Page last updated: 2024-09-03

peroxynitrous acid and ng-nitroarginine methyl ester

peroxynitrous acid has been researched along with ng-nitroarginine methyl ester in 68 studies

Compound Research Comparison

Studies
(peroxynitrous acid)
Trials
(peroxynitrous acid)
Recent Studies (post-2010)
(peroxynitrous acid)
Studies
(ng-nitroarginine methyl ester)
Trials
(ng-nitroarginine methyl ester)
Recent Studies (post-2010) (ng-nitroarginine methyl ester)
3,303211,23012,6401172,342

Protein Interaction Comparison

ProteinTaxonomyperoxynitrous acid (IC50)ng-nitroarginine methyl ester (IC50)
Neutrophil elastaseHomo sapiens (human)2.7
Nitric oxide synthase, endothelialHomo sapiens (human)2.1
Nitric oxide synthase, brainHomo sapiens (human)1.1167
Nitric oxide synthase, inducibleMus musculus (house mouse)2.6
Nitric oxide synthase, inducibleHomo sapiens (human)8
Collagenase 3Homo sapiens (human)2.7

Research

Studies (68)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's55 (80.88)29.6817
2010's13 (19.12)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bradley, NJ; Bruckdorfer, KR; Jacobs, M; Khan, J; Low, SY; Naseem, KM; Sabetkar, M1
Cantoni, O; Guidarelli, A; Palomba, L; Scovassi, AI1
Hirose, M; Kivilaakso, E; Kiviluoto, T; Mustonen, H; Puolakkainen, P; Ranta-Knuuttila, T; Rönty, M; Sato, N; Watanabe, S1
López-García, MP; Sanz-González, SM; Vernia, S1
Alonso, D; Bentura, ML; Castro-Blanco, S; Encinas, JM; Fernández, AP; Fernández-Vizarra, P; Richart, A; Rodrigo, J; Rodríguez, I; Ruíz-Cabello, J; Santacana, M; Serrano, J; Uttenthal, LO1
Dick, A; Gordon, S; Liversidge, J1
Chang, WC; Chen, HY; Gau, RJ; Hseu, YC; Liu, TZ; Lu, FJ; Wang, SY; Yang, HL1
Barrett, KE; Resta-Lenert, S1
An, J; Camara, AK; Chen, Q; Hogg, N; Novalija, E; Riess, ML; Stowe, DF; Varadarajan, SG1
Bagi, Z; Csiszar, A; Koller, A; Ungvari, Z1
Bauer, G; Heigold, S1
Laude, K; Richard, V; Thuillez, C1
Boileau, C; Dumond, H; Jouzeau, JY; Martel-Pelletier, J; Netter, P; Pacquelet, S; Pelletier, JP; Presle, N; Terlain, B1
Favre, J; Laude, K; Richard, V; Thuillez, C1
Chang, HH; Jiang, M; Laniado-Schwartzman, M; Nasjletti, A; Wang, J; Wang, MH; Zand, BA1
Abou-Mohamed, G; Behzadian, MA; Caldwell, RB; Caldwell, RW; El-Remessy, AB; Franklin, T1
Iho, S; Iwasaki, H; Kobayashi, C; Muramatsu, I; Nakamura, K; Nakao, K; Sasaki, Y; Takahashi, T; Takauji, R; Tanaka, Y1
Abou-Mohamed, G; Caldwell, RB; Caldwell, RW; El-Remessy, AB; Green, K; Khalil, IE; Liou, GI; Matragoon, S; Roon, P; Tsai, NJ1
Kanzýk, Y; Tecder-Unal, M1
Morgan, DL; Shines, CJ1
Camara, AK; Kevin, LG; Novalija, E; Riess, ML; Stowe, DF1
Bezerra, MM; Brain, SD; da Rocha, FA; de Melo, LB; Greenacre, S; Jerônimo, SM; Keeble, J1
Anesetti, G; Barbeito, L; Beckman, JS; Cassina, P; Castellanos, R; Martinez-Palma, L; Pehar, M; Peluffo, H1
Chopin, C; Depontieu, F; Lancel, S; Marechal, X; Mordon, S; Neviere, R; Scherpereel, A; Tissier, S1
Darvesh, AS; Gudelsky, GA; Yamamoto, BK1
Ambrósio, AF; Araújo, IM; Carvalho, CM; Verdasca, MJ1
Chang, T; Wang, R; Wu, L1
Alonso-Orgaz, S; Barrientos, A; Carrasco-Martín, C; De la Pinta, JC; García-Méndez, A; González, MM; López-Farré, AJ; Macaya, C; Marques, M; Mateos-Cáceres, PJ; Porres, JC; Rico, LA1
Bubolz, AH; Gutterman, DD; Liu, Y; Newman, DK; Newman, PJ; Shi, Y1
Ding, W; Hudson, LG; Liu, KJ1
Antico Arciuch, VG; Carreras, MC; Franco, MC; Galli, S; Levisman, D; López, LM; Peralta, JG; Poderoso, JJ; Romorini, L1
Chang, KH; Jeon, EJ; Lee, SK; Park, SN; Park, YS; Yeo, SW1
Adachi, T; Clavreul, N; Cohen, RA; Ido, Y; Pimental, DR; Schöneich, C1
Hotter, G; Sola, A; Viñas, JL1
Delamere, NA; Shahidullah, M1
Beall, HD; Bunderson, M; Coffin, JD; Pereira, F; Schneider, MC; Shaw, PK1
Bae, N; Egea, M; Estévez, AG; Lange, PS; Ratan, RR; Sahawneh, MA1
Chang, T; Meng, QH; Wang, H; Wu, L1
Kamikawa, Y; Kojima, S; Ohno, Y; Sasaki, K; Sunagawa, M; Uchida, K1
Carbonell, LF; Cuevas, S; Díaz, J; Fenoy, F; Hernández, I; Quesada, T; Salom, MG; Valero, F1
Angelos, MG; Aune, SE; Falk, JA; Kuppusamy, P; Kutala, VK1
Christopher, TA; Fan, Q; Gao, F; Goldstein, BJ; Li, R; Lopez, BL; Ma, XL; Tao, L; Wang, WQ; Yang, X; Zhang, H1
Cuzzocrea, S; Esposito, E; Fabrizi, F; Masini, E; Matuschak, GM; Mollace, V; Muscoli, C; Ndengele, MM; Porreca, F; Salvemini, D1
Fukuhara, M; Ikeda, T; Komori, A; Oku, H; Okuno, T; Sugiyama, T1
Baber, SR; Bivalacqua, TJ; Champion, HC; Kadowitz, PJ; Nossaman, BD1
Fujii, M; Kohno, S; Mizutani, N; Nabe, T; Yoshino, S1
Bhatnagar, A; Kaiserova, K; Srivastava, S; Tang, XL1
Chen, SC; Chen, WC1
Dong, DL; Wang, WH; Yang, BF; Yue, P1
Kadowitz, PJ; Majid, DS; Matavelli, LC; Navar, LG1
de Lamirande, E; Lamothe, G1
Gryglewski, R; Hassan, M; Heeba, G; Khalifa, M; Malinski, T; Moselhy, ME1
Bos, IS; Bossenga, BE; Maarsingh, H; Meurs, H; Volders, HH; Zaagsma, J1
Bravo-San Pedro, JM; Fuentes, JM; González-Polo, RA; Morán, JM; Niso-Santano, M; Ortiz-Ortiz, MA; Soler, G1
Davidge, ST; Sankaralingam, S; Xu, H1
Chung, JM; Chung, K; Kim, HY; Lu, Y; Wang, J1
Berson, A; Fromenty, B; Huang, TT; Larosche, I; Lettéron, P; Mansouri, A; Moreau, R; Pessayre, D1
Cantoni, O; Cerioni, L; Palomba, L1
Chen, Z; Doyle, T; Finley, A; Salvemini, D1
Apostolova, N; Garcia-Bou, R; Herance, R; Hernandez-Mijares, A; Rocha, M; Victor, VM1
Camara, AK; Gadicherla, AK; Kwok, WM; Stowe, DF; Wakim, BT; Yang, M; Zhou, Y1
Fort, PE; Green, KM; Nagaraj, RH; Nahomi, RB; Palmer, A1
Aykin-Burns, N; Krager, KJ; Macmillan-Crow, LA; Marine, A1
Chen, SH; Hong, JS; Kadiiska, MB; Kalyanaraman, B; Kumar, A; Mason, RP; Zielonka, J1
Balfagón, G; Blanco-Rivero, J; Callejo, M; Caracuel, L; Sastre, E; Xavier, FE1
Eder, C; Miralles, F; Schilling, T; Spencer, NG1
Choi, EK; Jee, DL; Jung, H; Kim, S; Kwak, KH; Lim, DG; Lim, JA; Park, JM; Park, SH; Yi, SJ1
Alvarez-Olmedo, DG; Batulan, Z; Biaggio, VS; Ciocca, DR; Fanelli, MA; Gómez, NN; Koumbadinga, GA; O'Brien, ER; Shi, C1

