peroxynitrous acid has been researched along with ebselen in 23 studies
| Studies (peroxynitrous acid) | Trials (peroxynitrous acid) | Recent Studies (post-2010) (peroxynitrous acid) | Studies (ebselen) | Trials (ebselen) | Recent Studies (post-2010) (ebselen) |
|---|---|---|---|---|---|
| 3,303 | 21 | 1,230 | 839 | 9 | 366 |
| Protein | Taxonomy | peroxynitrous acid (IC50) | ebselen (IC50) |
|---|---|---|---|
| RNA polymerase beta subunit (EC 2.7.7.6), partial | Escherichia coli | 11.6872 | |
| Arrestin, beta 1 | Homo sapiens (human) | 1.524 | |
| MPI protein | Homo sapiens (human) | 0.19 | |
| glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase | Plasmodium berghei | 15.0867 | |
| TPA: protein transporter TIM10 | Saccharomyces cerevisiae S288C | 5.29 | |
| TPA: protein transporter TIM23 | Saccharomyces cerevisiae S288C | 0.88 | |
| hexokinase | Trypanosoma brucei brucei TREU927 | 0.9009 | |
| Spike glycoprotein | Betacoronavirus England 1 | 0.67 | |
| Replicase polyprotein 1ab | Betacoronavirus England 1 | 0.67 | |
| neutrophil cytosol factor 1 | Homo sapiens (human) | 0.39 | |
| phosphomannomutase 2 | Homo sapiens (human) | 0.672 | |
| perilipin-5 | Homo sapiens (human) | 1.101 | |
| glucose-6-phosphate 1-dehydrogenase isoform b | Homo sapiens (human) | 13.2 | |
| phosphoethanolamine/phosphocholine phosphatase isoform 1 | Homo sapiens (human) | 0.111 | |
| perilipin-1 | Homo sapiens (human) | 3.41 | |
| eukaryotic translation initiation factor 4 gamma 1 isoform 4 | Homo sapiens (human) | 1.15 | |
| eukaryotic translation initiation factor 4E isoform 1 | Mus musculus (house mouse) | 1.15 | |
| 1-acylglycerol-3-phosphate O-acyltransferase ABHD5 isoform a | Homo sapiens (human) | 2.2555 | |
| Sulfhydryl oxidase 1 | Homo sapiens (human) | 5.4 | |
| Transmembrane protease serine 2 | Homo sapiens (human) | 0.67 | |
| Prostaglandin G/H synthase 1 | Bos taurus (cattle) | 2.1 | |
| Gamma-butyrobetaine dioxygenase | Homo sapiens (human) | 0.742 | |
| Bile salt export pump | Homo sapiens (human) | 10 | |
| Procathepsin L | Homo sapiens (human) | 0.67 | |
| Replicase polyprotein 1a | Severe acute respiratory syndrome-related coronavirus | 0.67 | |
| Replicase polyprotein 1ab | Human coronavirus 229E | 0.67 | |
| Replicase polyprotein 1ab | Severe acute respiratory syndrome-related coronavirus | 0.62 | |
| Replicase polyprotein 1ab | Severe acute respiratory syndrome coronavirus 2 | 0.7928 | |
| Macrophage migration inhibitory factor | Homo sapiens (human) | 2.4 | |
| Insulin-degrading enzyme | Homo sapiens (human) | 0.028 | |
| Urease subunit alpha | Helicobacter pylori 26695 | 3.745 | |
| Toxin B | Clostridioides difficile | 0.0172 | |
| Caspase-1 | Homo sapiens (human) | 4.04 | |
| Bifunctional epoxide hydrolase 2 | Homo sapiens (human) | 0.7575 | |
