peroxynitrous acid has been researched along with arachidonic acid in 30 studies
| Studies (peroxynitrous acid) | Trials (peroxynitrous acid) | Recent Studies (post-2010) (peroxynitrous acid) | Studies (arachidonic acid) | Trials (arachidonic acid) | Recent Studies (post-2010) (arachidonic acid) |
|---|---|---|---|---|---|
| 3,303 | 21 | 1,230 | 19,295 | 486 | 3,040 |
| Protein | Taxonomy | peroxynitrous acid (IC50) | arachidonic acid (IC50) |
|---|---|---|---|
| 60 kDa heat shock protein, mitochondrial | Homo sapiens (human) | 4.5 | |
| Fatty acid-binding protein, adipocyte | Homo sapiens (human) | 2.75 | |
| 10 kDa heat shock protein, mitochondrial | Homo sapiens (human) | 4.5 | |
| 60 kDa chaperonin | Escherichia coli | 7.3 | |
| 10 kDa chaperonin | Escherichia coli | 7.3 | |
| Solute carrier organic anion transporter family member 1B3 | Homo sapiens (human) | 1.0715 | |
| Solute carrier organic anion transporter family member 1B1 | Homo sapiens (human) | 0.6026 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 24 (80.00) | 29.6817 |
| 2010's | 5 (16.67) | 24.3611 |
| 2020's | 1 (3.33) | 2.80 |
| Authors | Studies |
|---|---|
| García-Estañ, J; Lee, SS; Ortiz, MC | 1 |
| Furue, M; Goto, Y; Hayashi, H; Kogawa, N; Takahashi, O; Tsuchiya, M; Uchi, H; Watanabe, N | 1 |
| Cantoni, O; Guidarelli, A | 1 |
| Cantoni, O; Guidarelli, A; Sestili, P; Tommasini, I | 2 |
| Deeb, RS; Gamss, C; Hajjar, DP; Lindenbaum, R; Mittar, D; Resnick, MJ; Upmacis, RK | 1 |
| Cantoni, O; Guidarelli, A; Tommasini, I | 1 |
| Dikshit, M; Raghavan, SA; Saini, R; Sharma, P | 1 |
| Cantoni, O; Cerioni, L; Guidarelli, A; Tommasini, I | 2 |
| Eliraz, A; Fink, G; Madar, Z; Offer, S; Stark, AH | 1 |
| Cantoni, O; Fiorani, M; Guidarelli, A; Palomba, L | 1 |
| Chakraborti, S; Chakraborti, T; Das, S | 1 |
| Brüne, B; Cantoni, O; Cerioni, L; Guidarelli, A; Tommasini, I | 1 |
| Cantoni, O; Carloni, E; Cerioni, L; Guidarelli, A; Palomba, L; Tommasini, I | 1 |
| Brüne, B; Cantoni, O; Cerioni, L; Fiorani, M; Guidarelli, A; Tommasini, I | 1 |
| Deeb, RS; Hajjar, DP; Upmacis, RK | 1 |
| Cantoni, O; Cerioni, L; Guidarelli, A; Palomba, L; Tommasini, I | 1 |
| Cantoni, O; Cerioni, L | 1 |
| Borutaite, V; Brown, GC; Hope, H | 1 |
| Amadori, A; Cantoni, O; Palomba, L | 1 |
| Cantoni, O; Cerioni, L; Tommasini, I | 1 |
| Hein, TW; Kuo, L; Qamirani, E; Ren, Y | 1 |
| Cantoni, O; Cerioni, L; Palomba, L | 2 |
| Cheung, C; Deeb, RS; Gross, SS; Hajjar, DP; Lamon, BD; Nuriel, T; Upmacis, RK | 1 |
| Chen, YJ; Quilley, J; Santos, M | 1 |
| Niemann, J; Tsikas, D | 1 |
| Boggia, J; Cassina, A; Peluffo, G; Radi, R; Rios, N; Rubbo, H; Sánchez-Calvo, B; Trostchansky, A | 1 |
| Alvarado-Coutiño, LK; Escalante, B; Gámez-Méndez, AM; López-Vaquera, SR; Ríos, A; Villa-Martínez, E | 1 |
3 review(s) available for peroxynitrous acid and arachidonic acid
| Article | Year |
|---|---|
Nitric oxide and renal and cardiac dysfunction in cirrhosis.
