Compounds > peroxynitrous acid
Page last updated: 2024-09-03

peroxynitrous acid and nifedipine

peroxynitrous acid has been researched along with nifedipine in 4 studies

Compound Research Comparison

Studies
(peroxynitrous acid)		Trials
(peroxynitrous acid)		Recent Studies (post-2010)
(peroxynitrous acid)		Studies
(nifedipine)		Trials
(nifedipine)		Recent Studies (post-2010) (nifedipine)
3,303211,23016,0242,4961,505

Protein Interaction Comparison

ProteinTaxonomyperoxynitrous acid (IC50)nifedipine (IC50)
perilipin-5Homo sapiens (human)7.133
perilipin-1Homo sapiens (human)9.619
1-acylglycerol-3-phosphate O-acyltransferase ABHD5 isoform aHomo sapiens (human)8.376
Voltage-dependent L-type calcium channel subunit alpha-1CCavia porcellus (domestic guinea pig)0.0429
Voltage-dependent L-type calcium channel subunit alpha-1FHomo sapiens (human)0.035
Cytochrome P450 1A2Homo sapiens (human)0.3
Cytochrome P450 3A4Homo sapiens (human)10
Adenosine receptor A3Homo sapiens (human)7.214
Cytochrome P450 2C9 Homo sapiens (human)3.06
5-hydroxytryptamine receptor 2ARattus norvegicus (Norway rat)10
Alpha-1B adrenergic receptorRattus norvegicus (Norway rat)7.214
Voltage-dependent L-type calcium channel subunit alpha-1CRattus norvegicus (Norway rat)0.0385
Potassium voltage-gated channel subfamily A member 5Homo sapiens (human)6.1
3-oxo-5-alpha-steroid 4-dehydrogenase 1 Rattus norvegicus (Norway rat)1.12
Adenosine receptor A1Homo sapiens (human)7.701
3-oxo-5-alpha-steroid 4-dehydrogenase 2Rattus norvegicus (Norway rat)1.12
C-C chemokine receptor type 2Homo sapiens (human)2.191
Alpha-1A adrenergic receptorRattus norvegicus (Norway rat)7.214
Cytochrome P450 2J2Homo sapiens (human)3.06
Voltage-dependent L-type calcium channel subunit alpha-1D Homo sapiens (human)0.4733
Voltage-dependent L-type calcium channel subunit alpha-1CMus musculus (house mouse)1.2
Voltage-dependent L-type calcium channel subunit alpha-1SMus musculus (house mouse)1.2
Voltage-dependent L-type calcium channel subunit alpha-1SHomo sapiens (human)0.035
Voltage-dependent L-type calcium channel subunit alpha-1CHomo sapiens (human)0.0394
Myosin light chain kinase, smooth muscleHomo sapiens (human)2.02
Potassium channel subfamily K member 2 Bos taurus (cattle)8.2
Indoleamine 2,3-dioxygenase 2Mus musculus (house mouse)1.5
Voltage-dependent L-type calcium channel subunit alpha-1DMus musculus (house mouse)1.2
Voltage-dependent L-type calcium channel subunit alpha-1FMus musculus (house mouse)1.2

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (75.00)29.6817
2010's1 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Mak, IT; Weglicki, WB; Zhang, J1
Huang, XL; Pan, BX; Zhao, GL; Zhao, KS2
Aureliano, M; Gutierrez-Merino, C; Marques-da-Silva, D; Samhan-Arias, AK; Tiago, T1

Other Studies

4 other study(ies) available for peroxynitrous acid and nifedipine

ArticleYear
Protective effects of dihydropyridine Ca-blockers against endothelial cell oxidative injury due to combined nitric oxide and superoxide.
    Pharmacological research, 2002, Volume: 45, Issue:1

    Topics: Animals; Calcium Channel Blockers; Calcium Channels, L-Type; Cattle; Cell Survival; Cells, Cultured; Chromans; Dose-Response Relationship, Drug; Endothelium, Vascular; Glutathione; Lipid Peroxidation; Molsidomine; Nicardipine; Nifedipine; Nisoldipine; Nitric Oxide; Oxidative Stress; Peroxynitrous Acid; Superoxides; Thiobarbituric Acid Reactive Substances

2002
Mobilization of intracellular calcium by peroxynitrite in arteriolar smooth muscle cells from rats.
    Redox report : communications in free radical research, 2004, Volume: 9, Issue:1

    Topics: Animals; Arterioles; Calcium; Calcium Channel Blockers; Cells, Cultured; Dose-Response Relationship, Drug; Myocytes, Smooth Muscle; Nifedipine; Peroxynitrous Acid; Rats; Rats, Wistar; Ryanodine; Time Factors

2004
Calcium mobilization is required for peroxynitrite-mediated enhancement of spontaneous transient outward currents in arteriolar smooth muscle cells.
    Free radical biology & medicine, 2004, Sep-15, Volume: 37, Issue:6

    Topics: Animals; Boron Compounds; Caffeine; Calcium; Cells, Cultured; Dose-Response Relationship, Drug; Electrophysiology; Female; Male; Membrane Potentials; Models, Biological; Molsidomine; Muscle, Smooth; Myocytes, Smooth Muscle; Nifedipine; Patch-Clamp Techniques; Peroxynitrous Acid; Potassium; Rats; Rats, Wistar; Ryanodine; Signal Transduction; Time Factors

2004
Early disruption of the actin cytoskeleton in cultured cerebellar granule neurons exposed to 3-morpholinosydnonimine-oxidative stress is linked to alterations of the cytosolic calcium concentration.
    Cell calcium, 2011, Volume: 49, Issue:3

    Topics: Actin Cytoskeleton; Animals; Calcium; Calcium Channel Agonists; Calcium Channels, L-Type; Cells, Cultured; Cerebellum; Molsidomine; Neurons; Nifedipine; Oxidative Stress; Peroxynitrous Acid; Pyrroles; Rats; Rats, Wistar

2011