Page last updated: 2024-09-03

peroxynitrous acid and ascorbic acid

peroxynitrous acid has been researched along with ascorbic acid in 51 studies

Compound Research Comparison

Studies
(peroxynitrous acid)
Trials
(peroxynitrous acid)
Recent Studies (post-2010)
(peroxynitrous acid)
Studies
(ascorbic acid)
Trials
(ascorbic acid)
Recent Studies (post-2010) (ascorbic acid)
3,303211,23045,2612,49711,176

Protein Interaction Comparison

ProteinTaxonomyperoxynitrous acid (IC50)ascorbic acid (IC50)
Chain A, Hyaluronidase, phage associatedStreptococcus pyogenes1000
UreaseCanavalia ensiformis (jack bean)8.59
Solute carrier family 23 member 1Homo sapiens (human)156

Research

Studies (51)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (5.88)18.2507
2000's30 (58.82)29.6817
2010's16 (31.37)24.3611
2020's2 (3.92)2.80

Authors

AuthorsStudies
Hiramoto, K; Kikugawa, K; Tomiyama, S1
Hiramoto, K; Kikugawa, K; Nakauchi, K; Tomiyama, S1
Fink, MP; Hodin, RA; Unno, N1
Haramaki, N; Ikeda, H; Imaizumi, T; Murohara, T; Takajo, Y1
Angeles, FM; Bobrowski, P; Miller, MJ; Reuter, BK; Sandoval, M1
Furue, M; Goto, Y; Hayashi, H; Kogawa, N; Takahashi, O; Tsuchiya, M; Uchi, H; Watanabe, N1
Chang, WC; Chen, HY; Gau, RJ; Hseu, YC; Liu, TZ; Lu, FJ; Wang, SY; Yang, HL1
Keilhoff, G; Noack, H; Possel, H; Wolf, G1
Cadenas, E; Laranjinha, J1
Halliwell, B; Ketsawatsakul, U; Whiteman, M1
Gutiérrez-Martín, Y; Gutiérrez-Merino, C; Henao, F; Martín-Romero, FJ1
Beckman, JS; Parks, DA; Teng, RJ; Ye, YZ1
Brimer, CM; Hooper, DC; Kean, RB; Koprowski, H; Mikheeva, T; Scott, GS; Spitsin, SV; Zborek, A1
Betancor-Fernandez, A; Polidori, MC; Sies, H; Stahl, W1
Gorren, AC; Mayer, B; Pfeiffer, S; Schmidt, K; Schrammel, A1
Dikalov, S; Harrison, DG; Kuzkaya, N; Weissmann, N2
Barone, MC; Brookes, PS; Darley-Usmar, VM1
Devaraj, S; Jialal, I; Venugopal, SK1
Fukushi, Y; Ichiba, T; Sakihama, Y; Shimoji, H; Tahara, S; Tamaki, R; Yamasaki, H1
Choi, JS; Chung, HY; Jung, HA; Jung, MJ; Kim, JY1
Cantoni, O; Fiorani, M; Guidarelli, A1
Kissner, R; Koppenol, WH; Kurz, CR; Nauser, T; Perrin, D1
Batthyány, C; Botti, H; Freeman, BA; Radi, R; Rubbo, H; Trostchansky, A1
DeMaster, EG; Lai, JC; Quach, HT; Smith, WE; Vatassery, GT1
Dikshit, M; Raghavan, SA; Saini, R; Sharma, P1
Buettner, GR; Clark, CB; Davies, LR; Kerber, RE; Kregel, KC; Martin, SM; Miller, FJ; Xu, L; Zhang, Y1
Halliwell, B; Jenner, A; Peng, ZF; Tang, SY; Whiteman, M; Yong, EL1
Arai, H; Nakamura, K1
Chichuk, TV; Klebanov, GI; Osipov, AN; Poltanov, EA; Vladimirov, YA1
Abraham, DJ; Black, CM; Bruckdorfer, KR; Dooley, A; Gao, B; Jacobs, M; Shi-Wen, X1
Fearon, IM; Gautier, M; Zhang, H1
Calcerrada, P; Peluffo, G; Piacenza, L; Pizzano, N; Radi, R1
Alleyne, CH; Dhandapani, KM; Laird, MD; Singh, N; Sukumari-Ramesh, S; Vender, JR1
Batinic-Haberle, I; Benov, L; Rajic, Z1
Gunasekara, DB; Hulvey, MK; Lunte, SM1
Halim, AS; Kishore, RK; Sirajudeen, KN; Syazana, MS1
Asayama, S; Kawakami, H; Nakajima, T1
Lu, C; Teng, X; Wang, Z1
Azzolini, C; Cantoni, O; Cerioni, L; Fiorani, M; Guidarelli, A1
Koebke, KJ; Lerner, L; Liu, X; Pacheco, AA; Pauly, DJ1
Avidan-Shlomovich, S; Gross, Z1
Belhomme, M; Buzzacott, P; Guerrero, F; Lambrechts, K; Mazur, A; Theron, M; Wang, Q1
Ghahramani, M; Khoshaman, K; Kurganov, BI; Moghadam, SS; Yousefi, R1
Chen, AY; Chen, C; Lü, JM; Yao, Q1
Chisté, RC; Fernandes, E; Lima, JL; Ribeiro, AB1
Alavianehr, MM; Kurganov, BI; Moghadam, SS; Moosavi-Movahedi, AA; Oryan, A; Tamaddon, AM; Yousefi, R1
Cantoni, O; Fiorani, M; Guidarelli, A; Scotti, M1
Castanheira, JRPT; Castanho, REP; Chagas, EFB; Duarte, MIS; Martins, LPA; Pagliari, C; Rocha, H; Therezo, ALS1
Abubshait, SA; Betiha, MA; Kana, MTHA; Negm, NA1
Constantinescu-Aruxandei, D; Doni, M; Hosu, IS; Oancea, F1

