Page last updated: 2024-09-03

peroxynitrous acid and guanine

peroxynitrous acid has been researched along with guanine in 21 studies

Compound Research Comparison

Studies
(peroxynitrous acid)
Trials
(peroxynitrous acid)
Recent Studies (post-2010)
(peroxynitrous acid)
Studies
(guanine)
Trials
(guanine)
Recent Studies (post-2010) (guanine)
3,303211,23016,2788224,809

Protein Interaction Comparison

ProteinTaxonomyperoxynitrous acid (IC50)guanine (IC50)
Purine nucleoside phosphorylaseHomo sapiens (human)5

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's15 (71.43)29.6817
2010's5 (23.81)24.3611
2020's1 (4.76)2.80

Authors

AuthorsStudies
Masuda, M; Nishino, H; Ohshima, H1
Masuda, M; Ohshima, H; Pignatelli, B; Souza, J; Szabó, C; Virág, L; Yermilov, V1
Gu, F; Jones, RA; Shallop, AJ; Stillwell, WG; Tannenbaum, SR; Wishnok, JS1
Halliwell, B; Ketsawatsakul, U; Whiteman, M1
Halliwell, B; Hong, HS; Jenner, A; Whiteman, M1
Fujioka, Y; Haginaka, J; Kunitomo, M; Morimoto, S; Yamaguchi, Y1
Niles, JC; Tannenbaum, SR; Wishnok, JS1
Tannenbaum, SR; Venkatarangan, L; Wishnok, JS; Yu, H1
Akaike, T; Barbin, A; Ohshima, H; Sawa, T; Tatemichi, M1
Ban, F; Boyd, RJ; Liu, N1
Hirose, M; Ishii, Y; Ito, R; Iwasaki, Y; Nakazawa, H; Nishikawa, A; Ogara, A; Okamura, T; Saito, K; Umemura, T1
Jena, NR; Mishra, PC1
Delaney, JC; Delaney, S; Essigmann, JM1
Mishra, PC; Shukla, PK1
Delaney, S; Jarem, DA; Wilson, NR1
Geacintov, NE; Shafirovich, V; Yun, BH1
Cui, L; Dedon, PC; Prestwich, EG; Taghizadeh, K; Tannenbaum, SR; Wishnok, JS; Ye, W1
Estlack, LE; Holwitt, EA; Noojin, GD; Rockwell, BA; Saunders, KE; Wigle, JC; Yakovlev, VV1
Alam, K; Ali, A; Dixit, K; Habib, S; Mir, AR; Tripathi, P1
Chang, YJ; Chao, MR; Chen, JL; Hsu, YW; Hu, CW; Wang, TS1
Gillespie, DG; Jackson, EK; Menshikova, EV; Mi, Z; Ritov, VB1

Reviews

1 review(s) available for peroxynitrous acid and guanine

ArticleYear
Peroxynitrite-induced oxidation and nitration products of guanine and 8-oxoguanine: structures and mechanisms of product formation.
    Nitric oxide : biology and chemistry, 2006, Volume: 14, Issue:2

    Topics: DNA; DNA Damage; Guanine; Nitrates; Nitric Oxide; Oxidation-Reduction; Oxyquinoline; Peroxynitrous Acid

2006

Other Studies

20 other study(ies) available for peroxynitrous acid and guanine

ArticleYear
Formation of 8-nitroguanosine in cellular RNA as a biomarker of exposure to reactive nitrogen species.
    Chemico-biological interactions, 2002, Feb-20, Volume: 139, Issue:2

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Biomarkers; Carcinoma; Cattle; Deoxyguanosine; Guanine; Humans; Lung Neoplasms; Molsidomine; Peroxynitrous Acid; RNA, Neoplasm; Tumor Cells, Cultured

2002
Detection of certain peroxynitrite-induced DNA modifications.
    Methods in molecular biology (Clifton, N.J.), 2002, Volume: 186

    Topics: Animals; Cattle; Chromatography, High Pressure Liquid; DNA; Guanine; Immunohistochemistry; Peroxynitrous Acid; Poly(ADP-ribose) Polymerases

2002
Peroxynitrite-induced reactions of synthetic oligo 2'-deoxynucleotides and DNA containing guanine: formation and stability of a 5-guanidino-4-nitroimidazole lesion.
    Biochemistry, 2002, Jun-11, Volume: 41, Issue:23

    Topics: Animals; Base Composition; Base Pair Mismatch; Cattle; Deoxyguanosine; DNA; DNA Damage; DNA, Single-Stranded; Guanine; Humans; Mutagens; Nitroimidazoles; Nucleic Acid Heteroduplexes; Oligodeoxyribonucleotides; Peroxynitrous Acid; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization

