Page last updated: 2024-09-03

peroxynitrous acid and angiotensin ii

peroxynitrous acid has been researched along with angiotensin ii in 28 studies

Compound Research Comparison

Studies
(peroxynitrous acid)
Trials
(peroxynitrous acid)
Recent Studies (post-2010)
(peroxynitrous acid)
Studies
(angiotensin ii)
Trials
(angiotensin ii)
Recent Studies (post-2010) (angiotensin ii)
3,303211,23038,1521,0897,413

Protein Interaction Comparison

ProteinTaxonomyperoxynitrous acid (IC50)angiotensin ii (IC50)
Atrial natriuretic peptide receptor 3Homo sapiens (human)0.002
Type-1A angiotensin II receptor Rattus norvegicus (Norway rat)0.002
Type-1B angiotensin II receptorRattus norvegicus (Norway rat)0.0018
Type-1 angiotensin II receptorHomo sapiens (human)0.0055
Type-2 angiotensin II receptorRattus norvegicus (Norway rat)0.004
Type-2 angiotensin II receptorHomo sapiens (human)0.0011

Research

Studies (28)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's18 (64.29)29.6817
2010's10 (35.71)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Arenas, IA; Davidge, ST; Gragasin, FS; Kainth, N; Xu, Y1
Bachschmid, M; Thurau, S; Ullrich, V; Zou, MH1
Calò, LA; Davis, PA; Pagnin, E; Sartori, M; Semplicini, A1
Andersen, TT; Bhatt, N; Crawford, DR; Davies, KK; Ermak, G; Lin, HY; Michtalik, HJ; Nachod, S; Narayan, AV; Petti, LM; Van Riper, DA; Zhang, S1
Hano, T; Imanishi, T; Nishio, I2
Brandes, RP; Brandt, U; Dröse, S; Fleming, I; Keller, A; Mohamed, A1
Aslam, S; Borrego, L; Chabrashvili, T; Umans, JG; Wang, D1
Anrather, J; Girouard, H; Iadecola, C; Park, L; Zhou, P1
Hayashi, Y; Kamata, K; Kobayashi, T; Matsumoto, T; Taguchi, K1
Beretz, A; Etienne-Selloum, N; Kane, MO; Sarr, M; Schini-Kerth, VB; Walter, A1
Doi, K; Fujita, T; Homma, T; Isobe, H; Maeda, R; Nakamura, E; Negishi, K; Noiri, E; Tanaka, T1
Akasaka, T; Ikejima, H; Imanishi, T; Kobayashi, K; Kuroi, A1
Szabo, C1
Kagota, S; Kunitomo, M; Nakamura, K; Nejime, N; Shinozuka, K; Tada, Y1
Bibert, S; Chia, KK; Cornelius, F; Figtree, GA; Garcia, A; Geering, K; Hamilton, EJ; Liu, CC; Rasmussen, HH; White, CN1
Song, P; Wang, S; Wu, Y; Xu, J; Zou, MH1
Lodhia, P; Luong, MW; Rabkin, SW1
Daiber, A; Hortmann, M; Jansen, T; Karbach, S; Knorr, M; Münzel, T; Oelze, M; Opitz, B; Schell, R; Schuhmacher, S; Steven, S; Wenzel, P1
Daiber, A; Foretz, M; Hortmann, M; Jansen, T; Keaney, JF; Kleschyov, AL; Knorr, M; Lackner, K; Münzel, T; Oelze, M; Schuhmacher, S; Schulz, E; Viollet, B; Wegener, G; Wenzel, P1
Kobori, H; Lara, LS; Majid, DS; McCormack, M; Navar, LG; Prieto, MC; Semprum-Prieto, LC; Shenouda, S1
Yu, YS; Zheng, H1
Davidge, ST; Gao, PJ; Jiang, YY; Jin, HY; Kassiri, Z; Ning, G; Oudit, GY; Penninger, JM; Song, B; Yu, HM; Zhong, JC; Zhu, DL1
Block, K; Eid, AA; Ghosh-Choudhury, G; Gorin, Y; Khazim, K; Lee, DY; Roman, LJ; Wauquier, F1
Belhomme, M; Buzzacott, P; Guerrero, F; Lambrechts, K; Mazur, A; Theron, M; Wang, Q1
Boggia, J; Cassina, A; Peluffo, G; Radi, R; Rios, N; Rubbo, H; Sánchez-Calvo, B; Trostchansky, A1
Freeman, BA; Hudmon, A; Johnson, DE; Levitan, ES; Ramaswamy, SS; Schopfer, FJ; Vitturi, DA; Zhou, C1
da Silva, CH; de Oliveira, AM; do Prado, AF; Gomes, MS; Moreira, JD; Moreira, RP; Pernomian, L1

