Agents; Combined Modality Therapy; Depressive Disorder; Double-Blind Method; Drug Therapy, Combination; Female; Hospitalization; Humans; Lithium; Male; Nortriptyline; Paroxetine; Perphenazine; Placebos; Psychotherapy; Recurrence; Risk Factors; Treatment Outcome | 1996 |
The effects of perphenazine on the concentration of nortriptyline and its hydroxymetabolites in older patients.
Topics: Aged; Antidepressive Agents, Tricyclic; Antipsychotic Agents; Depressive Disorder; Drug Interactions; Female; Humans; Hydroxylation; Male; Nortriptyline; Perphenazine | 1997 |
The treatment of psychotic depression in later life: a comparison of pharmacotherapy and ECT.
Topics: Age Distribution; Aged; Aged, 80 and over; Antidepressive Agents, Tricyclic; Antipsychotic Agents; Depressive Disorder; Drug Therapy, Combination; Electroconvulsive Therapy; Female; Humans; Lithium; Male; Nortriptyline; Perphenazine; Psychotic Disorders; Treatment Outcome | 1998 |
A double-blind randomized comparison of nortriptyline plus perphenazine versus nortriptyline plus placebo in the treatment of psychotic depression in late life.
Topics: Affective Disorders, Psychotic; Age Factors; Aged; Antidepressive Agents, Tricyclic; Antipsychotic Agents; Depressive Disorder; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Female; Hospitalization; Humans; Male; Nortriptyline; Perphenazine; Placebos; Psychiatric Status Rating Scales; Treatment Outcome | 2001 |
Continuation treatment of delusional depression in older adults.
Topics: Aged; Antidepressive Agents, Tricyclic; Antipsychotic Agents; Combined Modality Therapy; Delusions; Depression; Double-Blind Method; Drug Therapy, Combination; Electroconvulsive Therapy; Female; Humans; Male; Middle Aged; Nortriptyline; Perphenazine; Treatment Outcome | 2001 |
39 other study(ies) available for perphenazine and nortriptyline
Article | Year |
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Octanol-physiological buffer distribution coefficients of lipophilic amines by reversed-phase high-performance liquid chromatography and their correlation with biological activity.
Topics: Amines; Animals; Buffers; Chromatography, High Pressure Liquid; Histamine Release; Lipid Metabolism; Octanols; Protein Binding; Rats; Serum Albumin, Bovine; Sodium-Potassium-Exchanging ATPase; Solubility; Structure-Activity Relationship | 1981 |
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution | 2004 |
Surface activity profiling of drugs applied to the prediction of blood-brain barrier permeability.
Topics: Blood-Brain Barrier; Lipid Bilayers; Micelles; Permeability; Pharmaceutical Preparations; Structure-Activity Relationship; Surface Properties | 2004 |
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Relationship between brain tissue partitioning and microemulsion retention factors of CNS drugs.
Topics: Brain; Central Nervous System; Chromatography, Liquid; Emulsions; Mass Spectrometry | 2009 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
Topics: | 2008 |
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics | 2010 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics | 2010 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Metabolic interaction between amitriptyline and perphenazine in psychiatric patients.
Topics: Adult; Amitriptyline; Drug Interactions; Female; Humans; Male; Middle Aged; Nortriptyline; Perphenazine; Random Allocation; Schizophrenia | 1979 |
Interaction of perphenazine with the kinetics of nortriptyline.
Topics: Dose-Response Relationship, Drug; Drug Interactions; Half-Life; Humans; Injections, Intravenous; Nortriptyline; Perphenazine | 1977 |
Gas chromatographic determination of amitriptyline, nortriptyline and perphenazine in plasma of schizophrenic patients after administration of the combination of amitriptyline with perphenazine.
Topics: Adult; Amitriptyline; Chromatography, Gas; Drug Combinations; Female; Humans; Male; Middle Aged; Nortriptyline; Perphenazine; Schizophrenia | 1979 |
Effect of simultaneous treatment with low doses of perphenazine on plasma and urine concentrations of nortriptyline and 10-hydroxynortriptyline.
Topics: Adult; Drug Interactions; Female; Humans; Hydroxylation; Male; Middle Aged; Nortriptyline; Perphenazine; Time Factors | 1977 |
Patterns of symptom change in anxious depressed outpatients treated with different drugs.
Topics: Amitriptyline; Antidepressive Agents; Anxiety; Chlordiazepoxide; Chlorpromazine; Depression; Desipramine; Diazepam; Drug Combinations; Fluphenazine; Humans; Imipramine; Mental Disorders; Nortriptyline; Perphenazine; Thioridazine; Thiothixene; Tranquilizing Agents; Trifluoperazine | 1975 |
Determination of perphenazine and its sulphoxide metabolite in human plasma after therapeutic doses by gas chromatography.