Topics: Animals; Arachidonic Acid; Body Water; Cardiomyopathies; Humans; Kidney Diseases; Liver Cirrhosis; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Peroxynitrous Acid; Rats; Sodium Channels | 2002 |
Survival pathways triggered by peroxynitrite in cells belonging to the monocyte/macrophage lineage.
Topics: Animals; Apoptosis; Arachidonic Acid; Cell Death; Cell Lineage; Cell Survival; Cytosol; Humans; Hydrogen Peroxide; Inflammation; Macrophages; Mitochondria; Models, Biological; Monocytes; Necrosis; Peroxynitrous Acid; Phospholipases A; Protein Isoforms; Signal Transduction; Time Factors; U937 Cells | 2005 |
Oxidative alterations of cyclooxygenase during atherogenesis.
Topics: Animals; Arachidonic Acid; Atherosclerosis; Cyclooxygenase Inhibitors; Cysteine; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Enzyme Activation; Heme; Humans; Intramolecular Oxidoreductases; MAP Kinase Signaling System; Nitric Oxide; Nitrogen Oxides; Oxidation-Reduction; Peroxynitrous Acid; Prostaglandin-Endoperoxide Synthases; Tyrosine | 2006 |
27 other study(ies) available for peroxynitrous acid and arachidonic acid
| Article | Year |
|---|---|
CX-659S: a novel diaminouracil derivative that has antioxidative and acute anti-inflammatory activities.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Arachidonic Acid; Ascorbic Acid; Chromans; Dose-Response Relationship, Drug; Ear; Edema; Lipid Peroxidation; Male; Mice; Mice, Inbred ICR; Oxidation-Reduction; Peroxynitrous Acid; Rats; Rats, Sprague-Dawley; Tetradecanoylphorbol Acetate; Uracil | 2002 |
Pivotal role of superoxides generated in the mitochondrial respiratory chain in peroxynitrite-dependent activation of phospholipase A2.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Animals; Arachidonic Acid; Calcimycin; Dose-Response Relationship, Drug; Electron Transport; Enzyme Inhibitors; Ionophores; Microscopy, Confocal; Mitochondria; Oxygen; PC12 Cells; Peroxynitrous Acid; Phospholipases A; Phospholipases A2; Protein Isoforms; Quinacrine; Rats; Reactive Oxygen Species | 2002 |
Peroxynitrite stimulates the activity of cytosolic phospholipase A2 in U937 cells: the extent of arachidonic acid formation regulates the balance between cell survival or death.
Topics: Arachidonic Acid; Arachidonic Acids; Cell Death; Cell Survival; Cytosol; Enzyme Inhibitors; Eukaryotic Cells; Humans; Oligonucleotides, Antisense; Peroxynitrous Acid; Phospholipases A; Phospholipases A2; Tumor Cells, Cultured | 2002 |
Involvement of the mitogen-activated protein kinase cascade in peroxynitrite-mediated arachidonic acid release in vascular smooth muscle cells.
Topics: Animals; Arachidonic Acid; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Chelating Agents; Dinoprostone; Enzyme Inhibitors; Group IV Phospholipases A2; MAP Kinase Signaling System; Mitogen-Activated Protein Kinases; Molsidomine; Muscle, Smooth, Vascular; Nitric Oxide; p38 Mitogen-Activated Protein Kinases; Peroxynitrous Acid; Phospholipases A; Rats | 2004 |
Non-toxic concentrations of peroxynitrite commit U937 cells to mitochondrial permeability transition-dependent necrosis that is however prevented by endogenous arachidonic acid.
