perphenazine and clozapine

perphenazine has been researched along with clozapine in 57 studies

Research

Studies (57)

Timeframe	Studies, this research(%)	All Research%
pre-1990	4 (7.02)	18.7374
1990's	7 (12.28)	18.2507
2000's	24 (42.11)	29.6817
2010's	21 (36.84)	24.3611
2020's	1 (1.75)	2.80

Authors

Authors	Studies
Chiang, GH; Unger, SH	1
Choudhary, MS; Craigo, SC; Meltzer, HY; Monsma, FJ; Roth, BL; Shen, Y; Sibley, DR; Uluer, A	1
Topliss, JG; Yoshida, F	1
Ernsberger, P; Hufeisen, SJ; Jayathilake, K; Kroeze, WK; Meltzer, HY; Popadak, BA; Renock, SM; Roth, BL; Steinberg, S	1
Glennon, RA	1
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY	1
Herrick-Davis, K; Purohit, A; Smith, C; Teitler, M	1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL	1
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J	1
Lombardo, F; Obach, RS; Waters, NJ	1
Ahman, M; Holmén, AG; Wan, H	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Austin, CP; Fidock, DA; Hayton, K; Huang, R; Inglese, J; Jiang, H; Johnson, RL; Su, XZ; Wellems, TE; Wichterman, J; Yuan, J	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM	1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ	1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ	1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ	1
Chen, L; Fei, J; Mei, Y; Ren, S; Yan, SF; Zeng, J; Zhang, JZ	1
Chen, Y; Liu, BF; Liu, S; Liu, X; Qiu, Y; Wang, S; Xu, X; Yu, M; Zhang, G; Zhang, T; Zhao, S	1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL	1
Jadhav, A; Kerns, E; Nguyen, K; Shah, P; Sun, H; Xu, X; Yan, Z; Yu, KR	1
Kabir, M; Kerns, E; Nguyen, K; Shah, P; Sun, H; Wang, Y; Xu, X; Yu, KR	1
Kabir, M; Kerns, E; Neyra, J; Nguyen, K; Nguyễn, ÐT; Shah, P; Siramshetty, VB; Southall, N; Williams, J; Xu, X; Yu, KR	1
Dols, LC; Korf, J; Van Praag, HM	1
Jolicoeur, FB; Marsden, CA; Rivest, R	1
Greenberg, D; Snyder, SH; Yamumura, HI	1
Bochkarev, VK; Paniushkina, SV	1
Hedenmalm, K; Spigset, O	1
Cola, PA; Lee, MA; Mason, EA; Meltzer, HY; Ranjan, R	1
Gerlach, J; Lublin, H; Peacock, L; Solgaard, T	1
Carpenter, WT; Rafal, S; Tsuang, MT	1
Cooke, C; de Leon, J	1
Altendorf, K; Batra, A; Gaertner, HJ; Gaertner, I	1
Hong, X; Wang, X	1
Gil-ad, I; Shiloh, R; Shtaif, B; Weizman, A	1
Lieberman, JA; Stroup, TS	1
Ascher-Svanum, H; Faries, D; Landbloom, R; Swanson, J; Swartz, M; Zhu, B	1
Capuano, G; Davis, SM; Hsiao, JK; Keefe, RS; Lieberman, JA; McEvoy, JP; McGee, MF; Perkins, DO; Reimherr, F; Rosenheck, RA; Stroup, TS; Swartz, MS	1
Allingham, B; Citrome, L; Jaffe, A; Levine, J; Martello, D	1
Swartz, MS	1
Davis, SM; Hsiao, JK; Keefe, RS; Lieberman, JA; McEvoy, JP; Miller, AL; Rosenheck, RA; Stroup, TS; Swartz, MS	1
Ayesa, R; Crespo-Facorro, B; Martínez-Garcia, O; Mata, I; Pérez-Iglesias, R; Ramirez-Bonilla, M; Rodríguez-Sánchez, JM; Vázquez-Barquero, JL	1
Haukka, J; Klaukka, T; Lönnqvist, J; Niskanen, L; Tanskanen, A; Tiihonen, J; Wahlbeck, K	1
Cohen, D; Correll, CU; De Hert, M	1
Abbott, A	1
Friis, S; Haahr, U; Johannessen, JO; Larsen, TK; McGlashan, TH; Melle, I; Opjordsmoen, S; Rund, BR; Simonsen, E; Vaglum, P	1
Dudova, I; Hrdlicka, M; Urbanek, T; Zedkova, I	1
Czernikiewicz, A; Kucharska-Pietura, K; Mortimer, A; Tylec, A	1
Hermes, E; Rosenheck, R	1
Cao, B; Hou, R; Jian, J; Mi, G; Qiu, H; Tang, M; Wang, M	1
Hall, K; Lewitt, M; Melkersson, K	1
Mehtälä, J; Taipale, H; Tanskanen, A; Tiihonen, J	1
Siegfried, N; Stein, DJ; Temmingh, HS; Williams, T	1
Bagheri, M; Barzegar, F; Charati, JY; Farnia, S; Hendouei, N; Hoseini, SD; Mohseni, F; Salehi, A; Shadfar, F; Shaki, F	1

