peroxynitric acid has been researched along with nitrates in 1329 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (0.08) | 18.7374 |
| 1990's | 898 (67.57) | 18.2507 |
| 2000's | 420 (31.60) | 29.6817 |
| 2010's | 5 (0.38) | 24.3611 |
| 2020's | 5 (0.38) | 2.80 |
| Authors | Studies |
|---|---|
| Blake, DR; Boaro, M; Candy, TE; Jones, P; Nazhat, NB; Saadalla-Nazhat, RA; Wilkin, HE; Yang, G | 1 |
| Beckman, JS; Ischiropoulos, H; Zhu, L | 1 |
| Farhood, A; Jaeschke, H; Schini, VB | 1 |
| Beckman, JS; Chen, J; Ischiropoulos, H; Martin, JC; Smith, CD; Tsai, M; Zhu, L | 1 |
| Beckman, JS; Chen, J; Harrison, J; Ischiropoulos, H; Martin, JC; Smith, C; Tsai, M; van der Woerd, M; Zhu, L | 1 |
| Beckman, JS; Gunn, C; Zhu, L | 1 |
| Beckman, JS; Carson, M; Chen, J; Ischiropoulos, H; Smith, CD; van der Woerd, M | 1 |
| Bauer, ML; Beckman, JS; Bridges, RJ; Fuller, CM; Matalon, S | 1 |
| Beckman, JS; Bush, KM; Freeman, BA; Radi, R | 1 |
| Bors, W; Michel, C; Saran, M | 1 |
| Carter, WP; Harris, GW; Pitts, JN; Tuazon, EC; Winer, AM | 1 |
| Guo, JL; Hasegawa, T; Katsura, M; Kuriyama, K; Ohkuma, S | 2 |
| Grisham, MB | 1 |
| Amirkhanian, JD; Davis, JM; Horowitz, S; Merritt, TA; Morin, FC; Robbins, CG; Sahgal, N | 1 |
| Ferro, TJ; Higgins, PJ; Johnson, A; Parker, DM; Phelps, DT; Shankar, R | 1 |
| Pryor, WA; Salgo, MG; Squadrito, GL | 1 |
| Alvarez, B; Denicola, A; Radi, R | 1 |
| Lamarque, D; Whittle, BJ | 3 |
| Ohshima, H; Rubio, J; Yermilov, V | 1 |
| Bockaert, J; Culcasi, M; Gaven, F; Lafon-Cazal, M; Pietri, S | 1 |
| Darley-Usmar, VM; Feelisch, M; Goodwin, DA; Moncada, S; Moro, MA; Radomski, MW; Read, NG; Zamora-Pino, R | 1 |
| Durham, SK; Gardner, CR; Goller, NL; Laskin, DL; Laskin, JD; Ohnishi, ST; Quinones, S; Wizemann, TM | 1 |
| Ischiropoulos, H; Salzman, AL; Szabó, C | 2 |
| Deliconstantinos, G; Stavrides, JC; Villiotou, V | 3 |
| Kurata, S; Nakajima, H; Yamashita, U | 1 |
| al-Mehdi, AB; Fisher, AB; Ischiropoulos, H | 1 |
| Dawson, VL | 2 |
| Becchi, M; Friesen, MD; Ohshima, H; Pignatelli, B; Rubio, J; Yermilov, V | 1 |
| Barbeito, L; Beckman, JS; Estévez, AG; Radi, R; Shin, JT; Thompson, JA | 1 |
| Jin, X; Pryor, WA; Squadrito, GL | 2 |
| Bermúdez, E; Pryor, WA; Salgo, MG; Squadrito, GL | 1 |
| Duran, D; Horwitz, J; Ischiropoulos, H | 1 |
| Campbell, G; De Groote, MA; Fang, FC; Granger, D; Prince, R; Xu, Y | 1 |
| Darley-Usmar, V; Moore, KP; Morrow, J; Roberts, LJ | 2 |
| Grimminger, F; Seeger, W; Spriestersbach, R; Walmrath, D; Weissmann, N | 1 |
| Klatt, P; Koesling, D; Mayer, B; Schmidt, K; Schrammel, A | 1 |
| Althaus, JS; Fici, GJ; VonVoigtlander, PF | 2 |
| Lin, KT; Nomen, M; Spur, B; Wong, PY; Xue, JY | 1 |
| Beckman, JS; Crow, JP | 4 |
| Augusto, O; Denicola, A; Gatti, RM; Radi, R; Souza, JM | 1 |
| Ankarcrona, M; Bonfoco, E; Krainc, D; Lipton, SA; Nicotera, P | 1 |
| Lemercier, JN; Pryor, WA; Squadrito, GL | 1 |
| Hasegawa, T; Katsura, M; Kuriyama, K; Narihara, H; Ohkuma, S | 1 |
| Carlo, WA; Cifuentes, J; Matalon, S; Myles, C; Nieves, B; Ruiz-Oronoz, J | 1 |
| Inoue, S; Kawanishi, S | 1 |
| Cross, CE; Eiserich, JP; Halliwell, B; Van der Vliet, A | 2 |
| Beckman, JS; Kelly, DR; Kooy, NW; Royall, JA; Ye, YZ | 1 |
| Beckman, JS; Kooy, NW; Royall, JA | 1 |
| Bolaños, JP; Clark, JB; Heales, SJ; Land, JM | 1 |
| Pryor, WA; Squadrito, GL | 4 |
| Salzman, AL; Szabó, C | 2 |
| al-Mehdi, AB; Ischiropoulos, H | 1 |
| Beckman, JS; Brock, TA; Gore, JZ; Ischiropoulos, H; Tarpey, MM | 1 |
| Freeman, BA; Gutierrez, H; Rubbo, H | 1 |
| Battista, JR; Pryor, WA; Salgo, MG; Squadrito, GL; Stone, K | 1 |
| Gladwell, T; Nguyen, SY; Pou, S; Rosen, GM | 1 |
| Hotchkiss, JH; Liu, RH | 1 |
| Ahmed, N; Daniel, LN; Gannett, P; Liu, K; Mao, Y; Rojanasakul, Y; Saffiotti, U; Shi, X | 1 |
| Van der Walt, BJ; Van Zyl, JM | 1 |
| Darley-Usmar, VM; Moncada, S; Radomski, MW; Salas, E; Villa, LM | 1 |
| Beckman, JS | 3 |
| Beckman, JS; Brunelli, L; Crow, JP | 1 |
| Lipton, SA; Singel, DJ; Stamler, JS | 1 |
| Beckman, JS; Chen, J; Crow, JP; Ye, YZ | 1 |
| Barnard, M; Turrens, JF; Watts, BP | 1 |
| Beckman, JS; Crow, JP; McCord, JM | 1 |
| Cueto, R; Jin, X; Koppenol, WH; Ngu-Schwemlein, M; Pryor, WA; Squadrito, GL; Uppu, PL; Uppu, RM | 1 |
| Bartlett, D; Bounds, PL; Church, DF; Koppenol, WH | 1 |
| Barnes, S; Freeman, BA; Kalyanaraman, B; Kirk, M; Radi, R; Rubbo, H; Telleri, R; Trujillo, M | 1 |
| Beckman, J; Crow, JP; Haddad, IY; Hu, P; Matalon, S; Ye, Y | 1 |
| Hogg, N; Joseph, J; Kalyanaraman, B | 1 |
| Cross, CE; Darley-Usmar, V; Halliwell, B; Kaur, H; O'Neill, CA; Smith, D; Van der Vliet, A | 1 |
| Lenhart, A; Mao, Y; Shi, X | 1 |
| Fridovich, I; Hausladen, A | 1 |
| Castro, L; Radi, R; Rodriguez, M | 1 |
| Bechara, EJ; Briviba, K; Di Mascio, P; Medeiros, MH; Sies, H | 2 |
| Beckman, JS; Galliani, C; Haddad, IY; Hu, P; Matalon, S; Pataki, G | 1 |
| Beckman, JS; Ischiropoulos, H; Kooy, NW; Royall, JA | 1 |
| Althaus, JS; Fici, GJ; Oien, TT; Scherch, HM; Sethy, VH; VonVoigtlander, PF | 1 |
| Beckman, JS; Chen, J; Crow, JP; Ischiropoulos, H | 1 |
| Beckman, JS; Hu, P; Ischiropoulos, H; Matalon, S | 2 |
| Brüne, B; Mohr, S; Stamler, JS | 1 |
| Augusto, O; Gatti, RM; Radi, R | 2 |
| Klatt, P; Mayer, B; Schmidt, K | 1 |
| Beckman, JS; Chen, J; Crow, JP; Gunn, C; Ischiropoulos, H; Koppenol, WH; Radi, R; Smith, CD; Spruell, C; Tsai, M | 1 |
| Antonini, JM; Reasor, MJ; Van Dyke, K; Wu, L; Ye, Z | 1 |
| Beckman, JS; Garver, RI; Haddad, IY; Matalon, S | 1 |
| Boveris, A; Carreras, MC; Catz, SD; Pargament, GA; Poderoso, JJ | 1 |
| Beckman, JS; Ku, DD; Liu, S | 1 |
| Darley-Usmar, V; Gutteridge, JM; Swain, JA | 1 |
| Kooy, NW; Royall, JA | 1 |
| Murphy, MP; Packer, MA | 2 |
| Fayngersh, RP; Hintze, TH; Kaminski, PM; Pritchard, KA; Wolin, MS; Wu, M | 1 |
| Karmeli, F; Loscalzo, J; Mullins, ME; Podolsky, DK; Rachmilewitz, D; Singel, DJ; Stamler, JS; Xavier, RJ | 1 |
| Baker, JR; Beckman, JS; Haddad, IY; Holm, BA; Ischiropoulos, H; Matalon, S | 1 |
| Bradley, WA; Briscoe, P; Brock, TA; Chang, LY; Crapo, J; Freeman, BA; Gianturco, SH; Gore, J; Ku, D; White, CR | 1 |
| Castro, L; Radi, R; Rodriguez, M; Telleri, R | 1 |
| Denicola, A; Radi, R; Rubbo, H | 1 |
| Cross, CE; Halliwell, B; Kaur, H; O'Neill, CA; van der Vliet, A | 1 |
| Denicola, A; Radi, R; Rodríguez, D; Rubbo, H | 1 |
| Beckman, JS; Carson, M; Koppenol, WH; Smith, CD | 1 |
| Darley-Usmar, VM; Graham, A; Hogg, N; Moncada, S | 1 |
| Darley-Usmar, V; Graham, A; Hogg, N; Kalyanaraman, B; Moncada, S; O'Leary, V | 1 |
| Beckman, JS; Cosgrove, TP; Freeman, BA; Radi, R | 1 |
| Anderson, VE; Brenowitz, M; Jamison, E; King, PA; Strahs, D | 1 |
| Chen, HS; Choi, YB; Lei, SZ; Lipton, SA; Loscalzo, J; Pan, ZH; Singel, DJ; Stamler, JS; Sucher, NJ | 1 |
| Floris, R; Jones, P; Piersma, SR; Wever, R; Yang, G | 1 |
| Huie, RE; Padmaja, S | 1 |
| Pryor, WA; Stone, K | 1 |
| Guérin, MC; Salman-Tabcheh, S; Torreilles, J | 1 |
| Clark, DA; Miller, MJ; Seago, ND | 1 |
| Marx, J | 1 |
| Dikalov, S; Grigor'ev, I; Kirilyuk, I | 1 |
| Halliwell, B; Tritschler, H; Whiteman, M | 1 |
| Bouton, C; Drapier, JC; Raveau, M | 1 |
| Juedes, MJ; Wogan, GN | 1 |
| Miesel, R; Murphy, MP; Packer, MA | 1 |
| Ghio, AJ; Oury, TD; Piantadosi, CA; Tatro, L | 1 |
| Carreras, MC; Catz, SD; Poderoso, JJ | 1 |
| O'Connor, M; Salzman, AL; Szabó, C; Wong, H; Zingarelli, B | 1 |
| Bigelow, DJ; Ferrington, DA; Hühmer, AF; Schöneich, C; Viner, RI | 1 |
| Richter, C; Schweizer, M | 1 |
| Ullrich, V; Zou, MH | 1 |
| Derossi, D; Greene, LA; Prochiantz, A; Shelanski, ML; Troy, CM | 1 |
| Augusto, O; Junqueira, VB; Santos, AM; Vásquez-Vivar, J | 1 |
| Darley-Usmar, V; Knowles, RG; Lizasoain, I; Moncada, S; Moro, MA | 1 |
| Pryor, WA; Squadrito, GL; Uppu, RM | 1 |
| Chock, PB; Kong, SK; Stadtman, ER; Yim, MB | 1 |
| Danbolt, NC; Gjesdal, O; Levy, LM; Racagni, G; Rossi, D; Trotti, D; Volterra, A | 1 |
| Fréjaville, C; Hogg, N; Kalyanaraman, B; Karoui, H; Tordo, P | 1 |
| Coene, A; Folkerts, G; Henricks, PA; Nijkamp, FP; Sadeghi-Hashjin, G; van Ark, I; van der Linde, HJ; Verheyen, AK | 1 |
| Salzman, AL; Szabó, C; Zingarelli, B | 2 |
| Piantadosi, CA; Stamler, JS | 1 |
| Darley-Usmar, VM; Knowles, RG; Lizasoain, I; Moncada, S; Moro, MA; Radomski, MW; Su, Y | 1 |
| Blake, DR; Frears, ER; O'Connell, JP; Winyard, PG; Zhang, Z | 1 |
| Day, BJ; Salzman, AL; Szabó, C | 1 |
| Duran, D; Gow, AJ; Ischiropoulos, H; Malcolm, S | 1 |
| Cassina, A; Radi, R | 1 |
| Cook, J; Ford, PC; Grisham, MB; Hanbauer, I; Krishna, M; Laval, F; Laval, J; Liebmann, J; Mitchell, JB; Nims, RW; Pacelli, R; Wink, DA | 1 |
| Hogg, N; Joseph, J; Kalyanaraman, B; Karoui, H | 1 |
| Laskey, RE; Mathews, WR | 1 |
| Briviba, K; Masumoto, H; Roussyn, I; Sies, H | 1 |
| Constantine-Paton, M; Rentería, RC | 1 |
| Hurst, JK; Jiang, Q; Lymar, SV | 1 |
| Shi, X; Zang, LY | 1 |
| Buttery, LD; Chester, AH; Evans, TJ; Parums, DV; Polak, JM; Springall, DR; Standfield, EN; Yacoub, MH | 1 |
| Dawson, TM; Dawson, VL; Snyder, SH; Xia, Y; Zweier, JL | 1 |
| Halliwell, B; Kaur, H; Whiteman, M | 2 |
| O'Connor, M; Salzman, AL; Szabó, C; Zingarelli, B | 1 |
| Berlett, BS; Chock, PB; Friguet, B; Stadtman, ER; Yim, MB | 1 |
| Fukuyama, N; Ichimori, K; Ishida, H; Nakazawa, H; Su, Z | 1 |
| Anderson, VE; Ehresmann, B; Ehresmann, C; Götte, M; Gross, HJ; Heumann, H; Isel, C; Keith, G; Marquet, R | 1 |
| Fukahori, M; Hirota, Y; Ichimori, K; Ishida, H; Nakazawa, H | 1 |
| Al-Mehdi, A; Duran, D; Ischiropoulos, H; Nelson, J | 1 |
| Katusic, ZS | 1 |
| Pryor, WA; Uppu, RM | 3 |
| Bigelow, DJ; Hühmer, AF; Schöneich, C; Viner, RI | 1 |
| Cadet, J; Douki, T | 1 |
| Barker, JE; Bolaños, JP; Cassidy, A; Clark, JB; Heales, SJ; Land, JM | 1 |
| Lai, PS; Rodriguez, A; Spur, BW; Wong, PY; Yin, K | 1 |
| Balish, E; Jones-Carson, J; Vazquez-Torres, A | 1 |
| Vatassery, GT | 1 |
| Dickens, BF; Komarov, AM; Mak, IT; Stafford, RE; Wagner, TL; Weglicki, WB | 1 |
| Elliott, SJ | 1 |
| Guo, JL; Hasegawa, T; Katsura, M; Kuriyama, K; Narihara, H; Ohkuma, S | 1 |
| Bolaños, JP; Medina, JM | 1 |
| Koppenol, WH; Padmaja, S; Ramezanian, MS | 1 |
| Beckman, JS; Rosen, H; Sampson, JB | 1 |
| Cueto, R; Pryor, WA; Squadrito, GL; Uppu, RM | 2 |
| Beckman, JS; Kissner, R; Koppenol, WH | 2 |
| Bohle, DS; Glassbrenner, PA; Hansert, B | 1 |
| Beckman, JS; Hamilton, TP; Tsai, HH | 1 |
| Augusto, O; Gatti, RM; Radi, R; Vásquez-Vivar, J | 1 |
| Radi, R | 2 |
| Jin, X; Pryor, WA; Squadrito, GL; Uppu, RM | 1 |
| Darley-Usmar, VM; Patel, RP | 1 |
| Brockman, DE; Eis, AL; Greer, I; Lyall, F; Myatt, L; Rosenfield, RB | 1 |
| Duran, D; Gow, A; Ischiropoulos, H; Thom, SR | 1 |
| Denicola, A; Freeman, BA; Radi, R; Trujillo, M | 1 |
| Alvarez, MN; Castro, L; Radi, R | 1 |
| Pryor, WA; Salgo, MG | 1 |
| Chou, SM; Komai, K; Wang, HS | 1 |
| Bourdon, DM; Currie, MG; Manning, PT; Salvemini, D; Stern, MK; Wang, ZQ | 1 |
| Althaus, JS; Fici, GJ; Hall, ED; Von Voigtlander, PF | 1 |
| Bouwens, L; Delaney, CA; Eizirik, DL; Hellman, B; Tyrberg, B; Vaghef, H | 1 |
| Kawka, DW; Mumford, RA; Riehl, TE; Scott, S; Singer, II; Stenson, WF; Weidner, JR | 1 |
| Behar-Cohen, FF; Courtois, Y; Droy-Lefaix, MT; Faure, V; Goureau, O; Heydolph, S | 1 |
| Murphy, MP; Packer, MA; Porteous, CM; Scarlett, JL | 1 |
| Deliconstantinos, G; Villiotou, V | 1 |
| Kooy, NW; Lewis, SJ | 3 |
| Lipton, SA | 1 |
| Alvarez, B; Barnes, S; Freeman, BA; Kirk, M; Radi, R; Rubbo, H | 1 |
| de Montellano, PR; Gerber, NC; Hühmer, AF; Schöneich, C | 1 |
| Bhattacharya, M; Fiala, ES; Li, H; Sodum, RS | 1 |
| Beckman, JS; Kontos, HA; Wei, EP | 1 |
| Cueto, R; Lemercier, JN; Padmaja, S; Pryor, WA; Squadrito, GL | 2 |
| Cueto, R; Pryor, WA; Salgo, MG; Squadrito, GL; Uppu, RM | 1 |
| Szabó, C | 7 |
| Kurata, S; Matsumoto, M; Yamashita, U | 1 |
| Niknahad, H; O'Brien, PJ | 1 |
| Briviba, K; Roussyn, I; Sharov, VS; Sies, H | 1 |
| Beckman, JS; Crow, JP; Kerby, JD; MacMillan-Crow, LA; Thompson, JA | 1 |
| Knowles, RG | 2 |
| Halliwell, B; Whiteman, M | 4 |
| Bruckdorfer, KR; Diplock, AT; Leake, D; Rice-Evans, C | 1 |
| Clark, DA; Eloby-Childress, S; Liu, X; Miller, MJ; Olister, S; Pierce, MR; Rivera, D; Thompson, JH; Voelker, CA; Zhang, XJ | 1 |
| Masumoto, H; Sies, H | 1 |
| Bartosz, G; Soszyński, M | 4 |
| Murphy, MP; Packer, MA; Porteous, CM | 1 |
| Wang, P; Zweier, JL | 1 |
| Deliconstantinos, G; Dimopoulos, C; Mitropoulos, D; Stavrides, J; Villiotou, V; Zervas, A | 1 |
| Barbeito, L; Beckman, JS; MacMillan-Crow, LA; Shin, JT; Thompson, JA | 1 |
| Felix, CC; Kalyanaraman, B; Karoui, H; Singh, RJ | 1 |
| Wolin, MS; Xie, YW | 1 |
| Balazy, M; Barton, A; Bednar, MM; Bingham, J; Booth, C; Fuller, SP; Golding, L; Gross, CE; Murphy, M | 1 |
| Ballmaier, D; Briviba, K; Epe, B; Roussyn, I; Sies, H | 1 |
| Czapski, G; Goldstein, S; Pryor, WA; Squadrito, GL | 1 |
| Barker, JE; Bolaños, JP; Clark, JB; Heales, SJ; Land, JM | 1 |
| Beckman, JS; Koppenol, WH | 1 |
| Akaike, A; Kawamura, T; Kimura, J; Kitamura, Y; Sawada, H; Shimohama, S; Taniguchi, T | 1 |
| Dallner, G; Ernster, L; Forsmark-Andrée, P; Persson, B; Radi, R | 1 |
| Castro, CE; Wade, RS | 1 |
| Bouchier-Hayes, D; Redmond, HP; Wang, JH | 1 |
| Galis, ZS; Harrison, DG; Meng, XP; Rajagopalan, S; Ramasamy, S | 1 |
| Salzman, AL; Szabó, C; Wong, HR | 1 |
| Kissner, R; Koppenol, WH; Masumoto, H; Sies, H | 1 |
| Darley-Usmar, VM; Diczfalusy, U; Dzeletovic, S; Patel, RP; Wilson, MT | 1 |
| Ohshima, H; Rubio, J; Yermilov, V; Yoshie, Y | 1 |
| Clark, DA; Liu, X; Mannick, EE; Miller, MJ; Sandoval, M; Zhang, XJ | 1 |
| Crews, BC; Landino, LM; Marnett, LJ; Morrow, JD; Timmons, MD | 1 |
| Augusto, O; Capurro, Mde L; de Bianchi, AG; Giorgio, S; Linares, E | 1 |
| Boota, A; Davies, P; Johnson, B; Kim, YM; Pitt, B; Zar, H | 1 |
| Baldwin, J; Francescutti, D; Lee, L; Mutus, B | 1 |
| Pasquet, JP; Ullrich, V; Zou, MH | 1 |
| Bohle, DS; Gorren, AC; Hansert, B; Mayer, B; Pfeiffer, S; Schmidt, K; Werner, ER | 1 |
| Fujimoto, Y; Fujita, T; Nishida, H; Sakamoto, Y; Sakuma, S; Uchiyama, T; Yoshioka, K | 1 |
| Lin, KT; Sun, FF; Wong, PY; Xue, JY | 1 |
| Bassenge, E; Dikalov, S; Skatchkov, M | 2 |
| O'Connor, M; Salzman, AL; Saunders, C; Szabó, C | 1 |
| Minetti, M; Pietraforte, D | 2 |
| Mondoro, TH; Shafer, BC; Vostal, JG | 1 |
| Campbell, B; Grayson, J; Hayward, R; Lefer, AM; Lefer, DJ; Nossuli, T; Salamon, M; Scalia, R | 1 |
| Haussmann, HJ; Muller, T; Schepers, G | 1 |
| Anno, PR; Kim, YM; Murphy, T; Salama, G; Stoyanovsky, D | 1 |
| Cueto, R; Lemercier, JN; Pryor, WA; Squadrito, GL; Uppu, RM; Zhang, H | 1 |
| Cuzzocrea, S; Gilad, E; Salzman, AL; Szabó, C; Zingarelli, B | 1 |
| Aruoma, OI; England, TG; Halliwell, B; Whiteman, M | 1 |
| Augusto, O; Giorgio, S; Linares, E | 1 |
| Schulz, R; Strynadka, KD; Yasmin, W | 1 |
| Alvarez, B; Augusto, O; Gatti, RM; Quijano, C; Radi, R | 1 |
| Ferrer-Sueta, G; Radi, R; Salzman, AL; Southan, GJ; Szabó, C; Zingarelli, B | 1 |
| Clanachan, AS; Dodge, KL; Lopaschuk, GD; Schulz, R | 1 |
| Beckman, JS; Perry, G; Richey Harris, PL; Sayre, LM; Smith, MA | 1 |
| Ames, BN; Blount, BC; Christen, S; Lee, HH; Shigenaga, MK; Shigeno, ET; Yip, H | 1 |
| Ames, BN; Christen, S; Duncan, MW; Shigenaga, MK; Southwell-Keely, PT; Woodall, AA | 1 |
| Bartosz, G | 1 |
| Cook, JA; Grisham, MB; Jourd'heuil, D; Kim, SY; Krishna, MC; Miles, AM; Mitchell, JB; Pacelli, R; Russo, A; Vodovotz, Y; Wink, DA | 1 |
| Anggård, EE; Carrier, MJ; Laight, DW | 1 |
| Caulfield, JL; Dedon, PC; Kennedy, LJ; Moore, K; Tannenbaum, SR | 1 |
| Hoglen, NC; Liebler, DC; Sipes, IG; Waller, SC | 1 |
| Crapo, JD; Day, BJ; Salzman, AL; Szabó, C; Zingarelli, B | 1 |
| Asano, Y; Hiramoto, K; Kikugawa, K; Tomiyama, S | 1 |
| Fukuyama, N; Hida, M; Ichimori, K; Ishida, H; Nakazawa, H; Takebayashi, Y | 1 |
| Hemmens, B; Leopold, E; Mayer, B; Pfeiffer, S; Schmidt, K; Werner, ER | 1 |
| Akaike, T; Bagasra, O; Bobroski, L; Champion, JM; Farber, JL; Hooper, DC; Kean, R; Koprowski, H; Maeda, H; Marini, JC; Ohnishi, ST; Sarker, AB; Zborek, A | 1 |
| Halliwell, B; Pannala, AS; Rice-Evans, CA; Singh, S | 1 |
| Abdalla, DS; Moriel, P | 1 |
| Rabinovitch, A; Suarez-Pinzon, WL; Szabó, C | 1 |
| Fisher, D; Ischiropoulos, H; Kang, M; Thom, SR | 1 |
| Demiryürek, AT; Kahraman, S | 1 |
| Holm, P; Kankaanranta, H; Knowles, RG; Kosonen, O; Moilanen, E; Vuorinen, P | 1 |
| Barnes, PJ; Giaid, A; Saleh, D | 1 |
| Folkerts, G; Henricks, PA; Muijsers, RB; Nijkamp, FP; Sadeghi-Hashjin, G | 2 |
| Hamazaki, K; Inai, Y; Inoue, M; Utsumi, K; Yabuki, M; Yasuda, T; Yoshioka, T | 1 |
| Hühmer, AF; Nishida, CR; Ortiz de Montellano, PR; Schöneich, C | 1 |
| Barone, FC; Christopher, TA; Feuerstein, GZ; Gao, F; Guo, Y; Liu, GL; Lopez, BL; Ma, XL; Ruffolo, RR; Yue, TL | 1 |
| Aoki, T; Itakura, K; Kato, Y; Kawakishi, S; Osawa, T | 1 |
| Cowman, MK; Li, M; Rosenfeld, L; Vilar, RE | 1 |
| Ferguson, E; Hogg, N; Kalyanaraman, B; Singh, RJ | 1 |
| Hock, CE; Liu, P; Nagele, R; Wong, PY | 1 |
| Chabot, F; Evans, TW; Mitchell, JA; Quinlan, GJ | 1 |
| Batten, J; Corbett, SA; Hughes, SP; Hukkanen, M; Konttinen, YT; Maclouf, J; McCarthy, ID; Polak, JM; Santavirta, S | 1 |
| Van Dyke, K | 1 |
| Ohshima, H; Yoshie, Y | 2 |
| Akaike, T; Ando, M; Ichimori, K; Maeda, H; Miyajima, S; Nagano, T; Okamoto, T; Suga, M | 1 |
| Chandler, RT; Crow, JP; Parks, DA; Skinner, HB; Skinner, KA; Thompson, JA | 1 |
| Beckman, JS; Kelly, DR; Kooy, NW; Lewis, SJ; Royall, JA; Ye, YZ | 1 |
| Rao, NA; Wu, GS; Zhang, J | 1 |
| Xia, Y; Zweier, JL | 1 |
| Lemercier, JN; Pryor, WA; Squadrito, GL; Uppu, RM; Zhang, H | 1 |
| Curtis, JF; Eling, TE; Gierse, JK; Gunther, MR; Hsi, LC; Marnett, LJ; Mason, RP | 1 |
| O'Connor, M; Salzman, AL; Szabó, C | 2 |
| Adachi, K; Kobayashi, K; Kono, Y; Sawa, Y; Shibata, H; Tagawa, S; Ueda, A | 1 |
| Barbeito, L; Beckman, JS; Estévez, AG; Johnson, GV; Spear, N | 1 |
| Harris, SR; Thorgeirsson, UP | 1 |
| Hinton, DR; Hofman, FM; Incardonna, F; van der Veen, RC | 1 |
| Clark, JE; Foresti, R; Green, CJ; Motterlini, R | 1 |
| Asahi, M; Fujii, J; Hori, M; Kuzuya, T; Shimonishi, Y; Takao, T; Taniguchi, N | 1 |
| Cuzzocrea, S; O'Connor, M; Salzman, AL; Szabó, C; Zingarelli, B | 2 |
| Fava, E; Leist, M; Montecucco, C; Nicotera, P | 1 |
| Bouton, C; Drapier, JC; Hirling, H | 1 |
| Bast, A; Haenen, GR; Korthouwer, RE; Paquay, JB | 1 |
| Caputi, AP; Costantino, G; Cuzzocrea, S; Salzman, AL; Szabó, A; Szabó, C; Zingarelli, B | 1 |
| Augusto, O; Denicola, A; Radi, R; Vásquez-Vivar, J | 1 |
| Hurst, JK; Lymar, SV | 2 |
| Gavita, SM; Giaid, A; McDermott, CD; Shennib, H | 1 |
| Bloom, FE; Gruol, DL; Horn, TF; Sorg, O; Yu, N | 1 |
| Goss, SP; Hogg, N; Kalyanaraman, B | 2 |
| Blount, BC; Duncan, MW; Smythe, GA; Yi, D | 1 |
| Berliner, LJ; Clanton, TL; Diaz, PT; Merola, AJ; Narayan, M | 1 |
| Quach, HT; Smith, WE; Ungar, F; Vatassery, GT | 1 |
| Halliwell, B | 1 |
| Davidson, CA; Kaminski, PM; Wolin, MS | 2 |
| Grisham, MB; Jourd'heuil, D; Milligan, SA; Owens, MW | 1 |
| Martin, C; Ullrich, V; Zou, M | 1 |
| Kondo, H; Niki, E; Takahashi, M | 1 |
| Ade, P; Balduzzi, M; Guastadisegni, C; Levi, G; Minghetti, L; Nicolini, A; Polazzi, E | 1 |
| Cueto, R; Lemercier, JN; Padmaja, S; Pryor, WA; Squadrito, GL; Uppu, RM | 1 |
| Alam, ZI; Cairns, N; Daniel, SE; Halliwell, B; Jenner, A; Jenner, P; Lees, AJ; Marsden, CD | 1 |
| Fink, MP; Menconi, MJ; Unno, N | 1 |
| Lin, KT; Wong, PY; Xue, JY | 3 |
| Gilad, E; Salzman, AL; Szabó, C; Zingarelli, B | 1 |
| Ischiropoulos, H; Thom, SR; Xu, YA | 1 |
| Costa, AD; Fagian, MM; Gadelha, FR; Radi, R; Thomson, L; Vercesi, AE | 1 |
| Christie, P; Dinh-Xuan, AT; el Yaagoubi, A; Pinot, F; Polla, BS | 1 |
| Hogg, N; Kalyanaraman, B; Martasek, P; Masters, BS; Pritchard, KA; Vásquez-Vivar, J | 1 |
| Bao, J; Dawson, TM; Dawson, VL; Eliasson, MJ; Hurn, PD; Mandir, AS; Pieper, A; Sampei, K; Snyder, SH; Traystman, RJ; Wang, ZQ | 1 |
| Fu, W; Furukawa, K; Goodman, Y; Luo, H; Mattson, MP | 1 |
| Bauersachs, J; Bouloumié, A; Busse, R; Fleming, I; Linz, W; Schölkens, BA; Wiemer, G | 1 |
| Han, B; Häussinger, D; Klonowski-Stumpe, H; Niederau, C; Sata, N | 1 |
| Hayward, R; Lefer, AM; Nossuli, TO; Scalia, R | 1 |
| Imlay, JA; Keyer, K | 1 |
| Briviba, K; Klotz, LO; Sharov, VS; Sies, H | 1 |
| Bechara, EJ; Briviba, K; Catalani, LH; Di Mascio, P; Medeiros, MH; Sasaki, ST; Sies, H | 1 |
| Beckman, JS; Crow, JP; Sampson, JB; Thompson, JA; Zhuang, Y | 1 |
| Barnes, S; Beckman, JS; Crow, JP; Kirk, M; Strong, M; Ye, YZ | 1 |
| Ischiropoulos, H; Kooy, NW; Royall, JA | 1 |
| Caputi, AP; Cuzzocrea, S; O'Connor, M; Salzman, AL; Szabó, C; Zingarelli, B | 1 |
| Cornwell, T; Darley-Usmar, V; Jo, H; Lincoln, T; Matalon, S; McAndrew, J; Moellering, D; Patel, RP; White, CR | 1 |
| Clark, DA; Liu, X; Mannick, EE; Miller, MJ; Sandoval, M | 1 |
| Wolf, G | 1 |
| Janssen, YM; Matalon, S; Mossman, BT | 1 |
| Evans, PJ; Halliwell, B; Tredger, JM; Whiteman, M | 1 |
| Brain, SD; Greenacre, S; Ridger, V; Wilsoncroft, P | 1 |
| Augustin, W; Keilhoff, G; Noack, H; Possel, H; Wolf, G | 1 |
| Barnes, S; Darley-Usmar, VM; Kirk, M; Moellering, D; Patel, RP; White, CR | 1 |
| Beger, HG; Bruckner, UB; Butzer, U; Han, F; Jung, M; Marzinzig, M; Nussler, AK; Shu, Z | 1 |
| Haddad, IY; Matalon, S; Nieves-Cruz, B | 1 |
| Groves, JT; Hunt, JA; Lee, J | 1 |
| Martin, SW; Murphy, MP; Packer, MA; Scarlett, JL | 2 |
| Cornwell, T; Darley-Usmar, VM; Digerness, S; Jo, H; Lincoln, TM; McAndrew, J; Moellering, D; Patel, R; White, CR | 1 |
| Almeida, A; Bolaños, JP; Clark, JB; Fernández, E; Heales, SJ; Land, JM; Medina, JM | 1 |
| Bruckdorfer, KR; Jacobs, M; Khan, J | 1 |
| Bruckdorfer, KR; Jacobs, M; Khan, J; Naseem, KM | 1 |
| Brown, GC; McBride, AG | 1 |
| Anggård, EE; Carrier, MJ; Quine, LA | 1 |
| Cuzzocrea, S; Gilad, E; Hake, P; Salzman, AL; Szabó, C; Zingarelli, B | 1 |
| Brain, SD; Greenacre, SA; Halliwell, B; Handy, RL; Moore, PK; Ridger, VC; Whiteman, M | 1 |
| Lind, J; Merényi, G | 2 |
| Bugnon, P; Kissner, R; Koppenol, WH; Lye, PG; Nauser, T | 1 |
| Boggs, S; Lapetina, EG; Mohr, S; Scivittaro, V | 1 |
| Groves, JT; Lee, J; Marla, SS | 1 |
| Fujii, H; Hoshiai, K; Ichimori, K; Nakazawa, H | 1 |
| Dowell, FJ; Martin, W | 2 |
| Di Stasi, AM; Mallozzi, C; Minetti, M | 2 |
| Amin, N; Pearce, B | 1 |
| Cross, AH; Manning, PT; Misko, TP; Stern, MK | 1 |
| Albrecht, S; Heinzmann, J; Ockert, D; Oelschläger, S; Schilling, JU; Zimmermann, T | 1 |
| Hediger, MA; Nussberger, S; Trotti, D; Volterra, A | 1 |
| Akaike, T; Maeda, H; Suga, M | 1 |
| Halliwell, B; Rehman, A; Whiteman, M | 1 |
| Bruce-Keller, AJ; Germeyer, A; Holtsberg, FW; Hutchins, JB; Keller, JN; Kindy, MS; Mattson, MP; St Clair, DK; Steiner, SM; Yen, HC | 1 |
| Minetti, M; Scorza, G | 1 |
| Hemmens, B; Mayer, B | 1 |
| Ashida, K; Ataka, M; Kamisaki, Y; Kishimoto, Y; Nakamoto, K; Wada, K; Yamada, Y | 1 |
| Champion, JM; Chaudhry, I; Dickson, GM; Hooper, DC; Kean, RB; Koprowski, H; Spitsin, S | 1 |
| Barbeito, L; Beckman, JS; Estévez, AG; Henderson, CE; Manuel, SM; Radi, R; Spear, N | 1 |
| Pryor, WA; Uppu, RM; Winston, GW | 1 |
| Ferrer-Sueta, G; Radi, R; Ruiz-Ramírez, L | 1 |
| Cuzzocrea, S; Hake, P; Salzman, AL; Szabó, C; Zingarelli, B | 1 |
| Padmaja, S; Pryor, WA; Squadrito, GL | 1 |
| Alvarez, B; Augusto, O; Gatti, RM; Radi, R; Vasquez-Vivar, J | 1 |
| Alayash, AI; Cashon, RE; Ryan, BA | 1 |
| Martínez, JA; Metha, B; Pollet, E; Turrens, JF; Watts, BP | 1 |
| Pryor, WA; Squadrito, GL; Zhang, H | 2 |
| Angaut-Petit, D; Blanchard, B; Ducrocq, C; Faille, L; Meunier, FA; Morot Gaudry-Talarmain, Y; Moulian, N | 1 |
| Ohshima, H; Szabó, C | 1 |
| Czapski, G; Goldstein, S | 2 |
| Brovkovych, S; Brovkovych, V; Huk, I; Kiechle, F; Maliński, T; Patton, S | 1 |
| Quach, HT; Smith, WE; Vatassery, GT | 1 |
| Cookson, MR; Ince, PG; Shaw, PJ | 1 |
| Arnal, JF; Michel, JB; Pueyo, ME; Rami, J | 1 |
| Gow, AJ; Ischiropoulos, H; Thom, SR | 1 |
| Cuthbertson, BH; Galley, HF; Webster, NR | 1 |
| de Jager, A; Heeringa, P; Huitema, MG; Kallenberg, CG; Klok, PA; Moshage, H; Schep, AJ; van Goor, H | 1 |
| Baudier, J; Chambaz, E; Cochet, C; Garin, J; Mély, Y; Ohshima, H; Scotto, C | 1 |
| Christopher, TA; Ischiropoulos, H; Liu, GL; Lopez, BL; Ma, XL | 1 |
| Cheung, PY; Danial, H; Jong, J; Schulz, R | 1 |
| Blanchard, B; Dendane, M; Ducrocq, C; Gallard, JF; Houée-Levin, C; Karim, A; Launay, JM; Payen, D | 1 |
| Clark, DA; Miller, MJ; Muanza, DN; Ronzio, RA; Sandoval, M | 1 |
| Balavoine, GG; Bejan, D; Geletti, YV | 1 |
| Williams, DL | 1 |
| Fukuyama, N; Hoshiai, K; Ishida, H; Nakazawa, H; Shinohara, Y; Takizawa, S | 1 |
| Chiueh, CC; Lin, AM; Rauhala, P | 1 |
| Forman, LJ; Liu, P; Nagele, RG; Wong, PY; Yin, K | 1 |
| De Koster, BM; Elferink, JG; Van Der Zee, J; Vansteveninck, J; Vanuffelen, BE | 1 |
| Currie, MG; Misko, TP; Salvemini, D; Stern, MK; Wang, ZQ | 1 |
| Crow, JP; MacMillan-Crow, LA; Thompson, JA | 1 |
| Hiltunen, TP; Luoma, JS; Marklund, SL; Särkioja, T; Strålin, P; Ylä-Herttuala, S | 1 |
| Hansen, P; Heinecke, JW; Holloszy, JO; Leeuwenburgh, C; Shaish, A | 1 |
| Davidge, ST; McLaughlin, MK; Ojimba, J | 1 |
| Liu, P; Nagele, R; Wong, PY; Yin, K | 1 |
| Denenberg, AG; Kennedy, M; Salzman, AL; Szabó, C | 1 |
| Colgan, SP | 1 |
| Brandi, ML; MacIntyre, I; Mancini, L; Moradi-Bidhendi, N | 1 |
| Berlett, BS; Levine, RL; Stadtman, ER | 1 |
| Kissner, R; Koppenol, WH | 1 |
| Halliwell, B; Jenner, P; Reist, M | 1 |
| Pannala, AS; Rice-Evans, C; Sampson, J; Singh, S | 1 |
| Denicola, A; Radi, R; Souza, JM | 1 |
| Cuzzocrea, S; Hake, P; Kun, E; O'Connor, MP; Salzman, A; Scott, GS; Szabó, C; Virág, L; Zingarelli, B | 1 |
| Comtois, A; el-Dwairi, Q; Guo, Y; Hussain, SN | 1 |
| Ashida, K; Itoh, T; Kamisaki, Y; Kanda, G; Kishimoto, Y; Nakamoto, K; Ohkura, T; Wada, K | 1 |
| Graves, JE; Kooy, NW; Lewis, SJ | 1 |
| Beckman, JS; De Sarno, P; Jope, RS; Li, X; Song, L | 1 |
| Caputi, AP; Cuzzocrea, S; Zingarelli, B | 5 |
| Akiba, Y; Fujimori, H; Higuchi, H; Hirokawa, M; Hokari, R; Ishii, H; Kimura, H; Kurose, I; Miura, S; Serizawa, H; Shigematsu, T; Tsuzuki, Y | 1 |
| Koesling, D; Mayer, B; Pfeiffer, S; Schmidt, K; Schrammel, A | 1 |
| Inoue, M; Kashiba, M; Konaka, R | 1 |
| Cakici, I; Demiryürek, AT; Kanzik, I | 1 |
| Blasig, IE; Davies, KJ; Grune, T; Haseloff, R; Roloff, B; Sitte, N | 1 |
| de Groot, H; Kirsch, M; Lomonosova, EE; Rauen, U | 1 |
| Halliwell, B; Pannala, AS; Razaq, R; Rice-Evans, CA; Singh, S | 1 |
| Cabelli, D; Czapski, G; Goldstein, S; Saha, A | 1 |
| Branka, JE; Dreno, B; Jarry, A; Laboisse, CL; Sainte-Marie, I; Tenaud, I; Vallette, G | 1 |
| Ballard, PL; Ballard, RA; Banks, BA; Ischiropoulos, H; McClelland, M | 1 |
| Kono, Y; Shibata, H; Ueda, A; Yamasaki, T | 1 |
| Brookes, PS; Clark, JB; Heales, SJ; Land, JM | 2 |
| Ischiropoulos, H | 1 |
| Lin, KT; Lin, MC; Spokas, EG; Sun, FF; Wong, PY; Xue, JY | 1 |
| Kaminski, PM; Wolin, MS; Xie, YW | 1 |
| Cooper, CE; Sharpe, MA | 2 |
| Bouchemal-Chibani, N; Carayon, A; Das, BC; Dendane, M; Doan, BT; Ducrocq, C; Gillet, B; Karim, A; Laprévote, O; Payen, D; Serani, L | 1 |
| Ermilov, V; Ishio, Iu; Oshima, Kh | 1 |
| de Groot, H; Kirsch, M; Korth, HG; Lomonosova, EE; Sustmann, R | 1 |
| Davies, MJ; Stocker, R; Thomas, SR | 1 |
| Jeong, JK; Juedes, MJ; Wogan, GN | 1 |
| Mayer, B; Pfeiffer, S; Schmidt, K | 2 |
| Briviba, K; Cotgreave, IA; Engman, L; Klotz, LO; Sies, H; Tamler, R | 1 |
| Di Stasi, AM; Mallozzi, C; Minetti, M; Pietraforte, D | 1 |
| Arai, Y; Cheng, X; Egashira, K; Fukuyama, N; Momii, H; Nakazawa, H; Oyama, Ji; Shimokawa, H; Takeshita, A | 1 |
| Grace, SC; Pryor, WA; Salgo, MG | 1 |
| Maruyama, W; Naoi, M; Takahashi, T | 1 |
| Arnaud, S; Ben-Ari, Y; Cachin, N; Charriaut-Marlangue, C; Coeroli, L; Plotkine, D; Plotkine, M; Renolleau, S | 1 |
| Inoue, M; Kashiba, M; Nagata, K; Nakamura, A; Nishikawa, M; Sato, EF; Tamura, T; Yu, H | 1 |
| Fujimura, T; Murayama, K; Taka, H; Yamakura, F | 1 |
| Hogg, N; Kalyanaraman, B; Konorev, EA | 1 |
| DuVall, MD; Fuller, CM; Matalon, S; Zhu, S | 1 |
| Giulivi, C | 1 |
| Currie, MG; Highkin, MK; Manning, PT; Misko, TP; Salvemini, D; Stern, MK; Veenhuizen, AW | 1 |
| Hinson, JA; Mayeux, PR; Pike, SL; Pumford, NR | 1 |
| Alvarez, B; Ferrer-Sueta, G; Radi, R | 1 |
| Ara, J; Horwitz, J; Ischiropoulos, H; Jackson-Lewis, V; Naini, AB; Przedborski, S; Trifiletti, RR | 1 |
| Dolder, M; Richter, C; Stachowiak, O; Wallimann, T | 1 |
| Damais, C; Dornand, J; Dugas, B; Dugas, N; Gross, A; Kolb, JP; Spiesser, S; Vouldoukis, I | 1 |
| Leza, JC; Lizasoain, I; Lorenzo, P; Moro, MA | 1 |
| Chumley, P; Freeman, BA; Houston, M; Radi, R; Rubbo, H | 1 |
| Han, Y; Hirota, S; Hou, J; Xin, W; Zhao, B; Zhao, W | 1 |
| Adam, JM; Bradley, NJ; Bruckdorfer, KR; Ettelaie, C; James, NJ; Naseem, KM | 1 |
| Choe, N; Hemenway, DR; Kagan, E; Matalon, S; Tanaka, S; Zhu, S | 1 |
| Endres, M; Huang, PL; Moskowitz, MA; Namura, S; Salzman, AL; Scott, G; Szabó, C | 1 |
| Bohle, DS | 1 |
| Marnett, LJ | 1 |
| Bartberger, MD; Houk, KN; Olson, LP | 2 |
| Koppenol, WH | 3 |
| Caputi, AP; Cuzzocrea, S; Longo, G; Villari, D; Zingarelli, B | 1 |
| Beckman, JS; Crow, JP; Sopper, MM; Strong, MJ; Strong, WL | 1 |
| Bassenge, E; Dikalov, S; Grigor'ev, IA; Voinov, M | 1 |
| Baier-Bitterlich, G; Fuchs, D; Wede, I; Widner, B; Wirleitner, B | 1 |
| Chen, B; Deen, WM; Keshive, M | 1 |
| Corbett, SA; Hughes, SP; Hukkanen, M; Konttinen, YT; Platts, LA; Polak, JM; Santavirta, S | 1 |
| Beckman, JS; Bredesen, DE; Estévez, AG; Johnson, GV; Spear, N; Thompson, JA | 1 |
| Crawford, F; Fang, C; Humphrey, J; Mullan, M; Paris, D; Parker, TA; Suo, Z; Town, T | 1 |
| De Sarno, P; Jope, RS | 1 |
| Benkusky, NA; Kooy, NW; Lewis, SJ | 2 |
| Hayward, R; Jensen, D; Lefer, AM; Nossuli, TO; Scalia, R | 1 |
| Filep, JG; Gagnon, C; Leblond, FA | 1 |
| Loft, S; Poulsen, HE; Tuo, J; Wolff, SP | 1 |
| Cross, AH; Keeling, RM; Manning, PT; Misko, TP; Schmidt, RE | 1 |
| Lu, M; Wang, WH | 1 |
| Demiryürek, AT; Kanzik, I; Sahin-Erdemli, I; Yildiz, G | 1 |
| Caputi, AP; Costantino, G; Cuzzocrea, S; Zingarelli, B | 3 |
| Rabelink, TJ; Stroes, E; Wever, R | 1 |
| Bassenge, E; Dikalov, S; Fink, B; Skatchkov, M; Stalleicken, D | 1 |
| Choe, N; Kagan, E; Tanaka, S | 1 |
| Chen, HS; Choi, YB; Lipton, SA; Sucher, NJ | 1 |
| Crow, JP | 3 |
| Evans, TJ; Mason, NA; Polak, JM; Pomerance, A; Springall, DR; Yacoub, MH | 1 |
| Dawson, VL; Szabó, C | 1 |
| Mohanakumar, KP; Steinbusch, HW | 1 |
| Beckman, JS; Rosen, H; Sampson, JB; Ye, Y | 1 |
| Ducastel, B; Guittet, O; Henry, Y; Lemaire, G; Lepoivre, M; Rubin, H; Salem, JS | 1 |
| Bounds, PL; Koppenol, WH; Pande, AK; Scheidegger, R | 1 |
| Grisham, MB; Jourd'heuil, D; Miles, AM; Mills, L | 1 |
| Barnes, PJ; Ernst, P; Giaid, A; Lim, S; Saleh, D | 1 |
| Gon, Y; Hashimoto, N; Kikuchi, H; Nishiyama, A; Nozaki, K; Sono, H; Takagi, Y; Todaka, T; Yodoi, J | 1 |
| Kim, D; Packer, L; Virgili, F | 1 |
| Graham, A; Owen, JS; Vinogradov, DV | 1 |
| Endres, M; Kun, E; Moskowitz, MA; Salzman, AL; Scott, GS; Szabó, C | 1 |
| Allix, M; Boulu, RR; Charriaut-Marlangue, C; Mésenge, C; Plotkine, M; Verrecchia, C | 1 |
| Gorren, AC; Mayer, B | 1 |
| Akaike, T; Maeda, H | 1 |
| Khadour, FH; Panas, D; Schulz, R; Szabó, C | 1 |
| Quinn, MT; Rohn, TT | 1 |
| Fakhrzadeh, L; Gardner, CR; Heck, DE; Laskin, DL; Laskin, JD; Weinberger, B | 1 |
| Deby, C; Deby-Dupont, G; Hans, P; Hoebeke, M; Lamy, M; Mouithys-Mickalad, A | 1 |
| Barnes, S; Darley-Usmar, V; Kirk, M; Parks, DA; Patel, R; Skinner, KA; Tan, S; White, CR | 1 |
| Hara, A; Hibino, Y; Higo, A; Katsura, M; Ohkuma, S | 1 |
| Hogg, N; Kalyanaraman, B | 1 |
| Helton, ES; Jackson, RM; Parish, G | 1 |
| Bolzan, RM; Lemercier, JN; Pryor, WA; Squadrito, GL; Uppu, RM; Zhang, H | 1 |
| Caputi, AP; Costantino, G; Cuzzocrea, S | 2 |
| Salzman, AL; Szabó, C; Virág, L | 1 |
| Mayer, B; Pfeiffer, S | 1 |
| Gurwitz, D; Kloog, Y | 1 |
| Cuzzocrea, S; Marmer, D; Salzman, AL; Scott, GS; Szabó, C; Virág, L | 1 |
| Fujimoto, Y; Fujita, T; Ogawa, K; Sakuma, S; Tagano, S | 1 |
| Kim, WK; Ko, KH | 1 |
| Chen, C; Mori, A; Wei, T; Xin, W; Zhao, B | 1 |
| Richter, C | 1 |
| Weinberg, JB | 1 |
| Allen, JB; Keng, T; Privalle, C | 1 |
| Choe, N; Kagan, E; Manuel, M; Matalon, S; Tanaka, S; Zhu, S | 1 |
| Fukuyama, N; Nakazawa, H | 1 |
| Davies, KJ; Grune, T; Kuckelkorn, U; Reinheckel, T; Sitte, N; Ullrich, O | 1 |
| Hara, A; Hibino, Y; Higo, A; Katsura, M; Ohkuma, S; Tarumi, C | 1 |
| Fukuyama, N; Genka, C; Ishida, H; Nakazawa, H; Su, Z; Todorov, R | 1 |
| Blaylock, MG; Cuthbertson, BH; Ferguson, NR; Galley, HF; Webster, NR | 1 |
| Böhm, F; Edge, R; McGarvey, DJ; Truscott, TG | 1 |
| Abdalla, DS; da Silva, EL | 1 |
| Bast, A; Cross, CE; Hoen, PA; van der Vliet, A; Wong, PS | 1 |
| Okatani, Y; Sagara, Y; Tamura, S; Wakatsuki, A; Watanabe, K | 1 |
| Castro, LA; Cayota, A; Meneghini, R; Radi, R; Robalinho, RL | 1 |
| Aguirre, DE; Fink, MP; Menconi, MJ; Smith, M; Unno, N | 1 |
| Huschenbett, J; Michaelis, ML; Zaidi, A | 1 |
| Brzezinska, AK; Chilian, WM; Elliott, SJ; Lacey, DJ | 1 |
| Rubbo, H | 1 |
| Johnson, D; Mayers, I | 1 |
| Asada, S; Fukuda, K; Oh, M; Tanaka, S; Yasuda, Y | 1 |
| Baron, C; Beauchamp, M; Filep, JG; Paquette, Y | 1 |
| Klein, T; Pasquet, JP; Ullrich, V; Zou, MH | 1 |
| Cross, CE; Eiserich, JP; Goldkorn, T; Hristova, M; van der Vliet, A | 1 |
| Balazy, M; Kaminski, PM; Mao, K; Tan, J; Wolin, MS | 1 |
| Kerry, N; Rice-Evans, C | 2 |
| Boggs, SE; Hellberg, CB; Lapetina, EG | 1 |
| Halliwell, B; Jenner, P; Marshall, KA; Reist, M | 2 |
| Salzman, AL; Southan, GJ; Szabó, C | 1 |
| Kachel, DL; Martin, WJ; Matalon, S; Zhu, S | 1 |
| Bryan, TW; Grisham, MB; Jinkins, PA; Jones, KL; Markewitz, BA; Milligan, SA; Owens, MW; Robbins, RA; Simpson, KL | 1 |
| Ahmed, F; Anthony, GM; Bank, N; Fabry, ME; Kiroycheva, M; Nagel, RL; Singhal, PC | 1 |
| Cantoni, O; Clementi, E; Guidarelli, A; Sciorati, C | 1 |
| Daiber, A; Mehl, M; Ullrich, V | 1 |
| Radi, R; Souza, JM | 1 |
| Briviba, K; Kissner, R; Koppenol, WH; Sies, H | 1 |
| Cuzzocrea, S; Salzman, AL; Szabó, C; Zingarelli, B | 1 |
| Auriol, S; Gilibert, I; Ohshima, H; Yoshie, Y | 1 |
| Marmer, DJ; Szabó, C; Virág, L | 1 |
| Alvarez, B; Ferrer-Sueta, G; Freeman, BA; Radi, R | 1 |
| Haramaki, N; Ikeda, H; Imaizumi, T; Mori, E | 1 |
| Chan, PH; Epstein, CJ; Kamii, H; Kinouchi, H; Mikawa, S; Yoshimoto, T | 1 |
| Bezold, G; Falke, KJ; Gerlach, H; Gerlach, M; Keh, D; Kürer, I; Peter, RU; Spielmann, S | 1 |
| Caputi, AP; Costantino, G; Cuzzocrea, S; Mazzon, E | 2 |
| Kruman, II; Mattson, MP; Nath, A | 1 |
| Charbonnet, RM; Clark, DA; Liu, X; Mannick, EE; Miller, MJ; Sadowska-Krowicka, H; Sandoval-Chacón, M; Thompson, JH; Zhang, XJ | 1 |
| Hogg, N; Joseph, J; Kalyanaraman, B; Konorev, E; Singh, RJ | 1 |
| Fisher, D; Ischiropoulos, H; Ohnishi, ST; Thom, SR; Xu, YA | 1 |
| Bettenhausen, L; Butterfield, DA; Drake, J; Jordan, B; Koppal, T; Varadarajan, S; Yatin, S | 1 |
| Jutila, KL; Nelson, LK; Quinn, MT; Rohn, TT; Sipes, KM; Swain, SD | 1 |
| Conklin, JL; Cullen, JJ; Herrmann, BW; Ledlow, A; Murray, JA | 1 |
| Rubanyi, GM | 1 |
| Cooper, CE; Sharpe, MA; Svistunenko, DA; Torres, J; Wilson, MT | 1 |
| Brown, AS; Cramer, EM; Darley-Usmar, V; Masse, JM; Moro, MA; Radomski, M | 1 |
| Barnes, S; Chumley, PH; Darley-Usmar, VM; Eiserich, JP; Freeman, BA; Jablonsky, MJ; Kirk, M; Krishna, NR; O'Donnell, VB | 1 |
| Jakeman, LB; Scott, GS; Stokes, BT; Szabó, C | 1 |
| Chen, JS; Chen, LW; Chen, SC; Hsu, CM; Wang, JS | 1 |
| Bolzan, RM; Cueto, R; Pryor, WA; Squadrito, GL; Uppu, RM | 1 |
| Darley-Usmar, V; Patel, RP; White, CR | 1 |
| Briviba, K; Klotz, LO; Sies, H | 1 |
| Ballmaier, D; Briviba, K; Epe, B; Sies, H | 1 |
| Pannala, AS; Rice-Evans, C; Singh, S | 1 |
| Evans, P; Halliwell, B; Whiteman, M | 1 |
| Denicola, A; Freeman, BA; Radi, R | 1 |
| Ghafourifar, P; Richter, C; Schweizer, M | 1 |
| Barbeito, L; Beckman, JS; Estévez, AG; Kamaid, A; Pelluffo, H; Spear, N | 1 |
| Genka, C; Ishida, H; Nakazawa, H | 1 |
| Barnes, S; Bloodsworth, A; Chumley, PH; Darley-Usmar, VM; Eiserich, JP; Freeman, BA; Kirk, M; O'Donnell, VB | 1 |
| Hoglen, NC; Liebler, DC | 1 |
| Cavallini, D; Fontana, M; Macone, A; Pecci, L | 1 |
| Herold, S | 3 |
| Davidge, ST; Roggensack, AM; Zhang, Y | 1 |
| Dawson, TM; Dawson, VL | 1 |
| Barbeito, L; Beckman, JS; Estévez, AG; Manuel, SM; Radi, R; Spear, N | 1 |
| Ananda Inalsingh, V; Cammack, R; Hughes, MN; Shergill, JK | 1 |
| da Costa Ferreira, AM; Danner, B; Scholes, CP; Sienkiewicz, A | 1 |
| Borutaite, V; Brown, GC; Morkuniene, R | 1 |
| Koedel, U; Pfister, HW | 1 |
| Felts, PA; Kapoor, R; Smith, KJ | 1 |
| Carthy, CM; Glysing-Jensen, T; Granville, DJ; Koglin, J; McManus, BM; Mudgett, JS; Russell, ME | 1 |
| Brockhaus, F; Brüne, B | 1 |
| Minetti, M; Pietraforte, D; Scorza, G | 1 |
| Czapski, G; Goldstein, S; Lind, J; Merényi, G | 4 |
| Gadelha, FR; Peluffo, G; Radi, R; Thomson, L; Vercesi, AE | 1 |
| Benjamins, JA; Boullerne, AI; Nedelkoska, L | 1 |
| Akizuki, E; Liang, J; Matsuda, T; Matsumura, F; Mori, K; Ogawa, M; Ohshiro, H; Okabe, K; Yamada, S; Yamaguchi, Y | 1 |
| Burney, S; Caulfield, JL; Niles, JC; Tannenbaum, SR; Wishnok, JS | 1 |
| Goodwin, DC; Landino, LM; Marnett, LJ | 2 |
| Baker, CS; Creminon, C; Evans, TJ; Hall, RJ; Maclouf, J; Polak, JM; Pomerance, A; Yacoub, MH | 1 |
| Bolaños, JP; Brookes, PS; Clark, JB; Heales, SJ; Land, JM; Stewart, VC | 1 |
| Abe, T; Ishizaki, E; Isobe, C; Murata, T; Tohgi, H; Yamazaki, K | 1 |
| Beckman, JS; Macfadyen, AJ; Reiter, C; Zhuang, Y | 1 |
| Jensen, MP; Rusnak, F; Stern, MK; Wengenack, NL | 1 |
| Böhm, M; Cremers, B; Flesch, M; Kilter, H; Laufs, U; Müller, FU; Ortmann, M; Südkamp, M | 1 |
| Paine, AJ; Rodriguez-Ariza, A | 1 |
| Eguchi, H; Koh, YH; Park, YS; Suzuki, K; Taniguchi, N | 1 |
| Brito, C; Cayota, AM; Dighiero, G; Gualco, G; Naviliat, M; Radi, R; Tiscornia, AC; Vuillier, F | 1 |
| Arteel, GE; Briviba, K; Sies, H | 1 |
| Balazy, M; Jiang, H | 1 |
| Dweck, HS; Hassan, MS; Mileva, MM; Rosenfeld, L | 1 |
| Arteel, GE; Bradford, BU; Kadiiska, MB; Mason, RP; Raleigh, JA; Rusyn, I; Thurman, RG | 1 |
| Butterfield, DA; Drake, J; Koppal, T | 1 |
| Lobysheva, II; Serezhenkov, VA; Vanin, AF | 1 |
| Szabó, C; Virág, L | 3 |
| Hirata, K; Kanazawa, H; Okamoto, T; Shiraishi, S; Yoshikawa, J | 1 |
| Stanbro, WD | 4 |
| Augusto, O; Bonini, MG; Ferreira, AM; Ferrer-Sueta, G; Radi, R | 1 |
| Regoli, F; Winston, GW | 1 |
| Miller, MJ; Sandoval, M | 1 |
| Boven, LA; Gomes, L; Gray, F; Hery, C; Nottet, HS; Portegies, P; Tardieu, M; Verhoef, J | 1 |
| Fujii, T; Nakaki, T | 1 |
| Kissner, R; Koppenol, WH; Latal, P; Nesper, R; Wörle, M | 1 |
| Niki, E; Noguchi, N; Shi, H; Xu, Y | 1 |
| Clark, JE; Foresti, R; Green, CJ; Motterlini, R; Sarathchandra, P | 1 |
| Calingasan, NY; Gibson, GE; Kristal, BS; Lindsay, JG; Park, LC; Sheu, KF; Zhang, H | 1 |
| Jendral, M; Ullrich, V; Zou, M | 1 |
| Briviba, K; Klotz, LO; Schieke, SM; Sies, H | 1 |
| Aeschbach, R; Aruoma, OI; Banni, S; Bianchi, ML; Corongiu, FP; Deiana, M; Dessi, MA; Halliwell, B; Kaur, H; Spencer, JP | 1 |
| Fridovich, I; Liochev, SI | 3 |
| Gibbs-Erwin, J; Hickman-Davis, J; Lindsey, JR; Matalon, S | 1 |
| Asagiri, K; Kamada, Y; Kimura, Y; Kudo, T; Nakatsuka, M; Tada, K | 1 |
| Espey, MG; Grisham, MB; Jourd'heuil, D; Kim, SM; Laroux, S; Mai, CT; Miles, AM; Miranda, KM; Vodovotz, Y; Wink, DA | 1 |
| Akhter, S; Mutus, B; Redmond, RW | 1 |
| Groves, JT | 1 |
| Roberts, LJ; van der Veen, RC | 1 |
| Dimmeler, S; Haendeler, J; Zeiher, AM | 1 |
| Fung, HL; Maurer, TS; Tabrizi-Fard, MA | 1 |
| Hughes, MN | 1 |
| Brown, GC | 1 |
| Darley-Usmar, VM; Freeman, BA; Jo, H; McAndrew, J; Patel, RP; Sellak, H; White, CR | 1 |
| Almeida, A; Bolaños, JP | 1 |
| Preiser, JC; Szabó, C | 1 |
| Halliwell, B; Szabó, C; Whiteman, M | 1 |
| Batinić-Haberle, I; Ferrer-Sueta, G; Fridovich, I; Radi, R; Spasojević, I | 1 |
| Burney, S; Niles, JC; Tannenbaum, SR; Tretyakova, NY; Wishnok, JS | 1 |
| Brdiczka, D; Jahnke, D; Schlattner, U; Schmidt, A; Soboll, S; Wallimann, T; Wendt, S; Wyss, M | 1 |
| Baker, PN; Davidge, ST; Guilbert, LJ; Smith, SC; Yui, J | 1 |
| Fumelli, P; Mazzanti, L; Moretti, N; Mutus, B; Rabini, RA; Tannous, M; Vignini, A; Zielinski, B | 1 |
| MacMillan-Crow, LA; Thompson, JA | 1 |
| Ullrich, V; Yesilkaya, A; Zou, M | 1 |
| Fukuda, J; Kagabu, S; Karube, A; Kodama, H; Murata, M; Tanaka, T | 1 |
| Blazar, BR; Haddad, IY; Ingbar, DH; Milla, CE; Panoskaltsis-Mortari, A; Yang, S | 1 |
| Clayton, HA; Green, IC; Green, MH; Hadjivassiliou, V; James, RF; Swift, SM | 1 |
| Freeman, BA; Radi, R; Richardson, G; Suarez, E; Tarpey, MM; White, CR | 1 |
| Edelstein, CL; Gengaro, PE; Ling, H; Nemenoff, RA; Schrier, RW; Wangsiripaisan, A | 1 |
| Balavoine, GG; Geletii, YV | 1 |
| Bigelow, DJ; Ferrington, DA; Schöneich, C; Viner, RI; Williams, TD | 1 |
| Feelisch, M; Frey, A; Fröhlich, LG; Hofmann, H; Kotsonis, P; Reif, A; Schmidt, HH; Wink, DA | 1 |
| Deby, C; Deby-Dupont, G; Kohnen, S; Lamy, M; Mouithys-Mickalad, A; Noels, AF | 1 |
| Muscará, MN; Wallace, JL | 1 |
| Ferdinandy, P; Panas, D; Schulz, R | 1 |
| Barker, SL; Kopelman, R; Marletta, MA; Zhao, Y | 1 |
| Burney, S; Dedon, PC; Niles, JC; Tannenbaum, SR | 1 |
| Pryor, WA; Squadrito, GL; Uppu, R; Zhang, H | 1 |
| Gordge, MP; Hirayama, A; Hothersall, JS; Neild, GH; Noronha-Dutra, AA | 2 |
| Celan, I; Chazotte, L; Mower, HF; Ohshima, H; Pignatelli, B | 1 |
| Daiber, A; Herold, S; Mehl, M; Shoun, H; Ullrich, V | 1 |
| Davis, AR; Nelson, LK; Quinn, MT; Rohn, TT | 1 |
| Hinson, JA; Mayeux, PR; Michael, SL; Niesman, MR; Pumford, NR | 1 |
| Bordini, E; Hamdan, M | 1 |
| Berlett, BS; Chock, PB; Levine, RL; Stadtman, ER; Tien, M | 1 |
| Kanesaki, T; Maeda, S; Matsumoto, K; Ooi, Y; Saeki, M; Saito, K; Sakuda, M; Suematsu, M | 1 |
| Caputi, AP; Costantino, G; Cuzzocrea, S; Mazzon, E; Micali, A; Zingarelli, B | 1 |
| Aruoma, OI | 1 |
| Currie, MG; Lennon, PJ; Macarthur, H; Misko, TP; Riley, DP; Salvemini, D; Wang, ZQ | 1 |
| Amirmansour, C; Bogle, RG; Vallance, P | 1 |
| Maeda, S; Saeki, M | 1 |
