peroxynitrous acid has been researched along with allopurinol in 33 studies
| Studies (peroxynitrous acid) | Trials (peroxynitrous acid) | Recent Studies (post-2010) (peroxynitrous acid) | Studies (allopurinol) | Trials (allopurinol) | Recent Studies (post-2010) (allopurinol) |
|---|---|---|---|---|---|
| 3,303 | 21 | 1,230 | 15,096 | 743 | 3,363 |
| Protein | Taxonomy | peroxynitrous acid (IC50) | allopurinol (IC50) |
|---|---|---|---|
| Xanthine dehydrogenase/oxidase [Includes: Xanthine dehydrogenase | Rattus norvegicus (Norway rat) | 3.3765 | |
| Xanthine dehydrogenase/oxidase | Homo sapiens (human) | 3.1861 | |
| Xanthine dehydrogenase/oxidase | Bos taurus (cattle) | 5.0758 | |
| Histamine H3 receptor | Cavia porcellus (domestic guinea pig) | 8.69 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 24 (72.73) | 29.6817 |
| 2010's | 8 (24.24) | 24.3611 |
| 2020's | 1 (3.03) | 2.80 |
| Authors | Studies |
|---|---|
| Demiryurek, AT; Gunaydin, B | 2 |
| Daiber, A; Frein, D; Namgaladze, D; Ullrich, V | 1 |
| Baxter, GF; CsonkA, C; Csont, T; Dux, L; Ferdinandy, P; Görbe, A; Onody, A; Schulz, R | 1 |
| Csont, T; Ferdinandy, P; Khadour, FH; Lalu, MM; Panas, D; Schulz, R; Schulze, C; Wildhirt, SM | 1 |
| Blake, DR; Bodamyali, T; Kanczler, JM; Millar, TM; Stevens, CR | 1 |
| Coffey, MJ; Peters-Golden, M; Phare, SM | 1 |
| Beckman, JS; Parks, DA; Teng, RJ; Ye, YZ | 1 |
| Akaike, M; Azuma, H; Iuchi, T; Matsumoto, T; Mitsui, T; Ohshima, Y; Shintani, Y | 1 |
| Choa, EJ; Park, JC; Rhyu, DY; Yokozawa, T | 1 |
| Bachschmid, M; Thurau, S; Ullrich, V; Zou, MH | 1 |
| Elstner, EF; Schempp, H; Toth, A; Weiser, D | 1 |
| André d'Avignon, D; Byun, J; Heinecke, JW; Henderson, JP; Yeh, GC | 1 |
| Deen, WM; Wang, C | 1 |
| Ohshima, H; Saleem, M | 1 |
| Millar, TM | 1 |
| Halliwell, B; Jenner, A; Peng, ZF; Tang, SY; Whiteman, M; Yong, EL | 1 |
| Bachschmid, M; Dormeneva, EV; Galkina, SI; Pushkareva, MA; Sud'ina, GF; Ullrich, V | 1 |
| Fujimoto, Y; Sakuma, S; Uno, E | 1 |
| Bencsik, P; Cakici, I; Csonka, C; Csont, T; Ferdinandy, P; Fodor, G; Giricz, Z; Gyöngyösi, M; Turan, N | 1 |
| Akgoz, M; Cigremis, Y; Erdogan, K; Gaffaroglu, M; Kart, A; Ozen, H; Ozugurlu, F; Turkoz, Y; Tuzcu, M | 1 |
| Batista, MT; Correia, HS; Dinis, TC | 1 |
| Fujii, M; Kohno, S; Mizutani, N; Nabe, T; Yoshino, S | 1 |
| Belmadani, S; Elford, H; Gao, X; Potter, BJ; Wu, J; Xu, X; Zhang, C; Zhang, H | 1 |
| Daiber, A; Hortmann, M; Jansen, T; Karbach, S; Knorr, M; Münzel, T; Oelze, M; Opitz, B; Schell, R; Schuhmacher, S; Steven, S; Wenzel, P | 1 |
| Chen, CC; Hsu, YJ; Lee, TM | 1 |
| Azzolini, C; Cantoni, O; Cerioni, L; Fiorani, M; Guidarelli, A | 1 |
| Black, S; El-Remessy, AB; Ergul, A; Johnson, M; Kumar, S; Owen, MP; Puttabyatappa, Y; Stallone, JN; White, RE | 1 |
| de Boer-Maggard, TR; Mascharak, PK; Resendez, A | 1 |
| Iagupols'kyĭ, IuL; Kotsiuruba, AV; Moĭbenko, OO; Rovenets', RA; Sagach, VF; Strutyns'ka, NA; Strutyns'kyĭ, RB | 1 |
| Ding, Y; Lu, N; Ren, X | 1 |
| Choi, EK; Jee, DL; Jung, H; Kim, S; Kwak, KH; Lim, DG; Lim, JA; Park, JM; Park, SH; Yi, SJ | 1 |
| Nejabati, HR; Roshangar, L | 1 |
2 review(s) available for peroxynitrous acid and allopurinol
| Article | Year |
|---|---|
Xanthine oxidase is a peroxynitrite synthase: newly identified roles for a very old enzyme.