Reviews

3 review(s) available for perphenazine and clozapine

Article	Year
Higher-end serotonin receptors: 5-HT(5), 5-HT(6), and 5-HT(7). Journal of medicinal chemistry, 2003, Jul-03, Volume: 46, Issue:14 Topics: Animals; Humans; Ligands; Receptors, Serotonin; Serotonin Agents; Serotonin Antagonists; Serotonin Receptor Agonists	2003
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
Risperidone versus other antipsychotics for people with severe mental illness and co-occurring substance misuse. The Cochrane database of systematic reviews, 2018, Jan-22, Volume: 1 Topics: Antipsychotic Agents; Benzodiazepines; Clozapine; Diagnosis, Dual (Psychiatry); Humans; Mental Disorders; Olanzapine; Patient Dropouts; Perphenazine; Piperazines; Quetiapine Fumarate; Randomized Controlled Trials as Topic; Risperidone; Schizophrenia; Substance-Related Disorders; Thiazoles	2018

Trials

9 trial(s) available for perphenazine and clozapine

Article	Year
Clozapine versus perphenazine: the value of the biochemical mode of action of neuroleptics in predicting their therapeutic activity. The British journal of psychiatry : the journal of mental science, 1976, Volume: 129 Topics: Adult; Clozapine; Dibenzazepines; Dopamine; Female; Homovanillic Acid; Humans; Hypnotics and Sedatives; Male; Middle Aged; Neurocognitive Disorders; Norepinephrine; Perphenazine; Placebos; Psychotic Disorders; Receptors, Dopamine	1976
Relapse following clozapine withdrawal: effect of neuroleptic drugs and cyproheptadine. Psychopharmacology, 1996, Volume: 124, Issue:1-2 Topics: Adult; Antipsychotic Agents; Clozapine; Cyproheptadine; Female; Humans; Male; Perphenazine; Schizophrenia; Serotonin Antagonists; Substance Withdrawal Syndrome	1996
Clozapine versus typical antipsychotics. A retro- and prospective study of extrapyramidal side effects. Psychopharmacology, 1996, Volume: 124, Issue:1-2 Topics: Adult; Aged; Antipsychotic Agents; Basal Ganglia Diseases; Clozapine; Female; Flupenthixol; Humans; Male; Middle Aged; Perphenazine; Prospective Studies; Schizophrenia	1996
Time to discontinuation of atypical versus typical antipsychotics in the naturalistic treatment of schizophrenia. BMC psychiatry, 2006, Feb-21, Volume: 6 Topics: Adult; Antipsychotic Agents; Benzodiazepines; Bias; Clozapine; Drug Administration Schedule; Episode of Care; Female; Follow-Up Studies; Humans; Male; Olanzapine; Outcome Assessment, Health Care; Perphenazine; Proportional Hazards Models; Research Design; Risperidone; Schizophrenia; Time Factors; Treatment Outcome; United States	2006