2002
A reassessment of the peroxynitrite scavenging activity of uric acid.
    Annals of the New York Academy of Sciences, 2002, Volume: 962

    Topics: alpha 1-Antitrypsin; Antioxidants; Ascorbic Acid; Benzothiazoles; Bicarbonates; Chromans; Coloring Agents; Glutathione; Guanine; Humans; Indicators and Reagents; Peroxynitrous Acid; Pyrogallol; Reactive Nitrogen Species; Serine Proteinase Inhibitors; Sulfonic Acids; Tyrosine; Uric Acid

2002
Loss of oxidized and chlorinated bases in DNA treated with reactive oxygen species: implications for assessment of oxidative damage in vivo.
    Biochemical and biophysical research communications, 2002, Aug-30, Volume: 296, Issue:4

    Topics: Animals; Cattle; Chlorine; Cytosine; DNA; DNA Damage; Dose-Response Relationship, Drug; Gas Chromatography-Mass Spectrometry; Guanine; Humans; Hydrogen Peroxide; Hypochlorous Acid; Nitrogen; Oxidative Stress; Oxygen; Peroxynitrous Acid; Reactive Oxygen Species; Thymus Gland; Uracil

2002
Facilitated nitration and oxidation of LDL in cigarette smokers.
    European journal of clinical investigation, 2005, Volume: 35, Issue:3

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Adult; Biomarkers; Chromatography, High Pressure Liquid; Female; Guanine; Humans; Lipoproteins, LDL; Male; Oxidation-Reduction; Oxidative Stress; Peroxynitrous Acid; Smoking; Thiobarbituric Acid Reactive Substances; Tyrosine; Vitamin E

2005
Quantitation of four guanine oxidation products from reaction of DNA with varying doses of peroxynitrite.
    Chemical research in toxicology, 2005, Volume: 18, Issue:12

    Topics: Animals; Cattle; Cells, Cultured; Chromatography, High Pressure Liquid; DNA; Guanidines; Guanine; Guanosine; Hydantoins; Molecular Structure; Oxazolone; Oxidation-Reduction; Peroxynitrous Acid; Spectrometry, Mass, Electrospray Ionization; Spiro Compounds

2005
Analysis of urinary 8-nitroguanine, a marker of nitrative nucleic acid damage, by high-performance liquid chromatography-electrochemical detection coupled with immunoaffinity purification: association with cigarette smoking.
    Free radical biology & medicine, 2006, Feb-15, Volume: 40, Issue:4

    Topics: Adult; Antibodies, Monoclonal; Ascites; Biological Assay; Biomarkers; Chromatography, Affinity; Chromatography, High Pressure Liquid; DNA Damage; Electrochemistry; Female; Guanine; Humans; Male; Nitrogen Dioxide; Nucleic Acids; Peroxynitrous Acid; Reactive Nitrogen Species; Smoking; Spectrometry, Mass, Electrospray Ionization; Xanthines

2006
Modeling competitive reaction mechanisms of peroxynitrite oxidation of guanine.
    The journal of physical chemistry. A, 2006, Aug-17, Volume: 110, Issue:32

    Topics: Cations; Free Radicals; Guanine; Models, Chemical; Molecular Structure; Nitroimidazoles; Oxidation-Reduction; Peroxynitrous Acid; Water

2006
Development of quantitative analysis of 8-nitroguanine concomitant with 8-hydroxydeoxyguanosine formation by liquid chromatography with mass spectrometry and glyoxal derivatization.
    Journal of pharmaceutical and biomedical analysis, 2007, Apr-11, Volume: 43, Issue:5

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Buffers; Cattle; Chelating Agents; Chromatography, Liquid; Deoxyguanosine; DNA; DNA Damage; Dose-Response Relationship, Drug; Glyoxal; Guanine; Hydrogen-Ion Concentration; Mass Spectrometry; Molecular Structure; Oxidants; Pentetic Acid; Peroxynitrous Acid; Reproducibility of Results; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization; Spectrophotometry, Ultraviolet; Temperature; Thymus Gland; Time Factors

2007
Formation of 8-nitroguanine and 8-oxoguanine due to reactions of peroxynitrite with guanine.
    Journal of computational chemistry, 2007, Volume: 28, Issue:8

    Topics: Guanine; Isomerism; Models, Molecular; Molecular Conformation; Nitrogen; Oxidation-Reduction; Peroxynitrous Acid; Thermodynamics