Topics: Biotransformation; Chromatography, Gas; Humans; Injections, Intramuscular; Methods; Nortriptyline; Perphenazine; Piperidines; Sulfoxides; Time Factors | 1975 |
The relationship between the lipophilic nature of tricyclic neuroleptics and antidepressants, and histamine release.
Topics: Amitriptyline; Animals; Antidepressive Agents; Cell Membrane Permeability; Chemical Phenomena; Chemistry; Chlorpromazine; Chlorprothixene; Clopenthixol; Desipramine; Fluphenazine; Histamine Release; Imipramine; Kinetics; Male; Mast Cells; Methotrimeprazine; Nortriptyline; Perphenazine; Phenothiazines; Prochlorperazine; Promazine; Promethazine; Rats; Solvents; Structure-Activity Relationship; Thioridazine; Tranquilizing Agents; Trifluoperazine | 1972 |
Relief of postherpetic neuralgia with psychotropic drugs.
Topics: Aged; Amitriptyline; Analgesics; Antidepressive Agents; Antipsychotic Agents; Female; Fluphenazine; Herpesviridae Infections; Humans; Male; Middle Aged; Neuralgia; Nortriptyline; Pain; Perphenazine; Thioridazine | 1973 |
Identification of phenothiazine derivatives and analogs by x-ray diffraction. II. Active substances in pharmaceutical formulations.
Topics: Amitriptyline; Chlorprothixene; Crystallization; Dibenzazepines; Fluphenazine; Imipramine; Methods; Methotrimeprazine; Nortriptyline; Opipramol; Perphenazine; Phenothiazines; Picrates; Prochlorperazine; Promazine; Promethazine; Quaternary Ammonium Compounds; Thioridazine; Triflupromazine; X-Ray Diffraction | 1971 |
The mechanism of the potentiating effect of antidepressant drugs on the protective influenc oe of diphenhydramine in experimental catatonia. The role of histamine.
Topics: Animals; Antidepressive Agents; Brain; Brain Chemistry; Catatonia; Diphenhydramine; Drug Synergism; Histamine; Humans; Male; Monoamine Oxidase Inhibitors; Nortriptyline; Perphenazine; Phenelzine; Rats; Time Factors; Tryptamines | 1974 |
Pharmacokinetic interaction between neuroleptics and tricyclic antidepressants in the rat.
Topics: Animals; Brain; Carbon Radioisotopes; Chlorpromazine; Chromatography, Thin Layer; Desipramine; Dose-Response Relationship, Drug; Drug Interactions; Erythrocytes; Feces; Glucuronates; Heart; Imipramine; Injections, Intraperitoneal; Male; Nortriptyline; Perphenazine; Rats | 1974 |
The influence of monoamine oxidase inhibitors and some other antidepressants on the anti-parkinsonian activity of sub-effective doses of diphenylhydramine in rats and mice.
Topics: Animals; Antidepressive Agents; Catatonia; Diphenhydramine; Humans; Mice; Monoamine Oxidase Inhibitors; Nortriptyline; Parasympatholytics; Parkinson Disease; Parkinson Disease, Secondary; Perphenazine; Phenelzine; Rats; Tremorine | 1972 |
[Pharmacokinetic interaction between neuroleptics and antidepressive agents: organ reactions and models of metabolism].
Topics: Animals; Carbon Isotopes; Drug Interactions; Imipramine; Nortriptyline; Perphenazine; Rats | 1972 |
Influence of neuroleptics and benzodiazepines on metabolism of tricyclic antidepressants in man.
Topics: Animals; Antidepressive Agents; Carbon Radioisotopes; Chlordiazepoxide; Diazepam; Dose-Response Relationship, Drug; Drug Interactions; Female; Haloperidol; Humans; Middle Aged; Nortriptyline; Perphenazine; Rats; Schizophrenia; Tranquilizing Agents | 1974 |
Drug interaction: inhibitory effect of neuroleptics on metabolism of tricyclic antidepressants in man.
Topics: Adult; Carbon Isotopes; Chlorpromazine; Drug Interactions; Ethanol; Female; Haloperidol; Humans; Imipramine; Male; Middle Aged; Nortriptyline; Perphenazine; Piperazines; Tranquilizing Agents | 1972 |
[Drug interactions: blocking effect of neuroleptics on the metabolism of tricyclic antidepressive agents].
