Page last updated: 2024-09-03

peroxynitrous acid and amlodipine

peroxynitrous acid has been researched along with amlodipine in 3 studies

Compound Research Comparison

Studies
(peroxynitrous acid)
Trials
(peroxynitrous acid)
Recent Studies (post-2010)
(peroxynitrous acid)
Studies
(amlodipine)
Trials
(amlodipine)
Recent Studies (post-2010) (amlodipine)
3,303211,2304,2001,5041,671

Protein Interaction Comparison

ProteinTaxonomyperoxynitrous acid (IC50)amlodipine (IC50)
Voltage-dependent L-type calcium channel subunit alpha-1CCavia porcellus (domestic guinea pig)1.2
Potassium channel subfamily K member 2Homo sapiens (human)0.4
Alpha-2A adrenergic receptorHomo sapiens (human)0.602
Alpha-2C adrenergic receptorHomo sapiens (human)1.8
5-hydroxytryptamine receptor 6Homo sapiens (human)2.898
Sodium-dependent dopamine transporter Homo sapiens (human)5.521
Voltage-dependent L-type calcium channel subunit alpha-1CHomo sapiens (human)2.7
Potassium channel subfamily K member 2 Bos taurus (cattle)0.43

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (66.67)29.6817
2010's1 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Day, CA; Funovics, P; Heeba, G; Jacob, RF; Kubant, R; Malinski, T; Mason, RP; Medlin, YS1
Kagota, S; Kubota, Y; Kunitomo, M; Nakamura, K; Nejime, N; Shinozuka, K; Tada, Y; Yamaguchi, Y1
Corbalan, JJ; Jacob, RF; Kaliszan, R; Malinski, T; Mason, RP1

Other Studies

3 other study(ies) available for peroxynitrous acid and amlodipine

ArticleYear
Synergistic effect of amlodipine and atorvastatin in reversing LDL-induced endothelial dysfunction.
    Pharmaceutical research, 2008, Volume: 25, Issue:8

    Topics: Amlodipine; Atorvastatin; Blotting, Western; Calcium Channel Blockers; Cells, Cultured; Drug Synergism; Endothelium, Vascular; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lipid Bilayers; Lipoproteins, LDL; Membrane Lipids; Nitric Oxide; Nitric Oxide Synthase Type III; Peroxynitrous Acid; Pyrroles; Vascular Diseases; X-Ray Diffraction

2008
Peroxynitrite is Involved in the dysfunction of vasorelaxation in SHR/NDmcr-cp rats, spontaneously hypertensive obese rats.
    Journal of cardiovascular pharmacology, 2007, Volume: 50, Issue:6

    Topics: Acetylcholine; Amlodipine; Animals; Aorta, Thoracic; Blood Glucose; Blood Pressure; Blotting, Western; Cholesterol; Cyclic GMP; Dose-Response Relationship, Drug; Heart Rate; Hypertension; Imidazoles; In Vitro Techniques; Insulin; Male; Nitric Oxide Synthase Type III; Nitroprusside; Obesity; Peroxynitrous Acid; Rats; Rats, Inbred SHR; Rats, Mutant Strains; Triglycerides; Vasodilation

2007
Amlodipine increased endothelial nitric oxide and decreased nitroxidative stress disproportionately to blood pressure changes.
    American journal of hypertension, 2014, Volume: 27, Issue:3

    Topics: Amlodipine; Animals; Antihypertensive Agents; Aorta; Blood Pressure; Disease Models, Animal; Endothelial Cells; Hypertension; Kidney Glomerulus; Male; Nitric Oxide; Nitric Oxide Synthase Type III; Oxidative Stress; Peroxynitrous Acid; Rats; Rats, Inbred SHR; Time Factors

2014