2007
Chemical-biological fingerprinting: probing the properties of DNA lesions formed by peroxynitrite.
    Chemical research in toxicology, 2007, Volume: 20, Issue:11

    Topics: Chromatography, High Pressure Liquid; DNA Damage; Escherichia coli; Guanine; Molsidomine; Mutation; Peroxynitrous Acid; SOS Response, Genetics; Spectrometry, Mass, Electrospray Ionization

2007
Catalytic involvement of CO2 in the mutagenesis caused by reactions of ONOO(-) with guanine.
    The journal of physical chemistry. B, 2008, Apr-17, Volume: 112, Issue:15

    Topics: Carbon Dioxide; Catalysis; Computer Simulation; Guanine; Models, Chemical; Mutagenesis; Oxidation-Reduction; Peroxynitrous Acid; Solvents

2008
Structure-dependent DNA damage and repair in a trinucleotide repeat sequence.
    Biochemistry, 2009, Jul-21, Volume: 48, Issue:28

    Topics: Base Sequence; DNA Damage; DNA Glycosylases; DNA Repair; Guanine; Humans; Kinetics; Molecular Sequence Data; Nucleic Acid Conformation; Peroxynitrous Acid; Substrate Specificity; Time Factors; Trinucleotide Repeat Expansion

2009
Generation of guanine-thymidine cross-links in DNA by peroxynitrite/carbon dioxide.
    Chemical research in toxicology, 2011, Jul-18, Volume: 24, Issue:7

    Topics: Alkaline Phosphatase; Animals; Bicarbonates; Carbon Dioxide; Cattle; Chromatography, High Pressure Liquid; DNA; Guanidines; Guanine; Hydrogen-Ion Concentration; Nitroimidazoles; Oligonucleotides; Oxidation-Reduction; Peroxynitrous Acid; Tandem Mass Spectrometry; Thymidine; Water

2011
Comparative analysis of four oxidized guanine lesions from reactions of DNA with peroxynitrite, singlet oxygen, and γ-radiation.
    Chemical research in toxicology, 2013, Feb-18, Volume: 26, Issue:2

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Cattle; Deoxyguanosine; DNA; Gamma Rays; Guanidines; Guanine; Guanosine; Hydantoins; Oxidants; Oxidation-Reduction; Peroxynitrous Acid; Rose Bengal; Singlet Oxygen; Spiro Compounds

2013
No effect of femtosecond laser pulses on M13, E. coli, DNA, or protein.
    Journal of biomedical optics, 2014, Volume: 19, Issue:1

    Topics: Animals; Bacteriophage M13; Buffers; CHO Cells; Cricetinae; Cricetulus; DNA; DNA, Viral; Electrophoresis; Electrophoresis, Agar Gel; Escherichia coli; Guanine; Hydrogen Peroxide; Iron; Lasers; Macromolecular Substances; Peptides; Peroxynitrous Acid; Plasmids; Potoroidae; Proteins; Reactive Oxygen Species; Serum Albumin, Bovine; Spectrum Analysis, Raman; T-Lymphocytes; Time Factors; Water

2014
Peroxynitrite modified DNA presents better epitopes for anti-DNA autoantibodies in diabetes type 1 patients.
    Cellular immunology, 2014, Volume: 290, Issue:1

    Topics: Antibodies, Antinuclear; Diabetes Mellitus, Type 1; DNA; DNA Adducts; DNA Breaks; Epitopes; Guanine; Humans; Immunoglobulin G; Nitrites; Peroxynitrous Acid; Plasmids

2014
Comprehensive analysis of the formation and stability of peroxynitrite-derived 8-nitroguanine by LC-MS/MS: Strategy for the quantitative analysis of cellular 8-nitroguanine.
    Free radical biology & medicine, 2016, Volume: 101

    Topics: Animals; Cattle; Cell Line; CHO Cells; Chromatography, High Pressure Liquid; Cricetulus; DNA; Endothelial Cells; Guanine; Half-Life; Humans; Hydrogen-Ion Concentration; Kinetics; Limit of Detection; Observer Variation; Peroxynitrous Acid; Reproducibility of Results; Tandem Mass Spectrometry

2016
Biochemical pathways of 8-aminoguanine production in Sprague-Dawley and Dahl salt-sensitive rats.
    Biochemical pharmacology, 2022, Volume: 201

    Topics: Animals; Antihypertensive Agents; Guanine; Hypertension; Kidney; Peroxynitrous Acid; Rats; Rats, Inbred Dahl; Rats, Sprague-Dawley

2022