Topics: Carbon Isotopes; Drug Interactions; Humans; Imipramine; Nortriptyline; Perphenazine; Tranquilizing Agents | 1971 |
Metabolism of propranolol by rat liver microsomes and its inhibition by phenothiazine and tricyclic antidepressant drugs.
Topics: Amitriptyline; Animals; Antidepressive Agents; Chlorpromazine; Desipramine; Imipramine; Kinetics; Liver; Male; Metabolism; Microsomes, Liver; NAD; NADP; Nitrogen; Nortriptyline; Perphenazine; Phenothiazines; Prochlorperazine; Promazine; Promethazine; Propranolol; Rats; Subcellular Fractions; Trifluoperazine; Triflupromazine | 1971 |
[Current problems of endogenous depression].
Topics: Amitriptyline; Antidepressive Agents; Chlorpromazine; Convulsive Therapy; Depression; Desipramine; Fluphenazine; Humans; Imipramine; Methotrimeprazine; Nortriptyline; Perphenazine; Thioridazine | 1970 |
[Pharmacological studies of a new antidepressant nortriptyline (Noritren)].
Topics: Amitriptyline; Animals; Behavior, Animal; Body Temperature; Brain Chemistry; Cats; Chlorpromazine; Conditioning, Classical; Electroencephalography; Haloperidol; Imipramine; Mice; Norepinephrine; Nortriptyline; Perphenazine; Rats; Reserpine; Serotonin; Sleep | 1970 |
Toxicity of depressant and antidepressant drugs in hyperthyroid mice.
Topics: Animals; Antidepressive Agents; Chlordiazepoxide; Chlorpromazine; Female; Hyperthyroidism; Imipramine; Meprobamate; Mice; Nortriptyline; Oxygen Consumption; Perphenazine; Phenothiazines; Reserpine; Sympathomimetics; Tranquilizing Agents | 1968 |
Extrinsic factors influencing responses to psychotherapeutic drugs.
Topics: Adult; Amitriptyline; Analysis of Variance; Black or African American; Chlorpromazine; Depression; Diazepam; Hospitalization; Humans; Nortriptyline; Perphenazine; Phenothiazines; Prognosis; Psychiatric Status Rating Scales; Schizophrenia; Socioeconomic Factors; Sulfonamides | 1969 |
Interaction between antidepressants and perphenazine in psychiatric inpatients.
Topics: Adult; Amitriptyline; Depressive Disorder; Dose-Response Relationship, Drug; Drug Interactions; Drug Therapy, Combination; Dyskinesia, Drug-Induced; Female; Hospitalization; Humans; Male; Nortriptyline; Perphenazine; Stimulation, Chemical | 1982 |
Alterations in plasma dipeptidyl peptidase IV enzyme activity in depression and schizophrenia: effects of antidepressants and antipsychotic drugs.
Topics: Adult; Antidepressive Agents; Antipsychotic Agents; Bipolar Disorder; Depressive Disorder; Dipeptidyl Peptidase 4; Dose-Response Relationship, Drug; Female; Fluoxetine; Haloperidol; Humans; Hydrocortisone; Imipramine; Male; Middle Aged; Nortriptyline; Perphenazine; Psychiatric Status Rating Scales; Schizophrenia; Schizophrenic Psychology | 1996 |
Effect of anionic additive type on ion pair formation constants of basic pharmaceuticals.
Topics: Amitriptyline; Anions; Chlorides; Electrophoresis, Capillary; Formates; Mathematics; Nortriptyline; Osmolar Concentration; Perchlorates; Perphenazine; Pharmaceutical Preparations; Trifluoroacetic Acid | 2005 |
Modulating cancer cell survival by targeting intracellular cholesterol transport.
Topics: Administration, Intravenous; Administration, Oral; Animals; Antidepressive Agents, Tricyclic; Antipsychotic Agents; Autophagy; bcl-2-Associated X Protein; Biological Transport; Cell Survival; Cholesterol; Desipramine; Endocytosis; Endosomes; Female; Flupenthixol; Fluphenazine; Gene Expression Regulation; Gene Knockdown Techniques; HCT116 Cells; Homeostasis; Humans; Inhibitory Concentration 50; Liposomes; Lysosomes; MCF-7 Cells; Melanoma; Mice; Nortriptyline; Perphenazine; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Signal Transduction; Sphingomyelin Phosphodiesterase; STAT3 Transcription Factor | 2017 |
Simultaneous spectrophotometric determination of fluphenazine HCl and nortriptyline HCl in presence of their potential impurities perphenazine and dibenzosuberone in bulk and pharmaceutical formulation.
Topics: Dibenzocycloheptenes; Drug Compounding; Fluphenazine; Nortriptyline; Perphenazine; Spectrophotometry | 2022 |