Reviews

2 review(s) available for peroxynitrous acid and ascorbic acid

ArticleYear
A combination of two antioxidants (an SOD mimic and ascorbate) produces a pro-oxidative effect forcing Escherichia coli to adapt via induction of oxyR regulon.
    Anti-cancer agents in medicinal chemistry, 2011, May-01, Volume: 11, Issue:4

    Topics: Adaptation, Physiological; Animals; Antioxidants; Ascorbic Acid; Biomimetic Materials; Escherichia coli; Escherichia coli Proteins; Gene Expression Regulation, Bacterial; Humans; Hydrogen Peroxide; Peroxynitrous Acid; Repressor Proteins; Superoxide Dismutase; Superoxides

2011
Effectuality of chitosan biopolymer and its derivatives during antioxidant applications.
    International journal of biological macromolecules, 2020, Dec-01, Volume: 164

    Topics: Animals; Antioxidants; Ascorbic Acid; Biopolymers; Biphenyl Compounds; Chelating Agents; Chitosan; Citric Acid; Free Radical Scavengers; Gallic Acid; Hydroxyl Radical; Metals; Peroxynitrous Acid; Phenols; Picrates; Polyphenols; Spectroscopy, Fourier Transform Infrared

2020

Trials

1 trial(s) available for peroxynitrous acid and ascorbic acid

ArticleYear
Superoxide-mediated inactivation of nitric oxide and peroxynitrite formation by tobacco smoke in vascular endothelium: studies in cultured cells and smokers.
    American journal of physiology. Heart and circulatory physiology, 2009, Volume: 296, Issue:6

    Topics: Adult; alpha-Tocopherol; Animals; Antioxidants; Aorta; Ascorbic Acid; Brachial Artery; Cattle; Cells, Cultured; Endothelial Cells; Female; Humans; Male; Nitric Oxide; Nitric Oxide Synthase Type III; Oxidative Stress; Peroxynitrous Acid; Smoking; Superoxides; Young Adult

2009

Other Studies

48 other study(ies) available for peroxynitrous acid and ascorbic acid

ArticleYear
Effective inhibition by beta-carotene of cellular DNA breaking induced by peroxynitrous acid.
    Free radical research, 1999, Volume: 30, Issue:1

    Topics: Antioxidants; Ascorbic Acid; beta Carotene; Chromans; Dimethyl Sulfoxide; DNA; DNA Damage; Dose-Response Relationship, Drug; Electrophoresis, Agar Gel; Free Radical Scavengers; Furans; HL-60 Cells; Humans; Mannitol; Microscopy, Fluorescence; Molsidomine; Nitrous Acid; Peroxynitrous Acid; Solubility; Sorbic Acid; Time Factors

1999
Effect of beta-carotene on the transformation of tyrosine by nitrogen dioxide and peroxynitrous acid.
    Free radical research, 1999, Volume: 30, Issue:1

