peroxynitrous acid has been researched along with cysteine in 64 studies
| Studies (peroxynitrous acid) | Trials (peroxynitrous acid) | Recent Studies (post-2010) (peroxynitrous acid) | Studies (cysteine) | Trials (cysteine) | Recent Studies (post-2010) (cysteine) |
|---|---|---|---|---|---|
| 3,303 | 21 | 1,230 | 40,132 | 418 | 11,457 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 41 (64.06) | 29.6817 |
| 2010's | 22 (34.38) | 24.3611 |
| 2020's | 1 (1.56) | 2.80 |
| Authors | Studies |
|---|---|
| Stadtman, ER | 1 |
| Ferrer, JV; Javitch, JA; Kuhn, DM; Park, SU | 1 |
| Kocis, JM; Kuo, WN | 1 |
| Josephs, M; Katan, M; Rodrigues-Lima, F | 1 |
| Augusto, O; Denicola, A; Linares, E; Lopes de Menezes, S; Radi, R; Romero, N | 1 |
| Bennett, BM; Ji, Y | 1 |
| Bauer, JA; Mihm, MJ | 1 |
| Kil, IS; Kim, SY; Lee, JH; Park, JW; Yang, ES | 1 |
| Atmane, N; Dairou, J; Dupret, JM; Rodrigues-Lima, F | 1 |
| Grosclaude, J; Guermonprez, L; Morot-Gaudry-Talarmain, Y; Rezaei, H; Treguer, E | 1 |
| Kennett, KL; Landino, LM; Moynihan, KL; Todd, JV | 1 |
| Budde, H; Flohé, L; Piñeyro, MD; Radi, R; Robello, C; Stehr, M; Trujillo, M | 1 |
| Alston, JA; Landino, LM; Skreslet, TE | 1 |
| Abramson, SB; Clancy, RM; Gomez, PF | 1 |
| Bryan-Lluka, LJ; Paczkowski, FA; Papacostas, MH; Wanstall, JC | 1 |
| Cabral, DM; Landino, LM; Robinson, SH; Skreslet, TE | 1 |
| Alves, MJ; Augusto, O; Fernandes, DC; Medinas, DB | 1 |
| Angeletti, M; Eleuteri, AM; Fioretti, E; Lupidi, G; Montecchia, F; Pucciarelli, S; Spina, M | 1 |
| Nowak, P; Olas, B; Wachowicz, B | 1 |
| Amendola, D; Boffi, A; Fontana, M; Orsini, E; Pecci, L | 1 |
| Aguilera, R; Cadenas, E; Canali, R; Gallaher, TK; Garcia, J; Han, D | 1 |
| Ide, N; Kyo, E; Morihara, N; Sumioka, I | 1 |
| Bates, JN; Graves, JE; Kooy, NW; Lewis, SJ | 2 |
| Graves, JE; Kooy, NW; Lewis, SJ | 1 |
| Adachi, T; Clavreul, N; Cohen, RA; Ido, Y; Pimental, DR; Schöneich, C | 1 |
| Aureliano, M; Gutiérrez-Merino, C; Martín-Romero, FJ; Simão, S; Tiago, T | 1 |
| Deeb, RS; Hajjar, DP; Upmacis, RK | 1 |
| Chang, N; Chun, HS; Kim, JM; Kim, WK; Lee, JC | 1 |
| Medina-Campos, ON; Pedraza-Chaverrí, J; Segoviano-Murillo, S | 1 |
| Duprè, S; Fontana, M; Pecci, L | 1 |
| Augusto, O; Munhoz, DC; Netto, LE; Ogusucu, R; Rettori, D | 1 |
| Clavreul, N; Cohen, RA; Costello, CE; Huang, H; McComb, ME; Sethuraman, M | 1 |
| Ferrer-Sueta, G; Flohé, L; Radi, R; Thomson, L; Trujillo, M | 1 |
| Castellano, I; Cecere, F; Chambery, A; De Vendittis, E; Di Maro, A; Masullo, M; Michniewicz, A; Parlato, G; Ruocco, MR | 1 |
| Fontana, M; Giovannitti, F; Pecci, L | 1 |
| Asatryan, L; Gallaher, TK; Hamilton, RT; Hsiai, TK; Isas, JM; Nilsen, JT; Sawamura, T | 1 |
| Dremina, ES; Galeva, NA; Schöneich, C; Sharov, VS; Williams, TD | 1 |
| Bhattacharya, SC; Priyam, A; Saha, A | 1 |
| Bibert, S; Chia, KK; Cornelius, F; Figtree, GA; Garcia, A; Geering, K; Hamilton, EJ; Liu, CC; Rasmussen, HH; White, CN | 1 |
| Alvarez, B; Botti, H; Hugo, M; Manta, B; Monteiro, G; Netto, LE; Radi, R; Trujillo, M; Turell, L | 1 |
| Chen, CL; Chen, YR; Garg, V; Green-Church, KB; Hu, K; Kang, PT; Zhang, L | 1 |
| Barroso, JB; Carreras, A; Pedrajas, JR; Valderrama, R | 1 |
| Cozza, G; Flohé, L; Toppo, S; Ursini, F | 1 |
| Kolodziejczyk, J; Saluk-Juszczak, J; Wachowicz, B | 1 |
| Burgoyne, JR; Eaton, P; Mayr, M; Rudyk, O | 1 |
| Audi, R; Augusto, O; Monteiro, G; Netto, LE; Ogusucu, R; Toledo, JC | 1 |
| Bai, X; Fan, Z; Han, Y; Li, J; Liu, W; Lu, S; Wang, H; Wang, X; Xin, H; Xu, W; Zhang, G | 1 |
