Page last updated: 2024-09-03

peroxynitrous acid and tryptophan

peroxynitrous acid has been researched along with tryptophan in 32 studies

Compound Research Comparison

Studies
(peroxynitrous acid)
Trials
(peroxynitrous acid)
Recent Studies (post-2010)
(peroxynitrous acid)
Studies
(tryptophan)
Trials
(tryptophan)
Recent Studies (post-2010) (tryptophan)
3,303211,23032,7629367,183

Protein Interaction Comparison

ProteinTaxonomyperoxynitrous acid (IC50)tryptophan (IC50)
MyeloperoxidaseHomo sapiens (human)2.25

Research

Studies (32)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's19 (59.38)29.6817
2010's11 (34.38)24.3611
2020's2 (6.25)2.80

Authors

AuthorsStudies
Herold, S; Mehl, M; Shivashankar, K1
Amici, M; Angeletti, M; Eleuteri, AM; Fioretti, E; Lupidi, G1
Cakýcý, Y; Kanzýk, Y; Sariahmetoglu, M; Townshend, A; Wheatley, RA1
Herold, S1
Fujimura, T; Matsumoto, T; Murayama, K; Taka, H; Yamakura, F1
Balasubramanian, D; Chalasani, M; Lakshmanan, J; Thiagarajan, G1
Friesen, MD; Gilibert, I; Mower, HF; Ohshima, H; Sawa, T; Suzuki, T1
Angeletti, M; Eleuteri, AM; Fioretti, E; Lupidi, G; Montecchia, F; Pucciarelli, S; Spina, M1
Liang, YD; Song, JF1
Kirsch, M; Lehnig, M2
Fujimura, T; Ikeda, K; Imai, T; Matsumoto, T; Murayama, K; Taka, H; Takamori, K; Tamaki, M; Watanabe, E; Yamakura, F1
Ikeda, K; Iwai, H; Matsumoto, T; Mineki, R; Ogawa, H; Taka, H; Takamori, K; Yamakura, F; Yukihiro Hiraoka, B1
Ducrocq, C; Peyrot, F2
Hirose, M; Ishii, Y; Ito, R; Iwasaki, Y; Katsumata, T; Nakazawa, H; Nishikawa, A; Ogara, A; Saito, K; Umemura, T1
Bregere, C; Gallaher, TK; Rebrin, I; Sohal, RS1
Abd-Allah, GM; Mariee, AD1
Barros, MP; Bechara, EJ; Dyszy, FH; Faria, PA; Mano, CM; Nantes, IL; Nascimento, OR; Prieto, T1
Baba, T; Ikeda, K; Kawasaki, H; Ogawa, H; Shigenaga, A; Takamori, K; Yamakura, F1
Costa, RC; Harasimowicz, J; Marques, KL; Prior, JA; Rodrigues, SS; Santos, JL; Silva, AF1
Gibbons, NC; Lüdemann, J; Martinez, A; Rokos, H; Salem, MA; Schallreuter, KU; Slominski, R1
Elwary, SM; Gibbons, NC; Healey, AR; Maitland, DJ; Marsch, E; Salem, MA; Schallreuter, KU1
Fort, PE; Green, KM; Nagaraj, RH; Nahomi, RB; Palmer, A1
Iizumi, K; Kamata, Y; Kamo, A; Kawasaki, H; Kimura, U; Ogawa, H; Shigenaga, A; Takamori, K; Tominaga, M; Yamakura, F1
da Silva, JC; Leitão, JM; Simões, EF1
Alavianmehr, MM; Ghahramani, M; Khoshaman, K; Yousefi, R1
Alam, K; Arfat, MY; Arif, Z; Chaturvedi, SK1
Hagiwara, A; Honda, R; Ikemoto, N; Kanome, M; Matsuda, Y; Matsui, R; Terashima, M; Togitani, T1
Chen, LW; Chen, PH; Tsay, TB1
Kosmachevskaya, OV; Nasybullina, EI; Novikova, NN; Shumaev, KB; Topunov, AF1
Arasimowicz-Jelonek, M; Floryszak-Wieczorek, J; Jagodzik, P; Mattoo, A; Polcyn, W; Płóciennik, A; Sobieszczuk-Nowicka, E1