| Methionine aminopeptidase 2 | Homo sapiens (human) | 2.43 | |
| Spike glycoprotein | Severe acute respiratory syndrome-related coronavirus | 0.67 | |
| Urease subunit beta | Helicobacter pylori 26695 | 3.745 | |
| UDP-glucose 4-epimerase | Homo sapiens (human) | 0.014 | |
| Structural capsid protein | Human immunodeficiency virus 1 | 0.0467 | |
| Histone-lysine N-methyltransferase EHMT2 | Homo sapiens (human) | 0.4 | |
| Angiotensin-converting enzyme 2 | Homo sapiens (human) | 0.67 | |
| Histone-lysine N-methyltransferase EHMT1 | Homo sapiens (human) | 0.73 | |
| Histone deacetylase 6 | Homo sapiens (human) | 4.05 | |
| Histone deacetylase 9 | Homo sapiens (human) | 3.7 | |
| Histone deacetylase 5 | Homo sapiens (human) | 3.4 | |
| large T antigen | Betapolyomavirus macacae | 13.91 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 16 (69.57) | 29.6817 |
| 2010's | 6 (26.09) | 24.3611 |
| 2020's | 1 (4.35) | 2.80 |
| Authors | Studies |
|---|---|
| Brodsky, S; Fujita, T; Goligorsky, MS; Nakao, A; Noiri, E; Ohno, M; Tsukahara, H; Uchida, K | 1 |
| Brodsky, SV; Chen, J; Goligorsky, DM; Goligorsky, MS; Gross, SS; Hampel, DJ; Li, H | 1 |
| Geletii, YV; Hill, CL; Hirao, K; Musaev, DG | 1 |
| Allen, DA; Harwood, S; Raftery, MJ; Varagunam, M; Yaqoob, MM | 1 |
| Bubolz, A; Gutterman, DD; Li, H; Liu, Y; Rusch, NJ | 1 |
| Brodsky, SV; Chander, PN; Crabtree, M; Elitok, S; Gealekman, O; Goligorsky, MS; Gross, SS; Tojo, A | 1 |
| Dekhuijzen, PN; Ennen, L; Heunks, LM; van der Heijden, HF; van Kuppevelt, TH; Versteeg, EM; Vina, J; Zhu, X | 1 |
| Mira, L; Santos, MR | 1 |
| Haneda, M; Li, W; Murakami, K; Qiao, S; Tsubouchi, R; Yoshino, M | 1 |
| Bilgic, H; Coskun, O; Korkmaz, A; Oter, S; Ozler, M; Sadir, S; Topal, T | 1 |
| Bubolz, AH; Gutterman, DD; Liu, Y; Newman, DK; Newman, PJ; Shi, Y | 1 |
| Faraci, F; Heistad, D; Ohashi, M | 1 |
| Kołodziejczyk, J; Nowak, P; Olas, B; Saluk-Juszczak, J; Wachowicz, B | 1 |
| Karayilanoglu, T; Korkmaz, A; Kurt, B; Mollaoglu, H; Oter, S; Topal, T; Yaren, H | 1 |
| Bubolz, AH; Gutterman, DD; Larsen, BT; Liu, Y; Wu, Q | 1 |
| Fujii, M; Kohno, S; Mizutani, N; Nabe, T; Yoshino, S | 1 |
| Agbani, EO; Coats, P; Wadsworth, RM | 1 |
| Bhabak, KP; Jakka, SR; Mugesh, G; Roy, G; Vernekar, AA | 1 |
| Almeida, LM; Brito, PM; Calcerrada, P; de Bem, AF; Dinis, TC; Fiuza, B; Peluffo, G; Radi, R; Rocha, JB; Trujillo, M | 1 |
| Huang, L; Li, X; Liu, A; Lu, C; Luo, HB; Luo, Z; Sheng, J; Sun, Y; Yan, J | 1 |
| Chen, J; Huang, L; Li, X; Luo, Z; Mao, F; Zhou, Q | 1 |
| Arias, P; Del Rio, R; Iturriaga, R; Moya, EA; Oyarce, MP; Varela, C | 1 |
| Condeles, AL; Toledo Junior, JC | 1 |
23 other study(ies) available for peroxynitrous acid and ebselen
| Article | Year |
|---|---|
Oxidative and nitrosative stress in acute renal ischemia.