| Hugo, M; Jacquot, JP; Radi, R; Rouhier, N; Selles, B; Srivastava, V; Trujillo, M; Wingsle, G | 1 |
| Niemann, J; Tsikas, D | 1 |
| Thurmond, DC; Wiseman, DA | 1 |
| Chen, HJ; Chen, YC | 1 |
| Kawafune, H; Komatsubara, AT; Kyotani, Y; Nishimura, Y; Ozawa, K; Sawada, T; Takahashi, R; Tanaka, T; Tsuji, Y; Tsumoto, H; Yoshizumi, M; Zhao, J | 1 |
| Estrin, DA; González Lebrero, MC; Radi, R; Trujillo, M; Zeida, A | 1 |
| Batthyány, C; Buschiazzo, A; Demicheli, V; Durán, R; Hugo, M; Larrieux, N; Lima, A; Martí, MA; Martinez, A; Moreno, DM; Peluffo, G; Petruk, AA; Piacenza, L; Piñeyro, D; Radi, R; Robello, C; Trujillo, M | 1 |
| Binno, SM; Cabassi, A; Coghi, P; Dancelli, S; de Champlain, J; Fiaccadori, E; Govoni, P; Montanari, A; Piepoli, M; Regolisti, G; Rocco, R; Ruzicka, V; Tedeschi, S; Vicini, V | 1 |
| Cao, DJ; Hill, JA | 1 |
| Alvarez, C; Celedón, G; Gonzalez, G; Lanio, ME; León, L; Lissi, EA; Pazos, F | 1 |
| Adamus, J; Dębski, D; Kalyanaraman, B; Marcinek, A; Michałowski, B; Sikora, A; Smulik, R; Zielonka, J | 1 |
| Akbarali, HI; Gade, A; Hashimoto, A; Kang, M | 1 |
| Fitzpatrick, J; Kim, E | 1 |
| Feng, GG; Fujiwara, Y; Hayashi, H; Kinoshita, H; Li, J; Nakamura, E; Sato, M; Yasuda, Y | 1 |
| Alegria, TGP; De Armas, MI; Esteves, R; Mastrogiovanni, M; Netto, LES; Radi, R; Reyes, AM; Tórtora, V; Trujillo, M; Viera, N | 1 |
| Li, P; Nie, J; Tang, B; Wang, H; Wang, Y; Zhang, W; Zhang, X | 1 |
5 review(s) available for peroxynitrous acid and cysteine
| Article | Year |
|---|---|
Protein oxidation in aging and age-related diseases.
Topics: Aging; Amino Acids; Animals; Antioxidants; Apoptosis; Cross-Linking Reagents; Cysteine; Disease; Humans; Longevity; Methionine; Models, Biological; Nitric Oxide; Oxidants; Oxidation-Reduction; Oxidative Stress; Peptides; Peroxynitrous Acid; Protein Denaturation; Proteins; Rats; Reactive Oxygen Species; Tyrosine | 2001 |
Oxidative alterations of cyclooxygenase during atherogenesis.
Topics: Animals; Arachidonic Acid; Atherosclerosis; Cyclooxygenase Inhibitors; Cysteine; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Enzyme Activation; Heme; Humans; Intramolecular Oxidoreductases; MAP Kinase Signaling System; Nitric Oxide; Nitrogen Oxides; Oxidation-Reduction; Peroxynitrous Acid; Prostaglandin-Endoperoxide Synthases; Tyrosine | 2006 |
Kinetics of peroxiredoxins and their role in the decomposition of peroxynitrite.
Topics: Amino Acid Motifs; Animals; Catalysis; Catalytic Domain; Cysteine; Disulfides; Humans; Kinetics; Metalloproteins; Oxidation-Reduction; Peroxides; Peroxiredoxins; Peroxynitrous Acid; Protein Structure, Quaternary; Substrate Specificity; Sulfenic Acids | 2007 |
A comparison of thiol peroxidase mechanisms.
Topics: Catalysis; Catalytic Domain; Cysteine; Glutathione Peroxidase; Hydrogen Peroxide; Oxidation-Reduction; Peroxiredoxins; Peroxynitrous Acid; Protein Conformation; Selenocysteine; Signal Transduction; Sulfhydryl Compounds | 2011 |
The good and bad effects of cysteine S-nitrosylation and tyrosine nitration upon insulin exocytosis: a balancing act.
Topics: Apoptosis; Cyclic GMP; Cysteine; Diabetes Mellitus; Exocytosis; Female; Humans; Insulin-Secreting Cells; Male; Nitric Oxide; Oxidation-Reduction; Peroxynitrous Acid; Protein Processing, Post-Translational; Signal Transduction; Tyrosine | 2012 |
59 other study(ies) available for peroxynitrous acid and cysteine
| Article | Year |
|---|---|
Peroxynitrite inactivates the human dopamine transporter by modification of cysteine 342: potential mechanism of neurotoxicity in dopamine neurons.