Topics: Arachidonic Acid; Cell Death; Cell Division; Cytoprotection; DNA; Humans; Kinetics; Mitochondria; Necrosis; Permeability; Peroxynitrous Acid; U937 Cells | 2004 |
Ascorbate-mediated enhancement of reactive oxygen species generation from polymorphonuclear leukocytes: modulatory effect of nitric oxide.
Topics: Animals; Apoptosis; Arachidonic Acid; Ascorbic Acid; Cells, Cultured; Dehydroascorbic Acid; Escherichia coli; Free Radical Scavengers; Humans; Macaca mulatta; Male; NADPH Oxidases; Neutrophils; Nitric Oxide; Nitric Oxide Synthase; Oxidation-Reduction; Oxygen; Peroxynitrous Acid; Phagocytosis; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species | 2004 |
The arachidonate-dependent cytoprotective signaling evoked by peroxynitrite is a general response of the monocyte/macrophage lineage.
Topics: Animals; Arachidonic Acid; Cell Line; Cell Membrane Permeability; Cytoprotection; Dose-Response Relationship, Drug; Humans; Macrophages; Mitochondria; Monocytes; Peroxynitrous Acid; Rats; Signal Transduction | 2004 |
Hydrogen peroxide generated at the level of mitochondria in response to peroxynitrite promotes U937 cell death via inhibition of the cytoprotective signalling mediated by cytosolic phospholipase A2.
Topics: Antimycin A; Arachidonic Acid; Blotting, Western; Catalase; Cell Death; Cytosol; Dose-Response Relationship, Drug; Enzyme Inhibitors; Humans; Hydrogen Peroxide; Immunohistochemistry; Microscopy, Confocal; Mitochondria; Necrosis; Oligonucleotides; Oligonucleotides, Antisense; Oxygen Consumption; Peroxynitrous Acid; Phospholipases A; Phospholipases A2; Rotenone; Signal Transduction; Temperature; Transfection; U937 Cells | 2004 |
Interactions between nitric oxide and arachidonic acid in lung epithelial cells: possible roles for peroxynitrite and superoxide.
Topics: Animals; Arachidonic Acid; Cell Line, Transformed; Dose-Response Relationship, Drug; Enzyme Inhibitors; Lung; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Peroxynitrous Acid; Phospholipases A; Phospholipases A2; Rats; Respiratory Mucosa; Signal Transduction; Superoxides | 2005 |
U937 cell necrosis mediated by peroxynitrite is not caused by depletion of ATP and is prevented by arachidonate via an ATP-dependent mechanism.
Topics: Adenosine Triphosphate; Apoptosis; Arachidonic Acid; Dose-Response Relationship, Drug; Humans; Monocytes; Necrosis; Peroxynitrous Acid; U937 Cells | 2005 |
ERK1/2-dependent regulation of U937 cell survival after exposure to peroxynitrite.
Topics: Animals; Arachidonic Acid; Butadienes; Cell Survival; Culture Media; Flavonoids; Humans; Intracellular Signaling Peptides and Proteins; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Nitriles; PC12 Cells; Peroxynitrous Acid; Rats; U937 Cells | 2005 |
Proteolytic activation of protein kinase Calpha by peroxynitrite in stimulating cytosolic phospholipase A2 in pulmonary endothelium: involvement of a pertussis toxin sensitive protein.
Topics: Animals; Arachidonic Acid; Calcium Signaling; Cattle; Cells, Cultured; Cytosol; Endothelium, Vascular; Enzyme Activation; GTP-Binding Protein alpha Subunits, Gi-Go; Models, Biological; Peptide Hydrolases; Peroxynitrous Acid; Pertussis Toxin; Phospholipases A; Phospholipases A2; Protein Kinase C; Protein Kinase C-alpha; Proteins; Pulmonary Artery | 2005 |
A downstream role for protein kinase Calpha in the cytosolic phospholipase A2-dependent protective signalling mediated by peroxynitrite in U937 cells.