Topics: Animals; Azoles; Blotting, Western; Cell Line; Cyclic N-Oxides; DNA Damage; Enzyme Inhibitors; Free Radical Scavengers; Immunohistochemistry; Ischemia; Isoindoles; Kidney; Lipid Peroxidation; Lysine; Macrophages; Male; Mice; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; Organoselenium Compounds; Oxidative Stress; Peroxynitrous Acid; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Spin Labels; Superoxide Dismutase; Tyrosine | 2001 |
Glycated collagen I induces premature senescence-like phenotypic changes in endothelial cells.
Topics: Animals; Apoptosis; Arginine; Azoles; beta-Galactosidase; Cells, Cultured; Cellular Senescence; Collagen Type I; Diabetes Mellitus, Experimental; Endothelium, Vascular; Free Radical Scavengers; Glycosylation; Humans; Isoindoles; Kinetics; Metalloporphyrins; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Organoselenium Compounds; Peroxynitrous Acid; Phenotype; Rats; Rats, Zucker | 2002 |
Can the ebselen derivatives catalyze the isomerization of peroxynitrite to nitrate?
Topics: Anions; Azoles; Catalysis; Glutathione Peroxidase; Isoindoles; Isomerism; Models, Molecular; Molecular Conformation; Nitrates; Organoselenium Compounds; Peroxynitrous Acid; Solvents; Thermodynamics | 2003 |
High glucose-induced oxidative stress causes apoptosis in proximal tubular epithelial cells and is mediated by multiple caspases.
Topics: Animals; Antioxidants; Apoptosis; Aspartic Acid; Azoles; Caspase Inhibitors; Caspases; Cell Line; Cysteine Proteinase Inhibitors; Dose-Response Relationship, Drug; Epithelial Cells; Glucose; Isoindoles; Kidney Tubules, Proximal; Nitrites; Oligopeptides; Organoselenium Compounds; Oxidative Stress; Peroxynitrous Acid | 2003 |
Nitration and functional loss of voltage-gated K+ channels in rat coronary microvessels exposed to high glucose.
Topics: Animals; Azoles; Coronary Vessels; Free Radical Scavengers; Glucose; Isoindoles; Male; Membrane Potentials; Microcirculation; Nitrogen; Organoselenium Compounds; Patch-Clamp Techniques; Peroxynitrous Acid; Potassium Channels, Voltage-Gated; Rats; Rats, Sprague-Dawley; Uric Acid; Vasodilation | 2004 |
Nephropathy in Zucker diabetic fat rat is associated with oxidative and nitrosative stress: prevention by chronic therapy with a peroxynitrite scavenger ebselen.
Topics: Animals; Antioxidants; Azoles; Diabetic Nephropathies; Isoindoles; Nitrosation; Obesity; Organoselenium Compounds; Oxidative Stress; Peroxynitrous Acid; Rats; Rats, Zucker | 2004 |
Hypoxia-induced dysfunction of rat diaphragm: role of peroxynitrite.
Topics: Animals; Azoles; Diaphragm; Enzyme Inhibitors; Hypoxia; In Vitro Techniques; Isoindoles; Lipid Peroxidation; Male; Muscle Contraction; Muscle Fatigue; omega-N-Methylarginine; Organoselenium Compounds; Peroxynitrous Acid; Rats; Rats, Wistar; Tyrosine | 2005 |
Protection by flavonoids against the peroxynitrite-mediated oxidation of dihydrorhodamine.
Topics: Antioxidants; Azoles; Flavonoids; Isoindoles; Organoselenium Compounds; Oxidation-Reduction; Peroxynitrous Acid; Rhodamines; Structure-Activity Relationship | 2004 |
Involvement of peroxynitrite in capsaicin-induced apoptosis of C6 glioma cells.