Topics: Antioxidants; Biological Transport; Biotin; Cell Line; Cysteine; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dose-Response Relationship, Drug; Free Radical Scavengers; Humans; Kidney; Membrane Glycoproteins; Membrane Transport Modulators; Membrane Transport Proteins; Mutagenesis, Site-Directed; Nerve Tissue Proteins; Neurons; Neurotoxicity Syndromes; Peroxynitrous Acid; Structure-Activity Relationship; Substrate Specificity; Sulfhydryl Reagents; Transfection | 2002 |
Nitration/S-nitrosation of proteins by peroxynitrite-treatment and subsequent modification by glutathione S-transferase and glutathione peroxidase.
Topics: Animals; Blotting, Western; Cattle; Cysteine; Electrophoresis, Polyacrylamide Gel; Glutathione; Glutathione Peroxidase; Glutathione Transferase; Hemoglobins; Histones; Horses; In Vitro Techniques; Mice; Nitrosation; Oxidative Stress; Peroxynitrous Acid; S-Nitrosothiols; Tyrosine | 2002 |
Irreversible inactivation of magnesium-dependent neutral sphingomyelinase 1 (NSM1) by peroxynitrite, a nitric oxide-derived oxidant.
Topics: Animals; Cysteine; Dose-Response Relationship, Drug; Enzyme Inhibitors; Hydrogen Peroxide; Magnesium; Mice; Molsidomine; Nitric Oxide; Nitric Oxide Donors; Oxidants; Oxidative Stress; Peroxynitrous Acid; Reducing Agents; Sphingomyelin Phosphodiesterase | 2002 |
EPR detection of glutathiyl and hemoglobin-cysteinyl radicals during the interaction of peroxynitrite with human erythrocytes.
Topics: Cyclic N-Oxides; Cysteine; Electron Spin Resonance Spectroscopy; Erythrocytes; Free Radicals; Glutathione; Hemoglobins; Humans; Oxidants; Oxidation-Reduction; Peroxynitrous Acid; Spin Labels; Tyrosine | 2002 |
Activation of microsomal glutathione s-transferase by peroxynitrite.
Topics: Animals; Cysteine; Enzyme Activation; Glutathione Transferase; Hydrogen Peroxide; Imidazoles; Male; Microsomes, Liver; Nitrates; Peptide Fragments; Peroxynitrous Acid; Rats; Rats, Sprague-Dawley; Tetranitromethane; Tyrosine | 2003 |
Peroxynitrite-induced inhibition and nitration of cardiac myofibrillar creatine kinase.
Topics: Blotting, Western; Creatine Kinase; Cysteine; Dose-Response Relationship, Drug; Kinetics; Myocardium; Myofibrils; Nitrates; Peroxynitrous Acid; Reactive Nitrogen Species; Tyrosine | 2002 |
Human sensitive to apoptosis gene protein inhibits peroxynitrite-induced DNA damage.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Antioxidants; Cysteine; Deoxyguanosine; DNA Damage; Dose-Response Relationship, Drug; Ethylmaleimide; Humans; Molsidomine; Peroxynitrous Acid; RNA-Binding Proteins; Sulfhydryl Reagents; Ubiquitin-Protein Ligases | 2003 |
Peroxynitrite irreversibly inactivates the human xenobiotic-metabolizing enzyme arylamine N-acetyltransferase 1 (NAT1) in human breast cancer cells: a cellular and mechanistic study.
Topics: Arylamine N-Acetyltransferase; Breast Neoplasms; Cysteine; Dithiothreitol; Enzyme Inhibitors; Glutathione; Humans; Isoenzymes; Kinetics; Molsidomine; Oxidation-Reduction; Peroxynitrous Acid; Recombinant Proteins; Tumor Cells, Cultured | 2004 |
Selective prion protein binding to synaptic components is modulated by oxidative and nitrosative changes induced by copper(II) and peroxynitrite in cholinergic synaptosomes, unveiling a role for calcineurin B and thioredoxin.
Topics: 14-3-3 Proteins; Animals; Blotting, Western; Calcineurin; Carbocyanines; Choline O-Acetyltransferase; Copper Sulfate; Cyclophilin A; Cysteine; Dose-Response Relationship, Drug; Epitopes; Humans; In Vitro Techniques; Membrane Glycoproteins; Membrane Proteins; Mercaptoethanol; Nerve Tissue Proteins; Neurons; Nitrosation; Oxidation-Reduction; Peroxynitrous Acid; Prions; Protein Binding; Pyruvic Acid; Qa-SNARE Proteins; R-SNARE Proteins; Recombinant Proteins; S-Nitrosothiols; Sheep; Synapsins; Synaptic Vesicles; Synaptosomes; Tacrolimus Binding Proteins; Thioredoxins; Time Factors; Torpedo; Tyrosine; Tyrosine 3-Monooxygenase | 2003 |
Modulation of the redox state of tubulin by the glutathione/glutaredoxin reductase system.
