perphenazine has been researched along with doxepin in 20 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (30.00) | 18.7374 |
| 1990's | 3 (15.00) | 18.2507 |
| 2000's | 6 (30.00) | 29.6817 |
| 2010's | 5 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chiang, GH; Unger, SH | 1 |
| Topliss, JG; Yoshida, F | 1 |
| Johans, C; Kinnunen, PK; Söderlund, T; Suomalainen, P | 1 |
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Ahman, M; Holmén, AG; Wan, H | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Balogh, I; Kim, HY; Koczok, K; Korade, Z; Liu, W; Mirnics, K; Porter, NA; Tallman, KA; Xu, L | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Ketai, R | 1 |
| Pigott, PV | 1 |
| Downing, RW | 1 |
| Brown, AS; Csanalosi, I; Rickels, K; Von Poelnitz, M; Weinstock, R; Weise, CC; Werblowsky, J; Winokur, A | 1 |
| Dilsaver, SC; Domino, L | 1 |
| Huang, Z; Liu, W; Wu, H; Zhuo, X | 1 |
| Chen, C; Guo, S; Xue, G | 1 |
| Guan, FY; Luo, Y; Wu, HF | 1 |
1 review(s) available for perphenazine and doxepin
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
3 trial(s) available for perphenazine and doxepin
| Article | Year |
|---|---|
A review of clinical studies with combinations of fluphenazine and nortriptyline.
Topics: Amitriptyline; Anxiety; Central Nervous System; Clinical Trials as Topic; Depression; Diazepam; Doxepin; Drug Combinations; Fluphenazine; Heart Conduction System; Humans; Motor Activity; Nortriptyline; Perphenazine; Placebos; Psychiatric Status Rating Scales; Vision Disorders | 1972 |
Amitriptyline-perphenazine and doxepin in depressed outpatients: a controlled double-blind study.
Topics: Adult; Ambulatory Care; Amitriptyline; Clinical Trials as Topic; Depressive Disorder; Double-Blind Method; Doxepin; Drug Combinations; Female; Humans; Male; Perphenazine; Sleep Stages; Xerostomia | 1982 |
[Variation of female migraine after menopause and its prophylaxis and treatment].
Topics: Analgesics; Anti-Anxiety Agents; Antipsychotic Agents; Case-Control Studies; Doxepin; Estradiol Congeners; Female; Follow-Up Studies; Humans; Migraine Disorders; ortho-Aminobenzoates; Perphenazine; Postmenopause; Quinestrol | 1997 |
16 other study(ies) available for perphenazine and doxepin
| Article | Year |
|---|---|
Octanol-physiological buffer distribution coefficients of lipophilic amines by reversed-phase high-performance liquid chromatography and their correlation with biological activity.
Topics: Amines; Animals; Buffers; Chromatography, High Pressure Liquid; Histamine Release; Lipid Metabolism; Octanols; Protein Binding; Rats; Serum Albumin, Bovine; Sodium-Potassium-Exchanging ATPase; Solubility; Structure-Activity Relationship | 1981 |
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Surface activity profiling of drugs applied to the prediction of blood-brain barrier permeability.
Topics: Blood-Brain Barrier; Lipid Bilayers; Micelles; Permeability; Pharmaceutical Preparations; Structure-Activity Relationship; Surface Properties | 2004 |
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Relationship between brain tissue partitioning and microemulsion retention factors of CNS drugs.
Topics: Brain; Central Nervous System; Chromatography, Liquid; Emulsions; Mass Spectrometry | 2009 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics | 2010 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
The Effect of Small Molecules on Sterol Homeostasis: Measuring 7-Dehydrocholesterol in Dhcr7-Deficient Neuro2a Cells and Human Fibroblasts.
Topics: Animals; Cell Line; Dehydrocholesterols; Dose-Response Relationship, Drug; Fibroblasts; Homeostasis; Humans; Mice; Molecular Conformation; Neurons; Oxidoreductases Acting on CH-CH Group Donors; Small Molecule Libraries; Sterols; Structure-Activity Relationship | 2016 |
High-dosage and versatile drug therapy with treatment-resistant psychotic patients.
Topics: Adolescent; Adult; Antipsychotic Agents; Chlorpromazine; Doxepin; Female; Hospitals, Psychiatric; Humans; Male; Perphenazine; Psychotic Disorders; Schizophrenia; Thiothixene; Trifluoperazine | 1976 |
Mixed anxiety-depression. Fact or myth?
Topics: Adult; Amitriptyline; Anxiety Disorders; Barbiturates; Chlordiazepoxide; Depression; Doxepin; Female; Humans; Hydroxyzine; Interview, Psychological; Male; Middle Aged; Perphenazine; Personality Inventory; Prognosis | 1974 |
Is amitriptyline + perphenazine superior to doxepin?
Topics: Ambulatory Care; Amitriptyline; Depressive Disorder; Doxepin; Drug Combinations; Drug Therapy, Combination; Humans; Perphenazine | 1983 |
[Determination of basic drugs in blood by RP-HPLC].
Topics: Antidepressive Agents, Tricyclic; Antipsychotic Agents; Chlorpromazine; Chromatography, High Pressure Liquid; Doxepin; Humans; Perphenazine | 1997 |
[A systematic screening and identification method for 29 central nervous system drugs in body fluid by high performance capillary electrophoresis].
Topics: Central Nervous System Agents; Doxepin; Electrophoresis, Capillary; Gastric Juice; Humans; Perphenazine; Phenobarbital | 1997 |