Page last updated: 2024-09-03

peroxynitrous acid and thioctic acid

peroxynitrous acid has been researched along with thioctic acid in 7 studies

Compound Research Comparison

Studies
(peroxynitrous acid)
Trials
(peroxynitrous acid)
Recent Studies (post-2010)
(peroxynitrous acid)
Studies
(thioctic acid)
Trials
(thioctic acid)
Recent Studies (post-2010) (thioctic acid)
3,303211,2304,6283221,947

Protein Interaction Comparison

ProteinTaxonomyperoxynitrous acid (IC50)thioctic acid (IC50)
Ubiquitin-like modifier activating enzyme 2Homo sapiens (human)2.68
SUMO1 activating enzyme subunit 1Homo sapiens (human)2.68
hexokinaseTrypanosoma brucei brucei TREU9270.2008
SUMO-conjugating enzyme UBC9Homo sapiens (human)2.68
eukaryotic translation initiation factor 4 gamma 1 isoform 4Homo sapiens (human)16.56
eukaryotic translation initiation factor 4E isoform 1Mus musculus (house mouse)16.56
VifHuman immunodeficiency virus 17.67
TatHuman immunodeficiency virus 15.891
DNA dC->dU-editing enzyme APOBEC-3G isoform 1Homo sapiens (human)7.67
bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferaseMycobacterium tuberculosis H37Rv3.91

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's6 (85.71)29.6817
2010's1 (14.29)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Radi, R; Trujillo, M1
Khramtsov, VV; Sergeeva, SV; Slepneva, IA1
Bryk, R; Erdjument-Bromage, H; Lima, CD; Nathan, C; Tempst, P1
Bast, A; Haenen, GR; Rezk, BM; van der Vijgh, WJ1
Bartesaghi, S; Folkes, L; Kalyanaraman, B; Radi, R; Trujillo, M; Wardman, P1
Jia, Z; Li, Y; Misra, BR; Misra, HP; Vitto, MJ; Zhu, H1
Barbieri, M; Caporaso, I; D'Amico, F; Marfella, R; Paolisso, G; Paolisso, P; Rizzo, MR; Sacra, C; Santamaria, M; Santulli, G; Sardu, C; Testa, N1

Trials

1 trial(s) available for peroxynitrous acid and thioctic acid

ArticleYear
Effects of Alpha Lipoic Acid on Multiple Cytokines and Biomarkers and Recurrence of Atrial Fibrillation Within 1 Year of Catheter Ablation.
    The American journal of cardiology, 2017, May-01, Volume: 119, Issue:9

    Topics: Aged; Antioxidants; Atrial Fibrillation; Biomarkers; Blood Glucose; C-Reactive Protein; Catheter Ablation; Cholesterol, HDL; Cholesterol, LDL; Cytokines; Double-Blind Method; Female; Humans; Interleukin-10; Interleukin-6; Interleukin-8; Male; Middle Aged; Natriuretic Peptide, Brain; Peptide Fragments; Peroxynitrous Acid; Postoperative Care; Recurrence; Thioctic Acid; Treatment Outcome; Triglycerides; Tumor Necrosis Factor-alpha; Tyrosine

2017

Other Studies

6 other study(ies) available for peroxynitrous acid and thioctic acid

ArticleYear
Peroxynitrite reaction with the reduced and the oxidized forms of lipoic acid: new insights into the reaction of peroxynitrite with thiols.
    Archives of biochemistry and biophysics, 2002, Jan-01, Volume: 397, Issue:1

    Topics: 8,11,14-Eicosatrienoic Acid; Antioxidants; Dose-Response Relationship, Drug; Hydrogen-Ion Concentration; Kinetics; Mass Spectrometry; Models, Chemical; Oxygen; Peroxynitrous Acid; Protein Binding; Sulfhydryl Compounds; Sulfonic Acids; Thioctic Acid; Time Factors

2002
Effect of selenolipoic acid on peroxynitrite-dependent inactivation of NADPH-cytochrome P450 reductase.
    Free radical research, 2001, Volume: 35, Issue:5

    Topics: Animals; Enzyme Inhibitors; Free Radical Scavengers; In Vitro Techniques; Kinetics; Microsomes, Liver; Molsidomine; NADP; NADPH-Ferrihemoprotein Reductase; Nitric Oxide Donors; Peroxynitrous Acid; Rats; Sulfhydryl Compounds; Thioctic Acid

2001
Metabolic enzymes of mycobacteria linked to antioxidant defense by a thioredoxin-like protein.
    Science (New York, N.Y.), 2002, Feb-08, Volume: 295, Issue:5557

    Topics: Acyltransferases; Amino Acid Sequence; Antioxidants; Binding Sites; Catalysis; Cloning, Molecular; Crystallization; Crystallography, X-Ray; Dihydrolipoamide Dehydrogenase; Hydrogen Bonding; Hydrogen Peroxide; Models, Molecular; Molecular Sequence Data; Mycobacterium tuberculosis; NAD; Oxidation-Reduction; Oxidoreductases; Peroxidases; Peroxiredoxins; Peroxynitrous Acid; Protein Conformation; Protein Folding; Protein Structure, Quaternary; Thioctic Acid; Thioredoxins

2002
Lipoic acid protects efficiently only against a specific form of peroxynitrite-induced damage.
    The Journal of biological chemistry, 2004, Mar-12, Volume: 279, Issue:11

    Topics: Antioxidants; Dose-Response Relationship, Drug; Glutathione; Glutathione S-Transferase pi; Glutathione Transferase; Hypochlorous Acid; Inhibitory Concentration 50; Isoenzymes; Models, Biological; Models, Chemical; Nitric Oxide; Oxygen; Peroxynitrous Acid; Potassium; Protein Binding; Rhodamines; Sulfur; Thioctic Acid; Tyrosine

2004
Peroxynitrite-derived carbonate and nitrogen dioxide radicals readily react with lipoic and dihydrolipoic acid.
    Free radical biology & medicine, 2005, Jul-15, Volume: 39, Issue:2

    Topics: Antioxidants; Carbonates; Chromatography, High Pressure Liquid; Computer Simulation; Dimerization; Dose-Response Relationship, Drug; Free Radicals; Kinetics; Liposomes; Nitric Oxide; Nitrogen Dioxide; Oxygen; Peroxynitrous Acid; Sulfhydryl Compounds; Temperature; Thioctic Acid; Tyrosine

2005
Alpha-lipoic acid potently inhibits peroxynitrite-mediated DNA strand breakage and hydroxyl radical formation: implications for the neuroprotective effects of alpha-lipoic acid.
    Molecular and cellular biochemistry, 2009, Volume: 323, Issue:1-2

    Topics: Animals; Antioxidants; DNA Breaks, Double-Stranded; Electron Spin Resonance Spectroscopy; Humans; Hydroxyl Radical; Molsidomine; Neuroprotective Agents; Nitric Oxide Donors; Oxidative Stress; Oxygen Consumption; Peroxynitrous Acid; Thioctic Acid

2009