| Hara, A; Hokari, S; Honda, T; Inoue, I; Katayama, S; Kawai, S; Kobayashi, J; Komoda, T; Matsunaga, T; Nakajima, T; Satomi, A; Sonoda, M | 1 |
| Cunha, FQ; Hothersall, J; Noronha-Dutra, A; Teixeira, MM | 1 |
| Eliasson, MJ; Ferrante, RJ; Huang, Z; Molliver, ME; Moskowitz, MA; Sasamata, M; Snyder, SH | 1 |
| Kanadia, RN; Kuo, WN; Shanbhag, VP | 1 |
| Holm, P; Kankaanranta, H; Knowles, RG; Moilanen, E; Oja, SS | 1 |
| Bauersachs, J; Bouloumié, A; Busse, R; Ertl, G; Fraccarollo, D; Hu, K | 1 |
| Denicola, A; Radi, R; Romero, N; Souza, JM | 1 |
| Helton, E; Jackson, RM; Parish, G | 1 |
| Di Stasi, AM; Macchia, G; Mallozzi, C; Minetti, M; Petrucci, TC | 1 |
| Akaike, T; Endoh, N; Ichinose, M; Koarai, A; Maeda, H; Mashito, Y; Miura, M; Ohuchi, Y; Oyake, T; Shirato, K; Sugiura, H; Yamagata, S | 1 |
| Grisham, MB; Koyama, S; Robbins, RA; Sato, E; Simpson, KL | 5 |
| Ali, SF; Crow, JP; Imam, SZ; Islam, F; Newport, GD; Slikker, W | 1 |
| Arnal, JF; Barbacanne, MA; Bayard, F; Besombes, JP; Michel, JB; Philippe, M; Rami, J; Souchard, JP | 1 |
| Bär, PR; Joosten, EA; Kaal, EC; Kil, AC; Sodaar, P | 1 |
| Barnes, S; Boersma, BJ; Darley-Usmar, VM; Jackson, PL; Kirk, M; Muccio, D; Patel, RP | 1 |
| Lehnig, M | 1 |
| Guissani, A; Henry, Y | 1 |
| Blanchard, B; Ducrocq, C; Ohshima, H; Pignatelli, B | 1 |
| Duchstein, HJ; Erbach, C; Riederer, S | 1 |
| Anderson, RL; Hurley, JV; Lepore, DA; Morrison, WA; Stewart, AG; Tomasi, A | 1 |
| Callahan, LA; DiMarco, A; Nethery, D; Nosek, TM; Stofan, D; Supinski, G | 1 |
| Borutaité, V; Brown, GC; McBride, AG | 1 |
| Bartosz, G; Bartosz, M | 1 |
| de Groot, H; Kirsch, M | 3 |
| Aubier, M; Boczkowski, J; Boveris, A; Carreras, MC; Lanone, S; Lisdero, CL; Poderoso, JJ; Samb, A | 1 |
| Alexander, JS; Eppihimer, LA; Grisham, MB; Kevil, CG; Okayama, N; Wink, DA | 1 |
| Hiai, H; Imamura, M; Iwasa, Y; Kondo, S; Onodera, H; Tanaka, T; Toyokuni, S | 1 |
| Aykaç-Toker, G; Kervancioğlu, E; Koçak, T; Koçak-Toker, N; Oztezcan, S; Türkoğlu, UM | 1 |
| Caputi, AP; Costantino, G; Cuzzocrea, S; Sottile, A; Teti, D; Zingarelli, B | 1 |
| Brown, LA; Fortenberry, JD; Owens, ML; Raghuram, N | 1 |
| Brain, SD; Evans, P; Greenacre, SA; Halliwell, B | 1 |
| Kastenbauer, S; Koedel, U; Pfister, HW | 1 |
| Gupte, SA; Iesaki, T; Kaminski, PM; Wolin, MS | 1 |
| Bouton, C | 1 |
| Guittet, O; Lepoivre, M; Roy, B | 1 |
| Beckman, JS; Crow, JP; MacMillan-Crow, LA; Takakura, K | 1 |
| Cotman, CW; Deng, G; Ivins, KJ; Su, JH; Van Houten, B | 1 |
| Akiyama, K; Aoyagi, K; Hirayama, A; Koyama, A; Nagase, S; Narita, M; Ohba, S; Shahrzad, S; Takemura, K; Tomida, C | 1 |
| Bauer, JA; Coyle, CM; Jing, L; Mihm, MJ | 1 |
| Isobe, K; Maruyama, W; Naoi, M; Oh-hashi, K; Takahashi, T; Yi, H | 1 |
| Schöneich, C; Viner, RI; Williams, TD | 2 |
| Deeb, RS; Hajjar, DP; Upmacis, RK | 1 |
| Morioka, N; Okatani, Y; Wakatsuki, A; Watanabe, K | 1 |
| Caputi, AP; Ciliberto, G; Costantino, G; Cuzzocrea, S; De Sarro, A; De Sarro, G; Mazzon, E | 1 |
| Antal-Szalmás, P; O'Connor, M; Ohshima, H; Scott, GS; Szabó, C; Viráģ, L | 1 |
| Genka, C; Hamasaki, Y; Hirota, Y; Ishida, H; Nakazawa, H | 1 |
| Keilhoff, G; Noack, H; Possel, H; Rethfeldt, C; Wolf, G | 1 |
| Almeida, A; Bolaños, JP; Heales, SJ; Medina, JM; Vega-Agapito, V | 1 |
| Allen, BS; Halldorsson, A; Ilbawi, M; Kronon, MT; Rahman, S; Wang, T | 2 |
| Perry, G; Sayre, LM; Smith, MA | 1 |
| Haskó, G; Salzman, AL; Szabó, C; Zingarelli, B | 1 |
| Baker, C; Evans, TW; Gutteridge, JM; Lamb, NJ; Quinlan, GJ | 1 |
| Doi, U; Kato, Y; Niwa, T; Osawa, T | 2 |
| Katusic, Z; Milstien, S | 1 |
| Fujita, M; Hotta, Y; Ishikawa, N; Kawai, N; Kohno, M; Liu, W; Masumizu, T; Nakagawa, J; Otsuka-Murakami, H; Yajima, M | 1 |
| Geddes, TJ; Kuhn, DM | 1 |
| Du, X; Rösen, P; Stocklauser-Färber, K | 1 |
| Higuchi, H; Hokari, R; Ishii, H; Kimura, H; Miura, S; Mizumori, M; Mori, M; Sakaguchi, AA; Suzuki, H; Takeuchi, T; Yoshida, H | 1 |
| Michaelis, ML; Zaidi, A | 1 |
| Allescher, HD; Koppitz, P; Kurjak, M; Schusdziarra, V | 1 |
| Beckman, JS; Darley-Usmar, VM; Go, YM; Jo, H; Maland, MC; Park, H; Patel, RP | 1 |
| Cudic, M; Dendane, M; Ducrocq, C; Houé-Levin, C | 1 |
| Guérin, M; Salman-Tabcheh, S; Torreilles, F; Torreilles, J | 1 |
| Augusto, O; Nakao, LS; Ouchi, D | 1 |
| Burk, RF; Hill, KE; Hondal, RJ; Motley, AK | 1 |
| Caputi, AP; Ciliberto, G; Costantino, G; Cuzzocrea, S; De Sarro, A; De Sarro, G; Di Rosa, M; Ialenti, A; Mazzon, E; Rombolà, L; Sautebin, L; Thiemermann, C | 1 |
| Ghafourifar, P; Klein, SD; Richter, C; Schenk, U | 1 |
| Arstall, MA; Fukazawa, R; Kelly, RA; Sawyer, DB | 1 |
| Kanadia, RN; Kuo, WN; Morgan, R; Shanbhag, VP | 1 |
| Cheng, XS; Egashira, K; Fukuyama, N; Momii, H; Nakazawa, H; Oyama, J; Shimokawa, H; Takeshita, A | 1 |
| Althaus, R; Eugster, HP; Frei, K; Fröhlich, D; Müller, M | 1 |
| Caputi, AP; Costantino, G; Cuzzocrea, S; Mazzon, E; Reiter, RJ; Tan, DX | 1 |
| Daikhin, E; Ischiropoulos, H; Raman, CS; Souza, JM; Yudkoff, M | 1 |
| Albrecht, S; Distler, W; Grützmann, R; Saeger, HD; Scheller, D; Zimmermann, T | 1 |
| Asai, Y; Esaki, T; Hayashi, T; Iguchi, A; Jayachandran, M; Kano, H; Kumar Thakur, N; Sumi, D; Yamada, K | 1 |
| Hasegawa, K; Ochiai-Kanai, R; Sawada, T; Takeuchi, Y; Yoshioka, H | 1 |
| Caputi, AP; Cuzzocrea, S; El-Sokkary, GH; Hassanein, AF; Reiter, RJ; Tan, DX | 1 |
| Aruoma, OI; Mahmood, N; Spencer, JP | 1 |
| Guyton, RA; Han, D; Katzmark, SL; Ma, XL; Nakamura, M; Ronson, RS; Thourani, VH; Vinten-Johansen, J; Zhao, ZQ | 1 |
| Aleryani, S; Kostka, P; Milo, E | 1 |
| Bartosz, G; Biliński, T; Jakubowski, W | 1 |
| Bhabra, MS; Hooper, TL; Hopkinson, DN; Shaw, TE | 1 |
| Heinecke, JW; Jackson-Lewis, V; Pennathur, S; Przedborski, S | 1 |
| Aretha, CW; Geddes, TJ; Kuhn, DM | 1 |
| Caputi, AP; Costantino, G; Cuzzocrea, S; De Sarro, A; Mazzon, E | 1 |
| Arteel, GE; Sies, H | 2 |
| Chesnais, JM; Fischmeister, R; Mery, PF | 1 |
| Hastings, TG; LaVoie, MJ | 1 |
| Toda, N | 1 |
| Pearce, LL; Peterson, J; Pitt, BR | 1 |
| Cheung, R; Mutus, B; Tannous, M; Vignini, A | 1 |
| Akaike, T; Maeda, H; Maruo, K; Okamoto, T; Wu, J | 1 |
| Anjos, EI; Augusto, O; Santos, CX | 1 |
| Alber, S; Boyle, P; Dickinson, E; Ford, H; Nadler, E; Tuncer, R; Watkins, S | 1 |
| Aust, AE; Eveleigh, JF | 1 |
| Kitzmiller, JA; Salzman, AL; Southan, GJ; Szabó, C; Wilmott, RW | 1 |
| Altug, S; Cakici, I; Demiryürek, AT; Kanzik, I | 1 |
| Nakamura, M; Ronson, RS; Vinten-Johansen, J | 1 |
| Barbeito, L; Beckman, JS; Crow, JP; Estévez, AG; Reiter, C; Richardson, GJ; Sampson, JB; Tarpey, MM; Zhuang, Y | 1 |
| Briviba, K; Panasenko, OM; Sharov, VS; Sies, H | 1 |
| Angeletti, M; Coletta, M; Eleuteri, AM; Fioretti, E; Lupidi, G; Tacconi, L | 1 |
| Dewez, B; Di Mascio, P; Garcia, CR | 1 |
| Elstner, EF; Schneider, D | 1 |
| Kruman, II; Mattson, MP; Pedersen, WA; Springer, JE | 1 |
| Kanadia, RN; Kuo, WN; Shanbhag, VP; Toro, R | 1 |
| Goss, SP; Hogg, N; Kalyanaraman, B; Singh, RJ | 1 |
| Halliwell, B; Whiteman, M; Zhao, K | 1 |
| Briviba, K; Sharov, VS; Sies, H | 1 |
| Nakazawa, H; Prónai, L; Szaleczky, E; Tulassay, Z | 1 |
| Hirata, K; Kanazawa, H; Yoshikawa, J | 2 |
| Beckman, JS; Darley-Usmar, V; Digerness, SB; Harris, KD; Kirklin, JW; Urthaler, F; Viera, L | 1 |
| Kavdia, M; Lewis, RS; Stanfield, JL | 1 |
| López-García, MP; Sanz-González, SM | 1 |
| Arteel, GE; Engman, L; Jacob, C; Kanda, T; Sies, H | 1 |
| Ali, SF; Imam, SZ | 2 |
| Cantoni, O; Clementi, E; Guidarelli, A; Sciorati, C; Sestili, P | 1 |
| Fisher, D; Ischiropoulos, H; Notarfrancesco, K; Thom, SR; Xu, YA | 1 |
| Jan, KY; Liu, F | 1 |
| Maruyama, W; Naoi, M | 1 |
| Bauer, JA; Holycross, BJ; Wattanapitayakul, SK; Weinstein, DM | 1 |
| Packer, L; Park, YC; Rimbach, G; Virgili, F | 1 |
| Duc, NM; Ichiishi, E; Kasai, R; Konoshima, T; Murakami, T; Nishino, H; Takasaki, M; Tokuda, H; Yamasaki, K | 1 |
| Brown, K; Frappier, TF; Friedman, WJ; Rabacchi, SA; Shelanski, ML; Troy, CM | 1 |
| Chiueh, CC | 1 |
| Althaus, JS; Hall, ED; Kupina, NC | 1 |
| Hake, P; Salzman, AL; Scott, GS; Szabo, C; Zingarelli, B | 1 |
| McCafferty, DM | 1 |
| Fukuyama, N; Hirabayashi, H; Nakazawa, H; Shinohara, Y; Takizawa, S | 2 |
| Sakihama, Y; Yamasaki, H | 1 |
| Christopher, TA; Gao, F; Lopez, BL; Ma, XL; Vinten-Johansen, J | 1 |
| Bernstein, C; Bernstein, H; Hoglen, N; Payne, CM; Washo-Stultz, D | 1 |
| Ault, SG; Hinson, JA; Michael, SL; Pumford, NR | 1 |
| Carbonell, T; Mitjavila, MT; Ródenas, J | 1 |
| Hayakawa, A; Hayashi, S; Kobayashi, T; Negita, M; Ogawa, H; Takagi, H; Yokoyama, I | 1 |
| Andersen, CB; Hansen, PR; Holm, AM; Olsen, PS; Svendsen, UG | 1 |
| Ikota, N; Matsushima, Y; Nakagawa, H; Ozawa, T; Sumiki, E; Takusagawa, M | 1 |
| Caputi, AP; Costantino, G; Cuzzocrea, S; Filipe, HM; Mazzon, E; McDonald, MC; Santagati, S; Thiemermann, C | 1 |
| Beckman, JS; Estévez, AG; Teng, R; Viera, L | 1 |
| Desai, M; Frenkel, K; Geacintov, NE; Khan, AU; Kolbanovskiy, A; Kovacic, D | 1 |
| Beuscher, N; Dornisch, K; Elstner, EF; Grassmann, J; Hippeli, S; Rohnert, U | 1 |
| Daiber, A; Peterson, JA; Shoun, H; Ullrich, V; Zou, MH | 1 |
| Mayer, M | 1 |
| Lee, CI; Liu, X; Zweier, JL | 1 |
| Balazy, M; Boulos, C; Jiang, H | 1 |
| Frangos, JA; Suzuki, R | 1 |
| Brain, SD; Greenacre, SA; Rawlingson, A | 1 |
| Hooper, DC; Kean, RB; Koprowski, H; Mikheeva, T; Scott, GS; Spitsin, SV; Zborek, A | 1 |
| Briviba, K; Buchczyk, DP; Hartl, FU; Sies, H | 1 |
| Brockman, D; Eis, A; Kossenjans, W; Myatt, L; Sahay, R | 1 |
| Burney, S; Dedon, PC; Pamir, B; Tannenbaum, SR; Tretyakova, NY; Wishnok, JS; Wogan, GN | 1 |
| Hirouchi, M; Itoh, Y; Oka, M; Ukai, Y | 1 |
| Aoyama, K; Fujikawa, Y; Hayase, N; Kobayashi, S; Matsubara, K; Nagahiro, Y; Shimizu, K; Shiono, H; Umegae, N | 1 |
| Decottignies, P; Guittet, O; Henry, Y; Laprévote, O; Le Maréchal, P; Lepoivre, M; Serani, L | 1 |
| Cassina, AM; Castro, L; Freeman, BA; Hodara, R; Ischiropoulos, H; Radi, R; Souza, JM; Thomson, L | 1 |
| Knight, KR; Liu, T; Tracey, DJ | 1 |
| Gebicka, L; Gebicki, JL | 1 |
| Du, L; Hong, JS; Liu, B | 1 |
| Exner, M; Herold, S | 1 |
| Althaus, JS; Borosky, S; Carroll, RT; Galatsis, P; Hall, ED; Kopec, KK; Kumar, V | 1 |
| Celan, I; Friesen, MD; Masuda, M; Mower, HF; Nishino, H; Ohshima, H; Pignatelli, B | 1 |
| Cueto, R; Pryor, WA; Splenser, AE; Squadrito, GL; Uppu, RM; Valavanidis, A; Zhang, H | 1 |
| Jope, RS; Song, L; Zhang, L | 1 |
| Augusto, O; Bonini, MG; Santos, CX | 1 |
| Ishikawa, Y; Kitamura, M; Lucio-Cazana, J; Moreno-Manzano, V | 1 |
| Kanaori, K; Makino, K; Morii, T; Suzuki, T; Tajima, K; Yamada, M | 1 |
| Cantoni, O; Guidarelli, A; Palomba, L | 1 |
| Altug, S; Demiryürek, AT; Kane, KA; Kanzik, I | 1 |
| Choi, I; Finkel, B; Foust, RF; Gole, MD; Hertkorn, C; Ischiropoulos, H; Lanken, PN; Malcolm, S; Souza, JM | 1 |
| Basiouny, KF; Crow, JP; Matalon, S; Zhu, S | 1 |
| Okada, K | 1 |
| Pall, ML | 3 |
| Dodd, SM; Nott, CA; Thuraisingham, RC; Yaqoob, MM | 1 |
| Bruijn, LI; Burlingame, A; Cleveland, DW; Corson, LB; Huang, L; Liu, J; Williamson, TL | 1 |
| Bonvicini, P; Calò, L; Cantaro, S; Crepaldi, G; D'Angelo, A; Giannini, S; Nobile, M; Plebani, M; Semplicini, A | 1 |
| Ju, C; Kim, HC; Kim, WK; Ko, KH; Oh, YK; Ryu, JR; Shin, CY; Yoon, KN | 1 |
| Bonner, JC; Kagan, E; Wang, YZ; Zhang, P | 1 |
| Bradley, NJ; Bruckdorfer, KR; Jacobs, M; Khan, J; Low, SY; Naseem, KM; Sabetkar, M | 1 |
| Liaudet, L; Soriano, FG; Szabó, C | 1 |
| Ballinger, CA; Ballinger, SW; Burow, DL; Doan, R; Freeman, BA; Patterson, C; Runge, MS; Van Houten, B; Yakes, FM; Yan, CN; Young, CG | 1 |
| Cross, AH; Keeling, RM; Misko, TP; Salvemini, D; San, M; Stern, MK | 1 |
| Bachschmid, M; Daiber, A; Ullrich, V; Zou, MH | 1 |
| Mayeux, PR; Walker, LM; Zhang, C | 1 |
| Ando, M; Okamoto, T; Suga, M | 1 |
| Bechara, EJ; Bidart, KA; Christoff, M; Knudsen, FS; Ouchi, D; Penatti, CA; Royer, LO | 1 |
| Niles, JC; Tannenbaum, SR; Wishnok, JS | 4 |
| Chen, Q; Darrah, PA; Hondalus, MK; Ischiropoulos, H; Mosser, DM | 1 |
| Ben-Ari, Y; Benjelloun, N; Charriaut-Marlangue, C; Ducrocq, S; Plotkine, M | 1 |
| Calhoun, W; Comhair, SA; Dweik, RA; Eissa, NT; Erzurum, SC; Guo, FH; Thomassen, MJ; Zheng, S | 1 |
| Mayhan, WG | 1 |
| Hikiji, H; Koizumi, T; Koizumi, Y; Okai-Matsuo, Y; Shin, WS; Susami, T; Takato, T; Toyo-Oka, T | 1 |
| Carbone, V; Marino, G; Minetti, M; Pietraforte, D; Salzano, AM; Scorza, G | 1 |
| Espey, MG; Miranda, KM; Wink, DA | 1 |
| Caputi, AP; Costantino, G; Cuzzocrea, S; Macarthur, H; Mazzon, E; Micali, A; Misko, TP; Salvemini, D | 1 |
| Cudic, M; Ducrocq, C | 1 |
| Chen, Q; Gole, M; Gow, AJ; Ischiropoulos, H; Lee, VM; Themistocleous, M | 1 |
| Routledge, MN | 1 |
| Brzezinska, AK; Chilian, WM; Elliott, SJ; Gebremedhin, D; Kalyanaraman, B | 1 |
| Koppenol, WH; Perrin, D | 1 |
| Greendorfer, JS; MacMillan-Crow, LA; Thompson, JA; Vickers, SM | 1 |
| Symons, MC | 1 |
| Doel, JJ; Durgan, J; Eisenthal, R; Godber, BL; Harrison, R | 1 |
| Agnew, DM; Brambrink, AM; Ichord, RN; Kaiser, A; Martin, LJ; Price, AC; Traystman, RJ | 1 |
| Alvarez, B; Boveris, A; Cadenas, E; Carreras, MC; Poderoso, JJ; Radi, R; Riobó, N; Schöpfer, F | 1 |
| Gutteridge, JM; Halliwell, B | 1 |
| Levine, RL; Stadtman, ER | 1 |
| Beukelman, CJ; Folkerts, G; Koster, AS; Muijsers, RB; Nijkamp, FP; Postma, DS; van Den Worm, E | 1 |
| Falcone, JC; Fleming, JT; Miller, FN; Pass, JM; Percival, SS; Saari, JT; Schuschke, DA; Young, SA | 1 |
| Fukuchi, Y; Maeda, K; Takahashi, F; Takahashi, K; Tominaga, S | 1 |
| Hinson, JA; Mayeux, PR; Walker, LM; Zhang, C | 1 |
| Bauer, JA; Mihm, MJ; Weinstein, DM | 1 |
| Haginaka, J; Kagota, S; Kunitomo, M; Yamaguchi, Y | 1 |
| Chen, SH; Kusmartsev, SA; Li, Y | 1 |
| Choi, IY; Ju, C; Kim, HC; Kim, WK; Ko, KH; Lee, SJ; Nam, W | 1 |
| Hu, Z; Lawler, JM | 1 |
| Chandrasekar, B; Freeman, GL; Melby, PC; Troyer, DA | 1 |
| Anthony, GM; Bank, N; Kiroycheva, M; Singhal, PC; Southan, GJ; Szabo, C | 1 |
| Bloodsworth, A; Freeman, BA; O'Donnell, VB | 1 |
| Tannenbaum, SR; Tretyakova, NY; Wishnok, JS | 1 |
| May, SW; Neumann, HM; Overcast, JD; Robertson, K; Woznichak, MM | 1 |
| Akaike, T; Kubota, T; Kuwahara, H; Maeda, H; Miyamoto, Y; Okamoto, S; Sawa, T | 1 |
| Clark, JB; Heales, SJ; Sharpe, MA; Stewart, VC | 1 |
| Akaike, T; Maeda, H; Sawa, T | 1 |
| Beckman, JS; Reiter, CD; Teng, RJ | 1 |
| Beckman, J; Crow, J; Darley-Usmar, V; Green, I; Patel, R; Spear, N; Thomas, S; White, R | 1 |
| Green, IC; Green, MH; Lowe, JE; Thomas, S | 1 |
| Simon, G; Zhuang, S | 1 |
| Adrie, C; Bachelet, M; Banzet, N; Dhainaut, JF; Dinh-Xuan, AT; François, D; Polla, BS; Richard, MJ; Richter, C | 1 |
| Arteel, GE; Schroeder, P; Sies, H | 1 |
| Chen, SS; Jou, LS; Kang, BH; Wang, HW; Weng, PK | 1 |
| Hu, Q; Lounsbury, KM; Ziegelstein, RC | 1 |
| Vinten-Johansen, J | 1 |
| Ambrus, I; Danial, H; Ferdinandy, P; Rothery, RA; Schulz, R | 1 |
| Bolay, H; Dalkara, T; Gürsoy-Ozdemir, Y; Saribaş, O | 1 |
| Choi, JH; Chung, HY; Kim, KW; Kim, MS; Lee, KH; Yang, R; Yokozawa, T | 1 |
| Ikeno, S; Kigawa, J; Nagata, N; Takahashi, H; Terakawa, N; Yoshida, S | 1 |
| Akali, KO; Chiang, KT; Fukuto, JM; Switzer, CH | 1 |
| Byrne, L; Croft, KD; Morton, LW; Puddey, IB | 1 |
| Bartosz, G; Grzelak, A; Soszyński, M | 1 |
| Muriel, P; Sandoval, G | 1 |
| Banan, A; Decker, H; Fields, JZ; Keshavarzian, A; Zhang, Y | 1 |
| Liaudet, L; Salzman, AL; Soriano, FG; Szabó, A; Szabó, C; Zingarelli, B | 1 |
| Caputi, AP; Costantino, G; Cuzzocrea, S; Filipe, HM; Mazzon, E; McDonald, MC; Thiemermann, C | 1 |
| Brovkovych, V; Huk, I; Malinski, T; Nanobashvili, J; Neumayer, C; Patton, S; Polterauer, P; Prager, M | 1 |
| Traber, DL | 1 |
| Akiba, J; Hikichi, T; Kado, M; Yanagiya, N; Yoshida, A | 1 |
| Kamisaki, Y; Maeda, S; Saeki, M | 2 |
| Hadeli, K; Hoyt, JC; Nelson, D; Robbins, RA; Sato, E | 1 |
| Fukuyama, N; Hayashi, Y; Matsuda, H; Nakazawa, H; Nishimura, M; Sawa, Y; Tojo, SJ | 1 |
| Crawford, JH; Darley-Usmar, VM; Levonen, A; Patel, RP | 1 |
| Bhattacharya, M; Chemtob, S; Dumont, I; Hardy, P; Hou, X; Lachapelle, P; Varma, DR | 1 |
| Caputi, AP; Costantino, G; Cuzzocrea, S; De Sarro, A; Mazzon, E; Serraino, I | 1 |
| Cheung, PY; Schulz, R; Wang, W | 1 |
| Kubes, P; McCafferty, DM | 1 |
| Chen, KJ; Chu, YR; Lin, JK; Lin-Shiau, SY; Liu, GY | 1 |
| Augusto, O; Bonini, MG; Briviba, K; Di Mascio, P; Herold, S; Koppenol, WH; Martinez, GR; Maurer, P; Röthlisberger, U; Sies, H | 1 |
| Lee, C; Liu, X; Miura, K; Zweier, JL | 1 |
| Liu, L; Loft, S; Poulsen, HE; Svendsen, O; Tuo, J; Weimann, A | 1 |
| Ackerman, A; Kalyanaraman, B; Pritchard, KA | 1 |
| Kendrick, KM; Trabace, L | 1 |
| Borutaite, V; Brown, GC | 1 |
| Ali, SF; Imam, SZ; Mayeux, PR; Walker, LM; Walker, PD | 1 |
| Hirota, Y; Hoshiai, K; Ichimori, K; Li, M; Nakazawa, H; Niu, XL; Yang, X | 1 |
| Brodsky, S; Ebin, Z; Goligorsky, MS; Jin, H; Li, H; Zhang, X | 1 |
| Hooper, DC; Kean, RB; Mikheeva, T; Scott, GS; Spitsin, SV | 2 |
| Buckley, BJ; Whorton, AR | 1 |
| Cooper, CE; Davies, NA | 1 |
| Borutaite, V; Brown, GC; Budriunaite, A | 1 |
| Katai, N; Shibuki, H; Uchida, K; Yodoi, J; Yoshimura, N | 1 |
| Ekelund, UE; Georgakopoulos, D; Hare, JM; Harrison, RW; Isoda, T; Kass, DA; Ozaki, M; Paolocci, N; Vandegaer, K | 1 |
| Hong, HJ; Loh, SH; Yen, MH | 1 |
| Austen, BM; Davies, H; Frears, ER | 1 |
| Beger, HG; Drapier, JC; Jung, M; Nussler, AK; Oliveira, L; Renia, L; Wang, A; Weidenbach, H | 1 |
| Butler, AR; Ridd, JH; Rutherford, TJ; Short, DM | 1 |
| Carreras, MC; Cherñavsky, A; Gatto, EM; Poderoso, JJ; Riobó, NA; Rubio, A; Satz, ML | 1 |
| Ortega Mateo, A | 1 |
| Celebi, H; Demiryürek, AT; Turan, NN | 1 |
| Cacho, J; Crespo, MD; Herrera, E; Klatt, P; Ramos, P | 1 |
| Ling, X; Liu, D; Liu, J; Wen, J | 1 |
| Blanchard, B; Ducrocq, C; Pompon, D | 1 |
| Bringold, U; Ghafourifar, P; Richter, C | 1 |
| Alvarez, S; Arnaiz, SL; Boveris, A; Carreras, MC; Poderoso, JJ; Schöpfer, F; Valdez, LB | 1 |
| Cai, L; Kang, YJ; Klein, JB | 1 |
| Bartosz, G; Grzelak, A; Mateja, A; Soszyński, M; Stepień, K; Wilczok, A; Wilczok, T; Zajdel, A | 1 |
| Akaike, T; Akizuki, E; Fujii, S; Maeda, H; Ogawa, M; Okamoto, S; Yamaguchi, Y | 1 |
| Duszyk, M; Kamosinska, B; Man, SF; Radomski, A; Radomski, MW | 1 |
| Daiber, A; Jung, C; Schmidt, P; Schöneich, C; Ullrich, V | 1 |
| Esteva, F; Fiteni, I; Iñarrea, P; Jimenez, P; Lanas, A; Ortego, J; Royo, Y; Soteras, F | 1 |
| Adhami, A; Bamberg, T; Chumley, P; Crow, J; Eiserich, JP; Estevez, A; Freeman, BA; Lang, JD | 1 |
| Cantoni, O; Clementi, E; Fiorani, M; Guidarelli, A; Palomba, L; Sciorati, C; Sestili, P | 1 |
| Holbrook, NJ; Klotz, LO; Schieke, SM; Sies, H | 1 |
| Deby-Dupont, G; Hans, P; Kohnen, S; Lamy, M; Mathy-Hartert, M; Mouithys-Mickalad, A | 1 |
| Calabro, G; Caputi, AP; Cuzzocrea, S; De Sarro, A; Dugo, L; Mazzon, E; van De LOO, FA | 1 |
| Gilkeson, GS; Keng, T; Privalle, CT; Weinberg, JB | 1 |
| Bachschmid, M; Ullrich, V | 1 |
| Abreu, P; González, MC; Llorente, E; Sánchez, JJ | 1 |
| Liu, P; Quilley, J; Wong, PY; Xu, B | 1 |
| Kato, Y; Osawa, T; Tsuda, T | 1 |
| Arnold, EV; Bohle, DS; Hu, Y | 1 |
| Chen, J; Jin, L; Xian, Y; Xue, J; Ying, X | 1 |
| Daiber, A; Herold, S; Namgaladze, D; Peterson, JA; Schöneich, C; Ullrich, V | 1 |
| Guyton, RA; Katzmark, S; Ma, XL; Nakamura, M; Robinson, J; Ronson, RS; Schmarkey, LS; Thourani, VH; Velez, DA; Vinten-Johansen, J; Wang, NP; Zhao, ZQ | 1 |
| Jasin, HE; Uesugi, M; Yoshida, K | 1 |
| Coddington, JW; Hurst, JK; Khairutdinov, RF | 1 |
| Bast, A; Haenen, GR; Paquay, JB; Stender, G; Tijburg, LB; Wiseman, SA | 1 |
| Bothwell, M; Gunther, EC; Yuen, EC | 1 |
| Asagiri, K; Habara, T; Kamada, Y; Kudo, T; Nakatsuka, M; Noguchi, S; Takata, M | 1 |
| Chan, JS; Filep, JG; Zhang, SL; Zouki, C | 1 |
| Ashraf, QM; Delivoria-Papadopoulos, M; Mishra, OP; Zanelli, SA | 1 |
| Berthiaume, J; Elfering, S; Giulivi, C; Gybina, AA; Sarkela, TM | 1 |
| Bailly, F; Bernier, JL; Catteau, JP; Vamecq, J; Zoete, V | 1 |
| Choi, CR; Choi, IY; Chung, JH; Kim, HC; Kim, WK; Ko, KH; Lee, SJ; Nam, W; Noh, SK; Park, JS; Shin, CY; Shin, DH | 1 |
| Antonello, A; Bonvicini, P; Calò, L; Cantaro, S; D'Angelo, A; Davis, PA; Livi, U; Rigotti, P; Semplicini, A | 1 |
| Aubier, M; Billiar, T; Boczkowski, J; Henin, D; Heymes, C; Lanone, S; Mebazaa, A; Panis, Y; Payen, D; Poderoso, JJ; Zedda, C | 1 |
| Halliwell, B; Ketsawatsakul, U; Whiteman, M | 1 |
| Maguluri, S; Rao, NA; Read, RW; Zhang, J | 1 |
| Bachschmid, M; Erusalimsky, JD; Gygi, D; Kilo, J; Labugger, R; Lüscher, TF; Malinski, T; Palacios-Callender, M; Powell, JM; Quaschning, T; Skepper, JN; Ullrich, V; van der Loo, B | 1 |
| Althaus, JS; Carroll, RT; Fountain, ST; Galatsis, P; Hall, ED; Schmidt, KR; Tseng, MT | 1 |
| Bonham, MP; Bügel, S; Chopra, M; Fairweather-Tait, SJ; Harvey, LJ; Majsak-Newman, G; Mazur, A; McKeown, A; O'Connor, JM; Rayssiguier, Y; Rock, E; Sandström, B; Strain, JJ; Turley, E | 1 |
| Hodges, GR; Ingold, KU; Marwaha, J; Paul, T | 1 |
| Başgut, E; Cakici, I; Hoşgör-Başgut, B; Kanzik, I; Soyak, G; Tunçtan, B | 1 |
| Yamasaki, H | 1 |
| Hooper, DC; Scott, GS | 1 |
| Augusto, O; Bonini, MG | 1 |
| Camhi, SL; Koyama, S; Nelson, DK; Robbins, RA; Sato, E | 1 |
| Chang, YC; Chou, MY; Tai, KW; Tseng, TH | 1 |
| Cantoni, O; Fiorani, M; Guidarelli, A; Tommasini, I | 1 |
| Campos-Pérez, JJ; Ellis, AE; Secombes, CJ | 1 |
| Castro, L; Freeman, BA; Hernandez-Saavedra, D; McCord, JM; Quijano, C; Radi, R | 1 |
| Aston, K; Caputi, AP; Cuzzocrea, S; Dugo, L; Mazzon, E; Riley, DP; Salvemini, D | 1 |
| Ferdinandy, P; Schulz, R | 2 |
| Ali, SF; Cadet, JL; Imam, SZ; Islam, F; Itzhak, Y; Newport, GD; Slikker, W | 1 |
| Ross, GF; Szabó, C; Trapnell, BC; Whitsett, JA; Zsengellér, ZK | 1 |
| Center, DM; Cruikshank, WW; Farber, HW; Fenton, MJ; Klings, ES; Strohmeier, GR; Walsh, JH | 1 |
| Isobe, K; Maruyama, W; Oh-Hashi, K | 1 |
| Buccafusco, JJ; Jonnala, RR | 1 |
| Chen, B; Deen, WM | 1 |
| Cuzzocrea, S; McDonald, MC; Thiemermann, C | 1 |
| Gourdon, I; Guérin, MC; Roch, P; Torreilles, J | 1 |
| Bindoli, A; Boscolo, R; Rigobello, MP; Scutari, G | 1 |
| Caputi, AP; Cuzzocrea, S; Dugo, L; Mazzon, E; Riley, DP; Salvemini, D; Serraino, I | 1 |
| Alvarez, MN; Cayota, A; Naviliat, M; Peluffo, G; Radi, R | 1 |
| Hooper, DC; Koprowski, H; Spitsin, SV | 1 |
| Deby, CM; Deby-Dupont, GP; Henrotin, YE; Lamy, MM; Mouithys-Mickalad, AM; Reginster, JY; Zheng, SX | 1 |
| Ferrini, M; González-Cadavid, NF; Magee, TR; Rajfer, J; Vernet, D | 1 |
| Coddington, JW; Hurst, JK; Wherland, S | 1 |
| Han, S; Kim, YS | 1 |
| Keaney, JF; Price, DT; Vita, JA | 1 |
| Connelly, PW; Crandall, I; Guy, RA; Kain, KC; Maguire, GF | 1 |
| Berry, C; Brosnan, MJ; Dominiczak, AF; Fennell, J; Hamilton, CA | 1 |
| Hada, J; Hayashi, Y; Jiang, MH; Kaku, T; Morimoto, K | 1 |
| Ikota, N; Matsushima, Y; Nakagawa, H; Ozawa, T; Sumiki, E | 1 |
| Kolb-Bachofen, V; Kröncke, KD; Suschek, CV | 1 |
| Bauer, JA; Coyle, CM; Mihm, MJ; Schanbacher, BL; Weinstein, DM | 1 |
| Blanchard, EB; Cudic, M; Ducrocq, C; Servy, C | 1 |
| Freeman, BA; Fukai, T; Harrison, DG; Kurz, S; Laursen, JB; McCann, L; Somers, M; Tarpey, M; Warnholtz, A | 1 |
| Liu, Z; Martin, LJ | 1 |
| Lu, M; Wang, WH; Wei, Y | 1 |
| Katsura, M; Ohkuma, S | 1 |
| Liu, L; Ragan, V; Seidel, ER | 1 |
| Frenzilli, G; Gorbi, S; Nigro, M; Regoli, F; Scarcelli, V | 1 |
| Exner, M; Herold, S; Nauser, T | 1 |
| Feustel, PJ; Kimelberg, HK; Mongin, AA; Osuka, K; Tranmer, BI | 1 |
| Eichert, K; Hamacher, J; Wendel, A; Wunder, MA | 1 |
| Bast, A; Haenen, GR; Heijnen, CG; van Acker, FA; van der Vijgh, WJ | 1 |
| Blanchard, B; Ducrocq, C; Servy, C | 1 |
| Kelpke, S; Reiff, DA; Rue, L; Thompson, JA | 1 |
| Conklin, JL; Kooy, N; Murray, JA; Uc, A | 1 |
| Cheong, YP; Chung, YT; Kim, BR; Kim, MS; Kim, TY; Lee, KM; Oh, J; Park, R; So, HS; Son, Y | 1 |
| Ak, D; Altup, S; Demiryürek, AT; Kanzik , I; Tungel, M | 1 |
| Aktan, AO; Haklar, G; Sayin-Ozveri, E; Yalçin, AS; Yüksel, M | 1 |
| Douglass, LW; Ledbetter, TK; Paape, MJ | 1 |
| Hogg, N; Joseph, J; Kalyanaraman, B; Keefer, LK; Kotamraju, S | 1 |
| Deckel, AW | 1 |
| Epperly, MW; Greenberger, JS; Pearce, LL; Peterson, J; Pitt, BR | 1 |
| Bagchi, D; Horn, T; Keilhoff, G; Roychowdhury, S; Wolf, G | 1 |
| Fertmann, J; Wei, G; Zweier, JL | 1 |
| Brambrink, AM; Golden, WC; Martin, LJ; Traystman, RJ | 1 |
| Barbouti, A; Doulias, PT; Galaris, D; Ischiropoulos, H | 1 |
| de Ruijter-Heijstek, FC; Huisman, A; Rabelink, TJ; Stroes, ES; van Faassen, EE; Vanin, AF | 1 |
| Chaisson, JM; DeWitt, DS; Mathew, BP; Prough, DS | 1 |
| Kitajima, I; Maruyama, I; Nakajima, T; Nakata, M; Sarker, KP | 1 |
| Kissner, R; Koppenol, WH; Merkofer, M; Nauser, T | 1 |
| Fiala, ES; Sodum, RS | 1 |
| Anderson, RL; Bamford, TL; Barker, JE; Guida, E; Konopka, TE; Stewart, AG | 1 |
| Alamillo, JM; García-Olmedo, F | 1 |
| Comhair, SA; Erzurum, SC; Hazen, SL; Kavuru, MS; Klein, DF; Lipscomb, MF; MacPherson, JC; Samoszuk, MK | 1 |
| Alcón, S; Camello, PJ; Hemming, JM; Jennings, L; Mawe, GM; Morales, S; Pozo, MJ | 1 |
| Naem, S; Sadeghi-Hashjin, G | 1 |
| Huang, Z; MacMillan-Crow, L; Thompson, JA; Vickers, SM | 1 |
| Camhi, SL; Hoyt, JC; Nelson, DK; Robbins, RA; Robinson, VK; Sato, E | 1 |
| Ishii, H; Miura, S; Watanabe, N; Zeki, S | 1 |
| Ahmed, Z; Connelly, PW; Draganov, D; Emili, A; Kuksis, A; La Du, BN; Maguire, GF; Ravandi, A | 1 |
| Huang, Q; Huang, X; Jin, C; Liu, J; Yang, GY; Zhao, KS | 1 |
| Cruthirds, DL; Macmillan-Crow, LA | 1 |
| Olsson, LE; Weiss, RM; Wheeler, MA; Yoon, JH | 1 |
| Caputi, AP; Centorrino, T; Ciccolo, A; Cuzzocrea, S; De Sarro, A; Dugo, L; Mazzon, E; Serraino, I | 1 |
| Klatt, P; Lamas, S; López-Muñoz, MJ; Michel, T; Navarro-Antolín, J; Soria, J | 1 |
| Akaike, T; Hayashida, K; Maeda, H; Okamoto, T; Okuyama, A; Wu, J | 1 |
| Kunert, J | 1 |
| Blay, WM; Heintz, NH; Hemenway, DR; Janssen-Heininger, YM; Persinger, RL | 1 |
| Bauer, G; Von Eynatten, K | 1 |
| Banan, A; Fields, JZ; Keshavarzian, A; Zhang, Y | 1 |
| McConnell, P; Merrill, G; Powell, S; Vandyke, K | 1 |
| Caballero, C; López, D; Mitjavila, MT; Puig-Parellada, P; Sánchez, J | 1 |
| Lai, PS; Lin, KT; Linask, KK; Liu, X; Nagele, RG; Sun, FF; Wang, C; Wong, PY; Yin, K; Yue, G | 1 |
| Denker, K; Frölich, JC; Tsikas, D | 1 |
| Filep, JG; József, L; Ouellet, S; Paquette, Y; Zouki, C | 1 |
| Archard, LC; Bevan, AL; Li, Y; Zhang, H | 1 |
| Barry, S; Cantin, AM; Jay-Gerin, JP; Kocsis-Bédard, S; Lemay, R; Paquette, B | 1 |
| Kapoor, S; Naik, DB; Priyadarsini, KI | 1 |
| Cantoni, O; Cellini, B; Dachà, M; De Sanctis, R; Fiorani, M; Guidarelli, A | 1 |
| Arimura, K; Eto, K; Fukuyama, N; Miyamoto, K; Moriguchi, S; Murao, K; Nakanishi, H; Osame, M; Wakamiya, J | 1 |
| Di Stasi, MA; Mallozzi, C; Minetti, M | 1 |
| Berrih-Aknin, S; Gaudry-Talarmain, YM; Moulian, N; Serraf, A; Truffault, F | 1 |
| Groves, JT; Shimanovich, R | 1 |
| Jiao, K; Mandapati, S; Skipper, PL; Tannenbaum, SR; Wishnok, JS | 1 |
| Grisham, MB; Jourd'heuil, D; Jourd'heuil, FL; Kutchukian, PS; Musah, RA; Wink, DA | 1 |
| Brovkovych, S; Brovkovych, V; Dobrucki, I; Dobrucki, LW; Kalinowski, L; Kiechle, F; Malinski, T | 1 |
| Niki, E; Noguchi, N; Satoh, K; Takabe, W; Uchida, K; Yamada, S | 1 |
| Alvarez, B; Radi, R | 1 |
| Cantoni, O; Sestili, P; Tommasini, I | 1 |
| Choi, JW; Kim, H; Kim, W; Ko, KH; Ryu, JH; Ryu, JR; Shin, CY | 1 |
| Diez-Orejas, R; Gil, C; Molero, G; Moro, MA; Nombela, C; Sánchez-Pérez, M | 1 |
| Akaike, T; Maeda, H; Miyamoto, Y; Okamoto, T; Sawa, T; van der Vliet, A | 1 |
| Anderson, PG; Brookes, P; Darley-Usmar, VM; Go, YM; Jo, H; Levonen, AL; Parthasarathy, S; Patel, RP | 1 |
| Heck, DE | 1 |
| Halliwell, B; Spencer, JP; Whiteman, M; Zhao, K | 1 |
| Cakici, I; Karasu , C; Zobali, F | 1 |
| Feix, J; Hogg, N; Joseph, J; Kalyanaraman, B; Zhang, H | 1 |
| Alamillo, JM; Berrocal-Lobo, M; García-Olmedo, F; López-Solanilla, E; Molina, A; Poza-Carrión, C; Rodríguez-Palenzuela, P | 1 |
| Bapat, S; Post, JA; Verkleij, A | 1 |
| Brooks, SS; Combes, A; Feldman, AM; McTiernan, C | 1 |
| Lass, A; Mayer, B; Pfeiffer, S; Schmidt, K | 1 |
| Amano, F; Igimi, S; Tanaka, Y | 1 |
| Bai, P; Bakondi, E; Gergely, P; Gyüre, L; Haskó, G; Hunyadi, J; Szabó, C; Szabó, E; Virág, L | 1 |
| Bhat, VB; Madyastha, KM | 1 |
| Grisham, MB; Kilinc, A; Kilinc, K; Wolf, RE | 1 |
| Gupte, SA; Okada, T | 1 |
| Azadniv, M; Boscia, J; Frampton, MW; Frasier, LM; Speers, DM; Torres, A; Utell, MJ | 1 |
| Fujimura, T; Imai, T; Matsumoto, T; Murayama, K; Taka, H; Uchida, K; Yamakura, F | 1 |
| Bajt, ML; Hinson, JA; Jaeschke, H; Knight, TR; Kurtz, A | 1 |
| Buchczyk, DP; Klotz, LO; Sadik, CD; Schewe, T; Schroeder, P; Sies, H | 1 |
| Haskó, G; Kun, E; Mabley, JG; Rabinovitch, A; Salzman, AL; Suarez-Pinzon, WL; Szabó, C | 1 |
| Herold, S; Matsui, T; Watanabe, Y | 1 |
| Peshenko, IV; Shichi, H | 1 |
| Ali, SF; Cadet, JL; el-Yazal, J; Imam, SZ; Itzhak, Y; Newport, GD; Slikker, W | 1 |
| Bartle, LM; Belzacq, AS; Bernassola, F; Brenner, C; Cohen, I; El Hamel, C; Ferri, KF; Goldmacher, V; Haouzi, D; Jacotot, E; Kroemer, G; Melino, G; Vieira, HL | 1 |
| Gerasimchuk, N; Groves, JT; Hannah, S; Lynch, V; Magda, D; Mody, TD; Sessler, J; Shimanovich, R | 1 |
| Coppey, LJ; Davidson, EP; Dunlap, JA; Gellett, JS; Lund, DD; Yorek, MA | 1 |
| Edelstein, C; Gengaro, P; Lelamali, K; Schrier, RW; Wang, W | 1 |
| Csonka, C; Csont, T; Ferdinandy, P; Onody, A | 1 |
| Brot, N; Erdjument-Bromage, H; Nathan, C; Ruan, J; St John, G; Tempst, P; Weissbach, H | 1 |
| Ferger, B; Halliwell, B; Jenner, P; Rose, S; Themann, C | 1 |
| Fridovich, I; Tarpey, MM | 1 |
| Gauthier, S; Law, A; Quirion, R | 1 |
| Créminon, C; Eligini, S; Habib, A; Lebret, M; Lévy-Toledano, S; Maclouf, J | 1 |
| Aksenova, M; Butterfield, DA; Drake, J; Engman, L; Kanski, J | 1 |
| Schulz, R | 1 |
| Douglas, DJ; Mauk, AG; Stocker, R; Witting, PK | 1 |
| Gupta, MP; Hart, CM; Knepler, JL; Ober, MD; Patterson, C; Pavalko, F; Taher, LN | 1 |
| Arregui, B; Conesa, EL; Fenoy, FJ; López, B; Nadal, JC; Salom, MG; Valero, F | 1 |
| de la Puerta, R; Flavill, JA; Hoult, JR; Martínez Domínguez, ME; Ruíz-Gutíerrez, V | 1 |
| Bekker, JM; Black, SM; Fineman, JR; McMullan, DM; Wedgwood, S | 1 |
| Ali, SF; Imam, SZ; Mayeux, PR; Muldrew, KL; Walker, LM; York, JL | 1 |
| Fukuyama, N; Hayashi, Y; Matsuda, H; Nakazawa, H; Ohtake, S; Sawa, Y | 1 |
| Al-Mustafa, AH; Sies, H; Stahl, W | 1 |
| Ceriello, A; Giugliano, D; Marfella, R; Nappo, F; Quagliaro, L | 1 |
| Hayes, EL; Kanterewicz, BI; Klann, E; Knapp, LT | 1 |
| Gores, GJ; Jaiswal, M; LaRusso, NF; Nakabeppu, Y; Nishioka, N | 1 |
| Cambria, RA; Farooq, MM; Freischlag, JA; Newman, PJ; Seabrook, GR; Serra, A; Towne, JB | 1 |
| Bayne, CJ; Bender, RC; Hahn, UK | 1 |
| Abe, K; Hayashi, T; Manabe, Y; Murakami, T; Shoji, M; Wang, JM; Warita, H | 1 |
| Cantoni, O; Palomba, L; Sestili, P | 1 |
| Blazar, BR; Cornfield, DN; Haddad, IY; Milla, C; Panoskaltsis-Mortari, A; Porter, VA; Yang, S | 1 |
| Baliga, RS; Bauer, JA; Carnes, CA; Chung, MK; Hamlin, RL; Kanderian, A; McCarthy, PM; Nakayama, H; Nakayama, T; Pavia, S; Piao, S; Van Wagoner, DR | 1 |
| Coffey, MJ; Peters-Golden, M; Phare, SM | 1 |
| Ducrocq, C; Gaudry-Talarmain, YM; Guermonprez, L | 1 |
| Chen, Q; Giasson, BI; Ischiropoulos, H; Lee, VM; Norris, EH; Paxinou, E; Rueter, SM; Trojanowski, JQ; Weisse, M | 1 |
| Bauer, G; Steinebach, C | 1 |
| Fukuto, JM; Pan, CJ; Shinyashiki, M; Switzer, CH | 1 |
| Bai, P; Bakondi, E; Gergely, P; Szabó, C; Szabó, E; Virág, L | 1 |
| Lee, JM; Niles, JC; Tannenbaum, SR; Wishnok, JS | 1 |
| Echizenya, M; Hiai, H; Imamura, M; Kondo, S; Onodera, H; Ozeki, M; Tachibana, T; Toyokuni, S; Tsuruyama, T | 1 |
| Augusto, O; Bonini, MG; Mason, RP | 1 |
| Bauer, G; Haberstroh, K; Heigold, S | 1 |
| Ali, SF; Imam, SZ; Mayeux, PR; Zhang, C | 1 |
| Alvarez, S; Boveris, A; Navarro, A | 1 |
| Beisiegel, U; Bräsen, JH; Häkkinen, T; Malle, E; Ylä-Herttuala, S | 1 |
| Armeni, T; Balercia, G; Mantero, F; Principato, G; Regoli, F | 1 |
| Gugliucci, A | 1 |
| August, M; Daiber, A; Kleschyov, AL; Munzel, T; Oelze, M; Sydow, K; Wendt, M; Wieboldt, H | 1 |
| Naseem, KM; Riba, R; Troxler, M | 1 |
| Francisco, JS; Matthews, J; Sinha, A | 1 |
| Kinoshita, N; Mayumi, T; Mizuno, N; Numata, N; Takahashi, K; Utoguchi, N | 1 |
| Goldstein, S; Merenyi, G; Samuni, A | 1 |
| Phipps, J; Sadeghipour, M; Terreux, R | 1 |
| Goldstein, S; Lind, J; Merényi, G | 1 |
| Betteridge, JD; Christopher, S; Dan, Z; Hothersall, J; Jaffar, NZ; Jan, K; John, BD; John, H; Knight, J; Nourooz-Zadeh, J; Sohr, C; Ziegler, D | 1 |
| Kirsch, M; Lehnig, M | 1 |
| Gugliucci, A; Hathuc, C; Hermo, R; Schulze, J | 1 |
| Epperly, MW; Greenberger, EE; Greenberger, JS; Kagan, V; Kanai, AJ; Nie, S; Wegner, R | 1 |
| Etoh, H; Kawagishi, H; Kulkarni, A; Maoka, T; Suzuki, R; Terada, Y; Yomoda, Y | 1 |
| Druhan, LJ; Sun, J; Zweier, JL | 1 |
| Fabron, A; Freedman, J; Kim, RA; Semple, JW; Speck, ER | 1 |
| Corrêa, TC; Di Mascio, P; Martinez, GR; Medeiros, MH; Miyamoto, S; Ronsein, GE | 1 |
| Gupta, D; Harish, B; Kissner, R; Koppenol, WH | 1 |
| Buendía-Atencio, C; González, L; Leyva, V | 1 |
| Bombardieri, M; Hendler, A; Houri-Haddad, Y; Hughes, FJ; Mulli, TK; Nissim, A; Perrett, D; Weiss, EI | 1 |
| Ikawa, S; Kitano, K; Nakashima, Y; Tani, A | 1 |
| Alegria, TG; Augusto, O; Cussiol, JR; de Oliveira, MA; Di Mascio, P; Garratt, RC; Hugo, M; Meireles, DA; Miyamoto, S; Netto, LE; Queiroz, RF; Radi, R; Trujillo, M; Valadares, NF | 1 |
| Bhayana, B; Chiang, LY; Hamblin, MR; Huang, YY; Rajda, PJ; Sarna, T; Szewczyk, G | 1 |
| Ikawa, S; Iwaki, T; Kitano, K; Momoi, Y; Ohshima, T; Tasaki, T; Yamamoto, T | 1 |
| Ikawa, S; Kitano, K; Miyazaki, S; Nakashima, Y; Yokoyama, T | 1 |
| Akagi, H; Ikawa, S; Kitano, K; Miyazaki, S; Yokoyama, T | 1 |
| Chen, Y; He, H; Lei, Z; Wang, S; Zhang, F; Zhang, X | 1 |
| Ikawa, S; Kawabe, H; Kitano, K; Zako, T | 1 |
156 review(s) available for peroxynitric acid and nitrates
| Article | Year |
|---|---|
Nitric oxide: role in neurotoxicity.
Topics: Amino Acid Oxidoreductases; Animals; Calcium; Calmodulin-Binding Proteins; Cell Death; Cells, Cultured; Cerebral Cortex; Diffusion; DNA Damage; Enzyme Activation; Glutamic Acid; Neurons; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Phosphorylation; Poly(ADP-ribose) Polymerases; Receptors, N-Methyl-D-Aspartate; Superoxides | 1995 |
The role of peroxynitrite in nitric oxide-mediated toxicity.
Topics: Animals; Catalysis; Humans; Hydroxyl Radical; Models, Biological; Nitrates; Nitric Oxide; Superoxide Dismutase | 1995 |
Nitric oxide-related oxidants in acute lung injury.
Topics: Acute Disease; Animals; Humans; Lung Diseases; Nitrates; Nitric Oxide; Reactive Oxygen Species | 1995 |
The formation of peroxynitrite in vivo from nitric oxide and superoxide.
Topics: Endothelium, Vascular; Kinetics; Nitrates; Nitric Oxide; Superoxides | 1995 |
The chemistry of peroxynitrite: a product from the reaction of nitric oxide with superoxide.
Topics: Animals; Humans; Hydrogen-Ion Concentration; Hydroxylation; Methionine; Nitrates; Nitric Oxide; Nitroso Compounds; Oxidation-Reduction; Sulfhydryl Compounds; Superoxides; Viscosity | 1995 |
Potential genotoxicity of chronically elevated nitric oxide: a review.
Topics: Animals; Cell Transformation, Neoplastic; Deamination; DNA Adducts; DNA Damage; Humans; Hydroxyl Radical; Infections; Inflammation; Neoplasms; Nitrates; Nitric Oxide; Nitroso Compounds; Oxidation-Reduction; Oxidative Stress; Oxygen; Rats | 1995 |
Peroxynitrite versus hydroxyl radical: the role of nitric oxide in superoxide-dependent cerebral injury.
Topics: Animals; Brain; Brain Injuries; Humans; Hydroxyl Radical; Nitrates; Nitric Oxide; Superoxide Dismutase; Superoxides; Tyrosine | 1994 |
Nitric oxide in the central nervous system.
Topics: Animals; Calcium; Cells, Cultured; Central Nervous System; Cysteine; Neurons; Nitrates; Nitric Oxide; Nitroglycerin; Nitroprusside; Oxidation-Reduction; Oxidative Stress; Receptors, N-Methyl-D-Aspartate; S-Nitrosothiols; Superoxides | 1994 |
Reactions of nitric oxide, superoxide and peroxynitrite with superoxide dismutase in neurodegeneration.
Topics: Amyotrophic Lateral Sclerosis; Animals; Brain Ischemia; Cattle; Glutamic Acid; Humans; Macrophages; Models, Neurological; Molecular Structure; Motor Neurons; Myocardial Ischemia; Nerve Degeneration; Nerve Tissue Proteins; Nitrates; Nitric Oxide; Peripheral Nerve Injuries; Peripheral Nerves; Superoxide Dismutase; Superoxides | 1994 |
Pathological implications of nitric oxide, superoxide and peroxynitrite formation.
Topics: Animals; Ischemia; Macrophages; Nitrates; Nitric Oxide; Superoxide Dismutase; Superoxides | 1993 |
Oxidants in cigarette smoke. Radicals, hydrogen peroxide, peroxynitrate, and peroxynitrite.
Topics: alpha 1-Antitrypsin; Catechols; DNA; DNA Damage; Free Radicals; Humans; Hydrogen Peroxide; Nicotiana; Nitrates; Oxidants; Plants, Toxic; Smoke; Tars | 1993 |
Reactions between nitric oxide, superoxide, and peroxynitrite: footprints of peroxynitrite in vivo.
Topics: Animals; Humans; Nitrates; Nitric Oxide; Superoxides | 1995 |
Chemical biology of nitric oxide: regulation and protective and toxic mechanisms.
Topics: Animals; Cells; Chemical Phenomena; Chemistry, Physical; Cytotoxicity, Immunologic; DNA Damage; Energy Metabolism; Enzyme Inhibitors; Free Radicals; Lipid Peroxidation; Metals; Nitrates; Nitric Oxide; Oxidative Stress; Reactive Oxygen Species | 1996 |
Superoxide anion and endothelial regulation of arterial tone.
Topics: Animals; Arteries; Endothelium, Vascular; Homeostasis; Humans; Models, Cardiovascular; Muscle Tonus; Muscle, Smooth, Vascular; Nitrates; Nitric Oxide; Oxidants; Superoxides; Vascular Diseases | 1996 |
Nitration and hydroxylation of phenolic compounds by peroxynitrite.
Topics: Chromatography, High Pressure Liquid; Hydroxylation; Kinetics; Nitrates; Phenols | 1996 |
Peroxynitrite-dependent tyrosine nitration catalyzed by superoxide dismutase, myeloperoxidase, and horseradish peroxidase.
Topics: Kinetics; Nitrates; Peroxidase; Substrate Specificity; Superoxide Dismutase; Tyrosine | 1996 |
Selecting the most appropriate synthesis of peroxynitrite.
Topics: Methods; Nitrates | 1996 |
Syntheses of peroxynitrite: to go with the flow or on solid grounds?
Topics: Methods; Nitrates | 1996 |
Syntheses of pure tetramethylammonium peroxynitrite.
Topics: Methods; Nitrates; Quaternary Ammonium Compounds | 1996 |
Synthesis of peroxynitrite by azide-ozone reaction.
Topics: Azides; Methods; Nitrates; Ozone | 1996 |
Biphasic synthesis of high concentrations of peroxynitrite using water-insoluble alkyl nitrite and hydrogen peroxide.
Topics: Hydrogen Peroxide; Methods; Nitrates; Nitrites | 1996 |
Predicting physical properties of peroxynitrite by quantum mechanics.
Topics: Models, Molecular; Molecular Structure; Nitrates | 1996 |
Detection of secondary radicals from peroxynitrite-medicated oxidations by electron spin resonance.
Topics: Electron Spin Resonance Spectroscopy; Free Radicals; Nitrates; Oxidation-Reduction | 1996 |
Kinetic analysis of reactivity of peroxynitrite with biomolecules.
Topics: Kinetics; Macromolecular Substances; Nitrates | 1996 |
Distinguishing reactivities of peroxynitrite and hydroxyl radical.
Topics: Hydroxyl Radical; Nitrates; Oxidation-Reduction | 1996 |
Using peroxynitrite as oxidant with low-density lipoprotein.
Topics: Animals; Humans; Lipoproteins, LDL; Nitrates; Oxidation-Reduction | 1996 |
Reaction of peroxynitrite and hydrogen peroxide to produce singlet molecular oxygen (1deltag).
Topics: Hydrogen Peroxide; Nitrates; Oxygen | 1996 |
The importance of superoxide in nitric oxide-dependent toxicity: evidence for peroxynitrite-mediated injury.
Topics: Animals; Humans; Nitrates; Nitric Oxide; Superoxide Dismutase; Superoxides | 1996 |
Distinctive chemistries of no-related species.
Topics: Animals; Humans; Nervous System Diseases; Nitrates; Nitric Oxide; Receptors, N-Methyl-D-Aspartate; Superoxides | 1996 |
The pathophysiological role of peroxynitrite in shock, inflammation, and ischemia-reperfusion injury.
Topics: Animals; Humans; Hydroxyl Radical; Inflammation; Ischemia; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Oxidation-Reduction; Oxidative Stress; Poly(ADP-ribose) Polymerases; Reperfusion Injury; Shock; Superoxides | 1996 |
Nitric oxide synthases.
Topics: Animals; Binding Sites; Calcium; Enzyme Induction; Humans; Isoenzymes; Molecular Structure; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Oxidants | 1996 |
Practical approaches to low density lipoprotein oxidation: whys, wherefores and pitfalls.
Topics: Animals; Azo Compounds; Biochemistry; Chromatography, Ion Exchange; Electrophoresis, Agar Gel; Electrophoresis, Polyacrylamide Gel; Fluorescence; Glucose; Humans; Iron; Lipid Peroxidation; Lipoproteins, LDL; Macrophages; Metals; Nitrates; Oxidation-Reduction; Reproducibility of Results | 1996 |
Ebselen as a glutathione peroxidase mimic and as a scavenger of peroxynitrite.
Topics: Animals; Azoles; Free Radical Scavengers; Glutathione Peroxidase; Humans; Isoindoles; Models, Biological; Nitrates; Organoselenium Compounds | 1997 |
DNA strand breakage and activation of poly-ADP ribosyltransferase: a cytotoxic pathway triggered by peroxynitrite.
Topics: Animals; Apoptosis; Diabetes Mellitus; DNA Damage; Enzyme Activation; Humans; Nitrates; Nitric Oxide; Oxidants; Poly(ADP-ribose) Polymerases | 1996 |
Nitric oxide, superoxide, and peroxynitrite: the good, the bad, and ugly.
Topics: Animals; Arteriosclerosis; Endothelium, Vascular; Humans; Models, Biological; Muscle, Smooth, Vascular; Neurons; Nitrates; Nitric Oxide; Oxyhemoglobins; Second Messenger Systems; Superoxide Dismutase; Superoxides; Synapses | 1996 |
Possible roles of nitric oxide and peroxynitrite in murine leishmaniasis.
Topics: Animals; Anions; Hemoglobins; Leishmania major; Leishmaniasis; Mice; Mice, Inbred BALB C; Nitrates; Nitric Oxide; Oxidants; Reactive Oxygen Species; Superoxides; Tyrosine | 1996 |
Peroxynitrite: mediator of the toxic action of nitric oxide.
