Page last updated: 2024-09-03

peroxynitrous acid and dinoprostone

peroxynitrous acid has been researched along with dinoprostone in 13 studies

Compound Research Comparison

Studies
(peroxynitrous acid)
Trials
(peroxynitrous acid)
Recent Studies (post-2010)
(peroxynitrous acid)
Studies
(dinoprostone)
Trials
(dinoprostone)
Recent Studies (post-2010) (dinoprostone)
3,303211,23029,1051,3466,357

Protein Interaction Comparison

ProteinTaxonomyperoxynitrous acid (IC50)dinoprostone (IC50)
Prostaglandin E2 receptor EP1 subtypeHomo sapiens (human)0.0155
Prostaglandin E2 receptor EP4 subtypeHomo sapiens (human)0.0031
Prostaglandin E2 receptor EP4 subtypeRattus norvegicus (Norway rat)0.0021
Prostaglandin E2 receptor EP3 subtypeHomo sapiens (human)0.002
Prostaglandin E2 receptor EP2 subtypeHomo sapiens (human)0.0087
Prostacyclin receptorHomo sapiens (human)0.26
Prostaglandin E2 receptor EP2 subtypeRattus norvegicus (Norway rat)0.0052

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's12 (92.31)29.6817
2010's1 (7.69)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Barrett, KE; Resta-Lenert, S1
Fakhrzadeh, L; Laskin, DL; Laskin, JD1
Beharka, AA; Meydani, SN; Serafini, M; Wu, D1
Beall, HD; Bunderson, M; Coffin, JD1
Deby-Dupont, G; Devel, P; Henrotin, Y; Martin, G; Mathy-Hartert, M; Pujol, JP; Reginster, JY1
Deeb, RS; Gamss, C; Hajjar, DP; Lindenbaum, R; Mittar, D; Resnick, MJ; Upmacis, RK1
Migita, K1
Armstrong, JS; Schantz, JT; Spencer, JP; Whiteman, M; Zhu, YZ1
Hwang, HJ; Kang, KJ; Lee, BH; Shin, HC1
Bachschmid, MM; Clavreul, N; Cohen, RA; Hou, X; Ido, Y; Idrizovic, A; Pimentel, D; Shi, C1
Hong, DH; Hwang, HJ; Kang, K; Kim, SH; Lee, BH; Park, Y; Shin, HC1
Cantoni, O; Cerioni, L; Palomba, L; Tommasini, I1
Chen, YJ; Quilley, J; Santos, M1

Reviews

1 review(s) available for peroxynitrous acid and dinoprostone

ArticleYear
[Nitric oxide in rheumatoid arthritis].
    Nihon rinsho. Japanese journal of clinical medicine, 2005, Volume: 63 Suppl 1

    Topics: Arthritis, Rheumatoid; Cyclooxygenase 2; Dinoprostone; Gene Expression Regulation, Enzymologic; Humans; Matrix Metalloproteinase 2; Membrane Proteins; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Peroxynitrous Acid; Prostaglandin-Endoperoxide Synthases; Synovial Membrane

2005

Other Studies

12 other study(ies) available for peroxynitrous acid and dinoprostone

ArticleYear
Enteroinvasive bacteria alter barrier and transport properties of human intestinal epithelium: role of iNOS and COX-2.
    Gastroenterology, 2002, Volume: 122, Issue:4

    Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Biological Transport; Caco-2 Cells; Chlorides; Cyclic AMP; Cyclic GMP; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Cystic Fibrosis Transmembrane Conductance Regulator; Diarrhea; Dinoprostone; Electric Impedance; Enzyme Inhibitors; Epithelial Cells; Escherichia coli Infections; Gene Expression Regulation, Enzymologic; Guanylate Cyclase; HT29 Cells; Humans; Intestinal Mucosa; Isoenzymes; Membrane Proteins; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrobenzenes; Peroxynitrous Acid; Prostaglandin-Endoperoxide Synthases; Salmonella Infections; Sodium-Potassium-Chloride Symporters; Solute Carrier Family 12, Member 2; Sulfonamides; Up-Regulation; Water-Electrolyte Balance

2002
Deficiency in inducible nitric oxide synthase protects mice from ozone-induced lung inflammation and tissue injury.
    American journal of respiratory cell and molecular biology, 2002, Volume: 26, Issue:4

    Topics: Administration, Inhalation; Animals; Bronchoalveolar Lavage Fluid; Cells, Cultured; Dinoprostone; Female; Interferon-gamma; Lipopolysaccharides; Lung; Macrophages, Alveolar; Mice; Mice, Inbred Strains; Mice, Knockout; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Oxidants, Photochemical; Ozone; Peroxynitrous Acid; Pneumonia; Superoxides; Tyrosine

2002
Mechanism of vitamin E inhibition of cyclooxygenase activity in macrophages from old mice: role of peroxynitrite.
    Free radical biology & medicine, 2002, Mar-15, Volume: 32, Issue:6

    Topics: Aging; Animals; Antioxidants; Cyclooxygenase 2; Dinoprostone; Isoenzymes; Macrophages; Male; Mice; Mice, Inbred C57BL; Nitric Oxide; Peroxynitrous Acid; Prostaglandin-Endoperoxide Synthases; Superoxides; Vitamin E

2002
Arsenic induces peroxynitrite generation and cyclooxygenase-2 protein expression in aortic endothelial cells: possible role in atherosclerosis.
    Toxicology and applied pharmacology, 2002, Oct-01, Volume: 184, Issue:1