    Topics: Ascorbic Acid; beta Carotene; Dioxanes; Dose-Response Relationship, Drug; Free Radical Scavengers; Nitrogen Dioxide; Nitrous Acid; Peroxynitrous Acid; Time Factors; Tyrosine; Vitamin E

1999
Acidic conditions exacerbate interferon-gamma-induced intestinal epithelial hyperpermeability: role of peroxynitrous acid.
    Critical care medicine, 1999, Volume: 27, Issue:8

    Topics: Adenosine Triphosphate; Ascorbic Acid; Caco-2 Cells; Cell Membrane Permeability; Cyclic N-Oxides; Dimethyl Sulfoxide; Drug Evaluation, Preclinical; Electric Impedance; Free Radical Scavengers; Humans; Hydrogen-Ion Concentration; Imidazoles; Interferon-gamma; Intestinal Mucosa; Nitric Oxide; Nitric Oxide Synthase; Nitrous Acid; omega-N-Methylarginine; Peroxynitrous Acid; Time Factors

1999
Augmented oxidative stress of platelets in chronic smokers. Mechanisms of impaired platelet-derived nitric oxide bioactivity and augmented platelet aggregability.
    Journal of the American College of Cardiology, 2001, Nov-01, Volume: 38, Issue:5

    Topics: Administration, Oral; Adult; Antioxidants; Ascorbic Acid; Biological Availability; Blood Platelets; Case-Control Studies; Chronic Disease; Cyclic GMP; Free Radical Scavengers; Glutathione; Humans; Male; Nitric Oxide; Oxidation-Reduction; Oxidative Stress; Peroxynitrous Acid; Platelet Aggregation; Smoking; Time Factors; Tyrosine

2001
Dietary antioxidants protect gut epithelial cells from oxidant-induced apoptosis.
    BMC complementary and alternative medicine, 2001, Volume: 1

    Topics: Animals; Antioxidants; Apoptosis; Ascorbic Acid; Cat's Claw; Cells, Cultured; Humans; Hydrogen Peroxide; Intestinal Mucosa; Mice; Necrosis; Oxidants; Peroxynitrous Acid; Tea

2001
CX-659S: a novel diaminouracil derivative that has antioxidative and acute anti-inflammatory activities.
    European journal of pharmacology, 2002, Mar-08, Volume: 438, Issue:3

    Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Arachidonic Acid; Ascorbic Acid; Chromans; Dose-Response Relationship, Drug; Ear; Edema; Lipid Peroxidation; Male; Mice; Mice, Inbred ICR; Oxidation-Reduction; Peroxynitrous Acid; Rats; Rats, Sprague-Dawley; Tetradecanoylphorbol Acetate; Uracil

2002
Humic acid induces the generation of nitric oxide in human umbilical vein endothelial cells: stimulation of nitric oxide synthase during cell injury.
    Free radical biology & medicine, 2002, Apr-01, Volume: 32, Issue:7

    Topics: Antioxidants; Ascorbic Acid; Blotting, Western; Calcium; Carrier Proteins; Cell Death; Cells, Cultured; Chelating Agents; Dexamethasone; DNA; DNA Fragmentation; Dose-Response Relationship, Drug; Egtazic Acid; Endothelium, Vascular; Enzyme Inhibitors; Humans; Humic Substances; L-Lactate Dehydrogenase; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; Peroxynitrous Acid; Protein Kinase C; Superoxide Dismutase; Ubiquitin-Protein Ligases; Vitamin E

2002
Life imaging of peroxynitrite in rat microglial and astroglial cells: Role of superoxide and antioxidants.
    Glia, 2002, Volume: 38, Issue:4

    Topics: Animals; Animals, Newborn; Antioxidants; Ascorbic Acid; Astrocytes; Cells, Cultured; Encephalitis; Enzyme Inhibitors; Fluorescent Antibody Technique; Fluorescent Dyes; Glutathione; Interferon-gamma; Lipopolysaccharides; Microglia; NADPH Oxidases; Neurodegenerative Diseases; Nitric Oxide; Nitric Oxide Synthase; Oxidative Stress; Peroxynitrous Acid; Rats; Rats, Wistar; Superoxides; Tetradecanoylphorbol Acetate