Effects of antipsychotic medications on psychosocial functioning in patients with chronic schizophrenia: findings from the NIMH CATIE study. The American journal of psychiatry, 2007, Volume: 164, Issue:3 Topics: Adaptation, Psychological; Antipsychotic Agents; Benzodiazepines; Chronic Disease; Clozapine; Dibenzothiazepines; Follow-Up Studies; Health Status; Humans; National Institute of Mental Health (U.S.); Olanzapine; Patient Dropouts; Perphenazine; Piperazines; Quality of Life; Quetiapine Fumarate; Risperidone; Schizophrenia; Schizophrenic Psychology; Social Adjustment; Thiazoles; Treatment Outcome; United States	2007
Results of phase 3 of the CATIE schizophrenia trial. Schizophrenia research, 2009, Volume: 107, Issue:1 Topics: Adolescent; Adult; Aged; Antipsychotic Agents; Aripiprazole; Benzodiazepines; Chronic Disease; Clozapine; Dibenzothiazepines; Female; Hospitalization; Humans; Male; Middle Aged; Olanzapine; Perphenazine; Piperazines; Quetiapine Fumarate; Quinolones; Risperidone; Schizophrenia; Treatment Outcome; Young Adult	2009
Neurocognitive effectiveness of haloperidol, risperidone, and olanzapine in first-episode psychosis: a randomized, controlled 1-year follow-up comparison. The Journal of clinical psychiatry, 2009, Apr-21, Volume: 70, Issue:5 Topics: Adult; Amisulpride; Antipsychotic Agents; Benzodiazepines; Brain; Clozapine; Cognition Disorders; Female; Follow-Up Studies; Haloperidol; Humans; Male; Neuropsychological Tests; Olanzapine; Perphenazine; Piperazines; Prospective Studies; Psychotic Disorders; Risperidone; Severity of Illness Index; Sulpiride; Thiazoles	2009
Social cognition and visual perception in schizophrenia inpatients treated with first-and second-generation antipsychotic drugs. Clinical schizophrenia & related psychoses, 2012, Volume: 6, Issue:1 Topics: Adolescent; Adult; Affect; Antipsychotic Agents; Awareness; Benzodiazepines; Case-Control Studies; Clozapine; Cues; Discrimination, Psychological; Emotions; Facial Expression; Female; Haloperidol; Hospitalization; Humans; Linear Models; Male; Middle Aged; Olanzapine; Perphenazine; Psychotic Disorders; Retina; Schizophrenia; Schizophrenic Psychology; Social Behavior; Social Perception; Speech Perception; Theory of Mind; Visual Perception; Young Adult	2012
Choice of randomization to clozapine versus other second generation antipsychotics in the CATIE schizophrenia trial. Journal of psychopharmacology (Oxford, England), 2012, Volume: 26, Issue:9 Topics: Adult; Antipsychotic Agents; Benzodiazepines; Clozapine; Dibenzothiazepines; Double-Blind Method; Drug Resistance; Female; Humans; Male; Middle Aged; Olanzapine; Patient Acceptance of Health Care; Patient Dropouts; Patient Participation; Perphenazine; Quetiapine Fumarate; Risperidone; Schizophrenia; Schizophrenic Psychology; Severity of Illness Index; Sex Characteristics	2012