Topics: Animals; Humans; Nitrates; Nitric Oxide; Oxidative Stress | 1996 |
Peroxynitrite: a two-faced metabolite of nitric oxide.
Topics: Animals; Apoptosis; Cell Survival; Humans; Nitrates; Nitric Oxide; Signal Transduction | 1997 |
The interplay of nitric oxide and peroxynitrite with signal transduction pathways: implications for disease.
Topics: Animals; Humans; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Oxidants; Oxidation-Reduction; Signal Transduction | 1997 |
gamma-Tocopherol: an efficient protector of lipids against nitric oxide-initiated peroxidative damage.
Topics: Humans; Lipid Peroxidation; Macrophages; Nitrates; Nitric Oxide; Vitamin E | 1997 |
Nitric oxide biochemistry.
Topics: Animals; Brain Diseases; Cell Survival; Disease; Humans; Isoenzymes; Mitochondria; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Oxidants; Oxygen Consumption | 1997 |
Induction of the mitochondrial permeability transition by peroxynitrite.
Topics: Animals; Apoptosis; Electron Transport; Humans; Mitochondria; Models, Biological; Necrosis; Nitrates; Oxidants; Oxidative Stress; Permeability | 1997 |
Role of poly(ADP-ribose) synthetase activation in the suppression of cellular energetics in response to nitric oxide and peroxynitrite.
Topics: Animals; Diabetes Mellitus; DNA Damage; Energy Metabolism; Enzyme Activation; Humans; Hydroxyl Radical; Inflammation; Mitochondria; Models, Biological; Nitrates; Nitric Oxide; Oxidants; Oxygen Consumption; Poly(ADP-ribose) Polymerases; Reperfusion Injury; Shock | 1997 |
Nitric oxide, free radicals and cell signalling in cardiovascular disease.
Topics: Animals; Calcium; Cardiovascular Diseases; Endothelium, Vascular; Free Radicals; Homeostasis; Humans; Models, Cardiovascular; Nitrates; Nitric Oxide; Signal Transduction; Superoxides | 1997 |
Potential mechanisms for nitric oxide-mediated impairment of brain mitochondrial energy metabolism.
Topics: Animals; Astrocytes; Brain; Energy Metabolism; Mitochondria; Models, Neurological; Neurons; Nitrates; Nitric Oxide; Oxidants; Oxygen Consumption; Signal Transduction | 1997 |
Free radicals in viral pathogenesis: molecular mechanisms involving superoxide and NO.
Topics: Animals; Cytokines; Free Radicals; Humans; Hydroxyl Radical; Isoenzymes; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Oxidants; Superoxides; Virus Diseases; Viruses | 1998 |
Biosynthesis and action of nitric oxide in mammalian cells.
Topics: Animals; Biopterins; Calmodulin; Cardiovascular System; Central Nervous System; Cytochrome P-450 Enzyme System; Humans; Immune System; Mammals; Nitrates; Nitric Oxide | 1997 |
DNA damage induced by peroxynitrite: subsequent biological effects.
Topics: Animals; Apoptosis; Cell Transformation, Neoplastic; DNA; DNA Damage; Guanine; Humans; Inflammation; Nitrates; Nitric Oxide; Oxidants; Poly(ADP-ribose) Polymerases; Superoxides | 1997 |
Expression of extracellular SOD and iNOS in macrophages and smooth muscle cells in human and rabbit atherosclerotic lesions: colocalization with epitopes characteristic of oxidized LDL and peroxynitrite-modified proteins.
Topics: Adult; Aged; Animals; Arteriosclerosis; Enzyme Induction; Epitopes; Extracellular Space; Female; Humans; Lipoproteins, LDL; Macrophages; Male; Middle Aged; Muscle, Smooth, Vascular; Nitrates; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Oxidants; Rabbits; Superoxide Dismutase | 1998 |
[Chemistry and biology of peroxynitrite].
Topics: Animals; Carbon Dioxide; DNA; Hydrogen Peroxide; Hydroxylation; Lipid Peroxidation; Nitrates; Nitrosation; Oxidants; Oxidation-Reduction; Sulfhydryl Compounds; Vitamin E | 1998 |
Peroxynitrite: a putative cytotoxin.
Topics: Animals; Arteriosclerosis; Endotoxemia; Humans; Nitrates; Nitric Oxide; Oxidants; Reperfusion Injury; Superoxides | 1998 |
Living and dying with reactive species. Focus on "peroxynitrite induces apoptosis of HL-60 cells by activation of a caspase-3 family protease".
Topics: Apoptosis; Caspase 3; Caspases; Cysteine Endopeptidases; Enzyme Activation; HL-60 Cells; Humans; Nitrates; Oxidants | 1998 |
Pathophysiological chemistry of nitric oxide and its oxygenation by-products.
Topics: Guanylate Cyclase; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrogen Oxides; Oxadiazoles; Quinoxalines; Vasodilation | 1998 |
Role of nitric oxide in endotoxic shock. An overview of recent advances.
Topics: Anti-Inflammatory Agents; Disease Models, Animal; Enzyme Inhibitors; Gene Deletion; Humans; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Prostaglandin-Endoperoxide Synthases; Shock, Septic; Superoxides | 1998 |
Mechanisms of peroxynitrite oxidations and rearrangements: the theoretical perspective.
Topics: Nitrates; Nitric Acid; Oxidants; Oxidation-Reduction; Reactive Oxygen Species | 1998 |
Nitric oxide in the local host reaction to total hip replacement.
Topics: Animals; Cyclooxygenase 2; Foreign-Body Reaction; Hip Prosthesis; Humans; Isoenzymes; Membrane Proteins; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Peroxidases; Prostaglandin-Endoperoxide Synthases; Prosthesis Failure; Superoxides | 1998 |
Peroxynitrite: a biologically significant oxidant.
Topics: Animals; Humans; Nitrates; Nitric Oxide; Oxidants; Oxidative Stress; Reactive Oxygen Species; Superoxides | 1998 |
Nitric oxide and hypercholesterolemia: a matter of oxidation and reduction?
Topics: Animals; Humans; Hypercholesterolemia; Nitrates; Nitric Oxide; Oxidation-Reduction | 1998 |
Neuroprotective versus neurodestructive effects of NO-related species.
Topics: Animals; Central Nervous System; Down-Regulation; Ion Channels; Neurons; Neuroprotective Agents; Neurotoxins; Nitrates; Nitric Oxide; Nitric Oxide Donors; Nitroglycerin; Oxidation-Reduction; Receptors, N-Methyl-D-Aspartate; Superoxides | 1998 |
Role of poly(ADP-ribose) synthetase in inflammation and ischaemia-reperfusion.
Topics: Animals; Cell Death; DNA Damage; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Humans; Inflammation; Nitrates; Oxidants; Oxidative Stress; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Reperfusion Injury | 1998 |
Hydroxyl radicals and nitric oxide in neurotoxicity and neuroprotection.
Topics: Animals; Humans; Hydrogen-Ion Concentration; Hydroxyl Radical; Nervous System; Nervous System Physiological Phenomena; Nitrates; Nitric Oxide | 1998 |
The versatile and complex enzymology of nitric oxide synthase.
Topics: Animals; Biopterins; Calcium; Dimerization; Humans; Nitrates; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Oxidation-Reduction; Protein Conformation | 1998 |
Nitric oxide and oxygen radicals in infection, inflammation, and cancer.
Topics: Animals; Bacterial Infections; Free Radicals; Humans; Infections; Inflammation; Mice; Neoplasms; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Reactive Oxygen Species; Superoxides; Virus Diseases | 1998 |
Nitric oxide and low-density lipoprotein oxidation.
Topics: Animals; Cardiovascular Diseases; Humans; Lipoproteins, LDL; Nitrates; Nitric Oxide; Oxidation-Reduction | 1998 |
The basic chemistry of nitrogen monoxide and peroxynitrite.
Topics: Chemical Phenomena; Chemistry, Physical; Diffusion; Nitrates; Nitric Oxide; Oxidation-Reduction; Solubility; Superoxide Dismutase; Thermodynamics | 1998 |
Oxidative chemistry of nitric oxide: the roles of superoxide, peroxynitrite, and carbon dioxide.
Topics: Carbon Dioxide; Free Radical Scavengers; Free Radicals; Nitrates; Nitric Oxide; Oxidation-Reduction; Superoxides | 1998 |
Nitric oxide and its congeners in mitochondria: implications for apoptosis.
Topics: Animals; Apoptosis; Calcium; Electron Transport Complex IV; Genes, bcl-2; Humans; Mitochondria; NAD; Nitrates; Nitric Oxide; Reactive Oxygen Species | 1998 |
Nitric oxide as an inflammatory mediator in autoimmune MRL-lpr/lpr mice.
Topics: Animals; Arthritis; Autoimmune Diseases; Autoimmunity; Disease Models, Animal; Humans; Inflammation; Inflammation Mediators; Mice; Mice, Inbred MRL lpr; Mice, Knockout; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Phagocytes; Rats | 1998 |
Nitric oxide and peroxynitrite production in ocular inflammation.
Topics: Animals; Disease Models, Animal; Eye; Humans; Inflammation Mediators; Mice; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Rabbits; Rats; Uveitis | 1998 |
Contribution of reactive oxygen and nitrogen species to particulate-induced lung injury.
Topics: Animals; Asbestos; Gene Expression; Humans; Lung; Lung Injury; Nitrates; Nitric Oxide; Nitrogen; Reactive Oxygen Species; Sulfhydryl Compounds | 1998 |
[Superoxide, nitric oxide and peroxynitrite].
Topics: Aged; Aged, 80 and over; Animals; Female; Humans; Male; Nitrates; Nitric Oxide; Oxidants; Superoxide Dismutase; Superoxides | 1998 |
The nonspecific inflammatory response to injury.
Topics: Cell Adhesion Molecules; Cytokines; Endothelium, Vascular; Free Radical Scavengers; Humans; Inflammation; Inflammation Mediators; Neutrophil Activation; Neutrophils; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Oxidants; Reactive Oxygen Species; Superoxides; Surgical Procedures, Operative; Tumor Necrosis Factor-alpha; Up-Regulation | 1998 |
Role of superoxide dismutase in ischemic brain injury: a study using SOD-1 transgenic mice.
Topics: Animals; Brain; Brain Ischemia; Cerebral Infarction; Cerebrovascular Circulation; Humans; Mice; Mice, Transgenic; Nitrates; Nitric Oxide; Superoxide Dismutase; Superoxides | 1998 |
Nitric oxide and circulatory shock.
Topics: Animals; Humans; Microcirculation; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Shock; Shock, Hemorrhagic; Shock, Septic | 1998 |
Direct and simultaneous ultraviolet second-derivative spectrophotometric determination of nitrite and nitrate in preparations of peroxynitrite.
Topics: Animals; Humans; Nitrates; Nitrites; Spectrophotometry, Ultraviolet | 1999 |
Nitric oxide donor generation from reactions of peroxynitrite.
Topics: Animals; Humans; Nitrates; Nitric Oxide; Nitric Oxide Donors | 1999 |
Defenses against peroxynitrite.
Topics: Animals; Antioxidants; Glutathione Peroxidase; Humans; Nitrates; Nitric Oxide; Oxidants; Selenium Compounds | 1999 |
Assessment of peroxynitrite scavengers in vitro.
Topics: Animals; Biological Assay; Free Radical Scavengers; Humans; Nitrates; Nitric Oxide | 1999 |
Peroxynitrite studied by stopped-flow spectroscopy.
Topics: Animals; Humans; Nitrates; Oxidants; Spectrum Analysis | 1999 |
Peroxynitrite reactions with carbon dioxide-bicarbonate.
Topics: Animals; Bicarbonates; Carbon Dioxide; Free Radicals; Humans; Nitrates | 1999 |
Examining apoptosis in cultured cells after exposure to nitric oxide and peroxynitrite.
Topics: Animals; Apoptosis; Cells, Cultured; Humans; Nitrates; Nitric Oxide; Nitric Oxide Donors; Oxidants | 1999 |
Nitration of unsaturated fatty acids by nitric oxide-derived reactive species.
Topics: Animals; Chromatography, High Pressure Liquid; Fatty Acids, Unsaturated; Free Radicals; Humans; Lipid Peroxidation; Nitrates; Nitric Oxide; Nitrogen Dioxide; Nitrous Acid | 1999 |
Products from reaction of peroxynitrite with gamma-tocopherol.
Topics: Animals; Chromatography, High Pressure Liquid; Gas Chromatography-Mass Spectrometry; Humans; Liposomes; Nitrates; Oxidants; Oxidation-Reduction; Vitamin E | 1999 |
Nitric oxide in neurodegeneration.
Topics: AIDS Dementia Complex; Animals; Cerebrovascular Disorders; Humans; Neurodegenerative Diseases; Neurons; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Parkinson Disease | 1998 |
Role of endogenous nitric oxide and peroxynitrite formation in the survival and death of motor neurons in culture.
Topics: Amyotrophic Lateral Sclerosis; Animals; Apoptosis; Brain-Derived Neurotrophic Factor; Cell Death; Cell Survival; Humans; Motor Neurons; Nitrates; Nitric Oxide; Superoxide Dismutase; Tyrosine | 1998 |
Oxidative stress in bacterial meningitis.
Topics: Animals; Brain Injuries; Host-Parasite Interactions; Humans; Lipid Peroxidation; Meningitis, Bacterial; Nitrates; Nitric Oxide; Oxidants; Oxidative Stress; Poly(ADP-ribose) Polymerases; Reactive Oxygen Species | 1999 |
Demyelination: the role of reactive oxygen and nitrogen species.
Topics: Animals; Antioxidants; Demyelinating Diseases; Humans; Inflammation; Lipid Peroxidation; Nervous System; Nitrates; Nitric Oxide; Oxidants; Oxidative Stress; Reactive Oxygen Species | 1999 |
Peroxynitrite in airway diseases.
Topics: Animals; Asthma; Bronchial Hyperreactivity; Humans; Lung; Lung Diseases; Macrophages, Alveolar; Nitrates; Rats | 1998 |
The chemistry of DNA damage from nitric oxide and peroxynitrite.
Topics: Animals; DNA Damage; Free Radical Scavengers; Humans; Nitrates; Nitric Oxide; Oxidants; Oxidation-Reduction; Oxidative Stress | 1999 |
Reactions of prostaglandin endoperoxide synthase with nitric oxide and peroxynitrite.
Topics: Animals; Cyclooxygenase Inhibitors; Enzyme Activation; Nitrates; Nitric Oxide; Peptide Mapping; Prostaglandins | 1999 |
Nitric oxide, mitochondria and neurological disease.
Topics: Amyotrophic Lateral Sclerosis; Astrocytes; Cell Death; Electron Transport; Glutamic Acid; Humans; Mitochondria; Nervous System Diseases; Neurodegenerative Diseases; Neurons; Nitrates; Nitric Oxide; Permeability | 1999 |
Chemistry of peroxynitrite and its relevance to biological systems.
Topics: Animals; Humans; Nitrates; Oxidants; Superoxide Dismutase; Thermodynamics | 1999 |
Protection against peroxynitrite.
Topics: Animals; Humans; Molecular Structure; Nitrates; Oxidants | 1999 |
Nitric Oxide. III. A molecular prelude to intestinal inflammation.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Biomarkers; Female; Humans; Inflammation; Intestinal Mucosa; Intestines; Models, Biological; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrogen Oxides; Pregnancy | 1999 |
Nitration modifying function of proteins, hormones and neurotransmitters.
Topics: Animals; Homeostasis; Hormones; Humans; Neurotransmitter Agents; Nitrates; Nitric Oxide; Oxidants; Oxidative Stress; Proteins; Tetranitromethane; Tyrosine | 1999 |
Peroxynitrite: reactive, invasive and enigmatic.
Topics: Cell Membrane Permeability; Free Radical Scavengers; Mitochondria; Nitrates; Tyrosine | 1999 |
Nitric oxide and apoptosis.
Topics: Animals; Apoptosis; Cardiovascular System; Central Nervous System; Humans; Immunity; Nitrates; Nitric Oxide | 1999 |
Nitric oxide and mitochondrial respiration.
Topics: Animals; Apoptosis; Electron Transport Complex IV; Energy Metabolism; Enzyme Induction; Humans; Mitochondria; Models, Chemical; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II | 1999 |
Biological aspects of reactive nitrogen species.
Topics: Animals; Apoptosis; Inflammation; Lipoproteins; Membranes; Nitrates; Nitric Oxide; Nitric Oxide Donors; Nitrogen; Oxidation-Reduction; Signal Transduction; Tyrosine; Vasodilation | 1999 |
Roles of nitric oxide in brain hypoxia-ischemia.
Topics: Animals; Brain; Brain Ischemia; Excitatory Amino Acids; Humans; Hypoxia, Brain; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type III; Perinatology; Vasodilation | 1999 |
Peroxynitrite inactivates prostacyclin synthase by heme-thiolate-catalyzed tyrosine nitration.
Topics: Animals; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Epoprostenol; Heme; Humans; Intramolecular Oxidoreductases; Nitrates; Nitric Oxide; Sulfhydryl Compounds; Superoxides; Tyrosine; Vascular Resistance | 1999 |
Nitric Oxide. V. therapeutic potential of nitric oxide donors and inhibitors.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Drug Therapy, Combination; Enzyme Inhibitors; Free Radical Scavengers; Gastrointestinal Diseases; Humans; Nitrates; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Protein Isoforms | 1999 |
Effects of nitric oxide and nitric oxide-derived species on prostaglandin endoperoxide synthase and prostaglandin biosynthesis.
Topics: Animals; Enzyme Activation; Nitrates; Nitric Oxide; Prostaglandin-Endoperoxide Synthases; Prostaglandins | 1999 |
Antioxidant actions of plant foods: use of oxidative DNA damage as a tool for studying antioxidant efficacy.
Topics: Antioxidants; Copper; DNA Adducts; DNA Damage; Nitrates; Oxidative Stress; Phenanthrolines; Plants, Edible | 1999 |
Interactions of nitric oxide with hemoproteins: roles of nitric oxide in mitochondria.
Topics: Animals; Electron Transport Complex IV; Guanylate Cyclase; Hemeproteins; Hemoglobins; Humans; Mitochondria; Nitrates; Nitric Oxide; Oxidation-Reduction; Oxygen; Rats; Rats, Wistar; Superoxides | 1999 |
Peroxynitrite: an endogenous oxidizing and nitrating agent.
Topics: Amino Acids; Animals; Antioxidants; Bicarbonates; Carbon Dioxide; DNA; DNA Damage; Hemeproteins; Humans; Hydroxylation; Nitrates; Nitric Oxide; Oxidation-Reduction; Porphyrins; Sulfhydryl Compounds; Superoxides | 1999 |
[Active nitrogen species. A new research area for pharmaceutical chemistry].
Topics: Enzyme Inhibitors; Free Radical Scavengers; Free Radicals; Humans; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrogen; Reactive Oxygen Species | 1999 |
Nitrosative and oxidative modulation of iron regulatory proteins.
Topics: Animals; Cysteine; Cytokines; Gene Expression Regulation; Iron; Iron Regulatory Protein 1; Iron Regulatory Protein 2; Iron-Regulatory Proteins; Iron-Sulfur Proteins; Mice; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Oxidation-Reduction; Oxidative Stress; Protein Processing, Post-Translational; Rats; Reactive Oxygen Species; Regulatory Sequences, Nucleic Acid; RNA-Binding Proteins; RNA, Messenger | 1999 |
Nitric oxide: a radical molecule in quest of free radicals in proteins.
Topics: Amino Acids; Animals; Arachidonic Acid; Bacterial Proteins; Binding Sites; Free Radicals; Humans; Iron; Mice; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Peroxidase; Photosynthetic Reaction Center Complex Proteins; Photosystem II Protein Complex; Prostaglandin-Endoperoxide Synthases; Proteins; Tyrosine | 1999 |
Potent neuroprotectants linked to bifunctional inhibition.
Topics: Animals; Brain; Brain Ischemia; Enzyme Inhibitors; Free Radical Scavengers; Mice; Models, Biological; Neuroprotective Agents; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Pyrazines; Rats; Thiophenes | 1999 |
Neurodegenerative disorders: the role of peroxynitrite.
Topics: Alzheimer Disease; Animals; Central Nervous System; Humans; Inflammation; Motor Neuron Disease; Multiple Sclerosis; Neurodegenerative Diseases; Neurons; Nitrates; Oxidants; Parkinson Disease | 1999 |
Kallikrein-kinin in infection and cancer.
Topics: alpha 1-Antitrypsin; Animals; Bacterial Infections; Capillary Permeability; Collagenases; Enzyme Precursors; Humans; Kallikrein-Kinin System; Metalloendopeptidases; Neoplasms; Nitrates; Nitric Oxide | 1999 |
Mechanisms of DNA oxidation.
Topics: Animals; DNA; DNA Damage; Humans; Hydroxyl Radical; Neoplasms; Nitrates; Oxidation-Reduction | 1999 |
The cardiovascular effects and implications of peroxynitrite.
Topics: Animals; Arteriosclerosis; Endothelium, Vascular; Humans; Myocardial Reperfusion Injury; Myocardium; Nitrates; Nitric Oxide | 1999 |
Reactions of *NO, *NO2 and peroxynitrite in membranes: physiological implications.
Topics: Animals; Cell Membrane; Free Radicals; Humans; Lipoproteins, LDL; Metals; Nitrates; Nitric Oxide; Nitrogen Dioxide; Oxidation-Reduction | 1999 |
Nitric oxide and peroxynitrite. The ugly, the uglier and the not so good: a personal view of recent controversies.
Topics: Animals; Biomarkers; Disease; Humans; Nitrates; Nitric Oxide; Superoxides; Tyrosine | 1999 |
Neuroprotective properties of nitric oxide.
Topics: Animals; Free Radical Scavengers; Glutathione; Humans; Nitrates; Nitric Oxide; Nitric Oxide Donors; Nitroso Compounds; Oxidants; Oxidative Stress; Reactive Oxygen Species; S-Nitrosoglutathione | 1999 |
Peroxynitrite and inflammatory bowel disease.
Topics: Free Radicals; Humans; Inflammatory Bowel Diseases; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Reactive Oxygen Species | 2000 |
Nitric oxide and peroxynitrite in the perinatal period.
Topics: Animals; Female; Humans; Infant, Newborn; Nitrates; Nitric Oxide; Oxidants | 2000 |
Essential fatty acids and related molecular and cellular mechanisms in multiple sclerosis: new looks at old concepts.
Topics: Animals; Apoptosis; Autoimmune Diseases; Demyelinating Diseases; Dietary Fats; Double-Blind Method; Encephalomyelitis, Autoimmune, Experimental; Fatty Acids, Essential; Fatty Acids, Unsaturated; Humans; Lipid Peroxidation; Membrane Lipids; Multiple Sclerosis; Myelin Sheath; Nitrates; Nitric Oxide; Oxidative Stress; Signal Transduction; Venules | 1999 |
[Progress on physiopathological study of shock--Approach from the molecular biological point of view].
Topics: Adrenomedullin; Apoptosis; Gene Expression; Heat-Shock Response; Humans; Isoenzymes; Myocardial Depressant Factor; NF-kappa B; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Peptides; Shock | 1999 |
Superoxide and iron: partners in crime.
Topics: Escherichia coli; Gene Deletion; Homeostasis; Hydrogen Peroxide; Iron; Nitrates; Superoxide Dismutase; Superoxides | 1999 |
Biology of nitric oxide signaling.
Topics: Drug Interactions; Free Radical Scavengers; Homeostasis; Humans; Nitrates; Nitric Oxide; Nitrosation; Oxidants; Signal Transduction | 2000 |
Nitric oxide and interstitial lung disease.
Topics: Anti-Inflammatory Agents; Free Radical Scavengers; Humans; Lung; Lung Diseases, Interstitial; Nitrates; Nitric Oxide; Oxidants; Superoxides | 1998 |
Mutations induced by reactive nitrogen oxide species in the supF forward mutation assay.
Topics: DNA Damage; DNA, Bacterial; Escherichia coli; Genes, Suppressor; Humans; Mutation; Nitrates; Nitric Oxide; RNA, Transfer | 2000 |
Free radicals and antioxidants in the year 2000. A historical look to the future.
Topics: Animals; Antioxidants; Escherichia coli; Ferrous Compounds; Free Radicals; Humans; Mice; Mice, Knockout; Nitrates; Nitric Oxide | 2000 |
Protein oxidation.
Topics: Antioxidants; Catalysis; Nitrates; Oxidation-Reduction; Proteins; Reactive Oxygen Species | 2000 |
Nitric oxide regulation of free radical- and enzyme-mediated lipid and lipoprotein oxidation.
Topics: Animals; Arteriosclerosis; Endothelium, Vascular; Free Radicals; Humans; Lipid Metabolism; Lipoproteins; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Oxidation-Reduction | 2000 |
Calcium signaling and oxidant stress in the vasculature.
Topics: Blood Vessels; Calcium Signaling; Catalase; Endothelium, Vascular; Free Radicals; Humans; Ion Transport; Muscle, Smooth, Vascular; Nitrates; Nitric Oxide; Oxidative Stress; Peroxides; Reactive Oxygen Species; Superoxide Dismutase; Superoxides; Vascular Resistance | 2000 |
Interaction of peroxynitrite with selenoproteins and glutathione peroxidase mimics.
Topics: Antioxidants; Azoles; Free Radicals; Glutathione Peroxidase; Humans; Isoindoles; Nitrates; Organoselenium Compounds; Oxidants; Oxidative Stress; Proteins; Selenocysteine; Selenomethionine; Selenoprotein P; Selenoproteins; Tellurium; Thioredoxin-Disulfide Reductase | 2000 |
Peroxynitrite scavenging by metalloporphyrins and thiolates.
Topics: Animals; Cell Death; Free Radical Scavengers; Humans; In Vitro Techniques; Metalloporphyrins; Nitrates; Oxidation-Reduction; Sulfhydryl Compounds | 2000 |
Nitric oxide, peroxynitrite, and lower respiratory tract inflammation.
Topics: Animals; Asthma; Bronchoalveolar Lavage Fluid; Cystic Fibrosis; Eosinophils; Humans; Nitrates; Nitric Oxide; Pneumonia; Tyrosine | 2000 |
Mechanisms of the pro- and anti-oxidant actions of nitric oxide in atherosclerosis.
Topics: Animals; Antioxidants; Arteriosclerosis; Endothelium, Vascular; Free Radical Scavengers; Free Radicals; Glutathione; Humans; Lipid Metabolism; Lipid Peroxidation; Lipoxygenase; Muscle, Smooth, Vascular; Nitrates; Nitric Oxide; Signal Transduction; Vitamin E | 2000 |
Oxidants, nitric oxide and prostanoids in the developing ocular vasculature: a basis for ischemic retinopathy.
Topics: Choroid; Dinoprost; Endothelial Growth Factors; Free Radicals; Humans; Infant, Newborn; Infant, Premature; Ischemia; Lipid Peroxidation; Lymphokines; Neovascularization, Pathologic; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Oxidative Stress; Oxygen; Receptors, Prostaglandin E; Retina; Retinal Vessels; Retinopathy of Prematurity; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors | 2000 |
Nitric oxide and intestinal inflammation.
Topics: Antioxidants; Enteritis; Free Radical Scavengers; Homeostasis; Humans; Inflammatory Bowel Diseases; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Oxidants; Protective Agents; Sepsis | 2000 |
Nitric oxide, cytochrome c and mitochondria.
Topics: Animals; Catalase; Cytochrome c Group; Electron Transport; Electron Transport Complex IV; Mitochondria; Nitrates; Nitric Oxide; Reactive Oxygen Species; Superoxide Dismutase | 1999 |
Effects of nitric oxide and peroxynitrite on the cytochrome oxidase K(m) for oxygen: implications for mitochondrial pathology.
Topics: Animals; Bacteria; Cell Hypoxia; Electron Transport Complex IV; Enzyme Activation; Humans; Mitochondria; Nitrates; Nitric Oxide; Oxygen; Oxygen Consumption | 2000 |
Nitric oxide reactivity and mechanisms involved in its biological effects.
Topics: Animals; Guanylate Cyclase; Hemoglobins; Humans; Nitrates; Nitric Oxide; Poly(ADP-ribose) Polymerases; Sulfhydryl Compounds; Vasodilation | 2000 |
Superoxide as a messenger of endothelial function.
Topics: Animals; Endothelium; Humans; Models, Biological; Models, Chemical; Nitrates; Nitric Oxide; Oxidation-Reduction; Reactive Oxygen Species; Superoxides | 2000 |
Nitrite-dependent nitric oxide production pathway: implications for involvement of active nitrogen species in photoinhibition in vivo.
Topics: Animals; Humans; Nitrate Reductase; Nitrate Reductases; Nitrates; Nitric Oxide; Nitrites; Photosynthesis; Plant Physiological Phenomena | 2000 |
Unraveling peroxynitrite formation in biological systems.
Topics: Animals; Carbon Dioxide; Cytochrome c Group; Electron Spin Resonance Spectroscopy; Fluorescent Dyes; Free Radicals; Humans; Hydroxylation; Immunohistochemistry; Indicators and Reagents; Luminescent Measurements; Nitrates; Oxidants; Oxidative Stress; Phenols; Tyrosine | 2001 |
Redox control of vascular nitric oxide bioavailability.
Topics: Animals; Antioxidants; Biological Availability; Blood Vessels; Catalase; Glutathione Peroxidase; Humans; Lipid Peroxidation; Nitrates; Nitric Oxide; Oxidation-Reduction; Oxidative Stress; Solubility; Superoxide Dismutase; Superoxides; Vascular Diseases | 2000 |
Oxidative stress and vascular damage in hypertension.
Topics: Adrenergic beta-Antagonists; Angiotensin II; Animals; Blood Vessels; Cardiovascular Diseases; Disease Models, Animal; Estrogens; Gene Transfer Techniques; Humans; Hydrogen Peroxide; Hypertension; Mitochondria; NADH, NADPH Oxidoreductases; NADPH Oxidases; Nitrates; Nitric Oxide Synthase; Oxidative Stress; Rats; Reactive Oxygen Species; Renin-Angiotensin System; Risk Factors; Signal Transduction; Superoxide Dismutase; Vitamins; Xanthine Oxidase | 2001 |
Implications of inducible nitric oxide synthase expression and enzyme activity.
Topics: Apoptosis; Humans; Inflammation; Models, Biological; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Oxidation-Reduction; Oxidative Stress; Signal Transduction; Transcription, Genetic | 2000 |
[Intervention by nitric oxide, NO, and its oxide derivatives particularly in mammals].
Topics: Animals; Humans; Mammals; Nitrates; Nitric Oxide; Protein Processing, Post-Translational; Superoxides; Tyrosine | 2001 |
Nitric oxide and peroxynitrite as factors to stimulate neurotransmitter release in the CNS.
Topics: Animals; Central Nervous System; Humans; Neurotransmitter Agents; Nitrates; Nitric Oxide; Synapses; Synaptic Transmission | 2001 |
Nitric oxide and nitric oxide synthase in Huntington's disease.
Topics: Animals; Apoptosis; Arginine; Calmodulin; Caspases; Cerebrovascular Circulation; CREB-Binding Protein; Enzyme Activation; Enzyme Induction; Forecasting; Glutamic Acid; Humans; Huntington Disease; Mice; Mice, Transgenic; Mitochondria; Models, Animal; Models, Neurological; Nerve Tissue Proteins; Neurons; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nuclear Proteins; Oxidative Stress; Proto-Oncogene Proteins p21(ras); RNA, Messenger; Trans-Activators | 2001 |
Invited review: manganese superoxide dismutase in disease.
Topics: Animals; Apoptosis; Humans; Mice; Mice, Knockout; Mitochondria; Neoplasms; Nitrates; Organ Transplantation; Reactive Oxygen Species; Reperfusion Injury; Superoxide Dismutase; Superoxides | 2001 |
Mechanisms of cell signaling by nitric oxide and peroxynitrite: from mitochondria to MAP kinases.
Topics: Animals; Mitochondria; Mitogen-Activated Protein Kinases; Nitrates; Nitric Oxide; Oxidation-Reduction; Signal Transduction | 2001 |
*NO, RSNO, ONOO-, NO+, *NOO, NOx--dynamic regulation of oxidant scavenging, nitric oxide stores, and cyclic GMP-independent cell signaling.
Topics: Animals; Cyclic GMP; Free Radical Scavengers; Humans; Nitrates; Nitric Oxide; Signal Transduction | 2001 |
Antibiotic activities of peptides, hydrogen peroxide and peroxynitrite in plant defence.
Topics: Anti-Bacterial Agents; Bacterial Physiological Phenomena; Defensins; Hydrogen Peroxide; Nitrates; Oxidants; Plant Leaves; Plant Physiological Phenomena; Plants; Pseudomonas; Uric Acid | 2001 |
NAD(P)H, a directly operating antioxidant?
Topics: Animals; Antioxidants; Cytosol; Forecasting; Free Radical Scavengers; Free Radicals; Humans; Mitochondria; NADP; Nitrates | 2001 |
Methamphetamine-induced dopaminergic neurotoxicity: role of peroxynitrite and neuroprotective role of antioxidants and peroxynitrite decomposition catalysts.
Topics: Animals; Antioxidants; Biomarkers; Dopamine; Dopamine Agents; Enzyme Inhibitors; Humans; Indazoles; Methamphetamine; Nitrates; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; PC12 Cells; Rats; Tyrosine | 2001 |
Methods of detection of vascular reactive species: nitric oxide, superoxide, hydrogen peroxide, and peroxynitrite.
Topics: Blood Vessels; Electrochemistry; Free Radicals; Hydrogen Peroxide; Nitrates; Nitric Oxide; Oxidation-Reduction; Superoxides | 2001 |
The role of mitochondrial nitric oxide synthase in inflammation and septic shock.
Topics: Animals; Humans; Inflammation; Lipopolysaccharides; Mitochondria; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Oxidative Stress; Rats; Reactive Oxygen Species; Shock, Septic | 2002 |
Chemistry of peroxynitrites as compared to peroxynitrates.
Topics: Free Radical Scavengers; Nitrates; Nitrites; Organometallic Compounds; Peroxynitrous Acid | 2005 |
7 trial(s) available for peroxynitric acid and nitrates
| Article | Year |
|---|---|
Oxidation and antioxidation of human low-density lipoprotein and plasma exposed to 3-morpholinosydnonimine and reagent peroxynitrite.
Topics: Adenosine Triphosphatases; Adult; Antioxidants; Enzyme Inhibitors; Female; Humans; Lipoproteins, LDL; Male; Mass Spectrometry; Molsidomine; Nitrates; Oxidants; Oxidation-Reduction; Plasma; Ubiquinone; Vitamin E | 1998 |
Increased formation of the potent oxidant peroxynitrite in the airways of asthmatic patients is associated with induction of nitric oxide synthase: effect of inhaled glucocorticoid.
Topics: Administration, Inhalation; Adult; Asthma; Bronchi; Bronchodilator Agents; Budesonide; Cross-Over Studies; Double-Blind Method; Enzyme Induction; Female; Glucocorticoids; Humans; Male; Nitrates; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Oxidants | 1998 |
Increase in oxidized NO products and reduction in oxidized glutathione in cerebrospinal fluid from patients with sporadic form of amyotrophic lateral sclerosis.
Topics: Aged; Amyotrophic Lateral Sclerosis; Female; Free Radical Scavengers; Glutathione; Humans; Male; Middle Aged; Nitrates; Nitric Oxide; Oxidants; Oxidation-Reduction; Superoxides | 1999 |
Atorvastatin increases ecNOS levels in human platelets of hyperlipidemic subjects.
Topics: Adult; Aged; Anticholesteremic Agents; Atorvastatin; Blood Platelets; Blood Proteins; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Cross-Over Studies; Double-Blind Method; Enzyme Induction; Female; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Hypertriglyceridemia; Male; Middle Aged; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Oxidation-Reduction; Pyrroles; Treatment Outcome; Triglycerides; Tyrosine; Vasodilation | 1999 |
Idiopathic hypercalciuria: O2(-)NO relationship and altered bone metabolism.
Topics: Adult; Bone and Bones; Bone Density; Calcium; Diet; Female; Free Radicals; Humans; Male; Metal Metabolism, Inborn Errors; Middle Aged; Monocytes; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Oxidants; Reverse Transcriptase Polymerase Chain Reaction; RNA; Superoxides | 2000 |
Copper supplementation in humans does not affect the susceptibility of low density lipoprotein to in vitro induced oxidation (FOODCUE project).
Topics: Adult; Copper; Denmark; Diet; Dietary Supplements; England; Female; France; Free Radicals; Humans; Lipid Peroxidation; Lipoproteins, LDL; Male; Middle Aged; Nitrates; Northern Ireland | 2000 |
Ascorbate attenuates atrial pacing-induced peroxynitrite formation and electrical remodeling and decreases the incidence of postoperative atrial fibrillation.
Topics: Aged; Animals; Antioxidants; Ascorbic Acid; Atrial Fibrillation; Cardiac Pacing, Artificial; Coronary Artery Bypass; Dogs; Electrophysiology; Female; Heart Atria; Humans; Male; Middle Aged; Multivariate Analysis; Nitrates; Time Factors; Treatment Outcome; Tyrosine | 2001 |
1166 other study(ies) available for peroxynitric acid and nitrates
| Article | Year |
|---|---|
Free radical yields from the homolysis of peroxynitrous acid.
Topics: Benzothiazoles; Free Radicals; Hydrogen-Ion Concentration; Indicators and Reagents; Kinetics; Nitrates; Nitric Oxide; Sulfonic Acids; Superoxides | 1992 |
Peroxynitrite formation from macrophage-derived nitric oxide.
Topics: Animals; Cattle; Erythrocytes; Kinetics; Macrophages, Alveolar; Nitrates; Nitric Oxide; Oxygen Consumption; Rats; Rats, Sprague-Dawley; Superoxide Dismutase; Superoxides; Tetradecanoylphorbol Acetate | 1992 |
Role of nitric oxide in the oxidant stress during ischemia/reperfusion injury of the liver.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Kupffer Cells; Liver; Male; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Nitroarginine; Oxidants; Rats; Rats, Inbred F344; Reperfusion Injury; Stress, Physiological; Superoxides | 1992 |
Peroxynitrite-mediated tyrosine nitration catalyzed by superoxide dismutase.
Topics: Animals; Binding Sites; Cattle; Erythrocytes; Hydrogen-Ion Concentration; Kinetics; Lasers; Nitrates; Nitric Oxide; Protein Conformation; Spectrum Analysis, Raman; Superoxide Dismutase; Tyrosine | 1992 |
Kinetics of superoxide dismutase- and iron-catalyzed nitration of phenolics by peroxynitrite.
Topics: Animals; Cattle; Edetic Acid; Erythrocytes; Hydrogen-Ion Concentration; Iron; Kinetics; Nitrates; Phenols; Substrate Specificity; Superoxide Dismutase; Thermodynamics | 1992 |
Bactericidal activity of peroxynitrite.
Topics: Anti-Bacterial Agents; Benzoates; Benzoic Acid; Dimethyl Sulfoxide; Escherichia coli; Ethanol; Free Radical Scavengers; Hydrogen-Ion Concentration; Kinetics; Luminescent Measurements; Mannitol; Nitrates; Nitrogen Dioxide | 1992 |
Crystal structure of peroxynitrite-modified bovine Cu,Zn superoxide dismutase.
Topics: Animals; Binding Sites; Cattle; Computer Graphics; Crystallography; Glutamates; In Vitro Techniques; Models, Molecular; Nitrates; Nitrites; Protein Structure, Tertiary; Superoxide Dismutase; Tyrosine; X-Ray Diffraction | 1992 |
Peroxynitrite inhibits sodium uptake in rat colonic membrane vesicles.
Topics: Amiloride; Animals; Cell Membrane; Colon; Female; Hydrogen-Ion Concentration; Immunoblotting; Kinetics; Nitrates; Oxidants; Rats; Rats, Inbred Strains; Sodium | 1992 |
Peroxynitrite-induced membrane lipid peroxidation: the cytotoxic potential of superoxide and nitric oxide.
Topics: Free Radicals; Hydrogen-Ion Concentration; Hydroxides; Hydroxyl Radical; Iron; Kinetics; Lipid Peroxidation; Liposomes; Malondialdehyde; Membrane Lipids; Nitrates; Nitric Oxide; Oxygen Consumption; Pentetic Acid; Phosphatidylcholines | 1991 |
Reaction of NO with O2-. implications for the action of endothelium-derived relaxing factor (EDRF).
Topics: Hydrogen-Ion Concentration; Kinetics; Nitrates; Nitric Oxide; Superoxides | 1990 |
Trace nitrogenous species in urban atmospheres.
Topics: Air Pollutants; California; Chemical Phenomena; Chemistry; Nitrates; Nitric Acid; Nitrogen Oxides; Nitrous Acid; Urban Health | 1983 |
Involvement of peroxynitrite in N-methyl-D-aspartate- and sodium nitroprusside-induced release of acetylcholine from mouse cerebral cortical neurons.
Topics: Acetylcholine; Animals; Cells, Cultured; Cerebral Cortex; Dizocilpine Maleate; Free Radical Scavengers; Mice; Mice, Inbred Strains; N-Methylaspartate; Neurons; Nitrates; Nitric Oxide Synthase; Nitroprusside; Receptors, N-Methyl-D-Aspartate; Superoxides | 1995 |
Interaction between nitric oxide and superoxide: role in modulating leukocyte adhesion in the postischemic microvasculature.
Topics: Animals; Cell Adhesion; Endothelium, Vascular; Free Radicals; Humans; Intestine, Small; Ischemia; Leukocytes; Leukotriene B4; Microcirculation; Models, Biological; Nitrates; Nitric Oxide; Phospholipases A; Platelet Activating Factor; Reperfusion; Superoxides | 1995 |
Combined effects of nitric oxide and hyperoxia on surfactant function and pulmonary inflammation.
Topics: Animals; Animals, Newborn; Biological Products; Biomarkers; Bronchoalveolar Lavage Fluid; Buffers; Hyperoxia; Methemoglobin; Nitrates; Nitric Oxide; Oxygen; Pneumonia; Pulmonary Surfactants; Respiration; Surface Tension; Swine | 1995 |
TNF-alpha induces peroxynitrite-mediated depletion of lung endothelial glutathione via protein kinase C.
Topics: Animals; Cattle; Cells, Cultured; Cysteine; Endothelium, Vascular; Enzyme Activation; Glutathione; Humans; Luminol; Naphthalenes; Nitrates; Nitric Oxide Synthase; Oxidation-Reduction; Protein Kinase C; Pulmonary Artery; Superoxide Dismutase; Tumor Necrosis Factor-alpha | 1995 |
Peroxynitrite causes apoptosis in rat thymocytes.
Topics: Animals; Apoptosis; Cells, Cultured; DNA; Male; Nitrates; Oxidation-Reduction; Rats; Rats, Sprague-Dawley; Thymus Gland | 1995 |
Reaction between peroxynitrite and hydrogen peroxide: formation of oxygen and slowing of peroxynitrite decomposition.
Topics: Hydrogen Peroxide; Hydrogen-Ion Concentration; Hydroxyl Radical; Nitrates; Oxidation-Reduction; Oxygen; Thermodynamics | 1995 |
Role of oxygen-derived metabolites in the rat gastric mucosal injury induced by nitric oxide donors.
Topics: Animals; Blood Pressure; Catalase; Deferoxamine; Disease Models, Animal; Drug Overdose; Drug Synergism; Endothelins; Free Radical Scavengers; Gastric Mucosa; Infusions, Intra-Arterial; Infusions, Intravenous; Male; Nitrates; Nitric Oxide; Nitroprusside; Penicillamine; Rats; Rats, Wistar; Reactive Oxygen Species; S-Nitroso-N-Acetylpenicillamine; Stomach Ulcer; Superoxide Dismutase; Thiourea; Vasodilator Agents | 1995 |
Formation of 8-nitroguanine in DNA treated with peroxynitrite in vitro and its rapid removal from DNA by depurination.
Topics: Animals; Antioxidants; Apurinic Acid; Cattle; Deferoxamine; DNA; Free Radicals; Guanine; Nitrates | 1995 |
Nitric oxide, superoxide and peroxynitrite: putative mediators of NMDA-induced cell death in cerebellar granule cells.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Catalase; Cell Death; Cells, Cultured; Cerebellum; Cyclic GMP; Cyclic N-Oxides; Electron Spin Resonance Spectroscopy; Mice; Molsidomine; N-Methylaspartate; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Receptors, N-Methyl-D-Aspartate; Superoxide Dismutase; Superoxides; Xanthine Oxidase | 1993 |
Paradoxical fate and biological action of peroxynitrite on human platelets.
Topics: Antigens, CD; Blood Platelets; Cell Adhesion Molecules; Collagen; Epoprostenol; Glutathione; Hemoglobins; Humans; In Vitro Techniques; Indomethacin; Kinetics; Nitrates; Nitroso Compounds; P-Selectin; Penicillamine; Platelet Aggregation; Platelet Membrane Glycoproteins; S-Nitroso-N-Acetylpenicillamine; S-Nitrosoglutathione; Serum Albumin; Time Factors; Vasodilator Agents | 1994 |
Production of nitric oxide and peroxynitrite in the lung during acute endotoxemia.
Topics: Amino Acid Oxidoreductases; Animals; Enzyme Induction; Escherichia coli; Female; Lipopolysaccharides; Lung; Macrophage Activation; Macrophages, Alveolar; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley; Toxemia | 1994 |
Endotoxin triggers the expression of an inducible isoform of nitric oxide synthase and the formation of peroxynitrite in the rat aorta in vivo.
Topics: Amino Acid Oxidoreductases; Animals; Aorta; Calcium; Endotoxins; Fluorescent Antibody Technique; Lipopolysaccharides; Male; Nitrates; Nitric Oxide Synthase; Rats; Rats, Wistar; Tyrosine | 1995 |
Modulation of particulate nitric oxide synthase activity and peroxynitrite synthesis in cholesterol enriched endothelial cell membranes.
Topics: Amino Acid Oxidoreductases; Animals; Cattle; Cell Membrane; Cholesterol; Citrulline; Cyclic GMP; Endothelium, Vascular; Enzyme Activation; Manganese; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Superoxides | 1995 |
Hyperbaric oxygenation reduces the cytostatic activity and transcription of nitric oxide synthetase gene of mouse peritoneal macrophages.
Topics: Amino Acid Oxidoreductases; Animals; Cell Survival; Hyperbaric Oxygenation; Leukemia L1210; Macrophages, Peritoneal; Mice; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Oxidative Stress; RNA, Messenger; Superoxides; Transcription, Genetic; Tumor Cells, Cultured | 1995 |
Reactive species in ischemic rat lung injury: contribution of peroxynitrite.
Topics: Animals; Arginine; Immunohistochemistry; Ischemia; Lung; Male; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Nitrites; Perfusion; Pressure; Pulmonary Circulation; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Staining and Labeling; Tyrosine | 1995 |
Formation of 8-nitroguanine by the reaction of guanine with peroxynitrite in vitro.
Topics: Carcinogens; DNA; DNA Damage; Guanine; Hydrogen-Ion Concentration; Kinetics; Nitrates; Nucleosides | 1995 |
Peroxynitrite-mediated oxidation of dihydrorhodamine 123 occurs in early stages of endotoxic and hemorrhagic shock and ischemia-reperfusion injury.
Topics: Animals; Male; Nitrates; Oxidation-Reduction; Rats; Rats, Wistar; Reperfusion Injury; Rhodamines; Shock, Hemorrhagic; Shock, Septic | 1995 |
Peroxynitrite-induced cytotoxicity in PC12 cells: evidence for an apoptotic mechanism differentially modulated by neurotrophic factors.
Topics: Animals; Apoptosis; Cell Survival; Coloring Agents; DNA Damage; Fibroblast Growth Factor 2; Nerve Growth Factors; Neurons; Nitrates; PC12 Cells; Rats | 1995 |
Stopped-flow kinetic study of the reaction of ascorbic acid with peroxynitrite.
Topics: Ascorbic Acid; Electron Transport; Free Radicals; Hydrogen-Ion Concentration; In Vitro Techniques; Kinetics; Methionine; Models, Chemical; Nitrates; Oxidation-Reduction | 1995 |
Peroxynitrite causes DNA damage and oxidation of thiols in rat thymocytes [corrected].
Topics: Animals; Antioxidants; Cell Survival; Chromans; Diffusion; DNA Damage; Dose-Response Relationship, Drug; Free Radical Scavengers; Half-Life; Male; Nitrates; Nucleic Acid Conformation; Oxidants; Oxidation-Reduction; Rats; Rats, Sprague-Dawley; Spectrometry, Fluorescence; Sulfhydryl Compounds; Thymus Gland | 1995 |
Peroxynitrite-mediated inhibition of DOPA synthesis in PC12 cells.
Topics: Animals; Dihydroxyphenylalanine; Molsidomine; Nitrates; Oxidation-Reduction; PC12 Cells; Rats; Tyrosine | 1995 |
Genetic and redox determinants of nitric oxide cytotoxicity in a Salmonella typhimurium model.
Topics: Base Sequence; DNA Primers; Genes, Bacterial; Glutathione; Microbial Sensitivity Tests; Molecular Sequence Data; Molsidomine; Mutagenesis; Nitrates; Nitric Oxide; Nitroso Compounds; Oxidation-Reduction; Polyamines; S-Nitrosoglutathione; Salmonella typhimurium; Species Specificity; Vasodilator Agents | 1995 |
Formation of F2-isoprostanes during oxidation of human low-density lipoprotein and plasma by peroxynitrite.
Topics: Antihypertensive Agents; Arachidonic Acid; Arteriosclerosis; Catalysis; Humans; In Vitro Techniques; Lipid Peroxidation; Lipoproteins, LDL; Molsidomine; Nitrates; Nitric Oxide; Oxidation-Reduction; Platelet Aggregation Inhibitors; Prostaglandins F, Synthetic; Superoxide Dismutase; Superoxides; Vasodilator Agents | 1995 |
On-line measurement of nitric oxide generation in buffer-perfused rabbit lungs.
Topics: Animals; Arginine; Calcimycin; Female; In Vitro Techniques; Luminescent Measurements; Lung; Male; Nitrates; Nitric Oxide; Nitrites; omega-N-Methylarginine; Oxygen; Perfusion; Rabbits; Vanadium Compounds | 1995 |
Peroxynitrite-induced accumulation of cyclic GMP in endothelial cells and stimulation of purified soluble guanylyl cyclase. Dependence on glutathione and possible role of S-nitrosation.
Topics: Animals; Cells, Cultured; Cyclic GMP; Endothelium, Vascular; Glutathione; Guanylate Cyclase; Nitrates; Nitric Oxide; Nitroso Compounds; S-Nitrosoglutathione; Swine | 1995 |
Antibody transformation by peroxynitrite as determined using capillary electrophoresis: a feasibility study.
Topics: Antibodies; Cyclic AMP; Drug Interactions; Electrophoresis; Feasibility Studies; Nitrates; Penicillamine; Plasminogen Activator Inhibitor 1; Time Factors | 1995 |
Peroxynitrite-induced apoptosis in HL-60 cells.
Topics: Apoptosis; Humans; Leukemia, Promyelocytic, Acute; Nitrates; Tumor Cells, Cultured | 1995 |
Desferrioxamine inhibition of the hydroxyl radical-like reactivity of peroxynitrite: role of the hydroxamic groups.
Topics: Cyclic N-Oxides; Deferoxamine; Dimethyl Sulfoxide; Electron Spin Resonance Spectroscopy; Hydrogen Peroxide; Hydroxamic Acids; Hydroxyl Radical; Luminescent Measurements; Luminol; Nitrates; Oxidation-Reduction; Spectrophotometry | 1995 |
Apoptosis and necrosis: two distinct events induced, respectively, by mild and intense insults with N-methyl-D-aspartate or nitric oxide/superoxide in cortical cell cultures.
Topics: Animals; Apoptosis; Cells, Cultured; Cerebral Cortex; Cysteine; DNA; Free Radicals; Kinetics; Molsidomine; N-Methylaspartate; Necrosis; Neurons; Nitrates; Nitric Oxide; Oxidative Stress; Rats; S-Nitrosothiols; Superoxide Dismutase; Superoxides | 1995 |
Spin trap studies on the decomposition of peroxynitrite.
Topics: Animals; Cattle; Cyclic N-Oxides; Electron Spin Resonance Spectroscopy; Erythrocytes; Hydroxyl Radical; Kinetics; Mathematics; Models, Theoretical; Nitrates; Oxidation-Reduction; Spin Labels; Sulfhydryl Compounds; Superoxide Dismutase; Superoxides | 1995 |
Nitric oxide-induced [3H] GABA release from cerebral cortical neurons is mediated by peroxynitrite.
Topics: Animals; Cells, Cultured; Cerebral Cortex; Ceruloplasmin; gamma-Aminobutyric Acid; Mice; Neurons; Nitrates; Nitric Oxide; Nitroprusside; Penicillamine; S-Nitroso-N-Acetylpenicillamine; Superoxide Dismutase; Tritium | 1995 |
Interaction of surfactant mixtures with reactive oxygen and nitrogen species.
Topics: Animals; Antioxidants; Biological Products; Drug Combinations; Fatty Alcohols; Formaldehyde; Free Radical Scavengers; Free Radicals; Hydrogen Peroxide; In Vitro Techniques; Lung; Nitrates; Nitrogen; Phosphorylcholine; Polyethylene Glycols; Pulmonary Surfactants; Rabbits; Reactive Oxygen Species; Surface Tension; Xanthine Oxidase | 1995 |
Oxidative DNA damage induced by simultaneous generation of nitric oxide and superoxide.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Cattle; Deoxyguanosine; Deoxyribonucleotides; DNA; DNA Damage; Free Radical Scavengers; Humans; Molsidomine; Nitrates; Nitric Oxide; Oxidative Stress; Superoxides | 1995 |
Modification of aromatic amino acids by reactive nitrogen species.
Topics: Free Radicals; Hydrogen-Ion Concentration; Hydroxyl Radical; Hydroxylation; Kinetics; Mannitol; Nitrates; Nitric Oxide; Nitrogen Dioxide; Nitrogen Oxides; Oxidants; Phenylalanine; Tyrosine | 1995 |
Evidence for in vivo peroxynitrite production in human acute lung injury.
Topics: Cadaver; Child; Humans; Immunohistochemistry; Inflammation; Lung; Lung Diseases; Nitrates | 1995 |
Effect of peroxynitrite on the mitochondrial respiratory chain: differential susceptibility of neurones and astrocytes in primary culture.
Topics: Animals; Astrocytes; Brain; Cells, Cultured; Citrate (si)-Synthase; Electron Transport; Electron Transport Complex I; Electron Transport Complex IV; Glutathione; L-Lactate Dehydrogenase; Mitochondria; NADH, NADPH Oxidoreductases; Neurons; Nitrates; Rats; Rats, Wistar; Succinate Cytochrome c Oxidoreductase | 1995 |
Formation of F2-isoprostanes during the oxidation of human low density lipoprotein by peroxynitrite.
Topics: Arachidonic Acids; Dinoprost; Humans; Kinetics; Lipoproteins, LDL; Molsidomine; Nitrates; Oxidation-Reduction; Platelet Aggregation Inhibitors | 1995 |
Endogenous peroxynitrite is involved in the inhibition of mitochondrial respiration in immuno-stimulated J774.2 macrophages.
Topics: Animals; Cell Line; In Vitro Techniques; Macrophages; Mice; Nitrates; Nitric Oxide; Oxygen Consumption; Pyrogallol; Superoxides | 1995 |
Participation of peroxynitrite in acetylcholine release induced by nitric oxide generators.
Topics: Acetylcholine; Animals; Cells, Cultured; Ceruloplasmin; Hemoglobins; Mice; Mice, Inbred Strains; Neurons; Nitrates; Nitric Oxide; Nitroprusside; Penicillamine; S-Nitroso-N-Acetylpenicillamine; Superoxide Dismutase; Superoxides; Vasodilator Agents | 1995 |
Peroxynitrite-mediated oxidative protein modifications.
Topics: Animals; Cysteine; Electrophoresis, Polyacrylamide Gel; Fluorescence; Hydrogen-Ion Concentration; Male; Nitrates; Oxidation-Reduction; Oxidative Stress; Phenylhydrazines; Rats; Rats, Sprague-Dawley; Serum Albumin, Bovine; Tryptophan; Tyrosine | 1995 |
Peroxynitrite stimulates vascular smooth muscle cell cyclic GMP synthesis.
Topics: Animals; Aorta; Cattle; Cells, Cultured; Cyclic GMP; Endothelium, Vascular; Enzyme Activation; Glutathione; Guanylate Cyclase; Kinetics; Muscle, Smooth, Vascular; Nitrates; Nitric Oxide; Oxyhemoglobins; Rats | 1995 |
Nitric oxide: a central regulatory species in pulmonary oxidant reactions.
Topics: Animals; Humans; Lung; Nitrates; Nitric Oxide; Oxidation-Reduction | 1995 |
Peroxynitrite causes DNA nicks in plasmid pBR322.
Topics: Benzoates; Benzoic Acid; Dimethyl Sulfoxide; DNA Damage; DNA, Superhelical; Electrophoresis, Agar Gel; Free Radical Scavengers; Mannitol; Nitrates; Plasmids | 1995 |
Does peroxynitrite generate hydroxyl radical?
Topics: Electron Spin Resonance Spectroscopy; Hydroxyl Radical; Nitrates | 1995 |
Generation of thiyl and ascorbyl radicals in the reaction of peroxynitrite with thiols and ascorbate at physiological pH.
Topics: Ascorbic Acid; Cyclic N-Oxides; Dehydroascorbic Acid; Electron Spin Resonance Spectroscopy; Free Radicals; Hydrogen-Ion Concentration; Models, Biological; Nitrates; Spin Labels; Sulfhydryl Compounds | 1994 |
Apparent hydroxyl radical generation without transition metal catalysis and tyrosine nitration during oxidation of the anti-tubercular drug, isonicotinic acid hydrazide.
Topics: Catalase; Hydroxyl Radical; Isoniazid; Kinetics; Metals; Nitrates; Oxidation-Reduction; Spectrophotometry, Ultraviolet; Thiobarbituric Acid Reactive Substances; Tyrosine | 1994 |
Peroxynitrite induces both vasodilatation and impaired vascular relaxation in the isolated perfused rat heart.
Topics: Acetylcholine; Animals; Coronary Circulation; Epoprostenol; Isoproterenol; Male; Nitrates; Nitric Oxide; Penicillamine; Rats; Rats, Wistar; S-Nitroso-N-Acetylpenicillamine; Vasodilation | 1994 |
The comparative toxicity of nitric oxide and peroxynitrite to Escherichia coli.
Topics: Escherichia coli; Free Radicals; Hydrogen Peroxide; Molsidomine; Nitrates; Nitric Oxide; Oxyhemoglobins; Toxicity Tests | 1995 |
Peroxynitrite-dependent chemiluminescence of amino acids, proteins, and intact cells.
Topics: Amino Acids; Animals; Bicarbonates; Cells, Cultured; Fatty Acids; Hemin; Histones; Hydrogen-Ion Concentration; Luminescent Measurements; Nitrates; Nucleic Acids; Nucleotides; Oxidation-Reduction; Peroxides; Proteins; Serum Albumin, Bovine; Spectrophotometry; tert-Butylhydroperoxide; Trypanosomatina; Tryptophan; Tyrosine | 1995 |
Sensitivity of the essential zinc-thiolate moiety of yeast alcohol dehydrogenase to hypochlorite and peroxynitrite.
Topics: Alcohol Dehydrogenase; Cysteine; Histidine; Hydrogen Peroxide; Hypochlorous Acid; Kinetics; Molsidomine; Nitrates; Sulfhydryl Compounds; Taurine; Zinc | 1995 |
A practical method for preparing peroxynitrite solutions of low ionic strength and free of hydrogen peroxide.
Topics: Azides; Buffers; Drug Contamination; Drug Stability; Free Radicals; Freezing; Hydrogen Peroxide; Hydrogen-Ion Concentration; Nitrates; Osmolar Concentration; Ozone; Sodium Azide; Solutions; Spectrophotometry; Tyrosine | 1995 |
The kinetics of the oxidation of L-ascorbic acid by peroxynitrite.
Topics: Ascorbic Acid; Electron Spin Resonance Spectroscopy; Hydrogen-Ion Concentration; Kinetics; Mathematics; Nitrates; Oxidation-Reduction; Spectrophotometry; Temperature; Thermodynamics | 1995 |
Nitric oxide regulation of superoxide and peroxynitrite-dependent lipid peroxidation. Formation of novel nitrogen-containing oxidized lipid derivatives.
Topics: Hydroxyl Radical; Lipid Peroxidation; Liposomes; Nitrates; Nitric Oxide; Oxidation-Reduction; Superoxides | 1994 |
Concurrent generation of nitric oxide and superoxide damages surfactant protein A.
Topics: Humans; Molsidomine; Nitrates; Nitric Oxide; Oxidation-Reduction; Penicillamine; Proteolipids; Pulmonary Surfactant-Associated Protein A; Pulmonary Surfactant-Associated Proteins; Pulmonary Surfactants; Reactive Oxygen Species; Rhodamines; S-Nitroso-N-Acetylpenicillamine; Superoxides; Time Factors | 1994 |
The oxidation of alpha-tocopherol and trolox by peroxynitrite.
Topics: Acetonitriles; Chromans; Chromatography, High Pressure Liquid; Electron Spin Resonance Spectroscopy; Free Radicals; Hydrolysis; Methanol; Nitrates; Oxidation-Reduction; Solvents; Vitamin E | 1994 |
Interactions of peroxynitrite with human plasma and its constituents: oxidative damage and antioxidant depletion.
Topics: Antioxidants; Ascorbic Acid; Blood Proteins; Glutathione; Humans; Kinetics; Lipid Peroxides; Nitrates; Oxidants; Oxidation-Reduction; Serum Albumin; Vitamin E | 1994 |
ESR spin trapping investigation on peroxynitrite decomposition: no evidence for hydroxyl radical production.
Topics: Ascorbic Acid; Cyclic N-Oxides; Cysteine; Electron Spin Resonance Spectroscopy; Formates; Free Radicals; Glutathione; Hydroxyl Radical; Nitrates; Penicillamine; Spin Labels | 1994 |
Superoxide and peroxynitrite inactivate aconitases, but nitric oxide does not.
Topics: Aconitate Hydratase; Animals; Escherichia coli; Humans; Nitrates; Nitric Oxide; Superoxides; Swine | 1994 |
Aconitase is readily inactivated by peroxynitrite, but not by its precursor, nitric oxide.
Topics: Aconitate Hydratase; Animals; Iron-Sulfur Proteins; Kinetics; Mitochondria, Heart; Nitrates; Nitric Oxide; Nitroso Compounds; Sulfhydryl Compounds; Swine | 1994 |
One- and two-electron oxidations of methionine by peroxynitrite.
Topics: Chelating Agents; Ethylenes; Ferric Compounds; Free Radicals; Isomerism; Kinetics; Methionine; Nitrates; Oxidation-Reduction | 1994 |
Singlet molecular oxygen production in the reaction of peroxynitrite with hydrogen peroxide.
Topics: Free Radicals; Hydrogen Peroxide; Infrared Rays; Luminescent Measurements; Nitrates; Oxygen; Photons | 1994 |
Quantitation of nitrotyrosine levels in lung sections of patients and animals with acute lung injury.
Topics: Adolescent; Animals; Child; Child, Preschool; Female; Fluorescent Antibody Technique; Humans; Infant; Infant, Newborn; Lung; Male; Microtomy; Nitrates; Rats; Rats, Sprague-Dawley; Respiratory Distress Syndrome, Newborn; Tyrosine | 1994 |
Peroxynitrite-mediated oxidation of dihydrorhodamine 123.
Topics: Animals; Cattle; Cysteine; Hydrogen-Ion Concentration; Kinetics; Liver; Nitrates; Oxidation-Reduction; Rhodamines; Superoxide Dismutase; Uric Acid | 1994 |
Structure activity relationships of peroxynitrite scavengers an approach to nitric oxide neurotoxicity.
Topics: Animals; Antigen-Antibody Reactions; Brain; Cyclic AMP; Cysteine; Dose-Response Relationship, Drug; Free Radical Scavengers; Immunoglobulin G; Nitrates; Nitric Oxide; Radioimmunoassay; Structure-Activity Relationship | 1994 |
Oxidative chemistry of peroxynitrite.
Topics: Artifacts; Drug Contamination; Hydrogen Peroxide; Hydrogen-Ion Concentration; Indicators and Reagents; Kinetics; Nitrates; Oxidation-Reduction; Oxygen; Sodium Nitrite | 1994 |
Peroxynitrite inhibition of oxygen consumption and sodium transport in alveolar type II cells.
Topics: Amiloride; Animals; Biological Transport; Edetic Acid; Ferric Compounds; Nitrates; Ouabain; Oxygen Consumption; Pulmonary Alveoli; Rabbits; Reactive Oxygen Species; Rubidium; Sodium; Xanthine; Xanthine Oxidase; Xanthines | 1994 |
Mechanism of covalent modification of glyceraldehyde-3-phosphate dehydrogenase at its active site thiol by nitric oxide, peroxynitrite and related nitrosating agents.
Topics: Adenosine Diphosphate Ribose; Binding Sites; Borates; Dithiothreitol; Glyceraldehyde-3-Phosphate Dehydrogenases; Molsidomine; Nitrates; Nitric Oxide; Oxidation-Reduction; Sulfhydryl Compounds; Superoxide Dismutase | 1994 |
Peroxynitrite-mediated oxidation of albumin to the protein-thiyl free radical.
Topics: Cyclic N-Oxides; Electron Spin Resonance Spectroscopy; Free Radicals; Hydrogen-Ion Concentration; Nitrates; Nitrogen Oxides; Oxidation-Reduction; Serum Albumin, Bovine; Spin Labels | 1994 |
Reaction of peroxynitrite with oxyhaemoglobin: interference with photometrical determination of nitric oxide.
