Page last updated: 2024-09-03

peroxynitrous acid and n-methylaspartate

peroxynitrous acid has been researched along with n-methylaspartate in 9 studies

Compound Research Comparison

Studies
(peroxynitrous acid)
Trials
(peroxynitrous acid)
Recent Studies (post-2010)
(peroxynitrous acid)
Studies
(n-methylaspartate)
Trials
(n-methylaspartate)
Recent Studies (post-2010) (n-methylaspartate)
3,303211,23010,408591,902

Protein Interaction Comparison

ProteinTaxonomyperoxynitrous acid (IC50)n-methylaspartate (IC50)
Glutamate receptor ionotropic, NMDA 1 Rattus norvegicus (Norway rat)5.175
Glutamate receptor ionotropic, NMDA 2A Rattus norvegicus (Norway rat)5.175
Glutamate receptor ionotropic, NMDA 2BRattus norvegicus (Norway rat)5.175
Glutamate receptor ionotropic, NMDA 2CRattus norvegicus (Norway rat)5.175
Glutamate receptor ionotropic, NMDA 2DRattus norvegicus (Norway rat)5.175
Glutamate receptor ionotropic, NMDA 3BRattus norvegicus (Norway rat)5.175
Glutamate receptor ionotropic, NMDA 3ARattus norvegicus (Norway rat)5.175

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's8 (88.89)29.6817
2010's1 (11.11)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Abou-Mohamed, G; Caldwell, RB; Caldwell, RW; El-Remessy, AB; Green, K; Khalil, IE; Liou, GI; Matragoon, S; Roon, P; Tsai, NJ1
Cassano, T; Cuomo, V; Kendrick, KM; Steardo, L; Trabace, L; Tucci, P1
Fujimoto, S; Nagai, K; Nagasawa, K; Nishida, K; Shimohama, S1
Aarts, M; Arundine, M; Lau, A; Tymianski, M1
Anderson, JH; Pall, ML1
Arundine, M; Jones, M; Lau, A; Sun, HS; Tymianski, M1
Abe, T; Anrather, J; Girouard, H; Iadecola, C; Kawano, T; Kunz, A; Zhou, P1
Jin, S; Kawanokuchi, J; Mizuno, T; Sonobe, Y; Suzumura, A; Takeuchi, H; Wang, J1
Abdelsaid, MA; Al-Gayyar, MM; El-Remessy, AB; Matragoon, S; Pillai, BA1

Reviews

1 review(s) available for peroxynitrous acid and n-methylaspartate

ArticleYear
The vanilloid receptor as a putative target of diverse chemicals in multiple chemical sensitivity.
    Archives of environmental health, 2004, Volume: 59, Issue:7

    Topics: Environmental Exposure; Fungi; Humans; Multiple Chemical Sensitivity; N-Methylaspartate; Nitric Acid; Peroxynitrous Acid; Sick Building Syndrome; TRPV Cation Channels

2004

Other Studies

8 other study(ies) available for peroxynitrous acid and n-methylaspartate

ArticleYear
Neuroprotective effect of (-)Delta9-tetrahydrocannabinol and cannabidiol in N-methyl-D-aspartate-induced retinal neurotoxicity: involvement of peroxynitrite.
    The American journal of pathology, 2003, Volume: 163, Issue:5

    Topics: Animals; Apoptosis; Cannabidiol; Cyclic N-Oxides; Dose-Response Relationship, Drug; Dronabinol; In Situ Nick-End Labeling; Male; N-Methylaspartate; Neurons; Neuroprotective Agents; NG-Nitroarginine Methyl Ester; Oxidative Stress; Peroxynitrous Acid; Rats; Rats, Sprague-Dawley; Receptor, Cannabinoid, CB1; Retina; Reverse Transcriptase Polymerase Chain Reaction; Spin Labels; Time Factors

2003
The effects of nitric oxide on striatal serotoninergic transmission involve multiple targets: an in vivo microdialysis study in the awake rat.
    Brain research, 2004, May-22, Volume: 1008, Issue:2