2002
Oxidation of DOPAC by nitric oxide: effect of superoxide dismutase.
    Journal of neurochemistry, 2002, Volume: 81, Issue:4

    Topics: 3,4-Dihydroxyphenylacetic Acid; Ascorbic Acid; Benzoquinones; Electron Spin Resonance Spectroscopy; Glutathione; Models, Biological; Nitric Oxide; Oxidation-Reduction; Peroxynitrous Acid; Superoxide Dismutase

2002
A reassessment of the peroxynitrite scavenging activity of uric acid.
    Annals of the New York Academy of Sciences, 2002, Volume: 962

    Topics: alpha 1-Antitrypsin; Antioxidants; Ascorbic Acid; Benzothiazoles; Bicarbonates; Chromans; Coloring Agents; Glutathione; Guanine; Humans; Indicators and Reagents; Peroxynitrous Acid; Pyrogallol; Reactive Nitrogen Species; Serine Proteinase Inhibitors; Sulfonic Acids; Tyrosine; Uric Acid

2002
The NADH oxidase activity of the plasma membrane of synaptosomes is a major source of superoxide anion and is inhibited by peroxynitrite.
    Journal of neurochemistry, 2002, Volume: 82, Issue:3

    Topics: Animals; Ascorbate Oxidase; Ascorbic Acid; Brain Chemistry; Cell Membrane; Coenzymes; Cytochrome c Group; Enzyme Activation; Multienzyme Complexes; NADH, NADPH Oxidoreductases; Peroxynitrous Acid; Rats; Rats, Wistar; Superoxides; Synaptosomes; Ubiquinone

2002
Urate produced during hypoxia protects heart proteins from peroxynitrite-mediated protein nitration.
    Free radical biology & medicine, 2002, Nov-01, Volume: 33, Issue:9

    Topics: Animals; Ascorbic Acid; Brain; Heart; Hypoxanthine; Hypoxia; In Vitro Techniques; Myocardium; Nitric Oxide; Nitrosation; Peroxynitrous Acid; Rats; Rats, Sprague-Dawley; Tyrosine; Urate Oxidase; Uric Acid; Xanthine Dehydrogenase; Xanthine Oxidase

2002
Comparison of uric acid and ascorbic acid in protection against EAE.
    Free radical biology & medicine, 2002, Nov-15, Volume: 33, Issue:10

    Topics: Albumins; Animals; Antioxidants; Ascorbic Acid; Blood-Brain Barrier; Cell Line; Encephalomyelitis, Autoimmune, Experimental; Free Radicals; Immunohistochemistry; Iron; Lipid Peroxidation; Mice; Molsidomine; Myelin Sheath; Nitric Oxide; Oxygen; Peroxynitrous Acid; Rhodamines; Time Factors; Tyrosine; Uric Acid

2002
In vitro antioxidant activity of 2,5,7,8-tetramethyl-2-(2'-carboxyethyl)-6-hydroxychroman (alpha-CEHC), a vitamin E metabolite.
    Free radical research, 2002, Volume: 36, Issue:8

    Topics: Antioxidants; Ascorbic Acid; Chromans; Dose-Response Relationship, Drug; Humans; In Vitro Techniques; Models, Chemical; Nitrogen; Oxygen; Peroxynitrous Acid; Propionates; Spectrometry, Fluorescence; Time Factors; Tyrosine; Vitamin E

2002
S-nitrosation of glutathione by nitric oxide, peroxynitrite, and (*)NO/O(2)(*-).
    Free radical biology & medicine, 2003, Apr-15, Volume: 34, Issue:8

    Topics: Albumins; Ascorbic Acid; Cyclic N-Oxides; Dose-Response Relationship, Drug; Electron Spin Resonance Spectroscopy; Free Radicals; Glutathione; Hydrogen-Ion Concentration; Macrophages; Models, Chemical; Nitric Oxide; Nitric Oxide Donors; Nitrosation; Oxygen; Peroxynitrous Acid; Reactive Oxygen Species; Rhodamines; S-Nitrosoglutathione; Spin Labels; Time Factors

2003
Interactions of peroxynitrite, tetrahydrobiopterin, ascorbic acid, and thiols: implications for uncoupling endothelial nitric-oxide synthase.
    The Journal of biological chemistry, 2003, Jun-20, Volume: 278, Issue:25