Topics: Arachidonic Acid; Blotting, Western; Cell Death; Cell Survival; Cytosol; Down-Regulation; Enzyme Inhibitors; Fluoresceins; Fluorescent Dyes; Humans; Immunohistochemistry; Leukocytes, Mononuclear; Oligonucleotides, Antisense; Peroxynitrous Acid; Phospholipases A; Phospholipases A2; Protein Kinase C; Protein Kinase C-alpha; Rhodamine 123; Signal Transduction; Tetradecanoylphorbol Acetate; Transfection; Tritium; Tumor Cells, Cultured; U937 Cells | 2005 |
Role of Bcl-2 in the arachidonate-mediated survival signaling preventing mitochondrial permeability transition-dependent U937 cell necrosis induced by peroxynitrite.
Topics: Arachidonic Acid; Arsenites; Cell Survival; Cyclic AMP-Dependent Protein Kinase Catalytic Subunits; Cyclic AMP-Dependent Protein Kinases; DNA Damage; Dose-Response Relationship, Drug; Glutathione; Humans; Isoenzymes; Mitochondria; Necrosis; Oxidation-Reduction; Peroxynitrous Acid; Proto-Oncogene Proteins c-bcl-2; Signal Transduction; U937 Cells | 2005 |
5-Hydroxyeicosatetraenoic acid is a key intermediate of the arachidonate-dependent protective signaling in monocytes/macrophages exposed to peroxynitrite.
Topics: Arachidonate 5-Lipoxygenase; Arachidonic Acid; Cell Death; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Humans; Hydroxyeicosatetraenoic Acids; Leukocytes, Mononuclear; Lipoxygenase Inhibitors; Macrophages; Masoprocol; Mitochondria; Peroxynitrous Acid; Protein Kinase C-alpha; Signal Transduction; Structure-Activity Relationship; U937 Cells | 2006 |
ERK1/2 regulates two sequential steps promoting monocyte survival to peroxynitrite.
Topics: Arachidonate 5-Lipoxygenase; Arachidonic Acid; bcl-2-Associated X Protein; bcl-Associated Death Protein; Cell Survival; Cyclosporine; Cytochromes c; Enzyme Activation; Enzyme Inhibitors; Humans; Hydroxyeicosatetraenoic Acids; Mitochondria; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Monocytes; Peroxynitrous Acid; Phospholipases A; Phosphorylation; Protein Kinase C-alpha; Protein Transport; U937 Cells | 2007 |
Arachidonate and NADPH oxidase synergise with iNOS to induce death in macrophages: mechanisms of inflammatory degeneration.
Topics: Animals; Arachidonic Acid; Cell Death; Cell Line; Inflammation; Macrophages; Mice; NADPH Oxidases; Necrosis; Nitric Oxide Synthase Type II; Peroxynitrous Acid | 2006 |
Early release of arachidonic acid prevents an otherwise immediate formation of toxic levels of peroxynitrite in astrocytes stimulated with lipopolysaccharide/interferon-gamma.
Topics: Animals; Animals, Newborn; Apoptosis; Arachidonic Acid; Astrocytes; Cell Survival; Cells, Cultured; Cytoprotection; Encephalitis; Gene Expression Regulation; Inflammation Mediators; Interferon-gamma; Lipopolysaccharides; NF-kappa B; Nitric Oxide; Nitric Oxide Synthase Type I; Peroxynitrous Acid; Rats; Rats, Sprague-Dawley; Signal Transduction; Superoxides | 2007 |
The arachidonate-dependent survival signaling preventing toxicity in monocytes/macrophages exposed to peroxynitrite.
Topics: Arachidonic Acid; Cell Survival; Humans; Macrophages; Monocytes; Peroxynitrous Acid; Signal Transduction; U937 Cells | 2008 |
C-reactive protein impairs coronary arteriolar dilation to prostacyclin synthase activation: role of peroxynitrite.
Topics: Animals; Arachidonic Acid; Arterioles; C-Reactive Protein; Cell Separation; Cytochrome P-450 Enzyme System; Enzyme Activation; Epoprostenol; Immunohistochemistry; Intramolecular Oxidoreductases; Nitric Oxide; Nitroprusside; Peroxynitrous Acid; Serotonin; Sus scrofa; Tyrosine; Vasodilation; Vasomotor System | 2009 |
Arachidonic acid: a key molecule for astrocyte survival to peroxynitrite.