Reviews

1 review(s) available for peroxynitrous acid and angiotensin ii

ArticleYear
Role of nitrosative stress in the pathogenesis of diabetic vascular dysfunction.
    British journal of pharmacology, 2009, Volume: 156, Issue:5

    Topics: Aldehyde Reductase; Angiotensin II; Animals; Diabetic Angiopathies; Drug Therapy, Combination; Endothelium, Vascular; Enzyme Activation; Glucose; Glycation End Products, Advanced; Humans; Oxidative Stress; Peroxynitrous Acid; Poly Adenosine Diphosphate Ribose; Protein Kinase C; Reactive Nitrogen Species; Reactive Oxygen Species; Signal Transduction

2009

Other Studies

27 other study(ies) available for peroxynitrous acid and angiotensin ii

ArticleYear
Estrogen reduces angiotensin II-induced nitric oxide synthase and NAD(P)H oxidase expression in endothelial cells.
    Arteriosclerosis, thrombosis, and vascular biology, 2003, Jan-01, Volume: 23, Issue:1

    Topics: Angiotensin II; Animals; Capillaries; Cattle; Cell Line; Coronary Vessels; Endothelium, Vascular; Enzyme Induction; Estradiol; NADH, NADPH Oxidoreductases; NADPH Oxidases; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Peroxynitrous Acid

2003
Endothelial cell activation by endotoxin involves superoxide/NO-mediated nitration of prostacyclin synthase and thromboxane receptor stimulation.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2003, Volume: 17, Issue:8

    Topics: 6-Ketoprostaglandin F1 alpha; Angiotensin II; Animals; Cattle; Coronary Vasospasm; Coronary Vessels; Cytochrome P-450 Enzyme System; Endothelium, Vascular; In Vitro Techniques; Intramolecular Oxidoreductases; Lipopolysaccharides; Nitrates; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Peroxynitrous Acid; Polyethylene Glycols; Prostaglandin Endoperoxides; Receptors, Thromboxane; Superoxide Dismutase; Superoxides; Vasoconstriction; Vasodilation; Xanthine Oxidase

2003
Oxidative stress-related factors in Bartter's and Gitelman's syndromes: relevance for angiotensin II signalling.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2003, Volume: 18, Issue:8

    Topics: Adult; Angiotensin II; Bartter Syndrome; Female; Humans; Inositol Polyphosphate 5-Phosphatases; Male; Membrane Transport Proteins; Middle Aged; NADPH Dehydrogenase; NADPH Oxidases; Oxidative Stress; Peroxynitrous Acid; Phosphoproteins; Phosphoric Monoester Hydrolases; Polymerase Chain Reaction; Reactive Oxygen Species; Signal Transduction; Transforming Growth Factor beta

2003
Oxidative and calcium stress regulate DSCR1 (Adapt78/MCIP1) protein.
    Free radical biology & medicine, 2003, Sep-01, Volume: 35, Issue:5