    Topics: Animals; Aorta; Ascorbic Acid; Biopterins; Cattle; Cells, Cultured; Endothelium, Vascular; Kinetics; Nitric Oxide Donors; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Peroxynitrous Acid; Spin Labels; Sulfhydryl Compounds

2003
Reversible inhibition of cytochrome c oxidase by peroxynitrite proceeds through ascorbate-dependent generation of nitric oxide.
    The Journal of biological chemistry, 2003, Jul-25, Volume: 278, Issue:30

    Topics: Animals; Apoptosis; Ascorbic Acid; Cattle; Chelating Agents; Dose-Response Relationship, Drug; Electron Transport Complex IV; Hydrogen-Ion Concentration; Mitochondria, Liver; Models, Chemical; Nitric Oxide; Oxidation-Reduction; Peroxynitrous Acid; Rats; Reactive Nitrogen Species; Superoxide Dismutase

2003
C-reactive protein decreases prostacyclin release from human aortic endothelial cells.
    Circulation, 2003, Oct-07, Volume: 108, Issue:14

    Topics: Aorta; Ascorbic Acid; C-Reactive Protein; Cells, Cultured; Coronary Vessels; Cytochrome P-450 Enzyme System; Endothelium, Vascular; Epoprostenol; Free Radical Scavengers; Humans; Intramolecular Oxidoreductases; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Peroxynitrous Acid; Prostaglandins F; Tyrosine; Uric Acid

2003
Enzymatic nitration of phytophenolics: evidence for peroxynitrite-independent nitration of plant secondary metabolites.
    FEBS letters, 2003, Oct-23, Volume: 553, Issue:3

    Topics: Antioxidants; Ascorbic Acid; Coumaric Acids; Enzyme Inhibitors; Free Radicals; Horseradish Peroxidase; Nitrates; Nitrites; Nitrogen Dioxide; Peroxidase; Peroxynitrous Acid; Phenols; Plants; Potassium Cyanide; Spectrophotometry

2003
Inhibitory activity of flavonoids from Prunus davidiana and other flavonoids on total ROS and hydroxyl radical generation.
    Archives of pharmacal research, 2003, Volume: 26, Issue:10

    Topics: 1-Butanol; Acetates; Animals; Antioxidants; Ascorbic Acid; Biphenyl Compounds; Catechin; Chromans; Drug Evaluation, Preclinical; Flavonoids; Free Radical Scavengers; Hesperidin; Hydrazines; Hydroxyl Radical; Kaempferols; Kidney; Male; Methanol; Methylene Chloride; Penicillamine; Peroxynitrous Acid; Picrates; Plant Extracts; Plant Stems; Prunus; Rats; Rats, Wistar; Reactive Oxygen Species; Structure-Activity Relationship; Water

2003
Enhancing effects of intracellular ascorbic acid on peroxynitrite-induced U937 cell death are mediated by mitochondrial events resulting in enhanced sensitivity to peroxynitrite-dependent inhibition of complex III and formation of hydrogen peroxide.
    The Biochemical journal, 2004, Mar-15, Volume: 378, Issue:Pt 3

    Topics: Ascorbic Acid; Cell Death; Dehydroascorbic Acid; Drug Synergism; Electron Transport Complex III; Humans; Hydrogen Peroxide; Ion Channels; Mitochondria; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Oxygen Consumption; Peroxynitrous Acid; U937 Cells

2004
Rapid scavenging of peroxynitrous acid by monohydroascorbate.
    Free radical biology & medicine, 2003, Dec-15, Volume: 35, Issue:12

    Topics: Ascorbic Acid; Electron Spin Resonance Spectroscopy; Hydrogen-Ion Concentration; Kinetics; Peroxynitrous Acid

2003
Peroxynitrite-mediated alpha-tocopherol oxidation in low-density lipoprotein: a mechanistic approach.
    Free radical biology & medicine, 2004, Jan-15, Volume: 36, Issue:2

    Topics: alpha-Tocopherol; Ascorbic Acid; Carbon Dioxide; gamma-Tocopherol; Humans; Kinetics; Lipid Peroxidation; Lipoproteins, LDL; Nitric Oxide; Oxidation-Reduction; Peroxynitrous Acid

2004
Oxidation of vitamin E and vitamin C and inhibition of brain mitochondrial oxidative phosphorylation by peroxynitrite.
    Journal of neuroscience research, 2004, Mar-15, Volume: 75, Issue:6

