Compounds > peroxynitrous acid
Page last updated: 2024-09-03

peroxynitrous acid and ouabain

peroxynitrous acid has been researched along with ouabain in 2 studies

Compound Research Comparison

Studies
(peroxynitrous acid)		Trials
(peroxynitrous acid)		Recent Studies (post-2010)
(peroxynitrous acid)		Studies
(ouabain)		Trials
(ouabain)		Recent Studies (post-2010) (ouabain)
3,303211,23016,35772747

Protein Interaction Comparison

ProteinTaxonomyperoxynitrous acid (IC50)ouabain (IC50)
STAT3, partialHomo sapiens (human)1.154
Kruppel-like factor 5Homo sapiens (human)0.0832
Sodium/potassium-transporting ATPase subunit alpha-1 Homo sapiens (human)6
Sodium/potassium-transporting ATPase subunit beta-1Homo sapiens (human)6
Sodium/potassium-transporting ATPase subunit alpha-1 Rattus norvegicus (Norway rat)4.3
Sodium/potassium-transporting ATPase subunit alpha-2Rattus norvegicus (Norway rat)0.17
Sodium/potassium-transporting ATPase subunit alpha-3 Rattus norvegicus (Norway rat)0.031
Sodium/potassium-transporting ATPase subunit beta-1 Rattus norvegicus (Norway rat)1.1263
Muscarinic acetylcholine receptor M1Rattus norvegicus (Norway rat)0.1646
Replicase polyprotein 1abSevere acute respiratory syndrome coronavirus 20.097
Sodium/potassium-transporting ATPase subunit alpha-3Homo sapiens (human)6
Sodium/potassium-transporting ATPase subunit beta-2Homo sapiens (human)6
Sodium/potassium-transporting ATPase subunit alpha-2Homo sapiens (human)6
Sodium/potassium-transporting ATPase subunit beta-3Homo sapiens (human)6
Sodium/potassium-transporting ATPase subunit gammaHomo sapiens (human)6
Potassium voltage-gated channel subfamily H member 2Homo sapiens (human)5.8
Sodium/potassium-transporting ATPase subunit alpha-4Homo sapiens (human)6
Sodium/potassium-transporting ATPase subunit beta-3Rattus norvegicus (Norway rat)0.0018
Sodium/potassium-transporting ATPase subunit alpha-4Rattus norvegicus (Norway rat)0.0031

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (50.00)29.6817
2010's1 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Arnett, KL; Gatto, C; Milanick, MA; Reifenberger, MS1
Gan, XT; Huang, C; Hunter, JC; Javadov, S; Karmazyn, M; Rajapurohitam, V; Xue, J1

Other Studies

2 other study(ies) available for peroxynitrous acid and ouabain

ArticleYear
The reactive nitrogen species peroxynitrite is a potent inhibitor of renal Na-K-ATPase activity.
    American journal of physiology. Renal physiology, 2008, Volume: 295, Issue:4

    Topics: Animals; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; In Vitro Techniques; Kidney; Ouabain; Peroxynitrous Acid; Protein Conformation; Sodium-Potassium-Exchanging ATPase; Tyrosine

2008
Ouabain increases iNOS-dependent nitric oxide generation which contributes to the hypertrophic effect of the glycoside: possible role of peroxynitrite formation.
    Molecular and cellular biochemistry, 2012, Volume: 363, Issue:1-2

    Topics: Animals; Cardiotonic Agents; Cell Shape; Cells, Cultured; Dose-Response Relationship, Drug; Enzyme Induction; Enzyme Inhibitors; Extracellular Signal-Regulated MAP Kinases; Hypertrophy, Left Ventricular; L-Lactate Dehydrogenase; Male; Myocytes, Cardiac; Nitric Oxide; Nitric Oxide Synthase Type II; Ouabain; p38 Mitogen-Activated Protein Kinases; Peroxynitrous Acid; Phosphorylation; Rats; Rats, Sprague-Dawley; RNA, Messenger; Signal Transduction; Superoxides; Time Factors; Tyrosine; Up-Regulation

2012