Topics: Animals; Blotting, Western; Brain; Chromatography, High Pressure Liquid; Coloring Agents; Cysteine; Cystine; Disulfides; Dose-Response Relationship, Drug; Escherichia coli; Fluoresceins; Glutaredoxins; Glutathione; Glutathione Reductase; Humans; Hydrogen-Ion Concentration; Models, Chemical; Oxidation-Reduction; Oxidoreductases; Oxygen; Peroxynitrous Acid; Proteins; Swine; Time Factors; Tubulin | 2004 |
Trypanosoma brucei and Trypanosoma cruzi tryparedoxin peroxidases catalytically detoxify peroxynitrite via oxidation of fast reacting thiols.
Topics: Animals; Catalysis; Cysteine; Cytosol; Dose-Response Relationship, Drug; Electrons; Glutathione; Hydrogen-Ion Concentration; Kinetics; Macrophages; Manganese; Models, Chemical; Oxygen; Peroxidases; Peroxynitrous Acid; Porphyrins; Protozoan Proteins; Spermidine; Sulfhydryl Compounds; Temperature; Time Factors; Trypanosoma brucei brucei; Trypanosoma cruzi | 2004 |
Cysteine oxidation of tau and microtubule-associated protein-2 by peroxynitrite: modulation of microtubule assembly kinetics by the thioredoxin reductase system.
Topics: Animals; Blotting, Western; Brain; Cysteine; Disulfides; Escherichia coli; Fluoresceins; Humans; Kinetics; MAP Kinase Signaling System; Microtubule-Associated Proteins; Microtubules; Models, Chemical; Oxidation-Reduction; Oxygen; Peroxynitrous Acid; Swine; tau Proteins; Temperature; Thioredoxin-Disulfide Reductase; Thioredoxins; Time Factors | 2004 |
Nitric oxide sustains nuclear factor kappaB activation in cytokine-stimulated chondrocytes.
Topics: Animals; Cattle; Cells, Cultured; Chondrocytes; Cysteine; Cytokines; Cytosol; Enzyme Inhibitors; Fluorescent Antibody Technique; Free Radical Scavengers; Immunoblotting; NF-kappa B; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitroso Compounds; omega-N-Methylarginine; Peroxynitrous Acid; Reverse Transcriptase Polymerase Chain Reaction | 2004 |
Nitric oxide donors inhibit 5-hydroxytryptamine (5-HT) uptake by the human 5-HT transporter (SERT).
Topics: Animals; Biological Transport; Catalase; Chlorocebus aethiops; COS Cells; Culture Media; Cysteine; DNA, Complementary; Dose-Response Relationship, Drug; Enzyme Inhibitors; Free Radical Scavengers; Guanylate Cyclase; Humans; Hydroxocobalamin; Membrane Glycoproteins; Membrane Transport Modulators; Membrane Transport Proteins; Nerve Tissue Proteins; Nitric Oxide Donors; Nitro Compounds; Oxadiazoles; Peroxynitrous Acid; Piperazines; Quinoxalines; Serotonin; Serotonin Plasma Membrane Transport Proteins; Superoxide Dismutase; Transfection | 2004 |
Redox modulation of tau and microtubule-associated protein-2 by the glutathione/glutaredoxin reductase system.
Topics: Animals; Brain; Chromatography, High Pressure Liquid; Cysteine; Disulfides; Dose-Response Relationship, Drug; Escherichia coli; Fluoresceins; Glutaredoxins; Glutathione; Glutathione Reductase; Humans; Hydrogen Peroxide; Microtubule-Associated Proteins; Microtubules; Models, Chemical; NADP; Oxidants; Oxidation-Reduction; Oxidoreductases; Oxygen; Peroxynitrous Acid; Sulfhydryl Compounds; Swine; tau Proteins; Time Factors | 2004 |
Tempol diverts peroxynitrite/carbon dioxide reactivity toward albumin and cells from protein-tyrosine nitration to protein-cysteine nitrosation.
Topics: Albumins; Animals; Antioxidants; Catalysis; Cyclic N-Oxides; Cysteine; Electrochemistry; Electron Spin Resonance Spectroscopy; Free Radical Scavengers; Free Radicals; Immunoblotting; Immunohistochemistry; Inflammation; Macrophages; Mice; Models, Biological; Models, Chemical; Nitric Oxide; Nitrites; Nitrogen; Oxygen; Peroxynitrous Acid; Serum Albumin, Bovine; Spin Labels; Time Factors; Tyrosine | 2005 |
Peroxynitrite-mediated oxidation of the C85S/C152E mutant of dihydrofolate reductase from Escherichia coli: functional and structural effects.
Topics: Blotting, Western; Calorimetry, Differential Scanning; Chromatography, Gel; Chromatography, High Pressure Liquid; Cysteine; Cystine; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Immunoblotting; Mutation; Oxidative Stress; Oxygen; Peroxynitrous Acid; Reactive Oxygen Species; Spectrometry, Fluorescence; Temperature; Tetrahydrofolate Dehydrogenase; Thermodynamics; Time Factors; Tryptophan; Tyrosine | 2005 |
Resveratrol protects against peroxynitrite-induced thiol oxidation in blood platelets.