Other Studies

68 other study(ies) available for peroxynitrous acid and ng-nitroarginine methyl ester

ArticleYear
The nitration of platelet cytosolic proteins during agonist-induced activation of platelets.
    FEBS letters, 2000, May-04, Volume: 473, Issue:1

    Topics: Aspirin; Blood Platelets; Blood Proteins; Blotting, Western; Cell Adhesion Molecules; Collagen; Cyclooxygenase Inhibitors; Cytosol; Enzyme-Linked Immunosorbent Assay; Humans; Membrane Proteins; Microfilament Proteins; Molecular Weight; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide Synthase; Nitrous Acid; Oxidants; Peroxynitrous Acid; Phosphoproteins; Platelet Activation; Thrombin; Tyrosine

2000
Different effects of tert-butylhydroperoxide-induced peroxynitrite-dependent and -independent DNA single-strand breakage on PC12 cell poly(ADP-ribose) polymerase activity.
    European journal of biochemistry, 2001, Volume: 268, Issue:20

    Topics: Animals; Benzamides; Cattle; CHO Cells; Cricetinae; DNA Damage; DNA Repair; DNA, Single-Stranded; Enzyme Activation; Humans; NAD; NG-Nitroarginine Methyl Ester; PC12 Cells; Peroxynitrous Acid; Poly(ADP-ribose) Polymerases; Rats; tert-Butylhydroperoxide; Time Factors; U937 Cells

2001
Nitric oxide donors retard wound healing in cultured rabbit gastric epithelial cell monolayers.
    American journal of physiology. Gastrointestinal and liver physiology, 2001, Volume: 281, Issue:5

    Topics: Animals; Cells, Cultured; Ditiocarb; Enzyme Inhibitors; Free Radical Scavengers; Gastric Mucosa; Male; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide Donors; Nitric Oxide Synthase; Nitrites; Nitroprusside; Peroxynitrous Acid; Pyrogallol; Rabbits; Wound Healing

2001
Involvement of peroxynitrite on the early loss of p450 in short-term hepatocyte cultures.
    Advances in experimental medicine and biology, 2001, Volume: 500

    Topics: Animals; Cells, Cultured; Cytochrome P-450 Enzyme System; Enzyme Inhibitors; Hepatocytes; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Peroxynitrous Acid; Rats; Rats, Sprague-Dawley; Time Factors

2001
Effects of oxygen and glucose deprivation on the expression and distribution of neuronal and inducible nitric oxide synthases and on protein nitration in rat cerebral cortex.
    The Journal of comparative neurology, 2002, Feb-04, Volume: 443, Issue:2

    Topics: Animals; Blotting, Western; Brain Ischemia; Calcium; Cerebral Cortex; Disease Models, Animal; Enzyme Inhibitors; Gene Expression; Glucose; Hypoxia; Immunohistochemistry; Magnetic Resonance Imaging; Male; Neurons; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Peroxynitrous Acid; Rats; Rats, Wistar; Reperfusion Injury; Tyrosine

2002
Nitric oxide mediates apoptosis through formation of peroxynitrite and Fas/Fas-ligand interactions in experimental autoimmune uveitis.
    The American journal of pathology, 2002, Volume: 160, Issue:3

    Topics: Animals; Apoptosis; Autoimmunity; Enzyme Inhibitors; Fas Ligand Protein; fas Receptor; Male; Membrane Glycoproteins; NG-Nitroarginine Methyl Ester; Nitric Oxide; Peroxynitrous Acid; Rats; Rats, Inbred Lew; Uveitis

2002
Humic acid induces the generation of nitric oxide in human umbilical vein endothelial cells: stimulation of nitric oxide synthase during cell injury.
    Free radical biology & medicine, 2002, Apr-01, Volume: 32, Issue:7