    Topics: Angiotensin II; Antifibrinolytic Agents; Astrocytoma; Calcineurin; Calcineurin Inhibitors; Calcium; Cell Division; DNA-Binding Proteins; Electrophoretic Mobility Shift Assay; Enzyme Inhibitors; Gene Expression Regulation; Growth Substances; HeLa Cells; Humans; Hydrogen Peroxide; Intracellular Signaling Peptides and Proteins; Ionophores; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Muscle Proteins; Oxidants; Oxidative Stress; Peroxynitrous Acid; Phosphorylation; Protein Tyrosine Phosphatases; Vitamin K 3

2003
Angiotensin II accelerates endothelial progenitor cell senescence through induction of oxidative stress.
    Journal of hypertension, 2005, Volume: 23, Issue:1

    Topics: Angiotensin II; Cell Division; Cellular Senescence; Endothelial Cells; Humans; In Vitro Techniques; Membrane Glycoproteins; NADPH Oxidase 2; NADPH Oxidases; Oxidative Stress; Peroxynitrous Acid; Receptor, Angiotensin, Type 1; Telomerase; Vascular Endothelial Growth Factor A; Vasoconstrictor Agents

2005
Analysis of dichlorodihydrofluorescein and dihydrocalcein as probes for the detection of intracellular reactive oxygen species.
    Free radical research, 2004, Volume: 38, Issue:12

    Topics: Angiotensin II; Animals; Aorta; Cells, Cultured; Cytoplasm; Electron Spin Resonance Spectroscopy; Electron Transport Complex I; Fluoresceins; Fluorescent Dyes; Half-Life; Mitochondria; Myocytes, Smooth Muscle; Oxidative Stress; Peroxidase; Peroxynitrous Acid; Rats; Reactive Oxygen Species

2004
Estrogen reduces angiotensin II-induced acceleration of senescence in endothelial progenitor cells.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2005, Volume: 28, Issue:3

    Topics: Angiotensin II; Cells, Cultured; Cellular Senescence; Down-Regulation; Drug Interactions; Endothelium, Vascular; Estrogens; Humans; Membrane Glycoproteins; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; NADPH Oxidase 2; NADPH Oxidases; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Peroxynitrous Acid; Phosphorylation; Receptor, Angiotensin, Type 1; Stem Cells; Telomerase; Vasoconstrictor Agents

2005
Angiotensin II infusion alters vascular function in mouse resistance vessels: roles of O and endothelium.
    Journal of vascular research, 2006, Volume: 43, Issue:1

    Topics: Angiotensin II; Animals; Arterioles; Biological Factors; Blood Pressure; Endothelium-Dependent Relaxing Factors; Endothelium, Vascular; Hypertension; Male; Membrane Transport Proteins; Mesenteric Arteries; Mice; Mice, Inbred C57BL; NADP; NADPH Oxidases; Nitric Oxide; Oxidative Stress; Peroxynitrous Acid; Phosphoproteins; RNA, Messenger; Superoxides; Vascular Resistance; Vasoconstriction; Vasoconstrictor Agents

2006
Cerebrovascular nitrosative stress mediates neurovascular and endothelial dysfunction induced by angiotensin II.
    Arteriosclerosis, thrombosis, and vascular biology, 2007, Volume: 27, Issue:2

    Topics: Acetylcholine; Adenosine; Angiotensin II; Animals; Cerebrovascular Circulation; Endothelium, Vascular; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrosation; Peroxynitrous Acid; Reactive Oxygen Species; Superoxides; Tyrosine; Vasodilator Agents; Vibrissae

2007
Enalapril improves impairment of SERCA-derived relaxation and enhancement of tyrosine nitration in diabetic rat aorta.
    European journal of pharmacology, 2007, Feb-05, Volume: 556, Issue:1-3

    Topics: Acetylcholine; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Aorta, Thoracic; Blood Glucose; Blood Pressure; Diabetes Mellitus, Experimental; Enalapril; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide; Peroxynitrous Acid; Rats; Rats, Wistar; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Thapsigargin; Tyrosine

