Page last updated: 2024-09-03

peroxynitrous acid and calpain

peroxynitrous acid has been researched along with calpain in 14 studies

Compound Research Comparison

Studies
(peroxynitrous acid)
Trials
(peroxynitrous acid)
Recent Studies (post-2010)
(peroxynitrous acid)
Studies
(calpain)
Trials
(calpain)
Recent Studies (post-2010) (calpain)
3,303211,2307,019252,422

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's11 (78.57)29.6817
2010's3 (21.43)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Barbera, A; Caputi, AP; Centorrino, T; Chatterjee, PK; Ciccolo, A; Cuzzocrea, S; Dugo, L; Fulia, F; Mazzon, E; McDonald, MC; Serraino, I; Thiemermann, C1
Befus, AD; Forsythe, P1
Armstrong, JS; Cheung, NS; Halliwell, B; Jones, DP; Rose, P; Schantz, JT; Siau, JL; Whiteman, M1
Aarts, M; Arundine, M; Lau, A; Tymianski, M1
Gambardella, L; Maccaglia, A; Malorni, W; Matarrese, P; Minetti, M; Pietraforte, D; Straface, E; Vona, R1
Giasson, BI; Hodara, R; Ischiropoulos, H; Lee, VM; Lynch, DR; Mishizen-Eberz, AJ; Norris, EH; Trojanowski, JQ1
Deng, Y; Hall, ED; Mbye, LH; Singh, IN; Sullivan, PG1
Hall, ED; Rabchevsky, AG; Xiong, Y1
Deng, Y; Gao, X; Hall, ED; Thompson, BM1
Carrico, KM; Deng-Bryant, Y; Hall, ED; Singh, IN1
Hall, ED; Xiong, Y1
Annamalai, B; Dhammu, TS; Dhindsa, TS; Khan, M; Matsuda, F; Singh, AK; Singh, I1
Agrawal, A; Ahmad, T; Bhatraju, NK; Bodas, M; Ghosh, B; Guleria, R; Pant, R; Pattnaik, B1
Dhammu, TS; Khan, M; Singh, AK; Singh, I1

Other Studies

14 other study(ies) available for peroxynitrous acid and calpain

ArticleYear
Effects of calpain inhibitor I on multiple organ failure induced by zymosan in the rat.
    Critical care medicine, 2002, Volume: 30, Issue:10

    Topics: Animals; Calpain; Cell Movement; Cyclooxygenase 2; Dose-Response Relationship, Drug; Glycoproteins; Immunohistochemistry; Intestinal Mucosa; Intestines; Isoenzymes; Liver; Lung; Male; Malondialdehyde; Multiple Organ Failure; Neutrophils; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Peritoneum; Peritonitis; Peroxidase; Peroxynitrous Acid; Poly Adenosine Diphosphate Ribose; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Sprague-Dawley; Tyrosine; Zymosan

2002
Inhibition of calpain is a component of nitric oxide-induced down-regulation of human mast cell adhesion.
    Journal of immunology (Baltimore, Md. : 1950), 2003, Jan-01, Volume: 170, Issue:1

    Topics: Calpain; Cell Adhesion; Cyclic GMP; Dipeptides; Down-Regulation; Enzyme Activation; Enzyme Inhibitors; Fibronectins; Humans; Leupeptins; Mast Cells; Nitric Oxide; Nitric Oxide Donors; Peroxynitrous Acid; Protein Binding; S-Nitroso-N-Acetylpenicillamine; S-Nitrosoglutathione; Tumor Cells, Cultured

2003
Peroxynitrite mediates calcium-dependent mitochondrial dysfunction and cell death via activation of calpains.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2004, Volume: 18, Issue:12

    Topics: Calcium; Calpain; Cell Death; Chondrocytes; Enzyme Activation; Humans; Membrane Potentials; Mitochondria; Peroxynitrous Acid

2004
Vulnerability of central neurons to secondary insults after in vitro mechanical stretch.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2004, Sep-15, Volume: 24, Issue:37

    Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Apoptosis; Brain Injuries; Calpain; Cell Nucleus; Cells, Cultured; Cysteine Endopeptidases; DNA; DNA Fragmentation; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; In Situ Nick-End Labeling; In Vitro Techniques; Intracellular Membranes; Membrane Potentials; Mice; Mitochondria; N-Methylaspartate; Neurons; Neurotoxins; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Oxidative Stress; Peroxynitrous Acid; Porphyrins; Reactive Oxygen Species; Receptors, N-Methyl-D-Aspartate; Recombinant Fusion Proteins; Stress, Mechanical; Superoxide Dismutase

2004
Peroxynitrite induces senescence and apoptosis of red blood cells through the activation of aspartyl and cysteinyl proteases.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2005, Volume: 19, Issue:3

    Topics: Anion Exchange Protein 1, Erythrocyte; Apoptosis; Aspartic Acid Endopeptidases; Calpain; Caspases; Cathepsin E; Cysteine Endopeptidases; Erythrocytes; Glutathione; Glycophorins; Humans; Methemoglobin; Microscopy, Electron, Scanning; Oxidation-Reduction; Oxidative Stress; Peroxynitrous Acid; Phosphatidylserines

