Page last updated: 2024-09-03

peroxynitrous acid and glutamic acid

peroxynitrous acid has been researched along with glutamic acid in 12 studies

Compound Research Comparison

Studies
(peroxynitrous acid)
Trials
(peroxynitrous acid)
Recent Studies (post-2010)
(peroxynitrous acid)
Studies
(glutamic acid)
Trials
(glutamic acid)
Recent Studies (post-2010) (glutamic acid)
3,303211,23041,75745212,876

Protein Interaction Comparison

ProteinTaxonomyperoxynitrous acid (IC50)glutamic acid (IC50)
Chain A, GLUTAMATE RECEPTOR SUBUNIT 2Rattus norvegicus (Norway rat)0.821
Chain A, Glutamate Receptor Subunit 2Rattus norvegicus (Norway rat)0.821
Chain B, Glutamate Receptor Subunit 2Rattus norvegicus (Norway rat)0.821
Metabotropic glutamate receptor 8Homo sapiens (human)0.0057
Glutamate receptor ionotropic, NMDA 2DHomo sapiens (human)0.07
Glutamate receptor ionotropic, NMDA 3BHomo sapiens (human)0.07
Glutamate receptor 1Rattus norvegicus (Norway rat)0.5885
Glutamate receptor 2Rattus norvegicus (Norway rat)0.5885
Glutamate receptor 3Rattus norvegicus (Norway rat)0.5885
Glutamate receptor 4Rattus norvegicus (Norway rat)0.5885
Glutamate receptor ionotropic, kainate 1Rattus norvegicus (Norway rat)0.38
Glutamate receptor ionotropic, NMDA 1 Rattus norvegicus (Norway rat)0.1533
Glutamate receptor ionotropic, kainate 2Rattus norvegicus (Norway rat)0.38
Glutamate receptor 1Homo sapiens (human)0.613
Glutamate receptor 2Homo sapiens (human)0.613
Glutamate receptor 3Homo sapiens (human)0.613
Glutamate receptor ionotropic, kainate 3Rattus norvegicus (Norway rat)0.38
Excitatory amino acid transporter 1Homo sapiens (human)207
Glutamate receptor 4Homo sapiens (human)0.613
Glutamate receptor ionotropic, NMDA 2A Rattus norvegicus (Norway rat)0.1533
Glutamate receptor ionotropic, NMDA 2BRattus norvegicus (Norway rat)0.1533
Glutamate receptor ionotropic, NMDA 2CRattus norvegicus (Norway rat)0.1533
Glutamate receptor ionotropic, kainate 4Rattus norvegicus (Norway rat)0.38
Glutamate receptor ionotropic, NMDA 1Homo sapiens (human)0.07
Glutamate receptor ionotropic, NMDA 2AHomo sapiens (human)0.07
Glutamate receptor ionotropic, NMDA 2BHomo sapiens (human)0.07
Glutamate receptor ionotropic, NMDA 2CHomo sapiens (human)0.07
Glutamate receptor ionotropic, NMDA 2DRattus norvegicus (Norway rat)0.1533
Glutamate receptor ionotropic, kainate 5Rattus norvegicus (Norway rat)0.38
Glutamate receptor ionotropic, NMDA 3AHomo sapiens (human)0.07
Glutamate receptor ionotropic, NMDA 3BRattus norvegicus (Norway rat)0.1533
Glutamate receptor ionotropic, NMDA 3ARattus norvegicus (Norway rat)0.1533