2007
Angiotensin II induces the vascular expression of VEGF and MMP-2 in vivo: preventive effect of red wine polyphenols.
    Journal of vascular research, 2008, Volume: 45, Issue:5

    Topics: Angiotensin II; Animals; Antihypertensive Agents; Aorta; Blood Pressure; Blotting, Western; Disease Models, Animal; Enzyme Inhibitors; Flavonoids; Fluorescent Antibody Technique; Hypertension; Male; Matrix Metalloproteinase 2; Metalloporphyrins; Nitric Oxide; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Nitroarginine; Peroxynitrous Acid; Phenols; Polyphenols; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Time Factors; Up-Regulation; Vascular Endothelial Growth Factor A; Wine

2008
A water-soluble fullerene vesicle alleviates angiotensin II-induced oxidative stress in human umbilical venous endothelial cells.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2008, Volume: 31, Issue:1

    Topics: Adult; Angiotensin II; Apoptosis; Cell Line; Cell Survival; Chemical Phenomena; Chemistry, Physical; Endothelial Cells; Female; Flow Cytometry; Fluorescein; Fluoresceins; Fluorescent Dyes; Fullerenes; Humans; Hydroxyl Radical; Immunohistochemistry; Microscopy, Electron, Transmission; Oxidants; Oxidative Stress; Peroxynitrous Acid; Pregnancy; Reactive Oxygen Species; Solubility; Umbilical Veins

2008
Pioglitazone inhibits angiotensin II-induced senescence of endothelial progenitor cell.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2008, Volume: 31, Issue:4

    Topics: Angiotensin II; Cells, Cultured; Cellular Senescence; Drug Interactions; Gene Expression; Hematopoietic Stem Cells; Humans; Hypertension; Hypoglycemic Agents; Membrane Glycoproteins; NADPH Oxidase 2; NADPH Oxidases; Oxidative Stress; Peroxynitrous Acid; Pioglitazone; Receptor, Angiotensin, Type 1; Superoxides; Telomerase; Thiazolidinediones; Vasoconstrictor Agents

2008
Chronic production of peroxynitrite in the vascular wall impairs vasorelaxation function in SHR/NDmcr-cp rats, an animal model of metabolic syndrome.
    Journal of pharmacological sciences, 2009, Volume: 109, Issue:4

    Topics: Acetylcholine; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Benzimidazoles; Benzoates; Blood Vessels; Blotting, Western; Enzyme Activation; Immunoenzyme Techniques; Luminescence; Male; Metabolic Syndrome; NADPH Oxidases; Nitric Oxide Synthase Type III; Nitroprusside; Peroxynitrous Acid; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Telmisartan; Tyrosine; Vasoconstrictor Agents; Vasodilation

2009
Reversible oxidative modification: a key mechanism of Na+-K+ pump regulation.
    Circulation research, 2009, Jul-17, Volume: 105, Issue:2

    Topics: Adenosine Triphosphatases; Angiotensin II; Animals; Cation Transport Proteins; Cell Adhesion Molecules, Neuronal; Cysteine; Glutaredoxins; Glutathione; Humans; Kidney; Kinetics; Male; Mutation; Myocytes, Cardiac; NADPH Oxidases; Oocytes; Oxidation-Reduction; Paraquat; Peroxynitrous Acid; Protein Conformation; Protein Kinase C; Protein Processing, Post-Translational; Rabbits; Sheep; Signal Transduction; Sodium-Potassium-Exchanging ATPase; Structure-Activity Relationship; Superoxide Dismutase; Swine; Xenopus laevis

2009
Tyrosine nitration of PA700 activates the 26S proteasome to induce endothelial dysfunction in mice with angiotensin II-induced hypertension.
    Hypertension (Dallas, Tex. : 1979), 2009, Volume: 54, Issue:3