Topics: Antioxidants; Blood Platelets; Cysteine; Dipeptides; Glutathione; Humans; Oxidation-Reduction; Oxidative Stress; Peroxynitrous Acid; Resveratrol; Stilbenes; Sulfhydryl Compounds | 2004 |
Oxidation of hypotaurine and cysteine sulphinic acid by peroxynitrite.
Topics: Bicarbonates; Cysteine; Hydrogen-Ion Concentration; Kinetics; Oxidants; Oxidation-Reduction; Oxygen; Peroxynitrous Acid; Sulfates; Sulfinic Acids; Taurine | 2005 |
Sites and mechanisms of aconitase inactivation by peroxynitrite: modulation by citrate and glutathione.
Topics: Aconitate Hydratase; Amino Acid Sequence; Amino Acids; Animals; Citric Acid; Cysteine; Enzyme Activation; Glutathione; Mass Spectrometry; Molecular Sequence Data; Myocardium; Peroxynitrous Acid; Swine; Tyrosine | 2005 |
Aged garlic extract inhibits peroxynitrite-induced hemolysis.
Topics: Animals; Antineoplastic Agents; Cysteine; Dose-Response Relationship, Drug; Erythrocytes; Garlic; Hemolysis; Male; Nitric Oxide; Nitric Oxide Synthase; Oxidative Stress; Peroxynitrous Acid; Plant Extracts; Rats; Rats, Wistar; Superoxides | 2005 |
Peroxynitrite elicits dysfunction of stereoselective s-nitrosocysteine recognition sites.
Topics: Animals; Binding Sites; Cysteine; Dose-Response Relationship, Drug; Hemodynamics; Male; Nitric Oxide Donors; Peroxynitrous Acid; Rats; Rats, Sprague-Dawley; S-Nitrosothiols; Stereoisomerism; Tachyphylaxis; Vascular Resistance; Vasodilator Agents | 2005 |
Role of ATP-sensitive K+ -channels in hemodynamic effects of peroxynitrite in anesthetized rats.
Topics: Adenosine Triphosphate; Anesthesia; Animals; Blood Pressure; Cromakalim; Cysteine; Dose-Response Relationship, Drug; Glyburide; Hemodynamics; Male; Peroxynitrous Acid; Potassium Channel Blockers; Potassium Channels; Rats; Rats, Sprague-Dawley; S-Nitrosothiols; Vascular Resistance | 2005 |
S-glutathiolation by peroxynitrite of p21ras at cysteine-118 mediates its direct activation and downstream signaling in endothelial cells.
Topics: Acetophenones; Androstadienes; Animals; Aorta; Butadienes; Cattle; Cells, Cultured; Cysteine; Endothelial Cells; Endothelium, Vascular; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Glutathione; Guanosine Diphosphate; Lipoproteins, LDL; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitriles; Oxidation-Reduction; Peroxynitrous Acid; Phosphorylation; Protein Processing, Post-Translational; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins p21(ras); Recombinant Fusion Proteins; Signal Transduction; Wortmannin | 2006 |
Vasodilator actions of the endothelium-derived relaxing factor L-S-nitrosocysteine in anaesthetized rats are markedly diminished by peroxynitrite.
Topics: Anesthesia; Animals; Blood Pressure; Cysteine; Dose-Response Relationship, Drug; Hemodynamics; Hydrazines; Male; Muscle, Smooth, Vascular; Nitric Oxide Donors; Peroxynitrous Acid; Rats; Rats, Sprague-Dawley; S-Nitrosothiols; Tachyphylaxis; Vasodilator Agents | 2005 |
Inhibition of skeletal muscle S1-myosin ATPase by peroxynitrite.
Topics: Actins; Adenosine Diphosphate; Adenosine Triphosphatases; Animals; Catalysis; Cysteine; Dose-Response Relationship, Drug; Enzyme Stability; Magnesium; Molsidomine; Myosin Subfragments; Oxidation-Reduction; Peroxynitrous Acid; Protein Folding; Rabbits; Skeletal Muscle Myosins; Temperature; Time Factors; Tyrosine | 2006 |
S-Allyl-L-cysteine attenuates cerebral ischemic injury by scavenging peroxynitrite and inhibiting the activity of extracellular signal-regulated kinase.
Topics: Animals; Antioxidants; Brain; Brain Ischemia; Cysteine; Dose-Response Relationship, Drug; Enzyme Inhibitors; Extracellular Signal-Regulated MAP Kinases; Gerbillinae; Male; Mitochondria; Neuroglia; Peroxynitrous Acid; Rats; Rats, Sprague-Dawley | 2006 |
Effect of heating on peroxynitrite scavenging capacity of garlic.
Topics: Cysteine; Free Radical Scavengers; Garlic; Hot Temperature; Masoprocol; Peroxynitrous Acid; Plant Extracts | 2007 |
The reactivity of hypotaurine and cysteine sulfinic acid with peroxynitrite.
Topics: Animals; Cysteine; Humans; Hydrogen-Ion Concentration; Nitrates; Nitrites; Oxidation-Reduction; Oxygen; Peroxynitrous Acid; Sulfinic Acids; Taurine | 2006 |
Reactions of yeast thioredoxin peroxidases I and II with hydrogen peroxide and peroxynitrite: rate constants by competitive kinetics.