    Topics: Animals; Aorta; Arsenic; Arteriosclerosis; Cattle; Cell Survival; Cells, Cultured; Cyclooxygenase 2; Dinoprostone; Dose-Response Relationship, Drug; Endothelium; Gene Expression Regulation, Enzymologic; Isoenzymes; Peroxynitrous Acid; Prostaglandin-Endoperoxide Synthases

2002
Reactive oxygen species downregulate the expression of pro-inflammatory genes by human chondrocytes.
    Inflammation research : official journal of the European Histamine Research Society ... [et al.], 2003, Volume: 52, Issue:3

    Topics: Cartilage, Articular; Cell Survival; Chondrocytes; Dinoprostone; DNA; DNA Fragmentation; Down-Regulation; Humans; In Vitro Techniques; Inflammation; Interleukin-1; Interleukin-6; Interleukin-8; L-Lactate Dehydrogenase; Lipopolysaccharides; Nitric Oxide; Osteoarthritis; Peroxynitrous Acid; Reactive Oxygen Species; Reverse Transcriptase Polymerase Chain Reaction

2003
Involvement of the mitogen-activated protein kinase cascade in peroxynitrite-mediated arachidonic acid release in vascular smooth muscle cells.
    American journal of physiology. Cell physiology, 2004, Volume: 286, Issue:6

    Topics: Animals; Arachidonic Acid; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Chelating Agents; Dinoprostone; Enzyme Inhibitors; Group IV Phospholipases A2; MAP Kinase Signaling System; Mitogen-Activated Protein Kinases; Molsidomine; Muscle, Smooth, Vascular; Nitric Oxide; p38 Mitogen-Activated Protein Kinases; Peroxynitrous Acid; Phospholipases A; Rats

2004
Peroxynitrite-modified collagen-II induces p38/ERK and NF-kappaB-dependent synthesis of prostaglandin E2 and nitric oxide in chondrogenically differentiated mesenchymal progenitor cells.
    Osteoarthritis and cartilage, 2006, Volume: 14, Issue:5

    Topics: Arthritis; Cell Differentiation; Cells, Cultured; Collagen Type II; Cyclooxygenase 2; Dinoprostone; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Humans; Membrane Proteins; Mesenchymal Stem Cells; Mitogen-Activated Protein Kinases; NF-kappa B; Nitric Oxide; Nitric Oxide Synthase Type II; p38 Mitogen-Activated Protein Kinases; Peroxynitrous Acid; Phosphorylation

2006
An antioxidative and antiinflammatory agent for potential treatment of osteoarthritis from Ecklonia cava.
    Archives of pharmacal research, 2006, Volume: 29, Issue:2

    Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Cartilage, Articular; Cell Line; Dinoprostone; Free Radical Scavengers; Lipopolysaccharides; Lipoproteins, LDL; Macrophages; Mice; Osteoarthritis; Peroxynitrous Acid; Phaeophyceae; Proteoglycans; Rabbits; Seaweed; Tannins

2006
S-glutathiolation of p21ras by peroxynitrite mediates endothelial insulin resistance caused by oxidized low-density lipoprotein.
    Arteriosclerosis, thrombosis, and vascular biology, 2006, Volume: 26, Issue:11

    Topics: Alprostadil; Animals; Aorta; Cattle; Dinoprostone; Endothelial Cells; Endothelium, Vascular; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Glutathione; Glutathione Disulfide; Insulin; Insulin Receptor Substrate Proteins; Insulin Resistance; Lipoproteins, LDL; Lysophosphatidylcholines; Oncogene Protein p21(ras); Oxidants; Peroxynitrous Acid; Phosphoproteins; Phosphorylation; Prostaglandins E, Synthetic; Signal Transduction

2006
Antioxidant and antiinflammatory activities of ventol, a phlorotannin-rich natural agent derived from Ecklonia cava, and its effect on proteoglycan degradation in cartilage explant culture.
    Research communications in molecular pathology and pharmacology, 2004, Volume: 115-116

    Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Cartilage, Articular; Cell Line; Culture Media; Dinoprostone; Dioxins; Dose-Response Relationship, Drug; Free Radical Scavengers; Glycosaminoglycans; Humans; Interleukin-1alpha; Lipoproteins, LDL; Macrophages, Peritoneal; Mice; Molecular Structure; Organ Culture Techniques; Oxidation-Reduction; Peroxynitrous Acid; Phaeophyceae; Phenols; Proteoglycans; Rabbits; Recombinant Proteins

2004
Prostaglandin E2 signals monocyte/macrophage survival to peroxynitrite via protein kinase A converging in bad phosphorylation with the protein kinase C alpha-dependent pathway driven by 5-hydroxyeicosatetraenoic acid.
    Journal of immunology (Baltimore, Md. : 1950), 2008, Oct-15, Volume: 181, Issue:8

    Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; bcl-Associated Death Protein; Cell Death; Cell Survival; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dinoprostone; Enzyme Activation; Humans; Hydroxyeicosatetraenoic Acids; Inflammation; Macrophages, Peritoneal; Mitochondrial Proteins; Monocytes; Peroxynitrous Acid; Phospholipase A2 Inhibitors; Phospholipases A2; Phosphorylation; Protein Kinase C-alpha; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP2 Subtype; Signal Transduction; U937 Cells

2008
Treatment of diabetic rats with a peroxynitrite decomposition catalyst prevents induction of renal COX-2.
    American journal of physiology. Heart and circulatory physiology, 2011, Volume: 300, Issue:3

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Arachidonic Acid; Cells, Cultured; Creatinine; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Diabetes Mellitus, Experimental; Dinoprostone; Humans; Kidney; Male; Metalloporphyrins; Peroxynitrous Acid; Rats; Rats, Wistar; Transforming Growth Factor beta; Tumor Necrosis Factor-alpha; Tyrosine

2011