    Topics: Animals; Ascorbic Acid; Brain; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Cell Respiration; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Ionophores; Male; Mitochondria; Oxidation-Reduction; Oxidative Phosphorylation; Peroxynitrous Acid; Phosphorylation; Rats; Rats, Inbred F344; Vitamin E

2004
Ascorbate-mediated enhancement of reactive oxygen species generation from polymorphonuclear leukocytes: modulatory effect of nitric oxide.
    Journal of leukocyte biology, 2004, Volume: 75, Issue:6

    Topics: Animals; Apoptosis; Arachidonic Acid; Ascorbic Acid; Cells, Cultured; Dehydroascorbic Acid; Escherichia coli; Free Radical Scavengers; Humans; Macaca mulatta; Male; NADPH Oxidases; Neutrophils; Nitric Oxide; Nitric Oxide Synthase; Oxidation-Reduction; Oxygen; Peroxynitrous Acid; Phagocytosis; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species

2004
The nitric oxide synthase inhibitor N(G)-nitro-L-arginine decreases defibrillation-induced free radical generation.
    Resuscitation, 2004, Volume: 60, Issue:3

    Topics: Animals; Ascorbic Acid; Dogs; Electric Countershock; Electron Spin Resonance Spectroscopy; Enzyme Inhibitors; Free Radicals; Histocytochemistry; Myocardium; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Peroxynitrous Acid; Superoxides; Tyrosine

2004
Characterization of antioxidant and antiglycation properties and isolation of active ingredients from traditional chinese medicines.
    Free radical biology & medicine, 2004, Jun-15, Volume: 36, Issue:12

    Topics: Antioxidants; Ascorbic Acid; Benzothiazoles; Chromatography, High Pressure Liquid; Clusiaceae; DNA Damage; Dose-Response Relationship, Drug; Hypochlorous Acid; Lipid Peroxidation; Lipids; Mass Spectrometry; Medicine, Chinese Traditional; Models, Chemical; Nitrogen; Peroxynitrous Acid; Phenol; Phospholipids; Sulfonic Acids; Superoxides; Tyrosine; Xanthine Oxidase; Xanthones

2004
Effect of L-ascorbic acid on the oxidative modification of apolipoprotein E in human very-low-density lipoprotein.
    Journal of nutritional science and vitaminology, 2004, Volume: 50, Issue:1

    Topics: Amidines; Antioxidants; Apolipoproteins E; Ascorbic Acid; Heparin; Humans; Lipid Peroxidation; Lipoproteins, VLDL; Molsidomine; Oxidants; Peroxides; Peroxynitrous Acid

2004
Interactions of peroxynitrite with uric acid in the presence of ascorbate and thiols: implications for uncoupling endothelial nitric oxide synthase.
    Biochemical pharmacology, 2005, Aug-01, Volume: 70, Issue:3

    Topics: Animals; Ascorbic Acid; Cattle; Cells, Cultured; Drug Interactions; Endothelium, Vascular; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Peroxynitrous Acid; Sulfhydryl Compounds; Uncoupling Agents; Uric Acid

2005
Changes in superoxide dismutase activity and peroxynitrite content in rat peritoneal macrophages exposed to He-Ne laser radiation.
    Biochemistry. Biokhimiia, 2005, Volume: 70, Issue:12

    Topics: Animals; Ascorbic Acid; Fluoresceins; Lasers; Macrophages, Peritoneal; Male; Peroxynitrous Acid; Rats; Reactive Oxygen Species; Sodium Azide; Superoxide Dismutase

2005
Effect of nitric oxide and peroxynitrite on type I collagen synthesis in normal and scleroderma dermal fibroblasts.
    Free radical biology & medicine, 2007, Jul-15, Volume: 43, Issue:2

    Topics: Ascorbic Acid; Cell Survival; Collagen Type I; Fibroblasts; Humans; Kinetics; Nitric Oxide; Nitroprusside; Peroxynitrous Acid; Potassium Cyanide; Scleroderma, Systemic; Skin

2007
Peroxynitrite formation mediates LPC-induced augmentation of cardiac late sodium currents.
    Journal of molecular and cellular cardiology, 2008, Volume: 44, Issue:2

    Topics: Animals; Ascorbic Acid; Cell Line; Humans; Ion Channel Gating; Lysophosphatidylcholines; Male; Myocardium; NADPH Oxidases; Nitric Oxide; Peroxynitrous Acid; Rats; Rats, Wistar; Reactive Oxygen Species; Recombinant Proteins; Sodium Channels