    Topics: Angiotensin II; Animals; Aorta; Biopterins; Blood Pressure; Cells, Cultured; Cysteine Proteinase Inhibitors; Endothelial Cells; Endothelium, Vascular; GTP Cyclohydrolase; Humans; Hypertension; In Vitro Techniques; Leupeptins; Mice; Mice, Inbred C57BL; Nitrates; Peroxynitrous Acid; Proteasome Endopeptidase Complex; Proteasome Inhibitors; RNA, Small Interfering; Transfection; Tyrosine; Vasodilation

2009
P38 MAP kinase in valve interstitial cells is activated by angiotensin II or nitric oxide/peroxynitrite, but reduced by Toll-like receptor-2 stimulation.
    The Journal of heart valve disease, 2009, Volume: 18, Issue:6

    Topics: Angiotensin II; Animals; Aortic Valve; Enzyme Activation; Molsidomine; Nitric Oxide; p38 Mitogen-Activated Protein Kinases; Peroxynitrous Acid; Phosphorylation; Receptors, Angiotensin; Signal Transduction; Swine; Toll-Like Receptor 2

2009
Conversion of biliverdin to bilirubin by biliverdin reductase contributes to endothelial cell protection by heme oxygenase-1-evidence for direct and indirect antioxidant actions of bilirubin.
    Journal of molecular and cellular cardiology, 2010, Volume: 49, Issue:2

    Topics: Angiotensin II; Antioxidants; Bilirubin; Biliverdine; Cytoprotection; Endothelial Cells; Free Radical Scavengers; Gene Knockdown Techniques; Gene Silencing; Heme Oxygenase-1; Humans; Leukocytes; Lipopolysaccharides; Mitochondria; Models, Biological; Neutrophils; Nitrosation; Oxidoreductases Acting on CH-CH Group Donors; Peroxynitrous Acid; Reactive Oxygen Species; Respiratory Burst; Tyrosine; Umbilical Veins; Xanthine Oxidase

2010
α1AMP-activated protein kinase preserves endothelial function during chronic angiotensin II treatment by limiting Nox2 upregulation.
    Arteriosclerosis, thrombosis, and vascular biology, 2011, Volume: 31, Issue:3

    Topics: AMP-Activated Protein Kinases; Angiotensin II; Animals; Cyclooxygenase 2; Dose-Response Relationship, Drug; Electron Spin Resonance Spectroscopy; Endothelium, Vascular; Enzyme Activation; Enzyme Inhibitors; Inflammation; Inflammation Mediators; Infusions, Parenteral; Male; Membrane Glycoproteins; Mice; Mice, Knockout; NADPH Oxidase 2; NADPH Oxidases; Nitric Oxide; Nitric Oxide Synthase Type II; Nitrites; Oxidative Stress; Peroxynitrous Acid; RNA, Messenger; Superoxides; Time Factors; Up-Regulation; Vascular Cell Adhesion Molecule-1; Vasodilation; Vasodilator Agents

2011
AT1 receptor-mediated augmentation of angiotensinogen, oxidative stress, and inflammation in ANG II-salt hypertension.
    American journal of physiology. Renal physiology, 2012, Jan-01, Volume: 302, Issue:1

    Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensinogen; Animals; Hypertension; Kidney; Male; NADPH Oxidases; Oxidative Stress; Peroxynitrous Acid; Proteinuria; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Sodium Chloride, Dietary

2012
Chronic hydrogen-rich saline treatment reduces oxidative stress and attenuates left ventricular hypertrophy in spontaneous hypertensive rats.
    Molecular and cellular biochemistry, 2012, Volume: 365, Issue:1-2

    Topics: Angiotensin II; Animals; Antioxidants; Catalase; Cytokines; Electron Transport Chain Complex Proteins; Glutathione Peroxidase; Glutathione Transferase; Heart Ventricles; Hemodynamics; Hydrogen; Hypertension; Hypertrophy, Left Ventricular; Male; Malondialdehyde; Mitochondria, Heart; NADPH Oxidases; NF-kappa B; Oxidative Stress; Peroxynitrous Acid; Random Allocation; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Reactive Oxygen Species; Sodium Chloride; Superoxide Dismutase

