Page last updated: 2024-09-03

peroxynitrous acid and propofol

peroxynitrous acid has been researched along with propofol in 6 studies

Compound Research Comparison

Studies
(peroxynitrous acid)
Trials
(peroxynitrous acid)
Recent Studies (post-2010)
(peroxynitrous acid)
Studies
(propofol)
Trials
(propofol)
Recent Studies (post-2010) (propofol)
3,303211,23016,8275,1886,805

Protein Interaction Comparison

ProteinTaxonomyperoxynitrous acid (IC50)propofol (IC50)
Gamma-aminobutyric acid receptor subunit piRattus norvegicus (Norway rat)8.1667
Aldo-keto reductase family 1 member B1Rattus norvegicus (Norway rat)9.393
Polyunsaturated fatty acid lipoxygenase ALOX15Oryctolagus cuniculus (rabbit)7.596
Gamma-aminobutyric acid receptor subunit alpha-1Homo sapiens (human)8
Gamma-aminobutyric acid receptor subunit beta-1Rattus norvegicus (Norway rat)8.1667
Gamma-aminobutyric acid receptor subunit deltaRattus norvegicus (Norway rat)8.1667
Gamma-aminobutyric acid receptor subunit gamma-2Homo sapiens (human)8
Gamma-aminobutyric acid receptor subunit gamma-2Rattus norvegicus (Norway rat)8.1667
Gamma-aminobutyric acid receptor subunit alpha-5Rattus norvegicus (Norway rat)8.1667
Gamma-aminobutyric acid receptor subunit alpha-3Rattus norvegicus (Norway rat)8.1667
Prostaglandin G/H synthase 1Homo sapiens (human)3.832
Gamma-aminobutyric acid receptor subunit gamma-1Rattus norvegicus (Norway rat)8.1667
Gamma-aminobutyric acid receptor subunit alpha-2Rattus norvegicus (Norway rat)8.1667
Sodium-dependent noradrenaline transporter Homo sapiens (human)9.393
Sodium- and chloride-dependent GABA transporter 1Rattus norvegicus (Norway rat)8.3
Gamma-aminobutyric acid receptor subunit alpha-4Rattus norvegicus (Norway rat)8.1667
Gamma-aminobutyric acid receptor subunit beta-3Homo sapiens (human)8
Gamma-aminobutyric acid receptor subunit gamma-3Rattus norvegicus (Norway rat)8.1667
Gamma-aminobutyric acid receptor subunit alpha-6Rattus norvegicus (Norway rat)8.1667
Sodium- and chloride-dependent GABA transporter 2Rattus norvegicus (Norway rat)8.3
Sodium- and chloride-dependent GABA transporter 3Rattus norvegicus (Norway rat)8.3
5-hydroxytryptamine receptor 2BHomo sapiens (human)5.499
Sodium- and chloride-dependent betaine transporterRattus norvegicus (Norway rat)8.3
Gamma-aminobutyric acid receptor subunit alpha-1Rattus norvegicus (Norway rat)8.1667
Gamma-aminobutyric acid receptor subunit beta-3Rattus norvegicus (Norway rat)8.1667
Gamma-aminobutyric acid receptor subunit beta-2Rattus norvegicus (Norway rat)8.1667
GABA theta subunitRattus norvegicus (Norway rat)8.1667
Gamma-aminobutyric acid receptor subunit epsilonRattus norvegicus (Norway rat)8.1667

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's5 (83.33)29.6817
2010's1 (16.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Deby, CM; Deby-Dupont, GP; Hans, P; Kohnen, SL; Lamy, ML; Mouithys-Mickalad, AA; Noels, AF1
Acquaviva, R; Avola, R; Barcellona, ML; Campisi, A; Li Volti, G; Mangiameli, S; Murabito, P; Musumeci, I; Raciti, G; Vanella, A1
Mikawa, K; Nishina, K; Obara, H; Takao, Y1
Deby, C; Deby-Dupont, G; Halusiak, E; Hans, P; Kohnen, S; Lamy, M; Mouithys-Mickalad, A; Noels, AF1
Acquaviva, R; Avola, R; Barcellona, ML; Campisi, A; Li Volti, G; Raciti, G; Vanella, L1
Chen, J; Tan, Z; Wang, J; Zhu, M1

Other Studies

6 other study(ies) available for peroxynitrous acid and propofol

ArticleYear
Investigation of the reaction of peroxynitrite with propofol at acid pH: predominant production of oxidized, nitrated, and halogenated derivatives.
    Nitric oxide : biology and chemistry, 2003, Volume: 8, Issue:3

    Topics: Anesthetics, Intravenous; Central Nervous System; Free Radicals; Halogens; Humans; Hydrogen-Ion Concentration; Nitrogen Oxides; Oxidation-Reduction; Peroxynitrous Acid; Propofol

2003
Propofol attenuates peroxynitrite-mediated DNA damage and apoptosis in cultured astrocytes: an alternative protective mechanism.
    Anesthesiology, 2004, Volume: 101, Issue:6

    Topics: Anesthetics, Intravenous; Animals; Apoptosis; Astrocytes; Blotting, Western; Caspase 3; Caspases; Cells, Cultured; Comet Assay; DNA; DNA Damage; Enzyme Activation; Heme Oxygenase (Decyclizing); Heme Oxygenase-1; L-Lactate Dehydrogenase; Molsidomine; Oxidative Stress; Peroxynitrous Acid; Propofol; Rats; Rats, Wistar; Tetrazolium Salts; Thiazoles

2004
Attenuation of acute lung injury with propofol in endotoxemia.
    Anesthesia and analgesia, 2005, Volume: 100, Issue:3

    Topics: Animals; Blood Pressure; Endotoxemia; Lung; Male; Nitric Oxide Synthase; Peroxynitrous Acid; Propofol; Rabbits; Respiratory Distress Syndrome; RNA, Messenger

2005
Catalytic activation of copper (II) salts on the reaction of peroxynitrite with propofol in alkaline medium.
    Nitric oxide : biology and chemistry, 2005, Volume: 12, Issue:4

    Topics: Alkalies; Bicarbonates; Carbon Dioxide; Catalysis; Copper; Electron Spin Resonance Spectroscopy; Hydrogen-Ion Concentration; Molecular Structure; Nitrogen; Nitrogen Dioxide; Oxygen; Peroxynitrous Acid; Propofol; Salts; Solutions; Temperature

2005
Propofol inhibits caspase-3 in astroglial cells: role of heme oxygenase-1.
    Current neurovascular research, 2005, Volume: 2, Issue:2

    Topics: Animals; Antioxidants; Astrocytes; Blotting, Western; Caspase 3; Caspase Inhibitors; Caspases; Cell Survival; Cells, Cultured; Enzyme Activation; Heme Oxygenase (Decyclizing); Heme Oxygenase-1; Molsidomine; Nitric Oxide Donors; Peroxynitrous Acid; Propofol; Rats; Rats, Wistar

2005
Propofol protects against high glucose-induced endothelial dysfunction in human umbilical vein endothelial cells.
    Anesthesia and analgesia, 2012, Volume: 114, Issue:2

    Topics: Anesthetics, Intravenous; Antioxidants; Biopterins; Blotting, Western; Cells, Cultured; Chromatography, Liquid; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Inhibitors; Glucose; GTP Cyclohydrolase; Human Umbilical Vein Endothelial Cells; Humans; Hyperglycemia; Mass Spectrometry; Nitric Oxide; Nitric Oxide Synthase Type III; Oxidative Stress; Peroxynitrous Acid; Phosphorylation; Propofol; Protein Multimerization; Superoxides; Time Factors

2012