Topics: Animals; Annexin A5; Apoptosis; Azoles; Blotting, Western; Capsaicin; Cell Count; Cell Line, Tumor; Comet Assay; Dose-Response Relationship, Drug; Drug Interactions; Gene Expression Regulation, Neoplastic; Glioma; In Situ Nick-End Labeling; Isoindoles; Mice; Neuroprotective Agents; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; Organoselenium Compounds; Peroxynitrous Acid; Phenanthridines; Superoxide Dismutase; Time Factors | 2005 |
Peroxynitrite may be involved in bladder damage caused by cyclophosphamide in rats.
Topics: Animals; Antioxidants; Azoles; Cyclophosphamide; Cystitis; Free Radical Scavengers; Guanidines; Isoindoles; Male; Organoselenium Compounds; Peroxynitrous Acid; Rats; Rats, Wistar | 2005 |
Peroxynitrite reduces the endothelium-derived hyperpolarizing factor component of coronary flow-mediated dilation in PECAM-1-knockout mice.
Topics: Animals; Azoles; Biological Factors; Coronary Vessels; Gene Deletion; Hydrogen Peroxide; Indomethacin; Isoindoles; Male; Mice; Mice, Knockout; NG-Nitroarginine Methyl Ester; Nitric Oxide; Organoselenium Compounds; Peroxynitrous Acid; Platelet Endothelial Cell Adhesion Molecule-1; Prostaglandins; Tyrosine; Vasodilation | 2006 |
Peroxynitrite hyperpolarizes smooth muscle and relaxes internal carotid artery in rabbit via ATP-sensitive K+ channels.
Topics: Animals; Antioxidants; Azoles; Carotid Artery, Internal; Catalase; Charybdotoxin; Glyburide; Hydrogen Peroxide; Hypoglycemic Agents; In Vitro Techniques; Isoindoles; Male; Membrane Potentials; Muscle Relaxation; Muscle Tonus; Muscle, Smooth, Vascular; Organoselenium Compounds; Peroxynitrous Acid; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Calcium-Activated; Rabbits; Reactive Oxygen Species; Superoxide Dismutase; Tetraethylammonium Compounds; Uric Acid | 2005 |
The protective effects of selenoorganic compounds against peroxynitrite-induced changes in plasma proteins and lipids.
Topics: Animals; Antioxidants; Azoles; Benzamides; Blood Proteins; Goats; Humans; Isoindoles; Lipid Peroxidation; Lipids; Organoselenium Compounds; Oxidation-Reduction; Peroxynitrous Acid; Rabbits; Selenium Compounds; Sheep | 2006 |
Lung toxicity of nitrogen mustard may be mediated by nitric oxide and peroxynitrite in rats.
Topics: Alkylating Agents; Animals; Antioxidants; Azoles; Guanidines; Isoindoles; Lung Diseases; Male; Mechlorethamine; Nitrates; Nitric Oxide; Nitric Oxide Synthase Type II; Nitrites; Organoselenium Compounds; Peroxynitrous Acid; Rats; Rats, Wistar | 2007 |
Ebselen reduces nitration and restores voltage-gated potassium channel function in small coronary arteries of diabetic rats.
Topics: Adenylyl Cyclases; Animals; Antioxidants; Azoles; Colforsin; Coronary Vessels; Cyclic AMP; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Enzyme Activators; Isoindoles; Kv1.2 Potassium Channel; Kv1.5 Potassium Channel; Male; Membrane Potentials; Muscle, Smooth, Vascular; Organoselenium Compounds; Oxidative Stress; Peroxynitrous Acid; Potassium Channel Blockers; Protein Subunits; Rats; Rats, Sprague-Dawley; Research Design; Triterpenes; Tyrosine; Vasodilation | 2007 |
Involvement of peroxynitrite in pollen-induced nasal blockage in guinea pigs.