Topics: Animals; Binding Sites; Peroxynitrous Acid; Xanthine Oxidase | 2002 |
Kaempferol: A potential agent in the prevention of colorectal cancer.
Topics: Biological Products; Catalase; Colorectal Neoplasms; Heme Oxygenase-1; Humans; Kaempferols; Peroxynitrous Acid; Reactive Nitrogen Species; Reactive Oxygen Species; Superoxide Dismutase; Superoxides; Xanthine Oxidase | 2022 |
1 trial(s) available for peroxynitrous acid and allopurinol
| Article | Year |
|---|---|
Glucocorticoid excess induces superoxide production in vascular endothelial cells and elicits vascular endothelial dysfunction.
Topics: Adolescent; Adult; Aged; Antioxidants; Autoimmune Diseases; Cells, Cultured; Dexamethasone; Electron Transport; Endothelium, Vascular; Enzyme Inhibitors; Female; Forearm; Glucocorticoids; Humans; Hydrogen Peroxide; Male; Middle Aged; Muscle, Skeletal; NADH, NADPH Oxidoreductases; NADPH Oxidases; Nitric Oxide; Nitric Oxide Donors; Peroxynitrous Acid; Reactive Oxygen Species; Regional Blood Flow; Superoxides; Tyrosine; Vasodilation; Xanthine Oxidase | 2003 |
30 other study(ies) available for peroxynitrous acid and allopurinol
| Article | Year |
|---|---|
Interaction of lidocaine with reactive oxygen and nitrogen species.
Topics: Acridines; Anesthetics, Local; Cell-Free System; Dose-Response Relationship, Drug; Ferrous Compounds; Humans; Hydrogen Peroxide; Hypochlorous Acid; Leukocytes; Lidocaine; Luminescent Measurements; Luminol; N-Formylmethionine Leucyl-Phenylalanine; Oxidants; Peroxynitrous Acid; Reactive Oxygen Species; Xanthine; Xanthine Oxidase | 2001 |
Oxidation and nitrosation in the nitrogen monoxide/superoxide system.
Topics: Animals; Biochemical Phenomena; Biochemistry; Cattle; Chelating Agents; Chromatography, High Pressure Liquid; Chromogenic Compounds; Disulfides; Dose-Response Relationship, Drug; Free Radicals; Hydrazines; Hydrogen Peroxide; Models, Chemical; Molsidomine; Nitric Oxide; Nitric Oxide Donors; Nitrogen; Nitrogen Oxides; Oxygen; Peroxynitrous Acid; Protein Binding; Resorcinols; Spectrophotometry; Spectrum Analysis, Raman; Spermine; Sulfhydryl Compounds; Superoxides; Time Factors; Ultraviolet Rays; Xanthine Oxidase; Zinc | 2002 |
Nitrate tolerance does not increase production of peroxynitrite in the heart.
Topics: Animals; Aorta, Thoracic; Biomarkers; Drug Tolerance; Heart; Heart Ventricles; Hydroxyl Radical; In Vitro Techniques; Male; Myocardium; Nitric Oxide; Nitric Oxide Synthase; Nitroglycerin; Peroxynitrous Acid; Rats; Rats, Wistar; Reactive Oxygen Species; Time; Xanthine Dehydrogenase; Xanthine Oxidase | 2002 |
Enhanced NO and superoxide generation in dysfunctional hearts from endotoxemic rats.
Topics: Animals; Endotoxemia; Heart Diseases; Hydrogen Peroxide; Lipopolysaccharides; Male; Myocardial Contraction; Myocardium; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; Oxygen Consumption; Peroxynitrous Acid; Rats; Rats, Sprague-Dawley; Sepsis; Superoxides; Tyrosine; Xanthine Oxidase | 2002 |
Interaction between nitric oxide, reactive oxygen intermediates, and peroxynitrite in the regulation of 5-lipoxygenase metabolism.