2008
Astrocyte-derived glutathione attenuates hemin-induced apoptosis in cerebral microvascular cells.
    Glia, 2010, Nov-15, Volume: 58, Issue:15

    Topics: Acetylcysteine; Amino Acid Chloromethyl Ketones; Animals; Antioxidants; Apoptosis; Ascorbic Acid; Astrocytes; Brain; Caspase 3; Cells, Cultured; Curcumin; Dose-Response Relationship, Drug; Enzyme Inhibitors; Glutathione; Hemin; Humans; L-Lactate Dehydrogenase; Mice; Microvessels; Neuroprotective Agents; Nitric Oxide Synthase Type II; Peroxynitrous Acid; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerases; Time Factors

2010
In-channel amperometric detection for microchip electrophoresis using a wireless isolated potentiostat.
    Electrophoresis, 2011, Volume: 32, Issue:8

    Topics: Anions; Ascorbic Acid; Electrophoresis, Microchip; Glutathione; Peroxynitrous Acid; Trimethyl Ammonium Compounds; Tyrosine

2011
Tualang honey has higher phenolic content and greater radical scavenging activity compared with other honey sources.
    Nutrition research (New York, N.Y.), 2011, Volume: 31, Issue:4

    Topics: Antioxidants; Ascorbic Acid; Flavonoids; Free Radical Scavengers; Gallic Acid; Honey; Oxidative Stress; Peroxynitrous Acid; Phenols; Superoxides

2011
New water-soluble Mn-porphyrin with catalytic activity for superoxide dismutation and peroxynitrite decomposition.
    Metallomics : integrated biometal science, 2011, Volume: 3, Issue:7

    Topics: Animals; Antioxidants; Ascorbic Acid; Catalysis; Cell Survival; Hydrogen Peroxide; Lipopolysaccharides; Macrophages; Manganese; Metalloporphyrins; Mice; Peroxynitrous Acid; Solubility; Superoxides; Time Factors; Water

2011
Carbonate interlayered hydrotalcites-enhanced peroxynitrous acid chemiluminescence for high selectivity sensing of ascorbic acid.
    The Analyst, 2012, Apr-21, Volume: 137, Issue:8

    Topics: Aluminum Hydroxide; Ascorbic Acid; Beverages; Carbonates; Hot Temperature; Luminescence; Magnesium Hydroxide; Peroxynitrous Acid; Powder Diffraction; Static Electricity

2012
Superoxide dictates the mode of U937 cell ascorbic acid uptake and prevents the enhancing effects of the vitamin to otherwise nontoxic levels of reactive oxygen/nitrogen species.
    The Journal of nutritional biochemistry, 2013, Volume: 24, Issue:2

    Topics: Ascorbate Oxidase; Ascorbic Acid; bcl-2-Associated X Protein; Cell Line; Dehydroascorbic Acid; Humans; Hydrogen Peroxide; Membrane Potential, Mitochondrial; Peroxynitrous Acid; Reactive Oxygen Species; Superoxides; tert-Butylhydroperoxide; Xanthine Oxidase

2013
Does the oxidation of nitric oxide by oxyMyoglobin share an intermediate with the metMyoglobin-catalyzed isomerization of peroxynitrite?
    Inorganic chemistry, 2013, Jul-01, Volume: 52, Issue:13

    Topics: Animals; Ascorbic Acid; Catalysis; Horses; Isomerism; Metmyoglobin; Myoglobin; Nitric Oxide; Oxidation-Reduction; Peroxynitrous Acid

2013
Reaction mechanism for the highly efficient catalytic decomposition of peroxynitrite by the amphipolar iron(III) corrole 1-Fe.
    Dalton transactions (Cambridge, England : 2003), 2015, Jul-21, Volume: 44, Issue:27

    Topics: Ascorbic Acid; Catalysis; Fluorescein; Hydrogen Peroxide; Iron; Kinetics; Metalloporphyrins; Peroxynitrous Acid

2015
Antioxidants, endothelial dysfunction, and DCS: in vitro and in vivo study.
    Journal of applied physiology (Bethesda, Md. : 1985), 2015, Dec-15, Volume: 119, Issue:12