Other Studies

45 other study(ies) available for perphenazine and clozapine

Article	Year
Octanol-physiological buffer distribution coefficients of lipophilic amines by reversed-phase high-performance liquid chromatography and their correlation with biological activity. Journal of medicinal chemistry, 1981, Volume: 24, Issue:3 Topics: Amines; Animals; Buffers; Chromatography, High Pressure Liquid; Histamine Release; Lipid Metabolism; Octanols; Protein Binding; Rats; Serum Albumin, Bovine; Sodium-Potassium-Exchanging ATPase; Solubility; Structure-Activity Relationship	1981
Binding of typical and atypical antipsychotic agents to 5-hydroxytryptamine-6 and 5-hydroxytryptamine-7 receptors. The Journal of pharmacology and experimental therapeutics, 1994, Volume: 268, Issue:3 Topics: Animals; Antipsychotic Agents; Cell Line; Molecular Structure; Rats; Receptors, Serotonin	1994
QSAR model for drug human oral bioavailability. Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13 Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship	2000
H1-histamine receptor affinity predicts short-term weight gain for typical and atypical antipsychotic drugs. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2003, Volume: 28, Issue:3 Topics: Animals; Antipsychotic Agents; Discriminant Analysis; Drug Evaluation, Preclinical; Forecasting; Humans; Protein Binding; Receptors, Histamine H1; Statistics, Nonparametric; Weight Gain	2003
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics. Journal of medicinal chemistry, 2004, Feb-26, Volume: 47, Issue:5 Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution	2004
Stable expression of constitutively activated mutant h5HT6 and h5HT7 serotonin receptors: inverse agonist activity of antipsychotic drugs. Psychopharmacology, 2005, Volume: 179, Issue:2 Topics: Amino Acid Substitution; Antipsychotic Agents; Cell Line; Cyclic AMP; Humans; Mutagenesis, Site-Directed; Mutation; Radioligand Assay; Receptors, Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Transfection	2005
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling. Current drug discovery technologies, 2004, Volume: 1, Issue:4 Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration	2004
Chemical genetics reveals a complex functional ground state of neural stem cells. Nature chemical biology, 2007, Volume: 3, Issue:5 Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells	2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Relationship between brain tissue partitioning and microemulsion retention factors of CNS drugs. Journal of medicinal chemistry, 2009, Mar-26, Volume: 52, Issue:6 Topics: Brain; Central Nervous System; Chromatography, Liquid; Emulsions; Mass Spectrometry	2009
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum. Nature chemical biology, 2009, Volume: 5, Issue:10 Topics: Animals; Antimalarials; ATP Binding Cassette Transporter, Subfamily B, Member 1; Chromosome Mapping; Crosses, Genetic; Dihydroergotamine; Drug Design; Drug Resistance; Humans; Inhibitory Concentration 50; Mutation; Plasmodium falciparum; Quantitative Trait Loci; Transfection	2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models. Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3 Topics:	2008
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species. Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6 Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics	2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development. Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics	2010
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification. Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship	2012