Topics: Electrochemistry; Kinetics; Molsidomine; Nitrates; Nitric Oxide; Oxyhemoglobins; Photochemistry; Spectrophotometry; Superoxide Dismutase | 1994 |
On the pH-dependent yield of hydroxyl radical products from peroxynitrite.
Topics: Benzothiazoles; Dimethyl Sulfoxide; Formaldehyde; Free Radical Scavengers; Free Radicals; Hydrogen-Ion Concentration; Hydroxyl Radical; In Vitro Techniques; Isomerism; Nitrates; Oxidation-Reduction; Sulfonic Acids | 1994 |
The inhibition of silica-induced lung inflammation by dexamethasone as measured by bronchoalveolar lavage fluid parameters and peroxynitrite-dependent chemiluminescence.
Topics: Administration, Inhalation; Animals; Arginine; Bronchoalveolar Lavage Fluid; Dexamethasone; Disease Models, Animal; Inflammation; Luminescent Measurements; Lung; Lung Diseases; Male; NG-Nitroarginine Methyl Ester; Nitrates; Rats; Rats, Inbred F344; Silicon Dioxide; Superoxide Dismutase | 1994 |
Peroxynitrite inhibition of oxygen consumption and ion transport in alveolar type II pneumocytes.
Topics: Humans; In Vitro Techniques; Ion Transport; Nitrates; Oxygen Consumption; Pulmonary Alveoli; Sodium | 1994 |
Structural and functional alterations of surfactant protein A by peroxynitrite.
Topics: Animals; Cattle; Glycoproteins; Nitrates; Proteolipids; Pulmonary Surfactant-Associated Proteins; Pulmonary Surfactants; Reactive Oxygen Species | 1994 |
Kinetics of nitric oxide and hydrogen peroxide production and formation of peroxynitrite during the respiratory burst of human neutrophils.
Topics: Humans; Hydrogen Peroxide; In Vitro Techniques; Kinetics; Luminol; Neutrophils; Nitrates; Nitric Oxide; Oxygen Consumption; Respiratory Burst; Tetradecanoylphorbol Acetate | 1994 |
Peroxynitrite, a product of superoxide and nitric oxide, produces coronary vasorelaxation in dogs.
Topics: Animals; Arteries; Coronary Vessels; Dogs; Fluorescence; In Vitro Techniques; Light; Male; Nitrates; Nitric Oxide; Sodium Nitrite; Superoxides; Vasodilator Agents | 1994 |
Peroxynitrite releases copper from caeruloplasmin: implications for atherosclerosis.
Topics: Arteriosclerosis; Ceruloplasmin; Copper; Humans; Nitrates; Oxidation-Reduction | 1994 |
Spin-trapping studies of peroxynitrite decomposition and of 3-morpholinosydnonimine N-ethylcarbamide autooxidation: direct evidence for metal-independent formation of free radical intermediates.
Topics: Benzoates; Cyclic N-Oxides; Deoxyribose; Electron Spin Resonance Spectroscopy; Free Radicals; Glutathione; Hydroxyl Radical; Models, Chemical; Molsidomine; Nitrates; Oxidation-Reduction | 1994 |
Agonist-induced peroxynitrite production from endothelial cells.
Topics: Acridines; Animals; Aorta; Arginine; Bradykinin; Calcimycin; Catalase; Cattle; Cells, Cultured; Cysteine; Dimethyl Sulfoxide; Endothelium, Vascular; Kinetics; Luminescent Measurements; Luminol; Mannitol; Methionine; Models, Biological; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Stereoisomerism; Superoxide Dismutase; Uric Acid | 1994 |
Peroxynitrite causes calcium efflux from mitochondria which is prevented by Cyclosporin A.
Topics: Animals; Calcium; Cyclosporine; Female; Kinetics; Mitochondria, Liver; Mitochondrial Swelling; Nitrates; Rats; Rats, Wistar | 1994 |
Involvement of nitric oxide and nitrosothiols in relaxation of pulmonary arteries to peroxynitrite.
Topics: Aminoquinolines; Animals; Cattle; Free Radical Scavengers; Glutathione; In Vitro Techniques; Kinetics; Methylene Blue; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Nitrates; Nitric Oxide; Nitroso Compounds; Potassium; Pulmonary Artery; Time Factors | 1994 |
Peroxynitrite-induced rat colitis--a new model of colonic inflammation.
Topics: Animals; Colitis; Disease Models, Animal; Inflammatory Bowel Diseases; Intestinal Mucosa; Leukotrienes; Male; Nitrates; Nitric Oxide; Rats | 1993 |
Mechanisms of peroxynitrite-induced injury to pulmonary surfactants.
Topics: Animals; Blotting, Western; Bronchoalveolar Lavage Fluid; Cattle; Dogs; Electrophoresis, Polyacrylamide Gel; Glycoproteins; Humans; Kinetics; Lipid Peroxidation; Molecular Weight; Nitrates; Proteolipids; Pulmonary Surfactant-Associated Protein A; Pulmonary Surfactant-Associated Proteins; Pulmonary Surfactants; Surface Properties; Time Factors | 1993 |
Superoxide and peroxynitrite in atherosclerosis.
Topics: Acetylcholine; Animals; Arteriosclerosis; Diet, Atherogenic; Femoral Artery; Hydrogen-Ion Concentration; Hypercholesterolemia; In Vitro Techniques; Lipid Peroxidation; Lipoproteins, VLDL; Liposomes; Nitrates; Nitric Oxide; Rabbits; Superoxide Dismutase; Superoxides; Vasodilation | 1994 |
Inhibition of mitochondrial electron transport by peroxynitrite.
Topics: Animals; Electron Transport; Hydrogen Peroxide; Kinetics; Male; Mitochondria, Heart; Nitrates; Oxygen Consumption; Rats; Succinate Dehydrogenase | 1994 |
Peroxynitrite inactivates thiol-containing enzymes of Trypanosoma cruzi energetic metabolism and inhibits cell respiration.
Topics: Adenosine Triphosphatases; alpha 1-Antitrypsin; Animals; Chelating Agents; Energy Metabolism; Ethylmaleimide; Humans; Kinetics; Lung; Mitochondria, Heart; NADH Dehydrogenase; Nitrates; Succinate Dehydrogenase; Trypanosoma cruzi | 1994 |
Aromatic hydroxylation and nitration of phenylalanine and tyrosine by peroxynitrite. Evidence for hydroxyl radical production from peroxynitrite.
Topics: Hydroxyl Radical; Hydroxylation; Nitrates; Phenylalanine; Serum Albumin, Bovine; Thermodynamics; Tyrosine; Uric Acid | 1994 |
Peroxynitrite-mediated cytotoxicity to Trypanosoma cruzi.
Topics: Animals; Chelating Agents; DNA, Protozoan; Free Radicals; Nitrates; Trypanosoma cruzi | 1993 |
ALS, SOD and peroxynitrite.
Topics: Amyotrophic Lateral Sclerosis; Humans; Nitrates; Superoxide Dismutase | 1993 |
Peroxynitrite and atherosclerosis.
Topics: Arteriosclerosis; Humans; Lipoproteins, LDL; Nitrates; Oxidation-Reduction; Vitamin E | 1993 |
Peroxynitrite modification of low-density lipoprotein leads to recognition by the macrophage scavenger receptor.
Topics: Cell Line; Humans; Lipoproteins, LDL; Macrophages; Membrane Proteins; Nitrates; Oxidation-Reduction; Receptors, Immunologic; Receptors, Lipoprotein; Receptors, Scavenger; Scavenger Receptors, Class B; Vitamin E | 1993 |
Peroxynitrite-induced luminol chemiluminescence.
Topics: Antioxidants; Bicarbonates; Free Radicals; Hydrogen-Ion Concentration; Kinetics; Luminescent Measurements; Luminol; Nitrates; Oxidation-Reduction; Spectrophotometry; Superoxide Dismutase; Superoxides | 1993 |
'Footprinting' proteins on DNA with peroxonitrous acid.
Topics: Anions; Bacteriophage lambda; Deoxyribonuclease I; DNA-Binding Proteins; DNA, Viral; Edetic Acid; Ferric Compounds; Formaldehyde; Free Radicals; Hydrogen Peroxide; Hydrogen-Ion Concentration; Hydroxides; Hydroxyl Radical; Mutagenesis, Site-Directed; Nitrates; Nitrites; Oxidation-Reduction; Plasmids | 1993 |
A redox-based mechanism for the neuroprotective and neurodestructive effects of nitric oxide and related nitroso-compounds.
Topics: Animals; Brain; Cell Death; Cells, Cultured; Cysteine; Free Radicals; Molsidomine; Neurons; Nitrates; Nitric Oxide; Nitroglycerin; Nitroprusside; Oxidation-Reduction; Rats; Receptors, N-Methyl-D-Aspartate; S-Nitrosothiols; Superoxides | 1993 |
Interaction of myeloperoxidase with peroxynitrite. A comparison with lactoperoxidase, horseradish peroxidase and catalase.
Topics: Catalase; Cells, Cultured; Horseradish Peroxidase; Humans; Hydrogen-Ion Concentration; Kinetics; Lactoperoxidase; Leukocytes; Nitrates; Peroxidase; Spectrum Analysis | 1993 |
The reaction of no with superoxide.
Topics: Hydrogen-Ion Concentration; Kinetics; Lasers; Nitrates; Nitric Oxide; Photolysis; Solutions; Spectrophotometry; Superoxides | 1993 |
Involvement of superoxide and xanthine oxidase in neutrophil-independent rat gastric damage induced by NO donors.
Topics: Allopurinol; Animals; Dose-Response Relationship, Drug; Gastric Mucosa; Male; Nitrates; Nitric Oxide; Nitroprusside; Rats; Rats, Wistar; Superoxide Dismutase; Superoxides; Xanthine; Xanthines | 1995 |
Peroxynitrite formed by simultaneous nitric oxide and superoxide generation causes cyclosporin-A-sensitive mitochondrial calcium efflux and depolarisation.
Topics: Animals; Biological Transport; Calcium; Cyclosporine; Female; Intracellular Membranes; Membrane Potentials; Mitochondria, Liver; Nitrates; Nitric Oxide; Rats; Rats, Wistar; Superoxides | 1995 |
Nitration of tyrosyl-residues from extra- and intracellular proteins in human whole blood.
Topics: Blood Proteins; Calcimycin; Humans; Ionophores; Kinetics; Neutrophils; Nitrates; Tetradecanoylphorbol Acetate; Time Factors; Tyrosine | 1995 |
Role of inducible nitric oxide synthase (iNOS) and peroxynitrite in gut inflammation.
Topics: Animals; Enzyme Induction; Female; Gastroenteritis; Gene Expression Regulation, Enzymologic; Guinea Pigs; Inflammation Mediators; Male; Nitrates; Nitric Oxide; Nitric Oxide Synthase | 1995 |
Mutant enzyme provides new insights into the cause of ALS.
Topics: Amyotrophic Lateral Sclerosis; Animals; Apoptosis; Cells, Cultured; Free Radicals; Humans; Lipid Peroxidation; Mice; Mutation; Neurons; Nitrates; Peroxidases; Selenium; Superoxide Dismutase; Vitamin E | 1996 |
Spin trapping of O-, C-, and S-centered radicals and peroxynitrite by 2H-imidazole-1-oxides.
Topics: Electron Spin Resonance Spectroscopy; Free Radicals; Hydroxyl Radical; Imidazoles; Lipids; Nitrates; Nitroimidazoles; Peroxides; Solubility; Spin Labels; Spin Trapping; Sulfhydryl Compounds; Superoxides; Water | 1996 |
Protection against peroxynitrite-dependent tyrosine nitration and alpha 1-antiproteinase inactivation by oxidized and reduced lipoic acid.
Topics: alpha 1-Antitrypsin; Antioxidants; Free Radical Scavengers; Humans; In Vitro Techniques; Nitrates; Nitric Oxide; Oxidation-Reduction; Reactive Oxygen Species; Thioctic Acid; Tyrosine | 1996 |
Modulation of iron regulatory protein functions. Further insights into the role of nitrogen- and oxygen-derived reactive species.
Topics: Aconitate Hydratase; Animals; Cell Line; Enzyme Inhibitors; Ferritins; Hemoglobins; Hydrogen Peroxide; Iron-Regulatory Proteins; Mice; Molsidomine; Nitrates; Reactive Oxygen Species; RNA-Binding Proteins; RNA, Messenger; Superoxide Dismutase; Superoxides | 1996 |
Peroxynitrite-induced mutation spectra of pSP189 following replication in bacteria and in human cells.
Topics: Base Sequence; Cell Line; DNA Replication; DNA, Recombinant; Escherichia coli; Genes, Suppressor; Genetic Vectors; Humans; Molecular Sequence Data; Mutagenicity Tests; Mutagens; Nitrates; Oxidants; RNA, Transfer | 1996 |
Exposure to the parkinsonian neurotoxin 1-methyl-4-phenylpyridinium (MPP+) and nitric oxide simultaneously causes cyclosporin A-sensitive mitochondrial calcium efflux and depolarisation.
Topics: 1-Methyl-4-phenylpyridinium; Animals; Calcium; Cattle; Cyclosporine; Dopamine Agents; Drug Synergism; Female; Intracellular Membranes; Membrane Potentials; Mitochondria, Heart; Mitochondria, Liver; Nitrates; Nitric Oxide; Rats; Rats, Wistar; Superoxides | 1996 |
Nitration of tyrosine by hydrogen peroxide and nitrite.
Topics: Hydrogen Peroxide; Hydrogen-Ion Concentration; Hydroxylation; Inflammation; Iron; Nitrates; Oxidative Stress; Salicylates; Salicylic Acid; Sodium Nitrite; Tyrosine | 1995 |
Nitric oxide synthase inhibitors decrease human polymorphonuclear leukocyte luminol-dependent chemiluminescence.
Topics: Animals; Arginine; Enzyme Inhibitors; Humans; Luminescent Measurements; Luminol; Macrophages; NADH, NADPH Oxidoreductases; NADPH Oxidases; Neutrophils; Nitrates; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Ornithine; Oxidation-Reduction; Oxyhemoglobins; Rats; Superoxide Dismutase; Superoxides | 1995 |
Peroxynitrite-mediated DNA strand breakage activates poly-adenosine diphosphate ribosyl synthetase and causes cellular energy depletion in macrophages stimulated with bacterial lipopolysaccharide.
Topics: Adenosine Diphosphate Ribose; Animals; Cell Line; DNA Damage; Energy Metabolism; Enzyme Activation; Hydrogen Peroxide; Lipopolysaccharides; Macrophage Activation; Macrophages, Peritoneal; Male; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Oxidation-Reduction; Rats; Rats, Wistar; Rhodamines; RNA Ligase (ATP); Superoxides | 1996 |
Accumulation of nitrotyrosine on the SERCA2a isoform of SR Ca-ATPase of rat skeletal muscle during aging: a peroxynitrite-mediated process?
Topics: Aging; Animals; Calcium; Calcium-Transporting ATPases; Male; Muscle, Skeletal; Nitrates; Rats; Rats, Inbred F344; Sarcoplasmic Reticulum; Tyrosine | 1996 |
Peroxynitrite stimulates the pyridine nucleotide-linked Ca2+ release from intact rat liver mitochondria.
Topics: Animals; Calcium; Cyclosporine; Free Radicals; Hydrolysis; In Vitro Techniques; Mitochondria, Liver; NAD; Nitrates; Oxidation-Reduction; Rats | 1996 |
Peroxynitrite formed by simultaneous generation of nitric oxide and superoxide selectively inhibits bovine aortic prostacyclin synthase.
Topics: Animals; Aorta; Cattle; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Epoprostenol; Hypochlorous Acid; Intramolecular Oxidoreductases; Isomerases; Microsomes; Nitrates; Nitric Oxide; Oxidants; Reperfusion Injury; Superoxides | 1996 |
Downregulation of Cu/Zn superoxide dismutase leads to cell death via the nitric oxide-peroxynitrite pathway.
Topics: Acetylcysteine; Animals; Cell Death; Chelating Agents; Cyclic AMP; Down-Regulation; Free Radicals; Neuroprotective Agents; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Oligonucleotides, Antisense; PC12 Cells; Peptides; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Rats; Superoxide Dismutase | 1996 |
Peroxynitrite-mediated formation of free radicals in human plasma: EPR detection of ascorbyl, albumin-thiyl and uric acid-derived free radicals.
Topics: Ascorbic Acid; Cyclic N-Oxides; Electron Spin Resonance Spectroscopy; Free Radicals; Humans; Kinetics; Nitrates; Oxygen Consumption; Serum Albumin; Spin Labels; Time Factors; Uric Acid | 1996 |
Nitric oxide and peroxynitrite exert distinct effects on mitochondrial respiration which are differentially blocked by glutathione or glucose.
Topics: Animals; Brain; Dithiothreitol; Electron Transport Complex IV; Glucose; Glutathione; Kinetics; Mitochondria; Molsidomine; Nitrates; Nitric Oxide; Oxygen Consumption; Rats; Submitochondrial Particles; Superoxide Dismutase | 1996 |
Acceleration of peroxynitrite oxidations by carbon dioxide.
Topics: Carbon Dioxide; Hydrogen Peroxide; Hydrogen-Ion Concentration; Kinetics; Models, Theoretical; Nitrates; Nitrites; Oxidation-Reduction; Phenols; Time Factors | 1996 |
Peroxynitrite disables the tyrosine phosphorylation regulatory mechanism: Lymphocyte-specific tyrosine kinase fails to phosphorylate nitrated cdc2(6-20)NH2 peptide.
Topics: Amino Acid Sequence; CDC2 Protein Kinase; Cell Cycle; Edetic Acid; Ferric Compounds; In Vitro Techniques; Iron Chelating Agents; Kinetics; Lymphocyte Specific Protein Tyrosine Kinase p56(lck); Molecular Sequence Data; Nitrates; Peptide Fragments; Phosphorylation; Signal Transduction; src-Family Kinases; Tyrosine | 1996 |
Peroxynitrite inhibits glutamate transporter subtypes.
Topics: Amino Acid Transport System X-AG; Animals; ATP-Binding Cassette Transporters; Biological Transport, Active; Brain; Glutamic Acid; HeLa Cells; Humans; In Vitro Techniques; Kinetics; Liposomes; Nitrates; Oxidants; Rats; Recombinant Proteins; Transfection | 1996 |
Characterization of sulfur-centered radical intermediates formed during the oxidation of thiols and sulfite by peroxynitrite. ESR-spin trapping and oxygen uptake studies.
Topics: Cyclic N-Oxides; Electron Spin Resonance Spectroscopy; Formates; Free Radicals; Glutathione; Hydroxyl Radical; In Vitro Techniques; Molecular Structure; Nitrates; Oxidation-Reduction; Penicillamine; Spin Labels; Sulfhydryl Compounds; Sulfites | 1996 |
Peroxynitrite induces airway hyperresponsiveness in guinea pigs in vitro and in vivo.
Topics: Animals; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchoconstriction; Bronchoconstrictor Agents; Dose-Response Relationship, Drug; Drug Resistance; Drug Synergism; Eosinophils; Epithelium; Germ-Free Life; Guinea Pigs; Histamine; Inflammation Mediators; Male; Methacholine Chloride; Mucous Membrane; Nitrates; Time Factors; Trachea | 1996 |
Role of poly-ADP ribosyltransferase activation in the vascular contractile and energetic failure elicited by exogenous and endogenous nitric oxide and peroxynitrite.
Topics: Animals; Interferon-gamma; Lipopolysaccharides; Male; Mice; Mitochondria; Nitrates; Nitric Oxide; Oxygen Consumption; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Rats; Rats, Wistar; Shock, Septic; Superoxides; Uric Acid; Vasoconstriction | 1996 |
O=O NO: it's CO.
Topics: Animals; Brain; Carbon Monoxide Poisoning; Nitrates; Nitric Oxide; Rats; Superoxides | 1996 |
The formation of nitric oxide donors from peroxynitrite.
Topics: Animals; Aorta, Thoracic; Glucose; Half-Life; Humans; Muscle Relaxation; Muscle, Smooth, Vascular; Nitrates; Nitric Oxide; Oxidative Stress; Oxyhemoglobins; Platelet Aggregation Inhibitors; Rabbits; Stereoisomerism | 1995 |
Inactivation of tissue inhibitor of metalloproteinase-1 by peroxynitrite.
Topics: Amino Acid Sequence; Amino Acids; Electrophoresis, Polyacrylamide Gel; Free Radical Scavengers; Glycoproteins; Humans; Kinetics; Matrix Metalloproteinase 3; Metalloendopeptidases; Molecular Sequence Data; Nitrates; Recombinant Proteins; Substrate Specificity; Tissue Inhibitor of Metalloproteinases | 1996 |
Evaluation of the relative contribution of nitric oxide and peroxynitrite to the suppression of mitochondrial respiration in immunostimulated macrophages using a manganese mesoporphyrin superoxide dismutase mimetic and peroxynitrite scavenger.
Topics: Animals; Aorta, Thoracic; Arginine; Cell Line; Diethylamines; Escherichia coli; Free Radical Scavengers; In Vitro Techniques; Kinetics; Lipopolysaccharides; Macrophages; Manganese; Metalloporphyrins; Mitochondria; Muscle, Smooth, Vascular; Nitrates; Nitric Oxide; omega-N-Methylarginine; Oxidation-Reduction; Oxygen Consumption; Penicillamine; Rabbits; S-Nitroso-N-Acetylpenicillamine; Superoxide Dismutase; Vasodilation | 1996 |
Effects of peroxynitrite-induced protein modifications on tyrosine phosphorylation and degradation.
Topics: Animals; Cattle; Endothelium, Vascular; Erythrocytes; Gastrins; Humans; Nitrates; Peptides; Phosphorylation; Plasma; Protein-Tyrosine Kinases; Proteins; Serum Albumin, Bovine; Tyrosine | 1996 |
Differential inhibitory action of nitric oxide and peroxynitrite on mitochondrial electron transport.
Topics: Adenosine Triphosphatases; Animals; Dithionite; Electron Transport; Electron Transport Complex IV; Glutathione; Kinetics; Mitochondria, Heart; NADH Dehydrogenase; Nitrates; Nitric Oxide; Nitroso Compounds; Oxygen Consumption; Penicillamine; Rats; S-Nitroso-N-Acetylpenicillamine; S-Nitrosoglutathione; Succinate Dehydrogenase; Superoxides | 1996 |
Effect of superoxide dismutase mimics on radical adduct formation during the reaction between peroxynitrite and thiols--an ESR-spin trapping study.
Topics: Cyclic N-Oxides; Cysteine; Electron Spin Resonance Spectroscopy; Free Radical Scavengers; Free Radicals; Glutathione; Glutathione Disulfide; Kinetics; Nitrates; Organometallic Compounds; Oxygen; Penicillamine; Spin Labels; Sulfhydryl Compounds; Sulfites; Superoxide Dismutase; Superoxides | 1996 |
Nitric oxide inhibits peroxynitrite-induced production of hydroxyeicosatetraenoic acids and F2-isoprostanes in phosphatidylcholine liposomes.
Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; Animals; Cattle; Dinoprost; Gas Chromatography-Mass Spectrometry; Hydroxyeicosatetraenoic Acids; Lipid Peroxidation; Liposomes; Liver; Nitrates; Nitric Oxide; Oxidation-Reduction; Phosphatidylcholines | 1996 |
Selenium-containing compounds protect DNA from single-strand breaks caused by peroxynitrite.
Topics: Cystine; DNA; DNA Damage; Mannitol; Methionine; Nitrates; Organoselenium Compounds; Plasmids; Selenomethionine; Sulfhydryl Compounds | 1996 |
Exogenous nitric oxide causes collapse of retinal ganglion cell axonal growth cones in vitro.
Topics: Animals; Axons; Cells, Cultured; Cysteine; Free Radical Scavengers; Mercaptoethanol; Molsidomine; Neurites; Nitrates; Nitric Oxide; Nitrites; Nitroprusside; Nitroso Compounds; Penicillamine; Retinal Ganglion Cells; S-Nitroso-N-Acetylpenicillamine; S-Nitrosothiols; Signal Transduction; Sulfhydryl Reagents; Time Factors; Vasodilator Agents; Xenopus laevis | 1996 |
Mechanism of carbon dioxide-catalyzed oxidation of tyrosine by peroxynitrite.
Topics: Carbon Dioxide; Chromatography, High Pressure Liquid; Kinetics; Nitrates; Oxidation-Reduction; Time Factors; Tyrosine | 1996 |
Evidence for superoxide radical production in peroxynitrite decomposition.
Topics: Cyclic N-Oxides; Electron Spin Resonance Spectroscopy; Free Radicals; Nitrates; Oxidation-Reduction; Spin Labels; Spin Trapping; Superoxides | 1995 |
Inducible nitric oxide synthase is present within human atherosclerotic lesions and promotes the formation and activity of peroxynitrite.
Topics: Adult; Aged; Aged, 80 and over; Arteriosclerosis; Biomarkers; Blotting, Western; Female; Foam Cells; Humans; In Situ Hybridization; Macrophages; Male; Middle Aged; Muscle, Smooth, Vascular; Nitrates; Nitric Oxide Synthase; RNA, Messenger; Tyrosine | 1996 |
Nitric oxide synthase generates superoxide and nitric oxide in arginine-depleted cells leading to peroxynitrite-mediated cellular injury.
Topics: Arginine; Cell Line; Enzyme Inhibitors; Humans; L-Lactate Dehydrogenase; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Superoxides | 1996 |
Protection against peroxynitrite dependent tyrosine nitration and alpha 1-antiproteinase inactivation by some anti-inflammatory drugs and by the antibiotic tetracycline.
Topics: Acetaminophen; Aminosalicylic Acids; Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Chromatography, High Pressure Liquid; Enzyme Inhibitors; Flufenamic Acid; Free Radical Scavengers; Humans; Mesalamine; Nitrates; Pancreatic Elastase; Penicillamine; Phenylbutazone; Tetracycline; Tyrosine | 1996 |
DNA strand breakage, activation of poly (ADP-ribose) synthetase, and cellular energy depletion are involved in the cytotoxicity of macrophages and smooth muscle cells exposed to peroxynitrite.
Topics: Adenosine Triphosphate; Animals; Cell Death; Cell Line; DNA Damage; Energy Metabolism; Enzyme Activation; Macrophages; Mice; Mitochondria; Muscle, Smooth; NAD; Nitrates; Poly(ADP-ribose) Polymerases | 1996 |
Peroxynitrite-mediated nitration of tyrosine residues in Escherichia coli glutamine synthetase mimics adenylylation: relevance to signal transduction.
Topics: Cations, Divalent; Escherichia coli; Glutamate-Ammonia Ligase; Manganese; Methionine; Nitrates; Signal Transduction; Structure-Activity Relationship; Tyrosine | 1996 |
Peroxynitrite formation from activated human leukocytes.
Topics: Animals; Arginine; Enzyme Inhibitors; Humans; Luminescent Measurements; Macrophages, Alveolar; Neutrophils; Nitrates; Nitrites; Nitrophenols; omega-N-Methylarginine; Peroxidase; Phenylacetates; Rats; Superoxides; Tetradecanoylphorbol Acetate | 1996 |
Probing the higher order structure of RNA with peroxonitrous acid.
Topics: Animals; Chelating Agents; Edetic Acid; Hydroxyl Radical; Molecular Probes; Molecular Structure; Nitrates; Rabbits; RNA, Fungal; RNA, Transfer; RNA, Transfer, Lys; RNA, Transfer, Phe; Saccharomyces cerevisiae | 1996 |
Peroxynitrite-induced cardiac myocyte injury.
Topics: Analysis of Variance; Animals; Calcium; Cell Membrane; Cells, Cultured; Embryo, Mammalian; Heart; Heart Ventricles; Kinetics; Membrane Fluidity; Mice; Myocardial Contraction; Myocardium; Nitrates; Thiobarbituric Acid Reactive Substances | 1996 |
Reactions of nitric oxide and peroxynitrite with organic molecules and ferrihorseradish peroxidase: interference with the determination of hydrogen peroxide.
Topics: Analysis of Variance; Artifacts; Horseradish Peroxidase; Hydrogen Peroxide; Indicators and Reagents; Kinetics; Nitrates; Nitric Oxide; Nitrogen Oxides; Oxidation-Reduction; Phenylenediamines; Spectrophotometry | 1996 |
Synthesis of peroxynitrite in a two-phase system using isoamyl nitrite and hydrogen peroxide.
Topics: Amyl Nitrite; Chemical Phenomena; Chemistry, Physical; Hydrogen Peroxide; Kinetics; Nitrates; Oxidation-Reduction; Stereoisomerism | 1996 |
The oxidative inactivation of sarcoplasmic reticulum Ca(2+)-ATPase by peroxynitrite.
Topics: Animals; Borohydrides; Calcium-Transporting ATPases; Cysteine; Disulfides; Dithiothreitol; Glutathione; Kinetics; Lipid Peroxidation; Muscle Fibers, Fast-Twitch; Muscle, Skeletal; Nitrates; Oxidation-Reduction; Rabbits; Sarcoplasmic Reticulum; Trypsin | 1996 |
Peroxynitrite mediated oxidation of purine bases of nucleosides and isolated DNA.
Topics: Deoxyadenosines; Deoxyguanosine; DNA; Gamma Rays; Hydroxyl Radical; In Vitro Techniques; Nitrates; Oxidation-Reduction; Purine Nucleosides; Radiation, Ionizing; Reactive Oxygen Species; Solutions; Water | 1996 |
Depletion of brain glutathione results in a decrease of glutathione reductase activity; an enzyme susceptible to oxidative damage.
Topics: Animals; Brain; Brain Chemistry; Buthionine Sulfoximine; Enzyme Inhibitors; gamma-Glutamyltransferase; Glutathione; Glutathione Reductase; In Vitro Techniques; Nerve Tissue Proteins; Nitrates; Oxidative Stress; Rats | 1996 |
Antithrombotic effects of peroxynitrite: inhibition and reversal of aggregation in human platelets.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Diphosphate; Adult; Blood Platelets; Collagen; Cyclic GMP; Humans; Nitrates; Platelet Aggregation; Platelet Aggregation Inhibitors; Prostaglandin Endoperoxides, Synthetic; Spectrophotometry; Thrombin; Thromboxane A2 | 1995 |
Peroxynitrite contributes to the candidacidal activity of nitric oxide-producing macrophages.
Topics: Animals; Antifungal Agents; Candida albicans; Female; Glucans; Macrophages, Peritoneal; Male; Mice; Mice, Inbred BALB C; Nitrates; Nitric Oxide; Opsonin Proteins; Superoxides | 1996 |
Oxidation of vitamin E, vitamin C, and thiols in rat brain synaptosomes by peroxynitrite.
Topics: Animals; Ascorbic Acid; Brain; Dose-Response Relationship, Drug; Humans; Hydrogen-Ion Concentration; Nitrates; Rats; Sulfhydryl Compounds; Synaptosomes; Vitamin E | 1996 |
Enhanced NO production during Mg deficiency and its role in mediating red blood cell glutathione loss.
Topics: Animals; Electron Spin Resonance Spectroscopy; Erythrocytes; Glutathione; Hemoglobins; Magnesium Deficiency; Male; Molsidomine; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley; Weight Gain | 1996 |
Peroxynitrite modulates receptor-activated Ca2+ signaling in vascular endothelial cells.
Topics: Animals; Bradykinin; Calcium; Cattle; Cells, Cultured; Endothelium, Vascular; Inositol 1,4,5-Trisphosphate; Molsidomine; Nitrates; Nitric Oxide; Receptors, Cell Surface; Signal Transduction | 1996 |
Role of peroxynitrite in [3H] gamma-aminobutyric acid release evoked by nitric oxide and its mechanism.
Topics: Animals; Cells, Cultured; Ceruloplasmin; Enzyme Inhibitors; gamma-Aminobutyric Acid; Mice; Mice, Inbred Strains; N-Methylaspartate; Nerve Tissue Proteins; Neurons; Nitrates; Nitric Oxide; Penicillamine; S-Nitroso-N-Acetylpenicillamine; Sodium-Potassium-Exchanging ATPase; Superoxide Dismutase | 1996 |
Induction of nitric oxide synthase inhibits gap junction permeability in cultured rat astrocytes.
Topics: Animals; Astrocytes; Cells, Cultured; Enzyme Induction; Fluorescent Dyes; Gap Junctions; Isoquinolines; Lipopolysaccharides; Nitrates; Nitric Oxide Synthase; omega-N-Methylarginine; Penicillamine; Permeability; Rats; Rats, Wistar; Reactive Oxygen Species; S-Nitroso-N-Acetylpenicillamine; Superoxide Dismutase | 1996 |
Nitrotyrosine residues in placenta. Evidence of peroxynitrite formation and action.
Topics: Adult; Drug Residues; Female; Fetal Growth Retardation; Humans; Immunohistochemistry; Nitrates; Placenta; Pre-Eclampsia; Pregnancy; Tyrosine | 1996 |
Carbon dioxide enhancement of peroxynitrite-mediated protein tyrosine nitration.
Topics: Adult; Animals; Antioxidants; Bicarbonates; Blood Proteins; Carbon Dioxide; Catalysis; Cattle; Humans; Hydrogen-Ion Concentration; In Vitro Techniques; Nitrates; Proteins; Serum Albumin, Bovine; Tyrosine | 1996 |
Peroxynitrite reaction with carbon dioxide/bicarbonate: kinetics and influence on peroxynitrite-mediated oxidations.
Topics: Bicarbonates; Carbon Dioxide; Free Radicals; In Vitro Techniques; Kinetics; Luminescent Measurements; Nitrates; Oxidation-Reduction; Thermodynamics | 1996 |
Modulatory role of nitric oxide on superoxide-dependent luminol chemiluminescence.
Topics: Acridines; Glucose Oxidase; In Vitro Techniques; Luminescent Measurements; Luminol; Models, Chemical; Nitrates; Nitric Oxide; Reactive Oxygen Species; Superoxides; Xanthine Oxidase | 1996 |
Trolox inhibits peroxynitrite-mediated oxidative stress and apoptosis in rat thymocytes.
Topics: Animals; Antioxidants; Apoptosis; Butylated Hydroxyanisole; Butylated Hydroxytoluene; Cells, Cultured; Chromans; DNA; DNA Damage; DNA Repair; DNA-Binding Proteins; Kinetics; Male; Models, Biological; Nitrates; Oxidative Stress; Propofol; Rats; Rats, Sprague-Dawley; T-Lymphocytes; Thiobarbituric Acid Reactive Substances | 1996 |
Colocalization of NOS and SOD1 in neurofilament accumulation within motor neurons of amyotrophic lateral sclerosis: an immunohistochemical study.
Topics: Amyotrophic Lateral Sclerosis; Citrulline; Cyclic GMP; Cytoplasm; Humans; Immunohistochemistry; Motor Neurons; Neurofilament Proteins; Nitrates; Nitric Oxide; Nitrogen; Oxidation-Reduction; Superoxide Dismutase; Tyrosine | 1996 |
Evidence of peroxynitrite involvement in the carrageenan-induced rat paw edema.
Topics: Animals; Carrageenan; Edema; Guanidines; Male; Nitrates; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley; Superoxide Dismutase | 1996 |
Protective effects of tirilazad mesylate in a cellular model of peroxynitrite toxicity.
Topics: Aminoisobutyric Acids; Animals; Biomarkers; Cells, Cultured; Cerebellum; Emulsions; Free Radical Scavengers; Lipid Peroxides; Nitrates; Pregnatrienes; Rats; Rats, Sprague-Dawley; Tyrosine | 1996 |
Sensitivity of human pancreatic islets to peroxynitrite-induced cell dysfunction and death.
Topics: Animals; Cell Death; Cells, Cultured; DNA Damage; Glucose; Humans; Islets of Langerhans; Necrosis; Nitrates; Oxidation-Reduction; Rats; Species Specificity | 1996 |
Expression of inducible nitric oxide synthase and nitrotyrosine in colonic epithelium in inflammatory bowel disease.
Topics: Aged; Aged, 80 and over; Animals; Colon; Diverticulitis, Colonic; Female; Humans; Inflammatory Bowel Diseases; Intestinal Mucosa; Male; Middle Aged; Nitrates; Nitric Oxide Synthase; Rabbits; RNA, Messenger; Tyrosine | 1996 |
Peroxynitrite cytotoxicity on bovine retinal pigmented epithelial cells in culture.
Topics: Animals; Apoptosis; Cattle; Cell Death; Cell Survival; Cells, Cultured; DNA; Dose-Response Relationship, Drug; Free Radical Scavengers; Ginkgo biloba; Immunohistochemistry; Interferon-gamma; Kinetics; Lipopolysaccharides; Nitrates; Nitric Oxide; omega-N-Methylarginine; Pigment Epithelium of Eye; Plant Extracts; Recombinant Proteins | 1996 |
Alterations to glutathione and nicotinamide nucleotides during the mitochondrial permeability transition induced by peroxynitrite.
Topics: Animals; Female; Glutathione; Liver; Mitochondria; Niacinamide; Nitrates; Permeability; Rats; Rats, Wistar | 1996 |
Inhibition of terminal calcium overload protects against peroxynitrite-induced cellular injury in macrophages.
Topics: Aminoquinolines; Animals; Calcium; Cell Line; Cell Survival; Macrophages; Mice; Mitochondria; Nitrates; Respiration | 1996 |
NO synthase and xanthine oxidase activities of rabbit brain synaptosomes: peroxynitrite formation as a causative factor of neurotoxicity.
Topics: Animals; Cell Survival; Cerebral Cortex; Enzyme Inhibitors; Membrane Fluidity; Neurons; Nitrates; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Oxidative Stress; Rabbits; Reactive Oxygen Species; Synaptosomes; Ultraviolet Rays; Xanthine Oxidase | 1996 |
Elevation in arterial blood pressure following the development of tachyphylaxis to peroxynitrite.
Topics: Animals; Blood Pressure; Hindlimb; Male; Nitrates; Rats; Rats, Sprague-Dawley; Tachyphylaxis; Vascular Resistance | 1996 |
Peroxynitrite-dependent tryptophan nitration.
Topics: Deferoxamine; Dimethyl Sulfoxide; Ethanol; Kinetics; Mannitol; Metals; Nitrates; Superoxide Dismutase; Tryptophan | 1996 |
Peroxynitrite reduction of calmodulin stimulation of neuronal nitric oxide synthase.
Topics: Binding, Competitive; Calmodulin; Cytochrome c Group; Down-Regulation; Feedback; Kinetics; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Superoxides | 1996 |
(-)-Epigallocatechin gallate, a polyphenolic tea antioxidant, inhibits peroxynitrite-mediated formation of 8-oxodeoxyguanosine and 3-nitrotyrosine.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Antioxidants; Catechin; Cattle; Deoxyguanosine; DNA; Free Radical Scavengers; Nitrates; Oxidation-Reduction; Tea; Tyrosine | 1996 |
Mechanisms of cerebral vasodilation by superoxide, hydrogen peroxide, and peroxynitrite.
Topics: Aminoquinolines; Animals; Arterioles; Biomechanical Phenomena; Cats; Cerebrovascular Circulation; Enzyme Inhibitors; Glyburide; Hydrogen Peroxide; Nitrates; Superoxides; Tetraethylammonium; Tetraethylammonium Compounds; Vasodilation | 1996 |
Rapid oxidation of DL-selenomethionine by peroxynitrite.
Topics: Chromatography, Gas; Ethylenes; Hydrogen-Ion Concentration; Kinetics; Magnetic Resonance Spectroscopy; Nitrates; Oxidation-Reduction; Selenomethionine | 1996 |
Competitive reactions of peroxynitrite with 2'-deoxyguanosine and 7,8-dihydro-8-oxo-2'-deoxyguanosine (8-oxodG): relevance to the formation of 8-oxodG in DNA exposed to peroxynitrite.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Binding, Competitive; Cattle; Chromatography, High Pressure Liquid; Deoxyguanosine; DNA; DNA Damage; Hydrogen-Ion Concentration; Nitrates; Oxidation-Reduction; Spectrophotometry | 1996 |
Concomitant transcriptional activation of nitric oxide synthase and heme oxygenase genes during nitric oxide-mediated macrophage cytostasis.
Topics: Animals; Binding Sites; Coculture Techniques; Gene Expression Regulation, Enzymologic; Heme Oxygenase (Decyclizing); Interferon-gamma; Leukemia L1210; Lipopolysaccharides; Macrophage Activation; Macrophages, Peritoneal; Mice; Mice, Inbred C3H; NF-kappa B; Nitrates; Nitric Oxide; Nitric Oxide Synthase; RNA, Messenger; Transcriptional Activation; Tumor Cells, Cultured | 1996 |
Involvement of nitric oxide in nitroprusside-induced hepatocyte cytotoxicity.
Topics: Animals; Cell Survival; Cells, Cultured; Lipid Peroxidation; Liver; Male; Nitrates; Nitric Oxide; Nitroprusside; Rats; Rats, Sprague-Dawley | 1996 |
Attenuation of oxidation and nitration reactions of peroxynitrite by selenomethionine, selenocystine and ebselen.
Topics: Azoles; Cystine; Isoindoles; Kinetics; Nitrates; Organoselenium Compounds; Oxidation-Reduction; Phenylacetates; Rhodamines; Selenomethionine | 1996 |
Nitration and inactivation of manganese superoxide dismutase in chronic rejection of human renal allografts.
Topics: Amino Acid Sequence; Analysis of Variance; Blotting, Western; Graft Rejection; Humans; Immunohistochemistry; Kidney; Kidney Transplantation; Models, Biological; Nitrates; Peptide Fragments; Superoxide Dismutase; Transplantation, Homologous; Tyrosine | 1996 |
Nitrotyrosine attenuates the hemodynamic effects of adrenoceptor agonists in vivo: relevance to the pathophysiology of peroxynitrite.
Topics: Adrenergic Agonists; Animals; Arginine Vasopressin; Hemodynamics; Male; Nitrates; Rats; Rats, Sprague-Dawley; Tyrosine | 1996 |
Protection against peroxynitrite-dependent tyrosine nitration and alpha 1-antiproteinase inactivation by ascorbic acid. A comparison with other biological antioxidants.
Topics: alpha 1-Antitrypsin; Antioxidants; Arthritis, Rheumatoid; Ascorbic Acid; Humans; Lipid Peroxidation; Nitrates; Oxidation-Reduction; Oxidative Stress; Pancreatic Elastase; Synovial Fluid; Tyrosine | 1996 |
Fetal growth retardation in rats may result from apoptosis: role of peroxynitrite.
Topics: Animals; Apoptosis; Base Sequence; DNA Primers; Endotoxins; Enzyme Inhibitors; Female; Fetal Growth Retardation; Free Radicals; Gene Expression; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Placenta; Pregnancy; Rats; Uterus | 1996 |
Effect of peroxynitrite on erythrocytes.
Topics: Acetylcholinesterase; Adenosine Triphosphatases; Adult; Cholinesterase Inhibitors; Cyclic N-Oxides; Deferoxamine; Enzyme Inhibitors; Erythrocyte Membrane; Erythrocytes; Glutathione; Hemoglobins; Humans; Lipid Peroxidation; Maleimides; Membrane Lipids; Membrane Proteins; Nitrates; Oxidation-Reduction; Spin Labels; Sulfhydryl Compounds | 1996 |
Involvement of peroxynitrite in the lipid peroxidation induced by nitric oxide in rat gastric mucosa.
Topics: Animals; Dose-Response Relationship, Drug; Enzyme Inhibitors; Gastric Mucosa; Indicators and Reagents; Lipid Peroxidation; Male; Nitrates; Nitric Oxide; Nitroprusside; Penicillamine; Rats; Rats, Wistar; S-Nitroso-N-Acetylpenicillamine; Superoxide Dismutase | 1996 |
Superoxide production by mitochondria in the presence of nitric oxide forms peroxynitrite.
Topics: Animals; Antimycin A; Cattle; Cell Membrane; DNA Damage; DNA, Mitochondrial; Mitochondria, Heart; Nitrates; Nitric Oxide; Oxidative Stress; Superoxides | 1996 |
Measurement of nitric oxide and peroxynitrite generation in the postischemic heart. Evidence for peroxynitrite-mediated reperfusion injury.
Topics: Animals; Electron Spin Resonance Spectroscopy; Enzyme Inhibitors; Female; Immunohistochemistry; Myocardial Contraction; Myocardial Ischemia; Myocardial Reperfusion Injury; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Superoxide Dismutase | 1996 |
Nitric oxide synthase and xanthine oxidase activities in the spermatic vein of patients with varicocele: a potential role for nitric oxide and peroxynitrite in sperm dysfunction.
Topics: Humans; Infertility, Male; Male; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Oxidation-Reduction; Penis; Spermatozoa; Sulfhydryl Compounds; Varicocele; Veins; Xanthine Oxidase | 1996 |
Acidic fibroblast growth factor enhances peroxynitrite-induced apoptosis in primary murine fibroblasts.
Topics: Animals; Apoptosis; Cell Survival; Cells, Cultured; DNA; Drug Synergism; Embryo, Mammalian; Fibroblast Growth Factor 1; Fibroblasts; Hydrogen Peroxide; Kinetics; Mice; Mice, Inbred C57BL; Nitrates; Oxidants; Oxidative Stress; Reactive Oxygen Species; Spermidine | 1996 |
Detection of thiyl radical adducts formed during hydroxyl radical- and peroxynitrite-mediated oxidation of thiols--a high resolution ESR spin-trapping study at Q-band (35 GHz).
Topics: Biological Assay; Free Radicals; Nitrates; Oxidation-Reduction; Spin Trapping; Sulfhydryl Compounds | 1996 |
Role of nitric oxide and its interaction with superoxide in the suppression of cardiac muscle mitochondrial respiration. Involvement in response to hypoxia/reoxygenation.
Topics: Animals; Cattle; Free Radical Scavengers; Hypoxia; Mitochondria, Heart; Nitrates; Nitric Oxide; Osmolar Concentration; Oxygen; Oxygen Consumption; Papillary Muscles; Reactive Oxygen Species; Superoxides | 1996 |
Peroxynitrite augments fMLP-stimulated chemiluminescence by neutrophils in human whole blood.
Topics: Antioxidants; Azides; Benzoquinones; Catalase; Cyclooxygenase Inhibitors; Cytochrome P-450 Enzyme Inhibitors; Dose-Response Relationship, Drug; Drug Synergism; Free Radical Scavengers; Humans; Lipoxygenase Inhibitors; Luminescent Measurements; Luminol; Molsidomine; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Nitrates; Nitric Oxide; omega-N-Methylarginine; Proadifen; Reactive Oxygen Species; Respiratory Burst; Sodium Azide; Superoxide Dismutase; Taurine | 1996 |
DNA damage by peroxynitrite characterized with DNA repair enzymes.
Topics: Butanols; Chromatography, High Pressure Liquid; DNA; DNA Damage; DNA Repair; Endonucleases; Free Radical Scavengers; Hydroxyl Radical; Molsidomine; Nitrates; tert-Butyl Alcohol | 1996 |
Direct and indirect oxidations by peroxynitrite, neither involving the hydroxyl radical.
Topics: Chemical Phenomena; Chemistry; Free Radical Scavengers; Hydroxyl Radical; Kinetics; Models, Chemical; Nitrates; Oxidation-Reduction | 1996 |
Glutathione protects astrocytes from peroxynitrite-mediated mitochondrial damage: implications for neuronal/astrocytic trafficking and neurodegeneration.
Topics: Animals; Astrocytes; Glutathione; Mitochondria; Nerve Degeneration; Neurons; Nitrates; Rats; Rats, Wistar | 1996 |
Mechanism of resistance to NO-induced neurotoxicity in cultured rat dopaminergic neurons.
Topics: 1-Methyl-4-phenylpyridinium; Animals; Antioxidants; Ascorbic Acid; Cell Survival; Cells, Cultured; Dopamine; Drug Resistance; Mesencephalon; Nerve Tissue Proteins; Neurons; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Oxidation-Reduction; Parkinson Disease; Rats; Tyrosine 3-Monooxygenase | 1996 |
Oxidative modification of nicotinamide nucleotide transhydrogenase in submitochondrial particles: effect of endogenous ubiquinol.
Topics: Adenosine Diphosphate; Animals; Ascorbic Acid; Blotting, Western; Cattle; Ferric Compounds; Kinetics; Lipid Peroxides; NAD; NADP; NADP Transhydrogenases; Nitrates; Oxidation-Reduction; Peptide Mapping; Stress, Physiological; Submitochondrial Particles; Tyrosine; Ubiquinone | 1996 |
Reactions of oxymyoglobin with NO, NO2, and NO2- under argon and in air.
Topics: Air; Animals; Argon; Horses; Kinetics; Myocardium; Myoglobin; Nitrates; Nitrogen Dioxide; Nitrous Oxide | 1996 |
Carbon dioxide catalysis of the reaction of peroxynitrite with ethyl acetoacetate: an example of aliphatic nitration by peroxynitrite.
Topics: Acetoacetates; Carbon Dioxide; Nitrates | 1996 |
Taurine attenuates nitric oxide- and reactive oxygen intermediate-dependent hepatocyte injury.
Topics: Animals; Cells, Cultured; Lipopolysaccharides; Liver; Necrosis; Nitrates; Nitric Oxide; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Taurine | 1996 |
Effects of lazaroids and a peroxynitrite scavenger in a cell model of peroxynitrite toxicity.
Topics: Animals; Antioxidants; Cells, Cultured; Cerebellum; Free Radical Scavengers; Models, Biological; Neuroprotective Agents; Nitrates; Pregnatrienes; Pyrimidines; Pyrroles; Pyrrolidines; Pyrrolidinones; Rats; Rats, Sprague-Dawley | 1997 |
Reactive oxygen species produced by macrophage-derived foam cells regulate the activity of vascular matrix metalloproteinases in vitro. Implications for atherosclerotic plaque stability.
Topics: Animals; Aorta; Arteriosclerosis; Cells, Cultured; Coculture Techniques; Collagenases; Diet, Atherogenic; Foam Cells; Gelatinases; Granuloma; Humans; Hydrogen Peroxide; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Metalloendopeptidases; Muscle, Smooth, Vascular; Nitrates; Rabbits; Reactive Oxygen Species; Saphenous Vein | 1996 |
Nitric oxide and peroxynitrite released by ultraviolet B-irradiated human endothelial cells are possibly involved in skin erythema and inflammation.
Topics: Cells, Cultured; Dermatitis; Endothelium, Vascular; Enzyme Activation; Erythema; Humans; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Sunburn; Ultraviolet Rays; Umbilical Veins; Xanthine Oxidase | 1996 |
The peroxynitrite product 3-nitro-L-tyrosine attenuates the hemodynamic responses to angiotensin II in vivo.
Topics: Anesthesia; Angiotensin II; Animals; Hemodynamics; Male; Nitrates; Pentobarbital; Rats; Rats, Sprague-Dawley; Tyrosine; Vasoconstrictor Agents | 1996 |
Pre-exposure to heat shock inhibits peroxynitrite-induced activation of poly(ADP) ribosyltransferase and protects against peroxynitrite cytotoxicity in J774 macrophages.
Topics: Animals; Cells, Cultured; Enzyme Activation; Heat-Shock Proteins; Macrophages; Mice; Mitochondria; Nitrates; Poly(ADP-ribose) Polymerases | 1996 |
Kinetic study of the reaction of ebselen with peroxynitrite.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Azoles; Hydrogen-Ion Concentration; Isoindoles; Kinetics; Nitrates; Organoselenium Compounds; Oxidation-Reduction; Temperature | 1996 |
Formation of oxysterols during oxidation of low density lipoprotein by peroxynitrite, myoglobin, and copper.
Topics: Amidines; Butylated Hydroxytoluene; Copper; Hydroxycholesterols; Ketocholesterols; Lipoproteins, LDL; Molsidomine; Molybdenum; Myoglobin; Nitrates; Oxidation-Reduction; Superoxide Dismutase; Vitamin E | 1996 |
Effects of carbon dioxide/bicarbonate on induction of DNA single-strand breaks and formation of 8-nitroguanine, 8-oxoguanine and base-propenal mediated by peroxynitrite.
Topics: Animals; Bicarbonates; Carbon Dioxide; Cattle; DNA Damage; DNA, Single-Stranded; Guanine; Nitrates; Thymine | 1996 |
Peroxynitrite-induced apoptosis in T84 and RAW 264.7 cells: attenuation by L-ascorbic acid.
Topics: Animals; Apoptosis; Ascorbic Acid; Cell Line; Cell Survival; Culture Media; Epithelium; Free Radical Scavengers; Humans; Intestines; Macrophages; Mice; Necrosis; Nitrates; Trypan Blue | 1997 |
Peroxynitrite, the coupling product of nitric oxide and superoxide, activates prostaglandin biosynthesis.
Topics: Animals; Arachidonic Acid; Cell Line; Enzyme Activation; Glutathione Peroxidase; Kinetics; Macrophages; Metalloporphyrins; Molsidomine; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Salicylates; Superoxides | 1996 |
Formation of nitrosyl hemoglobin and nitrotyrosine during murine leishmaniasis.
Topics: Animals; Disease Models, Animal; Female; Hemoglobins; Leishmania mexicana; Leishmaniasis, Cutaneous; Mice; Mice, Inbred BALB C; Nitrates; Nitric Oxide; Photobiology; Tyrosine | 1996 |
IL-1 beta stimulates superoxide and delayed peroxynitrite production by pulmonary vascular smooth muscle cells.
Topics: Animals; Cells, Cultured; Down-Regulation; Interleukin-1; Lung; Male; Muscle, Smooth, Vascular; Nitrates; Rats; Superoxides; Up-Regulation | 1996 |
Increase of particulate nitric oxide synthase activity and peroxynitrite synthesis in UVB-irradiated keratinocyte membranes.
Topics: Allosteric Regulation; Calcium; Calmodulin; Cell Membrane; Citrulline; Cyclic GMP; Fluorescence Polarization; Guanylate Cyclase; Humans; Keratinocytes; Kinetics; Microsomes; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Reactive Oxygen Species; Temperature; Ultraviolet Rays | 1996 |
Peroxynitrite modification of glutathione reductase: modeling studies and kinetic evidence suggest the modification of tyrosines at the glutathione disulfide binding site.
Topics: Animals; Binding Sites; Blotting, Western; Cattle; Glutathione; Glutathione Reductase; Hydrogen Bonding; Intestinal Mucosa; Kinetics; Models, Molecular; NADP; Nitrates; Protein Binding; Protein Conformation; Solvents; Spectrometry, Fluorescence; Tyrosine | 1996 |
Peroxynitrite inhibition of nitric oxide synthases.
Topics: Animals; Cattle; Cells, Cultured; Citrulline; Endothelium, Vascular; Enzyme Inhibitors; Glutathione; Isoenzymes; Mice; Nitrates; Nitric Oxide Synthase; Swine | 1996 |
Metabolic fate of peroxynitrite in aqueous solution. Reaction with nitric oxide and pH-dependent decomposition to nitrite and oxygen in a 2:1 stoichiometry.
Topics: Hydrogen-Ion Concentration; Kinetics; Nitrates; Nitric Oxide; Nitrites; Oxygen; Solutions; Superoxides; Temperature | 1997 |
Peroxynitrite induces the conversion of xanthine dehydrogenase to oxidase in rabbit liver.
Topics: Animals; Cytosol; Dimethyl Sulfoxide; Dithiothreitol; Dose-Response Relationship, Drug; Free Radical Scavengers; Hydroxyl Radical; Kinetics; Liver; Male; Mannitol; Nitrates; Rabbits; Xanthine Dehydrogenase; Xanthine Oxidase | 1997 |
Prevention of peroxynitrite-dependent tyrosine nitration and inactivation of alpha1-antiproteinase by antibiotics.
Topics: alpha 1-Antitrypsin; Anti-Bacterial Agents; Free Radical Scavengers; Nitrates; Tyrosine | 1997 |
Peroxynitrite-dependent aromatic hydroxylation and nitration of salicylate and phenylalanine. Is hydroxyl radical involved?
Topics: Chromatography, High Pressure Liquid; Free Radical Scavengers; Hydrogen-Ion Concentration; Hydroxyl Radical; Hydroxylation; Nitrates; Phenylalanine; Salicylates; Salicylic Acid | 1997 |
Reactive oxygen species participate in peroxynitrite-induced apoptosis in HL-60 cells.
Topics: Apoptosis; Catalase; DNA, Neoplasm; Free Radical Scavengers; HL-60 Cells; Humans; Hydrogen Peroxide; Kinetics; L-Lactate Dehydrogenase; Luminescent Measurements; Nitrates; Reactive Oxygen Species; Superoxide Dismutase; Superoxides | 1997 |
Quantification of peroxynitrite, superoxide, and peroxyl radicals by a new spin trap hydroxylamine 1-hydroxy-2,2,6,6-tetramethyl-4-oxo-piperidine.
Topics: Amidines; Dimethyl Sulfoxide; Electron Spin Resonance Spectroscopy; Free Radicals; Kinetics; Molsidomine; Nitrates; Peroxides; Piperidines; Reactive Oxygen Species; Spin Labels; Superoxides; Triacetoneamine-N-Oxyl | 1997 |
Peroxynitrite causes energy depletion and increases permeability via activation of poly (ADP-ribose) synthetase in pulmonary epithelial cells.
Topics: Benzamides; Cell Line; Cell Membrane Permeability; Energy Metabolism; Enzyme Activation; Enzyme Inhibitors; Epithelial Cells; Epithelium; Humans; Lung; Nitrates; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases | 1997 |
One-electron oxidation pathway of peroxynitrite decomposition in human blood plasma: evidence for the formation of protein tryptophan-centred radicals.
Topics: Ascorbic Acid; Benzenesulfonates; Bicarbonates; Blood Proteins; Chromatography, Gel; Electron Spin Resonance Spectroscopy; Electron Transport; Free Radicals; Glutathione; Humans; Methionine; Nitrates; Nitroso Compounds; Peptides; Pronase; Spin Trapping; Sulfhydryl Compounds; Tryptophan; Uric Acid | 1997 |
Peroxynitrite-induced tyrosine nitration and phosphorylation in human platelets.
Topics: Blood Platelets; Blood Proteins; Humans; Nitrates; P-Selectin; Phosphorylation; Phosphotyrosine; Platelet Activation; Platelet Aggregation; Serotonin; Thrombin; Tyrosine | 1997 |
Peroxynitrite inhibits leukocyte-endothelial cell interactions and protects against ischemia-reperfusion injury in rats.
Topics: Animals; Aorta, Thoracic; Cell Adhesion; Cell Communication; Endothelium, Vascular; Ileum; Male; Mesenteric Artery, Superior; Microscopy, Video; Muscle Relaxation; Myocardial Reperfusion Injury; Neutrophils; Nitrates; P-Selectin; Rats; Rats, Sprague-Dawley; Venules | 1997 |
Evidence for peroxynitrite as an oxidative stress-inducing compound of aqueous cigarette smoke fractions.
Topics: 3T3 Cells; Animals; Catalase; Enzyme Induction; Gene Expression; Genes, fos; Glutathione; Guanylate Cyclase; Mice; Molsidomine; Nicotiana; Nitrates; Nitric Oxide; Oxidative Stress; Plants, Toxic; Rats; Smoke; Superoxide Dismutase | 1997 |
Nitric oxide activates skeletal and cardiac ryanodine receptors.
Topics: Animals; Calcium; Calcium Channels; Cysteine; Dogs; Free Radicals; Heart Ventricles; Mercaptoethanol; Muscle Proteins; Muscle, Skeletal; Myocardium; Nitrates; Nitric Oxide; Nitroso Compounds; Rabbits; Ryanodine Receptor Calcium Release Channel; S-Nitrosothiols; Sarcoplasmic Reticulum | 1997 |
Inhibition of peroxynitrite-mediated oxidation of glutathione by carbon dioxide.
Topics: Bicarbonates; Carbon Dioxide; Glutathione; Hydrogen-Ion Concentration; Nitrates; Oxidation-Reduction | 1997 |
Melatonin is a scavenger of peroxynitrite.
Topics: Animals; Antioxidants; Cell Line; DNA Damage; DNA, Single-Stranded; Macrophages; Melatonin; Mice; Mitochondria; Nitrates; Oxidation-Reduction; Oxygen Consumption; Rhodamines | 1997 |
Formation of reactive nitrogen species during peroxidase-catalyzed oxidation of nitrite. A potential additional mechanism of nitric oxide-dependent toxicity.
Topics: Catalysis; Free Radicals; Nitrates; Nitric Oxide; Nitrites; Oxidation-Reduction; Peroxidase | 1997 |
Antioxidant action of ergothioneine: assessment of its ability to scavenge peroxynitrite.
Topics: alpha 1-Antitrypsin; Antioxidants; Ergothioneine; Free Radical Scavengers; Nitrates; Tyrosine | 1997 |
Spin trapping of superoxide radicals and peroxynitrite by 1-hydroxy-3-carboxy-pyrrolidine and 1-hydroxy-2,2,6, 6-tetramethyl-4-oxo-piperidine and the stability of corresponding nitroxyl radicals towards biological reductants.
Topics: Animals; Ascorbic Acid; Cysteine; Electron Spin Resonance Spectroscopy; Glutathione; Muscle, Smooth; Nitrates; Oxidation-Reduction; Piperidines; Pyrrolidines; Spin Trapping; Superoxides | 1997 |
Generation of peroxynitrite contributes to ischemia-reperfusion injury in isolated rat hearts.
Topics: Animals; Male; Myocardial Reperfusion Injury; Myocardium; Nitrates; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Penicillamine; Perfusion; Rats; Rats, Sprague-Dawley; S-Nitroso-N-Acetylpenicillamine; Vasodilator Agents | 1997 |
Pathways of peroxynitrite oxidation of thiol groups.
Topics: Catalase; Cysteine; Electron Spin Resonance Spectroscopy; Free Radical Scavengers; Glutathione; Kinetics; Nitrates; Oxidation-Reduction; Oxygen Consumption; Sulfhydryl Compounds; Superoxide Dismutase | 1997 |
Mercaptoethylguanidine and guanidine inhibitors of nitric-oxide synthase react with peroxynitrite and protect against peroxynitrite-induced oxidative damage.
Topics: Animals; Cell Line; Enzyme Inhibitors; Guanidines; Kinetics; Models, Chemical; Muscle Contraction; Muscle, Smooth, Vascular; Nitrates; Nitric Oxide Synthase; Norepinephrine; Oxidation-Reduction; Oxygen Consumption; Rats; Vasoconstrictor Agents | 1997 |
Peroxynitrite impairs cardiac contractile function by decreasing cardiac efficiency.
Topics: Adenosine Triphosphate; Analysis of Variance; Animals; Energy Metabolism; Glucose; Glycolysis; Heart; In Vitro Techniques; Kinetics; Male; Myocardial Contraction; Myocardium; NAD; Nitrates; Oxygen Consumption; Penicillamine; Perfusion; Phosphocreatine; Pyruvates; Rats; Rats, Sprague-Dawley; S-Nitroso-N-Acetylpenicillamine | 1997 |
Widespread peroxynitrite-mediated damage in Alzheimer's disease.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Cerebral Cortex; Entorhinal Cortex; Hippocampus; Humans; Immunohistochemistry; Middle Aged; Neurons; Nitrates; Oxidative Stress; Tyrosine | 1997 |
Inflammation and NO(X)-induced nitration: assay for 3-nitrotyrosine by HPLC with electrochemical detection.
Topics: Animals; Blood Proteins; Cell Line; Chromatography, High Pressure Liquid; Electrochemistry; Gas Chromatography-Mass Spectrometry; Inflammation; Macrophage Activation; Male; Nitrates; Nitric Oxide; Rats; Rats, Inbred F344; Tyrosine; Zymosan | 1997 |
gamma-tocopherol traps mutagenic electrophiles such as NO(X) and complements alpha-tocopherol: physiological implications.
Topics: Antioxidants; Free Radical Scavengers; Humans; Isomerism; Lipid Peroxidation; Lipoproteins, LDL; Mutagens; Nitrates; Vitamin E | 1997 |
Thiourea and dimethylthiourea inhibit peroxynitrite-dependent damage: nonspecificity as hydroxyl radical scavengers.
Topics: alpha 1-Antitrypsin; Enzyme Inhibitors; Free Radical Scavengers; Hydroxyl Radical; Nitrates; Thiourea; Tyrosine | 1997 |
Peroxynitrite inhibits glutathione S-conjugate transport.
Topics: Biological Transport; Bridged Bicyclo Compounds; Dose-Response Relationship, Drug; Erythrocytes; Glutathione; Humans; Nitrates | 1997 |
Superoxide modulates the oxidation and nitrosation of thiols by nitric oxide-derived reactive intermediates. Chemical aspects involved in the balance between oxidative and nitrosative stress.
Topics: Free Radicals; Glutathione; Glutathione Disulfide; Hydrazines; Models, Chemical; Nitrates; Nitric Oxide; Nitrogen Oxides; Nitroso Compounds; Oxidation-Reduction; S-Nitrosoglutathione; Sulfhydryl Compounds; Superoxides; Triazoles; Xanthine Oxidase | 1997 |
Investigation of role for oxidant stress in vascular tolerance development to glyceryl trinitrate in vitro.
Topics: Animals; Aorta; Free Radical Scavengers; In Vitro Techniques; Male; Nitrates; Nitroglycerin; Oxidative Stress; Rats; Rats, Wistar; Superoxides; Vasodilator Agents | 1997 |
Quantitation of 8-oxoguanine and strand breaks produced by four oxidizing agents.
Topics: Copper; DNA; DNA Adducts; Edetic Acid; Ferrous Compounds; Gamma Rays; Guanine; Nitrates; Oxidants; Oxidative Stress | 1997 |
Reactions of peroxynitrite with gamma-tocopherol.
Topics: Magnetic Resonance Spectroscopy; Molsidomine; Nitrates; Oxidation-Reduction; Spectrophotometry, Ultraviolet; Vitamin E | 1997 |
The potential role of peroxynitrite in the vascular contractile and cellular energetic failure in endotoxic shock.