    Topics: Animals; Cyclic GMP; Enzyme Inhibitors; Free Radical Scavengers; Guanylate Cyclase; Male; Microdialysis; N-Methylaspartate; Neostriatum; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Peroxynitrous Acid; Rats; Rats, Wistar; Serotonin; Signal Transduction; Superoxides; Synaptic Transmission

2004
Differential expression profiles of PLC-beta1 and -delta1 in primary cultured rat cortical neurons treated with N-methyl-D-aspartate and peroxynitrite.
    Neuroscience letters, 2004, Sep-02, Volume: 367, Issue:2

    Topics: Animals; Blotting, Western; Cell Survival; Cells, Cultured; Cerebral Cortex; Dizocilpine Maleate; Drug Interactions; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Isoenzymes; N-Methylaspartate; Neurons; Penicillamine; Peroxynitrous Acid; Rats; Tetrazolium Salts; Thiazoles; Time Factors; Type C Phospholipases

2004
Vulnerability of central neurons to secondary insults after in vitro mechanical stretch.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2004, Sep-15, Volume: 24, Issue:37

    Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Apoptosis; Brain Injuries; Calpain; Cell Nucleus; Cells, Cultured; Cysteine Endopeptidases; DNA; DNA Fragmentation; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; In Situ Nick-End Labeling; In Vitro Techniques; Intracellular Membranes; Membrane Potentials; Mice; Mitochondria; N-Methylaspartate; Neurons; Neurotoxins; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Oxidative Stress; Peroxynitrous Acid; Porphyrins; Reactive Oxygen Species; Receptors, N-Methyl-D-Aspartate; Recombinant Fusion Proteins; Stress, Mechanical; Superoxide Dismutase

2004
Inhibition of caspase-mediated apoptosis by peroxynitrite in traumatic brain injury.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2006, Nov-08, Volume: 26, Issue:45

    Topics: Animals; Apoptosis; Blotting, Western; Brain Injuries; Caspases; Cells, Cultured; Cerebral Cortex; Cytochromes c; Disease Models, Animal; Embryo, Mammalian; Enzyme Inhibitors; Immunohistochemistry; In Situ Nick-End Labeling; Male; Mice; Molsidomine; N-Methylaspartate; Neural Inhibition; Neurons; Nitric Oxide Donors; Peroxynitrous Acid; Physical Stimulation; Rats; Rats, Sprague-Dawley; Staurosporine

2006
iNOS-derived NO and nox2-derived superoxide confer tolerance to excitotoxic brain injury through peroxynitrite.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2007, Volume: 27, Issue:8

    Topics: Animals; Body Temperature; Brain; Brain Injuries; Carotid Arteries; Guanidines; Ischemic Preconditioning; Ligation; Lipopolysaccharides; Male; Membrane Glycoproteins; Metalloporphyrins; Mice; Mice, Inbred C57BL; Mice, Knockout; N-Methylaspartate; NADPH Oxidase 2; NADPH Oxidases; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase Type II; Peroxynitrous Acid; Superoxides; Tyrosine

2007
Interferon-beta is neuroprotective against the toxicity induced by activated microglia.
    Brain research, 2007, Nov-07, Volume: 1179

    Topics: Animals; Cells, Cultured; Coculture Techniques; Cytokines; Excitatory Amino Acid Agonists; Female; Glutamic Acid; Interferon Type I; Interleukin-1beta; Lipopolysaccharides; Mice; Mice, Inbred C57BL; Microglia; Molsidomine; N-Methylaspartate; Neurons; Neuroprotective Agents; Nitric Oxide; Peroxynitrous Acid; Pregnancy; Recombinant Proteins; Superoxides; Tumor Necrosis Factor-alpha

2007
Neurovascular protective effect of FeTPPs in N-methyl-D-aspartate model: similarities to diabetes.
    The American journal of pathology, 2010, Volume: 177, Issue:3

    Topics: Analysis of Variance; Animals; Apoptosis; Blotting, Western; Cell Count; Diabetic Retinopathy; Immunohistochemistry; In Situ Nick-End Labeling; Intravitreal Injections; Male; MAP Kinase Kinase Kinase 5; Metalloporphyrins; N-Methylaspartate; Neuroglia; Peroxynitrous Acid; Rats; Rats, Sprague-Dawley; Retinal Ganglion Cells; Retinal Vessels; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction

2010