Topics: Adenosine Triphosphate; Analysis of Variance; Animals; Animals, Newborn; Arachidonic Acid; Arachidonic Acids; Astrocytes; Caspase 3; Cell Survival; Cells, Cultured; Cerebellum; Cerebral Cortex; Cytochromes c; Dose-Response Relationship, Drug; Enzyme Inhibitors; Fluoresceins; Membrane Potential, Mitochondrial; Neurons; Oligodeoxyribonucleotides, Antisense; Peroxynitrous Acid; Phospholipases A2; Rats; Rats, Sprague-Dawley; Time Factors; Transfection | 2009 |
Physical evidence for substrate binding in preventing cyclooxygenase inactivation under nitrative stress.
Topics: Amino Acid Sequence; Animals; Arachidonic Acid; Catalytic Domain; Chromatography, High Pressure Liquid; Chromatography, Liquid; Cyclooxygenase 1; Cyclooxygenase Inhibitors; Electrochemistry; Enzyme Activation; Heme; Humans; Mice; Molecular Sequence Data; Peroxynitrous Acid; Prostaglandin-Endoperoxide Synthases; Protein Binding; Protein Multimerization; Protein Structure, Quaternary; Rats; Stress, Physiological; Substrate Specificity; Tandem Mass Spectrometry; Tyrosine | 2010 |
Arachidonic acid inhibits neuronal nitric oxide synthase elicited by proinflammatory stimuli and promotes astrocyte survival with both exogenous and endogenous peroxynitrite via different mechanisms.
Topics: Animals; Animals, Newborn; Arachidonic Acid; Astrocytes; Blotting, Western; Cell Survival; Cells, Cultured; Cerebral Cortex; Enzyme Inhibitors; Immunohistochemistry; Inflammation; Lipoxygenase; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type I; Peroxynitrous Acid; Protein Tyrosine Phosphatases; Rats; Rats, Sprague-Dawley; Signal Transduction; Tyrosine | 2010 |
Treatment of diabetic rats with a peroxynitrite decomposition catalyst prevents induction of renal COX-2.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Arachidonic Acid; Cells, Cultured; Creatinine; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Diabetes Mellitus, Experimental; Dinoprostone; Humans; Kidney; Male; Metalloporphyrins; Peroxynitrous Acid; Rats; Rats, Wistar; Transforming Growth Factor beta; Tumor Necrosis Factor-alpha; Tyrosine | 2011 |
Nitric oxide, peroxynitrite, S-nitrosothiols and thiols are unlikely to exert their effects on recombinant cyclooxygenase-1 and cyclooxygenase-2 activity in vitro by modifying cysteine moieties.
Topics: Arachidonic Acid; Blood Platelets; Cyclooxygenase 1; Cyclooxygenase 2; Cysteine; Ethylmaleimide; Humans; Nitric Oxide; Peroxynitrous Acid; Recombinant Proteins; S-Nitrosothiols | 2012 |
Nitro-Arachidonic Acid Prevents Angiotensin II-Induced Mitochondrial Dysfunction in a Cell Line of Kidney Proximal Tubular Cells.
Topics: Adenosine Triphosphatases; Angiotensin II; Arachidonic Acid; Cell Line; Humans; Kidney Tubules, Proximal; Mitochondria; Models, Biological; Nitric Oxide Synthase; Oxidation-Reduction; Peroxynitrous Acid; Succinate Dehydrogenase; Superoxides | 2016 |
Thromboxane-dependent coronary vasoconstriction in obese mice: Role of peroxynitrite.
Topics: Animals; Arachidonic Acid; Cyclooxygenase 2; Mice; Mice, Inbred C57BL; Mice, Obese; Obesity; Peroxynitrous Acid; Thromboxane A2; Thromboxanes; Vasoconstriction | 2022 |