Topics: Animals; Cells, Cultured; Lipopolysaccharides; Male; Metalloporphyrins; Mice; Mitochondria; Muscle, Smooth, Vascular; Nitrates; Nitric Oxide; Oxygen Consumption; Rats; Rats, Wistar; Shock, Septic; Vasoconstriction | 1997 |
beta-Carotene effectively scavenges toxic nitrogen oxides: nitrogen dioxide and peroxynitrous acid.
Topics: Amiloride; Ascorbic Acid; beta Carotene; Docosahexaenoic Acids; Electron Spin Resonance Spectroscopy; Free Radical Scavengers; Nitrates; Nitrogen Dioxide; Vitamin E | 1997 |
Clinical evidence of peroxynitrite formation in chronic renal failure patients with septic shock.
Topics: Adult; Aged; Aged, 80 and over; Case-Control Studies; Female; Free Radicals; Humans; Kidney Failure, Chronic; Male; Middle Aged; Nitrates; Nitric Oxide; Shock, Septic; Superoxides; Tyrosine | 1997 |
Interference of carboxy-PTIO with nitric oxide- and peroxynitrite-mediated reactions.
Topics: Animals; Benzoates; Cattle; Cells, Cultured; Cyclic GMP; Endothelium, Vascular; Free Radical Scavengers; Imidazoles; Kinetics; Molsidomine; Nitrates; Nitric Oxide; Nitrites; Serum Albumin, Bovine; Swine; Tyrosine | 1997 |
Prevention of experimental allergic encephalomyelitis by targeting nitric oxide and peroxynitrite: implications for the treatment of multiple sclerosis.
Topics: Animals; Brain; Bridged-Ring Compounds; Cyclic N-Oxides; Encephalomyelitis, Autoimmune, Experimental; Enzyme Induction; Female; Free Radical Scavengers; Humans; Imidazoles; Mice; Mice, Inbred Strains; Monocytes; Multiple Sclerosis; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Norbornanes; Polymerase Chain Reaction; RNA, Messenger; Spinal Cord; Thiocarbamates; Thiones; Transcription, Genetic; Uric Acid | 1997 |
Inhibition of peroxynitrite-mediated tyrosine nitration by catechin polyphenols.
Topics: Catechin; Free Radical Scavengers; Humans; Lipoproteins, LDL; Nitrates; Reference Standards; Tyrosine | 1997 |
Nitrotyrosine bound to beta-VLDL-apoproteins: a biomarker of peroxynitrite formation in experimental atherosclerosis.
Topics: Animals; Arteriosclerosis; Biomarkers; Blood Proteins; Cholesterol; Hypercholesterolemia; Lipoproteins, VLDL; Male; Nitrates; Rabbits; Triglycerides; Tyrosine | 1997 |
Development of autoimmune diabetes in NOD mice is associated with the formation of peroxynitrite in pancreatic islet beta-cells.
Topics: Animals; Cell Count; Diabetes Mellitus, Type 1; Female; Islets of Langerhans; Leukocytes; Macrophages; Mice; Mice, Inbred BALB C; Mice, Inbred NOD; Nitrates; Tyrosine | 1997 |
Release of glutathione from erythrocytes and other markers of oxidative stress in carbon monoxide poisoning.
Topics: Animals; Biological Transport; Biomarkers; Blood Platelets; Carbon Monoxide Poisoning; Cytochalasin B; Enzyme Inhibitors; Erythrocyte Count; Erythrocyte Membrane; Erythrocytes; Glutathione; Glutathione Disulfide; Hexoses; Male; Molsidomine; Neutrophils; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Oxidative Stress; Rats; Rats, Wistar; Thiobarbituric Acid Reactive Substances | 1997 |
Propofol is a peroxynitrite scavenger.
Topics: Anesthetics, Intravenous; Antioxidants; Free Radical Scavengers; Lipid Peroxidation; Luminescent Measurements; Nitrates; Propofol | 1997 |
3-Morpholino-sydnonimine-induced suppression of human neutrophil degranulation is not mediated by cyclic GMP, nitric oxide or peroxynitrite: inhibition of the increase in intracellular free calcium concentration by N-morpholino-iminoacetonitrile, a metabo
Topics: Acetonitriles; Calcium; Cell Degranulation; Cyclic GMP; Humans; Molsidomine; Morpholines; Neutrophils; Nitrates; Nitric Oxide | 1997 |
Increased production of the potent oxidant peroxynitrite in the lungs of patients with idiopathic pulmonary fibrosis.
Topics: Endothelium, Vascular; Epithelium; Female; Humans; Immunohistochemistry; In Situ Hybridization; Lung; Macrophages, Alveolar; Male; Middle Aged; Nitrates; Oxidants; Pulmonary Fibrosis; Tyrosine | 1997 |
Oxygen-dependent fragmentation of cellular DNA by nitric oxide.
Topics: Adenosine Triphosphate; Apoptosis; Benzoates; Benzoquinones; DNA Fragmentation; Enzyme Inhibitors; Free Radicals; HL-60 Cells; Humans; Imidazoles; Lactams, Macrocyclic; Nitrates; Nitric Oxide; Nitrites; Nitroso Compounds; Oxygen; Quinones; Reactive Oxygen Species; Rifabutin | 1997 |
Inactivation of the inducible nitric oxide synthase by peroxynitrite.
Topics: Amino Acid Sequence; Animals; Calmodulin; Cell Line, Transformed; Dose-Response Relationship, Drug; Enzyme Induction; Humans; Infusion Pumps; Liver; Melitten; Mice; Molecular Sequence Data; Nitrates; Nitric Oxide Synthase; Oxidation-Reduction; Spectrum Analysis | 1997 |
Hypercholesterolemia impairs a detoxification mechanism against peroxynitrite and renders the vascular tissue more susceptible to oxidative injury.
Topics: Animals; Aorta; Blood Vessels; Glutathione; Hypercholesterolemia; In Vitro Techniques; Inactivation, Metabolic; Male; Nitrates; Nitric Oxide; Rabbits; Vasodilation | 1997 |
Oxidative modification of tryptophan residues exposed to peroxynitrite.
Topics: Animals; Cattle; Chromatography, High Pressure Liquid; Collagen; Humans; Indoles; Kynurenine; Molecular Structure; Nitrates; Oxidation-Reduction; Placenta; Serum Albumin, Bovine; Spectrometry, Fluorescence; Tryptophan | 1997 |
Degradation of hyaluronan by peroxynitrite.
Topics: Benzoates; Benzoic Acid; Dimethyl Sulfoxide; Electrophoresis, Agar Gel; Hyaluronic Acid; Hydroxyl Radical; Mannitol; Molecular Weight; Nitrates; Thiourea; Viscosity | 1997 |
The mechanism of apolipoprotein B-100 thiol depletion during oxidative modification of low-density lipoprotein.
Topics: Antioxidants; Apolipoprotein B-100; Apolipoproteins B; Copper; Cyclic N-Oxides; Electron Spin Resonance Spectroscopy; Kinetics; Lipid Peroxidation; Lipoproteins, LDL; Nitrates; Nitrogen Oxides; Oxidation-Reduction; Pyridines; Spin Labels; Sulfhydryl Compounds; Sulfhydryl Reagents; Vitamin E | 1997 |
Formation of nitric oxide, superoxide, and peroxynitrite in myocardial ischemia-reperfusion injury in rats.
Topics: Animals; Arrhythmias, Cardiac; Creatine Kinase; Inflammation; Lung; Male; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocardium; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Peroxidase; Rats; Rats, Sprague-Dawley; Superoxides | 1997 |
Characterization of the vasodilator properties of peroxynitrite on rat pulmonary artery: role of poly (adenosine 5'-diphosphoribose) synthase.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Dose-Response Relationship, Drug; In Vitro Techniques; Male; NG-Nitroarginine Methyl Ester; Nitrates; Poly(ADP-ribose) Polymerases; Prostaglandin Endoperoxides, Synthetic; Pulmonary Artery; Rats; Rats, Wistar; Thromboxane A2; Vasodilation; Vasodilator Agents | 1997 |
Aseptic loosening of total hip replacement. Macrophage expression of inducible nitric oxide synthase and cyclo-oxygenase-2, together with peroxynitrite formation, as a possible mechanism for early prosthesis failure.
Topics: Adolescent; Adult; Aged; Cyclooxygenase 2; Dinoprostone; Enzyme Induction; Female; Hip Prosthesis; Humans; Immunohistochemistry; Isoenzymes; Macrophages; Male; Membrane Proteins; Middle Aged; Nitrates; Nitric Oxide Synthase; Prostaglandin-Endoperoxide Synthases; Prosthesis Failure; Reoperation; Time Factors | 1997 |
The possible role of peroxynitrite in Alzheimer's disease: a simple hypothesis that could be tested more thoroughly.
Topics: Alzheimer Disease; Amyloid beta-Protein Precursor; Anti-Inflammatory Agents; Antioxidants; Humans; Inflammation; Microglia; Models, Biological; NF-kappa B; Nitrates; Protein Denaturation | 1997 |
Nitric oxide synergistically enhances DNA strand breakage induced by polyhydroxyaromatic compounds, but inhibits that induced by the Fenton reaction.
Topics: Catechols; Copper; DNA Damage; Drug Synergism; Hydrogen Peroxide; Hydroquinones; Iron; Molsidomine; Nitrates; Nitric Oxide; Plasmids; Reactive Oxygen Species | 1997 |
Activation of human neutrophil procollagenase by nitrogen dioxide and peroxynitrite: a novel mechanism for procollagenase activation involving nitric oxide.
Topics: alpha 1-Antitrypsin; Benzoates; Collagen; Collagenases; Edetic Acid; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Enzyme Precursors; Humans; Imidazoles; Leukocyte Elastase; Matrix Metalloproteinase 8; Methemoglobin; Neutrophils; Nitrates; Nitric Oxide; Nitrogen Dioxide; Oxyhemoglobins; Phenanthrolines; Tetradecanoylphorbol Acetate; Triazines | 1997 |
Free and protein-associated nitrotyrosine formation following rat liver preservation and transplantation.
Topics: Animals; Chromatography, High Pressure Liquid; Electrochemistry; Free Radicals; Humans; Liver; Liver Transplantation; Nitrates; Organ Preservation; Protein Binding; Rats; Rats, Sprague-Dawley; Time Factors; Tyrosine | 1997 |
Extensive tyrosine nitration in human myocardial inflammation: evidence for the presence of peroxynitrite.
Topics: Adolescent; Autopsy; Child; Child, Preschool; Densitometry; Female; Humans; Infant; Infant, Newborn; Male; Myocarditis; Nitrates; Nitrosation; Retrospective Studies; Sepsis; Tyrosine | 1997 |
Peroxynitrite and oxidative damage in experimental autoimmune uveitis.
Topics: Animals; Arrestin; Autoimmune Diseases; Disease Models, Animal; Female; Fluorescent Antibody Technique, Indirect; Lipid Peroxidation; Lipid Peroxides; Membrane Lipids; Nitrates; Oxidative Stress; Rabbits; Rats; Rats, Inbred Lew; Retina; Rhodamines; Specific Pathogen-Free Organisms; Uveitis | 1997 |
Superoxide and peroxynitrite generation from inducible nitric oxide synthase in macrophages.
Topics: Animals; Cell Line; Chromatography, High Pressure Liquid; Electron Spin Resonance Spectroscopy; Macrophages; Mice; Nitrates; Nitric Oxide Synthase; Superoxides | 1997 |
The catalytic role of carbon dioxide in the decomposition of peroxynitrite.
Topics: Carbon Dioxide; Catalysis; Computer Simulation; Free Radicals; Hydrogen-Ion Concentration; In Vitro Techniques; Kinetics; Models, Chemical; Nitrates | 1997 |
Nitric oxide trapping of the tyrosyl radical of prostaglandin H synthase-2 leads to tyrosine iminoxyl radical and nitrotyrosine formation.
Topics: Arachidonic Acid; Blotting, Western; Electron Spin Resonance Spectroscopy; Free Radicals; Humans; Hydrazines; Mutagens; Nitrates; Nitric Oxide; Nitrogen Oxides; Prostaglandin-Endoperoxide Synthases; Superoxide Dismutase; Tyrosine | 1997 |
Endogenously produced peroxynitrite induces the oxidation of mitochondrial and nuclear proteins in immunostimulated macrophages.
Topics: Adjuvants, Immunologic; Animals; Cell Line; Interferon-gamma; Lipopolysaccharides; Macrophages; Mice; Mitochondria; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide Synthase; Nuclear Proteins; Oxidation-Reduction; Subcellular Fractions; Superoxide Dismutase | 1997 |
Antioxidant activity of polyphenolics in diets. Rate constants of reactions of chlorogenic acid and caffeic acid with reactive species of oxygen and nitrogen.
Topics: Antioxidants; Caffeic Acids; Chlorogenic Acid; Diet; Flavonoids; Free Radical Scavengers; Hydroxides; Nitrates; Peroxides; Phenols; Polymers; Polyphenols; Reactive Oxygen Species | 1997 |
Nerve growth factor protects PC12 cells against peroxynitrite-induced apoptosis via a mechanism dependent on phosphatidylinositol 3-kinase.
Topics: Animals; Apoptosis; Chromones; Enzyme Inhibitors; Morpholines; Mutation; Nerve Growth Factors; Neuroprotective Agents; Nitrates; PC12 Cells; Phosphatidylinositol 3-Kinases; Phosphotransferases (Alcohol Group Acceptor); Precipitin Tests; Proto-Oncogene Proteins p21(ras); Rats | 1997 |
Flavone acetic acid stimulates nitric oxide and peroxynitrite production in subcutaneous mouse tumors.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Apoptosis; Calcium; Cell Division; Cell Line, Transformed; Flavonoids; Free Radicals; Kinetics; Mice; Mice, Nude; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Time Factors | 1997 |
Extensive peroxynitrite activity during progressive stages of central nervous system inflammation.
Topics: Animals; Antibody Specificity; Brain; Disease Progression; Encephalomyelitis, Autoimmune, Experimental; Free Radicals; Immunohistochemistry; Lipid Peroxidation; Mice; Mice, Inbred Strains; Neuritis, Autoimmune, Experimental; Neurons; Nitrates; Nitric Oxide; Spinal Cord; Staining and Labeling; Tyrosine | 1997 |
Decrease in accessible thiols as an index of oxidative damage to membrane proteins.
Topics: Adult; Amidines; Cyclic N-Oxides; Dithionitrobenzoic Acid; Electron Spin Resonance Spectroscopy; Erythrocyte Membrane; Gamma Rays; Humans; Hydrogen Peroxide; Membrane Proteins; Nitrates; Oxidants; Oxidative Stress; Peroxides; Spin Labels; Sulfhydryl Compounds; tert-Butylhydroperoxide; Vitamin K | 1997 |
Thiol compounds interact with nitric oxide in regulating heme oxygenase-1 induction in endothelial cells. Involvement of superoxide and peroxynitrite anions.
Topics: Acetylcysteine; Animals; Aorta; Buthionine Sulfoximine; Cattle; Cells, Cultured; Endothelium, Vascular; Enzyme Activation; Enzyme Induction; Glutathione; Heme Oxygenase (Decyclizing); Heme Oxygenase-1; Humans; Kinetics; Membrane Proteins; Nitrates; Nitric Oxide; Nitrites; Nitroprusside; Penicillamine; S-Nitroso-N-Acetylpenicillamine; Sulfhydryl Compounds; Superoxides; Umbilical Veins | 1997 |
Synergistic induction of DNA strand breakage by cigarette tar and nitric oxide.
Topics: Copper; DNA Damage; DNA, Single-Stranded; Drug Synergism; Free Radical Scavengers; Nicotiana; Nitrates; Nitric Oxide; Plants, Toxic; Tars | 1997 |
The oxidation of selenocysteine is involved in the inactivation of glutathione peroxidase by nitric oxide donor.
Topics: Amino Acid Sequence; Apoptosis; Glutathione Peroxidase; Molecular Sequence Data; Molsidomine; Nitrates; Nitric Oxide; Nitroprusside; Oxidation-Reduction; Selenocysteine | 1997 |
Endothelial dysfunction in a rat model of endotoxic shock. Importance of the activation of poly (ADP-ribose) synthetase by peroxynitrite.
Topics: Animals; Cells, Cultured; Endothelium, Vascular; Enzyme Activation; Humans; Lipopolysaccharides; Mice; Nitrates; Poly(ADP-ribose) Polymerases; Rats; Shock, Septic | 1997 |
Peroxynitrite and nitric oxide donors induce neuronal apoptosis by eliciting autocrine excitotoxicity.
Topics: Animals; Apoptosis; Calcium; Cell Differentiation; Cerebellum; Cysteine; Hormones; Intracellular Membranes; Mice; Neurons; Neurotoxins; Nitrates; Nitric Oxide; Osmolar Concentration; Receptors, N-Methyl-D-Aspartate; S-Nitrosothiols | 1997 |
Redox modulation of iron regulatory proteins by peroxynitrite.
Topics: Aconitate Hydratase; Animals; Cells, Cultured; Cysteine; Ferritins; Humans; Iron Regulatory Protein 1; Iron Regulatory Protein 2; Iron-Regulatory Proteins; Iron-Sulfur Proteins; Mercaptoethanol; Mice; Models, Chemical; Molsidomine; Nitrates; Nitric Oxide; Oxidation-Reduction; Point Mutation; Protein Processing, Post-Translational; Recombinant Proteins; RNA-Binding Proteins; RNA, Messenger | 1997 |
Peroxynitrite scavenging by flavonoids.
Topics: Flavonoids; Free Radical Scavengers; Hydroxylation; Molecular Structure; Nitrates; Quercetin; Rutin; Structure-Activity Relationship | 1997 |
Beneficial effects of 3-aminobenzamide, an inhibitor of poly (ADP-ribose) synthetase in a rat model of splanchnic artery occlusion and reperfusion.
Topics: Animals; Benzamides; Blood Pressure; Cell Membrane Permeability; Enzyme Activation; Enzyme Inhibitors; In Vitro Techniques; Intestines; Male; Mesenteric Arteries; Mesenteric Vascular Occlusion; Models, Biological; Nitrates; Nitric Oxide; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Survival Rate | 1997 |
Peroxynitrite-mediated decarboxylation of pyruvate to both carbon dioxide and carbon dioxide radical anion.
Topics: Anions; Carbon Dioxide; Chromatography, Ion Exchange; Decarboxylation; Electron Spin Resonance Spectroscopy; Free Radicals; Kinetics; Nitrates; Oxidants; Oxygen Consumption; Pyruvic Acid | 1997 |
Toxicity of peroxynitrite and related reactive nitrogen species toward Escherichia coli.
Topics: Escherichia coli; Free Radicals; Hydrogen Peroxide; Kinetics; Lethal Dose 50; Nitrates; Nitroso Compounds; Oxidants | 1997 |
Immunohistochemical localization of nitric oxide synthase and the oxidant peroxynitrite in lung transplant recipients with obliterative bronchiolitis.
Topics: Bronchiolitis Obliterans; Endothelium, Vascular; Humans; Immunohistochemistry; Lung; Lung Transplantation; Macrophages, Alveolar; Nitrates; Nitric Oxide Synthase | 1997 |
Inhibition of astrocyte glutamate uptake by reactive oxygen species: role of antioxidant enzymes.
Topics: Animals; Animals, Newborn; Antioxidants; Ascorbic Acid; Astrocytes; Catalase; Free Radical Scavengers; Glutamic Acid; Glutathione Peroxidase; Hydrogen Peroxide; Mice; Mice, Inbred C57BL; Nitrates; Nitric Oxide; Reactive Oxygen Species; Superoxides; Thiourea | 1997 |
The effect of nitric oxide release rates on the oxidation of human low density lipoprotein.
Topics: Amidines; Copper; Free Radicals; Humans; Kinetics; Lipid Peroxides; Lipoproteins, LDL; Nitrates; Nitric Oxide; Oxidation-Reduction; Vitamin E | 1997 |
Nitric oxide, perioxynitrite and poly(ADP-ribose) synthetase in anaphylactic shock.
Topics: Anaphylaxis; Animals; Nitrates; Nitric Oxide; Poly Adenosine Diphosphate Ribose | 1997 |
Peroxynitrite-mediated nitration of peptides: characterization of the products by electrospray and combined gas chromatography-mass spectrometry.
Topics: Chromatography, Liquid; Enkephalin, Leucine; Gas Chromatography-Mass Spectrometry; Hemoglobins; HIV Envelope Protein gp120; Mass Spectrometry; Nitrates; Peptide Fragments; Trimethylsilyl Compounds; Tyrosine | 1997 |
Biological reactions of peroxynitrite: evidence for an alternative pathway of salicylate hydroxylation.
Topics: Chromatography, High Pressure Liquid; Electron Spin Resonance Spectroscopy; Hydroxylation; Nitrates; Reactive Oxygen Species; Salicylates; Salicylic Acid | 1997 |
Oxidation of cholesterol in synaptosomes and mitochondria isolated from rat brains.
Topics: Animals; Antioxidants; Ascorbic Acid; Borohydrides; Brain; Chelating Agents; Cholesterol; Chromatography, Gas; Ferrous Compounds; Male; Mitochondria; Nitrates; Oxidation-Reduction; Oxidative Stress; Rats; Rats, Inbred F344; Synaptosomes; Vitamin E | 1997 |
Direct ESR detection or peroxynitrite-induced tyrosine-centred protein radicals in human blood plasma.
Topics: Amino Acid Sequence; Ascorbic Acid; Electron Spin Resonance Spectroscopy; Free Radicals; Humans; Molecular Sequence Data; Nitrates; Sulfhydryl Compounds; Tyrosine; Uric Acid | 1997 |
What nitrates tyrosine? Is nitrotyrosine specific as a biomarker of peroxynitrite formation in vivo?
Topics: Biomarkers; Free Radicals; Humans; Molecular Structure; Nitrates; Nitric Oxide; Nitrogen Dioxide; Nitrous Acid; Peroxidase; Superoxides; Tyrosine | 1997 |
NO elicits prolonged relaxation of bovine pulmonary arteries via endogenous peroxynitrite generation.
Topics: Animals; Cattle; Luminescent Measurements; Nitrates; Nitric Oxide; Potassium Chloride; Pulmonary Artery; Sulfhydryl Compounds; Superoxides; Time Factors; Vasodilation | 1997 |
Effects of reactive metabolites of oxygen and nitrogen on gelatinase A activity.
Topics: Animals; Enzyme Inhibitors; Fibroblasts; Gelatinases; Lung; Matrix Metalloproteinase 2; Metalloendopeptidases; Nitrates; Nitric Oxide; Nitrogen; Oxygen; Rats; Superoxides | 1997 |
Tyrosine nitration as a mechanism of selective inactivation of prostacyclin synthase by peroxynitrite.
Topics: Animals; Cattle; Cell Line; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Endothelium, Vascular; Humans; Intramolecular Oxidoreductases; Nitrates; Nitric Oxide; Superoxides; Tyrosine | 1997 |
Peroxynitrite-induced hemolysis of human erythrocytes and its inhibition by antioxidants.
Topics: Acetylcysteine; Albumins; Amidines; Antioxidants; Azoles; Catalase; Chromans; Erythrocytes; Glutathione; Hematocrit; Hemolysis; Humans; Isoindoles; Molsidomine; Nitrates; Organoselenium Compounds; Uric Acid; Vitamin E | 1997 |
Prostaglandin E2 synthesis is differentially affected by reactive nitrogen intermediates in cultured rat microglia and RAW 264.7 cells.
Topics: Animals; Arachidonic Acid; Cells, Cultured; Cerebral Cortex; Cyclooxygenase 2; Dinoprostone; Enzyme Inhibitors; Isoenzymes; Lipopolysaccharides; Macrophages; Mice; Microglia; Molsidomine; Nitrates; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Penicillamine; Prostaglandin-Endoperoxide Synthases; Rats; S-Nitroso-N-Acetylpenicillamine | 1997 |
Carbon dioxide modulation of hydroxylation and nitration of phenol by peroxynitrite.
Topics: Carbon Dioxide; Hydrogen-Ion Concentration; Hydroxylation; Kinetics; Nitrates; Nitrophenols; Phenol; Phenols | 1997 |
Oxidative DNA damage in the parkinsonian brain: an apparent selective increase in 8-hydroxyguanine levels in substantia nigra.
Topics: Aged; Aged, 80 and over; Aging; Base Composition; DNA; DNA Damage; Gas Chromatography-Mass Spectrometry; Guanine; Humans; Hydroxyl Radical; Middle Aged; Nitrates; Oxidants; Oxidation-Reduction; Parkinson Disease; Pyrimidines; Reference Values; Regression Analysis; Substantia Nigra | 1997 |
Nitric oxide-induced hyperpermeability of human intestinal epithelial monolayers is augmented by inhibition of the amiloride-sensitive Na(+)-H+ antiport: potential role of peroxynitrous acid.
Topics: Amiloride; Cell Membrane Permeability; Colonic Neoplasms; Deferoxamine; Humans; Intestinal Mucosa; Membrane Potentials; Molsidomine; Nitrates; Nitric Oxide; Nitrous Acid; Peroxynitrous Acid; Sodium-Hydrogen Exchangers; Superoxides; Tumor Cells, Cultured | 1997 |
Bcl-2 blocks peroxynitrite-induced apoptosis in HL-60 cells, an association with reactive oxygen species.
Topics: Apoptosis; Glutathione; HL-60 Cells; Humans; Nitrates; Proto-Oncogene Proteins c-bcl-2; Reactive Oxygen Species | 1997 |
Protection by inhibition of poly (ADP-ribose) synthetase against oxidant injury in cardiac myoblasts In vitro.
Topics: Animals; Cell Hypoxia; Cells, Cultured; Enzyme Activation; Hydrogen Peroxide; Mice; Mitochondria, Heart; Myocardium; Nitrates; Nitric Oxide; Oxidants; Oxidative Stress; Poly(ADP-ribose) Polymerase Inhibitors; Rats | 1997 |
Vascular endothelial cells generate peroxynitrite in response to carbon monoxide exposure.
Topics: Animals; Arginine; Carbon Monoxide; Cattle; Cell Survival; Cells, Cultured; Chromium; Endothelium, Vascular; Nitrates; Nitric Oxide Synthase; Nitrites; Oxidants; Oxidation-Reduction; Oxygen Consumption; Sulfhydryl Compounds; Tetrazolium Salts; Thiazoles; Tyrosine | 1997 |
Ca2+-independent permeabilization of the inner mitochondrial membrane by peroxynitrite is mediated by membrane protein thiol cross-linking and lipid peroxidation.
Topics: Animals; Calcium; Cross-Linking Reagents; Female; Intracellular Membranes; Lipid Peroxidation; Membrane Potentials; Mitochondria, Liver; Nitrates; Oxidants; Permeability; Rats; Rats, Wistar; Sulfhydryl Compounds; Thiobarbituric Acid Reactive Substances | 1997 |
Induction of stress proteins by tobacco smoke in human monocytes: modulation by antioxidants.
Topics: Adult; Antioxidants; Female; Heat-Shock Proteins; Humans; Hydroxyl Radical; Male; Middle Aged; Monocytes; Nitrates; Nitric Oxide; Reactive Oxygen Species; Tobacco Smoke Pollution | 1997 |
Peroxynitrite. An apoptotic agent in HL-60 cells.
Topics: Apoptosis; Cell Division; DNA Fragmentation; Glutathione; HL-60 Cells; Humans; Inflammation; Nitrates; Nitric Oxide; Nitroso Compounds; S-Nitrosoglutathione; Superoxides | 1997 |
Thiols and disulphides can aggravate peroxynitrite-dependent inactivation of alpha1-antiproteinase.
Topics: alpha 1-Antitrypsin; Disulfides; Enzyme Activation; Hypochlorous Acid; Nitrates; Sulfhydryl Compounds; Tyrosine | 1997 |
Endothelial nitric oxide synthase-dependent superoxide generation from adriamycin.
Topics: Doxorubicin; Electron Spin Resonance Spectroscopy; Endothelium, Vascular; Flavoproteins; Isoenzymes; Models, Chemical; NADP; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Oxidation-Reduction; Superoxides | 1997 |
Poly(ADP-ribose) polymerase gene disruption renders mice resistant to cerebral ischemia.
Topics: Adenosine Triphosphate; Animals; Benzamides; Brain; Cells, Cultured; Cerebral Cortex; Cerebrovascular Circulation; DNA Damage; Enzyme Activation; Enzyme Inhibitors; Hemodynamics; Immunity, Innate; Ischemic Attack, Transient; Isoquinolines; Mice; Mice, Knockout; N-Methylaspartate; NAD; Neurons; Neurotoxins; Nitrates; Nitric Oxide; Piperidines; Poly(ADP-ribose) Polymerases | 1997 |
Activation of NF-kappaB protects hippocampal neurons against oxidative stress-induced apoptosis: evidence for induction of manganese superoxide dismutase and suppression of peroxynitrite production and protein tyrosine nitration.
Topics: Animals; Apoptosis; Cells, Cultured; DNA; Enzyme Activation; Enzyme Inhibitors; Free Radical Scavengers; Hippocampus; Lipid Peroxidation; Neurons; NF-kappa B; Nitrates; Nitrogen Compounds; Oxidants; Oxidative Stress; Rats; Rats, Sprague-Dawley; Sphingosine; Superoxide Dismutase; Tumor Necrosis Factor-alpha; Tyrosine; Uric Acid | 1997 |
Endothelial dysfunction coincides with an enhanced nitric oxide synthase expression and superoxide anion production.
Topics: Animals; Anions; Aorta; Blood Pressure; Constriction, Pathologic; Endothelium, Vascular; Heart; In Vitro Techniques; Isoenzymes; Male; Myocardium; Nitrates; Nitric Oxide Synthase; Organ Size; Perfusion; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Superoxides; Vasodilation | 1997 |
Cytotoxicity of peroxynitrite in rat pancreatic acinar AR4-2J cells.
Topics: Animals; Antioxidants; Apoptosis; Azoles; Calcium; DNA Fragmentation; Dose-Response Relationship, Drug; Genes, p53; Glutathione; Isoindoles; Mutation; Necrosis; Nitrates; Organoselenium Compounds; Pancreas; Pancreatic Neoplasms; Rats; Tumor Cells, Cultured | 1997 |
Peroxynitrite reduces myocardial infarct size and preserves coronary endothelium after ischemia and reperfusion in cats.
Topics: Animals; Cardiotonic Agents; Cats; Cell Adhesion; Coronary Vessels; Endothelium, Vascular; Hemodynamics; In Vitro Techniques; Male; Myocardial Infarction; Myocardial Ischemia; Myocardial Reperfusion; Myocardial Reperfusion Injury; Necrosis; Neutrophils; Nitrates; Oxidants; P-Selectin; Rats; Time Factors | 1997 |
Inactivation of dehydratase [4Fe-4S] clusters and disruption of iron homeostasis upon cell exposure to peroxynitrite.
Topics: Biological Transport; Cytoplasm; Enzyme Activation; Homeostasis; Hydro-Lyases; Iron; Iron-Sulfur Proteins; Nitrates | 1997 |
Glutathione peroxidase protects against peroxynitrite-mediated oxidations. A new function for selenoproteins as peroxynitrite reductase.
Topics: Azoles; Benzoates; Benzoic Acid; Glutathione Peroxidase; Humans; Hydroxylation; Isoindoles; Nitrates; Organoselenium Compounds; Oxidation-Reduction; Oxidoreductases; Proteins; Selenoproteins | 1997 |
The reaction of peroxynitrite with tert-butyl hydroperoxide produces singlet molecular oxygen.
Topics: Deuterium Oxide; Nitrates; Oxidants; Oxygen; Peroxides; Reactive Oxygen Species; Singlet Oxygen; Sodium Azide; Spectrophotometry, Infrared; tert-Butylhydroperoxide; Water | 1997 |
Decreased zinc affinity of amyotrophic lateral sclerosis-associated superoxide dismutase mutants leads to enhanced catalysis of tyrosine nitration by peroxynitrite.
Topics: Amyotrophic Lateral Sclerosis; Animals; Binding Sites; Catalysis; Cloning, Molecular; Humans; Kinetics; Liver; Metallothionein; Models, Structural; Mutagenesis, Site-Directed; Mutation; Nitrates; Protein Conformation; Rabbits; Recombinant Proteins; Superoxide Dismutase; Tyrosine; Zinc | 1997 |
Superoxide dismutase catalyzes nitration of tyrosines by peroxynitrite in the rod and head domains of neurofilament-L.
Topics: Amino Acid Sequence; Animals; Humans; Kinetics; Mass Spectrometry; Mice; Neurofilament Proteins; Nitrates; Recombinant Proteins; Superoxide Dismutase; Tyrosine | 1997 |
Penetration of erythrocyte membrane by peroxynitrite: participation of the anion exchange protein.
Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Adult; Anion Exchange Protein 1, Erythrocyte; Anions; Biological Transport; Erythrocyte Membrane; Hemoglobins; Humans; Hydrogen-Ion Concentration; Nitrates; Oxidation-Reduction | 1997 |
Oxidation of 2',7'-dichlorofluorescin by peroxynitrite.
Topics: Cysteine; Fluoresceins; Hydrogen-Ion Concentration; Indicators and Reagents; Kinetics; Nitrates; Nitric Oxide; Oxidation-Reduction; Superoxides; Uric Acid | 1997 |
Role of peroxynitrite and activation of poly (ADP-ribose) synthase in the vascular failure induced by zymosan-activated plasma.
Topics: Animals; Aorta; Aorta, Thoracic; Blotting, Western; Cells, Cultured; DNA Damage; Enzyme Activation; In Vitro Techniques; Muscle Contraction; Muscle, Smooth, Vascular; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Oxidants; Poly(ADP-ribose) Polymerases; Rats; Tyrosine; Zymosan | 1997 |
Peroxynitrite-induced apoptosis in human intestinal epithelial cells is attenuated by mesalamine.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Cell Line; Epithelial Cells; Humans; Intestines; Mesalamine; Nitrates; Nitric Oxide; Sulfasalazine | 1997 |
Differential induction of c-fos, c-jun, and apoptosis in lung epithelial cells exposed to ROS or RNS.
Topics: Animals; Apoptosis; Cell Line; Epithelial Cells; Genes, fos; Genes, jun; Hydrogen Peroxide; Lung; Molsidomine; Nitrates; Nitric Oxide; Penicillamine; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Rats; Reactive Oxygen Species; RNA, Messenger; S-Nitroso-N-Acetylpenicillamine; Spermine; Transcription, Genetic | 1997 |
Antioxidant properties of S-adenosyl-L-methionine: a proposed addition to organ storage fluids.
Topics: Antioxidants; Free Radical Scavengers; Free Radicals; Glutathione; Lipid Peroxidation; Nitrates; Organ Preservation Solutions; Oxidation-Reduction; Reperfusion Injury; S-Adenosylmethionine | 1997 |
Peroxynitrite: a mediator of increased microvascular permeability?
Topics: Animals; Capillary Permeability; Hydrogen Peroxide; Hydrogen-Ion Concentration; Male; Nitrates; Rats; Rats, Wistar; Skin; Sodium Nitrite | 1997 |
2,7-Dihydrodichlorofluorescein diacetate as a fluorescent marker for peroxynitrite formation.
Topics: Animals; Animals, Newborn; Astrocytes; Cell-Free System; Cells, Cultured; Cerebral Cortex; Chromatography, High Pressure Liquid; Fluoresceins; Fluorescent Dyes; Kinetics; Microscopy, Confocal; Neuroglia; Nitrates; Oxidants; Oxidation-Reduction; Rats; Rats, Wistar; Reactive Oxygen Species; Sensitivity and Specificity | 1997 |
Formation of the NO donors glyceryl mononitrate and glyceryl mononitrite from the reaction of peroxynitrite with glycerol.
Topics: Animals; Aorta; Glycerol; Nitrates; Nitric Oxide; Nitrites; Nitroglycerin; Oxidants; Rabbits; Vasodilator Agents | 1997 |
pH-dependent changes of nitric oxide, peroxynitrite, and reactive oxygen species in hepatocellular damage.
Topics: Animals; Cells, Cultured; Escherichia coli; Gram-Positive Bacterial Infections; Hydrogen-Ion Concentration; Hydroxyl Radical; Lipopolysaccharides; Liver; Male; Nitrates; Nitric Oxide; omega-N-Methylarginine; Propionibacterium acnes; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species | 1997 |
Inhibition of surfactant function by copper-zinc superoxide dismutase (CuZn-SOD).
Topics: Animals; Cattle; Humans; Nitrates; Oxidants; Proteolipids; Pulmonary Surfactant-Associated Proteins; Pulmonary Surfactants; Serum Albumin; Superoxide Dismutase; Surface Properties; Surface Tension | 1997 |
Peroxynitrite-mediated oxidation of D,L-selenomethionine: kinetics, mechanism and the role of carbon dioxide.
Topics: Carbon Dioxide; Ethylenes; Hydrogen-Ion Concentration; Kinetics; Nitrates; Organoselenium Compounds; Oxidants; Oxidation-Reduction; Selenomethionine; Temperature | 1997 |
Amphiphilic peroxynitrite decomposition catalysts in liposomal assemblies.
Topics: Catalysis; Drug Design; Free Radical Scavengers; Liposomes; Manganese; Metalloporphyrins; Models, Chemical; Models, Molecular; Nitrates; Oxidants; Porphyrins | 1997 |
3-Nitrotyrosine in human serum albumin and low density lipoproteins.
Topics: Humans; Lipoproteins, LDL; Nitrates; Oxidants; Serum Albumin; Tyrosine | 1997 |
Nitration of platelet cytosolic proteins by peroxynitrite.
Topics: Blood Platelets; Blood Proteins; Collagen; Cytosol; Humans; In Vitro Techniques; Membrane Proteins; Nitrates; Oxidants; Tyrosine | 1997 |
Production of peroxynitrite from nitric oxide, hydrogen peroxide and superoxide dismutase: pathological implications.
Topics: Hydrogen Peroxide; Kinetics; Nitrates; Nitric Oxide; Oxidants; Superoxide Dismutase | 1997 |
Effect of anti-oxidants on the degradation of SIN-1.
Topics: Antioxidants; Antipyrine; Biotransformation; Cytochrome c Group; Hydrogen Peroxide; Kinetics; Molsidomine; Nitrates; Oxidation-Reduction; Superoxide Dismutase | 1997 |
Protective effect of melatonin in carrageenan-induced models of local inflammation: relationship to its inhibitory effect on nitric oxide production and its peroxynitrite scavenging activity.
Topics: Animals; Antioxidants; Carrageenan; Disease Models, Animal; Dose-Response Relationship, Drug; Edema; Free Radical Scavengers; Immunoenzyme Techniques; Inflammation; Male; Melatonin; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Peroxidase; Pleurisy; Rats; Rats, Sprague-Dawley; Tyrosine | 1997 |
Effect of peroxynitrite on plasma extravasation, microvascular blood flow and nociception in the rat.
Topics: Animals; Capillary Permeability; Catalase; Edema; Male; Nitrates; Pain; Rats; Rats, Wistar; Regional Blood Flow; Skin; Superoxide Dismutase | 1997 |
Thermodynamics of peroxynitrite and its CO2 adduct.
Topics: Carbon Dioxide; Entropy; Free Radicals; Hydroxyl Radical; Nitrates; Nitrogen Dioxide; Oxidants; Oxidation-Reduction; Thermodynamics | 1997 |
Formation and properties of peroxynitrite as studied by laser flash photolysis, high-pressure stopped-flow technique, and pulse radiolysis.
Topics: Buffers; Hydrogen-Ion Concentration; Hydroxyl Radical; Kinetics; Nitrates; Oxidants; Oxidation-Reduction; Photolysis; Pulse Radiolysis | 1997 |
Peroxynitrite protects RAW 264.7 macrophage from Lipopolysaccharide/Interferon-gamma-induced cell death.
Topics: Animals; Cell Death; Cell Line; Cell Survival; Dactinomycin; Dose-Response Relationship, Drug; Glutathione; Interferon-gamma; Lipopolysaccharides; Macrophages; Mice; Nitrates; Nitric Oxide; Nitrogen Oxides; Nitroso Compounds; S-Nitrosoglutathione; Spermine | 1997 |
Peroxynitrite rapidly permeates phospholipid membranes.
Topics: Biological Transport; Cell Membrane Permeability; Lipid Bilayers; Nitrates; Oxidants; Phospholipids | 1997 |
Nitric oxide inactivates NADPH oxidase in pig neutrophils by inhibiting its assembling process.
Topics: Animals; Cytochrome b Group; Electron Spin Resonance Spectroscopy; Flavin-Adenine Dinucleotide; Kinetics; Myristic Acid; NADP; NADPH Oxidases; Neutrophils; Nitrates; Nitric Oxide; Protein Folding; Spectrophotometry, Atomic; Superoxides; Swine | 1997 |
The effects of peroxynitrite on rat aorta: interaction with glucose and related substances.
Topics: Animals; Aorta; Dose-Response Relationship, Drug; Drug Interactions; Endothelium, Vascular; Glucose; Glycerol; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Nitrates; Oxidants; Pharmaceutical Vehicles; Phenylephrine; Rats; Rats, Wistar; Vasoconstrictor Agents | 1997 |
Peroxynitrite modulates tyrosine-dependent signal transduction pathway of human erythrocyte band 3.
Topics: Amino Acid Sequence; Anion Exchange Protein 1, Erythrocyte; Erythrocytes; Glycolysis; Hemoglobins; Humans; In Vitro Techniques; Molecular Sequence Data; Nitrates; Oxidation-Reduction; Phosphorylation; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Signal Transduction; Tyrosine | 1997 |
Peroxynitrite-induced toxicity in cultured astrocytes.
Topics: Animals; Animals, Newborn; Astrocytes; Cell Death; Cells, Cultured; Cerebral Cortex; Enzyme Inhibitors; Glutathione; Hydrogen-Ion Concentration; Kinetics; L-Lactate Dehydrogenase; Molsidomine; Nitrates; Nitric Oxide; Nitroso Compounds; Oxidants; Rats; S-Nitrosoglutathione; Superoxides | 1997 |
Evidence for the production of peroxynitrite in inflammatory CNS demyelination.
Topics: Acute Disease; Animals; Chronic Disease; Encephalomyelitis, Autoimmune, Experimental; Female; Immunohistochemistry; Mice; Mice, Inbred Strains; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Recurrence; Remission Induction; Serum Albumin, Bovine; Spinal Cord; Tyrosine | 1997 |
[Does selenium prevent peroxynitrite formation from NO in vascular surgery interventions? A clinical study].
Topics: Aged; Antioxidants; Arteriosclerosis; Female; Glutathione Peroxidase; Humans; Male; Middle Aged; Nitrates; Nitric Oxide; Reperfusion Injury; Sodium Selenite | 1997 |
Differential modulation of the uptake currents by redox interconversion of cysteine residues in the human neuronal glutamate transporter EAAC1.
Topics: Amino Acid Transport System X-AG; Animals; Carrier Proteins; Cysteine; Dithionitrobenzoic Acid; Dithiothreitol; Evoked Potentials; Excitatory Amino Acid Transporter 3; Female; Glutamate Plasma Membrane Transport Proteins; Glutamates; Humans; Neurons; Nitrates; Oocytes; Oxidants; Oxidation-Reduction; Patch-Clamp Techniques; Symporters; Xenopus | 1997 |
Role of peroxynitrite in the protein oxidation and apoptotic DNA fragmentation in vascular smooth muscle cells stimulated with bacterial lipopolysaccharide and interferon-gamma.
Topics: Animals; Apoptosis; Benzamides; Cells, Cultured; DNA Fragmentation; Enzyme Inhibitors; Interferon-gamma; Lipopolysaccharides; Muscle, Smooth, Vascular; Nitrates; Nitric Oxide; Oxidants; Oxidation-Reduction; Poly(ADP-ribose) Polymerase Inhibitors; Proteins; Rats | 1997 |
Scavenging of hydroxyl radicals but not of peroxynitrite by inhibitors and substrates of nitric oxide synthases.
Topics: alpha 1-Antitrypsin; Dose-Response Relationship, Drug; Enzyme Inhibitors; Free Radical Scavengers; Free Radicals; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide Synthase; Oxidants; Tyrosine | 1997 |
Mitochondrial manganese superoxide dismutase prevents neural apoptosis and reduces ischemic brain injury: suppression of peroxynitrite production, lipid peroxidation, and mitochondrial dysfunction.
Topics: Animals; Apoptosis; Brain Ischemia; Cell Line; Cysteine Endopeptidases; Humans; Intracellular Membranes; Lipid Peroxidation; Membrane Lipids; Mice; Mice, Transgenic; Mitochondria; Neurons; Nitrates; Nitric Oxide; Oxidative Stress; Superoxide Dismutase; Tyrosine | 1998 |
One-electron oxidation pathway of thiols by peroxynitrite in biological fluids: bicarbonate and ascorbate promote the formation of albumin disulphide dimers in human blood plasma.
Topics: Ascorbic Acid; Blood Proteins; Chromatography, Gel; Chromatography, High Pressure Liquid; Dimerization; Electron Spin Resonance Spectroscopy; Electrons; Free Radicals; Humans; Nitrates; Oxidation-Reduction; Serum Albumin; Sodium Bicarbonate; Sulfhydryl Compounds | 1998 |
Lipopolysaccharide-induced increase in plasma nitrotyrosine concentrations in rats.
Topics: 4-Chloro-7-nitrobenzofurazan; Animals; Lipopolysaccharides; Male; Nitrates; Nitrites; Rats; Rats, Wistar; Tyrosine | 1997 |
Uric acid, a natural scavenger of peroxynitrite, in experimental allergic encephalomyelitis and multiple sclerosis.
Topics: Animals; Encephalomyelitis, Autoimmune, Experimental; Female; Humans; Mice; Mice, Knockout; Multiple Sclerosis; Nitrates; Uric Acid | 1998 |
Nitric oxide and superoxide contribute to motor neuron apoptosis induced by trophic factor deprivation.
Topics: Animals; Apoptosis; Brain-Derived Neurotrophic Factor; Cells, Cultured; Enzyme Inhibitors; Fetus; Free Radical Scavengers; Motor Neurons; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Oxidants; Rats; Spinal Cord; Superoxides; Tyrosine | 1998 |
Reactions of peroxynitrite with aldehydes as probes for the reactive intermediates responsible for biological nitration.
Topics: Acetaldehyde; Aldehydes; Animals; Cattle; Free Radical Scavengers; Nitrates; Oxidants; Rabbits | 1997 |
Ternary copper complexes and manganese (III) tetrakis(4-benzoic acid) porphyrin catalyze peroxynitrite-dependent nitration of aromatics.
Topics: Chelating Agents; Copper; Free Radical Scavengers; Hydrogen-Ion Concentration; Kinetics; Metalloporphyrins; Nitrates; Oxidants; Phenanthrolines; Phenylacetates; Spectrophotometry, Ultraviolet; Structure-Activity Relationship | 1997 |
Antiinflammatory effects of mercaptoethylguanidine, a combined inhibitor of nitric oxide synthase and peroxynitrite scavenger, in carrageenan-induced models of inflammation.
Topics: Animals; Carrageenan; Disease Models, Animal; Edema; Enzyme Inhibitors; Free Radical Scavengers; Guanidines; Inflammation; Lung; Male; Neutrophils; Nitrates; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; Oxidants; Pleurisy; Rats; Rats, Sprague-Dawley | 1998 |
Inactivation of glutathione peroxidase by peroxynitrite.
Topics: Animals; Cattle; Enzyme Activation; Glutathione Peroxidase; Kinetics; Nitrates; Oxidants | 1998 |
Formation of spin trap adducts during the decomposition of peroxynitrite.
Topics: Free Radicals; Nitrates; Spin Trapping | 1998 |
Peroxynitrite-mediated heme oxidation and protein modification of native and chemically modified hemoglobins.
Topics: Heme; Hemoglobins; Humans; Nitrates; Oxidants; Oxidation-Reduction | 1998 |
Role of tryptophan oxidation in peroxynitrite-dependent protein chemiluminescence.
Topics: Animals; Cattle; Luminescent Measurements; Nitrates; Oxidation-Reduction; Serum Albumin, Bovine; Tryptophan | 1998 |
The mechanism of the peroxynitrite-carbon dioxide reaction probed using tyrosine.
Topics: Carbon Dioxide; Kinetics; Molecular Probes; Nitrates | 1997 |
Nitric oxide and peroxynitrite affect differently acetylcholine release, choline acetyltransferase activity, synthesis, and compartmentation of newly formed acetylcholine in Torpedo marmorata synaptosomes.
Topics: Acetylcholine; Animals; Calcimycin; Cell Compartmentation; Choline O-Acetyltransferase; Electric Organ; Enzyme Inhibitors; Molsidomine; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Potassium Chloride; Synaptosomes; Torpedo | 1997 |
Indirect oxidation of ferrocyanide by peroxynitrite--evidence against the formation of hydroxyl radicals.
Topics: Air; Argon; Ferrocyanides; Hydrogen-Ion Concentration; Hydroxyl Radical; Kinetics; Models, Chemical; Nitrates; Oxidants; Oxidation-Reduction | 1997 |
In situ measurement of nitric oxide, superoxide and peroxynitrite during endotoxemia.
Topics: Animals; Aorta; Endothelium, Vascular; Endotoxemia; Escherichia coli; Lipopolysaccharides; Nitrates; Nitric Oxide; Rats; Rats, Inbred WKY; Superoxides | 1997 |
Alpha-tocopherol in rat brain subcellular fractions is oxidized rapidly during incubations with low concentrations of peroxynitrite.
Topics: Animals; Antioxidants; Brain; Cells, Cultured; Dose-Response Relationship, Drug; Male; Nitrates; Oxidants; Oxidation-Reduction; Rats; Rats, Inbred F344; Synaptosomes; Vitamin E | 1998 |
Peroxynitrite and hydrogen peroxide induced cell death in the NSC34 neuroblastoma x spinal cord cell line: role of poly (ADP-ribose) polymerase.
Topics: Animals; Benzamides; Cell Death; Cell Survival; Dactinomycin; DNA Damage; Enzyme Inhibitors; Hybrid Cells; Hydrogen Peroxide; Kinetics; Neuroblastoma; Niacinamide; Nitrates; Oxidants; Phenanthrenes; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Spinal Cord | 1998 |
Angiotensin II stimulates the production of NO and peroxynitrite in endothelial cells.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Aorta, Thoracic; Arginine; Bradykinin; Calcium; Calmodulin; Cells, Cultured; Endothelium, Vascular; Losartan; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Oxidants; Rats; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Sulfonamides | 1998 |
Nitric oxide and peroxynitrite-mediated pulmonary cell death.
Topics: Acetylcysteine; Animals; Cattle; Cell Death; Cells, Cultured; Endothelium, Vascular; Epithelial Cells; Kinetics; Lung; Male; Molsidomine; Nitrates; Nitric Oxide; Nitrogen Oxides; Oxidants; Pulmonary Artery; Rats; Rats, Sprague-Dawley; Spermine | 1998 |
The effects of nitric oxide and peroxynitrite on interleukin-8 and elastase from lipopolysaccharide-stimulated whole blood.
Topics: Free Radical Scavengers; Humans; In Vitro Techniques; Interleukin-8; Leukocyte Elastase; Lipopolysaccharides; Male; Molsidomine; Nitrates; Nitric Oxide; Triazoles | 1998 |
Expression of iNOS, eNOS, and peroxynitrite-modified proteins in experimental anti-myeloperoxidase associated crescentic glomerulonephritis.
Topics: Animals; Anti-Glomerular Basement Membrane Disease; Cell Extracts; Disease Models, Animal; Hydrogen Peroxide; Lysosomes; Necrosis; Nitrates; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Oxidants; Peroxidase; Proteinuria; Rats; Superoxides | 1998 |
Cysteine oxidation in the mitogenic S100B protein leads to changes in phosphorylation by catalytic CKII-alpha subunit.
Topics: Amino Acid Sequence; Animals; Binding Sites; Calcium-Binding Proteins; Casein Kinase II; Cattle; Cell Division; Cysteine; Dimerization; Disulfides; Mitogens; Molecular Sequence Data; Nerve Growth Factors; Neuroglia; Nitrates; Oxidation-Reduction; Phosphorylation; Protein Conformation; Protein Serine-Threonine Kinases; Rats; S100 Calcium Binding Protein beta Subunit; S100 Proteins; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Thymidine | 1998 |
Peroxynitrite aggravates myocardial reperfusion injury in the isolated perfused rat heart.
Topics: Animals; Creatine Kinase; Glutathione; L-Lactate Dehydrogenase; Male; Molsidomine; Myocardial Contraction; Myocardial Reperfusion Injury; Myocardium; Nitrates; Perfusion; Rats; Rats, Sprague-Dawley; Superoxide Dismutase; Vasodilator Agents | 1997 |
Thiols protect the inhibition of myocardial aconitase by peroxynitrite.
Topics: Aconitate Hydratase; Animals; Citrates; Cysteine; Dose-Response Relationship, Drug; Drug Interactions; Ferrous Compounds; Glutathione; Glycine; Male; Myocardium; Nitrates; Penicillamine; Quaternary Ammonium Compounds; Rats; Rats, Sprague-Dawley; S-Nitroso-N-Acetylpenicillamine; Sulfhydryl Compounds | 1998 |
Oxidation, nitrosation, and nitration of serotonin by nitric oxide-derived nitrogen oxides: biological implications in the rat vascular system.
Topics: Animals; Blood Pressure; Cell Line; Dimerization; Free Radicals; Gamma Rays; Heart Rate; Hemodynamics; Hydrogen-Ion Concentration; Kinetics; Molecular Structure; Nitrates; Nitric Oxide; Nitro Compounds; Nitrogen Oxides; Nitroso Compounds; Nitrous Acid; Oxygen; Rats; Receptors, Serotonin; Serotonin; Transfection | 1997 |
Peroxynitrite-induced apoptosis in epithelial (T84) and macrophage (RAW 264.7) cell lines: effect of legume-derived polyphenols (phytolens).
Topics: Animals; Antioxidants; Apoptosis; Bepridil; Biphenyl Compounds; Cell Division; Cell Line; Cell Survival; Colonic Neoplasms; DNA Fragmentation; Fabaceae; Flavonoids; Free Radical Scavengers; Humans; Inflammation; Macrophages; Nitrates; Phenols; Picrates; Plants, Medicinal; Polymers; Polyphenols; Rats; Superoxides | 1997 |
Catalysis of peroxynitrite reactions by manganese and iron porphyrins.
Topics: Alcohol Dehydrogenase; Catalysis; Free Radicals; Iron; Kinetics; Manganese; Molecular Structure; Nitrates; Oxygen; Phenols; Porphyrins; Sulfoxides; Thiophenes | 1997 |
Nitrosating agents: is peroxynitrite a likely candidate?
Topics: Copper; Free Radicals; Nitrates; Nitric Oxide; Nitrosation; Nitroso Compounds; Nitrous Acid; Peroxynitrous Acid; Silver; Sulfhydryl Compounds | 1997 |
Peroxynitrite formation in focal cerebral ischemia-reperfusion in rats occurs predominantly in the peri-infarct region.
Topics: Animals; Chromatography, High Pressure Liquid; Ischemic Attack, Transient; Male; Nitrates; Rats; Rats, Sprague-Dawley; Reperfusion; Tyrosine | 1998 |
Neuroprotection by S-nitrosoglutathione of brain dopamine neurons from oxidative stress.
Topics: Animals; Autoradiography; Citric Acid; Cocaine; Dopamine; Ferrous Compounds; Glutathione; Infusions, Parenteral; Iodine Radioisotopes; Lipid Peroxidation; Male; Neurons; Neuroprotective Agents; Nitrates; Nitroso Compounds; Oxidants; Oxidative Stress; Rats; Rats, Sprague-Dawley; S-Nitrosoglutathione; Substantia Nigra | 1998 |
Augmentation of nitric oxide, superoxide, and peroxynitrite production during cerebral ischemia and reperfusion in the rat.
Topics: Animals; Brain Ischemia; Enzyme Induction; Immunohistochemistry; Leukocyte Count; Male; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; Rats; Rats, Wistar; Reperfusion; Superoxides | 1998 |
Intracellular but not extracellular conversion of nitroxyl anion into nitric oxide leads to stimulation of human neutrophil migration.
Topics: Chemotaxis, Leukocyte; Cyclic GMP; Free Radicals; Humans; In Vitro Techniques; Methionine; Neutrophils; Nitrates; Nitric Oxide; Nitrites; Nitrogen Oxides; Oxidants | 1998 |
Peroxynitrite decomposition catalysts: therapeutics for peroxynitrite-mediated pathology.
Topics: Animals; Carrageenan; Catalysis; Cell Death; Cell Line; Edema; L-Lactate Dehydrogenase; Macrophages; Male; Models, Chemical; Nitrates; Nitrites; Oxidants; Porphyrins; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship | 1998 |
Peroxynitrite-mediated inactivation of manganese superoxide dismutase involves nitration and oxidation of critical tyrosine residues.
Topics: Crystallography, X-Ray; Cysteine; Enzyme Activation; Humans; Immunoblotting; Manganese; Models, Molecular; Nitrates; Oxidation-Reduction; Protein Binding; Superoxide Dismutase; Tyrosine | 1998 |
Markers of protein oxidation by hydroxyl radical and reactive nitrogen species in tissues of aging rats.
Topics: Aging; Animals; Antioxidants; Biomarkers; Copper; Female; Free Radicals; Gas Chromatography-Mass Spectrometry; Hydrogen Peroxide; Hydroxyl Radical; Nitrates; Nitrogen; Oxidation-Reduction; Oxidative Stress; Proteins; Rats; Serum Albumin, Bovine; Tyrosine | 1998 |
Vascular function in the vitamin E-deprived rat: an interaction between nitric oxide and superoxide anions.
Topics: Animals; Blotting, Western; Dose-Response Relationship, Drug; Endothelium, Vascular; Female; Mesenteric Arteries; Nitrates; Nitric Oxide; Oxidants; Phenylephrine; Rats; Rats, Sprague-Dawley; Superoxide Dismutase; Superoxides; Vasoconstrictor Agents; Vasodilation; Vitamin E Deficiency | 1998 |
Inhibition of nitric oxide synthase attenuates peroxynitrite generation, but augments neutrophil accumulation in hepatic ischemia-reperfusion in rats.
Topics: Alanine Transaminase; Animals; Enzyme Inhibitors; Intercellular Adhesion Molecule-1; Ischemia; Liver; Male; Neutrophils; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Polymerase Chain Reaction; Rats; Rats, Inbred F344; Reperfusion Injury; Superoxides | 1998 |
Poly(ADP-ribose) synthetase activation mediates increased permeability induced by peroxynitrite in Caco-2BBe cells.
Topics: Adenosine Triphosphate; Caco-2 Cells; DNA Damage; Humans; Inflammatory Bowel Diseases; Intestinal Mucosa; Molsidomine; Nitrates; Nitric Oxide; Penicillamine; Permeability; Poly(ADP-ribose) Polymerases; S-Nitroso-N-Acetylpenicillamine | 1998 |
Nitric oxide and intestinal epithelia: just say NO.
Topics: Humans; Intestinal Mucosa; NAD; Nitrates; Nitric Oxide; Poly(ADP-ribose) Polymerases | 1998 |
Nitric oxide superoxide and peroxynitrite modulate osteoclast activity.
Topics: Animals; Animals, Newborn; Bone Resorption; Calcium; Catalase; Cells, Cultured; Cyclic GMP; Enzyme Activation; Hydrogen Peroxide; Molsidomine; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Osteoclasts; Rats; Rats, Sprague-Dawley; Superoxides; Thionucleotides | 1998 |
Carbon dioxide stimulates peroxynitrite-mediated nitration of tyrosine residues and inhibits oxidation of methionine residues of glutamine synthetase: both modifications mimic effects of adenylylation.
Topics: Adenosine Monophosphate; Carbon Dioxide; Escherichia coli; Gene Expression Regulation, Enzymologic; Glutamate-Ammonia Ligase; Methionine; Models, Chemical; Models, Molecular; Nitrates; Oxidation-Reduction; Tyrosine | 1998 |
Effect of L-buthionine-(S,R)-sulphoximine, an inhibitor of gamma-glutamylcysteine synthetase on peroxynitrite- and endotoxic shock-induced vascular failure.
Topics: Animals; Aorta, Thoracic; Buthionine Sulfoximine; Cell Survival; Cells, Cultured; Endothelium, Vascular; Enzyme Induction; Enzyme Inhibitors; Glutamate-Cysteine Ligase; Glutathione; Humans; In Vitro Techniques; Muscle Contraction; Nitrates; Nitric Oxide Synthase; Rats; Shock, Septic | 1998 |
Can O=NOOH undergo homolysis?
Topics: Entropy; Hydroxyl Radical; Nitrates; Nitrogen Dioxide; Protons; Thermodynamics | 1998 |
Sulphite enhances peroxynitrite-dependent alpha1-antiproteinase inactivation. A mechanism of lung injury by sulphur dioxide?
Topics: Asthma; Copper; Dose-Response Relationship, Drug; Enzyme Repression; Humans; Intracellular Signaling Peptides and Proteins; Iron; Lung; Nitrates; Proteins; Sulfites; Sulfur Dioxide | 1998 |
Interaction of peroxynitrite with carotenoids and tocopherols within low density lipoprotein.
Topics: beta Carotene; Carotenoids; Copper; Lipid Peroxidation; Lipoproteins, LDL; Lycopene; Molecular Structure; Nitrates; Oxidation-Reduction; Quinones; Vitamin E | 1998 |
Diffusion of peroxynitrite across erythrocyte membranes.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Biological Transport; Erythrocyte Membrane; Humans; Hydrogen-Ion Concentration; Nitrates; Oxidants; Oxidation-Reduction | 1998 |
Protection against peroxynitrite-induced fibroblast injury and arthritis development by inhibition of poly(ADP-ribose) synthase.
Topics: Animals; Arthritis; Coumarins; DNA Damage; Enzyme Inhibitors; Fibroblasts; Mice; Nitrates; Oxidants; Poly(ADP-ribose) Polymerase Inhibitors | 1998 |
Endotoxin-induced skeletal muscle contractile dysfunction: contribution of nitric oxide synthases.
Topics: Animals; Disease Models, Animal; Lipopolysaccharides; Male; Muscle Contraction; Muscle, Skeletal; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Rats; Rats, Sprague-Dawley; Shock, Septic | 1998 |
Direct measurement of nitric oxide release in gastric mucosa during ischemia-reperfusion in rats.
Topics: Animals; Electrodes; Enzyme Inhibitors; Gastric Mucosa; Ischemia; Male; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Penicillamine; Rats; Rats, Wistar; Regional Blood Flow; Reperfusion; S-Nitroso-N-Acetylpenicillamine; Stomach; Superoxide Dismutase; Superoxides | 1998 |
Peroxynitrite-mediated vasorelaxation: evidence against the formation of circulating S-nitrosothiols.
Topics: Animals; Blood Flow Velocity; Cysteine; Glutathione; Hemodynamics; Male; Mercaptoethanol; Nitrates; Nitroso Compounds; Penicillamine; Rats; Rats, Sprague-Dawley; Regional Blood Flow; S-Nitrosoglutathione; S-Nitrosothiols; Serum Albumin, Bovine; Vasodilation | 1998 |
Peroxynitrite modulates tyrosine phosphorylation and phosphoinositide signalling in human neuroblastoma SH-SY5Y cells: attenuated effects in human 1321N1 astrocytoma cells.
Topics: Astrocytoma; Cell Membrane; Cytosol; Humans; Hydrolysis; Ionomycin; Neuroblastoma; Nitrates; Phosphatidylinositols; Phosphoproteins; Phosphorylation; Phosphotyrosine; Signal Transduction; Sodium Fluoride; Tumor Cells, Cultured | 1998 |
Peroxynitrite-mediated DNA strand breakage activates poly (ADP-ribose) synthetase and causes cellular energy depletion in carrageenan-induced pleurisy.
Topics: Animals; Blotting, Western; Carrageenan; Cell Culture Techniques; DNA Damage; Energy Metabolism; Macrophages; Male; Nitrates; Pleura; Pleurisy; Poly(ADP-ribose) Polymerases; Rats; Rats, Sprague-Dawley | 1998 |
Increased expression of an inducible isoform of nitric oxide synthase and the formation of peroxynitrite in colonic mucosa of patients with active ulcerative colitis.
Topics: Acute Disease; Adolescent; Adult; Analysis of Variance; Antibodies, Monoclonal; Blotting, Western; Colitis, Ulcerative; Colon; Enzyme Induction; Female; Humans; Immunohistochemistry; Intestinal Mucosa; Isoenzymes; Male; Middle Aged; Nitrates; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Tyrosine | 1998 |
Molecular actions of a Mn(III)Porphyrin superoxide dismutase mimetic and peroxynitrite scavenger: reaction with nitric oxide and direct inhibition of NO synthase and soluble guanylyl cyclase.
Topics: Animals; Cells, Cultured; Endothelium, Vascular; Free Radical Scavengers; Glutathione; Guanylate Cyclase; Humans; Manganese; Metalloporphyrins; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Rats; Solubility; Spectrophotometry; Superoxide Dismutase; Swine | 1998 |
Free radical formation in the peroxynitrous acid (ONOOH)/peroxynitrite (ONOO-) system.
Topics: Free Radicals; Nitrates; Nitrous Acid; Oxidants; Peroxynitrous Acid | 1998 |
Peroxynitrite increases the degradation of aconitase and other cellular proteins by proteasome.
Topics: Aconitate Hydratase; Cysteine Endopeptidases; Enzyme Inhibitors; Humans; Hydrogen Peroxide; Hydrolysis; Molsidomine; Multienzyme Complexes; Nitrates; Oxidative Stress; Proteasome Endopeptidase Complex; Tumor Cells, Cultured | 1998 |
The critical role of Hepes in SIN-1 cytotoxicity, peroxynitrite versus hydrogen peroxide.