2012
ACE2 deficiency enhances angiotensin II-mediated aortic profilin-1 expression, inflammation and peroxynitrite production.
    PloS one, 2012, Volume: 7, Issue:6

    Topics: Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Aorta; Blotting, Western; Chemokine CCL2; Ethidium; Inflammation; Interleukin-1beta; Interleukin-6; Mice; Mice, Knockout; NADPH Oxidases; Peptidyl-Dipeptidase A; Peroxynitrous Acid; Profilins; Real-Time Polymerase Chain Reaction; Tyrosine

2012
Nox4 NADPH oxidase mediates peroxynitrite-dependent uncoupling of endothelial nitric-oxide synthase and fibronectin expression in response to angiotensin II: role of mitochondrial reactive oxygen species.
    The Journal of biological chemistry, 2013, Oct-04, Volume: 288, Issue:40

    Topics: Angiotensin II; Animals; Biological Availability; Fibronectins; Fibrosis; Gene Silencing; Intracellular Space; Mesangial Cells; Mitochondria; Models, Biological; NADPH Oxidase 4; NADPH Oxidases; Nitric Oxide; Nitric Oxide Synthase Type III; Oxidative Stress; Peroxynitrous Acid; Rats; Reactive Oxygen Species; Superoxide Dismutase; Superoxides; Up-Regulation

2013
Antioxidants, endothelial dysfunction, and DCS: in vitro and in vivo study.
    Journal of applied physiology (Bethesda, Md. : 1985), 2015, Dec-15, Volume: 119, Issue:12

    Topics: Acetylcysteine; Angiotensin II; Animals; Antioxidants; Ascorbic Acid; Cell Death; Cell Survival; Cells, Cultured; Decompression Sickness; Diving; Endothelium, Vascular; Glutathione; Male; Nitric Oxide; Oxidative Stress; Peptidyl-Dipeptidase A; Peroxynitrous Acid; Rats; Rats, Sprague-Dawley; Superoxides; Thiobarbituric Acid Reactive Substances

2015
Nitro-Arachidonic Acid Prevents Angiotensin II-Induced Mitochondrial Dysfunction in a Cell Line of Kidney Proximal Tubular Cells.
    PloS one, 2016, Volume: 11, Issue:3

    Topics: Adenosine Triphosphatases; Angiotensin II; Arachidonic Acid; Cell Line; Humans; Kidney Tubules, Proximal; Mitochondria; Models, Biological; Nitric Oxide Synthase; Oxidation-Reduction; Peroxynitrous Acid; Succinate Dehydrogenase; Superoxides

2016
Novel Roles for Peroxynitrite in Angiotensin II and CaMKII Signaling.
    Scientific reports, 2016, Apr-15, Volume: 6

    Topics: Angiotensin II; Animals; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Cell Line; Methionine; Myocytes, Cardiac; Neurons; Oxidation-Reduction; Peroxynitrous Acid; Phosphorylation; Rats; Reactive Oxygen Species; Signal Transduction; Tyrosine

2016
Enhanced nitric oxide generation from nitric oxide synthases as the cause of increased peroxynitrite formation during acute restraint stress: Effects on carotid responsiveness to angiotensinergic stimuli in type-1 diabetic rats.
    European journal of pharmacology, 2016, Jul-15, Volume: 783

    Topics: Angiotensin II; Animals; Behavior, Animal; Carotid Arteries; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Endothelial Cells; Enzyme Activation; Gene Expression Regulation, Enzymologic; Male; Nitric Oxide; Nitric Oxide Synthase; Peroxynitrous Acid; Phenylephrine; Phosphorylation; Rats; Rats, Wistar; Restraint, Physical; Stress, Psychological; Vasoconstriction

2016