2005
Cleavage of alpha-synuclein by calpain: potential role in degradation of fibrillized and nitrated species of alpha-synuclein.
    Biochemistry, 2005, May-31, Volume: 44, Issue:21

    Topics: alpha-Synuclein; Calpain; Chymotrypsin; Humans; Hydrolysis; Microscopy, Immunoelectron; Nerve Degeneration; Nerve Tissue Proteins; Nitrates; Parkinson Disease; Peptide Fragments; Peroxynitrous Acid; Recombinant Proteins; Solubility; Synucleins; Tyrosine

2005
Time course of post-traumatic mitochondrial oxidative damage and dysfunction in a mouse model of focal traumatic brain injury: implications for neuroprotective therapy.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2006, Volume: 26, Issue:11

    Topics: Animals; Blotting, Northern; Brain Hemorrhage, Traumatic; Calpain; Cytoskeleton; Male; Membrane Lipids; Membrane Proteins; Mice; Microscopy, Electron; Mitochondria; Nerve Degeneration; Neuroprotective Agents; Oxidative Stress; Oxygen Consumption; Peroxynitrous Acid; Reactive Oxygen Species; Tyrosine

2006
Role of peroxynitrite in secondary oxidative damage after spinal cord injury.
    Journal of neurochemistry, 2007, Volume: 100, Issue:3

    Topics: Aldehydes; Animals; Biomarkers; Calcium Signaling; Calpain; Disease Progression; Female; Free Radical Scavengers; Free Radicals; Lipid Peroxidation; Nerve Degeneration; Nitric Oxide; Oxidative Stress; Peptide Fragments; Peroxynitrous Acid; Rats; Rats, Sprague-Dawley; Spectrin; Spinal Cord Injuries; Time Factors; Tyrosine; Up-Regulation

2007
Temporal relationship of peroxynitrite-induced oxidative damage, calpain-mediated cytoskeletal degradation and neurodegeneration after traumatic brain injury.
    Experimental neurology, 2007, Volume: 205, Issue:1

    Topics: Aldehydes; Animals; Brain; Brain Injuries; Calcium; Calpain; Cerebral Cortex; Cytoskeleton; Lipid Peroxidation; Male; Mice; Mice, Inbred Strains; Nerve Degeneration; Nerve Tissue Proteins; Nitrates; Oxidative Stress; Peroxynitrous Acid; Spectrin; Time Factors; Tissue Distribution; Tyrosine

2007
Neuroprotective effects of tempol, a catalytic scavenger of peroxynitrite-derived free radicals, in a mouse traumatic brain injury model.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2008, Volume: 28, Issue:6

    Topics: Animals; Behavior, Animal; Brain Injuries; Calpain; Catalysis; Cyclic N-Oxides; Disease Models, Animal; Dose-Response Relationship, Drug; Free Radicals; Male; Mice; Mitochondria; Oxidative Stress; Peroxynitrous Acid; Spectrin; Spin Labels

2008
Pharmacological evidence for a role of peroxynitrite in the pathophysiology of spinal cord injury.
    Experimental neurology, 2009, Volume: 216, Issue:1

    Topics: Animals; Antioxidants; Calcium Signaling; Calpain; Cell Respiration; Cyclic N-Oxides; Disease Models, Animal; Drug Administration Schedule; Female; Free Radicals; Lipid Peroxidation; Mitochondria; Nerve Degeneration; Oxidative Stress; Peroxynitrous Acid; Rats; Rats, Sprague-Dawley; Spectrin; Spin Labels; Spinal Cord; Spinal Cord Injuries

2009
Targeting the nNOS/peroxynitrite/calpain system to confer neuroprotection and aid functional recovery in a mouse model of TBI.
    Brain research, 2016, Jan-01, Volume: 1630

    Topics: Animals; Brain; Brain Injuries; Calpain; Disease Models, Animal; Male; Mice, Inbred C57BL; Motor Activity; Neurons; Neuroprotective Agents; Nitric Oxide Synthase Type I; Peroxynitrous Acid; Phosphorylation; Random Allocation; Recovery of Function; S-Nitrosoglutathione

2016
IL-4 promotes asymmetric dimethylarginine accumulation, oxo-nitrative stress, and hypoxic response-induced mitochondrial loss in airway epithelial cells.
    The Journal of allergy and clinical immunology, 2016, Volume: 138, Issue:1

    Topics: Amidohydrolases; Apoptosis; Arginine; Asthma; Calpain; Cell Line; Cells, Cultured; Cytokines; Epithelial Cells; Humans; Hypoxia; Inflammation Mediators; Interleukin-4; Mitochondria; Nitric Oxide; Oxidative Stress; Peroxynitrous Acid; Proteolysis; Reactive Oxygen Species; Respiratory Mucosa

2016
Amelioration of spinal cord injury in rats by blocking peroxynitrite/calpain activity.
    BMC neuroscience, 2018, 08-13, Volume: 19, Issue:1

    Topics: Animals; Brain; Calpain; Disease Models, Animal; Male; Neurons; Neuroprotective Agents; Nitric Oxide Synthase Type I; Nitrosoguanidines; Peroxynitrous Acid; Rats, Sprague-Dawley; Recovery of Function; Spinal Cord Injuries

2018