Topics: Animals; Buffers; Catalase; Cell Death; Cell Line; Fibroblasts; HEPES; Hydrogen Peroxide; Kinetics; L-Lactate Dehydrogenase; Mice; Molsidomine; Nitrates | 1998 |
Inhibition of peroxynitrite dependent tyrosine nitration by hydroxycinnamates: nitration or electron donation?
Topics: Antioxidants; Caffeic Acids; Chlorogenic Acid; Chromans; Chromatography, High Pressure Liquid; Coumaric Acids; Free Radical Scavengers; Free Radicals; Nitrates; Spectrophotometry; Tyrosine | 1998 |
Determination of optimal conditions for synthesis of peroxynitrite by mixing acidified hydrogen peroxide with nitrite.
Topics: Cold Temperature; Hydrogen Peroxide; Hydrogen-Ion Concentration; Kinetics; Nitrates; Nitrites; Osmolar Concentration; Oxidants; Perchlorates; Solutions; Thermodynamics | 1998 |
Control of growth and differentiation of normal human epithelial cells through the manipulation of reactive nitrogen species.
Topics: Catalase; Cell Differentiation; Cell Division; Cyclic N-Oxides; Fluorescent Antibody Technique; Free Radical Scavengers; Humans; Hydrazines; Imidazoles; Keratinocytes; Molsidomine; Nitrates; Nitric Oxide; Superoxide Dismutase; Thymidine | 1998 |
Plasma 3-nitrotyrosine is elevated in premature infants who develop bronchopulmonary dysplasia.
Topics: Bronchopulmonary Dysplasia; Female; Humans; Infant, Newborn; Infant, Premature; Male; Nitrates; Oxidants; Oxidative Stress; Pilot Projects; Retrospective Studies; Tyrosine | 1998 |
Catalase catalyzes of peroxynitrite-mediated phenolic nitration.
Topics: Animals; Catalase; Catalysis; Cattle; Escherichia coli; Hydrogen-Ion Concentration; Kinetics; Microbial Sensitivity Tests; Nitrates; Oxidants; Phenylacetates; Superoxide Dismutase | 1998 |
Peroxynitrite and brain mitochondria: evidence for increased proton leak.
Topics: Animals; Brain; Male; Membrane Potentials; Mitochondria; Nitrates; Oxidants; Oxygen Consumption; Permeability; Protons; Rats; Rats, Wistar | 1998 |
Peroxynitrite induces apoptosis of HL-60 cells by activation of a caspase-3 family protease.
Topics: Apoptosis; Caspase 3; Caspases; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Enzyme Activation; HL-60 Cells; Humans; Nitrates; Oxidants; Peptide Hydrolases; Poly(ADP-ribose) Polymerases | 1998 |
Inhibition of rat cardiac muscle contraction and mitochondrial respiration by endogenous peroxynitrite formation during posthypoxic reoxygenation.
Topics: Animals; Bradykinin; Cyclic GMP; Free Radical Scavengers; Hydroxyl Radical; Hypoxia; In Vitro Techniques; Kinetics; Mannitol; Mitochondria, Heart; Myocardial Contraction; Nitrates; Nitric Oxide; Nitroarginine; Oxidants; Oxygen Consumption; Penicillamine; Rats; S-Nitroso-N-Acetylpenicillamine; Sodium Cyanide; Superoxide Dismutase | 1998 |
Reactions of nitric oxide with mitochondrial cytochrome c: a novel mechanism for the formation of nitroxyl anion and peroxynitrite.
Topics: Cytochrome c Group; Electron Spin Resonance Spectroscopy; Fungal Proteins; Kinetics; Metmyoglobin; Mitochondria; Myocardium; Nitrates; Nitric Oxide; Nitrogen Oxides; Oxygen; Protein Binding; Spectrophotometry | 1998 |
Chemical modifications of the vasoconstrictor peptide angiotensin II by nitrogen oxides (NO, HNO2, HOONO)--evaluation by mass spectrometry.
Topics: Angiotensin II; Animals; Arginine; Humans; Magnetic Resonance Spectroscopy; Mass Spectrometry; Molecular Structure; Molecular Weight; Nitrates; Nitrogen Oxides; Oxidants; Rats; Rats, Sprague-Dawley; Vasoconstriction; Vasoconstrictor Agents | 1998 |
[Effect of carbon dioxide on peroxynitrite reaction with DNA].
Topics: Animals; Carbon Dioxide; Cattle; DNA; Dose-Response Relationship, Drug; Guanine; Nitrates; Thymus Gland | 1998 |
Hydrogen peroxide formation by reaction of peroxynitrite with HEPES and related tertiary amines. Implications for a general mechanism.
Topics: Amines; Animals; Bicarbonates; Carbon Dioxide; Cattle; HEPES; Hydrogen Peroxide; Molsidomine; Nitrates; Oxygen; Superoxide Dismutase; Tryptophan | 1998 |
Mutations induced in the supF gene of pSP189 by hydroxyl radical and singlet oxygen: relevance to peroxynitrite mutagenesis.
Topics: Amino Acid Sequence; Base Sequence; Escherichia coli; Genes, Bacterial; Humans; Hydroxyl Radical; Molecular Sequence Data; Mutagens; Mutation; Nitrates; Plasmids; Reactive Oxygen Species; Transfection; Transformation, Bacterial | 1998 |
Reaction of peroxynitrite with HEPES or MOPS results in the formation of nitric oxide donors.
Topics: Animals; Buffers; Cells, Cultured; Endothelium, Vascular; HEPES; Nitrates; Nitric Oxide; Oxidants; Swine | 1998 |
Protection by organotellurium compounds against peroxynitrite-mediated oxidation and nitration reactions.
Topics: Antioxidants; Benzoates; Benzoic Acid; Cells, Cultured; Fibroblasts; Glutathione Peroxidase; Humans; Hydroxylation; Nitrates; Organometallic Compounds; Oxidants; Oxidation-Reduction; Phenylacetates; Rhodamines; Tellurium | 1998 |
Bilirubin is an effective antioxidant of peroxynitrite-mediated protein oxidation in human blood plasma.
Topics: Antioxidants; Bilirubin; Blood Proteins; Carbon Dioxide; Fluorescence; Humans; Hydrogen-Ion Concentration; Nitrates; Oxidation-Reduction; Peroxides; Sodium Bicarbonate; Spectrophotometry; Tryptophan; Tyrosine | 1998 |
Role of nitric oxide and peroxynitrite in the cytokine-induced sustained myocardial dysfunction in dogs in vivo.
Topics: Animals; Creatine Kinase; Cytokines; Dexamethasone; Disease Models, Animal; Dogs; Guanidines; Heart; Hemodynamics; Histocytochemistry; Inflammation; Interleukin-1; Isoenzymes; Leukocyte Count; Microspheres; Myocardium; Nitrates; Nitric Oxide; Peroxidase; Tyrosine; Ventricular Dysfunction, Left | 1998 |
Scavenging of peroxynitrite by a phenolic/peroxidase system prevents oxidative damage to DNA.
Topics: Chlorogenic Acid; DNA; DNA Damage; Free Radical Scavengers; Horseradish Peroxidase; Kinetics; Nitrates; Oxidation-Reduction; Plasmids | 1998 |
Interaction between peroxynitrite and L-cysteine: effects on rat aorta.
Topics: Animals; Aorta; Cysteine; Drug Interactions; In Vitro Techniques; Male; Muscle, Smooth, Vascular; Nitrates; Oxidants; Rats; Rats, Wistar | 1998 |
(-)-Deprenyl protects human dopaminergic neuroblastoma SH-SY5Y cells from apoptosis induced by peroxynitrite and nitric oxide.
Topics: Antiparkinson Agents; Apoptosis; DNA Damage; Dopamine; Electrophoresis, Agar Gel; Humans; Molsidomine; Monoamine Oxidase Inhibitors; Neuroblastoma; Nitrates; Nitric Oxide; Oxidants; Pyridines; Selegiline; Tumor Cells, Cultured | 1998 |
Nitric oxide production and perivascular tyrosine nitration following focal ischemia in neonatal rat.
Topics: Animals; Animals, Newborn; Brain; Cell Death; Female; Immunoenzyme Techniques; Ischemic Attack, Transient; Male; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Oxidants; Rats; Rats, Wistar; Reperfusion Injury; Tyrosine | 1998 |
Role of peroxynitrite and poly (ADP-ribose) synthetase on cellular energy depletion in carrageenan-induced pleurisy.
Topics: Animals; Benzamides; Carrageenan; Cell Respiration; Cells, Cultured; DNA Damage; DNA, Single-Stranded; Enzyme Activation; Enzyme Inhibitors; Macrophages; Male; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide Synthase; Pleura; Pleurisy; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Rats; Rats, Sprague-Dawley | 1998 |
Helicobacter pylori generates superoxide radicals and modulates nitric oxide metabolism.
Topics: Escherichia coli; Helicobacter pylori; Kinetics; Nitrates; Nitric Oxide; Oxygen Consumption; Superoxide Dismutase; Superoxides | 1998 |
Inactivation of human manganese-superoxide dismutase by peroxynitrite is caused by exclusive nitration of tyrosine 34 to 3-nitrotyrosine.
Topics: Amino Acid Sequence; Enzyme Inhibitors; Humans; Mass Spectrometry; Mitochondria; Molecular Sequence Data; Nitrates; Peptide Fragments; Recombinant Proteins; Sequence Analysis; Serine Endopeptidases; Superoxide Dismutase; Tyrosine | 1998 |
Rapid and irreversible inhibition of creatine kinase by peroxynitrite.
Topics: Acetonitriles; Animals; Creatine Kinase; Enzyme Activation; Enzyme Inhibitors; Enzyme Reactivators; Glutathione; Glutathione Disulfide; Kinetics; Molsidomine; Morpholines; Nitrates; Nitric Oxide; Oxidants; Rabbits; Sulfhydryl Compounds; Superoxides | 1998 |
Peroxynitrite inhibits amiloride-sensitive Na+ currents in Xenopus oocytes expressing alpha beta gamma-rENaC.
Topics: Amiloride; Animals; Calcium; Electric Conductivity; Epithelial Sodium Channels; Female; Molsidomine; Nitrates; Oocytes; Oxidants; Rats; Sodium; Sodium Channels; Tetranitromethane; Xenopus laevis | 1998 |
Peroxynitrate-mediated DNA strand breakage activates poly(ADP-ribose) synthetase and causes cellular energy depletion in a nonseptic shock model induced by zymosan in the rat.
Topics: Animals; Benzamides; Disease Models, Animal; DNA Damage; Energy Metabolism; Enzyme Activation; Macrophages, Peritoneal; Male; Mitochondria; NAD; NG-Nitroarginine Methyl Ester; Niacinamide; Nitrates; Nitric Oxide Synthase; Oxidants; Oxygen Consumption; Poly(ADP-ribose) Polymerases; Rats; Rats, Sprague-Dawley; Shock; Zymosan | 1998 |
Potential role of the peroxynitrate-poly(ADP-ribose) synthetase pathway in a rat model of severe hemorrhagic shock.
Topics: Animals; Blood Pressure; Cell Nucleus; Death; Disease Models, Animal; DNA Damage; Male; Models, Biological; Nitrates; Oxidants; Poly(ADP-ribose) Polymerases; Rats; Rats, Wistar; Resuscitation; Shock, Hemorrhagic | 1998 |
Functional implications of nitric oxide produced by mitochondria in mitochondrial metabolism.
Topics: Adenosine Triphosphate; Animals; Cell Respiration; Electron Transport Complex IV; Free Radicals; Gases; In Vitro Techniques; Mitochondria, Liver; Nitrates; Nitric Oxide; Oxidation-Reduction; Oxygen Consumption; Phosphorylation; Rats | 1998 |
Characterization of the cytoprotective action of peroxynitrite decomposition catalysts.
Topics: Animals; Catalysis; Cell Death; Ferric Compounds; Humans; Inflammation; Metalloporphyrins; Nitrates; Nitric Oxide; Porphyrins; Rats; Tumor Cells, Cultured | 1998 |
Nitrotyrosine-protein adducts in hepatic centrilobular areas following toxic doses of acetaminophen in mice.
Topics: Acetaminophen; Alanine Transaminase; Analgesics, Non-Narcotic; Animals; Biotransformation; Liver; Male; Mice; Nitrates; Nitric Oxide; Proteins; Tyrosine | 1998 |
Slowing of peroxynitrite decomposition in the presence of mannitol and ethanol.
Topics: Buffers; Ethanol; Free Radical Scavengers; Hydrogen Bonding; Hydrogen-Ion Concentration; Kinetics; Mannitol; Models, Chemical; Nitrates; Oxidants; Spectrophotometry, Ultraviolet | 1998 |
Inactivation of tyrosine hydroxylase by nitration following exposure to peroxynitrite and 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP).
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Electrophoresis, Gel, Two-Dimensional; Mice; Nitrates; PC12 Cells; Rats; Superoxide Dismutase; Tyrosine 3-Monooxygenase | 1998 |
Mitochondrial creatine kinase is a prime target of peroxynitrite-induced modification and inactivation.
Topics: Animals; Chickens; Creatine Kinase; Isoenzymes; Mitochondria, Muscle; Nitrates; Oxidative Phosphorylation; Substrate Specificity | 1998 |
Nitric oxide production in human macrophagic cells phagocytizing opsonized zymosan: direct characterization by measurement of the luminol dependent chemiluminescence.
Topics: Calcitriol; Cell Differentiation; Cell-Free System; Free Radical Scavengers; Guanidines; Humans; Immunoglobulin E; Immunoglobulin G; Leukemia, Monocytic, Acute; Luminescent Measurements; Luminol; Lymphoma, Large B-Cell, Diffuse; Macrophage Activation; Macrophages; Neoplastic Stem Cells; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; omega-N-Methylarginine; Opsonin Proteins; Phagocytosis; Superoxide Dismutase; Superoxides; Tretinoin; Tumor Cells, Cultured; Xanthine; Xanthine Oxidase; Zymosan | 1998 |
Peroxynitrite causes aspartate release from dissociated rat cerebellar granule neurones.
Topics: Animals; Aspartic Acid; Brain Ischemia; Calcium; Cerebellar Cortex; Dithiothreitol; Egtazic Acid; Glutamic Acid; Ion Transport; Kainic Acid; Membrane Proteins; Nerve Tissue Proteins; Neurons; Nitrates; Nitric Oxide; Oxidants; Oxidation-Reduction; Rats; Rats, Wistar; Sodium; Sulfhydryl Compounds; Superoxides; Tetrodotoxin | 1998 |
Xanthine oxidase reaction with nitric oxide and peroxynitrite.
Topics: Animals; Blood Proteins; Catalase; Cattle; Cells, Cultured; Endothelium, Vascular; Free Radicals; Glutathione; In Vitro Techniques; Nitrates; Nitric Oxide; Nitroso Compounds; Oxidants; S-Nitrosoglutathione; Uric Acid; Xanthine; Xanthine Oxidase | 1998 |
Effect of carotenoids on the respiratory burst of rat peritoneal macrophages.
Topics: Animals; Arginine; Carotenoids; Free Radical Scavengers; Hydroxyl Radical; Lipid Peroxidation; Luminescent Measurements; Macrophages, Peritoneal; Male; Nitrates; Nitric Oxide; Rats; Rats, Wistar; Respiratory Burst; Superoxides; Tetradecanoylphorbol Acetate | 1998 |
Modification of tissue factor by peroxynitrite influences its procoagulant activity.
Topics: Coagulants; Membrane Proteins; Monocytes; Nitrates; Oxidants; Recombinant Proteins; Thromboplastin; Tyrosine | 1998 |
Asbestos inhalation induces reactive nitrogen species and nitrotyrosine formation in the lungs and pleura of the rat.
Topics: Animals; Asbestos, Crocidolite; Asbestos, Serpentine; Bronchoalveolar Lavage; Cells, Cultured; Enzyme-Linked Immunosorbent Assay; Inhalation Exposure; Lung; Macrophages; Macrophages, Alveolar; Male; Nitrates; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrogen Dioxide; Pleura; Pleural Effusion; Rats; Rats, Inbred F344; Reactive Oxygen Species; Tyrosine | 1998 |
Role of peroxynitrite and neuronal nitric oxide synthase in the activation of poly(ADP-ribose) synthetase in a murine model of cerebral ischemia-reperfusion.
Topics: Animals; Brain Ischemia; Enzyme Activation; Mice; Mice, Knockout; Nerve Tissue Proteins; Neurons; Nitrates; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Oxidants; Poly(ADP-ribose) Polymerases; Reperfusion Injury | 1998 |
Genetic disruption of poly (ADP-ribose) synthetase inhibits the expression of P-selectin and intercellular adhesion molecule-1 in myocardial ischemia/reperfusion injury.
Topics: Animals; Cell Movement; Coronary Disease; Endothelium, Vascular; Fibroblasts; Gene Deletion; Humans; Intercellular Adhesion Molecule-1; Mice; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocardium; Neutrophils; Nitrates; P-Selectin; Poly(ADP-ribose) Polymerases | 1998 |
Forum: reactive species of peroxynitrite.
Topics: Nitrates; Oxidants; Reactive Oxygen Species | 1998 |
Radical nature of peroxynitrite reactivity.
Topics: Chemical Phenomena; Chemistry, Physical; Electrons; Free Radicals; Hydroxyl Radical; Kinetics; Nitrates; Oxidants; Stereoisomerism | 1998 |
Peroxynitrite uncloaked?
Topics: Free Radicals; Hydrogen-Ion Concentration; Isomerism; Kinetics; Nitrates; Oxidants; Tyrosine | 1998 |
The nature of reactive species in systems that produce peroxynitrite.
Topics: Carbon Dioxide; Free Radicals; Glutathione Peroxidase; Hemoglobins; Hydroxyl Radical; Nitrates; Nitrites; Oxidants; Peroxidase | 1998 |
Peroxynitrite reactions and diffusion in biology.
Topics: Animals; Carbon Dioxide; Diffusion; Hydroxyl Radical; Membranes; Mitochondria; Nitrates; Nitrites; Nitroso Compounds; Oxidants; Oxidation-Reduction | 1998 |
Evidence for in vivo peroxynitrite production in human chronic hepatitis.
Topics: Adult; Antibodies; Antibody Specificity; Female; Hepatitis B, Chronic; Hepatitis C, Chronic; Humans; Immunohistochemistry; Liver Cirrhosis; Male; Middle Aged; Nitrates; Tyrosine | 1998 |
Nitration of the low molecular weight neurofilament is equivalent in sporadic amyotrophic lateral sclerosis and control cervical spinal cord.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amyotrophic Lateral Sclerosis; Blotting, Western; Humans; Isoelectric Focusing; Middle Aged; Neurofilament Proteins; Nitrates; Precipitin Tests; Spinal Cord; Tyrosine | 1998 |
Detection of superoxide radicals and peroxynitrite by 1-hydroxy-4-phosphonooxy-2,2,6,6-tetramethylpiperidine: quantification of extracellular superoxide radicals formation.
Topics: Electron Spin Resonance Spectroscopy; Free Radical Scavengers; Free Radicals; Kinetics; Molecular Structure; Nitrates; Nitroglycerin; Organophosphates; Piperidines; Pyrrolidines; Spin Labels; Superoxide Dismutase; Superoxides; Xanthine Oxidase | 1998 |
Neopterin derivatives modulate the nitration of tyrosine by peroxynitrite.
Topics: Hydrogen-Ion Concentration; Neopterin; Nitrates; Nitro Compounds; Pteridines; Pterins; Spectrophotometry; Tyrosine | 1998 |
Diffusion and reaction of nitric oxide in suspension cell cultures.
Topics: Animals; Cell Membrane; Cells, Cultured; Culture Media; Diffusion; Kinetics; Macrophage Activation; Macrophages; Models, Biological; Mutagens; Nitrates; Nitric Oxide; Nitrosamines; Oxidation-Reduction; Superoxides | 1998 |
Enhancement of peroxynitrite-induced apoptosis in PC12 cells by fibroblast growth factor-1 and nerve growth factor requires p21Ras activation and is suppressed by Bcl-2.
Topics: Animals; Apoptosis; Drug Synergism; Fibroblast Growth Factor 1; Mutation; Nerve Growth Factors; Nitrates; PC12 Cells; Proto-Oncogene Proteins c-bcl-2; Proto-Oncogene Proteins p21(ras); Rats | 1998 |
Role of peroxynitrite in the vasoactive and cytotoxic effects of Alzheimer's beta-amyloid1-40 peptide.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Antioxidants; Aorta, Thoracic; Cell Survival; Cells, Cultured; Endothelium, Vascular; Free Radical Scavengers; Guanylate Cyclase; Male; Metalloporphyrins; Muscle Relaxation; Muscle, Smooth, Vascular; Nitrates; Oxidants; Oxidative Stress; Peptide Fragments; Rats; Rats, Sprague-Dawley; Superoxide Dismutase | 1998 |
Phosphoinositide hydrolysis activated by muscarinic or glutamatergic, but not adrenergic, receptors is impaired in ApoE-deficient mice and by hydrogen peroxide and peroxynitrite.
Topics: Animals; Apolipoproteins E; Hydrogen Peroxide; Hydrolysis; In Vitro Techniques; Mice; Mice, Knockout; Nitrates; Oxidants; Oxidative Stress; Phosphatidylinositols; Receptors, Adrenergic; Receptors, Glutamate; Receptors, Muscarinic; Signal Transduction | 1998 |
Attenuation of vascular relaxation after development of tachyphylaxis to peroxynitrite in vivo.
Topics: Acetylcholine; Animals; Blood Pressure; Bradykinin; Hemodynamics; Hydrazines; Nitrates; Nitric Oxide; Oxidants; Rats; Rats, Sprague-Dawley; Regional Blood Flow; Splanchnic Circulation; Tachyphylaxis; Vascular Resistance; Vasodilation | 1998 |
Mechanisms of cardioprotection by peroxynitrite in myocardial ischemia and reperfusion injury.
Topics: Animals; Cardiotonic Agents; Cats; Cell Adhesion; Coronary Vessels; Endothelium, Vascular; In Vitro Techniques; Leukocyte Count; Male; Muscle, Smooth, Vascular; Myocardial Ischemia; Myocardial Reperfusion; Myocardial Reperfusion Injury; Neutrophils; Nitrates; Oxidants; P-Selectin; Rats; Time Factors; Vasoconstriction | 1998 |
Peroxynitrite production by human neutrophils, monocytes and lymphocytes challenged with lipopolysaccharide.
Topics: Adult; Enzyme Inhibitors; Female; Guanidines; Humans; Lipopolysaccharides; Lymphocytes; Male; Middle Aged; Monocytes; Neutrophils; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide Synthase; Oxidants; Oxidation-Reduction; Rhodamines; Shock, Septic | 1998 |
Formation of nitrated and hydroxylated aromatic compounds from benzene and peroxynitrite, a possible mechanism of benzene genotoxicity.
Topics: Benzene; Carcinogens; Dose-Response Relationship, Drug; Humans; Neutrophils; Nitrates; Nitrobenzenes; Nitrophenols; Phenol; Spectrophotometry, Ultraviolet; Tetradecanoylphorbol Acetate | 1998 |
Peroxynitrite formation within the central nervous system in active multiple sclerosis.
Topics: Central Nervous System; Humans; Immunohistochemistry; Inflammation; Multiple Sclerosis; Nervous System Diseases; Nitrates; Nitrites; Recurrence; Tyrosine | 1998 |
Reaction of nitric oxide with superoxide inhibits basolateral K+ channels in the rat CCD.
Topics: Animals; Cell Membrane; Cyclic GMP; Ditiocarb; In Vitro Techniques; Kidney Cortex; Kidney Tubules, Collecting; Membrane Potentials; Nitrates; Nitric Oxide; Nitroprusside; Patch-Clamp Techniques; Penicillamine; Potassium Channels; Potassium Channels, Calcium-Activated; Pyrogallol; Rats; Rats, Sprague-Dawley; S-Nitroso-N-Acetylpenicillamine; Small-Conductance Calcium-Activated Potassium Channels; Superoxides | 1998 |
Comparison of antioxidant activities of aminoguanidine, methylguanidine and guanidine by luminol-enhanced chemiluminescence.
Topics: Antioxidants; Ferrous Compounds; Free Radical Scavengers; Free Radicals; Guanidine; Guanidines; Humans; Hydrogen Peroxide; Hypochlorous Acid; In Vitro Techniques; Leukocytes; Luminescent Measurements; Luminol; Methylguanidine; Nitrates | 1998 |
Protective effect of melatonin in a non-septic shock model induced by zymosan in the rat.
Topics: Acute Disease; Animals; Antioxidants; Chemical and Drug Induced Liver Injury; Chemotaxis, Leukocyte; Dose-Response Relationship, Drug; Free Radical Scavengers; Ileum; Immunoenzyme Techniques; Intestinal Diseases; Intestinal Mucosa; Liver Diseases; Lung Diseases; Male; Melatonin; Neutrophils; Nitrates; Nitrites; Peritonitis; Peroxidase; Random Allocation; Rats; Rats, Sprague-Dawley; Saccharomyces cerevisiae; Zymosan | 1998 |
Formation of reactive oxygen species by pentaerithrityltetranitrate and glyceryl trinitrate in vitro and development of nitrate tolerance.
Topics: Animals; Blood Platelets; Cells, Cultured; Cyclic GMP; Drug Tolerance; Endothelium, Vascular; Hydroxyl Radical; Muscle, Smooth, Vascular; Nitrates; Nitroglycerin; Pentaerythritol Tetranitrate; Reactive Oxygen Species; Spin Trapping; Superoxides; Swine | 1998 |
Asbestos fibers and interleukin-1 upregulate the formation of reactive nitrogen species in rat pleural mesothelial cells.
Topics: Animals; Asbestos; Cells, Cultured; Culture Media, Conditioned; Cytochalasin B; Enzyme Induction; Epithelium; Free Radicals; Gene Expression Regulation, Enzymologic; Immunohistochemistry; Interleukin-1; L-Lactate Dehydrogenase; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Pleura; Rats; Rats, Inbred F344; Recombinant Proteins | 1998 |
Dichlorodihydrofluorescein and dihydrorhodamine 123 are sensitive indicators of peroxynitrite in vitro: implications for intracellular measurement of reactive nitrogen and oxygen species.
Topics: Fluoresceins; Indicators and Reagents; Nitrates; Nitrogen; Oxidation-Reduction; Reactive Oxygen Species; Rhodamines; Spectrophotometry, Ultraviolet | 1997 |
Expression of inducible nitric oxide synthase and formation of peroxynitrite in posttransplant obliterative bronchiolitis.
Topics: Bronchiolitis Obliterans; Heart-Lung Transplantation; Humans; Lung; Lung Transplantation; Nitrates; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Oxidants; Postoperative Complications | 1998 |
Endogenous peroxynitrite generation causes a subsequent suppression of coronary arterial contraction to serotonin.
Topics: Animals; Arteries; Cattle; Coronary Vessels; Free Radical Scavengers; In Vitro Techniques; Luminescent Measurements; Muscle Contraction; Nitrates; Nitric Oxide; Serotonin | 1997 |
Myeloperoxidase and horseradish peroxidase catalyze tyrosine nitration in proteins from nitrite and hydrogen peroxide.
Topics: Animals; Catalase; Catalysis; Horseradish Peroxidase; Hydrogen Peroxide; Hypochlorous Acid; Male; Myocardium; Nitrates; Nitrites; Peroxidase; Rats; Serum Albumin, Bovine; Tyrosine | 1998 |
Differential sensitivity of the tyrosyl radical of mouse ribonucleotide reductase to nitric oxide and peroxynitrite.
Topics: Animals; Coculture Techniques; DNA Replication; Free Radicals; Hydrogen Peroxide; Macrophage Activation; Macrophages, Peritoneal; Mice; NADPH Oxidases; Nitrates; Nitric Oxide; Ribonucleotide Reductases; Spectrophotometry, Atomic; Tumor Cells, Cultured; Tyrosine | 1998 |
The reaction of peroxynitrite with zeaxanthin.
Topics: beta Carotene; Dimyristoylphosphatidylcholine; Freeze Fracturing; Hydrogen-Ion Concentration; Kinetics; Liposomes; Microscopy, Electron; Nitrates; Phosphatidylcholines; Spectrophotometry, Atomic; Xanthophylls; Zeaxanthins | 1998 |
Effect of nitric oxide on hemoprotein-catalyzed oxidative reactions.
Topics: Catalase; Dose-Response Relationship, Drug; Heme; Hemoglobins; Hydrogen Peroxide; Hypoxanthine; Myoglobin; Nitrates; Nitric Oxide; Oxidants; Oxidation-Reduction; Rhodamines; Spectrometry, Fluorescence; Spectrophotometry; Superoxide Dismutase; Superoxides; Xanthine Oxidase | 1998 |
Expression of thioredoxin is enhanced in atherosclerotic plaques and during neointima formation in rat arteries.
Topics: Animals; Arteriosclerosis; Carotid Arteries; Catheterization; Humans; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Nude; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Oxidants; Rats; Rats, Wistar; RNA, Messenger; Thioredoxins; Tumor Cells, Cultured; Tunica Intima; Tyrosine | 1998 |
Procyanidins extracted from pine bark protect alpha-tocopherol in ECV 304 endothelial cells challenged by activated RAW 264.7 macrophages: role of nitric oxide and peroxynitrite.
Topics: Animals; Cell Line; Coculture Techniques; Endothelium, Vascular; Flavonoids; Humans; Macrophage Activation; Mice; Nitrates; Nitric Oxide; Plant Extracts; Trees; Vitamin E | 1998 |
Effects of peroxynitrite on plasma components of the reverse cholesterol transport pathway.
Topics: Biological Transport; Cholesterol Esters; Cholesterol, HDL; Humans; Macrophages; Nitrates; Phosphatidylcholine-Sterol O-Acyltransferase | 1998 |
Protective effects of 5-iodo-6-amino-1,2-benzopyrone, an inhibitor of poly(ADP-ribose) synthetase against peroxynitrite-induced glial damage and stroke development.
Topics: Animals; Cell Death; Cerebral Infarction; Coumarins; Enzyme Inhibitors; Ischemia; L-Lactate Dehydrogenase; Male; Mice; Mitochondria; Neuroglia; Neurons; Nitrates; Poly(ADP-ribose) Polymerase Inhibitors; Rats; Tumor Cells, Cultured | 1998 |
Reduction of tyrosine nitration after N(omega)-nitro-L-arginine-methylester treatment of mice with traumatic brain injury.
Topics: Animals; Brain Injuries; Cerebral Cortex; Enzyme Inhibitors; Immunohistochemistry; Male; Mice; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide Synthase; Tyrosine | 1998 |
Proinflammatory cytokines depress cardiac efficiency by a nitric oxide-dependent mechanism.
Topics: Animals; Coronary Circulation; Dexamethasone; Enzyme Inhibitors; Free Radical Scavengers; Guanidines; Heart Conduction System; Interferon-gamma; Interleukin-1; Kinetics; Male; Myocardial Contraction; Myocardium; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Oxygen Consumption; Rats; Rats, Sprague-Dawley; Tumor Necrosis Factor-alpha | 1998 |
Inhibition of peroxynitrite-mediated tyrosine nitration by a novel pyrrolopyrimidine antioxidant.
Topics: Antioxidants; Erythrocyte Membrane; Humans; Nitrates; Oxidative Stress; Pyrimidines; Pyrrolidines; Tyrosine | 1998 |
Inhaled nitric oxide primes lung macrophages to produce reactive oxygen and nitrogen intermediates.
Topics: Administration, Inhalation; Animals; Antibodies; Bronchoalveolar Lavage Fluid; Dose-Response Relationship, Drug; Epithelial Cells; Interferon-gamma; Lipopolysaccharides; Lung; Macrophages, Alveolar; Male; Mice; Mice, Inbred BALB C; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrogen; Oxidants; Proteins; Pulmonary Alveoli; Reactive Oxygen Species; Superoxides; Tyrosine; Vasodilator Agents | 1998 |
Propofol reacts with peroxynitrite to form a phenoxyl radical: demonstration by electron spin resonance.
Topics: Anesthetics; Antioxidants; Electron Spin Resonance Spectroscopy; Free Radical Scavengers; Free Radicals; Hydrogen-Ion Concentration; In Vitro Techniques; Models, Biological; Nitrates; Oxidation-Reduction; Phenols; Propofol; Spectrophotometry, Ultraviolet; Spin Labels | 1998 |
Nitrosation of uric acid by peroxynitrite. Formation of a vasoactive nitric oxide donor.
Topics: Animals; Aorta, Thoracic; Chromatography, High Pressure Liquid; Electrochemistry; Endothelium, Vascular; Humans; Imidazoles; In Vitro Techniques; Isometric Contraction; Kinetics; Mass Spectrometry; Muscle, Smooth, Vascular; Nitrates; Nitric Oxide; Oxidants; Oxyhemoglobins; Photolysis; Rats; Spectrophotometry; Uric Acid; Vasodilation | 1998 |
Enhancement of peroxynitrite-evoked acetylcholine release by hydroxyl radical scavengers from mouse cerebral cortical neurons.
Topics: Acetylcholine; Animals; Calcium; Cells, Cultured; Cerebral Cortex; Cricetinae; Dose-Response Relationship, Drug; Exocytosis; Free Radical Scavengers; Hydroxyl Radical; Mice; Nerve Tissue Proteins; Neurons; Nitrates; Oxidants; Thiourea | 1998 |
Role of constitutive nitric oxide synthase and peroxynitrite production in a rat model of splanchnic artery occlusion shock.
Topics: Analysis of Variance; Animals; Constriction; Enzyme Inhibitors; Ileum; Immunohistochemistry; Male; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; Rats; Rats, Sprague-Dawley; Shock; Splanchnic Circulation; Tyrosine | 1998 |
Peroxynitrite modulates MnSOD gene expression in lung epithelial cells.
Topics: Animals; Blotting, Northern; Cell Line; Epithelial Cells; Gene Expression; Humans; Hydrogen Peroxide; Luciferases; Lung; Molsidomine; Nitrates; Nitric Oxide; Nitrites; Rats; Recombinant Fusion Proteins; RNA, Messenger; Superoxide Dismutase | 1998 |
Role of peroxynitrite and poly (ADP-ribosyl) synthetase activation in cardiovascular derangement induced by zymosan in the rat.
Topics: Animals; Aortic Diseases; Benzamides; Enzyme Activation; Enzyme Inhibitors; Immunohistochemistry; Injections, Intraperitoneal; Male; Niacinamide; Nitrates; Oxidants; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Rats; Rats, Sprague-Dawley; Shock, Cardiogenic; Tyrosine; Zymosan | 1998 |
Nitrosation by peroxynitrite: use of phenol as a probe.
Topics: Carbon Dioxide; Free Radicals; Hydrogen Peroxide; Hydrogen-Ion Concentration; Ions; Kinetics; Molecular Probes; Nitrates; Nitrogen Oxides; Nitrosation; Nitroso Compounds; Phenol | 1998 |
Protective effect of melatonin on cellular energy depletion mediated by peroxynitrite and poly (ADP-ribose) synthetase activation in a non-septic shock model induced by zymosan in the rat.
Topics: Animals; Cell Respiration; Cells, Cultured; DNA Damage; Energy Metabolism; Enzyme Activation; Macrophages, Peritoneal; Male; Melatonin; NAD; Nitrates; Nitric Oxide; Oxidation-Reduction; Poly(ADP-ribose) Polymerases; Rats; Rats, Sprague-Dawley; Rhodamines; Shock; Zymosan | 1998 |
Poly(ADP-ribose) synthetase activation mediates mitochondrial injury during oxidant-induced cell death.
Topics: Animals; Calcium; Cell Death; Dicarbethoxydihydrocollidine; Enzyme Activation; Intracellular Membranes; Membrane Potentials; Mice; Mice, Knockout; Mitochondria; Necrosis; Nitrates; Oxidants; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Reactive Oxygen Species; T-Lymphocytes; Thymus Gland | 1998 |
Lack of tyrosine nitration by peroxynitrite generated at physiological pH.
Topics: Carbon Dioxide; Free Radicals; Hydrogen-Ion Concentration; Models, Chemical; Molsidomine; Nitrates; Nitrogen Oxides; Spermine; Tyrosine; Xanthine Oxidase | 1998 |
Peroxynitrite generation might explain elevated glutamate and aspartate levels in multiple sclerosis cerebrospinal fluid.
Topics: Animals; Aspartic Acid; Glutamic Acid; Humans; Models, Biological; Multiple Sclerosis; Neurodegenerative Diseases; Nitrates; Nitric Oxide; Receptors, N-Methyl-D-Aspartate | 1998 |
Peroxynitrite-induced thymocyte apoptosis: the role of caspases and poly (ADP-ribose) synthetase (PARS) activation.
Topics: Animals; Apoptosis; Benzamides; Caspase 1; Caspase 3; Caspases; Cell Death; Cells, Cultured; Cysteine Endopeptidases; DNA Fragmentation; Enzyme Activation; Enzyme Inhibitors; Flow Cytometry; Hydrogen Peroxide; Immunohistochemistry; Mice; Nitrates; Nitric Oxide; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Thymus Gland; Tyrosine | 1998 |
Comparison of the effects of nitric oxide and peroxynitrite on the 12-lipoxygenase and cyclooxygenase metabolism of arachidonic acid in rabbit platelets.
Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; Animals; Arachidonate 12-Lipoxygenase; Arachidonic Acid; Blood Platelets; Catalase; Cyclooxygenase Inhibitors; Fatty Acids, Unsaturated; Lipoxygenase Inhibitors; Male; Nitrates; Nitric Oxide; Prostaglandin-Endoperoxide Synthases; Rabbits; Superoxides; Thromboxane B2; Triazenes; Xanthine; Xanthine Oxidase | 1998 |
Potentiation of N-methyl-D-aspartate-mediated neurotoxicity by immunostimulated murine microglia.
Topics: Animals; Apoptosis; Catalase; Cerebellum; Coculture Techniques; DNA Fragmentation; In Situ Nick-End Labeling; Interferon-gamma; L-Lactate Dehydrogenase; Lipopolysaccharides; Mice; Microglia; Molsidomine; N-Methylaspartate; Neurons; Nitrates; Nitric Oxide; Nitroarginine; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Superoxide Dismutase | 1998 |
EPC-K1 attenuates peroxynitrite-induced apoptosis in cerebellar granule cells.
Topics: Adenosine Triphosphate; Animals; Antioxidants; Apoptosis; Ascorbic Acid; Cell Survival; Cells, Cultured; Cerebellum; DNA Fragmentation; Lipid Peroxidation; Membrane Fluidity; Neurons; Nitrates; Rats; Rats, Wistar; Thiobarbituric Acid Reactive Substances; Vitamin E | 1998 |
The reaction of melatonin with peroxynitrite: formation of melatonin radical cation and absence of stable nitrated products.
Topics: Bicarbonates; Free Radicals; Melatonin; Models, Biological; Nitrates | 1998 |
Comparative resistance of the 20S and 26S proteasome to oxidative stress.
Topics: Coumarins; Cysteine Endopeptidases; Erythrocytes; Ferritins; Fluorescent Dyes; Humans; Hydrogen Peroxide; K562 Cells; Kinetics; Multienzyme Complexes; Nitrates; Oligopeptides; Oxidants; Oxidative Stress; Peptide Hydrolases; Proteasome Endopeptidase Complex; Sodium Hypochlorite; Substrate Specificity | 1998 |
Removal of hydroxyl radical facilitates Ca2+-dependent [3H]GABA release by peroxynitrite.
Topics: Animals; Calcium; Cells, Cultured; Cerebral Cortex; Dose-Response Relationship, Drug; Fetus; Free Radical Scavengers; gamma-Aminobutyric Acid; Hydroxyl Radical; Mannitol; Mice; Neurons; Nitrates; Thiourea; Tritium; Urea; Uric Acid | 1998 |
Peroxynitrite is not a major mediator of endothelial cell injury by activated neutrophils in vitro.
Topics: Animals; Antibodies, Monoclonal; Cattle; CD18 Antigens; Cells, Cultured; Coculture Techniques; Deferoxamine; Dimethyl Sulfoxide; Endothelium, Vascular; Humans; Neutrophil Activation; Neutrophils; Nitrates; Nitric Oxide Synthase; Nitrites; Ornithine; Penicillamine; Superoxide Dismutase; Tetradecanoylphorbol Acetate; Tyrosine | 1998 |
The effect of nitric oxide and peroxynitrite on apoptosis in human polymorphonuclear leukocytes.
Topics: Annexin A5; Apoptosis; Flow Cytometry; Humans; Lipopolysaccharides; Lung; Molsidomine; Neutrophils; Nitrates; Nitric Oxide; Triazoles | 1998 |
Beta-carotene with vitamins E and C offers synergistic cell protection against NOx.
Topics: Antioxidants; Ascorbic Acid; beta Carotene; Cell Survival; Drug Synergism; Free Radicals; Humans; Jurkat Cells; Lymphocytes; Nitrates; Nitrogen Dioxide; Oxidants; Vitamin E | 1998 |
Increased metabolism of peroxynitrite-modified [125I] beta-VLDL by monocytes from hypercholesterolemic rabbits.
Topics: Animals; Cholesterol; Cholesterol, Dietary; Hypercholesterolemia; Lipoproteins, VLDL; Male; Monocytes; Nitrates; Rabbits; Triglycerides | 1998 |
Formation of S-nitrosothiols via direct nucleophilic nitrosation of thiols by peroxynitrite with elimination of hydrogen peroxide.
Topics: Ascorbic Acid; Cells, Cultured; Chromatography, High Pressure Liquid; Electron Spin Resonance Spectroscopy; Glutathione; Humans; Hydrogen Peroxide; Hydrogen-Ion Concentration; Kinetics; Luminescent Measurements; Nitrates; Nitric Oxide | 1998 |
Effects of superoxide and peroxynitrite on vascular tension in the human umbilical artery.
Topics: Female; Fetal Blood; Free Radicals; Humans; Nitrates; Nitric Oxide; Oxidants; Placenta; Pregnancy; Superoxides; Umbilical Arteries; Vascular Resistance | 1998 |
Nitric oxide and peroxynitrite-dependent aconitase inactivation and iron-regulatory protein-1 activation in mammalian fibroblasts.
Topics: Aconitate Hydratase; Animals; Cell Line; Cricetinae; Cricetulus; Enzyme Activation; Fibroblasts; Glutathione; Intracellular Fluid; Iron Regulatory Protein 1; Iron-Regulatory Proteins; Iron-Sulfur Proteins; Nitrates; Nitric Oxide; RNA-Binding Proteins; RNA, Messenger | 1998 |
Interaction of peroxynitrite with mitochondrial cytochrome oxidase. Catalytic production of nitric oxide and irreversible inhibition of enzyme activity.
Topics: Animals; Catalytic Domain; Cattle; Copper; Electron Transport Complex IV; Heme; Inactivation, Metabolic; Mitochondria; Nitrates; Nitric Oxide; Oxidation-Reduction; Oxygen Consumption; Proteolipids; Solubility | 1998 |
Nitric oxide donor-induced hyperpermeability of cultured intestinal epithelial monolayers: role of superoxide radical, hydroxyl radical, and peroxynitrite.
Topics: Antioxidants; Caco-2 Cells; Epithelial Cells; Free Radical Scavengers; Glutathione; Humans; Hydroxyl Radical; Intestinal Absorption; Intestines; Kinetics; Molsidomine; Nitrates; Nitric Oxide; Nitric Oxide Donors; Penicillamine; Permeability; Superoxide Dismutase; Superoxides | 1998 |
Sensitivity of the synaptic membrane Na+/Ca2+ exchanger and the expressed NCX1 isoform to reactive oxygen species.
Topics: Amidines; Animals; Brain; CHO Cells; Cricetinae; Gene Expression; In Vitro Techniques; Kinetics; Male; Nitrates; Oxidants; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Sodium-Calcium Exchanger; Synaptic Membranes; Transfection | 1998 |
Peroxynitrite is a contractile agonist of cerebral artery smooth muscle cells.
Topics: Animals; Cerebral Arteries; Male; Muscle, Smooth, Vascular; Myocardial Reperfusion Injury; Nitrates; Oxidants; Rats; Rats, Wistar; Vasoconstriction | 1998 |
Nitric oxide and peroxynitrite in lipid peroxidation.
Topics: Animals; Antioxidants; Humans; Inflammation; Lipid Peroxidation; Lipid Peroxides; Lipoproteins, LDL; Nitrates; Nitric Oxide; Oxidants; Reactive Oxygen Species | 1998 |
Concurrent generation of nitric oxide and superoxide inhibits proteoglycan synthesis in bovine articular chondrocytes: involvement of peroxynitrite.
Topics: Animals; Cartilage, Articular; Cattle; Chondrocytes; Immunohistochemistry; Interleukin-1; Molsidomine; Nitrates; Nitric Oxide; Proteoglycans; Superoxides | 1998 |
Peroxynitrite mediates IL-8 gene expression and production in lipopolysaccharide-stimulated human whole blood.
Topics: Adult; Female; Gene Expression Regulation; Guanidines; Humans; Hydroxyl Radical; Interleukin-8; Lipopolysaccharides; Male; Middle Aged; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Pyrrolidines; RNA, Messenger; Thiocarbamates | 1998 |
Interleukin 1beta decreases prostacyclin synthase activity in rat mesangial cells via endogenous peroxynitrite formation.
Topics: Animals; Antioxidants; Arachidonic Acid; Chelating Agents; Cytochrome P-450 Enzyme System; Free Radical Scavengers; Glomerular Mesangium; Interleukin-1; Intramolecular Oxidoreductases; Nitrates; Nitric Oxide; omega-N-Methylarginine; Prostaglandin H2; Prostaglandins H; Rats; Superoxide Dismutase | 1998 |
Peroxynitrite induces covalent dimerization of epidermal growth factor receptors in A431 epidermoid carcinoma cells.
Topics: Carbodiimides; Carcinoma, Squamous Cell; Cell Division; Cross-Linking Reagents; Dimerization; ErbB Receptors; Humans; Isoenzymes; Kinetics; Molecular Weight; Nitrates; Phospholipase C gamma; Phosphorylation; Phosphotyrosine; Tumor Cells, Cultured; Type C Phospholipases | 1998 |
S-Nitroglutathione, a product of the reaction between peroxynitrite and glutathione that generates nitric oxide.
Topics: Chromatography, High Pressure Liquid; Glucose; Glutathione; Mass Spectrometry; Nitrates; Nitric Oxide; Nitro Compounds; Oxidants; Spectrophotometry, Ultraviolet | 1998 |
Peroxynitrite oxidises catechols to o-quinones.
Topics: Caffeic Acids; Catechols; Chromatography, High Pressure Liquid; Cysteine; Glutathione; Hydrogen-Ion Concentration; Isomerism; Nitrates; Oxidation-Reduction; Quinones; Sulfhydryl Compounds | 1998 |
Phosphatidylinositol 3-kinase is a target for protein tyrosine nitration.
Topics: Animals; Cell Line; Mice; Molecular Weight; Nitrates; Nitric Oxide Donors; Nitrogen Oxides; Phosphatidylinositol 3-Kinases; Protein Conformation; Proteins; Spermine; Tyrosine | 1998 |
Toxic effects of sulphite in combination with peroxynitrite on neuronal cells.
Topics: Animals; Cell Line; Cell Survival; DNA Fragmentation; Drug Combinations; Neurons; Nitrates; Oxidants; Rats; Sulfites; Tyrosine | 1998 |
Hydroxyguanidines inhibit peroxynitrite-induced oxidation.
Topics: Arginine; Benzoic Acid; Cell Line; Free Radical Scavengers; Guanidines; Hydroxylamines; Hydroxylation; Macrophages; Nitrates; Oxidation-Reduction; Rhodamines | 1998 |
Nitrated SP-A does not enhance adherence of Pneumocystis carinii to alveolar macrophages.
Topics: Animals; Egtazic Acid; Humans; Macrophages, Alveolar; Nitrates; Phagocytosis; Pneumocystis; Proteolipids; Pulmonary Surfactant-Associated Protein A; Pulmonary Surfactant-Associated Proteins; Pulmonary Surfactants; Rats; Rats, Inbred Lew | 1998 |
Superoxide released from neutrophils causes a reduction in nitric oxide gas.
Topics: Animals; Cell Line; Cell Survival; Epithelial Cells; Gases; Humans; Hydrogen-Ion Concentration; Lung; Mice; Neutrophils; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Oxidants; RNA, Messenger; Superoxides; Tyrosine | 1998 |
Peroxynitrite formation and apoptosis in transgenic sickle cell mouse kidneys.
Topics: Anemia, Sickle Cell; Animals; Apoptosis; Blotting, Western; Immunohistochemistry; Kidney; Mice; Mice, Inbred C57BL; Mice, Transgenic; Nitrates; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Tyrosine | 1998 |
The mechanism of the nitric oxide-mediated enhancement of tert-butylhydroperoxide-induced DNA single strand breakage.
Topics: Caffeine; Calcium; Cytochromes c1; DNA Damage; DNA, Single-Stranded; Electron Transport; Humans; Mitochondria; NAD(P)H Dehydrogenase (Quinone); Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Penicillamine; tert-Butylhydroperoxide; Tumor Cells, Cultured; U937 Cells; Ubiquinone | 1998 |
New aspects in the reaction mechanism of phenol with peroxynitrite: the role of phenoxy radicals.
Topics: Anisoles; Free Radicals; Hydrogen-Ion Concentration; Kinetics; Molecular Structure; Nitrates; Nitrites; Nitrophenols; Oxygen; Phenol; Phenols; Tyrosine | 1998 |
Glyceraldehyde-3-phosphate dehydrogenase inactivation by peroxynitrite.
Topics: Animals; Arsenites; Binding, Competitive; Cysteine; Dithiothreitol; Enzyme Inhibitors; Free Radical Scavengers; Glutathione; Glyceraldehyde 3-Phosphate; Glyceraldehyde-3-Phosphate Dehydrogenases; Hydrogen-Ion Concentration; Iodobenzoates; Kinetics; Methionine; Muscle, Skeletal; Nitrates; Nitric Oxide; Oxidation-Reduction; Rabbits; Sulfhydryl Compounds | 1998 |
Kinetic study of the reaction of glutathione peroxidase with peroxynitrite.
Topics: Glutathione Peroxidase; Indicators and Reagents; Kinetics; Nitrates; Oxidation-Reduction | 1998 |
Mercaptoethylguanidine, a combined inhibitor of nitric oxide synthase and peroxynitrite scavenger, reduces trinitrobenzene sulfonic acid-induced colonic damage in rats.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Body Weight; Colitis; Enzyme Inhibitors; Free Radical Scavengers; Guanidines; Immunohistochemistry; Male; Nitrates; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Rats; Rats, Wistar; Trinitrobenzenesulfonic Acid; Tyrosine | 1998 |
Antioxidant and pro-oxidant actions of flavonoids: effects on DNA damage induced by nitric oxide, peroxynitrite and nitroxyl anion.
Topics: Antioxidants; Chromatography, High Pressure Liquid; DNA Damage; DNA, Single-Stranded; Flavins; Free Radical Scavengers; Free Radicals; Guanine; Molecular Structure; Nitrates; Nitric Oxide; Nitrites; Oxidants; Phenols; Plasmids | 1998 |
Crucial role of apopain in the peroxynitrite-induced apoptotic DNA fragmentation.
Topics: Apoptosis; Caspase 3; Caspases; Cell Survival; DNA Fragmentation; Enzyme Activation; Enzyme Inhibitors; Flow Cytometry; HL-60 Cells; Humans; Nitrates; Peptides; Phosphatidylserines; Poly(ADP-ribose) Polymerase Inhibitors | 1998 |
Kinetics of peroxynitrite reaction with amino acids and human serum albumin.
Topics: Amino Acids; Carbon Dioxide; Hot Temperature; Hydrogen-Ion Concentration; Kinetics; Nitrates; Serum Albumin; Sulfhydryl Compounds | 1999 |
Intra-coronary administration of L-arginine aggravates myocardial stunning through production of peroxynitrite in dogs.
Topics: Analysis of Variance; Animals; Arginine; Chromatography, High Pressure Liquid; Dogs; Enzyme Inhibitors; Female; Immunohistochemistry; Isomerism; Lipid Peroxidation; Male; Malondialdehyde; Microdialysis; Myocardial Contraction; Myocardial Stunning; Myocardium; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Oxidative Stress; Random Allocation; Superoxide Dismutase; Tyrosine | 1998 |
Nitric oxide inhibits tissue factor synthesis, expression and activity in human monocytes by prior formation of peroxynitrite.
Topics: Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Flow Cytometry; Free Radical Scavengers; Gene Expression Regulation; Humans; Lipopolysaccharides; Monocytes; Nitrates; Nitric Oxide; Oxidants; Thromboplastin | 1998 |
Protective effects of melatonin in zymosan-activated plasma-induced paw inflammation.
Topics: Animals; Anti-Inflammatory Agents; Biomarkers; Dose-Response Relationship, Drug; Edema; Foot; Free Radical Scavengers; Male; Melatonin; Nitrates; Oxidants; Plasma; Rats; Rats, Wistar; Tyrosine | 1998 |
HIV-1 protein Tat induces apoptosis of hippocampal neurons by a mechanism involving caspase activation, calcium overload, and oxidative stress.
Topics: AIDS Dementia Complex; Amino Acid Chloromethyl Ketones; Animals; Apoptosis; Calcium; Caspase Inhibitors; Caspases; Cells, Cultured; Chelating Agents; Cysteine Proteinase Inhibitors; Cytoplasm; Egtazic Acid; Enzyme Activation; Gene Products, tat; Hippocampus; HIV-1; Membrane Potentials; Mitochondria; Neurons; Nitrates; Nitric Oxide; Oxidants; Oxidative Stress; Rats; Rats, Sprague-Dawley; tat Gene Products, Human Immunodeficiency Virus | 1998 |
Antiinflammatory actions of cat's claw: the role of NF-kappaB.
Topics: Animals; Anti-Inflammatory Agents; Apoptosis; Cell Survival; Cells, Cultured; Electrophoresis; Enzyme Activation; Gene Expression Regulation; HT29 Cells; Humans; Indomethacin; Inflammation; Male; Metallothionein; NF-kappa B; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Oxidative Stress; Peroxidase; Plant Extracts; Rats; Rats, Sprague-Dawley; RNA, Messenger | 1998 |
The peroxynitrite generator, SIN-1, becomes a nitric oxide donor in the presence of electron acceptors.
Topics: Animals; Cyclic N-Oxides; Free Radical Scavengers; Hemeproteins; Humans; Imidazoles; Kidney; Liver; Molsidomine; Myocardium; Nitrates; Nitric Oxide Donors; Oxidants; Rats | 1999 |
Pulmonary vascular stress from carbon monoxide.
Topics: Animals; Capillaries; Carbon Monoxide; Electron Spin Resonance Spectroscopy; Enzyme Inhibitors; Hydrogen Peroxide; Kinetics; Leukocytes; Lung; Male; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Wistar; Tyrosine; Vascular Diseases | 1999 |
Peroxynitrite-induced alterations in synaptosomal membrane proteins: insight into oxidative stress in Alzheimer's disease.
Topics: Alzheimer Disease; Animals; Cell Survival; Cells, Cultured; Cyclic N-Oxides; Cytosol; Gerbillinae; Glutathione; Hippocampus; Male; Membrane Proteins; Neurons; Nitrates; Nitric Oxide; Oxidants; Oxidation-Reduction; Oxidative Stress; Spin Labels; Synaptosomes | 1999 |
Priming of human neutrophils by peroxynitrite: potential role in enhancement of the local inflammatory response.
Topics: Antioxidants; Blood Proteins; Calcium; Cells, Cultured; Humans; Inflammation; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Nitrates; Oxidants; Pyrimidines; Pyrrolidines; Stimulation, Chemical; Superoxides; Tetradecanoylphorbol Acetate; Tyrosine | 1999 |
The effect of peroxynitrite on sphincter of Oddi motility.
Topics: Animals; Carbachol; Catalase; Electric Stimulation; Enzyme Inhibitors; Female; Gastrointestinal Motility; In Vitro Techniques; Male; Muscle Contraction; Muscle Relaxation; Nitrates; Nitric Oxide Synthase; Nitroarginine; Opossums; Oxyhemoglobins; Sphincter of Oddi; Superoxide Dismutase | 1999 |
Peroxynitrite reacts with methemoglobin to generate globin-bound free radical species. Implications for vascular injury.
Topics: Blood Vessels; Electron Spin Resonance Spectroscopy; Free Radicals; Globins; Humans; Methemoglobin; Nitrates; Oxidants; Oxidative Stress | 1998 |
Beneficial effects of Mn(III)tetrakis (4-benzoic acid) porphyrin (MnTBAP), a superoxide dismutase mimetic, in carrageenan-induced pleurisy.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; DNA Damage; Energy Metabolism; Free Radical Scavengers; Lung; Male; Metalloporphyrins; Neutrophils; Nitrates; Nitric Oxide; Pleurisy; Rats; Rats, Sprague-Dawley; Superoxide Dismutase; Superoxides | 1999 |
Nitric oxide-dependent and independent effects on human platelets treated with peroxynitrite.
Topics: Blood Platelets; Calcium; Collagen; Cyclic GMP; Dose-Response Relationship, Drug; Enzyme Inhibitors; Flow Cytometry; Free Radical Scavengers; Guanylate Cyclase; Humans; Immunohistochemistry; Nitrates; Nitric Oxide; Oxadiazoles; Oxidants; Oxyhemoglobins; P-Selectin; Platelet Activation; Quinoxalines | 1998 |
Nitration of unsaturated fatty acids by nitric oxide-derived reactive nitrogen species peroxynitrite, nitrous acid, nitrogen dioxide, and nitronium ion.
Topics: Chromatography, High Pressure Liquid; Chromatography, Liquid; Fatty Acids, Unsaturated; Hydrogen-Ion Concentration; Linoleic Acid; Linoleic Acids; Lipid Peroxides; Magnetic Resonance Spectroscopy; Mass Spectrometry; Nitrates; Nitric Oxide; Nitrogen Dioxide; Nitrous Acid; Oxidants; Oxidation-Reduction | 1999 |
Peroxynitrite production and activation of poly (adenosine diphosphate-ribose) synthetase in spinal cord injury.
Topics: Adenosine Diphosphate; Animals; Contusions; Female; Laminectomy; Nitrates; Poly(ADP-ribose) Polymerases; Rats; Rats, Sprague-Dawley; Spinal Cord; Spinal Cord Injuries; Tyrosine | 1999 |
Specific inhibition of iNOS decreases the intestinal mucosal peroxynitrite level and improves the barrier function after thermal injury.
Topics: Animals; Antioxidants; Bacterial Translocation; Body Surface Area; Burns; Coloring Agents; Enzyme Inhibitors; Female; Intestinal Mucosa; Intestine, Small; Isothiuronium; Liver; Lymph Nodes; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Oxidants; Rats; Rats, Sprague-Dawley; Spleen; Superoxides; Tyrosine | 1998 |
Use of repair endonucleases to assess DNA damage by peroxynitrite.
Topics: Animals; CHO Cells; Cricetinae; DNA Damage; DNA Repair; Endodeoxyribonucleases; Nitrates; Oxidants; Oxidative Stress | 1999 |
Interaction of carotenoids and tocopherols with peroxynitrite.
Topics: Animals; Carotenoids; Humans; Lipid Peroxidation; Lipoproteins, LDL; Nitrates; Oxidation-Reduction; Vitamin E | 1999 |
Mitochondria, nitric oxide, and peroxynitrite.
Topics: Animals; Calcium; Cell Membrane; Membrane Potentials; Mitochondria, Liver; Nitrates; Nitric Oxide; Rats | 1999 |
Application of authentic peroxynitrite to biological materials.
Topics: Animals; Biocompatible Materials; Calcium; Cells, Cultured; Fluorescent Dyes; Heart; Hydrogen-Ion Concentration; Membrane Fluidity; Mice; Myocardial Contraction; Nitrates; Oxidants; Perfusion | 1999 |
Antioxidant properties of the decarboxylated dimer of aminoethylcysteine ketimine: assessment of its ability to scavenge peroxynitrite.
Topics: alpha 1-Antitrypsin; Amino Acids, Sulfur; Antioxidants; Decarboxylation; Dimerization; Free Radical Scavengers; Humans; Lipoproteins, LDL; Nitrates; Oxidation-Reduction; Tyrosine | 1998 |
Kinetic and spectroscopic characterization of an intermediate peroxynitrite complex in the nitrogen monoxide induced oxidation of oxyhemoglobin.
Topics: Flow Injection Analysis; Humans; Hydrogen-Ion Concentration; Nitrates; Nitric Oxide; Oxidation-Reduction; Oxyhemoglobins; Spectrophotometry | 1999 |
Evidence for peroxynitrite formation in the vasculature of women with preeclampsia.
Topics: Adult; Biopsy; Cesarean Section; Endothelium, Vascular; Female; Humans; Hysterectomy; Immunohistochemistry; Muscle, Smooth, Vascular; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Oxidants; Oxidative Stress; Pre-Eclampsia; Pregnancy; Superoxide Dismutase; Tyrosine | 1999 |
Peroxynitrite-mediated attenuation of alpha- and beta-adrenoceptor agonist-induced vascular responses in vivo.
Topics: Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Animals; Arginine Vasopressin; Epinephrine; Hemodynamics; Isoproterenol; Nitrates; Norepinephrine; Oxidants; Phenylephrine; Rats; Rats, Sprague-Dawley; Vasoconstriction; Vasoconstrictor Agents | 1999 |
Applications of electron paramagnetic resonance spectroscopy to study interactions of iron proteins in cells with nitric oxide.
Topics: Animals; Bacteria; Cysteine; Electron Spin Resonance Spectroscopy; Food Preservation; Hemeproteins; Hemoglobins; Mammals; Mitochondria, Liver; Nitrates; Nitric Oxide; Nitrites; Nitroprusside; Parkinson Disease; Shock, Septic; Substantia Nigra | 1998 |
Dielectric resonator-based flow and stopped-flow EPR with rapid field scanning: A methodology for increasing kinetic information.
Topics: Antioxidants; Cytochrome c Group; Cytochromes c; Dehydroascorbic Acid; Electron Spin Resonance Spectroscopy; Free Radicals; Magnetics; Nitrates; Nitrogen Oxides; Oxidants; Protein Folding; Pulsatile Flow; Saccharomyces cerevisiae Proteins; Spin Labels | 1999 |
Release of cytochrome c from heart mitochondria is induced by high Ca2+ and peroxynitrite and is responsible for Ca(2+)-induced inhibition of substrate oxidation.
Topics: Animals; Calcium; Cytochrome c Group; Intracellular Membranes; Male; Mitochondria, Heart; Myocardial Ischemia; Nitrates; Oxidation-Reduction; Oxidative Phosphorylation; Rats; Rats, Wistar | 1999 |
Attenuated acute cardiac rejection in NOS2 -/- recipients correlates with reduced apoptosis.
Topics: Animals; Apoptosis; Caspase 3; Caspases; Coumarins; Cysteine Proteinase Inhibitors; DNA Primers; Enzyme Activation; Gene Expression Regulation, Enzymologic; Graft Rejection; Heart Transplantation; In Situ Nick-End Labeling; Mice; Mice, Inbred CBA; Mice, Knockout; Muscle Fibers, Skeletal; Myocardium; Nitrates; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Oligopeptides; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerases; Proteins; RNA, Messenger; Transplantation Immunology; Transplantation, Homologous; Tumor Suppressor Protein p53; Tyrosine | 1999 |
Overexpression of CuZn superoxide dismutase protects RAW 264.7 macrophages against nitric oxide cytotoxicity.
Topics: Animals; Apoptosis; Base Sequence; Cell Line; DNA Primers; Glutathione; Humans; Macrophages; Mice; Nitrates; Nitric Oxide; Superoxide Dismutase | 1999 |
Peroxynitrite induces long-lived tyrosyl radical(s) in oxyhemoglobin of red blood cells through a reaction involving CO2 and a ferryl species.
Topics: Carbon Dioxide; Electron Spin Resonance Spectroscopy; Erythrocytes; Ferric Compounds; Free Radicals; Heme; Hemoglobins; Humans; Hydrogen Peroxide; Iron; Methemoglobin; Metmyoglobin; Nitrates; Oxidants; Oxygen; Oxyhemoglobins; Tyrosine | 1999 |
Effect of *NO on the decomposition of peroxynitrite: reaction of N2O3 with ONOO-.
Topics: Hydrogen-Ion Concentration; Hydroxyl Radical; Kinetics; Nitrates; Nitric Oxide; Nitrous Acid; Oxidants; Oxidation-Reduction; Peroxynitrous Acid; Spectrophotometry; Superoxides | 1999 |
Peroxynitrite affects Ca2+ transport in Trypanosoma cruzi.
Topics: Adenine Nucleotides; Adenosine Triphosphate; Animals; Biological Transport; Calcium; Calcium-Transporting ATPases; Cell Membrane Permeability; Energy Metabolism; Homeostasis; Membrane Potentials; Mitochondria; Nitrates; Trypanosoma cruzi | 1999 |
Protective effect of N-acetylcysteine on cellular energy depletion in a non-septic shock model induced by zymosan in the rat.
Topics: Acetylcysteine; Animals; Cell Membrane Permeability; Disease Models, Animal; DNA Damage; Dose-Response Relationship, Drug; Energy Metabolism; Free Radical Scavengers; Macrophages, Peritoneal; Male; NAD; Nitrates; Nitric Oxide; Rats; Rats, Sprague-Dawley; Sepsis; Shock; Tyrosine; Zymosan | 1999 |
Synergism of nitric oxide and iron in killing the transformed murine oligodendrocyte cell line N20.1.
Topics: Animals; Cell Death; Cell Line; Coloring Agents; Culture Media, Serum-Free; DNA Fragmentation; Drug Synergism; Immunohistochemistry; Iron; Kinetics; Mice; Nitrates; Nitric Oxide; Nitric Oxide Donors; Nitroprusside; Oligodendroglia; Oxidants; Penicillamine; S-Nitroso-N-Acetylpenicillamine; Trypan Blue | 1999 |
Peroxynitrite causes proton leak in brain mitochondria.