    Topics: Acetylcysteine; Angiotensin II; Animals; Antioxidants; Ascorbic Acid; Cell Death; Cell Survival; Cells, Cultured; Decompression Sickness; Diving; Endothelium, Vascular; Glutathione; Male; Nitric Oxide; Oxidative Stress; Peptidyl-Dipeptidase A; Peroxynitrous Acid; Rats; Rats, Sprague-Dawley; Superoxides; Thiobarbituric Acid Reactive Substances

2015
Evaluation of structure, chaperone-like activity and protective ability of peroxynitrite modified human α-Crystallin subunits against copper-mediated ascorbic acid oxidation.
    International journal of biological macromolecules, 2016, Volume: 87

    Topics: alpha-Crystallin A Chain; alpha-Crystallin B Chain; Animals; Ascorbic Acid; Cattle; Copper; Humans; Models, Molecular; Nucleic Acid Conformation; Peroxynitrous Acid

2016
Entacapone is an Antioxidant More Potent than Vitamin C and Vitamin E for Scavenging of Hypochlorous Acid and Peroxynitrite, and the Inhibition of Oxidative Stress-Induced Cell Death.
    Medical science monitor : international medical journal of experimental and clinical research, 2016, Mar-01, Volume: 22

    Topics: Antioxidants; Ascorbic Acid; Catechols; Cell Death; Free Radical Scavengers; Human Umbilical Vein Endothelial Cells; Humans; Hydrogen Peroxide; Hypochlorous Acid; Iron Chelating Agents; Nitriles; Oxidative Stress; Peroxynitrous Acid; Reactive Oxygen Species; Vitamin E

2016
Solanum diploconos fruits: profile of bioactive compounds and in vitro antioxidant capacity of different parts of the fruit.
    Food & function, 2016, May-18, Volume: 7, Issue:5

    Topics: Antioxidants; Ascorbic Acid; Brazil; Caffeic Acids; Carotenoids; Chromatography, High Pressure Liquid; Coumaric Acids; Free Radical Scavengers; Fruit; Hydrogen Peroxide; Hypochlorous Acid; Lutein; Nitric Oxide; Peroxynitrous Acid; Phenols; Plant Extracts; Reactive Nitrogen Species; Reactive Oxygen Species; Singlet Oxygen; Solanum; Superoxides; Tocopherols

2016
The structural damages of lens crystallins induced by peroxynitrite and methylglyoxal, two causative players in diabetic complications and preventive role of lens antioxidant components.
    International journal of biological macromolecules, 2017, Volume: 103

    Topics: Animals; Antioxidants; Ascorbic Acid; Cattle; Crystallins; Cytoprotection; Diabetes Complications; Glutathione; Lens, Crystalline; Peroxynitrous Acid; Protein Aggregates; Protein Multimerization; Protein Structure, Quaternary; Pyruvaldehyde

2017
Differentiation of Promonocytic U937 Cells to Monocytes Is Associated with Reduced Mitochondrial Transport of Ascorbic Acid.
    Oxidative medicine and cellular longevity, 2018, Volume: 2018

    Topics: Ascorbic Acid; Biological Transport; Cell Differentiation; Dimethyl Sulfoxide; Humans; Mitochondria; Monocytes; Peroxynitrous Acid; Sodium-Coupled Vitamin C Transporters; U937 Cells

2018
Paradoxical effects of vitamin C in Chagas disease.
    Parasitology international, 2018, Volume: 67, Issue:5

    Topics: Acute Disease; Animals; Antioxidants; Ascorbic Acid; Bilirubin; Chagas Disease; Chronic Disease; Disease Models, Animal; Inflammation; Iron; Male; Mice; Nitric Oxide; Oxidative Stress; Parasitemia; Peroxynitrous Acid; Trypanosoma cruzi

2018
The Scavenging Effect of Myoglobin from Meat Extracts toward Peroxynitrite Studied with a Flow Injection System Based on Electrochemical Reduction over a Screen-Printed Carbon Electrode Modified with Cobalt Phthalocyanine: Quantification and Kinetics.
    Biosensors, 2021, Jul-02, Volume: 11, Issue:7

    Topics: Ascorbic Acid; Biosensing Techniques; Carbon; Electrochemical Techniques; Electrochemistry; Electrodes; Flow Injection Analysis; Hydrogen Peroxide; Indoles; Kinetics; Limit of Detection; Meat; Myoglobin; Organometallic Compounds; Peroxynitrous Acid; Plant Extracts

2021