Reviews

2 review(s) available for peroxynitrous acid and tryptophan

ArticleYear
Potential role of tryptophan derivatives in stress responses characterized by the generation of reactive oxygen and nitrogen species.
    Journal of pineal research, 2008, Volume: 45, Issue:3

    Topics: Animals; Antioxidants; Carcinogens; Humans; Kynuramine; Kynurenine; Melatonin; Mutagens; Nitric Oxide Donors; Nitrogen Dioxide; Nitroso Compounds; Oxidation-Reduction; Peroxynitrous Acid; Reactive Nitrogen Species; Reactive Oxygen Species; Serotonin; Stress, Physiological; Tryptophan

2008
Detection and characterization of peroxynitrite-induced modifications of tyrosine, tryptophan, and methionine residues by tandem mass spectrometry.
    Methods in enzymology, 2008, Volume: 441

    Topics: Animals; Humans; Methionine; Oligopeptides; Peroxynitrous Acid; Tandem Mass Spectrometry; Tryptophan; Tyrosine

2008

Other Studies

30 other study(ies) available for peroxynitrous acid and tryptophan

ArticleYear
Myoglobin scavenges peroxynitrite without being significantly nitrated.
    Biochemistry, 2002, Nov-12, Volume: 41, Issue:45

    Topics: Animals; Apoproteins; Free Radical Scavengers; Globins; Immunohistochemistry; Metmyoglobin; Myoglobin; Nitrates; Oxyhemoglobins; Peroxynitrous Acid; Tryptophan; Tyrosine

2002
Peroxynitrite-induced oxidation and its effects on isolated proteasomal systems.
    Free radical biology & medicine, 2003, Apr-15, Volume: 34, Issue:8

    Topics: Anilino Naphthalenesulfonates; Animals; Blotting, Western; Brain; Caseins; Cattle; Cysteine Endopeptidases; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Free Radicals; Kinetics; Multienzyme Complexes; Oxygen; Peptides; Peroxynitrous Acid; Proteasome Endopeptidase Complex; Protein Binding; Protein Conformation; Spectrometry, Fluorescence; Thymus Gland; Tryptophan; Tyrosine

2003
Evaluation of the antioxidant effect of melatonin by flow injection analysis-luminol chemiluminescence.
    Pharmacological research, 2003, Volume: 48, Issue:4

    Topics: Antioxidants; Flow Injection Analysis; Hydrogen Peroxide; Hydroxyl Radical; Luminescent Measurements; Luminol; Melatonin; Peroxynitrous Acid; Serotonin; Sodium Hypochlorite; Solutions; Superoxides; Tryptophan; Water

2003
Nitrotyrosine, dityrosine, and nitrotryptophan formation from metmyoglobin, hydrogen peroxide, and nitrite.
    Free radical biology & medicine, 2004, Mar-01, Volume: 36, Issue:5

    Topics: Hydrogen Peroxide; Methemoglobin; Metmyoglobin; Myoglobin; Nitrites; Peroxidase; Peroxynitrous Acid; Tryptophan; Tyrosine

2004
6-Nitrotryptophan: a specific reaction product of tryptophan residue in human Cu, Zn-SOD treated with peroxynitrite.
    Advances in experimental medicine and biology, 2003, Volume: 527

    Topics: Amino Acid Sequence; Binding Sites; Humans; In Vitro Techniques; Oxidation-Reduction; Peptide Fragments; Peroxynitrous Acid; Spectrophotometry; Superoxide Dismutase; Trypsin; Tryptophan

2003
Peroxynitrite reaction with eye lens proteins: alpha-crystallin retains its activity despite modification.
    Investigative ophthalmology & visual science, 2004, Volume: 45, Issue:7

    Topics: alpha-Crystallins; Animals; Cattle; Lens, Crystalline; Molecular Chaperones; Oxidative Stress; Peroxynitrous Acid; Tryptophan; Tyrosine

2004
Nitration and nitrosation of N-acetyl-L-tryptophan and tryptophan residues in proteins by various reactive nitrogen species.
    Free radical biology & medicine, 2004, Sep-01, Volume: 37, Issue:5

    Topics: Chromatography, High Pressure Liquid; Nitrates; Nitrosation; Nitroso Compounds; Peroxynitrous Acid; Proteins; Reactive Nitrogen Species; Tryptophan