Topics: Animals; Brain; Lipid Peroxidation; Membrane Potentials; Mitochondria; Nitrates; Protons; Rats | 1998 |
Peroxynitrite formation during rat hepatic allograft rejection.
Topics: Animals; Blood Transfusion; Enzyme Inhibitors; Graft Rejection; Graft Survival; Liver Transplantation; Male; Nitrates; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; omega-N-Methylarginine; Rats; Rats, Inbred ACI; Rats, Inbred Lew; RNA, Messenger; Tacrolimus; Tissue Donors; Transplantation, Homologous; Transplantation, Isogeneic; Tyrosine | 1999 |
The effect of alpha-tocopherol on the nitration of gamma-tocopherol by peroxynitrite.
Topics: Chelating Agents; Dose-Response Relationship, Drug; Enzyme Inhibitors; Liposomes; Molsidomine; Nitrates; Oxidants; Pentetic Acid; Stereoisomerism; Tyrosine; Vitamin E | 1999 |
Cyclooxygenase-2 is widely expressed in atherosclerotic lesions affecting native and transplanted human coronary arteries and colocalizes with inducible nitric oxide synthase and nitrotyrosine particularly in macrophages.
Topics: Animals; Arteriosclerosis; Coronary Artery Bypass; Coronary Vessels; Cyclooxygenase 2; Graft Survival; Humans; Isoenzymes; Macrophages; Membrane Proteins; Nitrates; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrogen Compounds; Prostaglandin-Endoperoxide Synthases; Rabbits; Tyrosine | 1999 |
A novel superoxide dismutase-based trap for peroxynitrite used to detect entry of peroxynitrite into erythrocyte ghosts.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Animals; Blotting, Western; Cattle; Erythrocyte Membrane; Humans; In Vitro Techniques; Isothiocyanates; Kinetics; Membrane Proteins; Mutation; Nitrates; Oxidants; Superoxide Dismutase; Thiocyanates | 1999 |
Mycobacterium tuberculosis KatG is a peroxynitritase.
Topics: Bacterial Proteins; Catalysis; Heme; Hemeproteins; Hydrogen-Ion Concentration; Kinetics; Mycobacterium tuberculosis; Nitrates; Peroxidases; Spectrophotometry; Temperature | 1999 |
Effects of endotoxin on human myocardial contractility involvement of nitric oxide and peroxynitrite.
Topics: Adult; Culture Techniques; Dose-Response Relationship, Drug; Endotoxins; Female; Heart Failure; Humans; Isoproterenol; Male; Middle Aged; Myocardial Contraction; Nitrates; Nitric Oxide; Nitric Oxide Synthase | 1999 |
Rapid induction of NF-kappaB binding during liver cell isolation and culture: inhibition by L-NAME indicates a role for nitric oxide synthase.
Topics: Acetylcysteine; Animals; Antioxidants; Binding, Competitive; Cell Culture Techniques; Cell Separation; Cell Survival; Cells, Cultured; Chromans; Dithiothreitol; Enzyme Inhibitors; Liver; Male; NF-kappa B; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide Synthase; Oligonucleotides; Protein Binding; Rats; Rats, Sprague-Dawley; Response Elements; Time Factors | 1999 |
Acceleration of adhesion of cancer cells and neutrophils to endothelial cells in the absence of de novo protein synthesis: possible implication for involvement of hydroxyl radicals.
Topics: Catalase; Cell Adhesion; Cell Membrane; Chelating Agents; Colonic Neoplasms; Cycloheximide; Dactinomycin; Edetic Acid; Endothelium, Vascular; Humans; Hydrogen Peroxide; Hydroxyl Radical; Hypoxanthine; Neutrophils; Nitrates; Protein Biosynthesis; Reactive Oxygen Species; Superoxide Dismutase; Tumor Cells, Cultured; Xanthine Oxidase | 1999 |
Peroxynitrite inhibits T lymphocyte activation and proliferation by promoting impairment of tyrosine phosphorylation and peroxynitrite-driven apoptotic death.
Topics: Apoptosis; CD3 Complex; Cell Division; Cells, Cultured; Dose-Response Relationship, Immunologic; Humans; Immunosuppressive Agents; Lymph Nodes; Lymphocyte Activation; Metalloporphyrins; Monocytes; Nitrates; Nitric Oxide Synthase; Phosphorylation; Proteins; Superoxide Dismutase; T-Lymphocytes; Time Factors; Tyrosine | 1999 |
Detection of 3-nitrotyrosine in human platelets exposed to peroxynitrite by a new gas chromatography/mass spectrometry assay.
Topics: Blood Platelets; Fluorobenzenes; Gas Chromatography-Mass Spectrometry; Humans; Nitrates; Nitrogen Dioxide; Sensitivity and Specificity; Tyrosine | 1998 |
Nitric oxide products degrade chondroitin sulfates.
Topics: Chondroitin Sulfates; Chromatography, Gel; Dermatan Sulfate; Glycosaminoglycans; Nitrates; Nitric Oxide; Penicillamine | 1998 |
Oxidative stress occurs in perfused rat liver at low oxygen tension by mechanisms involving peroxynitrite.
Topics: Animals; Ethanol; Female; Free Radicals; Glycogen; Hydrogen-Ion Concentration; In Vitro Techniques; Liver; Nitrates; Oxidants; Oxidative Stress; Oxygen; Perfusion; Rats; Rats, Sprague-Dawley; Tyrosine | 1999 |
In vivo modulation of rodent glutathione and its role in peroxynitrite-induced neocortical synaptosomal membrane protein damage.
Topics: Animals; Cerebral Cortex; Electron Spin Resonance Spectroscopy; Gerbillinae; Glutathione; Male; Membrane Proteins; Nitrates; Oxidative Stress; Protein Conformation; Synaptic Membranes | 1999 |
Interaction of peroxynitrite and hydrogen peroxide with dinitrosyl iron complexes containing thiol ligands in vitro.
Topics: Cysteine; Electron Spin Resonance Spectroscopy; Glutathione; Hydrogen Peroxide; Iron; Ligands; Nitrates; Nitroso Compounds; Oxidation-Reduction; Serum Albumin, Bovine; Sulfhydryl Compounds | 1999 |
Inhibition of poly(ADP-ribose) synthetase (PARS) and protection against peroxynitrite-induced cytotoxicity by zinc chelation.
Topics: Animals; Caspase 3; Caspases; Cell Death; Chelating Agents; Cytochrome c Group; DNA Fragmentation; Enzyme Activation; Ethylenediamines; Male; Mice; Mitochondria; Nitrates; Oxidants; Oxidation-Reduction; Phosphatidylserines; Poly(ADP-ribose) Polymerase Inhibitors; Thymus Gland | 1999 |
Inhibition of bronchoprotective effects of beta2-adrenoceptor agonists by peroxynitrite in guinea pig airways.
Topics: Acetylcholine; Adrenergic beta-Agonists; Airway Resistance; Albuterol; Animals; Bronchoconstriction; Colforsin; Guinea Pigs; Isoproterenol; Male; Molsidomine; Nitrates; Penicillamine; Receptors, Adrenergic, beta-1 | 1999 |
A kinetic model of the system: tyrosyl radical-nitrogen oxide-superoxide ion.
Topics: Arteriosclerosis; Free Radicals; Humans; Ions; Lipid Peroxidation; Lipoproteins, LDL; Models, Chemical; Nitrates; Nitrogen Oxides; Superoxides; Tyrosine | 1999 |
Direct EPR detection of the carbonate radical anion produced from peroxynitrite and carbon dioxide.
Topics: Carbon Dioxide; Carbonates; Electron Spin Resonance Spectroscopy; Free Radicals; Hydrogen-Ion Concentration; Nitrates | 1999 |
Quantification of total oxidant scavenging capacity of antioxidants for peroxynitrite, peroxyl radicals, and hydroxyl radicals.
Topics: Amidines; Antioxidants; Ascorbic Acid; Chromatography, Gas; Free Radical Scavengers; Free Radicals; Hydroxyl Radical; Methionine; Molsidomine; Nitrates; Nitric Oxide Donors; Oxidants; Oxidation-Reduction; Peroxides | 1999 |
Increased peroxynitrite activity in AIDS dementia complex: implications for the neuropathogenesis of HIV-1 infection.
Topics: Acquired Immunodeficiency Syndrome; Adult; Aged; AIDS Dementia Complex; Brain Chemistry; Female; HIV Infections; HIV-1; Humans; Immunohistochemistry; Interleukin-1; Interleukin-10; Macrophages; Male; Middle Aged; Nitrates; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; RNA, Messenger; Superoxide Dismutase; Superoxides; Tyrosine | 1999 |
Conformation of peroxynitrite: determination by crystallographic analysis.
Topics: Crystallography; Molecular Conformation; Nitrates; Nitrites | 1999 |
Formation of phospholipid hydroperoxides and its inhibition by alpha-tocopherol in rat brain synaptosomes induced by peroxynitrite.
Topics: Acetophenones; Animals; Antioxidants; Brain; Dose-Response Relationship, Drug; Hydrogen Peroxide; Male; Molsidomine; Nitrates; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipases A; Phospholipases A2; Phospholipids; Rats; Rats, Wistar; Superoxide Dismutase; Synaptosomes; Time Factors; Vitamin E | 1999 |
Peroxynitrite induces haem oxygenase-1 in vascular endothelial cells: a link to apoptosis.
Topics: Acetylcysteine; Animals; Antioxidants; Aorta; Apoptosis; Bilirubin; Cattle; Cell Line; Cell Survival; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Induction; Free Radical Scavengers; Heme Oxygenase (Decyclizing); Heme Oxygenase-1; Hemin; Metalloporphyrins; Nitrates; Protoporphyrins; Thiourea; Time Factors; Uric Acid | 1999 |
Metabolic impairment induces oxidative stress, compromises inflammatory responses, and inactivates a key mitochondrial enzyme in microglia.
Topics: Animals; Azides; Cell Survival; Cells, Cultured; Enzyme Activation; Glutamate Dehydrogenase; Inflammation; Ketoglutarate Dehydrogenase Complex; Lipopolysaccharides; Mice; Mice, Inbred C57BL; Microglia; Mitochondria; Nitrates; Nitric Oxide; Oxidative Stress; Oxidoreductases; Oxygen Consumption; Reactive Oxygen Species; Tyrosine | 1999 |
Prostaglandin endoperoxide-dependent vasospasm in bovine coronary arteries after nitration of prostacyclin synthase.
Topics: Angiotensin II; Animals; Carbon Radioisotopes; Cattle; Coronary Vasospasm; Coronary Vessels; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dinoprostone; Epoprostenol; Immunohistochemistry; In Vitro Techniques; Intramolecular Oxidoreductases; Nitrates; Oxidants; Potassium Chloride; Prostaglandin Antagonists; Prostaglandin H2; Prostaglandins; Prostaglandins H; Proteins; Tyrosine; Vasoconstriction; Vasodilation | 1999 |
Activation pattern of mitogen-activated protein kinases elicited by peroxynitrite: attenuation by selenite supplementation.
Topics: Animals; Calcium-Calmodulin-Dependent Protein Kinases; Cell Line; Epithelium; Glutathione Peroxidase; Hydrogen Peroxide; Liver; Nitrates; Nitric Oxide; Phosphorylation; Rats; Sodium Selenite; Time Factors; Tyrosine | 1999 |
Inhibition of peroxynitrite dependent DNA base modification and tyrosine nitration by the extra virgin olive oil-derived antioxidant hydroxytyrosol.
Topics: Animals; Antioxidants; Cattle; Chronic Disease; DNA; DNA Damage; Humans; Hybrid Cells; Mice; Neuroblastoma; Neurons; Nitrates; Nitric Oxide; Olive Oil; Oxidants; Phenylethyl Alcohol; Plant Oils; Rats; Retina; Superoxides; Tyrosine | 1999 |
The relative importance of HO* and ONOO- in mediating the toxicity of O*-.
Topics: Chemical Phenomena; Chemistry, Physical; Escherichia coli; Hydroxyl Radical; Nitrates; Oxidants; Oxidation-Reduction; Superoxides | 1999 |
Surfactant protein A mediates mycoplasmacidal activity of alveolar macrophages by production of peroxynitrite.
Topics: Animals; Cells, Cultured; Macrophage Activation; Macrophages, Alveolar; Mice; Mice, Inbred C57BL; Mycoplasma; Mycoplasma Infections; Nitrates; Proteolipids; Pulmonary Surfactant-Associated Protein A; Pulmonary Surfactant-Associated Proteins; Pulmonary Surfactants | 1999 |
Generation of peroxynitrite and apoptosis in placenta of patients with chorioamnionitis: possible implications in placental abruption.
Topics: Adult; Apoptosis; Chorioamnionitis; Female; Humans; Immunohistochemistry; Nitrates; Oxidants; Placenta; Pregnancy; Rupture, Spontaneous | 1999 |
The oxidative and nitrosative chemistry of the nitric oxide/superoxide reaction in the presence of bicarbonate.
Topics: 2-Naphthylamine; Bicarbonates; Glutathione; Models, Chemical; Nitrates; Nitric Oxide; Nitrosation; Oxidation-Reduction; Rhodamines; Superoxides; Xanthine Oxidase | 1999 |
Evidence for peroxynitrite formation during S-nitrosoglutathione photolysis in air saturated solutions.
Topics: Glutathione; Hydrogen-Ion Concentration; Nitrates; Nitroso Compounds; Photolysis; S-Nitrosoglutathione; Solutions | 1999 |
Contrasting roles for nitric oxide and peroxynitrite in the peroxidation of myelin lipids.
Topics: Animals; Central Nervous System; Dinoprost; Encephalomyelitis, Autoimmune, Experimental; F2-Isoprostanes; Lipid Peroxidation; Mice; Molsidomine; Myelin Proteins; Myelin Sheath; Nitrates; Nitric Oxide; Nitric Oxide Donors; Oxidants; Penicillamine | 1999 |
In vivo disposition of 3-nitro-L-tyrosine in rats: implications on tracking systemic peroxynitrite exposure.
Topics: Animals; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Half-Life; Infusions, Intravenous; Male; Nitrates; Oxidants; Rats; Rats, Sprague-Dawley; Tissue Distribution; Tyrosine | 1999 |
Relationships between nitric oxide, nitroxyl ion, nitrosonium cation and peroxynitrite.
Topics: Free Radicals; Hydrogen-Ion Concentration; Iron; Mercaptoethanol; Nitrates; Nitric Oxide; Nitric Oxide Donors; Nitrogen Oxides; Nitrosation; Nitroso Compounds; Oxidation-Reduction; Photochemistry; S-Nitrosothiols | 1999 |
Inhaled nitric oxide in ARDS: is the question closed?
Topics: Administration, Inhalation; Bronchodilator Agents; Humans; Nitrates; Nitric Oxide; Oxidants; Practice Guidelines as Topic; Research Design; Respiratory Distress Syndrome | 1999 |
Modulation of peroxynitrite- and hypochlorous acid-induced inactivation of alpha1-antiproteinase by mercaptoethylguanidine.
Topics: alpha 1-Antitrypsin; Dose-Response Relationship, Drug; Enzyme Inhibitors; Guanidines; Humans; Hypochlorous Acid; Nitrates; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Tyrosine | 1999 |
Catalytic scavenging of peroxynitrite by isomeric Mn(III) N-methylpyridylporphyrins in the presence of reductants.
Topics: Ascorbic Acid; Catalysis; Free Radical Scavengers; Glutathione; Hydrogen-Ion Concentration; Isomerism; Kinetics; Metalloporphyrins; Nitrates; Oxidants; Oxidation-Reduction; Porphyrins; Reducing Agents; Tyrosine; Uric Acid | 1999 |
Peroxynitrite-induced reactions of synthetic oligonucleotides containing 8-oxoguanine.
Topics: Chromatography, Liquid; DNA; Guanine; Indicators and Reagents; Mass Spectrometry; Nitrates; Oligonucleotides; Oxamic Acid; Oxidants | 1999 |
Octamer-dimer transitions of mitochondrial creatine kinase in heart disease.
Topics: Animals; Creatine Kinase; Dimerization; In Vitro Techniques; Male; Mitochondria, Heart; Myocardial Infarction; Myocardial Ischemia; Nitrates; Perfusion; Protein Conformation; Rats; Rats, Wistar | 1999 |
The role of reactive nitrogen/oxygen intermediates in cytokine-induced trophoblast apoptosis.
Topics: Apoptosis; Cells, Cultured; Cytokines; Enzyme Inhibitors; Female; Free Radical Scavengers; Humans; Interferon-gamma; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrogen; Oxidants; Pregnancy; Reactive Oxygen Species; Superoxide Dismutase; Superoxides; Trophoblasts; Tumor Necrosis Factor-alpha | 1999 |
Evidence for iNOS-dependent peroxynitrite production in diabetic platelets.
Topics: Adult; Arginine; Blood Platelets; Blotting, Western; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Female; Fluorescent Dyes; Humans; Male; Microscopy, Confocal; Middle Aged; Nitrates; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Spectrometry, Fluorescence | 1999 |
Tyrosine modifications and inactivation of active site manganese superoxide dismutase mutant (Y34F) by peroxynitrite.
Topics: Catalytic Domain; Humans; Mutation; Nitrates; Recombinant Proteins; Superoxide Dismutase; Tyrosine | 1999 |
Inhibitory effects of nitric oxide on the expression and activity of aromatase in human granulosa cells.
Topics: Adult; Aromatase; Aromatase Inhibitors; Cells, Cultured; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Female; Gene Expression Regulation; Granulosa Cells; Humans; Isoquinolines; Nitrates; Nitric Oxide; Penicillamine; Protein Kinase C; Sodium Nitrite; Sulfonamides; Tetradecanoylphorbol Acetate; Transcription, Genetic | 1999 |
High levels of peroxynitrite are generated in the lungs of irradiated mice given cyclophosphamide and allogeneic T cells. A potential mechanism of injury after marrow transplantation.
Topics: Animals; Bone Marrow Transplantation; Bronchoalveolar Lavage Fluid; Cyclophosphamide; Disease Models, Animal; Female; L-Lactate Dehydrogenase; Lung; Macrophages, Alveolar; Mice; Mice, Inbred C57BL; Models, Biological; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; T-Lymphocytes; Time Factors; Tyrosine | 1999 |
Insulin secretion, DNA damage, and apoptosis in human and rat islets of Langerhans following exposure to nitric oxide, peroxynitrite, and cytokines.
Topics: Adult; Animals; Apoptosis; Cytokines; DNA Damage; Female; Humans; Insulin; Insulin Secretion; Islets of Langerhans; Nitrates; Nitric Oxide; Rats; Rats, Sprague-Dawley | 1998 |
Chemiluminescent detection of oxidants in vascular tissue. Lucigenin but not coelenterazine enhances superoxide formation.
Topics: Acetylcholine; Acridines; Animals; Cells, Cultured; Cytochrome c Group; Endothelium, Vascular; Firefly Luciferin; Hydrogen Peroxide; Imidazoles; Luminescent Measurements; Male; NAD; Nitrates; Oxidants; Oxygen Consumption; Pyrazines; Rats; Rats, Sprague-Dawley; Superoxides; Vasodilator Agents; Xanthine Oxidase | 1999 |
Effect of nitric oxide donors on renal tubular epithelial cell-matrix adhesion.
Topics: Animals; Cell Adhesion; Cell Line; Chlorocebus aethiops; Collagen; Epithelial Cells; Fibronectins; Free Radical Scavengers; Kidney Tubules; LLC-PK1 Cells; Molsidomine; Nitrates; Nitric Oxide; Nitric Oxide Donors; Opossums; Superoxides; Swine | 1999 |
Peroxynitrite scavenging by different antioxidants. Part I: convenient assay.
Topics: Antioxidants; Carbon Dioxide; Coloring Agents; Free Radical Scavengers; Kinetics; Metals; Nitrates; Oxidants; Plant Extracts; Reactive Oxygen Species | 1999 |
Protein modification during biological aging: selective tyrosine nitration of the SERCA2a isoform of the sarcoplasmic reticulum Ca2+-ATPase in skeletal muscle.
Topics: Aging; Amino Acid Sequence; Animals; Biological Transport; Calcium; Calcium-Transporting ATPases; Cysteine; Endopeptidases; Isoenzymes; Muscle Fibers, Fast-Twitch; Muscle Fibers, Slow-Twitch; Nitrates; Nitric Oxide; Oxygen; Peptide Fragments; Protein Processing, Post-Translational; Rats; Rats, Inbred F344; Sarcoplasmic Reticulum; Sulfhydryl Compounds; Tyrosine | 1999 |
Autoinhibition of neuronal nitric oxide synthase: distinct effects of reactive nitrogen and oxygen species on enzyme activity.
Topics: Animals; Arginine; Cerebellum; Citrulline; Feedback; Free Radical Scavengers; Glutathione; Hydrogen Peroxide; Inhibitory Concentration 50; Kinetics; Methemoglobin; Methionine; Nitrates; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitrogen; Reactive Oxygen Species; Superoxide Dismutase; Swine | 1999 |
Peroxynitrite reacts with biological nitrogen-containing cyclic molecules by a radical pathway, as demonstrated by ultraweak luminescence coupled with ESR technique.
Topics: Electron Spin Resonance Spectroscopy; Free Radicals; Heterocyclic Compounds; Imidazoles; Kinetics; Luminescent Measurements; Molecular Structure; Nitrates; Nitrogen Oxides; Pyridines; Serotonin; Spin Labels; Tryptophan | 1999 |
Peroxynitrite contributes to spontaneous loss of cardiac efficiency in isolated working rat hearts.
Topics: Animals; Cycloheximide; Energy Metabolism; Heart; In Vitro Techniques; Male; Myocardium; Nitrates; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Protein Synthesis Inhibitors; Rats; Rats, Sprague-Dawley; Xanthine Dehydrogenase; Xanthine Oxidase | 1999 |
Cellular applications of a sensitive and selective fiber-optic nitric oxide biosensor based on a dye-labeled heme domain of soluble guanylate cyclase.
Topics: Animals; Biosensing Techniques; Enzyme Inhibitors; Enzyme Stability; Fiber Optic Technology; Fluorescent Dyes; Guanylate Cyclase; Heme; Hydrogen Peroxide; Interferon-gamma; Lipopolysaccharides; Macrophages; Mice; Mice, Inbred BALB C; Microspheres; Nitrates; Nitric Oxide; omega-N-Methylarginine; Optical Fibers; Sensitivity and Specificity; Solubility; Superoxides | 1999 |
DNA damage in deoxynucleosides and oligonucleotides treated with peroxynitrite.
Topics: Deoxyribonuclease (Pyrimidine Dimer); Deoxyribonucleosides; DNA Damage; DNA Glycosylases; DNA Repair; DNA-Formamidopyrimidine Glycosylase; Endodeoxyribonucleases; Guanine; N-Glycosyl Hydrolases; Nitrates; Nucleic Acid Conformation; Oligonucleotides; Oxidants; Substrate Specificity; Uracil-DNA Glycosidase | 1999 |
Reaction of peroxynitrite with melatonin: A mechanistic study.
Topics: Bicarbonates; Catalysis; Free Radicals; Hydrogen-Ion Concentration; Kinetics; Melatonin; Nitrates; Oxidants; Oxidation-Reduction | 1999 |
S-nitrosothiols are stored by platelets and released during platelet-neutrophil interactions.
Topics: Arginase; Blood Platelets; Cell Adhesion; Glutathione; Humans; In Vitro Techniques; Neutrophil Activation; Neutrophils; Nitrates; Nitric Oxide; Nitroso Compounds; S-Nitrosoglutathione; Superoxides; Xanthine Oxidase | 1999 |
Analysis of 3-nitrotyrosine in biological fluids and protein hydrolyzates by high-performance liquid chromatography using a postseparation, on-line reduction column and electrochemical detection: results with various nitrating agents.
Topics: Chromatography, High Pressure Liquid; Electrochemistry; Humans; Hypochlorous Acid; Indicators and Reagents; Molsidomine; Nitrates; Nitrites; Nitrogen Oxides; Serum Albumin, Bovine; Sodium Nitrite; Spectrophotometry, Ultraviolet; Spermine; Tyrosine | 1999 |
Peroxynitrite reaction with heme proteins.
Topics: Catalysis; Cytochrome P-450 Enzyme System; Hemeproteins; Hydrogen-Ion Concentration; Iron; Kinetics; Nitrates; Oxidoreductases; Peroxidases | 1999 |
Inhibition of GTP binding to Rac2 by peroxynitrite: potential role for tyrosine modification.
Topics: Animals; Binding Sites; Fluorescent Dyes; Free Radicals; GTP-Binding Proteins; Guanosine Triphosphate; In Vitro Techniques; Nitrates; Oxidants; rac GTP-Binding Proteins; Reactive Oxygen Species; Recombinant Proteins; Tyrosine | 1999 |
Pretreatment of mice with macrophage inactivators decreases acetaminophen hepatotoxicity and the formation of reactive oxygen and nitrogen species.
Topics: Acetaminophen; Alanine Transaminase; Animals; Anti-Inflammatory Agents; Aspartate Aminotransferases; Dextran Sulfate; Gadolinium; Kupffer Cells; Liver; Macrophage Activation; Macrophages; Male; Mice; Mice, Inbred Strains; Necrosis; Nitrates; Nitric Oxide; Oxidants; Oxidative Stress; Reactive Oxygen Species; Superoxides | 1999 |
Inhibition of peroxynitrite-mediated oxidation of dopamine by flavonoid and phenolic antioxidants and their structural relationships.
Topics: Antioxidants; Caffeic Acids; Catechin; Chromatography, High Pressure Liquid; Coumaric Acids; Dopamine; Flavonoids; Monophenol Monooxygenase; Nitrates; Oxidation-Reduction; Phenols; Propionates; Structure-Activity Relationship; Tyrosine | 1999 |
Investigation of some covalent and noncovalent complexes by matrix-assisted laser desorption/ionization time-of-flight and electrospray mass spectrometry.
Topics: Acrylamide; Amino Acid Sequence; Anilino Naphthalenesulfonates; Animals; Cattle; Cysteine; Disulfides; Lactalbumin; Lactoglobulins; Molecular Sequence Data; Nitrates; Nitrites; Peptide Fragments; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Superoxide Dismutase; Trypsin | 1999 |
Peroxynitrite-mediated modification of proteins at physiological carbon dioxide concentration: pH dependence of carbonyl formation, tyrosine nitration, and methionine oxidation.
Topics: Carbon Dioxide; Escherichia coli; Glutamate-Ammonia Ligase; Glycine max; Hydrogen-Ion Concentration; Kinetics; Lipid Peroxidation; Lipoxygenase; Methionine; Models, Chemical; Nitrates; Oxidants; Oxidation-Reduction; Serum Albumin, Bovine; Tyrosine | 1999 |
Morphine prevents peroxynitrite-induced death of human neuroblastoma SH-SY5Y cells through a direct scavenging action.
Topics: Cell Death; Drug Interactions; Humans; Morphine; Neuroblastoma; Nitrates; Nitric Oxide; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Tumor Cells, Cultured | 1999 |
The protective role of endogenous glutathione in carrageenan-induced pleurisy in the rat.
Topics: Animals; Carrageenan; Cells, Cultured; Disease Models, Animal; Free Radical Scavengers; Glutathione; Macrophages; Nitrates; Nitric Oxide; Oxidants; Pleurisy; Protective Agents; Rats; Tyrosine | 1999 |
Protective effects of a superoxide dismutase mimetic and peroxynitrite decomposition catalysts in endotoxin-induced intestinal damage.
Topics: Animals; Catalysis; Colchicine; Ferric Compounds; Free Radical Scavengers; Intestinal Mucosa; Lipid Peroxidation; Lipopolysaccharides; Male; Metalloporphyrins; Neutrophils; Nitrates; Organometallic Compounds; Oxidants; Porphyrins; Rats; Rats, Sprague-Dawley; Superoxide Dismutase; Superoxides | 1999 |
Tyrosine nitration in blood vessels occurs with increasing nitric oxide concentration.
Topics: Animals; Aorta, Thoracic; Cattle; In Vitro Techniques; Nitrates; Nitric Oxide; Nitric Oxide Donors; Nitrogen; Rabbits; Superoxides; Tyrosine | 1999 |
p130cas is a cellular target protein for tyrosine nitration induced by peroxynitrite.
Topics: Crk-Associated Substrate Protein; Humans; Molsidomine; Neuroblastoma; Nitrates; Nitric Oxide Donors; Oxidants; Phosphoproteins; Phosphorylation; Proteins; Retinoblastoma-Like Protein p130; Tumor Cells, Cultured; Tyrosine | 1999 |
Reactive oxygen species as a risk factor in verotoxin-1-exposed rats.
Topics: Animals; Aorta; Bacterial Toxins; Catalase; Cell Survival; Cells, Cultured; Drug Synergism; Endothelium, Vascular; Escherichia coli O157; Hemolytic-Uremic Syndrome; Humans; Hydroxyl Radical; Lipid Peroxidation; Lipopolysaccharides; Male; Nitrates; Nitric Oxide; Oxidoreductases; Rats; Rats, Wistar; Reactive Oxygen Species; Risk Factors; RNA, Messenger; Shiga Toxin 1; Thiobarbituric Acid Reactive Substances | 1999 |
Production of singlet oxygen by eosinophils activated in vitro by C5a and leukotriene B4.
Topics: Acridines; Animals; Complement C5a; Dihydroxydihydrobenzopyrenes; Eosinophils; Free Radical Scavengers; Guinea Pigs; Hydroxyl Radical; Leukotriene B4; Luminescent Measurements; Molecular Probes; Nitrates; Nitric Oxide; Oxygen; Singlet Oxygen; Superoxides; Tetradecanoylphorbol Acetate | 1999 |
Neuronal nitric oxide synthase activation and peroxynitrite formation in ischemic stroke linked to neural damage.
Topics: Animals; Brain; Cerebral Infarction; Citrulline; Corpus Striatum; Enzyme Activation; Functional Laterality; Immunohistochemistry; Injections, Intraperitoneal; Ischemic Attack, Transient; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Mice, Knockout; Microinjections; N-Methylaspartate; Neurons; Nitrates; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Oxidants; Tyrosine | 1999 |
Denitration of peroxynitrite-treated proteins by "protein nitratases" from dog prostate.
Topics: Animals; beta-Fructofuranosidase; Blotting, Western; Dithiothreitol; Dogs; Enzyme Activation; Glutathione Transferase; Glycoside Hydrolases; Histones; Male; Nitrates; Oxidoreductases; Polylysine; Prostate; Serum Albumin; Tissue Extracts; Tyrosine | 1999 |
No detectable NO synthesis from L-arginine or N(G)-hydroxy-L-arginine in fMLP-stimulated human blood neutrophils despite production of nitrite, nitrate, and citrulline from N(G)-hydroxy-L-arginine.
Topics: Arginine; Cells, Cultured; Citrulline; Cyclic GMP; Humans; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Nitrates; Nitric Oxide; Nitrites; Nitroarginine | 1999 |
Endothelial dysfunction in chronic myocardial infarction despite increased vascular endothelial nitric oxide synthase and soluble guanylate cyclase expression: role of enhanced vascular superoxide production.
Topics: Acetylcholine; Animals; Aorta, Thoracic; Endothelium, Vascular; Gene Expression Regulation; Guanylate Cyclase; Heart Failure; Myocardial Infarction; Nitrates; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Phenylephrine; Rats; Rats, Wistar; Renin; Superoxide Dismutase; Superoxides; Up-Regulation; Vasodilator Agents | 1999 |
Diffusion of peroxynitrite in the presence of carbon dioxide.
Topics: Biological Transport, Active; Carbon Dioxide; Diffusion; Erythrocyte Membrane; Hematocrit; Humans; In Vitro Techniques; Ion Channels; Models, Biological; Nitrates; Oxidants; Oxidation-Reduction; Oxyhemoglobins | 1999 |
Peroxynitrite modulates manganese-containing superoxide dismutase gene expression in lung epithelial cells.
Topics: Animals; Humans; Lung; Nitrates; Oxidants; Rats; Superoxide Dismutase | 1999 |
Peroxynitrite induces tryosine nitration and modulates tyrosine phosphorylation of synaptic proteins.
Topics: Animals; Brain; Brain Chemistry; Cattle; Dose-Response Relationship, Drug; Nitrates; Nitric Oxide; Oxidants; Phosphorylation; Proto-Oncogene Proteins pp60(c-src); Signal Transduction; Synapses; Synaptophysin; Synaptosomes; Tyrosine | 1999 |
Role of peroxynitrite in airway microvascular hyperpermeability during late allergic phase in guinea pigs.
Topics: Animals; Capillary Permeability; Free Radicals; Guinea Pigs; Immunoenzyme Techniques; Male; Microcirculation; Nitrates; Respiratory Hypersensitivity; Trachea; Xanthine Dehydrogenase; Xanthine Oxidase | 1999 |
Effects of reactive oxygen and nitrogen metabolites on RANTES- and IL-5-induced eosinophil chemotactic activity in vitro.
Topics: Chemokine CCL5; Chemotaxis; Deferoxamine; Dithiothreitol; Dose-Response Relationship, Drug; Eosinophils; Humans; Hydrazines; Interleukin-5; Leukotriene B4; Molsidomine; Nitrates; Nitric Oxide; Nitrogen; Pteridines; Reactive Oxygen Species; Superoxides; Tyrosine; Xanthine | 1999 |
Methamphetamine generates peroxynitrite and produces dopaminergic neurotoxicity in mice: protective effects of peroxynitrite decomposition catalyst.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Body Temperature; Corpus Striatum; Dopamine; Homovanillic Acid; Male; Methamphetamine; Mice; Mice, Inbred C57BL; Neuroprotective Agents; Neurotoxins; Nitrates; Oxidants; Porphyrins; Reference Values; Tyrosine | 1999 |
Estradiol increases rat aorta endothelium-derived relaxing factor (EDRF) activity without changes in endothelial NO synthase gene expression: possible role of decreased endothelium-derived superoxide anion production.
Topics: Animals; Aorta, Thoracic; Blotting, Western; Endothelium, Vascular; Estradiol; Female; In Vitro Techniques; Luminescent Measurements; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Superoxides | 1999 |
Cobalt prevents nitric oxide-induced apoptotic motoneuron death in vitro.
Topics: Adenosine Triphosphate; Animals; Apoptosis; Calcium; Cells, Cultured; Cobalt; Cyclic GMP; Electrophysiology; Motor Neurons; Nerve Degeneration; Nitrates; Nitric Oxide; Nitric Oxide Donors; Nitroso Compounds; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerases; Proteins; Rats | 1999 |
Chlorination and nitration of soy isoflavones.
Topics: Chromatography, High Pressure Liquid; Genistein; Glycine max; Hypochlorous Acid; Isoflavones; Magnetic Resonance Spectroscopy; Mass Spectrometry; Nitrates | 1999 |
Radical mechanisms of the decomposition of peroxynitrite and the peroxynitrite-CO(2) adduct and of reactions with L-tyrosine and related compounds as studied by (15)N chemically induced dynamic nuclear polarization.
Topics: Carbon Dioxide; Free Radicals; Magnetic Resonance Spectroscopy; Nitrates; Tyrosine | 1999 |
The survival of skeletal muscle myoblasts in vitro is sensitive to a donor of nitric oxide and superoxide, SIN-1, but not to nitric oxide or peroxynitrite alone.
Topics: Animals; Cell Line; Cell Survival; Molsidomine; Muscle, Skeletal; Nitrates; Nitric Oxide; Nitric Oxide Donors; Nitroso Compounds; Oxyhemoglobins; Rats; Superoxide Dismutase; Superoxides; Uric Acid; Xanthine Oxidase | 1999 |
Peroxynitrite induces contractile dysfunction and lipid peroxidation in the diaphragm.
Topics: Aldehydes; Animals; Calcium; Diaphragm; Kinetics; Lipid Peroxidation; Molsidomine; Muscle Contraction; Nitrates; Nitric Oxide Donors; Rats; Thiobarbituric Acid Reactive Substances | 1999 |
Activation of src tyrosine kinases by peroxynitrite.
Topics: Animals; Carbon Dioxide; Cattle; Enzyme Activation; Enzyme Precursors; Erythrocytes; Humans; Intracellular Signaling Peptides and Proteins; Nitrates; Oncogene Proteins, Viral; Phosphorylation; Precipitin Tests; Protein-Tyrosine Kinases; Proteins; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-fyn; Proto-Oncogene Proteins c-hck; Signal Transduction; src-Family Kinases; Syk Kinase; Synaptosomes; Up-Regulation | 1999 |
Superoxide dismutase and hydrogen peroxide cause rapid nitric oxide breakdown, peroxynitrite production and subsequent cell death.
Topics: Animals; Cell Death; Cell Line; Electrochemistry; Hydrogen Peroxide; Macrophages; Mice; Mitochondria, Liver; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Rhodamine 123; Rhodamines; Spectrometry, Fluorescence; Superoxide Dismutase | 1999 |
Antioxidant activity: what do we measure?
Topics: Amidines; Antioxidants; Benzothiazoles; Nitrates; Oxidants; Oxidation-Reduction; Sulfonic Acids | 1999 |
Reaction of peroxynitrite with reduced nicotinamide nucleotides, the formation of hydrogen peroxide.
Topics: Free Radical Scavengers; Free Radicals; Glutathione; Hydrogen Peroxide; Molsidomine; NAD; NADP; Nitrates; Superoxides | 1999 |
Endogenous peroxynitrite mediates mitochondrial dysfunction in rat diaphragm during endotoxemia.
Topics: Animals; Diaphragm; Endotoxemia; Escherichia coli; Hydrogen Peroxide; Kinetics; Lipopolysaccharides; Male; Mitochondria, Muscle; Muscle Contraction; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; omega-N-Methylarginine; Oxygen Consumption; Rats; Rats, Sprague-Dawley; Superoxide Dismutase; Superoxides | 1999 |
Protective effects of poly (ADP-ribose) synthase inhibitors in zymosan-activated plasma induced paw edema.
Topics: Animals; Benzamides; Complement Activation; Dose-Response Relationship, Drug; Edema; Enzyme Inhibitors; Free Radicals; Immunohistochemistry; Inflammation; Male; Niacinamide; Nitrates; Peroxidase; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Rats; Rats, Wistar; Tyrosine; Zymosan | 1999 |
Effect of reactive oxygen metabolites on endothelial permeability: role of nitric oxide and iron.
Topics: Animals; Capillary Permeability; Catalase; Cattle; Cells, Cultured; Endothelium, Vascular; Enzyme Inhibitors; Hydrogen Peroxide; Iron; Kinetics; Nitrates; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitrogen Oxides; Reactive Oxygen Species; Spermine; Superoxide Dismutase; Superoxides; Xanthine; Xanthine Oxidase | 1999 |
Persistent oxidative stress in human colorectal carcinoma, but not in adenoma.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Adenocarcinoma; Adenoma; Adult; Aged; Aldehydes; Case-Control Studies; Chromatography, High Pressure Liquid; Colorectal Neoplasms; Deoxyguanosine; Epithelial Cells; Female; Humans; Immunohistochemistry; Male; Middle Aged; Nitrates; Oxidants; Oxidative Stress; Reactive Oxygen Species; Time Factors | 1999 |
In vitro effects of peroxynitrite on human spermatozoa.
Topics: Humans; In Vitro Techniques; Lipid Peroxidation; Male; Malondialdehyde; Nitrates; Nitric Oxide; Reactive Oxygen Species; Sperm Motility; Spermatozoa; Sulfhydryl Compounds; Superoxides | 1999 |
Protective effect of poly(ADP-ribose) synthetase inhibition on multiple organ failure after zymosan-induced peritonitis in the rat.
Topics: Animals; Benzamides; Body Weight; Disease Models, Animal; Drug Evaluation, Preclinical; Male; Multiple Organ Failure; Niacinamide; Nitrates; Peritonitis; Poly(ADP-ribose) Polymerase Inhibitors; Random Allocation; Rats; Rats, Sprague-Dawley; Time Factors; Zymosan | 1999 |
Protective effect of N-acetylcysteine on multiple organ failure induced by zymosan in the rat.
Topics: Acetylcysteine; Animals; Body Weight; Disease Models, Animal; Drug Evaluation, Preclinical; Free Radical Scavengers; Leukocyte Count; Male; Multiple Organ Failure; Nitrates; Nitric Oxide; Peritonitis; Random Allocation; Rats; Rats, Sprague-Dawley; Shock, Septic; Survival Analysis; Time Factors; Zymosan | 1999 |
Effects of exogenous nitric oxide and hyperoxia on lung fibroblast viability and DNA fragmentation.
Topics: Antioxidants; Catalase; Cell Survival; Cells, Cultured; DNA Fragmentation; Fibroblasts; Humans; Hyperoxia; In Situ Nick-End Labeling; Lung; Nitrates; Nitric Oxide; Oxygen; Superoxides; Tyrosine | 1999 |
Formation and loss of nitrated proteins in peroxynitrite-treated rat skin in vivo.
Topics: Animals; Kinetics; Male; Nitrates; Oxidants; Proteins; Rats; Rats, Wistar; Serum Albumin, Bovine; Skin; Time Factors; Tyrosine | 1999 |
Role of peroxynitrite as a mediator of pathophysiological alterations in experimental pneumococcal meningitis.
Topics: Animals; Blood-Brain Barrier; Brain; Cerebrospinal Fluid; Free Radical Scavengers; Inflammation; Intracranial Pressure; Leukocytes; Male; Meningitis, Pneumococcal; Nitrates; Oxidants; Rats; Rats, Wistar; Subarachnoid Space; Tyrosine; Uric Acid | 1999 |
Inhibition of guanylate cyclase stimulation by NO and bovine arterial relaxation to peroxynitrite and H2O2.
Topics: Animals; Cattle; Coronary Vessels; Guanylate Cyclase; Hydrogen Peroxide; Muscle Contraction; Muscle, Smooth, Vascular; Nitrates; Nitric Oxide; Oxidants; Pulmonary Artery | 1999 |
Effects of reactive oxygen and nitrogen metabolites on MCP-1-induced monocyte chemotactic activity in vitro.
Topics: Blood Physiological Phenomena; Cells, Cultured; Chemokine CCL2; Chemotaxis, Leukocyte; Dose-Response Relationship, Drug; Humans; Leukotriene B4; Monocytes; Nitrates; Nitrogen; Oxidants; Reactive Oxygen Species; Reducing Agents; Superoxides; Tyrosine | 1999 |
Rapid and irreversible inactivation of protein tyrosine phosphatases PTP1B, CD45, and LAR by peroxynitrite.
Topics: Aniline Compounds; Anions; Dithiothreitol; Dose-Response Relationship, Drug; Enzyme Inhibitors; Glutathione; Humans; Leukocyte Common Antigens; Models, Molecular; Molsidomine; Nitrates; Nitric Oxide; Nitroso Compounds; Organophosphates; Organophosphorus Compounds; Protein Tyrosine Phosphatases; Receptor-Like Protein Tyrosine Phosphatases, Class 4; Receptors, Cell Surface; S-Nitrosoglutathione; Superoxide Dismutase; Tyrosine | 1999 |
Bcl-2 facilitates recovery from DNA damage after oxidative stress.
Topics: Animals; Apoptosis; Clusterin; Complement Inactivator Proteins; DNA Damage; DNA Repair; DNA, Mitochondrial; DNA, Single-Stranded; Glycoproteins; Hydrogen Peroxide; Molecular Chaperones; Neurons; Nitrates; Nitric Oxide Donors; Nitroprusside; Oxidants; Oxidative Stress; PC12 Cells; Proto-Oncogene Proteins c-bcl-2; Rats; Sulfhydryl Reagents; Transfection | 1999 |
Formation of guanidinosuccinic acid, a stable nitric oxide mimic, from argininosuccinic acid and nitric oxide-derived free radicals.
Topics: Argininosuccinic Acid; Benzoates; Chromatography, High Pressure Liquid; Dimethyl Sulfoxide; Feedback; Free Radical Scavengers; Free Radicals; Guanidines; Hydrazines; Hydroxyl Radical; Imidazoles; Molsidomine; Nitrates; Nitric Oxide; Nitric Oxide Donors; Reactive Oxygen Species; Receptors, N-Methyl-D-Aspartate; Succinates; Superoxide Dismutase | 1999 |
The neuronal toxicity of sulfite plus peroxynitrite is enhanced by glutathione depletion: implications for Parkinson's disease.
Topics: Animals; Cell Line; Cell Survival; Glutathione; Neurons; Nitrates; Parkinson Disease; Rats; Substantia Nigra; Sulfites; Tetrazolium Salts; Time Factors | 1999 |
Vascular peroxynitrite formation during organic nitrate tolerance.
Topics: Animals; Aorta, Thoracic; Blood Proteins; Drug Tolerance; Immunohistochemistry; Male; Nitrates; Nitroglycerin; Rats; Rats, Sprague-Dawley; Tyrosine; Vasodilator Agents | 1999 |
Mitogen-activated protein kinase pathway mediates peroxynitrite-induced apoptosis in human dopaminergic neuroblastoma SH-SY5Y cells.
Topics: Antioxidants; Apoptosis; Calcium-Calmodulin-Dependent Protein Kinases; Caspase 3; Caspase Inhibitors; Caspases; DNA Fragmentation; Dopamine; Enzyme Activation; Flavonoids; Humans; Imidazoles; Mitogen-Activated Protein Kinases; Molsidomine; Neuroblastoma; Neurodegenerative Diseases; Neurons; Nitrates; Nitric Oxide; p38 Mitogen-Activated Protein Kinases; Pyridines; Signal Transduction; Superoxides; Tumor Cells, Cultured | 1999 |
Peroxynitrite modification of protein thiols: oxidation, nitrosylation, and S-glutathiolation of functionally important cysteine residue(s) in the sarcoplasmic reticulum Ca-ATPase.
Topics: Acetamides; Animals; Calcium-Transporting ATPases; Chromatography, High Pressure Liquid; Cysteine; Dose-Response Relationship, Drug; Fluoroacetates; Gas Chromatography-Mass Spectrometry; Glutathione; Indicators and Reagents; Mass Spectrometry; Nitrates; Nitric Oxide; Oxidation-Reduction; p-Dimethylaminoazobenzene; Peptide Fragments; Rabbits; Sarcoplasmic Reticulum; Sulfhydryl Compounds; Trifluoroacetic Acid | 1999 |
Regulation of prostaglandin H2 synthase activity by nitrogen oxides.
Topics: Animals; Aorta, Thoracic; Arteriosclerosis; Cells, Cultured; Cyclooxygenase 1; Enzyme Activation; Enzyme Inhibitors; Free Radical Scavengers; Hydrazines; Isoenzymes; Male; Membrane Proteins; Molsidomine; Muscle, Smooth, Vascular; Nitrates; Nitric Oxide; Nitric Oxide Donors; Nitrogen Oxides; Penicillamine; Peroxides; Prostaglandin Antagonists; Prostaglandin-Endoperoxide Synthases; Rats; S-Nitroso-N-Acetylpenicillamine; Sheep; Superoxides | 1999 |
Melatonin inhibits the vasorelaxant action of peroxynitrite in human umbilical artery.
Topics: Antioxidants; Female; Free Radical Scavengers; Humans; In Vitro Techniques; Melatonin; Molsidomine; Nitrates; Nitric Oxide Donors; Pre-Eclampsia; Pregnancy; Umbilical Arteries; Vasodilation | 1999 |
IL-6 knock-out mice exhibit resistance to splanchnic artery occlusion shock.
Topics: Animals; Antibodies, Monoclonal; Arterial Occlusive Diseases; Celiac Artery; Constriction; Cytokines; Ileum; Immunity, Innate; Intercellular Adhesion Molecule-1; Interleukin-6; Ischemia; Leukocyte Count; Lipid Peroxidation; Malondialdehyde; Mesenteric Artery, Superior; Mice; Mice, Knockout; Neutrophils; Nitrates; Nitric Oxide; P-Selectin; Peroxidase; Reperfusion Injury; Shock; Splanchnic Circulation; Tyrosine | 1999 |
Requirement of intracellular calcium mobilization for peroxynitrite-induced poly(ADP-ribose) synthetase activation and cytotoxicity.
Topics: Animals; Biological Transport; Calcium; Caspase 3; Caspases; Cell Division; Chelating Agents; DNA Damage; DNA Fragmentation; Drug Interactions; Egtazic Acid; Enzyme Activation; Female; In Vitro Techniques; Male; Mice; Mitochondria; Nitrates; Oxidants; Phosphatidylserines; Poly(ADP-ribose) Polymerases; Thymus Gland | 1999 |
Distinct roles of peroxynitrite and hydroxyl radical in triggering stunned myocardium-like impairment of cardiac myocytes in vitro.
Topics: Adenosine Triphosphate; Animals; Calcium; Cell Membrane Permeability; Cell Movement; Heart; Hydrogen-Ion Concentration; Hydroxyl Radical; Mice; Mice, Inbred ICR; Nitrates; Sulfhydryl Compounds | 1999 |
Peroxynitrite mediated damage and lowered superoxide tolerance in primary cortical glial cultures after induction of the inducible isoform of NOS.
Topics: Animals; Animals, Newborn; Blotting, Western; Cell Survival; Cells, Cultured; Cerebral Cortex; Citrate (si)-Synthase; Enzyme Induction; L-Lactate Dehydrogenase; Nerve Tissue Proteins; Neuroglia; Nitrates; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; Oxidants; Paraquat; Rats; Rats, Wistar; Superoxides; Xanthine Oxidase | 1999 |
Peroxynitrite anion stimulates arginine release from cultured rat astrocytes.
Topics: Animals; Animals, Newborn; Arginine; Astrocytes; Cells, Cultured; Citrulline; Glutamic Acid; Hydrogen Peroxide; Kinetics; Lysine; Nitrates; Nitric Oxide Donors; Oxidants; Rats; Rats, Wistar; Serine | 1999 |
Dose dependency of L-arginine in neonatal myocardial protection: the nitric oxide paradox.
Topics: Animals; Animals, Newborn; Arginine; Blood; Blood Pressure; Cardiac Volume; Cardioplegic Solutions; Cardiopulmonary Bypass; Coronary Vessels; Diastole; Dose-Response Relationship, Drug; Free Radical Scavengers; Heart; Hypoxia; Leukocytes; Nitrates; Nitric Oxide; Oxidants; Peroxidase; Stress, Physiological; Stroke Volume; Swine; Systole; Vascular Resistance; Vasodilator Agents | 1999 |
L-arginine, prostaglandin, and white cell filtration equally improve myocardial protection in stressed neonatal hearts.
Topics: Alprostadil; Animals; Animals, Newborn; Arginine; Blood Pressure; Cardiac Volume; Cardioplegic Solutions; Cardiopulmonary Bypass; Coronary Vessels; Diastole; Free Radicals; Heart; Hypoxia; Leukapheresis; Leukocytes; Nitrates; Nitric Oxide; Oxidants; Peroxidase; Stress, Physiological; Stroke Volume; Swine; Systole; Vascular Resistance; Vasodilator Agents | 1999 |
In situ methods for detection and localization of markers of oxidative stress: application in neurodegenerative disorders.
Topics: Aldehydes; Alzheimer Disease; Analysis of Variance; Biomarkers; DNA Damage; Glycation End Products, Advanced; Heme Oxygenase (Decyclizing); Heme Oxygenase-1; Histocytochemistry; Humans; Iron; Membrane Proteins; Neurodegenerative Diseases; Neurofibrillary Tangles; Neurons; Nitrates; Oxidation-Reduction; Oxidative Stress; Oxygen; Phenylhydrazines; Plaque, Amyloid; Tyrosine | 1999 |
Effects of a novel guanylyl cyclase inhibitor on the vascular actions of nitric oxide and peroxynitrite in immunostimulated smooth muscle cells and in endotoxic shock.
Topics: Animals; Aorta; Cell Respiration; Cells, Cultured; Enzyme Inhibitors; Guanylate Cyclase; In Vitro Techniques; Interferon-gamma; Lipopolysaccharides; Male; Mice; Mitochondria; Muscle, Smooth, Vascular; Nitrates; Nitric Oxide; Nitrites; Oxadiazoles; Oxidants; Quinoxalines; Rats; Rats, Wistar; Shock, Septic; Survival Analysis; Vasodilation | 1999 |
Oxidative damage to proteins of bronchoalveolar lavage fluid in patients with acute respiratory distress syndrome: evidence for neutrophil-mediated hydroxylation, nitration, and chlorination.
Topics: Adolescent; Adult; Aged; Biomarkers; Bronchoalveolar Lavage Fluid; Case-Control Studies; Chromatography, High Pressure Liquid; Female; Humans; Hydroxyl Radical; Hydroxylation; Hypochlorous Acid; Linear Models; Male; Middle Aged; Neutrophil Activation; Neutrophils; Nitrates; Oxidants; Oxidative Stress; Proteins; Respiration, Artificial; Respiratory Distress Syndrome; Statistics, Nonparametric; Tyrosine | 1999 |
Inhibitory mechanism of sinapinic acid against peroxynitrite-mediated tyrosine nitration of protein in vitro.
Topics: Chromatography, High Pressure Liquid; Coumaric Acids; Dimerization; Magnetic Resonance Spectroscopy; Mass Spectrometry; Nitrates; Oxidation-Reduction; Proteins; Tyrosine | 1999 |
Oxidation of tetrahydrobiopterin by peroxynitrite: implications for vascular endothelial function.
Topics: Antioxidants; Biopterins; Endothelium, Vascular; Kinetics; Nitrates; Nitric Oxide Synthase; Oxidants; Oxidation-Reduction; Pteridines | 1999 |
Protective role of nitric oxide synthase against ischemia-reperfusion injury in guinea pig myocardial mitochondria.
Topics: Animals; Arginine; Calcium; Electron Spin Resonance Spectroscopy; Enzyme Inhibitors; Female; Free Radical Scavengers; Free Radicals; Guinea Pigs; Heart; Humans; Hydrogen Peroxide; Hydrogen-Ion Concentration; Immunoblotting; Immunohistochemistry; Male; Mitochondria, Heart; Myocardial Reperfusion Injury; Myocardium; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Penicillamine; Reactive Oxygen Species; Spin Trapping; Superoxide Dismutase | 1999 |
Peroxynitrite inactivates tryptophan hydroxylase via sulfhydryl oxidation. Coincident nitration of enzyme tyrosyl residues has minimal impact on catalytic activity.
Topics: Catalysis; Kinetics; Nitrates; Sulfhydryl Compounds; Tetranitromethane; Tryptophan Hydroxylase | 1999 |
Generation of reactive oxygen intermediates, activation of NF-kappaB, and induction of apoptosis in human endothelial cells by glucose: role of nitric oxide synthase?
Topics: 3-O-Methylglucose; Antioxidants; Apoptosis; Binding Sites; Cells, Cultured; DNA Fragmentation; DNA-Binding Proteins; Endothelium, Vascular; Fluorescent Dyes; Glucose; Humans; Microscopy, Fluorescence; NF-kappa B; Nitrates; Nitroarginine; Oligodeoxyribonucleotides, Antisense; Reactive Oxygen Species | 1999 |
Increased expression of inducible nitric oxide synthase and peroxynitrite in Helicobacter pylori gastric ulcer.
Topics: Fluorescent Antibody Technique; Gastric Mucosa; Gastritis; Helicobacter pylori; Humans; Macrophages; Nitrates; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Peptic Ulcer; Tyrosine | 1999 |
Effects of reactive oxygen species on brain synaptic plasma membrane Ca(2+)-ATPase.
Topics: Age Factors; Amidines; Animals; Azo Compounds; Brain; Calcium; Calcium-Transporting ATPases; Hydrogen Peroxide; Kinetics; Male; Nitrates; Oxidative Stress; Phenylhydrazines; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Synaptic Membranes; Tyrosine; Urea; Valerates | 1999 |
Evidence for a feedback inhibition of NO synthesis in enteric synaptosomes via a nitrosothiol intermediate.
Topics: Animals; Feedback; Free Radical Scavengers; Glutathione; Ileum; Male; Muscle Relaxation; Muscle, Smooth; Nitrates; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitroso Compounds; Rats; Rats, Wistar; Subcellular Fractions; Sulfhydryl Compounds; Superoxide Dismutase; Superoxides; Synaptosomes | 1999 |
Evidence for peroxynitrite as a signaling molecule in flow-dependent activation of c-Jun NH(2)-terminal kinase.
Topics: Animals; Blood Circulation; Cattle; Cells, Cultured; Enzyme Activation; JNK Mitogen-Activated Protein Kinases; Mitogen-Activated Protein Kinases; Nitrates; Nitric Oxide; Signal Transduction; Superoxides; Tyrosine | 1999 |
Nitration of angiotensin II by .NO2 radicals and peroxynitrite. .NO protects against .NO2 radical reaction.
Topics: Angiotensin II; Chromatography, High Pressure Liquid; Free Radicals; Humans; In Vitro Techniques; Mass Spectrometry; Nitrates; Nitric Oxide; Nitrogen Dioxide | 1999 |
Oxidation of acetaldehyde by peroxynitrite and hydrogen Peroxide/Iron(II). Production Of acetate, formate, and methyl radicals.
Topics: Acetaldehyde; Acetates; Electron Spin Resonance Spectroscopy; Electrophoresis, Capillary; Formates; Free Radicals; Hydrogen Peroxide; Hydrogen-Ion Concentration; Iron; Kinetics; Methylation; Nitrates; Oxidants; Oxidation-Reduction | 1999 |
Failure of selenomethionine residues in albumin and immunoglobulin G to protect against peroxynitrite.
Topics: Adult; Humans; Immunoglobulin G; Male; Nitrates; Oxidants; Oxidation-Reduction; Selenium; Selenomethionine; Serum Albumin | 1999 |
Manganese and iron porphyrins catalyze peroxynitrite decomposition and simultaneously increase nitration and oxidant yield: implications for their use as peroxynitrite scavengers in vivo.
Topics: Ascorbic Acid; Catalysis; Free Radical Scavengers; Iron; Kinetics; Manganese; Metalloporphyrins; Models, Chemical; Molecular Conformation; Molecular Structure; Nitrates; Oxidants | 1999 |
Role of IL-6 in the pleurisy and lung injury caused by carrageenan.
Topics: Animals; Carrageenan; Cells, Cultured; Cytokines; Dinoprostone; DNA Damage; Enzyme Induction; Interleukin-6; Leukotriene B4; Lung; Macrophages; Male; Malondialdehyde; Mice; Mice, Knockout; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Peroxidase; Pleura; Pleurisy; Poly(ADP-ribose) Polymerases; Prostaglandin-Endoperoxide Synthases; Prostaglandins F; Tyrosine | 1999 |
Mitochondrial nitric-oxide synthase stimulation causes cytochrome c release from isolated mitochondria. Evidence for intramitochondrial peroxynitrite formation.
Topics: Animals; Apoptosis; Calcium; Cyclosporine; Cytochrome c Group; Enzyme Activation; Ion Channels; Lipid Peroxidation; Membrane Potentials; Membrane Proteins; Mitochondria, Liver; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Nitrates; Nitric Oxide Synthase; Oxidants; Oxygen Consumption; Proto-Oncogene Proteins c-bcl-2; Rats; Ruthenium Red | 1999 |
Cytokine-mediated apoptosis in cardiac myocytes: the role of inducible nitric oxide synthase induction and peroxynitrite generation.
Topics: Animals; Apoptosis; Cells, Cultured; Cytokines; Enzyme Induction; Heart; Myocardium; Nitrates; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Rats; Rats, Sprague-Dawley; Signal Transduction | 1999 |
Parsing the effects of nitric oxide, S-nitrosothiols, and peroxynitrite on inducible nitric oxide synthase-dependent cardiac myocyte apoptosis.
Topics: Apoptosis; Humans; Mercaptoethanol; Myocardium; Nitrates; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitroso Compounds; S-Nitrosothiols; Up-Regulation | 1999 |
Modification of proteins and polynucleotides by peroxynitrite.
Topics: Animals; Nitrates; Nitric Oxide; Oxidants; Proteins; Rabbits; Tyrosine | 1999 |
Role of superoxide anion in the pathogenesis of cytokine-induced myocardial dysfunction in dogs in vivo.
Topics: Analysis of Variance; Animals; Antioxidants; Biomarkers; Dogs; Echocardiography; Female; Interleukin-1; Male; Myocardium; Nitrates; Random Allocation; Stroke Volume; Superoxides; Thiazoles; Tyrosine; Ventricular Dysfunction, Left | 1999 |
Reduced antilisterial activity of TNF-deficient bone marrow-derived macrophages is due to impaired superoxide production.
Topics: Animals; Bone Marrow Cells; Free Radical Scavengers; Immunologic Deficiency Syndromes; Listeria monocytogenes; Macrophages; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Nitrates; Nitric Oxide; Oxidants; Superoxides; Tumor Necrosis Factor-alpha | 1999 |
The protective role of endogenous melatonin in carrageenan-induced pleurisy in the rat.
Topics: Animals; Carrageenan; Cells, Cultured; Energy Metabolism; Lipid Peroxidation; Macrophages; Melatonin; Nitrates; Nitric Oxide; Peroxidase; Pleurisy; Rats; Tyrosine | 1999 |
Factors determining the selectivity of protein tyrosine nitration.
Topics: Amino Acid Sequence; Models, Molecular; Molecular Sequence Data; Muramidase; Nitrates; Nitric Oxide; Phospholipases A; Protein Processing, Post-Translational; Protein Structure, Secondary; Ribonuclease, Pancreatic; Sequence Analysis, Protein; Superoxides; Tyrosine | 1999 |
[Redox sensitive behavior of selenite in the presence of reactive oxygen species. Are there nonenzymatic direct reaction pathways].
Topics: Arteriosclerosis; Humans; Lipid Peroxidation; Magnetic Resonance Spectroscopy; Nitrates; Oxidation-Reduction; Reactive Oxygen Species; Respiratory Burst; Selenium | 1999 |
Endothelium-dependent relaxation of rabbit atherosclerotic aorta was not restored by control of hyperlipidemia: the possible role of peroxynitrite (ONOO(-)).
Topics: Acetylcholine; Animals; Arteriosclerosis; Chromatography, High Pressure Liquid; Culture Techniques; Diet, Atherogenic; Endothelium, Vascular; Hyperlipidemias; Immunohistochemistry; Male; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Oxidants; Rabbits; Reference Values; Reproducibility of Results; Vasodilation | 1999 |
Immunohistochemical nitrotyrosine distribution in neonatal rat cerebrocortical slices during and after hypoxia.
Topics: Animals; Brain; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Hypoxia-Ischemia, Brain; N-Methylaspartate; Neurons; Nitrates; Nitric Oxide; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Superoxides; Tyrosine | 1999 |
Role of melatonin in reduction of lipid peroxidation and peroxynitrite formation in non-septic shock induced by zymosan.
Topics: Animals; Antioxidants; Disease Models, Animal; Exudates and Transudates; Immunohistochemistry; Kidney; Lipid Peroxidation; Liver; Lung; Male; Malondialdehyde; Melatonin; Nitrates; Rats; Rats, Sprague-Dawley; Shock; Tyrosine; Zymosan | 1999 |
Protection against oxidative damage and cell death by the natural antioxidant ergothioneine.
Topics: Animals; Antioxidants; Cattle; Cell Death; Cell Line; Cell Survival; DNA; DNA Damage; Ergothioneine; Humans; Hybridomas; Hydrogen Peroxide; Mice; Neurons; Nitrates; Oxidation-Reduction; Oxidative Stress; Rats | 1999 |
Peroxynitrite, the breakdown product of nitric oxide, is beneficial in blood cardioplegia but injurious in crystalloid cardioplegia.
Topics: Animals; Cardiopulmonary Bypass; Dogs; Heart Arrest, Induced; Myocardial Reperfusion Injury; Nitrates; Nitric Oxide; Oxidants | 1999 |
Formation of peroxynitrite during thiol-mediated reduction of sodium nitroprusside.
Topics: Dithiothreitol; Edetic Acid; Nitrates; Nitroprusside; Oxidation-Reduction; Pentetic Acid | 1999 |
Sensitivity of antioxidant-deficient yeast Saccharomyces cerevisiae to peroxynitrite and nitric oxide.
Topics: Antioxidants; Nitrates; Nitric Oxide; Saccharomyces cerevisiae | 1999 |
Modulation of lung reperfusion injury by nitric oxide: impact of inspired oxygen fraction.
Topics: Administration, Inhalation; Animals; Capillary Permeability; Lung; Male; Nitrates; Nitric Oxide; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Vascular Resistance | 1999 |
Mass spectrometric quantification of 3-nitrotyrosine, ortho-tyrosine, and o,o'-dityrosine in brain tissue of 1-methyl-4-phenyl-1,2,3, 6-tetrahydropyridine-treated mice, a model of oxidative stress in Parkinson's disease.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Amino Acids; Animals; Brain; Chelating Agents; Dopamine Agents; Free Radicals; Gas Chromatography-Mass Spectrometry; Male; Mice; Mice, Inbred C57BL; Nitrates; Oxidation-Reduction; Oxidative Stress; Parkinson Disease; Pentetic Acid; Tissue Distribution; Tyrosine | 1999 |
Peroxynitrite inactivation of tyrosine hydroxylase: mediation by sulfhydryl oxidation, not tyrosine nitration.
Topics: Bicarbonates; Enzyme Activation; Nitrates; Oxidants; Oxidation-Reduction; Pyrimidines; Pyrroles; Sulfhydryl Compounds; Tetranitromethane; Tyrosine; Tyrosine 3-Monooxygenase | 1999 |
Beneficial effects of Mn(III)tetrakis (4-benzoic acid) porphyrin (MnTBAP), a superoxide dismutase mimetic, in zymosan-induced shock.
Topics: Alanine Transaminase; Alkaline Phosphatase; Animals; Bilirubin; Disease Models, Animal; DNA Damage; Dose-Response Relationship, Drug; Energy Metabolism; Free Radical Scavengers; Immunohistochemistry; L-Lactate Dehydrogenase; Lung; Male; Malondialdehyde; Metalloporphyrins; NAD; Nitrates; Peroxidase; Rats; Rats, Sprague-Dawley; Shock; Superoxide Dismutase; Tyrosine; Zymosan | 1999 |
Protection against peroxynitrite by cocoa polyphenol oligomers.