Topics: Animals; Arachidonate 5-Lipoxygenase; Down-Regulation; Female; Free Radical Scavengers; Hydrogen Peroxide; Hydroxyurea; Leukotrienes; Lipopolysaccharides; Lipoxygenase Inhibitors; Macrophages, Alveolar; Nitric Oxide; Peroxynitrous Acid; Rats; Rats, Wistar; Reactive Oxygen Species; Xanthine Oxidase | 2002 |
Urate produced during hypoxia protects heart proteins from peroxynitrite-mediated protein nitration.
Topics: Animals; Ascorbic Acid; Brain; Heart; Hypoxanthine; Hypoxia; In Vitro Techniques; Myocardium; Nitric Oxide; Nitrosation; Peroxynitrous Acid; Rats; Rats, Sprague-Dawley; Tyrosine; Urate Oxidase; Uric Acid; Xanthine Dehydrogenase; Xanthine Oxidase | 2002 |
Prevention of peroxynitrite-induced renal injury through modulation of peroxynitrite production by the Chinese prescription Wen-Pi-Tang.
Topics: Animals; Chromatography, High Pressure Liquid; Creatinine; Drugs, Chinese Herbal; Kidney; Lipid Peroxides; Lipopolysaccharides; Models, Chemical; Nitric Oxide Synthase; Nitrogen; Oxygen; Peroxynitrous Acid; Rats; Rats, Wistar; Reperfusion Injury; Tyrosine; Urea; Xanthine Oxidase | 2002 |
Endothelial cell activation by endotoxin involves superoxide/NO-mediated nitration of prostacyclin synthase and thromboxane receptor stimulation.
Topics: 6-Ketoprostaglandin F1 alpha; Angiotensin II; Animals; Cattle; Coronary Vasospasm; Coronary Vessels; Cytochrome P-450 Enzyme System; Endothelium, Vascular; In Vitro Techniques; Intramolecular Oxidoreductases; Lipopolysaccharides; Nitrates; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Peroxynitrous Acid; Polyethylene Glycols; Prostaglandin Endoperoxides; Receptors, Thromboxane; Superoxide Dismutase; Superoxides; Vasoconstriction; Vasodilation; Xanthine Oxidase | 2003 |
Effects of tetracaine and bupivacaine on chemiluminescence generated by formyl-methionyl-leucyl-phenylalanine-stimulated human leukocytes and cell-free systems.
Topics: Acridines; Anesthetics, Local; Bupivacaine; Cell-Free System; Ferrous Compounds; Free Radicals; Humans; Hydrogen Peroxide; In Vitro Techniques; Leukocytes; Luminescent Measurements; Luminol; N-Formylmethionine Leucyl-Phenylalanine; Peroxynitrous Acid; Tetracaine; Xanthine Oxidase | 2003 |
Antioxidative properties of Iberis amara extracts in biochemical model reactions.
Topics: Adolescent; Adult; alpha-Linolenic Acid; Antioxidants; Brassicaceae; Chromatography, Gas; Ethylenes; Female; Humans; Hydroxyl Radical; In Vitro Techniques; Indicators and Reagents; Light; Lipid Peroxidation; Lipoproteins, LDL; Male; Models, Biological; Oxidation-Reduction; Peroxidase; Peroxynitrous Acid; Plant Extracts; Plants, Medicinal; Rose Bengal; Xanthine Oxidase | 2003 |
8-Nitroxanthine, a product of myeloperoxidase, peroxynitrite, and activated human neutrophils, enhances generation of superoxide by xanthine oxidase.
Topics: Humans; Neutrophil Activation; Neutrophils; Peroxidase; Peroxynitrous Acid; Reperfusion Injury; Superoxides; Xanthine Oxidase; Xanthines | 2003 |
Peroxynitrite delivery methods for toxicity studies.
Topics: Animals; Cells, Cultured; Dimerization; Drug Delivery Systems; Humans; Hypoxanthine; Models, Chemical; Nitrates; Nitric Oxide; Oxidation-Reduction; Peroxynitrous Acid; Toxicity Tests; Tyrosine; Uric Acid; Xanthine Oxidase | 2004 |
Xanthine oxidase converts nitric oxide to nitroxyl that inactivates the enzyme.
Topics: Animals; Cattle; Dose-Response Relationship, Drug; Hemoglobins; Molsidomine; Nitric Oxide; Nitrites; Nitrogen Oxides; Oxygen; Peroxynitrous Acid; Protein Binding; Reactive Nitrogen Species; Spermine; Xanthine; Xanthine Oxidase | 2004 |
Peroxynitrite formation from the simultaneous reduction of nitrite and oxygen by xanthine oxidase.