    Topics: Antioxidants; Ascorbic Acid; Blotting, Western; Calcium; Carrier Proteins; Cell Death; Cells, Cultured; Chelating Agents; Dexamethasone; DNA; DNA Fragmentation; Dose-Response Relationship, Drug; Egtazic Acid; Endothelium, Vascular; Enzyme Inhibitors; Humans; Humic Substances; L-Lactate Dehydrogenase; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; Peroxynitrous Acid; Protein Kinase C; Superoxide Dismutase; Ubiquitin-Protein Ligases; Vitamin E

2002
Enteroinvasive bacteria alter barrier and transport properties of human intestinal epithelium: role of iNOS and COX-2.
    Gastroenterology, 2002, Volume: 122, Issue:4

    Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Biological Transport; Caco-2 Cells; Chlorides; Cyclic AMP; Cyclic GMP; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Cystic Fibrosis Transmembrane Conductance Regulator; Diarrhea; Dinoprostone; Electric Impedance; Enzyme Inhibitors; Epithelial Cells; Escherichia coli Infections; Gene Expression Regulation, Enzymologic; Guanylate Cyclase; HT29 Cells; Humans; Intestinal Mucosa; Isoenzymes; Membrane Proteins; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrobenzenes; Peroxynitrous Acid; Prostaglandin-Endoperoxide Synthases; Salmonella Infections; Sodium-Potassium-Chloride Symporters; Solute Carrier Family 12, Member 2; Sulfonamides; Up-Regulation; Water-Electrolyte Balance

2002
Anesthetic preconditioning: triggering role of reactive oxygen and nitrogen species in isolated hearts.
    American journal of physiology. Heart and circulatory physiology, 2002, Volume: 283, Issue:1

    Topics: Anesthetics; Animals; Coronary Circulation; Enzyme Inhibitors; Guinea Pigs; Heart; In Vitro Techniques; Ischemic Preconditioning, Myocardial; Methyl Ethers; Myocardial Ischemia; Myocardial Reperfusion; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide; Peroxynitrous Acid; Reactive Oxygen Species; Reperfusion Injury; Sevoflurane; Time Factors; Tyrosine

2002
Impaired nitric oxide-mediated flow-induced coronary dilation in hyperhomocysteinemia: morphological and functional evidence for increased peroxynitrite formation.
    The American journal of pathology, 2002, Volume: 161, Issue:1

    Topics: Animals; Blotting, Western; Coronary Circulation; Coronary Vessels; Enzyme Inhibitors; Hyperhomocysteinemia; Immunohistochemistry; In Vitro Techniques; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Peroxynitrous Acid; Rats; Rats, Wistar; Superoxides; Tyrosine; Vasodilation

2002
RAW 264.7 macrophages induce apoptosis selectively in transformed fibroblasts: intercellular signaling based on reactive oxygen and nitrogen species.
    Journal of leukocyte biology, 2002, Volume: 72, Issue:3

    Topics: Aniline Compounds; Animals; Apoptosis; Cell Communication; Cell Line, Transformed; Cell Transformation, Viral; Coculture Techniques; Fibroblasts; Genes, src; Hydrogen Peroxide; Hypochlorous Acid; Immunologic Surveillance; Kidney; Macrophages; Metalloporphyrins; Mice; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; omega-N-Methylarginine; Peroxynitrous Acid; Phthalic Acids; Rats; Reactive Oxygen Species; Signal Transduction; Superoxides; Taurine; Transforming Growth Factor beta; Transforming Growth Factor beta1

2002
Peroxynitrite triggers a delayed resistance of coronary endothelial cells against ischemia-reperfusion injury.
    American journal of physiology. Heart and circulatory physiology, 2002, Volume: 283, Issue:4

    Topics: Acetylcholine; Animals; Coronary Vessels; Endothelium, Vascular; Enzyme Inhibitors; Free Radical Scavengers; Free Radicals; Ischemic Preconditioning, Myocardial; Male; Methionine; Molsidomine; Myocardial Reperfusion Injury; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Penicillamine; Peroxynitrous Acid; Rats; Rats, Wistar; Selenomethionine; Uric Acid

2002
Interleukin 17, a nitric oxide-producing cytokine with a peroxynitrite-independent inhibitory effect on proteoglycan synthesis.
    The Journal of rheumatology, 2002, Volume: 29, Issue:12

    Topics: Animals; Cartilage, Articular; Cells, Cultured; Chondrocytes; Dose-Response Relationship, Drug; Drug Combinations; Hindlimb; Injections, Intra-Articular; Interleukin-1; Interleukin-17; Joints; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Peroxynitrous Acid; Proteoglycans; Rats; Rats, Wistar; Recombinant Proteins; RNA, Messenger; Salicylates

2002
NO produced by endothelial NO synthase is a mediator of delayed preconditioning-induced endothelial protection.
    American journal of physiology. Heart and circulatory physiology, 2003, Volume: 284, Issue:6

    Topics: Acetylcholine; Animals; Blood Pressure; Blood Vessels; Coronary Vessels; Endothelium, Vascular; Free Radical Scavengers; Heart Rate; In Vitro Techniques; Indazoles; Ischemic Preconditioning, Myocardial; Male; Muscle Relaxation; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Nitroprusside; Peroxynitrous Acid; Rats; Rats, Wistar; Selenomethionine; Vasodilator Agents

2003
Regulation of renal CYP4A expression and 20-HETE synthesis by nitric oxide in pregnant rats.
    American journal of physiology. Renal physiology, 2003, Volume: 285, Issue:2

    Topics: Animals; Baculoviridae; Blood Pressure; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Cytochrome P450 Family 4; Enzyme Inhibitors; Female; Gene Expression Regulation, Enzymologic; Hydroxyeicosatetraenoic Acids; Kidney; Male; Microcirculation; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitroprusside; Peroxynitrous Acid; Pregnancy; Pregnancy, Animal; Rats; Rats, Sprague-Dawley; Recombinant Proteins

2003
Experimental diabetes causes breakdown of the blood-retina barrier by a mechanism involving tyrosine nitration and increases in expression of vascular endothelial growth factor and urokinase plasminogen activator receptor.
    The American journal of pathology, 2003, Volume: 162, Issue:6

    Topics: Animals; Blood-Retinal Barrier; Body Weight; Diabetes Mellitus, Experimental; Endothelial Growth Factors; Enzyme Inhibitors; Gene Expression; Intercellular Signaling Peptides and Proteins; Lipid Peroxidation; Lymphokines; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide Synthase; Nitrites; Oxidative Stress; Peroxynitrous Acid; Rats; Rats, Sprague-Dawley; Reactive Nitrogen Species; Receptors, Cell Surface; Receptors, Urokinase Plasminogen Activator; Retina; RNA, Messenger; Tyrosine; Uric Acid; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors

2003
Nicotine induces human neutrophils to produce IL-8 through the generation of peroxynitrite and subsequent activation of NF-kappaB.
    Journal of leukocyte biology, 2003, Volume: 74, Issue:5

    Topics: Humans; I-kappa B Proteins; Interleukin-8; Kinetics; Neutrophils; NF-kappa B; NF-KappaB Inhibitor alpha; NG-Nitroarginine Methyl Ester; Nicotine; Nitric Oxide; Peroxidase; Peroxynitrous Acid; Protein Transport; Reactive Oxygen Species; Smoking; Tumor Necrosis Factor-alpha

2003
Neuroprotective effect of (-)Delta9-tetrahydrocannabinol and cannabidiol in N-methyl-D-aspartate-induced retinal neurotoxicity: involvement of peroxynitrite.
    The American journal of pathology, 2003, Volume: 163, Issue:5

    Topics: Animals; Apoptosis; Cannabidiol; Cyclic N-Oxides; Dose-Response Relationship, Drug; Dronabinol; In Situ Nick-End Labeling; Male; N-Methylaspartate; Neurons; Neuroprotective Agents; NG-Nitroarginine Methyl Ester; Oxidative Stress; Peroxynitrous Acid; Rats; Rats, Sprague-Dawley; Receptor, Cannabinoid, CB1; Retina; Reverse Transcriptase Polymerase Chain Reaction; Spin Labels; Time Factors

2003
Peroxynitrite in reperfusion arrhythmias and its whole blood chemiluminescence results.
    Pharmacological research, 2004, Volume: 49, Issue:1

    Topics: Animals; Blood Pressure; Catalase; Drug Administration Schedule; Drug Therapy, Combination; Enzyme Inhibitors; Free Radical Scavengers; Heart Rate; Infusions, Intravenous; Luminescent Measurements; Male; Myocardial Reperfusion Injury; N-Formylmethionine Leucyl-Phenylalanine; NG-Nitroarginine Methyl Ester; Peroxynitrous Acid; Rats; Rats, Wistar; Reactive Oxygen Species; Superoxide Dismutase; Tachycardia, Ventricular; Uric Acid; Ventricular Fibrillation; Vision, Ocular

2004
Alveolar macrophage cytotoxicity for normal lung fibroblasts is mediated by nitric oxide release.
    Toxicology in vitro : an international journal published in association with BIBRA, 2004, Volume: 18, Issue:1

    Topics: Animals; Cell Culture Techniques; Cell Survival; Coculture Techniques; Culture Media; Dose-Response Relationship, Drug; Drug Combinations; Drug Evaluation, Preclinical; Drug Synergism; Fibroblasts; Interferon-gamma; Interleukin-1; Lipopolysaccharides; Lung; Macrophages, Alveolar; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Peroxynitrous Acid; Rats; Rats, Sprague-Dawley; Superoxide Dismutase; Tumor Necrosis Factor-alpha; Tyrosine

2004
Hypothermia augments reactive oxygen species detected in the guinea pig isolated perfused heart.
    American journal of physiology. Heart and circulatory physiology, 2004, Volume: 286, Issue:4

    Topics: Animals; Electron Transport; Enzyme Inhibitors; Extracellular Space; Free Radical Scavengers; Guinea Pigs; Hypothermia; In Vitro Techniques; Mitochondria, Heart; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Peroxynitrous Acid; Reactive Oxygen Species; Superoxides; Ventricular Function, Left; Vitamin K 3

2004
Reactive nitrogen species scavenging, rather than nitric oxide inhibition, protects from articular cartilage damage in rat zymosan-induced arthritis.
    British journal of pharmacology, 2004, Volume: 141, Issue:1

    Topics: Animals; Arthritis, Experimental; Cartilage, Articular; Disease Models, Animal; Dose-Response Relationship, Drug; Free Radical Scavengers; Glycosaminoglycans; Guanidines; Injections, Intra-Articular; Injections, Intraperitoneal; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Peroxynitrous Acid; Rats; Rats, Wistar; Reactive Nitrogen Species; Synovial Fluid; Synovial Membrane; Synovitis; Tyrosine; Uric Acid; Zymosan

2004
Involvement of nitric oxide on kainate-induced toxicity in oligodendrocyte precursors.
    Neurotoxicity research, 2003, Volume: 5, Issue:6

    Topics: Animals; Animals, Newborn; Cell Count; Cell Death; Cells, Cultured; Culture Media; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Fluorescent Antibody Technique; Kainic Acid; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Oligodendroglia; Peroxynitrous Acid; Quinoxalines; Rats; Rats, Wistar; Spinal Cord; Stem Cells; Tyrosine

2003
Peroxynitrite decomposition catalysts prevent myocardial dysfunction and inflammation in endotoxemic rats.
    Journal of the American College of Cardiology, 2004, Jun-16, Volume: 43, Issue:12

    Topics: Animals; Biomarkers; Catalysis; Disease Models, Animal; Endothelium, Vascular; Endotoxemia; Enzyme Inhibitors; Fluorescent Dyes; Guanidines; I-kappa B Proteins; Leukocytes; Metalloporphyrins; Models, Cardiovascular; Myocarditis; NF-kappa B; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Peroxynitrous Acid; Rats; Rats, Sprague-Dawley; Tumor Necrosis Factor-alpha; Tyrosine; Xanthenes

2004
Evidence for the involvement of nitric oxide in 3,4-methylenedioxymethamphetamine-induced serotonin depletion in the rat brain.
    The Journal of pharmacology and experimental therapeutics, 2005, Volume: 312, Issue:2

    Topics: Animals; Brain Chemistry; Citrulline; Dopamine; Enzyme Inhibitors; Fever; Male; Malonates; Microdialysis; N-Methyl-3,4-methylenedioxyamphetamine; Neostriatum; Nerve Tissue Proteins; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Peroxynitrous Acid; Rats; Serotonin; Serotonin Agents; Thiourea; Tyrosine

2005
Nitric oxide inhibits complex I following AMPA receptor activation via peroxynitrite.
    Neuroreport, 2004, Sep-15, Volume: 15, Issue:13

    Topics: Analysis of Variance; Animals; Antihypertensive Agents; Benzothiadiazines; Cells, Cultured; Cyclic GMP; Drug Interactions; Embryo, Mammalian; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Hippocampus; Immunohistochemistry; Kainic Acid; Microtubule-Associated Proteins; Neurons; NG-Nitroarginine Methyl Ester; Nitric Oxide; Peroxynitrous Acid; Proton Pumps; Quinoxalines; Rats; Receptors, AMPA; Tyrosine