Topics: Amino Acid Sequence; Cysteine; Horseradish Peroxidase; Hydrogen Peroxide; Kinetics; Molecular Sequence Data; Peroxidases; Peroxiredoxins; Peroxynitrous Acid; Saccharomyces cerevisiae Proteins; Sequence Homology, Amino Acid | 2007 |
Quantification of oxidative posttranslational modifications of cysteine thiols of p21ras associated with redox modulation of activity using isotope-coded affinity tags and mass spectrometry.
Topics: Amino Acid Sequence; Chromatography, Liquid; Cysteine; Free Radicals; Glutathione; Humans; Mass Spectrometry; Molecular Sequence Data; Oxidation-Reduction; Oxygen; Peroxynitrous Acid; Protein Processing, Post-Translational; Proto-Oncogene Proteins p21(ras); Spectrometry, Mass, Electrospray Ionization; Sulfhydryl Compounds | 2007 |
Glutathionylation of the iron superoxide dismutase from the psychrophilic eubacterium Pseudoalteromonas haloplanktis.
Topics: Chromatography, High Pressure Liquid; Cysteine; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Escherichia coli; Eubacterium; Glutathione; Mass Spectrometry; Mutant Proteins; Peroxynitrous Acid; Pseudoalteromonas; Recombinant Proteins; Superoxide Dismutase; Tyrosine | 2008 |
The protective effect of hypotaurine and cysteine sulphinic acid on peroxynitrite-mediated oxidative reactions.
Topics: Antioxidants; Cysteine; Dimerization; Dose-Response Relationship, Drug; Glutathione; Humans; Models, Chemical; Nitrites; Oxidation-Reduction; Oxygen; Oxygen Consumption; Peroxynitrous Acid; Rhodamines; Taurine; Tyrosine | 2008 |
LDL protein nitration: implication for LDL protein unfolding.
Topics: Animals; Aorta; Apolipoprotein B-100; Cattle; Cells, Cultured; Cysteine; Dose-Response Relationship, Drug; Endothelial Cells; Endothelium, Vascular; Humans; Lipid Peroxidation; Lipid Peroxides; Lipoproteins, LDL; Models, Chemical; Molsidomine; Oxidation-Reduction; Peroxynitrous Acid; Protein Conformation; Protein Denaturation; Protein Processing, Post-Translational; Protein Structure, Secondary; Proteins; Reproducibility of Results; Tyrosine | 2008 |
Inactivation of rabbit muscle glycogen phosphorylase b by peroxynitrite revisited: does the nitration of Tyr613 in the allosteric inhibition site control enzymatic function?
Topics: Allosteric Site; Amino Acid Sequence; Animals; Cysteine; Glycogen Phosphorylase, Muscle Form; Kinetics; Models, Molecular; Molecular Sequence Data; Muscle, Skeletal; Nitrates; Peptide Fragments; Peroxynitrous Acid; Protein Conformation; Rabbits; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Trypsin; Tyrosine | 2009 |
Volatile interface of biological oxidant and luminescent CdTe quantum dots: implications in nanodiagnostics.
Topics: Absorption; Cadmium; Cysteine; Luminescence; Oxidation-Reduction; Particle Size; Peroxynitrous Acid; Quantum Dots; Tellurium | 2009 |
Reversible oxidative modification: a key mechanism of Na+-K+ pump regulation.
Topics: Adenosine Triphosphatases; Angiotensin II; Animals; Cation Transport Proteins; Cell Adhesion Molecules, Neuronal; Cysteine; Glutaredoxins; Glutathione; Humans; Kidney; Kinetics; Male; Mutation; Myocytes, Cardiac; NADPH Oxidases; Oocytes; Oxidation-Reduction; Paraquat; Peroxynitrous Acid; Protein Conformation; Protein Kinase C; Protein Processing, Post-Translational; Rabbits; Sheep; Signal Transduction; Sodium-Potassium-Exchanging ATPase; Structure-Activity Relationship; Superoxide Dismutase; Swine; Xenopus laevis | 2009 |
Thiol and sulfenic acid oxidation of AhpE, the one-cysteine peroxiredoxin from Mycobacterium tuberculosis: kinetics, acidity constants, and conformational dynamics.
Topics: Antioxidants; Cysteine; Humans; Hydrogen-Ion Concentration; Kinetics; Mycobacterium tuberculosis; Oxidation-Reduction; Peroxides; Peroxiredoxins; Peroxynitrous Acid; Protein Conformation; Substrate Specificity; Sulfenic Acids; Sulfhydryl Compounds; Thermodynamics | 2009 |
Peroxynitrite-mediated oxidative modifications of complex II: relevance in myocardial infarction.
Topics: Amino Acid Sequence; Animals; Cell Hypoxia; Cyclic N-Oxides; Cysteine; Disulfides; Electron Transport Complex II; Flavin-Adenine Dinucleotide; Humans; Molecular Sequence Data; Molecular Weight; Muscle Cells; Myocardial Infarction; Oxidation-Reduction; Peroxynitrous Acid; Protein Subunits; Rats; Rats, Sprague-Dawley; Tyrosine | 2010 |
Mitochondrial 1-Cys-peroxiredoxin/thioredoxin system protects manganese-containing superoxide dismutase (Mn-SOD) against inactivation by peroxynitrite in Saccharomyces cerevisiae.