Topics: Administration, Intranasal; Allergens; Allopurinol; Analysis of Variance; Animals; Antioxidants; Azoles; Cryptomeria; Disease Models, Animal; Guinea Pigs; Isoindoles; Leukotriene D4; Male; Nasal Obstruction; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Organoselenium Compounds; Peroxynitrous Acid; Pollen; Rhinitis, Allergic, Seasonal; Xanthine Oxidase | 2008 |
Acute hypoxia stimulates intracellular peroxynitrite formation associated with pulmonary artery smooth muscle cell proliferation.
Topics: Acute Disease; Animals; Azoles; Cattle; Cell Culture Techniques; Cell Hypoxia; Cell Proliferation; Cells, Cultured; Endothelial Cells; Free Radical Scavengers; Hypoxia; Isoindoles; Muscle, Smooth, Vascular; Organoselenium Compounds; Oxygen; Peroxynitrous Acid; Pulmonary Artery | 2011 |
Mechanistic investigations on the efficient catalytic decomposition of peroxynitrite by ebselen analogues.
Topics: Azoles; Carboxylic Acids; Catalysis; Crystallography, X-Ray; Hydrolysis; Isoindoles; Models, Molecular; Molecular Structure; Organoselenium Compounds; Peroxynitrous Acid; Stereoisomerism | 2011 |
Protective effect of diphenyl diselenide against peroxynitrite-mediated endothelial cell death: a comparison with ebselen.
Topics: Analysis of Variance; Animals; Aorta; Apoptosis; Azoles; Benzene Derivatives; Cattle; Cell Survival; Endothelial Cells; Glutathione; Glutathione Peroxidase; Isoindoles; NF-E2-Related Factor 2; Organoselenium Compounds; Peroxynitrous Acid; Protective Agents | 2013 |
Synthesis and evaluation of multi-target-directed ligands against Alzheimer's disease based on the fusion of donepezil and ebselen.
Topics: Acetylcholinesterase; Alzheimer Disease; Amyloid beta-Peptides; Animals; Azoles; Butyrylcholinesterase; Chemistry Techniques, Synthetic; Cholinesterase Inhibitors; Donepezil; Electrophorus; Glutathione Peroxidase; Humans; Indans; Isoindoles; Kinetics; Ligands; Mice; Molecular Docking Simulation; Molecular Targeted Therapy; Organoselenium Compounds; Peptide Fragments; Peroxynitrous Acid; Piperidines; Protein Multimerization; Protein Structure, Secondary; Thioredoxin-Disulfide Reductase; Toxicity Tests, Acute | 2013 |
Novel tacrine-ebselen hybrids with improved cholinesterase inhibitory, hydrogen peroxide and peroxynitrite scavenging activity.
Topics: Acetylcholinesterase; Animals; Azoles; Binding Sites; Butyrylcholinesterase; Cell Line; Cell Survival; Cholinesterase Inhibitors; Free Radical Scavengers; Horses; Humans; Hydrogen Peroxide; Isoindoles; Kinetics; Molecular Docking Simulation; Organoselenium Compounds; Peroxynitrous Acid; Protein Binding; Protein Structure, Tertiary; Tacrine | 2013 |
Intermittent Hypoxia-Induced Carotid Body Chemosensory Potentiation and Hypertension Are Critically Dependent on Peroxynitrite Formation.
Topics: Animals; Azoles; Blood Pressure; Carotid Body; Diastole; Hypertension; Hypoxia; Isoindoles; Male; Neuronal Plasticity; Organoselenium Compounds; Peroxynitrous Acid; Rats, Sprague-Dawley; Systole; Tyrosine | 2016 |
The Labile Iron Pool Reacts Rapidly and Catalytically with Peroxynitrite.
Topics: Aldehydes; Animals; Catalysis; Fluoresceins; Fluorescence; Hydrazones; Iron; Iron Chelating Agents; Isoindoles; Kinetics; Mice; Models, Biological; Nitric Oxide Donors; Organoselenium Compounds; Oxidation-Reduction; Paraquat; Peroxynitrous Acid; RAW 264.7 Cells | 2021 |