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's8 (66.67)29.6817
2010's4 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Delivoria-Papadopoulos, M; Mishra, OP1
Di Stasi, AM; Macchia, G; Mallozzi, C; Maura, G; Minetti, M; Petrucci, TC1
Chan, SH; Hsu, KS; Huang, CC1
Appel, SH; Beers, DR; He, Y; Henkel, JS; Le, W; Simpson, EP; Xiao, Q; Xie, W; Yen, AA; Zhao, W1
Clark, RS; Du, L; Dunsmore, KE; Jenkins, LW; Lai, Y; Wong, HR1
Brown, JM; Quinton, MS; Yamamoto, BK1
Bolton, C; Bowman, SR; Flower, RJ; Scott, GS; Smith, T1
Jin, S; Kawanokuchi, J; Mizuno, T; Sonobe, Y; Suzumura, A; Takeuchi, H; Wang, J1
Babu, GN; Kumar, A; Singh, RL1
Bryant, L; Chen, Z; Cuzzocrea, S; Doyle, T; Masini, E; Mastroianni, R; Mollace, V; Muscoli, C; Salvemini, D1
Barbosa, RM; Dias, C; Ferreiro, E; Laranjinha, J; Ledo, A; Lourenço, CF1
BassiriRad, NM; Bui, L; Doyle, T; Forte, BL; Largent-Milnes, TM; Mantyh, PW; Neumann, WL; Salvemini, D; Slosky, LM; Staatz, WD; Symons, AM; Thompson, M; Vanderah, TW1

Other Studies

12 other study(ies) available for peroxynitrous acid and glutamic acid

ArticleYear
Nitric oxide-mediated Ca++-influx in neuronal nuclei and cortical synaptosomes of normoxic and hypoxic newborn piglets.
    Neuroscience letters, 2002, Jan-25, Volume: 318, Issue:2

    Topics: Adenosine Triphosphate; Animals; Asphyxia Neonatorum; Calcium; Calcium Signaling; Cell Nucleus; Cerebral Cortex; Free Radicals; Glutamic Acid; Glycine; Humans; Hypoxia, Brain; Infant, Newborn; Nerve Degeneration; Neurons; Nitric Oxide; Nitric Oxide Donors; Oxidative Stress; Peroxynitrous Acid; Phosphocreatine; Receptors, N-Methyl-D-Aspartate; Swine; Synaptosomes

2002
Peroxynitrite affects exocytosis and SNARE complex formation and induces tyrosine nitration of synaptic proteins.
    Journal of neurochemistry, 2002, Volume: 82, Issue:2

    Topics: Animals; Brain Chemistry; Dose-Response Relationship, Drug; Exocytosis; Fluorescent Dyes; Glutamic Acid; Macromolecular Substances; Male; Membrane Proteins; Munc18 Proteins; Nerve Tissue Proteins; Peroxynitrous Acid; Proteins; Rats; Rats, Sprague-Dawley; SNARE Proteins; Sodium Bicarbonate; Sodium Dodecyl Sulfate; Synaptosomal-Associated Protein 25; Synaptosomes; Tyrosine; Vesicular Transport Proteins

2002
3-Morpholinylsydnonimine inhibits glutamatergic transmission in rat rostral ventrolateral medulla via peroxynitrite formation and adenosine release.
    Molecular pharmacology, 2004, Volume: 66, Issue:3

    Topics: Adenosine; Animals; Calcium Channels, N-Type; Glutamic Acid; In Vitro Techniques; Male; Medulla Oblongata; Molsidomine; Nitric Oxide Donors; Peroxynitrous Acid; Rats; Rats, Sprague-Dawley; Synaptic Transmission

2004
Activated microglia initiate motor neuron injury by a nitric oxide and glutamate-mediated mechanism.
    Journal of neuropathology and experimental neurology, 2004, Volume: 63, Issue:9

    Topics: Amino Acid Transport System X-AG; Amyotrophic Lateral Sclerosis; Animals; Astrocytes; Catalase; Cell Communication; Cell Death; Cells, Cultured; Coculture Techniques; Free Radicals; Glutamic Acid; Glutathione; Microglia; Motor Neurons; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Oxidative Stress; Peroxynitrous Acid; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Spinal Cord

2004
Selectively increasing inducible heat shock protein 70 via TAT-protein transduction protects neurons from nitrosative stress and excitotoxicity.
    Journal of neurochemistry, 2005, Volume: 94, Issue:2

    Topics: Animals; Animals, Newborn; Blotting, Western; Cell Death; Cells, Cultured; Cerebral Cortex; Cloning, Molecular; Dose-Response Relationship, Drug; Flow Cytometry; Gene Products, tat; Glutamic Acid; HSP70 Heat-Shock Proteins; Humans; Immunohistochemistry; Lactate Dehydrogenases; Neurons; Peroxynitrous Acid; Rats; Rats, Sprague-Dawley; Subcellular Fractions; Tetrazolium Salts; Thiazoles; Transduction, Genetic