Discovery and characterization of novel, potent, and selective cytochrome P450 2J2 inhibitors. Drug metabolism and disposition: the biological fate of chemicals, 2013, Volume: 41, Issue:1 Topics: Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2J2; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Discovery; Enzyme Inhibitors; Humans; Inhibitory Concentration 50; Kinetics; Microsomes, Liver; Models, Molecular; Molecular Dynamics Simulation; Substrate Specificity	2013
Synthesis and biological investigation of coumarin piperazine (piperidine) derivatives as potential multireceptor atypical antipsychotics. Journal of medicinal chemistry, 2013, Jun-13, Volume: 56, Issue:11 Topics: Animals; Antipsychotic Agents; Avoidance Learning; Biological Availability; Coumarins; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; In Vitro Techniques; Isoxazoles; Lethal Dose 50; Mice; Motor Activity; Prolactin; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT1A; Receptor, Serotonin, 5-HT2A; Receptors, Dopamine D2; Receptors, Dopamine D3; Structure-Activity Relationship; Weight Gain	2013
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics. PloS one, 2016, Volume: 11, Issue:10 Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat	2016
Highly predictive and interpretable models for PAMPA permeability. Bioorganic & medicinal chemistry, 2017, 02-01, Volume: 25, Issue:3 Topics: Artificial Intelligence; Caco-2 Cells; Cell Membrane Permeability; Humans; Models, Biological; Organic Chemicals; Regression Analysis; Support Vector Machine	2017
Predictive models of aqueous solubility of organic compounds built on A large dataset of high integrity. Bioorganic & medicinal chemistry, 2019, 07-15, Volume: 27, Issue:14 Topics: Drug Discovery; Organic Chemicals; Pharmaceutical Preparations; Solubility	2019
Retrospective assessment of rat liver microsomal stability at NCATS: data and QSAR models. Scientific reports, 2020, 11-26, Volume: 10, Issue:1 Topics: Animals; Computer Simulation; Databases, Factual; Drug Discovery; High-Throughput Screening Assays; Liver; Machine Learning; Male; Microsomes, Liver; National Center for Advancing Translational Sciences (U.S.); Pharmaceutical Preparations; Quantitative Structure-Activity Relationship; Rats; Rats, Sprague-Dawley; Retrospective Studies; United States	2020
Use of amfonelic acid to discriminate between classical and atypical neuroleptics and neurotensin: an in vivo voltammetric study. Brain research, 1991, Mar-22, Volume: 544, Issue:1 Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Antipsychotic Agents; Cerebral Ventricles; Clozapine; Corpus Striatum; Electrochemistry; Haloperidol; Injections, Intraventricular; Male; Nalidixic Acid; Naphthyridines; Neurotensin; Perphenazine; Rats; Rats, Inbred Strains; Thioridazine	1991
Antischizophrenic drugs: affinity for muscarinic cholinergic receptor sites in the brain predicts extrapyramidal effects. Journal of psychiatric research, 1974, Volume: 11 Topics: Animals; Antipsychotic Agents; Basal Ganglia Diseases; Binding, Competitive; Brain; Chlorpromazine; Clozapine; Fluphenazine; Guinea Pigs; Haloperidol; Haplorhini; Humans; In Vitro Techniques; Perphenazine; Phenothiazines; Promazine; Rats; Receptors, Cholinergic; Schizophrenia; Thioridazine; Trifluoperazine; Triflupromazine	1974
[Dynamics of integral parameters of the background EEG during treatment with neuroleptics]. Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1982, Volume: 82, Issue:2 Topics: Antipsychotic Agents; Automatism; Brain; Chlorpromazine; Clozapine; Electroencephalography; Haloperidol; Humans; Perphenazine; Schizophrenia; Trifluoperazine	1982
Hyponatremia during treatment with clomipramine, perphenazine, or clozapine: study of therapeutic drug monitoring samples. Journal of clinical psychopharmacology, 1996, Volume: 16, Issue:5 Topics: Adult; Antidepressive Agents, Tricyclic; Antipsychotic Agents; Clomipramine; Clozapine; Drug Monitoring; Electrolytes; Female; Humans; Hyponatremia; Male; Perphenazine	1996