2004
Methylglyoxal-induced nitric oxide and peroxynitrite production in vascular smooth muscle cells.
    Free radical biology & medicine, 2005, Jan-15, Volume: 38, Issue:2

    Topics: Animals; Aorta; Cell Line; Cells, Cultured; Dose-Response Relationship, Drug; Free Radicals; Glucose; Hydrogen Peroxide; Insulin Resistance; Models, Chemical; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; NG-Nitroarginine Methyl Ester; Nitric Oxide; Oxidative Stress; Oxygen; Peroxynitrous Acid; Pyruvaldehyde; Rats; Reactive Oxygen Species; Signal Transduction; Time Factors

2005
Endothelial hypoxic preconditioning in rat hypoxic isolated aortic segments.
    Experimental physiology, 2005, Volume: 90, Issue:4

    Topics: Acetylcholine; Animals; Aorta, Thoracic; Endothelium, Vascular; Enzyme Inhibitors; HSP90 Heat-Shock Proteins; Hypoxia; In Vitro Techniques; Ischemic Preconditioning; Isometric Contraction; Male; Muscle Relaxation; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Peroxynitrous Acid; Phenylephrine; Phosphorylation; Rats; Rats, Wistar; Serine; Superoxides; Vasoconstrictor Agents; Vasodilator Agents

2005
Peroxynitrite reduces the endothelium-derived hyperpolarizing factor component of coronary flow-mediated dilation in PECAM-1-knockout mice.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2006, Volume: 290, Issue:1

    Topics: Animals; Azoles; Biological Factors; Coronary Vessels; Gene Deletion; Hydrogen Peroxide; Indomethacin; Isoindoles; Male; Mice; Mice, Knockout; NG-Nitroarginine Methyl Ester; Nitric Oxide; Organoselenium Compounds; Peroxynitrous Acid; Platelet Endothelial Cell Adhesion Molecule-1; Prostaglandins; Tyrosine; Vasodilation

2006
Inorganic arsenic compounds cause oxidative damage to DNA and protein by inducing ROS and RNS generation in human keratinocytes.
    Molecular and cellular biochemistry, 2005, Volume: 279, Issue:1-2

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Arsenates; Arsenites; Cell Line; Chromatography, High Pressure Liquid; Deoxyguanosine; DNA Damage; Dose-Response Relationship, Drug; Enzyme Inhibitors; Free Radical Scavengers; Humans; Keratinocytes; Metalloporphyrins; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Peroxynitrous Acid; Reactive Nitrogen Species; Reactive Oxygen Species; Sodium Compounds; Superoxide Dismutase; Time Factors; Tyrosine

2005
Hypothyroid phenotype is contributed by mitochondrial complex I inactivation due to translocated neuronal nitric-oxide synthase.
    The Journal of biological chemistry, 2006, Feb-24, Volume: 281, Issue:8

    Topics: Animals; Cyclin D1; Cytosol; Electron Transport Complex I; Electrons; Electrophoresis, Polyacrylamide Gel; HSP90 Heat-Shock Proteins; Hypothyroidism; Immunoblotting; Immunoprecipitation; Liver; Male; MAP Kinase Signaling System; Microscopy, Immunoelectron; Mitochondria; Mitochondria, Liver; Models, Chemical; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Oxidants; Oxygen; p38 Mitogen-Activated Protein Kinases; Peroxynitrous Acid; Phenotype; Protein Isoforms; Protein Transport; Rats; Rats, Wistar; Reactive Oxygen Species; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Subcellular Fractions; Thyroid Hormones; Transcription, Genetic

2006
Effect of nitric oxide and peroxynitrite on mucociliary transport function of experimental otitis media.
    Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery, 2006, Volume: 134, Issue:1

    Topics: Animals; Disease Models, Animal; Free Radical Scavengers; Guinea Pigs; Lipopolysaccharides; Mucociliary Clearance; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Otitis Media with Effusion; Peroxynitrous Acid; Pseudomonas aeruginosa; Uric Acid

2006
S-glutathiolation by peroxynitrite of p21ras at cysteine-118 mediates its direct activation and downstream signaling in endothelial cells.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2006, Volume: 20, Issue:3

    Topics: Acetophenones; Androstadienes; Animals; Aorta; Butadienes; Cattle; Cells, Cultured; Cysteine; Endothelial Cells; Endothelium, Vascular; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Glutathione; Guanosine Diphosphate; Lipoproteins, LDL; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitriles; Oxidation-Reduction; Peroxynitrous Acid; Phosphorylation; Protein Processing, Post-Translational; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins p21(ras); Recombinant Fusion Proteins; Signal Transduction; Wortmannin

2006
Mitochondrial NOS upregulation during renal I/R causes apoptosis in a peroxynitrite-dependent manner.
    Kidney international, 2006, Volume: 69, Issue:8

    Topics: Animals; Apoptosis; Biomarkers; Blotting, Western; Cytochromes c; Densitometry; Enzyme Inhibitors; Ischemia; Kidney; Male; Mitochondria; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type I; Nitrites; Peroxynitrous Acid; Rats; Rats, Wistar; Reperfusion Injury; Reverse Transcriptase Polymerase Chain Reaction; Time Factors; Up-Regulation

2006
NO donors inhibit Na,K-ATPase activity by a protein kinase G-dependent mechanism in the nonpigmented ciliary epithelium of the porcine eye.
    British journal of pharmacology, 2006, Volume: 148, Issue:6

    Topics: Animals; Aqueous Humor; Arginine; Ciliary Body; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Enzyme Inhibitors; NG-Nitroarginine Methyl Ester; Nitric Oxide Donors; Nitrites; Peroxynitrous Acid; Sodium-Potassium-Exchanging ATPase; Swine

2006
Manganese enhances peroxynitrite and leukotriene E4 formation in bovine aortic endothelial cells exposed to arsenic.
    Cardiovascular toxicology, 2006, Volume: 6, Issue:1

    Topics: Animals; Aorta; Arsenic; Arsenites; Cattle; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Drug Combinations; Drug Synergism; Endothelium, Vascular; Environmental Pollutants; Enzyme Inhibitors; Leukotriene E4; Manganese; NG-Nitroarginine Methyl Ester; Peroxynitrous Acid; Sodium Compounds; Tyrosine

