Page last updated: 2024-09-03

peroxynitrous acid and 7-nitroindazole

peroxynitrous acid has been researched along with 7-nitroindazole in 8 studies

Compound Research Comparison

Studies
(peroxynitrous acid)
Trials
(peroxynitrous acid)
Recent Studies (post-2010)
(peroxynitrous acid)
Studies
(7-nitroindazole)
Trials
(7-nitroindazole)
Recent Studies (post-2010) (7-nitroindazole)
3,303211,2309151182

Protein Interaction Comparison

ProteinTaxonomyperoxynitrous acid (IC50)7-nitroindazole (IC50)
AromataseHomo sapiens (human)0.7
Amine oxidase [flavin-containing] A Rattus norvegicus (Norway rat)0.71
Nitric oxide synthase, endothelialHomo sapiens (human)2.195
Nitric oxide synthase, brainHomo sapiens (human)2.0267
Nitric oxide synthase, brain Rattus norvegicus (Norway rat)1.1733
Nitric oxide synthase, inducibleHomo sapiens (human)5.8
Nitric oxide synthase, endothelial Rattus norvegicus (Norway rat)0.7

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's7 (87.50)29.6817
2010's1 (12.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ali, SF; Imam, SZ; Islam, F; Itzhak, Y; Slikker, W1
Favre, J; Laude, K; Richard, V; Thuillez, C1
Ali, SF; Appel, SH; Dong, Z; He, Y; Imam, SZ; Jankovic, J; Le, W1
Auker, CR; Chavko, M; McCarron, RM1
Ali, SF; Imam, SZ; Itzhak, Y1
Klassen, SS; Rabkin, SW1
Bravo-San Pedro, JM; Fuentes, JM; González-Polo, RA; Morán, JM; Niso-Santano, M; Ortiz-Ortiz, MA; Soler, G1
Chandramohan, N; Ljunggren-Rose, A; Sriram, S; Whetsell, WO; Yao, SY1

Other Studies

8 other study(ies) available for peroxynitrous acid and 7-nitroindazole

ArticleYear
Prevention of dopaminergic neurotoxicity by targeting nitric oxide and peroxynitrite: implications for the prevention of methamphetamine-induced neurotoxic damage.
    Annals of the New York Academy of Sciences, 2000, Volume: 914

    Topics: 3,4-Dihydroxyphenylacetic Acid; Analysis of Variance; Animals; Chromatography, High Pressure Liquid; Corpus Striatum; Cyclic N-Oxides; Disease Models, Animal; Dopamine; Dopamine Uptake Inhibitors; Drug Administration Schedule; Drug Interactions; Electrochemistry; Free Radical Scavengers; Homovanillic Acid; Imidazoles; Indazoles; Male; Methamphetamine; Mice; Mice, Inbred C57BL; Models, Biological; Neuroprotective Agents; Neurotoxicity Syndromes; Nitric Oxide; Peroxynitrous Acid; Tyrosine

2000
NO produced by endothelial NO synthase is a mediator of delayed preconditioning-induced endothelial protection.
    American journal of physiology. Heart and circulatory physiology, 2003, Volume: 284, Issue:6

    Topics: Acetylcholine; Animals; Blood Pressure; Blood Vessels; Coronary Vessels; Endothelium, Vascular; Free Radical Scavengers; Heart Rate; In Vitro Techniques; Indazoles; Ischemic Preconditioning, Myocardial; Male; Muscle Relaxation; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Nitroprusside; Peroxynitrous Acid; Rats; Rats, Wistar; Selenomethionine; Vasodilator Agents

2003
Role of nitric oxide in rotenone-induced nigro-striatal injury.
    Journal of neurochemistry, 2003, Volume: 86, Issue:6

    Topics: Animals; Brain Chemistry; Cell Count; Cerebral Cortex; Corpus Striatum; Dopamine; Drug Administration Schedule; Enzyme Inhibitors; Female; Indazoles; Insecticides; NADPH Dehydrogenase; Nerve Degeneration; Neurons; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Peroxynitrous Acid; Rats; Rats, Sprague-Dawley; Rotenone; Signal Transduction; Substantia Nigra; Time; Tyrosine 3-Monooxygenase; Uncoupling Agents

2003
Relationship between protein nitration and oxidation and development of hyperoxic seizures.
    Nitric oxide : biology and chemistry, 2003, Volume: 9, Issue:1

    Topics: Animals; Brain; Brain Chemistry; Electroencephalography; Enzyme Inhibitors; Hyperbaric Oxygenation; Indazoles; Male; Nitric Oxide; Nitric Oxide Synthase; Oxidation-Reduction; Oxygen; Peroxynitrous Acid; Proteins; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Seizures; Superoxide Dismutase; Time Factors; Tyrosine

2003
Role of peroxynitrite in methamphetamine-induced dopaminergic neurodegeneration and neuroprotection by antioxidants and selective NOS inhibitors.
    Annals of the New York Academy of Sciences, 2005, Volume: 1053

    Topics: Animals; Antioxidants; Dopamine Uptake Inhibitors; Enzyme Inhibitors; Indazoles; Methamphetamine; Mice; Mice, Knockout; Neurodegenerative Diseases; Neuroprotective Agents; Nitric Oxide Donors; Nitric Oxide Synthase Type I; Peroxynitrous Acid

2005
Palmitate-induced NO production has a dual action to reduce cell death through NO and accentuate cell death through peroxynitrite formation.
    Prostaglandins, leukotrienes, and essential fatty acids, 2008, Volume: 78, Issue:2

    Topics: Animals; Cell Death; Cells, Cultured; Chick Embryo; Cytochromes c; Deoxyglucose; Enzyme Inhibitors; Indazoles; Isoenzymes; Membrane Potentials; Metalloporphyrins; Mitochondria; Myocytes, Cardiac; Nitric Oxide; Nitric Oxide Synthase; Palmitates; Peroxynitrous Acid; Potassium Cyanide

2008
Nitric oxide-mediated toxicity in paraquat-exposed SH-SY5Y cells: a protective role of 7-nitroindazole.
    Neurotoxicity research, 2009, Volume: 16, Issue:2

    Topics: Apoptosis Regulatory Proteins; Cell Cycle Proteins; Cell Death; Cell Line, Tumor; DNA Damage; Dose-Response Relationship, Drug; Drug Interactions; Egtazic Acid; Enzyme Inhibitors; Flow Cytometry; Gene Expression Regulation, Neoplastic; Herbicides; Humans; Indazoles; NADPH Dehydrogenase; Neuroblastoma; Neuroprotective Agents; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Nuclear Proteins; Paraquat; Peroxynitrous Acid; Tetrazolium Salts; Thiazoles; Tumor Suppressor Protein p53

2009
In vitro and in vivo induction and activation of nNOS by LPS in oligodendrocytes.
    Journal of neuroimmunology, 2010, Dec-15, Volume: 229, Issue:1-2

    Topics: 2',3'-Cyclic-Nucleotide Phosphodiesterases; Analysis of Variance; Animals; Animals, Newborn; Arginine; Basic Helix-Loop-Helix Transcription Factors; Brain; Cell Survival; Cells, Cultured; Citrulline; Corpus Callosum; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Indazoles; Lipopolysaccharides; Nerve Tissue Proteins; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; O Antigens; Oligodendroglia; Peroxynitrous Acid; Rats; Rats, Sprague-Dawley; Stem Cells; Tritium

2010