A dilemma born of progress: switching from clozapine to a newer antipsychotic. The American journal of psychiatry, 1999, Volume: 156, Issue:7 Topics: Adult; Antipsychotic Agents; Attitude to Health; Benzodiazepines; Clozapine; Drug Monitoring; Humans; Male; Olanzapine; Patient Compliance; Perphenazine; Pirenzepine; Quality of Life; Risk Assessment; Schizophrenia; Schizophrenic Psychology; Treatment Outcome	1999
Adding other antipsychotics to clozapine. The Journal of clinical psychiatry, 1999, Volume: 60, Issue:10 Topics: Acute Disease; Antipsychotic Agents; Clozapine; Drug Administration Schedule; Drug Interactions; Drug Therapy, Combination; Humans; Male; Middle Aged; Perphenazine; Psychoses, Substance-Induced; Psychotic Disorders	1999
Relevance of liver enzyme elevations with four different neuroleptics: a retrospective review of 7,263 treatment courses. Journal of clinical psychopharmacology, 2001, Volume: 21, Issue:2 Topics: Alanine Transaminase; Antipsychotic Agents; Aspartate Aminotransferases; Chi-Square Distribution; Clozapine; Female; gamma-Glutamyltransferase; Glutamate Dehydrogenase; Haloperidol; Humans; Liver; Male; Perazine; Perphenazine; Retrospective Studies; Schizophrenia; Statistics, Nonparametric	2001
Agranulocytosis and neutropenia with typical and atypical neuroleptics. The American journal of psychiatry, 2001, Volume: 158, Issue:10 Topics: Adult; Agranulocytosis; Antipsychotic Agents; Benzodiazepines; Clozapine; Female; Humans; Leukocyte Count; Neutropenia; Olanzapine; Perphenazine; Pirenzepine; Risperidone; Schizophrenia	2001
Evaluation of the neurotoxic activity of typical and atypical neuroleptics: relevance to iatrogenic extrapyramidal symptoms. Cellular and molecular neurobiology, 2001, Volume: 21, Issue:6 Topics: Animals; Antipsychotic Agents; Basal Ganglia Diseases; Brain; Cell Cycle; Cell Survival; Clozapine; DNA Fragmentation; Dopamine; Dose-Response Relationship, Drug; Dyskinesia, Drug-Induced; Female; Haloperidol; Humans; Iatrogenic Disease; Mice; Mice, Inbred ICR; Neurons; Neurotoxins; Perphenazine; Pregnancy; Risperidone; Tumor Cells, Cultured	2001
Schizophrenia, VI: Treatments. The American journal of psychiatry, 2003, Volume: 160, Issue:10 Topics: Antipsychotic Agents; Benzodiazepines; Clozapine; Dibenzothiazepines; Humans; Olanzapine; Perphenazine; Piperazines; Pirenzepine; Quetiapine Fumarate; Randomized Controlled Trials as Topic; Risperidone; Schizophrenia; Thiazoles; Treatment Outcome	2003
Did CATIE influence antipsychotic use? Psychiatric services (Washington, D.C.), 2008, Volume: 59, Issue:5 Topics: Antipsychotic Agents; Benzodiazepines; Clozapine; Dibenzothiazepines; Drug Therapy; Haloperidol; Humans; Olanzapine; Perphenazine; Piperazines; Psychotic Disorders; Quetiapine Fumarate; Risperidone; Schizophrenia; Thiazoles	2008
Introduction to the CATIE special section. Psychiatric services (Washington, D.C.), 2008, Volume: 59, Issue:5 Topics: Antipsychotic Agents; Body Weight; Clinical Trials as Topic; Clozapine; Cognition; Health Policy; Humans; Perphenazine; Schizophrenia	2008
11-year follow-up of mortality in patients with schizophrenia: a population-based cohort study (FIN11 study). Lancet (London, England), 2009, Aug-22, Volume: 374, Issue:9690 Topics: Adult; Age Distribution; Aged; Antipsychotic Agents; Case-Control Studies; Cause of Death; Clozapine; Dibenzothiazepines; Drug Utilization; Female; Finland; Follow-Up Studies; Health Status Disparities; Humans; Life Expectancy; Male; Middle Aged; Patient Readmission; Perphenazine; Proportional Hazards Models; Quetiapine Fumarate; Registries; Risk Factors; Schizophrenia; Sex Distribution; Time Factors	2009