2006
Arginase 1 regulation of nitric oxide production is key to survival of trophic factor-deprived motor neurons.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2006, Aug-16, Volume: 26, Issue:33

    Topics: Animals; Apoptosis; Arginase; Arginine; Brain-Derived Neurotrophic Factor; Cell Survival; Cells, Cultured; Enzyme Inhibitors; Growth Substances; Motor Neurons; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Peroxynitrous Acid; Rats; Transfection

2006
Fructose-induced peroxynitrite production is mediated by methylglyoxal in vascular smooth muscle cells.
    Life sciences, 2006, Nov-25, Volume: 79, Issue:26

    Topics: Acetylcysteine; Animals; Cell Line; Dose-Response Relationship, Drug; Enzyme Inhibitors; Fructose; Glutathione; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Peroxynitrous Acid; Pyruvaldehyde; Superoxide Dismutase; Superoxides; Time Factors

2006
The suppressant effect of GEA3162 on spontaneous serotonin release from human colonic mucosa in vitro.
    European journal of pharmacology, 2006, Nov-21, Volume: 550, Issue:1-3

    Topics: Calcium Channel Blockers; Chromatography, High Pressure Liquid; Colon; Electrochemistry; Enzyme Inhibitors; Gastrointestinal Hormones; Guanylate Cyclase; Hydroxyindoleacetic Acid; Intestinal Mucosa; Natriuretic Peptides; NG-Nitroarginine Methyl Ester; Nicardipine; Nitric Oxide Donors; Nitric Oxide Synthase; Oxadiazoles; Peroxynitrous Acid; Quinoxalines; Serotonin; Triazoles

2006
N-acetylcysteine exerts protective effects and prevents lung redox imbalance and peroxynitrite generation in endotoxemic rats.
    Medicinal chemistry (Shariqah (United Arab Emirates)), 2007, Volume: 3, Issue:1

    Topics: Acetylcysteine; Animals; Coloring Agents; Endotoxemia; Enzyme Inhibitors; Free Radical Scavengers; Lactic Acid; Lipopolysaccharides; Lung; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Oxidation-Reduction; Peroxynitrous Acid; Platelet Count; Rats; Rats, Wistar; Rhodamines; Sulfhydryl Compounds; Thiobarbituric Acid Reactive Substances

2007
Inhibition of peroxynitrite precursors, NO and O2, at the onset of reperfusion improves myocardial recovery.
    Resuscitation, 2007, Volume: 74, Issue:3

    Topics: Animals; Disease Models, Animal; Enzyme Inhibitors; Free Radical Scavengers; Male; Molsidomine; Myocardial Contraction; Myocardial Reperfusion Injury; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide; Oxygen Consumption; Peroxynitrous Acid; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Recovery of Function; Sodium-Potassium-Exchanging ATPase; Superoxide Dismutase; Treatment Outcome; Ventricular Function, Left

2007
Adiponectin improves endothelial function in hyperlipidemic rats by reducing oxidative/nitrative stress and differential regulation of eNOS/iNOS activity.
    American journal of physiology. Endocrinology and metabolism, 2007, Volume: 293, Issue:6

    Topics: Acetylcholine; Adiponectin; Animals; Antioxidants; Aorta; Dietary Fats; Endothelium, Vascular; Hyperlipidemias; Lipids; Male; Membrane Glycoproteins; NADPH Oxidase 2; NADPH Oxidases; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Oxidative Stress; Peptide Fragments; Peroxynitrous Acid; Phosphorylation; Rats; Rats, Sprague-Dawley; S-Nitroso-N-Acetylpenicillamine; Superoxides; Vasodilation

2007
Therapeutic manipulation of peroxynitrite attenuates the development of opiate-induced antinociceptive tolerance in mice.
    The Journal of clinical investigation, 2007, Volume: 117, Issue:11

    Topics: Analgesics, Opioid; Animals; Cytokines; DNA Damage; Drug Tolerance; Enzyme Inhibitors; Free Radical Scavengers; Humans; Male; Metalloporphyrins; Mice; NG-Nitroarginine Methyl Ester; Pain; Pain Threshold; Peroxynitrous Acid; Poly(ADP-ribose) Polymerases; Porphyrins; Rats; Spinal Cord; Superoxide Dismutase; Tyrosine

2007
Endothelin-1 (ET-1) causes death of retinal neurons through activation of nitric oxide synthase (NOS) and production of superoxide anion.
    Experimental eye research, 2008, Volume: 86, Issue:1

    Topics: Amacrine Cells; Animals; Cell Death; Cells, Cultured; Dose-Response Relationship, Drug; Endothelin-1; Enzyme Activation; Enzyme Inhibitors; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Peroxynitrous Acid; Rats; Rats, Wistar; Receptor, Endothelin B; Retina; Superoxide Dismutase; Superoxides

2008
Analysis of vasodilator responses to peroxynitrite in the hindlimb vascular bed of the cat.
    Journal of cardiovascular pharmacology, 2007, Volume: 50, Issue:4

    Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Adamantane; Animals; Cats; Female; Hindlimb; Male; Meclofenamic Acid; Morpholines; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide Donors; Perfusion; Peroxynitrous Acid; Phosphodiesterase Inhibitors; Potassium Channel Blockers; Purinones; Regional Blood Flow; Rolipram; Sodium Nitrite; Splanchnic Circulation; Vascular Resistance; Vasoconstrictor Agents; Vasodilator Agents

2007
Involvement of peroxynitrite in pollen-induced nasal blockage in guinea pigs.
    European journal of pharmacology, 2008, Mar-17, Volume: 582, Issue:1-3

    Topics: Administration, Intranasal; Allergens; Allopurinol; Analysis of Variance; Animals; Antioxidants; Azoles; Cryptomeria; Disease Models, Animal; Guinea Pigs; Isoindoles; Leukotriene D4; Male; Nasal Obstruction; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Organoselenium Compounds; Peroxynitrous Acid; Pollen; Rhinitis, Allergic, Seasonal; Xanthine Oxidase

2008
Role of nitric oxide in regulating aldose reductase activation in the ischemic heart.
    The Journal of biological chemistry, 2008, Apr-04, Volume: 283, Issue:14

    Topics: Aldehyde Reductase; Animals; Bradykinin; Dithiothreitol; Enzyme Activation; Enzyme Inhibitors; Ferric Compounds; Glucose; Hesperidin; Hypoglycemic Agents; Imidazolidines; Insulin; Lipid Peroxidation; Male; Metalloporphyrins; Myocardial Reperfusion Injury; Myocardium; Naphthalenes; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Peroxynitrous Acid; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Rats; Signal Transduction; Sorbitol; Vasodilator Agents