2004
Peroxynitrite-mediated oxidation of the C85S/C152E mutant of dihydrofolate reductase from Escherichia coli: functional and structural effects.
    Archives of biochemistry and biophysics, 2005, Feb-15, Volume: 434, Issue:2

    Topics: Blotting, Western; Calorimetry, Differential Scanning; Chromatography, Gel; Chromatography, High Pressure Liquid; Cysteine; Cystine; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Immunoblotting; Mutation; Oxidative Stress; Oxygen; Peroxynitrous Acid; Reactive Oxygen Species; Spectrometry, Fluorescence; Temperature; Tetrahydrofolate Dehydrogenase; Thermodynamics; Time Factors; Tryptophan; Tyrosine

2005
Flow-injection chemiluminescence determination of tryptophan through its peroxidation and epoxidation by peroxynitrous acid.
    Journal of pharmaceutical and biomedical analysis, 2005, Jun-01, Volume: 38, Issue:1

    Topics: Epoxy Compounds; Flow Injection Analysis; Hydrogen Peroxide; Luminescent Measurements; Peroxynitrous Acid; Sodium Nitrite; Tryptophan

2005
Generation of peroxynitrite from reaction of N-acetyl-N-nitrosotryptophan with hydrogen peroxide over a wide range of pH values.
    Organic & biomolecular chemistry, 2005, Jun-07, Volume: 3, Issue:11

    Topics: Hydrogen Peroxide; Hydrogen-Ion Concentration; Kinetics; Magnetic Resonance Spectroscopy; Nitrosamines; Peroxynitrous Acid; Quantum Theory; Spectrophotometry, Ultraviolet; Tryptophan

2005
Nitrated and oxidized products of a single tryptophan residue in human Cu,Zn-superoxide dismutase treated with either peroxynitrite-carbon dioxide or myeloperoxidase-hydrogen peroxide-nitrite.
    Journal of biochemistry, 2005, Volume: 138, Issue:1

    Topics: Amino Acids; Chromatography, High Pressure Liquid; Humans; Hydrogen Peroxide; Hydrogen-Ion Concentration; Kinetics; Magnetic Resonance Spectroscopy; Mass Spectrometry; Oxidation-Reduction; Peptide Fragments; Peroxidase; Peroxynitrous Acid; Spectrometry, Fluorescence; Superoxide Dismutase; Tryptophan

2005
Detection of 6-nitrotryptophan in proteins by Western blot analysis and its application for peroxynitrite-treated PC12 cells.
    Nitric oxide : biology and chemistry, 2007, Volume: 16, Issue:1

    Topics: Animals; Antibodies; Antibody Formation; Antibody Specificity; Blotting, Western; Chromatography, Liquid; Electrophoresis, Polyacrylamide Gel; Mass Spectrometry; PC12 Cells; Peroxynitrous Acid; Proteins; Rats; Tryptophan

2007
Nitrosation of N-terminally blocked tryptophan and tryptophan-containing peptides by peroxynitrite.
    Chembiochem : a European journal of chemical biology, 2007, Jan-22, Volume: 8, Issue:2

    Topics: Fluorescein; Indoles; Molecular Sequence Data; Molecular Structure; Nitrosation; Peptides; Peroxynitrous Acid; Tryptophan

2007
Quantification of nitrated tryptophan in proteins and tissues by high-performance liquid chromatography with electrospray ionization tandem mass spectrometry.
    Journal of pharmaceutical and biomedical analysis, 2007, May-09, Volume: 44, Issue:1

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Cattle; Chromatography, High Pressure Liquid; Isomerism; Liver; Male; Mice; Mice, Inbred Strains; Molecular Structure; Nitrates; Peroxynitrous Acid; Protein Binding; Proteins; Reproducibility of Results; Sensitivity and Specificity; Serum Albumin, Bovine; Specific Pathogen-Free Organisms; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry; Tryptophan

2007
15N-CIDNP investigations during tryptophan, N-acetyl-L-tryptophan, and melatonin nitration with reactive nitrogen species.
    Free radical research, 2007, Volume: 41, Issue:5

    Topics: Magnetic Resonance Spectroscopy; Melatonin; Molecular Structure; Nitrates; Nitrogen; Peroxynitrous Acid; Photochemistry; Reactive Nitrogen Species; Tryptophan