Topics: Cysteine; Manganese; Mitochondria; Nitric Oxide; Peroxiredoxins; Peroxynitrous Acid; Saccharomyces cerevisiae; Structure-Activity Relationship; Superoxide Dismutase; Thioredoxins | 2010 |
L-Carnitine protects plasma components against oxidative alterations.
Topics: Adult; Antioxidants; Blood Proteins; Carnitine; Cysteine; Dietary Supplements; Glutathione; Homocysteine; Humans; Lipid Peroxides; Lipids; Male; Osmolar Concentration; Oxidants; Oxidation-Reduction; Oxidative Stress; Peroxynitrous Acid; Protein Carbonylation; Thiobarbituric Acid Reactive Substances; Tyrosine; Young Adult | 2011 |
Nitrosative protein oxidation is modulated during early endotoxemia.
Topics: Animals; Biotin; Blood Pressure; Cysteine; Endotoxemia; Escherichia coli; Heart; HEK293 Cells; Humans; Hypotension; Immunoblotting; In Vitro Techniques; Lipopolysaccharides; Mass Spectrometry; Metalloporphyrins; Mice; Mice, Inbred C57BL; Models, Animal; Nitric Oxide; Nitric Oxide Synthase; Oxidation-Reduction; Peroxynitrous Acid; Protein Processing, Post-Translational; Proteins; Rats; Rats, Wistar; S-Nitroso-N-Acetylpenicillamine; Sensitivity and Specificity; Sepsis; Signal Transduction; Telemetry; Tyrosine | 2011 |
Horseradish peroxidase compound I as a tool to investigate reactive protein-cysteine residues: from quantification to kinetics.
Topics: Animals; Chemistry, Analytic; Cloning, Molecular; Cysteine; Escherichia coli; Gammaproteobacteria; Gene Expression; Histidine; Horseradish Peroxidase; Hydrogen Peroxide; Hydrogen-Ion Concentration; Kinetics; Oligopeptides; Oxidation-Reduction; Oxygen; Peroxiredoxins; Peroxynitrous Acid; Rats; Recombinant Proteins; Saccharomyces cerevisiae; Spectrophotometry | 2011 |
L-cysteine attenuates peroxynitrite-elicited cytotoxicity to spiral ganglion neurons: possible relation to hearing loss.
Topics: Animals; Antioxidants; Cell Survival; Cells, Cultured; Cysteine; Hearing Loss; In Situ Nick-End Labeling; Microscopy, Confocal; Neurons; Oxidants; Peroxynitrous Acid; Rats; Spiral Ganglion | 2011 |
Hydroperoxide and peroxynitrite reductase activity of poplar thioredoxin-dependent glutathione peroxidase 5: kinetics, catalytic mechanism and oxidative inactivation.
Topics: Amino Acid Substitution; Catalytic Domain; Cysteine; Dimerization; Glutathione Peroxidase; Kinetics; Mutagenesis, Site-Directed; Oxidation-Reduction; Oxidoreductases; Peroxynitrous Acid; Plant Proteins; Populus; Protein Structure, Quaternary; Protein Structure, Secondary; Recombinant Proteins; Substrate Specificity; Sulfenic Acids; tert-Butylhydroperoxide | 2012 |
Nitric oxide, peroxynitrite, S-nitrosothiols and thiols are unlikely to exert their effects on recombinant cyclooxygenase-1 and cyclooxygenase-2 activity in vitro by modifying cysteine moieties.
Topics: Arachidonic Acid; Blood Platelets; Cyclooxygenase 1; Cyclooxygenase 2; Cysteine; Ethylmaleimide; Humans; Nitric Oxide; Peroxynitrous Acid; Recombinant Proteins; S-Nitrosothiols | 2012 |
Reactive nitrogen oxide species-induced post-translational modifications in human hemoglobin and the association with cigarette smoking.
Topics: Amino Acid Sequence; Chromatography, High Pressure Liquid; Cysteine; Hemoglobins; Humans; Methionine; Molecular Sequence Data; Oxidation-Reduction; Peptides; Peroxynitrous Acid; Protein Processing, Post-Translational; Reactive Nitrogen Species; Smoking; Spectrometry, Mass, Electrospray Ionization; Sulfinic Acids; Tyrosine | 2012 |
S-nitrosylation regulates mitochondrial quality control via activation of parkin.
Topics: Animals; Cysteine; Enzyme Activation; Humans; Membrane Potential, Mitochondrial; Mitochondria; Mitophagy; Nitric Oxide; Peroxynitrous Acid; Ubiquitin-Protein Ligases; Ubiquitination; Zebrafish | 2013 |
Mechanism of cysteine oxidation by peroxynitrite: An integrated experimental and theoretical study.