2008
Vascular leakage induced by exposure to arsenic via increased production of NO, hydroxyl radical and peroxynitrite.
    Microvascular research, 2008, Volume: 75, Issue:3

    Topics: Animals; Arsenites; Blood Vessels; Capillary Permeability; Carbon; Dose-Response Relationship, Drug; Drug Therapy, Combination; Enzyme Inhibitors; Evans Blue; Free Radical Scavengers; Guanidines; Hydroxyl Radical; Injections, Intradermal; Injections, Intravenous; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Peroxynitrous Acid; Rats; Rats, Sprague-Dawley; Skin; Sodium Compounds; Thiourea; Tyrosine

2008
Hydrogen peroxide stimulates the Ca(2+)-activated big-conductance K channels (BK) through cGMP signaling pathway in cultured human endothelial cells.
    Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2008, Volume: 22, Issue:1-4

    Topics: Cells, Cultured; Cyclic GMP; Endothelial Cells; Humans; Hydrogen Peroxide; Ion Channel Gating; Large-Conductance Calcium-Activated Potassium Channels; Microscopy, Confocal; NG-Nitroarginine Methyl Ester; Peroxynitrous Acid

2008
Renal hemodynamic and excretory responses to intra-arterial infusion of peroxynitrite in anesthetized rats.
    American journal of physiology. Renal physiology, 2009, Volume: 296, Issue:1

    Topics: Animals; Dose-Response Relationship, Drug; Enzyme Inhibitors; Glomerular Filtration Rate; Infusions, Intra-Arterial; Kidney; Male; NG-Nitroarginine Methyl Ester; Peroxynitrous Acid; Rats; Rats, Sprague-Dawley; Regional Blood Flow; Unconsciousness; Vasoconstriction; Vasodilation

2009
Reactive oxygen-induced reactive oxygen formation during human sperm capacitation.
    Free radical biology & medicine, 2009, Feb-15, Volume: 46, Issue:4

    Topics: Acrosome Reaction; Animals; Arginine; Blood Proteins; Bucladesine; Cattle; Cell-Free System; Cells, Cultured; Female; Fetal Blood; Humans; Hydrazines; Infant, Newborn; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Peroxynitrous Acid; Phosphorylation; Pregnancy; Serum Albumin, Bovine; Sperm Capacitation; Spermatozoa; Superoxide Dismutase; Superoxides; Tyrosine

2009
Anti-atherogenic effect of statins: role of nitric oxide, peroxynitrite and haem oxygenase-1.
    British journal of pharmacology, 2009, Volume: 156, Issue:8

    Topics: Animals; Aorta; Arginine; Atherosclerosis; Atorvastatin; Disease Models, Animal; Endothelium, Vascular; Enzyme Inhibitors; Heme Oxygenase-1; Hemin; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lipid Peroxidation; Male; Malondialdehyde; Metalloporphyrins; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type III; Peroxynitrous Acid; Protoporphyrins; Pyrroles; Rabbits; Simvastatin; Time Factors

2009
L-arginine deficiency causes airway hyperresponsiveness after the late asthmatic reaction.
    The European respiratory journal, 2009, Volume: 34, Issue:1

    Topics: Animals; Arginase; Arginine; Asthma; Bronchial Hyperreactivity; Disease Models, Animal; Guinea Pigs; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type II; Ovalbumin; Perfusion; Peroxynitrous Acid; Polyamines; Polyelectrolytes; Trachea

2009
Nitric oxide-mediated toxicity in paraquat-exposed SH-SY5Y cells: a protective role of 7-nitroindazole.
    Neurotoxicity research, 2009, Volume: 16, Issue:2

    Topics: Apoptosis Regulatory Proteins; Cell Cycle Proteins; Cell Death; Cell Line, Tumor; DNA Damage; Dose-Response Relationship, Drug; Drug Interactions; Egtazic Acid; Enzyme Inhibitors; Flow Cytometry; Gene Expression Regulation, Neoplastic; Herbicides; Humans; Indazoles; NADPH Dehydrogenase; Neuroblastoma; Neuroprotective Agents; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Nuclear Proteins; Paraquat; Peroxynitrous Acid; Tetrazolium Salts; Thiazoles; Tumor Suppressor Protein p53

2009
Arginase contributes to endothelial cell oxidative stress in response to plasma from women with preeclampsia.
    Cardiovascular research, 2010, Jan-01, Volume: 85, Issue:1

    Topics: Arginase; Arginine; Biopterins; Endothelial Cells; Female; Humans; Molsidomine; NADPH Oxidases; NF-kappa B; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Oxidative Stress; Peroxynitrous Acid; Pre-Eclampsia; Pregnancy

2010
Superoxide signaling in pain is independent of nitric oxide signaling.
    Neuroreport, 2009, Oct-28, Volume: 20, Issue:16

    Topics: Animals; Antimycin A; Cyclic N-Oxides; Disease Models, Animal; Enzyme Inhibitors; Hyperalgesia; Male; Metalloporphyrins; Mice; Mice, Inbred C57BL; Neuralgia; Neuroprotective Agents; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitroso Compounds; Pain Measurement; Peroxynitrous Acid; Reactive Oxygen Species; Signal Transduction; Spin Labels; Superoxides; Tyrosine

2009
Hepatic mitochondrial DNA depletion after an alcohol binge in mice: probable role of peroxynitrite and modulation by manganese superoxide dismutase.
    The Journal of pharmacology and experimental therapeutics, 2010, Volume: 332, Issue:3

    Topics: Animals; Caspase 3; Cyclic N-Oxides; DNA-Binding Proteins; DNA, Mitochondrial; Electron Transport Complex I; Ethanol; Free Radical Scavengers; Glutathione Peroxidase; High Mobility Group Proteins; Iron; Liver; Mice; Mice, Knockout; Mitochondria, Liver; Mitochondrial Proton-Translocating ATPases; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type II; Peroxynitrous Acid; Reactive Oxygen Species; Spin Labels; Superoxide Dismutase; Transcription Factors; Uric Acid

2010
Arachidonic acid inhibits neuronal nitric oxide synthase elicited by proinflammatory stimuli and promotes astrocyte survival with both exogenous and endogenous peroxynitrite via different mechanisms.
    Journal of neuroscience research, 2010, Aug-15, Volume: 88, Issue:11