2007
Nitrite-mediated inactivation of human plasma paraoxonase-1: possible beneficial effect of aromatic amino acids.
    Applied biochemistry and biotechnology, 2008, Volume: 150, Issue:3

    Topics: Amino Acids, Aromatic; Aryldialkylphosphatase; Catalase; Enzyme Activation; Glutathione; Humans; Nitrites; Peroxynitrous Acid; Tryptophan

2008
Superoxide radical protects liposome-contained cytochrome c against oxidative damage promoted by peroxynitrite and free radicals.
    Free radical biology & medicine, 2009, Sep-15, Volume: 47, Issue:6

    Topics: Cytochromes c; Electron Spin Resonance Spectroscopy; Heme; Lipid Peroxidation; Nitrosation; Oxidation-Reduction; Oxidative Stress; Peroxidase; Peroxynitrous Acid; Protein Processing, Post-Translational; Protein Structure, Secondary; Spectrophotometry; Superoxides; Tryptophan; Unilamellar Liposomes

2009
Mass spectrometric identification of tryptophan nitration sites on proteins in peroxynitrite-treated lysates from PC12 cells.
    Free radical biology & medicine, 2011, Feb-01, Volume: 50, Issue:3

    Topics: Amino Acid Sequence; Animals; Cell Extracts; Chromatography, Liquid; Enzymes; HSP90 Heat-Shock Proteins; Models, Molecular; Molecular Sequence Data; PC12 Cells; Peroxynitrous Acid; Protein Structure, Tertiary; Rats; Tandem Mass Spectrometry; Tryptophan; Tyrosine

2011
Chemiluminometric evaluation of melatonin and selected melatonin precursors' interaction with reactive oxygen and nitrogen species.
    Analytical biochemistry, 2012, Jan-01, Volume: 420, Issue:1

    Topics: 5-Hydroxytryptophan; Automation, Laboratory; Chemistry Techniques, Analytical; Equipment Design; Free Radical Scavengers; Hydrogen Peroxide; Hydroxyl Radical; Luminescence; Luminol; Melatonin; Peroxynitrous Acid; Reactive Oxygen Species; Tryptophan

2012
Blunted epidermal L-tryptophan metabolism in vitiligo affects immune response and ROS scavenging by Fenton chemistry, part 1: Epidermal H2O2/ONOO(-)-mediated stress abrogates tryptophan hydroxylase and dopa decarboxylase activities, leading to low seroton
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2012, Volume: 26, Issue:6

    Topics: Adult; Calcium Channels, L-Type; Cells, Cultured; Dopa Decarboxylase; Epidermis; Humans; Hydrogen Peroxide; Melatonin; Middle Aged; Oxidation-Reduction; Peroxynitrous Acid; Reactive Oxygen Species; Serotonin; Tryptophan; Tryptophan Hydroxylase; Vitiligo

2012
Blunted epidermal L-tryptophan metabolism in vitiligo affects immune response and ROS scavenging by Fenton chemistry, part 2: Epidermal H2O2/ONOO(-)-mediated stress in vitiligo hampers indoleamine 2,3-dioxygenase and aryl hydrocarbon receptor-mediated imm
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2012, Volume: 26, Issue:6

    Topics: Computer Simulation; Epidermis; Humans; Hydrogen Peroxide; Indoleamine-Pyrrole 2,3,-Dioxygenase; Oxidative Stress; Peroxynitrous Acid; Receptors, Aryl Hydrocarbon; Signal Transduction; T-Lymphocytes, Regulatory; Tryptophan; Vitiligo

2012
Pro-inflammatory cytokines downregulate Hsp27 and cause apoptosis of human retinal capillary endothelial cells.
    Biochimica et biophysica acta, 2014, Volume: 1842, Issue:2

    Topics: Apoptosis; Blotting, Western; Cells, Cultured; Cytokines; Dose-Response Relationship, Drug; Down-Regulation; Endothelial Cells; Glucose; Heat-Shock Proteins; HSP27 Heat-Shock Proteins; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Inflammation Mediators; Interferon-gamma; Interleukin-1beta; Molecular Chaperones; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type II; Peroxynitrous Acid; Reactive Oxygen Species; Retina; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; Tryptophan; Tumor Necrosis Factor-alpha