2005
Methamphetamine-induced inhibition of mitochondrial complex II: roles of glutamate and peroxynitrite.
    Journal of neurochemistry, 2005, Volume: 95, Issue:2

    Topics: Animals; Central Nervous System Stimulants; Dose-Response Relationship, Drug; Electron Transport; Electron Transport Complex II; Enzyme Activation; Excitatory Amino Acid Antagonists; Glutamic Acid; Male; Methamphetamine; Mitochondria; Nitric Oxide Synthase; Peroxynitrous Acid; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Succinate Dehydrogenase

2005
Glutamate-stimulated peroxynitrite production in a brain-derived endothelial cell line is dependent on N-methyl-D-aspartate (NMDA) receptor activation.
    Biochemical pharmacology, 2007, Jan-15, Volume: 73, Issue:2

    Topics: Animals; Blotting, Western; Brain; Cells, Cultured; Endothelium, Vascular; Glutamic Acid; Mice; Nitric Oxide; Nitric Oxide Synthase; Peroxynitrous Acid; Receptors, N-Methyl-D-Aspartate

2007
Interferon-beta is neuroprotective against the toxicity induced by activated microglia.
    Brain research, 2007, Nov-07, Volume: 1179

    Topics: Animals; Cells, Cultured; Coculture Techniques; Cytokines; Excitatory Amino Acid Agonists; Female; Glutamic Acid; Interferon Type I; Interleukin-1beta; Lipopolysaccharides; Mice; Mice, Inbred C57BL; Microglia; Molsidomine; N-Methylaspartate; Neurons; Neuroprotective Agents; Nitric Oxide; Peroxynitrous Acid; Pregnancy; Recombinant Proteins; Superoxides; Tumor Necrosis Factor-alpha

2007
Cell death mechanisms in the early stages of acute glutamate neurotoxicity.
    Neuroscience research, 2010, Volume: 66, Issue:3

    Topics: Animals; bcl-2-Associated X Protein; Calcium; Caspase 3; Caspase 9; Cell Death; Cell Size; Cerebral Cortex; Glutamic Acid; Glutathione; Male; Membrane Potential, Mitochondrial; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Peroxynitrous Acid; Proto-Oncogene Proteins c-bcl-2; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; RNA, Messenger

2010
NMDA-receptor activation and nitroxidative regulation of the glutamatergic pathway during nociceptive processing.
    Pain, 2010, Volume: 149, Issue:1

    Topics: Animals; Glutamic Acid; Hyperalgesia; Male; Oxidation-Reduction; Peroxynitrous Acid; Rats; Rats, Sprague-Dawley; Signal Transduction; Spinal Cord

2010
Age-dependent changes in the glutamate-nitric oxide pathway in the hippocampus of the triple transgenic model of Alzheimer's disease: implications for neurometabolic regulation.
    Neurobiology of aging, 2016, Volume: 46

    Topics: Aging; Alzheimer Disease; Animals; Disease Models, Animal; Energy Metabolism; Glutamic Acid; Hippocampus; Mice, Transgenic; Microelectrodes; Mitochondria; Neurotransmitter Agents; Nitric Oxide; Oxidative Phosphorylation; Oxygen Consumption; Peroxynitrous Acid; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission; Tyrosine

2016
The cystine/glutamate antiporter system xc- drives breast tumor cell glutamate release and cancer-induced bone pain.
    Pain, 2016, Volume: 157, Issue:11

    Topics: Adenocarcinoma; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antiporters; Bone Neoplasms; Breast Neoplasms; Calcium-Binding Proteins; Cancer Pain; Cell Line, Tumor; Disease Models, Animal; Female; Gene Expression Regulation, Neoplastic; Glutamic Acid; Heterografts; Metalloporphyrins; Mice; Mice, Inbred BALB C; Peroxynitrous Acid; Sulfasalazine; Time Factors

2016