Topics: Animals; Cattle; Enzyme Inhibitors; Milk; Nitric Oxide; Nitrites; Onium Compounds; Oxidation-Reduction; Oxygen; Peroxynitrous Acid; Rhodamines; Superoxide Dismutase; Uric Acid; Xanthine Oxidase | 2004 |
Characterization of antioxidant and antiglycation properties and isolation of active ingredients from traditional chinese medicines.
Topics: Antioxidants; Ascorbic Acid; Benzothiazoles; Chromatography, High Pressure Liquid; Clusiaceae; DNA Damage; Dose-Response Relationship, Drug; Hypochlorous Acid; Lipid Peroxidation; Lipids; Mass Spectrometry; Medicine, Chinese Traditional; Models, Chemical; Nitrogen; Peroxynitrous Acid; Phenol; Phospholipids; Sulfonic Acids; Superoxides; Tyrosine; Xanthine Oxidase; Xanthones | 2004 |
Endothelium-leukocyte interactions under the influence of the superoxide-nitrogen monoxide system.
Topics: Antigens, CD; Cell Adhesion; Cells, Cultured; Endothelial Cells; Endothelium, Vascular; Extracellular Matrix; Humans; Integrins; Neutrophils; Nitric Oxide Donors; Peroxynitrous Acid; Reactive Nitrogen Species; Reactive Oxygen Species; Selectins; Xanthine Oxidase | 2004 |
Effects of reactive oxygen and nitrogen species on cyclooxygenase-1 and -2 activities.
Topics: Animals; Catalase; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Female; Hydrogen Peroxide; Hydroxyl Radical; Male; Nitric Oxide; Peroxynitrous Acid; Placenta; Pregnancy; Prostaglandin-Endoperoxide Synthases; Reactive Nitrogen Species; Reactive Oxygen Species; Seminal Vesicles; Sheep; Superoxides; Triazenes; Xanthine; Xanthine Oxidase | 2004 |
The role of peroxynitrite in chemical preconditioning with 3-nitropropionic acid in rat hearts.
Topics: Animals; Biomarkers; Ischemic Preconditioning, Myocardial; L-Lactate Dehydrogenase; Male; Myocardial Reperfusion Injury; Myocardium; NADPH Oxidases; Nitric Oxide; Nitric Oxide Synthase; Nitro Compounds; Peroxynitrous Acid; Propionates; Rats; Rats, Wistar; Succinate Dehydrogenase; Superoxide Dismutase; Tyrosine; Xanthine Oxidase | 2006 |
The effects of chronic exposure to ethanol and cigarette smoke on the formation of peroxynitrite, level of nitric oxide, xanthine oxidase and myeloperoxidase activities in rat kidney.
Topics: Animals; Epithelial Cells; Ethanol; Immunohistochemistry; Inhalation Exposure; Kidney; Kidney Glomerulus; Kidney Tubules, Proximal; Leukocytes, Mononuclear; Male; Nitric Oxide; Peroxidase; Peroxynitrous Acid; Rats; Rats, Wistar; Smoking; Tyrosine; Xanthine Oxidase | 2006 |
The activity of an extract and fraction of Agrimonia eupatoria L. against reactive species.
Topics: Agrimonia; Flavonoids; Free Radical Scavengers; Hydrogen Peroxide; Hydroxyl Radical; Hypochlorous Acid; Peroxynitrous Acid; Plant Extracts; Reactive Oxygen Species; Superoxides; Xanthine Oxidase | 2007 |
Involvement of peroxynitrite in pollen-induced nasal blockage in guinea pigs.
Topics: Administration, Intranasal; Allergens; Allopurinol; Analysis of Variance; Animals; Antioxidants; Azoles; Cryptomeria; Disease Models, Animal; Guinea Pigs; Isoindoles; Leukotriene D4; Male; Nasal Obstruction; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Organoselenium Compounds; Peroxynitrous Acid; Pollen; Rhinitis, Allergic, Seasonal; Xanthine Oxidase | 2008 |
Role of TNF-alpha-induced reactive oxygen species in endothelial dysfunction during reperfusion injury.