Do antipsychotic medications reduce or increase mortality in schizophrenia? A critical appraisal of the FIN-11 study. Schizophrenia research, 2010, Volume: 117, Issue:1 Topics: Adult; Antipsychotic Agents; Clozapine; Dibenzothiazepines; Female; Finland; Haloperidol; Humans; Male; Perphenazine; Quetiapine Fumarate; Risperidone; Schizophrenia; Suicide; Survival Rate	2010
Schizophrenia: The drug deadlock. Nature, 2010, Nov-11, Volume: 468, Issue:7321 Topics: Animals; Antipsychotic Agents; Clinical Trials as Topic; Clozapine; Cognition; Dopamine D2 Receptor Antagonists; Drug Evaluation, Preclinical; Drug Industry; Humans; Perphenazine; Psychotic Disorders; Receptor, Serotonin, 5-HT2A; Receptors, Dopamine D2; Schizophrenia; Serotonin 5-HT2 Receptor Antagonists	2010
Stability of medication in early psychosis: a comparison between second-generation and low-dose first-generation antipsychotics. Early intervention in psychiatry, 2009, Volume: 3, Issue:1 Topics: Adolescent; Adult; Aged; Antipsychotic Agents; Benzodiazepines; Chi-Square Distribution; Clopenthixol; Clozapine; Female; Humans; Imidazoles; Indoles; Kaplan-Meier Estimate; Male; Middle Aged; Olanzapine; Perphenazine; Psychotic Disorders; Risperidone; Statistics, Nonparametric; Time Factors; Young Adult	2009
Onset of action of atypical and typical antipsychotics in the treatment of adolescent schizophrenic psychoses. Neuro endocrinology letters, 2011, Volume: 32, Issue:5 Topics: Adolescent; Antipsychotic Agents; Benzodiazepines; Clozapine; Dibenzothiazepines; Female; Haloperidol; Humans; Male; Medical Records; Olanzapine; Perphenazine; Piperazines; Psychotic Disorders; Quetiapine Fumarate; Risperidone; Schizophrenia; Sulpiride; Thiazoles; Time Factors; Treatment Outcome	2011
Effects of antipsychotics on bone mineral density and prolactin levels in patients with schizophrenia: a 12-month prospective study. Human psychopharmacology, 2014, Volume: 29, Issue:2 Topics: Adult; Alkaline Phosphatase; Antipsychotic Agents; Aripiprazole; Bone Density; Chlorpromazine; Clozapine; Dibenzothiazepines; Estrogens; Female; Humans; Male; Middle Aged; Osteoporosis; Perphenazine; Piperazines; Prolactin; Prospective Studies; Quetiapine Fumarate; Quinolones; Risk Factors; Schizophrenia; Sulpiride	2014
Higher serum concentrations of tyrosine and glutamate in schizophrenia patients treated with clozapine, compared to in those treated with conventional antipsychotics. Neuro endocrinology letters, 2015, Volume: 36, Issue:5 Topics: Adult; Amino Acids; Antipsychotic Agents; Chromatography, Ion Exchange; Clopenthixol; Clozapine; Cohort Studies; Female; Glutamic Acid; Haloperidol; Humans; Insulin Resistance; Male; Middle Aged; Perphenazine; Prospective Studies; Psychotic Disorders; Schizophrenia; Thioridazine; Tyrosine	2015
Comparative Effectiveness of Antipsychotic Drugs for Rehospitalization in Schizophrenia-A Nationwide Study With 20-Year Follow-up. Schizophrenia bulletin, 2018, 10-17, Volume: 44, Issue:6 Topics: Adult; Aged; Antipsychotic Agents; Clozapine; Female; Finland; Flupenthixol; Follow-Up Studies; Humans; Incidence; Male; Middle Aged; Olanzapine; Paliperidone Palmitate; Patient Readmission; Perphenazine; Prevalence; Schizophrenia; Secondary Prevention; Young Adult	2018
Alterations in oxidative stress markers and its correlation with clinical findings in schizophrenic patients consuming perphenazine, clozapine and risperidone. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2018, Volume: 103 Topics: Adolescent; Adult; Aged; Antipsychotic Agents; Biomarkers; Clozapine; Humans; Middle Aged; Oxidative Stress; Perphenazine; Psychiatric Status Rating Scales; Risperidone; Schizophrenia; Young Adult	2018