    Topics: Animals; Animals, Newborn; Arachidonic Acid; Astrocytes; Blotting, Western; Cell Survival; Cells, Cultured; Cerebral Cortex; Enzyme Inhibitors; Immunohistochemistry; Inflammation; Lipoxygenase; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type I; Peroxynitrous Acid; Protein Tyrosine Phosphatases; Rats; Rats, Sprague-Dawley; Signal Transduction; Tyrosine

2010
Role for peroxynitrite in sphingosine-1-phosphate-induced hyperalgesia in rats.
    Pain, 2011, Volume: 152, Issue:3

    Topics: Acetophenones; Anilides; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Activation; Enzyme Inhibitors; Hyperalgesia; Lysophospholipids; Male; Metalloporphyrins; NG-Nitroarginine Methyl Ester; Organophosphonates; Oxadiazoles; Peroxynitrous Acid; Rats; Rats, Sprague-Dawley; Reaction Time; Receptors, Lysosphingolipid; Sphingosine; Thiophenes; Time Factors

2011
Mitochondrial antioxidants alleviate oxidative and nitrosative stress in a cellular model of sepsis.
    Pharmaceutical research, 2011, Volume: 28, Issue:11

    Topics: Antioxidants; Endotoxins; Enzyme Inhibitors; Escherichia coli; Glutathione; Human Umbilical Vein Endothelial Cells; Humans; Mitochondria; Models, Biological; Molecular Targeted Therapy; NAD; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitrosation; Oxidative Stress; Oxygen; Peroxynitrous Acid; Reactive Oxygen Species; Sepsis

2011
Tyrosine nitration of voltage-dependent anion channels in cardiac ischemia-reperfusion: reduction by peroxynitrite scavenging.
    Biochimica et biophysica acta, 2012, Volume: 1817, Issue:11

    Topics: Animals; Guinea Pigs; Mass Spectrometry; Mitochondrial Proteins; Myocardial Reperfusion Injury; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide; Peroxynitrous Acid; Resveratrol; Stilbenes; Superoxides; Tyrosine; Voltage-Dependent Anion Channels

2012
Pro-inflammatory cytokines downregulate Hsp27 and cause apoptosis of human retinal capillary endothelial cells.
    Biochimica et biophysica acta, 2014, Volume: 1842, Issue:2

    Topics: Apoptosis; Blotting, Western; Cells, Cultured; Cytokines; Dose-Response Relationship, Drug; Down-Regulation; Endothelial Cells; Glucose; Heat-Shock Proteins; HSP27 Heat-Shock Proteins; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Inflammation Mediators; Interferon-gamma; Interleukin-1beta; Molecular Chaperones; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type II; Peroxynitrous Acid; Reactive Oxygen Species; Retina; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; Tryptophan; Tumor Necrosis Factor-alpha

2014
Peroxynitrite induced mitochondrial biogenesis following MnSOD knockdown in normal rat kidney (NRK) cells.
    Redox biology, 2014, Volume: 2

    Topics: Animals; Cell Line; DNA, Mitochondrial; Electron Transport Chain Complex Proteins; Gene Knockdown Techniques; Kidney; Mitochondria; Models, Biological; NG-Nitroarginine Methyl Ester; Organophosphorus Compounds; Peroxynitrous Acid; Rats; Reactive Oxygen Species; Superoxide Dismutase; Ubiquinone

2014
Inducible nitric oxide synthase is key to peroxynitrite-mediated, LPS-induced protein radical formation in murine microglial BV2 cells.
    Free radical biology & medicine, 2014, Volume: 73

    Topics: Acetophenones; Amidines; Animals; Antioxidants; Benzylamines; Boronic Acids; Cell Line, Transformed; Coumarins; Enzyme Inhibitors; Free Radicals; Imidazoles; Lipopolysaccharides; Metalloporphyrins; Mice; Microglia; Neurodegenerative Diseases; NF-kappa B; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type II; p38 Mitogen-Activated Protein Kinases; Peroxynitrous Acid; Proline; Pyridines; RNA Interference; RNA, Small Interfering; Spin Trapping; Thiocarbamates

2014
Biphasic Effect of Diabetes on Neuronal Nitric Oxide Release in Rat Mesenteric Arteries.
    PloS one, 2016, Volume: 11, Issue:6

    Topics: Animals; Diabetes Mellitus, Experimental; Electric Stimulation; Male; Mesenteric Arteries; NG-Nitroarginine Methyl Ester; Nitric Oxide; Peroxynitrous Acid; Rats; Streptozocin; Superoxide Dismutase; Superoxides; Time Factors; Vasoconstriction

2016
Mechanisms Underlying Interferon-γ-Induced Priming of Microglial Reactive Oxygen Species Production.
    PloS one, 2016, Volume: 11, Issue:9

    Topics: Acetylcysteine; Adenosine Triphosphate; Animals; Cell Line; Enzyme Inhibitors; Gene Expression Regulation; Glutathione; Glycoproteins; Imidazoles; Interferon-gamma; Membrane Glycoproteins; Mice; Microglia; NADPH Oxidase 2; NADPH Oxidases; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type II; p38 Mitogen-Activated Protein Kinases; Peroxynitrous Acid; Phenanthrolines; Potassium Channels, Inwardly Rectifying; Pyridines; Reactive Oxygen Species; Signal Transduction

2016
Inhibition of Oxidative Stress in Renal Ischemia-Reperfusion Injury.
    Anesthesia and analgesia, 2017, Volume: 124, Issue:1

    Topics: Allopurinol; Animals; Antioxidants; Apoptosis; Blood Urea Nitrogen; Creatinine; Cytoprotection; Disease Models, Animal; Enzyme Inhibitors; Kidney; Kidney Diseases; Lipid Peroxidation; Male; Metalloporphyrins; Monocytes; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Oxidative Stress; Peroxynitrous Acid; Rats, Sprague-Dawley; Reperfusion Injury; Superoxides; Xanthine Oxidase

2017
Recombinant heat shock protein 27 (HSP27/HSPB1) protects against cadmium-induced oxidative stress and toxicity in human cervical cancer cells.
    Cell stress & chaperones, 2017, Volume: 22, Issue:3

    Topics: Apoptosis; Cadmium; Cell Movement; Female; Fluorescent Dyes; HeLa Cells; HSP27 Heat-Shock Proteins; Humans; Microscopy, Fluorescence; NG-Nitroarginine Methyl Ester; Nitric Oxide; Oxidative Stress; Peroxynitrous Acid; Reactive Oxygen Species; Recombinant Proteins; Up-Regulation; Uterine Cervical Neoplasms

2017