Topics: Animals; Antibodies; Coronary Circulation; Coronary Vessels; Disease Models, Animal; Endothelium, Vascular; Female; Male; Mice; Microcirculation; Muscle, Smooth, Vascular; Myocardial Reperfusion Injury; NADPH Oxidases; Neutropenia; Nitric Oxide; Oxidative Stress; Peroxidase; Peroxynitrous Acid; Reactive Oxygen Species; RNA, Messenger; Superoxides; Tumor Necrosis Factor-alpha; Vasodilation; Xanthine Oxidase | 2008 |
Conversion of biliverdin to bilirubin by biliverdin reductase contributes to endothelial cell protection by heme oxygenase-1-evidence for direct and indirect antioxidant actions of bilirubin.
Topics: Angiotensin II; Antioxidants; Bilirubin; Biliverdine; Cytoprotection; Endothelial Cells; Free Radical Scavengers; Gene Knockdown Techniques; Gene Silencing; Heme Oxygenase-1; Humans; Leukocytes; Lipopolysaccharides; Mitochondria; Models, Biological; Neutrophils; Nitrosation; Oxidoreductases Acting on CH-CH Group Donors; Peroxynitrous Acid; Reactive Oxygen Species; Respiratory Burst; Tyrosine; Umbilical Veins; Xanthine Oxidase | 2010 |
Differential effects of NADPH oxidase and xanthine oxidase inhibition on sympathetic reinnervation in postinfarct rat hearts.
Topics: Acetophenones; Allopurinol; Animals; Arrhythmias, Cardiac; Coronary Vessels; Ethidium; Male; Molsidomine; Myocardial Infarction; Myocardium; NADPH Oxidases; Nerve Growth Factor; Oxidative Stress; Peroxynitrous Acid; Rats; Rats, Wistar; Superoxides; Sympathetic Nervous System; Tyrosine; Xanthine Oxidase | 2011 |
Superoxide dictates the mode of U937 cell ascorbic acid uptake and prevents the enhancing effects of the vitamin to otherwise nontoxic levels of reactive oxygen/nitrogen species.
Topics: Ascorbate Oxidase; Ascorbic Acid; bcl-2-Associated X Protein; Cell Line; Dehydroascorbic Acid; Humans; Hydrogen Peroxide; Membrane Potential, Mitochondrial; Peroxynitrous Acid; Reactive Oxygen Species; Superoxides; tert-Butylhydroperoxide; Xanthine Oxidase | 2013 |
Peroxynitrite mediates testosterone-induced vasodilation of microvascular resistance vessels.
Topics: Androgens; Animals; Blotting, Western; Cyclic GMP; Electron Spin Resonance Spectroscopy; In Vitro Techniques; Male; Microvessels; Nitric Oxide; Peroxynitrous Acid; Rats; Rats, Sprague-Dawley; Superoxides; Testosterone; Vascular Resistance; Vasodilation; Xanthine Oxidase | 2013 |
Construction of a biomimetic peroxynitrite-generating platform: a two-component system to synthesize peroxynitrite in situ under the control of light.
Topics: Biomimetic Materials; Gels; Hydrogen-Ion Concentration; Light; Manganese; Nitric Oxide; Oxidation-Reduction; Peroxynitrous Acid; Spectrometry, Fluorescence; Superoxides; Ultraviolet Rays; Xanthine Oxidase | 2013 |
[Biochemical mechanisms of the cardioprotective effect of the K(ATP) channels opener flocalin (medicinal form) in ischemia-reperfusion of myocardium].
Topics: Animals; Apoptosis; Arginase; Cardiotonic Agents; Dogs; Heart; Heme Oxygenase (Decyclizing); Hydroxyl Radical; Lipoxygenase; Mitochondria; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Myocardial Reperfusion Injury; Nitric Oxide; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Peroxynitrous Acid; Pinacidil; Tablets; Xanthine Oxidase | 2013 |
Nitrite attenuated peroxynitrite and hypochlorite generation in activated neutrophils.
Topics: Cells, Cultured; Humans; Hydrogen Peroxide; Hypochlorous Acid; Lipopolysaccharides; NADPH Oxidases; Neutrophils; Nitric Oxide Synthase Type II; Nitrites; Peroxynitrous Acid; Xanthine Oxidase | 2016 |
Inhibition of Oxidative Stress in Renal Ischemia-Reperfusion Injury.
Topics: Allopurinol; Animals; Antioxidants; Apoptosis; Blood Urea Nitrogen; Creatinine; Cytoprotection; Disease Models, Animal; Enzyme Inhibitors; Kidney; Kidney Diseases; Lipid Peroxidation; Male; Metalloporphyrins; Monocytes; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Oxidative Stress; Peroxynitrous Acid; Rats, Sprague-Dawley; Reperfusion Injury; Superoxides; Xanthine Oxidase | 2017 |