Topics: Cysteine; Fluorides; Kinetics; Molecular Conformation; Molecular Dynamics Simulation; Oxidation-Reduction; Peroxynitrous Acid; Polyethylenes; Quantum Theory; Resins, Synthetic | 2013 |
Structural and molecular basis of the peroxynitrite-mediated nitration and inactivation of Trypanosoma cruzi iron-superoxide dismutases (Fe-SODs) A and B: disparate susceptibilities due to the repair of Tyr35 radical by Cys83 in Fe-SODB through intramolec
Topics: Animals; Binding Sites; Blotting, Western; Catalytic Domain; Chagas Disease; Crystallography, X-Ray; Cysteine; Electron Spin Resonance Spectroscopy; Electron Transport; Enzyme Activation; Host-Parasite Interactions; Isoenzymes; Kinetics; Models, Molecular; Molecular Dynamics Simulation; Mutagenesis, Site-Directed; Nitrates; Peroxynitrous Acid; Protein Binding; Protein Structure, Secondary; Protozoan Proteins; Reactive Oxygen Species; Superoxide Dismutase; Trypanosoma cruzi; Tyrosine | 2014 |
Low serum ferroxidase I activity is associated with mortality in heart failure and related to both peroxynitrite-induced cysteine oxidation and tyrosine nitration of ceruloplasmin.
Topics: Aged; Aged, 80 and over; Biomarkers; C-Reactive Protein; Case-Control Studies; Ceruloplasmin; Cohort Studies; Cysteine; Female; Follow-Up Studies; Heart Failure; Humans; Male; Natriuretic Peptide, Brain; Norepinephrine; Oxidation-Reduction; Peroxynitrous Acid; Prognosis; Proportional Hazards Models; Survival Rate; Tyrosine | 2014 |
Copper futures: ceruloplasmin and heart failure.
Topics: Ceruloplasmin; Cysteine; Female; Heart Failure; Humans; Male; Peroxynitrous Acid; Tyrosine | 2014 |
Inactivation of the pore-forming toxin Sticholysin I by peroxynitrite: protection by cys groups incorporated in the toxin.
Topics: Adult; Cysteine; Erythrocytes; Hemolysis; Humans; Liposomes; Organic Chemicals; Oxidation-Reduction; Permeability; Peroxynitrous Acid; Spectrometry, Fluorescence; Sulfhydryl Compounds; Young Adult | 2014 |
Nitroxyl (HNO) reacts with molecular oxygen and forms peroxynitrite at physiological pH. Biological Implications.
Topics: Acetylcysteine; Algorithms; Animals; Boron Compounds; Boronic Acids; Captopril; Cattle; Chromatography, High Pressure Liquid; Coumarins; Cysteine; Dithiothreitol; Humans; Hydrogen Sulfide; Hydrogen-Ion Concentration; Kinetics; Mass Spectrometry; Models, Chemical; Nitrogen Oxides; Oxidation-Reduction; Oxygen; Peroxynitrous Acid; Serum Albumin; Spectrophotometry; Sulfhydryl Compounds | 2014 |
Interaction between hydrogen sulfide-induced sulfhydration and tyrosine nitration in the KATP channel complex.
Topics: Animals; Calcium Chloride; CHO Cells; Cricetulus; Cysteine; Dose-Response Relationship, Drug; Ileum; KATP Channels; Mice; Molsidomine; Muscle Contraction; Muscle, Smooth; Mutation; Peroxynitrous Acid; Protein Processing, Post-Translational; Signal Transduction; Sulfides; Sulfonylurea Receptors; Transfection; Tyrosine | 2015 |
Synthetic modeling chemistry of iron-sulfur clusters in nitric oxide signaling.
Topics: Animals; Anti-Inflammatory Agents; Cell Line; Crystallography, X-Ray; Cysteine; Cytokines; Hydrogen Sulfide; Iron; Iron-Sulfur Proteins; Macrophages; Mice; Molecular Conformation; Nitric Oxide; Nitrogen Oxides; Oxidation-Reduction; Oxygen; Peroxynitrous Acid; Signal Transduction; Spectrometry, Fluorescence | 2015 |
High oxygen modifies vasodilator effect of cysteine via enhanced oxidative stress and thromboxane production in the rat mesenteric artery.
Topics: 1,2-Dihydroxybenzene-3,5-Disulfonic Acid Disodium Salt; Alkynes; Animals; Cysteine; Glyburide; Glycine; Glycoproteins; Mesenteric Arteries; NADPH Oxidases; Oxidative Stress; Oxygen; Peroxynitrous Acid; Rats; Rats, Wistar; Superoxides; Thromboxanes; Vasodilation | 2016 |
Rapid peroxynitrite reduction by human peroxiredoxin 3: Implications for the fate of oxidants in mitochondria.
Topics: Carbon Dioxide; Cysteine; Humans; Hydrogen Peroxide; Kinetics; Mitochondria; Oxidants; Oxidation-Reduction; Peroxiredoxin III; Peroxiredoxins; Peroxynitrous Acid; Protein Processing, Post-Translational; Signal Transduction | 2019 |
Exploring Idiopathic Pulmonary Fibrosis Biomarker by Simultaneous Two-Photon Fluorescence Imaging of Cysteine and Peroxynitrite.
Topics: Animals; Biomarkers; Cysteine; Glutathione; Idiopathic Pulmonary Fibrosis; Mice; Optical Imaging; Peroxynitrous Acid | 2022 |