2014
Importance of tryptophan nitration of carbonic anhydrase III for the morbidity of atopic dermatitis.
    Free radical biology & medicine, 2014, Volume: 73

    Topics: Animals; Carbonic Anhydrase III; Cell Line; Dermatitis, Atopic; Disease Models, Animal; Humans; Immunohistochemistry; Inflammation; Keratin-2; Keratinocytes; Male; Mice; Mice, Inbred C57BL; Mice, Inbred ICR; Peroxynitrous Acid; Phosphopyruvate Hydratase; Rats; Reactive Nitrogen Species; Skin; Tryptophan

2014
Carbon dots from tryptophan doped glucose for peroxynitrite sensing.
    Analytica chimica acta, 2014, Dec-10, Volume: 852

    Topics: Carbon; Fluorescent Dyes; Glucose; Humans; Limit of Detection; Peroxynitrous Acid; Spectrometry, Fluorescence; Tryptophan

2014
The impact of calcium ion on structure and aggregation propensity of peroxynitrite-modified lens crystallins: new insights into the pathogenesis of cataract disorders.
    Colloids and surfaces. B, Biointerfaces, 2015, Jan-01, Volume: 125

    Topics: Animals; Benzothiazoles; Calcium; Cattle; Crystallins; Hydrophobic and Hydrophilic Interactions; Lens, Crystalline; Oxidants; Peroxynitrous Acid; Protein Aggregates; Protein Carbonylation; Protein Stability; Proteolysis; Spectrometry, Fluorescence; Thiazoles; Tryptophan; Tyrosine

2015
Peroxynitrite-induced structural perturbations in human IgG: A physicochemical study.
    Archives of biochemistry and biophysics, 2016, 08-01, Volume: 603

    Topics: Arthritis, Rheumatoid; Calorimetry, Differential Scanning; Circular Dichroism; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Humans; Immunoglobulin G; Inflammation; Light; Microscopy, Fluorescence; Oxygen; Peroxynitrous Acid; Protein Structure, Secondary; Scattering, Radiation; Sepharose; Spectrophotometry; Spectroscopy, Fourier Transform Infrared; Temperature; Tryptophan; Tyrosine

2016
Designing antioxidant peptides based on the antioxidant properties of the amino acid side-chains.
    Food chemistry, 2018, Apr-15, Volume: 245

    Topics: Amino Acids; Antioxidants; Hydrophobic and Hydrophilic Interactions; Myoglobin; Peptides; Peroxides; Peroxynitrous Acid; Protein Engineering; Reactive Nitrogen Species; Reactive Oxygen Species; Structure-Activity Relationship; Tryptophan; Tyrosine

2018
Aryl hydrocarbon receptor ligands enhance lung immunity through intestinal IKKβ pathways.
    Journal of translational medicine, 2019, 09-05, Volume: 17, Issue:1

    Topics: Administration, Oral; Animals; Anti-Bacterial Agents; Colony Count, Microbial; I-kappa B Kinase; Indoles; Intestinal Mucosa; Intestines; Lactobacillus plantarum; Ligands; Lung; Macrophages, Alveolar; Mice, Inbred C57BL; NF-kappa B; Peroxynitrous Acid; Phagocytosis; Pneumonia; Pseudomonas aeruginosa; Reactive Oxygen Species; Receptors, Aryl Hydrocarbon; Signal Transduction; Tryptophan

2019
Protective Effect of Dinitrosyl Iron Complexes Bound with Hemoglobin on Oxidative Modification by Peroxynitrite.
    International journal of molecular sciences, 2021, Dec-20, Volume: 22, Issue:24

    Topics: Animals; Cattle; Electron Spin Resonance Spectroscopy; Humans; Iron; Methemoglobin; Nitrogen Oxides; Oxidation-Reduction; Peroxynitrous Acid; Tryptophan; Tyrosine

2021
Dynamics of nitration during dark-induced leaf senescence in Arabidopsis reveals proteins modified by tryptophan nitration.
    Journal of experimental botany, 2022, 11-02, Volume: 73, Issue:19

    Topics: Arabidopsis; Nitric Oxide; Peroxynitrous Acid; Plant Senescence; Plants; RNA; Tryptophan; Tyrosine

2022