Topics: Biflavonoids; Cacao; Catechin; Flavonoids; Nitrates; Oxidants; Oxidation-Reduction; Phenols; Polymers; Proanthocyanidins; Protective Agents; Rhodamines; Tyrosine | 1999 |
Peroxynitrite is a positive inotropic agent in atrial and ventricular fibres of the frog heart.
Topics: Aminoquinolines; Animals; Atrial Function; Catalase; Cyclic GMP; Enzyme Inhibitors; Guanylate Cyclase; Heart Atria; Heart Ventricles; Hydroxyl Radical; Molsidomine; Muscle Fibers, Skeletal; Myocardial Contraction; Myocardium; Nitrates; Nitric Oxide Donors; Oxadiazoles; Oxidants; Quinoxalines; Rana esculenta; Sodium; Sodium-Calcium Exchanger; Ventricular Function | 1999 |
Peroxynitrite- and nitrite-induced oxidation of dopamine: implications for nitric oxide in dopaminergic cell loss.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Alcohol Dehydrogenase; Antioxidants; Apoptosis; Catalase; Chromatography, High Pressure Liquid; Dopamine; Hydrogen-Ion Concentration; Methamphetamine; Monophenol Monooxygenase; Nerve Tissue Proteins; Neurons; Nitrates; Nitric Oxide; Nitrites; Oxidants; Oxidation-Reduction; Parkinson Disease; Protein Binding; Sulfhydryl Compounds; Superoxide Dismutase | 1999 |
[Merits and demerits of nitric oxide].
Topics: Apoptosis; Cell Division; Cyclic GMP; Free Radical Scavengers; Humans; Neoplasms; Nitrates; Nitric Oxide; Superoxides; Vasodilation | 1999 |
The peroxynitrite reductase activity of cytochrome c oxidase involves a two-electron redox reaction at the heme a(3)-Cu(B) site.
Topics: Animals; Carbon Monoxide; Cattle; Copper; Electron Transport; Electron Transport Complex IV; Heme; Kinetics; Mitochondria, Heart; Nitrates; Oxidants; Oxidation-Reduction; Oxidoreductases; Spectrophotometry | 1999 |
Uric acid oxidation by peroxynitrite: multiple reactions, free radical formation, and amplification of lipid oxidation.
Topics: Allantoin; Alloxan; Cyclic N-Oxides; Electron Spin Resonance Spectroscopy; Free Radical Scavengers; Free Radicals; Horseradish Peroxidase; Humans; Hydrogen Peroxide; Hydrogen-Ion Concentration; Kinetics; Lipid Metabolism; Lipid Peroxides; Lipoproteins, LDL; Liposomes; Nitrates; Nitrous Acid; Oxidants; Oxidation-Reduction; Oxygen; Peroxynitrous Acid; Thiobarbituric Acid Reactive Substances; Uric Acid | 1999 |
Mechanistic studies of the oxidation of pyridoxalated hemoglobin polyoxyethylene conjugate by nitrogen monoxide.
Topics: Blood Substitutes; Free Radical Scavengers; Half-Life; Hemoglobins; Hydrogen-Ion Concentration; Kinetics; Methemoglobin; Nitrates; Nitric Oxide; Oxidants; Oxidation-Reduction; Oxyhemoglobins; Polyethylene Glycols | 1999 |
NOX, a novel nitric oxide scavenger, reduces bacterial translocation in rats after endotoxin challenge.
Topics: Animals; Bacteremia; Enterobacteriaceae; Enterocytes; Free Radical Scavengers; Infusion Pumps, Implantable; Intestinal Absorption; Intestines; Lipopolysaccharides; Male; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Organometallic Compounds; Rats; Rats, Sprague-Dawley; Thiocarbamates; Tyrosine | 1999 |
Mercaptoethylguanidine inhibits the inflammatory response in a murine model of chronic infection with Pseudomonas aeruginosa.
Topics: Anesthesia; Animals; Biomarkers; Body Weight; Cytokines; Enzyme Inhibitors; Female; Guanidines; Inflammation; Intubation, Intratracheal; Mice; Neutrophil Infiltration; Nitrates; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Oxidants; Peroxidase; Pneumonia, Bacterial; Pseudomonas Infections; Time Factors | 2000 |
The beneficial effects of peroxynitrite on ischaemia-reperfusion arrhythmias in rat isolated hearts.
Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Catalase; Dose-Response Relationship, Drug; Heart; Heart Rate; Heart Ventricles; In Vitro Techniques; Male; NG-Nitroarginine Methyl Ester; Nitrates; Rats; Reperfusion Injury; Superoxide Dismutase; Uric Acid; Ventricular Fibrillation | 1999 |
Effects of reactive oxygen and nitrogen metabolites on eotaxin-induced eosinophil chemotactic activity in vitro.
Topics: Binding Sites; Chemokine CCL11; Chemokines, CC; Chemotactic Factors, Eosinophil; Chemotaxis, Leukocyte; Cytokines; Eosinophils; Humans; Hydrazines; Nitrates; Nitric Oxide; Nitrogen; Reactive Oxygen Species; Reducing Agents; Superoxides; Xanthine; Xanthine Oxidase | 2000 |
Induction of nitric oxide-dependent apoptosis in motor neurons by zinc-deficient superoxide dismutase.
Topics: Amyotrophic Lateral Sclerosis; Animals; Apoptosis; Brain-Derived Neurotrophic Factor; Cells, Cultured; Chelating Agents; Copper; Fluoresceins; Liposomes; Motor Neurons; Mutation; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Oxidation-Reduction; Rats; Superoxide Dismutase; Superoxides; Zinc | 1999 |
Interaction of peroxynitrite with carotenoids in human low density lipoproteins.
Topics: Arteriosclerosis; beta Carotene; Carotenoids; Cryptoxanthins; Fluorescent Dyes; Free Radical Scavengers; Humans; In Vitro Techniques; Lipoproteins, LDL; Lutein; Lycopene; Nitrates; Rhodamine 123; Spectrometry, Fluorescence; Xanthophylls; Zeaxanthins | 2000 |
Peroxynitrite-mediated oxidation of fibrinogen inhibits clot formation.
Topics: Bilirubin; Blood Coagulation; Carbon Dioxide; Dose-Response Relationship, Drug; Fibrinogen; Humans; Nitrates; Oxidation-Reduction; Thrombin; Time Factors | 1999 |
Ghost protein damage by peroxynitrite and its protection by melatonin.
Topics: Animals; Antioxidants; Cytoskeletal Proteins; Electrophoresis, Polyacrylamide Gel; Erythrocyte Membrane; Free Radical Scavengers; Melatonin; Mice; Nitrates; Oxidants; Oxidative Stress; Spectrin | 2000 |
Enhancement by glucose of low density lipoprotein-oxidation by peroxynitrite.
Topics: Glucose; Humans; Kinetics; Lipoproteins, LDL; Male; Mannitol; Middle Aged; Molsidomine; Nitrates; Nitric Oxide Donors; Oxidants; Oxidation-Reduction | 1999 |
ALS-linked Cu/Zn-SOD mutation increases vulnerability of motor neurons to excitotoxicity by a mechanism involving increased oxidative stress and perturbed calcium homeostasis.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Antioxidants; Calcium; Cells, Cultured; Cyclic N-Oxides; Estradiol; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Fluorescent Dyes; Free Radicals; Glutamic Acid; Homeostasis; Humans; Imidazoles; Lipid Peroxidation; Mice; Mice, Transgenic; Mitochondria; Motor Neuron Disease; Motor Neurons; Neurotoxins; NG-Nitroarginine Methyl Ester; Nitrates; Oxidative Stress; Rhodamine 123; Spinal Cord; Superoxide Dismutase; Superoxides; Vitamin E | 1999 |
Denitration of peroxynitrite-treated proteins by 'protein nitratases' from rat brain and heart.
Topics: Animals; beta-Fructofuranosidase; Blotting, Western; Brain; Brain Chemistry; Calcium; Dialysis; Enzymes; Flavin-Adenine Dinucleotide; Glutathione; Glutathione Transferase; Glycoside Hydrolases; Myocardium; NAD; NADP; Nitrates; Proteins; Rats; Serum Albumin, Bovine; Tissue Extracts; Tyrosine | 1999 |
Peroxynitrite diminishes gap junctional communication: protection by selenite supplementation.
Topics: Animals; Cell Communication; Cell Division; Cells, Cultured; Culture Media; Dose-Response Relationship, Drug; Epithelial Cells; Gap Junctions; Glutathione Peroxidase; Homeostasis; Liver; Nitrates; Oxidants; Protein Biosynthesis; Proteins; Rats; Rats, Inbred F344; Selenoproteins; Sodium Selenite | 1999 |
Evidence of in vivo peroxynitrite formation in patients with colorectal carcinoma, higher plasma nitrate/nitrite levels, and lower protection against oxygen free radicals.
Topics: Aged; Colorectal Neoplasms; Female; Humans; Male; Middle Aged; Nitrates; Nitrites; Oxidants; Reactive Oxygen Species | 2000 |
Administration of SIN-1 induces guinea pig airway hyperresponsiveness through inactivation of airway neutral endopeptidase.
Topics: Animals; Bronchial Hyperreactivity; Bronchoconstriction; Endothelin-1; Enzyme Activation; Glycopeptides; Guinea Pigs; Male; Molsidomine; Neprilysin; Nitrates; Oxidants; Protease Inhibitors; Respiratory System; Substance P; Trachea; Vasodilator Agents | 1999 |
Peroxynitrite irreversibly decreases diastolic and systolic function in cardiac muscle.
Topics: Animals; Diastole; Immunoenzyme Techniques; Male; Myocardial Contraction; Nitrates; Oxidants; Papillary Muscles; Rats; Systole; Tyrosine | 1999 |
Nitric oxide, superoxide, and peroxynitrite effects on the insulin secretion and viability of betaTC3 cells.
Topics: Animals; Biomedical Engineering; Cell Line; Cell Survival; Insulin; Insulin Secretion; Islets of Langerhans; Kinetics; L-Lactate Dehydrogenase; Mice; Models, Biological; Nitrates; Nitric Oxide; Superoxides | 2000 |
Peroxynitrite generated from constitutive nitric oxide synthase mediates the early biochemical injury in short-term cultured hepatocytes.
Topics: Animals; Cells, Cultured; Kinetics; Liver; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Oxidants; Oxidative Stress; Proteins; Rats; Reactive Oxygen Species | 2000 |
Water-soluble organotellurium compounds: catalytic protection against peroxynitrite and release of zinc from metallothionein.
Topics: Benzoates; Catalysis; Hydroxylation; Metallothionein; Nitrates; Nitrites; Organometallic Compounds; Oxidants; Oxidation-Reduction; Phenylacetates; Rhodamines; Solubility; Tellurium; tert-Butylhydroperoxide; Water; Zinc | 2000 |
Selenium, an antioxidant, attenuates methamphetamine-induced dopaminergic toxicity and peroxynitrite generation.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Antioxidants; Caudate Nucleus; Dopamine; Homovanillic Acid; Male; Methamphetamine; Mice; Mice, Inbred C57BL; Neurotoxins; Neurotrophin 3; Nitrates; Oxidants; PC12 Cells; Rats; Selenium; Sympathomimetics | 2000 |
Endogenous and exogenous nitric oxide enhance the DNA strand scission induced by tert-butylhydroperoxide in PC12 cells via peroxynitrite-dependent and independent mechanisms, respectively.
Topics: Animals; Calcium; Chromans; Cyclic N-Oxides; DNA Damage; DNA, Single-Stranded; Electron Transport; Free Radical Scavengers; Imidazoles; Methacrylates; Methionine; Mitochondria; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Nitric Oxide Donors; Oxidants; PC12 Cells; Penicillamine; Rats; Rotenone; Ruthenium Red; S-Nitroso-N-Acetylpenicillamine; tert-Butylhydroperoxide; Thiazoles | 2000 |
Tyrosine nitration by simultaneous generation of (.)NO and O-(2) under physiological conditions. How the radicals do the job.
Topics: Animals; Free Radicals; Humans; Nitrates; Tyrosine | 2000 |
Adaptive responses and apoptosis in endothelial cells exposed to carbon monoxide.
Topics: Adaptation, Physiological; Animals; Apoptosis; Carbon Monoxide; Caspases; Catalase; Cattle; Cells, Cultured; Endothelium, Vascular; Ethidium; Glutathione Peroxidase; Hydrogen Peroxide; Nitrates; Nitric Oxide; Oxidative Stress; Pulmonary Artery; Selenomethionine; Superoxide Dismutase; Superoxides | 2000 |
DNA damage in arsenite- and cadmium-treated bovine aortic endothelial cells.
Topics: Amitrole; Animals; Antioxidants; Aorta; Arsenites; Bacterial Proteins; Cadmium Chloride; Catalase; Cattle; Cells, Cultured; Chromans; Citrulline; Ditiocarb; DNA Damage; DNA-Formamidopyrimidine Glycosylase; Endothelium, Vascular; Enzyme Inhibitors; Escherichia coli Proteins; Free Radical Scavengers; Hydrogen Peroxide; Molsidomine; Mutagens; N-Glycosyl Hydrolases; Nitrates; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitroarginine; Onium Compounds; Phenanthrolines; Reactive Oxygen Species; Sodium Compounds; Sodium Selenite; Superoxide Dismutase; Superoxides; Thiomalates; Thiourea; Uric Acid | 2000 |
Neuroprotection by (-)-deprenyl and related compounds.
Topics: Aging; Amphetamines; Animals; Antioxidants; Apoptosis; Cattle; DNA Damage; DNA, Neoplasm; Indans; Monoamine Oxidase Inhibitors; Neuroblastoma; Neuroprotective Agents; Nitrates; Oxidants; Parkinson Disease; Selegiline; Tumor Cells, Cultured | 1999 |
Endothelial dysfunction and peroxynitrite formation are early events in angiotensin-induced cardiovascular disorders.
Topics: Acetylcholine; Angiotensin II; Animals; Aorta, Thoracic; Cardiovascular Diseases; Endothelium, Vascular; Hemodynamics; Image Processing, Computer-Assisted; Immunohistochemistry; In Vitro Techniques; Male; Nitrates; Nitroprusside; Phenylephrine; Potassium Chloride; Rats; Rats, Sprague-Dawley; Renin; Tyrosine; Vasoconstriction | 2000 |
Effect of procyanidins from Pinus maritima on glutathione levels in endothelial cells challenged by 3-morpholinosydnonimine or activated macrophages.
Topics: Animals; Biflavonoids; Catechin; Cell Line; Cells, Cultured; Endothelium, Vascular; Glutathione; Humans; Interferon-gamma; Lipopolysaccharides; Macrophage Activation; Mice; Molsidomine; Nitrates; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Plant Extracts; Proanthocyanidins; Trees | 1999 |
Cancer chemopreventive activity of majonoside-R2 from Vietnamese ginseng, Panax vietnamensis.
Topics: Alkylating Agents; Animals; Anticarcinogenic Agents; Carcinogenicity Tests; Carcinogens; Diethylnitrosamine; Female; Focal Nodular Hyperplasia; Ginsenosides; Liver Neoplasms, Experimental; Mice; Mice, Inbred ICR; Mice, Inbred SENCAR; Nitrates; Nitro Compounds; Panax; Papilloma; Phenobarbital; Plants, Medicinal; Saponins; Skin Neoplasms; Tetradecanoylphorbol Acetate; Vietnam | 1999 |
Caspase-2 mediates neuronal cell death induced by beta-amyloid.
Topics: Amyloid beta-Peptides; Animals; Apoptosis; Caspase 2; Caspase 3; Caspases; Cells, Cultured; Embryo, Mammalian; Hippocampus; Mice; Mice, Knockout; Models, Neurological; Nerve Growth Factors; Neurons; Nitrates; Oligodeoxyribonucleotides, Antisense; PC12 Cells; Peptide Fragments; Rats; Superoxide Dismutase; Sympathetic Nervous System | 2000 |
Mechanisms of peroxynitrite-induced apoptosis in HL-60 cells.
Topics: Acetylcysteine; Acridines; Apoptosis; Caspase 3; Caspases; Catalase; DNA Fragmentation; Enzyme Activation; Free Radical Scavengers; HL-60 Cells; Humans; L-Lactate Dehydrogenase; Luminescent Measurements; Nitrates; Poly(ADP-ribose) Polymerases; Reactive Oxygen Species; Signal Transduction; Superoxide Dismutase; Superoxides | 1999 |
Peroxynitrite scavengers for the acute treatment of traumatic brain injury.
Topics: Animals; Brain Injuries; Chelating Agents; Drug Evaluation, Preclinical; Male; Mice; Nitrates; Penicillamine | 1999 |
Effects of nicaraven on nitric oxide-related pathways and in shock and inflammation.
Topics: Animals; Antioxidants; Arthritis, Experimental; Carrageenan; Dose-Response Relationship, Drug; Edema; Enzyme Activation; Free Radical Scavengers; Inflammation; Interferon-gamma; Lipopolysaccharides; Macrophage Activation; Male; Mice; Mice, Inbred DBA; Niacinamide; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Oxidation-Reduction; Poly(ADP-ribose) Polymerases; Rats; Rats, Wistar; Reperfusion Injury; Shock, Hemorrhagic; Shock, Septic; Splanchnic Circulation | 2000 |
Nitrotyrosine generation via inducible nitric oxide synthase in vascular wall in focal ischemia-reperfusion.
Topics: Acidosis; Animals; Blood Glucose; Blood Pressure; Carbon Dioxide; Cerebral Cortex; Cerebrovascular Circulation; Chromatography, High Pressure Liquid; Endothelium, Vascular; Infarction, Middle Cerebral Artery; Ischemic Attack, Transient; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Oxygen; Reperfusion Injury; Tyrosine | 2000 |
Simultaneous production of nitric oxide and peroxynitrite by plant nitrate reductase: in vitro evidence for the NR-dependent formation of active nitrogen species.
Topics: Aerobiosis; Cell-Free System; Fluoresceins; Fluorescent Dyes; Glutathione; NAD; Nitrate Reductases; Nitrates; Nitric Oxide; Nitrites; Oxidants; Sodium Azide; Zea mays | 2000 |
Peroxynitrite, a two-edged sword in post-ischemic myocardial injury-dichotomy of action in crystalloid- versus blood-perfused hearts.
Topics: Animals; Cells, Cultured; Dose-Response Relationship, Drug; Endothelium, Vascular; Male; Myocardial Ischemia; Myocardial Reperfusion Injury; Neutrophils; Nitrates; Perfusion; Peroxidase; Rabbits | 2000 |
Possible mechanism of bronchoprotection by SIN-1 in anaesthetized guinea pigs: roles of nitric oxide and peroxynitrite.
Topics: Acetylcholine; Animals; Bronchi; Bronchoalveolar Lavage Fluid; Bronchoconstriction; Bronchodilator Agents; Dose-Response Relationship, Drug; Glutathione; Guinea Pigs; Male; Molsidomine; Nebulizers and Vaporizers; Nitrates; Nitric Oxide; Penicillamine; Rhodamines; Time Factors; Vasodilator Agents | 2000 |
Dityrosine formation outcompetes tyrosine nitration at low steady-state concentrations of peroxynitrite. Implications for tyrosine modification by nitric oxide/superoxide in vivo.
Topics: Dimerization; Flavin Mononucleotide; Free Radicals; Hydrazines; Hypoxanthine; Kinetics; Nitrates; Nitric Oxide; Nitrogen Oxides; Spermine; Tyrosine; Xanthine Oxidase | 2000 |
Role of nitric oxide and peroxynitrite in bile salt-induced apoptosis: relevance to colon carcinogenesis.
Topics: Apoptosis; Bile Acids and Salts; Colonic Neoplasms; Deoxycholic Acid; Enzyme Inhibitors; Fluorescent Antibody Technique; Free Radical Scavengers; Humans; Microscopy, Confocal; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Oxidative Stress; Salicylates; Superoxides; Tumor Cells, Cultured; Tyrosine | 1999 |
Inhibition of MIP-1alpha-induced human neutrophil and monocyte chemotactic activity by reactive oxygen and nitrogen metabolites.
Topics: Chemokine CCL3; Chemokine CCL4; Chemotaxis, Leukocyte; Complement System Proteins; Deferoxamine; Humans; Hydrazines; In Vitro Techniques; Leukotriene B4; Macrophage Inflammatory Proteins; Molsidomine; Monocytes; Neutrophils; Nitrates; Nitric Oxide; Nitric Oxide Donors; Oxidants | 2000 |
Western blot analysis for nitrotyrosine protein adducts in livers of saline-treated and acetaminophen-treated mice.
Topics: Acetaminophen; Adjuvants, Immunologic; Analgesics, Non-Narcotic; Animals; Blotting, Western; Cattle; Chemical and Drug Induced Liver Injury; Enzyme-Linked Immunosorbent Assay; Hemocyanins; Immunoenzyme Techniques; Liver; Male; Mice; Mice, Inbred C57BL; Necrosis; Nitrates; Protein Binding; Proteins; Rabbits; Serum Albumin, Bovine; Sodium Chloride; Tyrosine | 2000 |
Different roles for nitrogen monoxide and peroxynitrite in lipid peroxidation induced by activated neutrophils.
Topics: Animals; Arginine; Carrageenan; Deferoxamine; Exudates and Transudates; Granuloma; Inflammation; Lipid Peroxidation; Male; Malondialdehyde; Neutrophils; Nitrates; Nitric Oxide; Ornithine; Oxidants; Pentetic Acid; Rats; Rats, Sprague-Dawley; Superoxide Dismutase; Superoxides | 2000 |
Free radicals and apoptosis of the endothelial cells.
Topics: Animals; Aorta; Apoptosis; Caspase 3; Caspases; DNA Fragmentation; Endothelium, Vascular; Free Radicals; Mice; Molsidomine; Nitrates; Nitric Oxide Donors; Oxidants; Swine | 2000 |
Apoptosis and formation of peroxynitrite in the lungs of patients with obliterative bronchiolitis.
Topics: Apoptosis; Biopsy; Bronchiolitis Obliterans; Graft Rejection; Humans; Immunohistochemistry; In Situ Nick-End Labeling; Lung Transplantation; Nitrates; Oxidants; Predictive Value of Tests | 2000 |
Scavengers for peroxynitrite: inhibition of tyrosine nitration and oxidation with tryptamine derivatives, alpha-lipoic acid and synthetic compounds.
Topics: Antioxidants; Chromatography, High Pressure Liquid; DNA Damage; Free Radical Scavengers; Indicators and Reagents; Nitrates; Oxidation-Reduction; Plasmids; Spectrophotometry, Ultraviolet; Spin Trapping; Thioctic Acid; Tryptamines; Tyrosine | 2000 |
Effects of tempol, a membrane-permeable radical scavenger, in a rodent model of carrageenan-induced pleurisy.
Topics: Animals; Carrageenan; Cells, Cultured; Cyclic N-Oxides; DNA Damage; Free Radical Scavengers; Hydrogen Peroxide; Lung; Macrophages; Male; Mitochondria; Nitrates; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Oxidants; Oxygen Consumption; Permeability; Pleurisy; Poly(ADP-ribose) Polymerases; Rats; Rats, Sprague-Dawley; Spin Labels; Tyrosine | 2000 |
The decomposition of peroxynitrite to nitroxyl anion (NO-) and singlet oxygen in aqueous solution.
Topics: Animals; Cattle; Free Radicals; Methemoglobin; Nitrates; Oxygen; Singlet Oxygen; Sodium Bicarbonate; Solutions; Water | 2000 |
Antioxidant properties of essential oils. Possible explanations for their anti-inflammatory effects.
Topics: Amino Acids; Amino Acids, Cyclic; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Cell Degranulation; Drug Combinations; Eucalyptus; Free Radical Scavengers; Granulocytes; Humans; In Vitro Techniques; Indicators and Reagents; Leukocytes; Methionine; Monoterpenes; Nitrates; Nitric Oxide; Oils, Volatile; Oxidants; Plant Oils; Plants, Medicinal; Terpenes | 2000 |
Rapid reactions of peroxynitrite with heme-thiolate proteins as the basis for protection of prostacyclin synthase from inactivation by nitration.
Topics: Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Hemeproteins; Horseradish Peroxidase; Intramolecular Oxidoreductases; Kinetics; Models, Biological; Nitrates; Tyrosine | 2000 |
Regulation of xanthine oxidase by nitric oxide and peroxynitrite.
Topics: Electron Spin Resonance Spectroscopy; Molybdenum; Nitrates; Nitric Oxide; Nitric Oxide Donors; Superoxides; Xanthine Oxidase | 2000 |
Diffusion of peroxynitrite into the human platelet inhibits cyclooxygenase via nitration of tyrosine residues.
Topics: Blood Platelets; Cell Membrane; Cell Membrane Permeability; Chromatography, High Pressure Liquid; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Diffusion; Eicosanoids; Gas Chromatography-Mass Spectrometry; Humans; Immunoblotting; In Vitro Techniques; Indicators and Reagents; Isoenzymes; Membrane Proteins; Nitrates; Oxidants; Platelet Activation; Platelet Aggregation; Prostaglandin-Endoperoxide Synthases; Thromboxane A2; Tyrosine; Vasoconstriction | 2000 |
Inhibition of inflammatory species by titanium surfaces.
Topics: Biocompatible Materials; Implants, Experimental; Inflammation; Inflammation Mediators; Nitrates; Reactive Oxygen Species; Surface Properties; Titanium | 2000 |
Generation of peroxynitrite in localised, moderate temperature burns.
Topics: Animals; Biomarkers; Burns; Culture Techniques; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Injury Severity Score; Male; Nitrates; Nitric Oxide; Oxidants; Probability; Rats; Rats, Wistar; Sensitivity and Specificity; Skin; Superoxides | 2000 |
Uric acid, a peroxynitrite scavenger, inhibits CNS inflammation, blood-CNS barrier permeability changes, and tissue damage in a mouse model of multiple sclerosis.
Topics: Animals; Apoptosis; Blood-Brain Barrier; Disease Models, Animal; Encephalomyelitis, Autoimmune, Experimental; Female; Free Radical Scavengers; Mice; Multiple Sclerosis; Nitrates; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Spinal Cord; Tyrosine; Uric Acid | 2000 |
Responses to peroxynitrite in yeast: glyceraldehyde-3-phosphate dehydrogenase (GAPDH) as a sensitive intracellular target for nitration and enhancement of chaperone expression and ubiquitination.
Topics: Animals; Astrocytes; Cell Culture Techniques; Cell Survival; Dithionitrobenzoic Acid; Dose-Response Relationship, Drug; Fungal Proteins; Glyceraldehyde-3-Phosphate Dehydrogenases; HSP70 Heat-Shock Proteins; Hydrogen Peroxide; Molecular Chaperones; Nitrates; Oxidants; Rats; Rats, Wistar; Saccharomyces cerevisiae; Sulfhydryl Compounds; Sulfhydryl Reagents; Tyrosine; Ubiquitins; Up-Regulation | 2000 |
Ascorbate is a potent antioxidant against peroxynitrite-induced oxidation reactions. Evidence that ascorbate acts by re-reducing substrate radicals produced by peroxynitrite.
Topics: Animals; Antioxidants; Ascorbic Acid; Cattle; Free Radicals; NAD; Nitrates; Oxidation-Reduction; Rhodamines | 2000 |
Role of peroxynitrite in altered fetal-placental vascular reactivity in diabetes or preeclampsia.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adult; Angiotensin II; Antihypertensive Agents; Diabetes Mellitus, Type 1; Epoprostenol; Female; Fetus; Humans; In Vitro Techniques; Muscle, Smooth, Vascular; Nitrates; Nitric Oxide; Nitroglycerin; Oxidative Stress; Placenta; Pre-Eclampsia; Pregnancy; Reactive Oxygen Species; Tyrosine; Vasoconstriction; Vasoconstrictor Agents; Vasodilator Agents | 2000 |
Peroxynitrite-induced DNA damage in the supF gene: correlation with the mutational spectrum.
Topics: Base Sequence; DNA; DNA Damage; Dose-Response Relationship, Drug; Genes, Suppressor; Guanine; Mass Spectrometry; Mutation; Nitrates; Oligonucleotides; Oxidants; Plasmids; RNA, Transfer | 2000 |
Inhibition of neutrophil superoxide production by uremic concentrations of guanidino compounds.
Topics: Adenosine Triphosphate; Cell Adhesion; Dose-Response Relationship, Drug; Energy Metabolism; Guanidines; Humans; Lactic Acid; Luminescent Measurements; Neutrophils; Nitrates; Osmolar Concentration; Phosphocreatine; Superoxides; Uremia | 2000 |
Reactive nitrogen and oxygen species attenuate interleukin- 8-induced neutrophil chemotactic activity in vitro.
Topics: Chemotaxis, Leukocyte; Humans; Interleukin-8; Leukotriene B4; Molsidomine; Neutrophils; Nitrates; Nitric Oxide Donors; Tyrosine | 2000 |
Involvement of peroxynitrite and hydroxyradical generated from nitric oxide in hypoxia/reoxygenation injury in rat cerebrocortical slices.
Topics: Adenosine Triphosphate; Animals; Cell-Free System; Cerebral Cortex; Cyclic AMP; Enzyme Inhibitors; Hydroxyl Radical; Hypoxia; Male; Neurons; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Oxidants; Poly(ADP-ribose) Polymerase Inhibitors; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Salicylates; Tyrosine | 2000 |
Nitration of manganese superoxide dismutase in cerebrospinal fluids is a marker for peroxynitrite-mediated oxidative stress in neurodegenerative diseases.
Topics: Adult; Aged; Alzheimer Disease; Antibodies; Biomarkers; Female; Humans; Male; Middle Aged; Nitrates; Nitrogen; Oxidative Stress; Parkinson Disease; Precipitin Tests; Superoxide Dismutase; Tyrosine | 2000 |
Peroxynitrite-mediated nitration of the stable free radical tyrosine residue of the ribonucleotide reductase small subunit.
Topics: Amino Acid Sequence; Catalysis; Chromatography, High Pressure Liquid; Conserved Sequence; Dimerization; Dose-Response Relationship, Drug; Escherichia coli; Free Radicals; Hydrogen-Ion Concentration; Mass Spectrometry; Models, Molecular; Molecular Weight; Nitrates; Nonheme Iron Proteins; Protein Structure, Quaternary; Ribonucleotide Reductases; Sequence Analysis, Protein; Spectrophotometry; Tyrosine | 2000 |
Cytochrome c nitration by peroxynitrite.
Topics: Animals; Binding Sites; Cytochrome c Group; Horses; Kinetics; Mass Spectrometry; Mitochondria, Heart; Models, Molecular; Molecular Conformation; Nitrates; Oxidants; Peptide Mapping; Protein Conformation; Rats; Spectrophotometry; Trypsin | 2000 |
Hyperalgesia due to nerve injury-role of peroxynitrite.
Topics: Animals; Hyperalgesia; Hyperthermia, Induced; Immunohistochemistry; Male; Nerve Compression Syndromes; Nerve Crush; Nerve Degeneration; Neuralgia; Nitrates; Peripheral Nerve Injuries; Peripheral Nerves; Rats; Rats, Wistar; Tyrosine; Uric Acid | 2000 |
Reactions of heme peroxidases with peroxynitrite.
Topics: Animals; Guaiacol; Horseradish Peroxidase; Kinetics; Lactoperoxidase; Nitrates; Oxidoreductases; Plants; Substrate Specificity; Time Factors | 2000 |
Naloxone protects rat dopaminergic neurons against inflammatory damage through inhibition of microglia activation and superoxide generation.
Topics: Animals; Cells, Cultured; Dopamine; Immunohistochemistry; Inflammation; Interleukin-1; Lipopolysaccharides; Mesencephalon; Microglia; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Naloxone; Narcotic Antagonists; Neurons; Nitrates; Nitrites; Oxidants; Rats; Rats, Inbred F344; Stereoisomerism; Substantia Nigra; Superoxides; Tumor Necrosis Factor-alpha; Tyrosine 3-Monooxygenase | 2000 |
Kinetic and mechanistic studies of the peroxynitrite-mediated oxidation of oxymyoglobin and oxyhemoglobin.
Topics: Carbon Dioxide; Hydrogen-Ion Concentration; Myoglobin; Nitrates; Oxidation-Reduction; Oxyhemoglobins | 2000 |
4-Hydroxy-2,2,6,6-tetramethylpiperidine-1-oxyl (Tempol) inhibits peroxynitrite-mediated phenol nitration.
Topics: Animals; Antioxidants; Cyclic N-Oxides; Hydrogen-Ion Concentration; Hydroxylation; L-Lactate Dehydrogenase; Molsidomine; Nitrates; Nitro Compounds; Nitroso Compounds; PC12 Cells; Phenol; Rats; Spin Labels | 2000 |
Formation of N-nitrosamines and N-nitramines by the reaction of secondary amines with peroxynitrite and other reactive nitrogen species: comparison with nitrotyrosine formation.
Topics: Aniline Compounds; Hydrogen Peroxide; Hypochlorous Acid; Morpholines; Nitrates; Nitrobenzenes; Nitrosamines; Sodium Nitrite; Superoxides; Tyrosine | 2000 |
Reaction of uric acid with peroxynitrite and implications for the mechanism of neuroprotection by uric acid.
Topics: Bicarbonates; Carbon Dioxide; Free Radical Scavengers; Free Radicals; Humans; Hydrogen-Ion Concentration; Kinetics; Models, Biological; Neuroprotective Agents; Nitrates; Nitrogen Dioxide; Nitrous Acid; Oxidants; Peroxynitrous Acid; Temperature; Uric Acid | 2000 |
Peroxynitrite modulates the activation of p38 and extracellular regulated kinases in PC12 cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Activation; Epidermal Growth Factor; ErbB Receptors; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Nerve Growth Factor; Nitrates; p38 Mitogen-Activated Protein Kinases; PC12 Cells; Phosphorylation; Quinazolines; Rats; src-Family Kinases; Tyrphostins | 2000 |
Role of the carbonate radical anion in tyrosine nitration and hydroxylation by peroxynitrite.
Topics: Anions; Bicarbonates; Carbon Dioxide; Carbonates; Chromatography, High Pressure Liquid; Electron Spin Resonance Spectroscopy; Free Radicals; Hydrogen-Ion Concentration; Hydroxyl Radical; Hydroxylation; Kinetics; Nitrates; Nitric Oxide; Spectrophotometry, Ultraviolet; Tyrosine | 2000 |
Selective involvement of superoxide anion, but not downstream compounds hydrogen peroxide and peroxynitrite, in tumor necrosis factor-alpha-induced apoptosis of rat mesangial cells.
Topics: Animals; Apoptosis; Blotting, Northern; Cells, Cultured; Dose-Response Relationship, Drug; Glomerular Mesangium; Humans; Hydrogen Peroxide; Male; Microscopy, Fluorescence; NF-kappa B; Nitrates; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Signal Transduction; Superoxides; Transfection; Tumor Necrosis Factor-alpha | 2000 |
Formation of 8-nitroguanine from 2'-deoxyguanosine by NO/O2 system.
Topics: Deoxyguanosine; Guanine; Models, Chemical; Nitrates; Nitric Oxide; Oxidation-Reduction; Oxygen | 1999 |
Peroxynitrite-mediated release of arachidonic acid from PC12 cells.
Topics: Animals; Arachidonic Acid; Nitrates; Oxidants; PC12 Cells; Phospholipases A; Rats | 2000 |
Evidence for the involvement of peroxynitrite in ischaemic preconditioning in rat isolated hearts.
Topics: Animals; Antioxidants; Arrhythmias, Cardiac; Glycine; Ischemic Preconditioning, Myocardial; Male; Nitrates; Oxidants; Rats; Rats, Wistar; Sulfhydryl Compounds | 2000 |
Plasma proteins modified by tyrosine nitration in acute respiratory distress syndrome.
Topics: Acute Disease; Adult; alpha 1-Antichymotrypsin; Blood Proteins; Blotting, Western; Carbon Dioxide; Ceruloplasmin; Enzyme Activation; Fibrinogen; Humans; In Vitro Techniques; Nitrates; Nitric Oxide; Oxidative Stress; Precipitin Tests; Respiratory Distress Syndrome; Superoxides; Tyrosine | 2000 |
Carbon dioxide enhances nitration of surfactant protein A by activated alveolar macrophages.
Topics: Carbon Dioxide; Cells, Cultured; Enzyme Activation; Epithelial Cells; Humans; Hypercapnia; Lipid Metabolism; Lipopolysaccharides; Macrophages, Alveolar; Mass Spectrometry; Molsidomine; Nitrates; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitrites; Oxidation-Reduction; Proteolipids; Pulmonary Surfactant-Associated Protein A; Pulmonary Surfactant-Associated Proteins; Pulmonary Surfactants; Respiratory Distress Syndrome; Tyrosine | 2000 |
Elevated, sustained peroxynitrite levels as the cause of chronic fatigue syndrome.
Topics: Drug Therapy, Combination; Fatigue Syndrome, Chronic; Feedback; Humans; Hypothalamus; Nitrates | 2000 |
[Peroxynitrite production in cerebral ischemia].
Topics: Animals; Brain; Brain Ischemia; Nitrates; Oxidants; Rabbits; Rats | 1999 |
Increased nitrotyrosine staining in kidneys from patients with diabetic nephropathy.
Topics: Adolescent; Adult; Aged; Child; Diabetic Nephropathies; Female; Humans; Immunohistochemistry; Kidney; Male; Middle Aged; Nitrates; Tyrosine | 2000 |
Toxicity of ALS-linked SOD1 mutants.
Topics: Amyotrophic Lateral Sclerosis; Animals; Apoptosis; Cells, Cultured; Copper; Humans; Mice; Motor Neurons; Mutation; Neurofilament Proteins; Nitrates; Superoxide Dismutase; Superoxide Dismutase-1; Yeasts; Zinc | 2000 |
Synergistic depletion of astrocytic glutathione by glucose deprivation and peroxynitrite: correlation with mitochondrial dysfunction and subsequent cell death.
Topics: Animals; Astrocytes; Cell Survival; Drug Synergism; Glucose; Glutathione; Membrane Potentials; Mitochondria; Molsidomine; Nitrates; Nitric Oxide Donors; Nitroso Compounds; Penicillamine; Rats; Rats, Sprague-Dawley; S-Nitroso-N-Acetylpenicillamine; S-Nitrosoglutathione | 2000 |
Peroxynitrite targets the epidermal growth factor receptor, Raf-1, and MEK independently to activate MAPK.
Topics: Animals; Enzyme Activation; ErbB Receptors; MAP Kinase Signaling System; Nitrates; Oxidants; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins c-raf; Rats; Signal Transduction | 2000 |
The nitration of platelet cytosolic proteins during agonist-induced activation of platelets.
Topics: Aspirin; Blood Platelets; Blood Proteins; Blotting, Western; Cell Adhesion Molecules; Collagen; Cyclooxygenase Inhibitors; Cytosol; Enzyme-Linked Immunosorbent Assay; Humans; Membrane Proteins; Microfilament Proteins; Molecular Weight; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide Synthase; Nitrous Acid; Oxidants; Peroxynitrous Acid; Phosphoproteins; Platelet Activation; Thrombin; Tyrosine | 2000 |
Hydrogen peroxide- and peroxynitrite-induced mitochondrial DNA damage and dysfunction in vascular endothelial and smooth muscle cells.
Topics: Cells, Cultured; DNA Damage; DNA, Mitochondrial; Endothelium, Vascular; Humans; Hydrogen Peroxide; Mitochondria; Muscle, Smooth, Vascular; Nitrates; Oxidants; Protein Biosynthesis | 2000 |
A catalyst of peroxynitrite decomposition inhibits murine experimental autoimmune encephalomyelitis.
Topics: Animals; Catalysis; Central Nervous System; Encephalomyelitis, Autoimmune, Experimental; Female; Ferric Compounds; Immunohistochemistry; Lymphocyte Transfusion; Lymphocytes; Metalloporphyrins; Mice; Mice, Inbred Strains; Nitrates; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Tyrosine | 2000 |
Ebselen as a peroxynitrite scavenger in vitro and ex vivo.
Topics: Animals; Antioxidants; Aorta; Azoles; Cattle; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Interactions; Enzyme Inhibitors; Free Radical Scavengers; In Vitro Techniques; Intramolecular Oxidoreductases; Isoindoles; Nitrates; Organoselenium Compounds; Oxidants; Sulfhydryl Compounds | 2000 |
Role of nitric oxide in lipopolysaccharide-induced oxidant stress in the rat kidney.
Topics: Animals; Blood Urea Nitrogen; Blotting, Western; Creatine; Enzyme Inhibitors; Glutathione; Immunohistochemistry; Kidney; Lipid Peroxidation; Lipopolysaccharides; Lysine; Male; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; Oxidative Stress; Rats; Rats, Sprague-Dawley; Tyrosine | 2000 |
Chemiluminescent aldehyde and beta-diketone reactions promoted by peroxynitrite.
Topics: Aldehydes; Luminescent Measurements; Nitrates; Oxidants; Pentanes; Spin Trapping | 2000 |
A novel nitration product formed during the reaction of peroxynitrite with 2',3',5'-tri-O-acetyl-7,8-dihydro-8-oxoguanosine: N-nitro-N'-[1-(2,3,5-tri-O-acetyl-beta-D-erythro-pentofuranosyl)- 2, 4-dioxoimidazolidin-5-ylidene]guanidine.
Topics: Circular Dichroism; Guanidines; Guanosine; Magnetic Resonance Spectroscopy; Mass Spectrometry; Nitrates; Oxidants; Spectrophotometry, Ultraviolet | 2000 |
Cooperation between reactive oxygen and nitrogen intermediates in killing of Rhodococcus equi by activated macrophages.
Topics: Actinomycetales Infections; Animals; Free Radicals; Interferon-gamma; Macrophage Activation; Macrophages; Membrane Glycoproteins; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Mutant Strains; NADPH Oxidase 2; NADPH Oxidases; Nitrates; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrogen Oxides; Phagocytosis; Reactive Oxygen Species; Rhodococcus equi | 2000 |
Poly(ADP-ribose) synthase inhibition reduces ischemic injury and inflammation in neonatal rat brain.
Topics: Animals; Animals, Newborn; Benzamides; Brain Ischemia; Cell Death; Cerebral Infarction; Encephalitis; Female; Male; Motor Activity; Neurologic Examination; Neuroprotective Agents; Neutrophils; Nitrates; Poly(ADP-ribose) Polymerase Inhibitors; Polymers; Rats; Rats, Wistar; Reperfusion Injury; Signal Transduction; Stroke; Time Factors; Tyrosine | 2000 |
Molecular mechanisms of increased nitric oxide (NO) in asthma: evidence for transcriptional and post-translational regulation of NO synthesis.
Topics: Adult; Alternative Splicing; Arginine; Asthma; Bronchi; Bronchoalveolar Lavage Fluid; DNA-Binding Proteins; Epithelial Cells; Female; Fluocinolone Acetonide; Humans; Interferon-gamma; Janus Kinase 1; Male; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Protein Processing, Post-Translational; Protein-Tyrosine Kinases; Reactive Oxygen Species; RNA, Messenger; STAT1 Transcription Factor; Trans-Activators; Transcription, Genetic; Tyrosine | 2000 |
Nitric oxide donor-induced increase in permeability of the blood-brain barrier.
Topics: Animals; Arterioles; Blood-Brain Barrier; Capillary Permeability; Cerebral Arteries; Male; Nitrates; Nitric Oxide; Nitric Oxide Donors; Rats; Rats, Wistar; Superoxides; Vasodilation | 2000 |
Peroxynitrite production by TNF-alpha and IL-1beta: implication for suppression of osteoblastic differentiation.
Topics: Alkaline Phosphatase; Animals; Cell Line; Drug Synergism; Free Radical Scavengers; Gene Expression; Interleukin-1; Mice; Nitrates; Nitric Oxide Donors; Osteoblasts; Osteocalcin; Pyrogallol; RNA, Messenger; Superoxide Dismutase; Superoxides; Tumor Necrosis Factor-alpha | 2000 |
Scavenging of peroxynitrite by oxyhemoglobin and identification of modified globin residues.
Topics: Ascorbic Acid; Carbon Dioxide; Dipeptides; Erythrocytes; Free Radical Scavengers; Globins; Humans; Immunoelectrophoresis; Mass Spectrometry; Nitrates; Oxyhemoglobins; Tyrosine | 2000 |
A discussion of the chemistry of oxidative and nitrosative stress in cytotoxicity.
Topics: Animals; Cell Survival; Nitrates; Nitric Oxide; Oxidative Stress; Superoxides | 2000 |
Beneficial effects of peroxynitrite decomposition catalyst in a rat model of splanchnic artery occlusion and reperfusion.
Topics: Animals; Blood Pressure; Catalysis; Celiac Artery; Disease Models, Animal; Endothelium, Vascular; Ferric Compounds; Ileum; Intercellular Adhesion Molecule-1; Leukocyte Count; Lipid Peroxidation; Male; Malondialdehyde; Metalloporphyrins; Nitrates; Nitric Oxide; Nitrites; Oxidative Stress; P-Selectin; Peroxidase; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Rhodamines; Splanchnic Circulation; Tyrosine | 2000 |
Transformations of 2,6-diisopropylphenol by NO-derived nitrogen oxides, particularly peroxynitrite.
Topics: Anesthetics, Intravenous; Bicarbonates; Biotransformation; Chromatography, High Pressure Liquid; Mass Spectrometry; Nitrates; Nitric Oxide; Nitrogen Oxides; Oxidants; Propofol | 2000 |
Two distinct mechanisms of nitric oxide-mediated neuronal cell death show thiol dependency.
Topics: Acetylcysteine; Animals; Cell Death; Cell Differentiation; Cell Line; Cell Survival; Cyclic GMP; Hydrazines; Molsidomine; Necrosis; Neurons; Nitrates; Nitric Oxide; Nitric Oxide Donors; Oxidants; Sulfhydryl Compounds | 2000 |
Peroxynitrite reversibly inhibits Ca(2+)-activated K(+) channels in rat cerebral artery smooth muscle cells.
Topics: Animals; Bradykinin; Calcium; Cerebral Arteries; Electrophysiology; Ion Channels; Male; Muscle, Smooth, Vascular; Nitrates; Oxidants; Potassium Channel Blockers; Potassium Channels; Rats; Rats, Wistar; Sulfhydryl Compounds | 2000 |
The quantitative oxidation of methionine to methionine sulfoxide by peroxynitrite.
Topics: Aldehydes; Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Dose-Response Relationship, Drug; Ethylenes; Hydrogen-Ion Concentration; Kinetics; Methionine; Models, Chemical; Nitrates; Nitrites; Nitrous Acid; Peroxynitrous Acid; Spectrophotometry; Time Factors | 2000 |
Tyrosine nitration of c-SRC tyrosine kinase in human pancreatic ductal adenocarcinoma.
Topics: Adenocarcinoma; Blotting, Western; Chromatography, High Pressure Liquid; Cortactin; Humans; Microfilament Proteins; Nitrates; Pancreatic Neoplasms; Phosphorylation; Phosphotyrosine; Precipitin Tests; Protein Conformation; Protein Folding; Proto-Oncogene Proteins pp60(c-src); Tumor Cells, Cultured; Tyrosine | 2000 |
Cis- and trans-conformations for peroxynitrite anions.
Topics: Anions; Models, Chemical; Nitrates; Spectrum Analysis, Raman; Stereoisomerism; Temperature | 2000 |
A new route to peroxynitrite: a role for xanthine oxidoreductase.
Topics: Animals; Cattle; Dose-Response Relationship, Drug; Inorganic Chemicals; Kinetics; Milk; Models, Chemical; Nitrates; Nitrites; Oxidation-Reduction; Oxygen; Pterins; Superoxide Dismutase; Xanthine Dehydrogenase; Xanthine Oxidase | 2000 |
Neuronal death in newborn striatum after hypoxia-ischemia is necrosis and evolves with oxidative stress.
Topics: Animals; Animals, Newborn; Brain Ischemia; Cell Death; Corpus Striatum; Cytochrome c Group; DNA Damage; Endoplasmic Reticulum; Female; Glutathione; Golgi Apparatus; Hydroxyl Radical; Hypoxia; Lysosomes; Male; Mitochondria; Necrosis; Neurons; Nitrates; Oxidants; Oxidative Stress; Swine | 2000 |
Oxidation of ubiquinol by peroxynitrite: implications for protection of mitochondria against nitrosative damage.
Topics: Albumins; Animals; Coenzymes; Dose-Response Relationship, Drug; Electron Spin Resonance Spectroscopy; Immunoblotting; Kinetics; Mitochondria; Mitochondria, Liver; Models, Chemical; Nitrates; Oxidation-Reduction; Oxidative Stress; Oxygen; Oxygen Consumption; Protein Binding; Rats; Spectrophotometry; Time Factors; Tyrosine; Ubiquinone | 2000 |
Apocynin inhibits peroxynitrite formation by murine macrophages.
Topics: Acetophenones; Acridines; Animals; Antioxidants; Cell Line; Cyclic N-Oxides; Dose-Response Relationship, Drug; Enzyme Inhibitors; Guanidines; Interferon-gamma; Lipopolysaccharides; Luminescent Measurements; Macrophages; Mice; Molsidomine; Nitrates; Nitric Oxide Synthase; Oxidation-Reduction; Rhodamines | 2000 |
Endothelial cell calcium mobilization to acetylcholine is attenuated in copper-deficient rats.
Topics: Acetylcholine; Animals; Arginine; Arterioles; Calcium; Copper; Diet; Endothelium, Vascular; In Vitro Techniques; Male; Muscle, Skeletal; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Oxidants; Oxidative Stress; Rats; Rats, Sprague-Dawley; Signal Transduction; Vasodilation; Vasodilator Agents | 2000 |
Osteopontin is induced by nitric oxide in RAW 264.7 cells.
Topics: Animals; beta-Aminoethyl Isothiourea; Blotting, Northern; Cell Line; Enzyme Inhibitors; Humans; Interferon-gamma; Kinetics; Lipopolysaccharides; Macrophages; Mice; Nitrates; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrogen Oxides; omega-N-Methylarginine; Osteopontin; Oxidants; RNA, Messenger; Sialoglycoproteins; Spermine; Time Factors | 2000 |
Oxidant stress in rat liver after lipopolysaccharide administration: effect of inducible nitric-oxide synthase inhibition.
Topics: Animals; Blotting, Western; Enzyme Inhibitors; Glutathione; Lipopolysaccharides; Liver; Male; Nitrates; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Oxidative Stress; Rats; Rats, Sprague-Dawley | 2000 |
Cardiac peroxynitrite formation and left ventricular dysfunction following doxorubicin treatment in mice.
Topics: Animals; Antibiotics, Antineoplastic; Creatine Kinase; Doxorubicin; Immunohistochemistry; Male; Mice; Myocardium; Nitrates; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Tyrosine; Ventricular Dysfunction, Left | 2000 |
Peroxynitrite-generating species: good candidate oxidants in aqueous extracts of cigarette smoke.
Topics: Arteriosclerosis; Humans; Nicotiana; Nitrates; Oxidants; Plants, Toxic; Smoke; Smoking; Tyrosine | 2000 |
Gr-1+ myeloid cells derived from tumor-bearing mice inhibit primary T cell activation induced through CD3/CD28 costimulation.
Topics: Animals; Antibodies, Monoclonal; Bone Marrow Cells; CD28 Antigens; CD3 Complex; Cell Count; Cell Division; Cell Separation; Cells, Cultured; Coculture Techniques; Female; Hematopoietic Stem Cells; Immune Tolerance; Interferon-gamma; Interphase; Lymphocyte Activation; Macrophage-1 Antigen; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Neoplasms, Experimental; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; omega-N-Methylarginine; Spleen; T-Lymphocytes | 2000 |
Protection by a manganese porphyrin of endogenous peroxynitrite-induced death of glial cells via inhibition of mitochondrial transmembrane potential decrease.
Topics: Animals; Animals, Newborn; Cell Death; Cells, Cultured; Glucose; Intracellular Membranes; Membrane Potentials; Mitochondria; Neuroglia; Nitrates; Organometallic Compounds; Porphyrins; Rats; Rats, Sprague-Dawley | 2000 |
The decomposition of peroxynitrite does not yield nitroxyl anion and singlet oxygen.
Topics: Animals; Anions; Cattle; Free Radicals; Hydrogen Peroxide; Methemoglobin; Nitrates; Nitrites; Nitrogen Dioxide; Nitrogen Oxides; Oxygen; Singlet Oxygen; Spectrophotometry, Ultraviolet | 2000 |
Modeling the interaction of peroxynitrite with low-density lipoproteins. I. Plasma levels of peroxynitrite.
Topics: Arteriosclerosis; Humans; Lipid Peroxidation; Lipoproteins, LDL; Models, Chemical; Nitrates; Reactive Oxygen Species | 2000 |
Modeling the interaction of peroxynitrite with low-density lipoproteins. II: reaction/diffusion model of peroxynitrite in low-density lipoprotein particles.
Topics: Arteriosclerosis; Diffusion; Humans; Lipid Peroxidation; Lipoproteins, LDL; Models, Chemical; Nitrates | 2000 |
Modeling the interaction of peroxynitrite with low-density lipoproteins. III: the role of antioxidants.
Topics: Antioxidants; Arteriosclerosis; Humans; Lipid Peroxidation; Lipoproteins, LDL; Models, Chemical; Nitrates | 2000 |
Interaction of nitric oxide and reactive oxygen species on rat diaphragm contractility.
Topics: Analysis of Variance; Animals; Antioxidants; Azoles; Diaphragm; Enzyme Inhibitors; Hypoxanthine; In Vitro Techniques; Isoindoles; Muscle Contraction; Nitrates; Nitric Oxide; Nitroarginine; Nitroprusside; Organoselenium Compounds; Rats; Rats, Inbred F344; Reactive Oxygen Species; Vasodilator Agents; Xanthine Oxidase | 2000 |
Differential regulation of nitric oxide synthase isoforms in experimental acute chagasic cardiomyopathy.
Topics: Acute Disease; Animals; Chagas Cardiomyopathy; Disease Models, Animal; Isoenzymes; Male; Malondialdehyde; Myocardium; Nitrates; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Nitrites; Rats; Rats, Inbred Lew; RNA, Messenger | 2000 |
Inhibition of nitric oxide synthase ameliorates cellular injury in sickle cell mouse kidneys.
Topics: Alanine Transaminase; Anemia, Sickle Cell; Animals; Apoptosis; Aspartate Aminotransferases; Blotting, Western; Cell Hypoxia; DNA Fragmentation; Electrophoresis, Agar Gel; Enzyme Inhibitors; Guanidines; Immunohistochemistry; In Situ Nick-End Labeling; Kidney Diseases; Kidney Tubules; Mice; Mice, Inbred C57BL; Mice, Transgenic; Nitrates; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Poly(ADP-ribose) Polymerases; Tyrosine | 2000 |
Antiperoxynitrite strategies for the experimental therapy of shock.
Topics: Animals; Nitrates; Oxidants; Shock | 2000 |
Peroxynitrite-induced secondary oxidative lesions at guanine nucleobases: chemical stability and recognition by the Fpg DNA repair enzyme.
Topics: Chromatography, High Pressure Liquid; DNA; DNA Repair; DNA-Formamidopyrimidine Glycosylase; Guanine; N-Glycosyl Hydrolases; Nitrates; Oligonucleotides; Oxidants; Oxidation-Reduction; Piperidines; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 2000 |
Reaction of phenylaminoethyl selenides with peroxynitrite and hydrogen peroxide.
Topics: Antihypertensive Agents; Antioxidants; Ascorbic Acid; Chromatography, High Pressure Liquid; Ethylamines; Hydrogen Peroxide; Hydrogen-Ion Concentration; Kinetics; Molecular Structure; Nitrates; Organoselenium Compounds; Oxidants; Oxidation-Reduction; Oxides; Oxidoreductases; Phenethylamines; Reactive Oxygen Species; Sulfur Compounds; Thermodynamics | 2000 |
Helicobacter pylori urease suppresses bactericidal activity of peroxynitrite via carbon dioxide production.
Topics: Ammonia; Anti-Bacterial Agents; Carbon Dioxide; Drug Interactions; Helicobacter pylori; Microbial Sensitivity Tests; Nitrates; Oxidants; Sodium Bicarbonate; Tyrosine; Urea; Urease | 2000 |
Astrocyte-derived nitric oxide causes both reversible and irreversible damage to the neuronal mitochondrial respiratory chain.
Topics: Animals; Animals, Newborn; Astrocytes; Cell Survival; Cells, Cultured; Cerebral Cortex; Citrate (si)-Synthase; Coculture Techniques; Electron Transport Complex II; Electron Transport Complex III; Electron Transport Complex IV; Kinetics; Mitochondria; Multienzyme Complexes; NADH Dehydrogenase; Neurons; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Oxidants; Oxidoreductases; Oxygen Consumption; Rats; Rats, Wistar; Succinate Dehydrogenase | 2000 |
Tyrosine nitration by peroxynitrite formed from nitric oxide and superoxide generated by xanthine oxidase.
Topics: Humans; Kinetics; Nitrates; Nitric Oxide; Oxidants; Peroxidase; Sputum; Superoxides; Tyrosine; Xanthine Oxidase | 2000 |
Superoxide reacts with nitric oxide to nitrate tyrosine at physiological pH via peroxynitrite.
Topics: Hydrogen-Ion Concentration; Kinetics; Nitrates; Nitric Oxide; Nitric Oxide Donors; Nitrogen Oxides; Oxidants; Photochemistry; Spectrophotometry; Spermine; Superoxides; Tyrosine; Xanthine Oxidase | 2000 |
Making and working with peroxynitrite.
Topics: Animals; Calcium; Fluorescent Dyes; Indicators and Reagents; Muscle Relaxation; Muscle, Smooth, Vascular; Nitrates; Nitric Oxide; Oxidants; Oxidation-Reduction; PC12 Cells; Rats; Safety | 1998 |
Measurement of DNA damage using the comet assay.
Topics: Animals; Cell Culture Techniques; Cell Line; Cells, Cultured; Comet Assay; DNA; DNA Damage; Electrophoresis, Agar Gel; Indicators and Reagents; Microscopy, Fluorescence; Nitrates; Nitric Oxide; Oxidants | 1998 |
Peroxynitrite-induced apoptosis involves activation of multiple caspases in HL-60 cells.
Topics: Apoptosis; Caspases; HL-60 Cells; Humans; Lamin Type B; Lamins; Nitrates; Nuclear Proteins; Oxidants; Poly(ADP-ribose) Polymerases | 2000 |
Contrasting effects of NO and peroxynitrites on HSP70 expression and apoptosis in human monocytes.
Topics: Apoptosis; Cells, Cultured; Free Radical Scavengers; HSP70 Heat-Shock Proteins; Humans; Monocytes; Nitrates; Nitric Oxide; Oxidants | 2000 |
Reactions of peroxynitrite with cocoa procyanidin oligomers.
Topics: Biflavonoids; Cacao; Catechin; Chromatography, High Pressure Liquid; Drug Interactions; Nitrates; Oxidants; Oxidation-Reduction; Proanthocyanidins; Rhodamines; Structure-Activity Relationship; Tyrosine | 2000 |
Immunolocalization of inducible nitric oxide synthase and 3-nitrotyrosine in the nasal mucosa of patients with rhinitis.
Topics: Adolescent; Adult; Enzyme Induction; Female; Humans; Immunoenzyme Techniques; Male; Middle Aged; Nasal Mucosa; Nitrates; Nitric Oxide Synthase; Rhinitis; Rhinitis, Allergic, Perennial; Turbinates; Tyrosine | 2000 |
Physiological effects of peroxynitrite: potential products of the environment.
Topics: Animals; Blood Physiological Phenomena; Cats; Crystalloid Solutions; Cytokines; Glutathione; Heart; Heart Diseases; Heart Ventricles; Humans; Isotonic Solutions; Myocardial Infarction; Nitrates; Nitric Oxide; Perfusion; Plasma Substitutes; Superoxides; Tyrosine | 2000 |
Peroxynitrite is a major contributor to cytokine-induced myocardial contractile failure.
Topics: 1,2-Dihydroxybenzene-3,5-Disulfonic Acid Disodium Salt; Animals; Electron Spin Resonance Spectroscopy; Free Radical Scavengers; Heart; Heart Failure; Inflammation; Interferon-gamma; Interleukin-1; Male; Muscle Proteins; Myocardial Contraction; Myocardium; NADPH Oxidases; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitroarginine; Oxidation-Reduction; Oxidative Stress; Perfusion; Porphyrins; Rats; Rats, Sprague-Dawley; Superoxides; Tumor Necrosis Factor-alpha; Xanthine Oxidase | 2000 |
Role of endothelial nitric oxide generation and peroxynitrite formation in reperfusion injury after focal cerebral ischemia.
Topics: Animals; Biomarkers; Blood-Brain Barrier; Coloring Agents; Endothelium, Vascular; Enzyme Inhibitors; Evans Blue; Indazoles; Infarction, Middle Cerebral Artery; Matrix Metalloproteinase 9; Mice; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Oxidants; Permeability; Reperfusion Injury; Tyrosine | 2000 |
The mechanism of nitric oxide and/or superoxide cytotoxicity in endothelial cells.
Topics: Animals; Catalase; Cattle; Cell Death; Cells, Cultured; Endothelium, Vascular; Glutathione; Hemoglobins; Hydrogen Peroxide; Maleates; Molsidomine; Nitrates; Nitric Oxide; Nitrites; Pyrogallol; Sulfhydryl Compounds; Superoxide Dismutase; Superoxides | 2000 |
Immature brain injury via peroxynitrite production induced by inducible nitric oxide synthase after hypoxia-ischemia in rats.
Topics: Animals; Animals, Newborn; Brain Diseases; Carotid Arteries; Hypoxia-Ischemia, Brain; Kinetics; Ligation; Nitrates; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Rats; Rats, Wistar; RNA, Messenger; Tyrosine | 2000 |
The role of oxygen and reduced oxygen species in nitric oxide-mediated cytotoxicity: studies in the yeast Saccharomyces cerevisiae model system.
Topics: Hydrogen Peroxide; Nitrates; Nitric Oxide; Oxygen; Saccharomyces cerevisiae | 2000 |
Phenolic acids protect low density lipoproteins from peroxynitrite-mediated modification in vitro.
Topics: Caffeic Acids; Coumaric Acids; Humans; Kinetics; Lipoproteins, LDL; Molsidomine; Nitrates; Nitric Oxide Donors; Oxidants; Vitamin E | 2000 |
Inactivation of antioxidant enzymes by peroxynitrite.
Topics: Catalase; Enzyme Inhibitors; Glutathione Peroxidase; Humans; Nitrates; Oxidative Stress; Superoxide Dismutase | 2000 |
Nitric oxide and peroxynitrite anion modulate liver plasma membrane fluidity and Na(+)/K(+)-ATPase activity.
Topics: Animals; Cell Fractionation; Cell Polarity; Enzyme Activation; Fluorescence Polarization; Liver; Male; Membrane Fluidity; Molsidomine; Nitrates; Nitric Oxide; Nitric Oxide Donors; Penicillamine; Rats; Rats, Wistar; Sodium-Potassium-Exchanging ATPase | 2000 |
Nitric oxide and its metabolites mediate ethanol-induced microtubule disruption and intestinal barrier dysfunction.
Topics: Antioxidants; Blotting, Western; Caco-2 Cells; Enzyme Activation; Enzyme Inhibitors; Ethanol; Fluorescent Antibody Technique; Humans; Intestinal Mucosa; Microscopy, Confocal; Microtubules; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Oxidative Stress; Superoxides; Tubulin | 2000 |
Poly (ADP-ribose) synthetase mediates intestinal mucosal barrier dysfunction after mesenteric ischemia.
Topics: Animals; Arterial Occlusive Diseases; Chemotaxis, Leukocyte; DNA Damage; Energy Metabolism; Enzyme Induction; Enzyme Inhibitors; Ileum; Intestinal Mucosa; Ischemia; Lipid Peroxidation; Liver; Lung; Male; Mesenteric Artery, Superior; Mesentery; Mice; Mice, Inbred C57BL; Mice, Knockout; Neutrophil Infiltration; Neutrophils; Nitrates; Nitric Oxide Synthase; omega-N-Methylarginine; Oxidative Stress; Peroxidase; Poly(ADP-ribose) Polymerases; Rats; Rats, Wistar; Reperfusion Injury | 2000 |
Beneficial effects of tempol, a membrane-permeable radical scavenger, in a rodent model of splanchnic artery occlusion and reperfusion.
Topics: Animals; Arterial Occlusive Diseases; Celiac Artery; Cell Membrane Permeability; Constriction; Cyclic N-Oxides; Drug Evaluation, Preclinical; Enzyme Induction; Free Radical Scavengers; Ileum; Intercellular Adhesion Molecule-1; Lipid Peroxidation; Male; Malondialdehyde; Mesenteric Artery, Superior; Nitrates; P-Selectin; Peroxidase; Poly(ADP-ribose) Polymerases; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Spin Labels; Splanchnic Circulation | 2000 |
Prostaglandin E1 reduces ischemia/reperfusion injury by normalizing nitric oxide and superoxide release.
Topics: Acetylcholine; Alprostadil; Animals; Drug Evaluation, Preclinical; Hindlimb; Ischemia; Male; Muscle, Skeletal; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Rabbits; Reperfusion Injury; Superoxides; Vasoconstriction | 2000 |
Nitric oxide synthase and tissue injury.
Topics: Alprostadil; Animals; Arginine; Burns; Enzyme Inhibitors; Humans; Ischemia; Luminescent Measurements; Models, Biological; Nitrates; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Oxidative Stress; Reperfusion Injury; Sepsis; Shock; Superoxides; Tyrosine | 2000 |
Effects of peroxynitrite on rabbit cornea.
Topics: Animals; Anterior Chamber; Corneal Edema; Endothelium, Corneal; Injections; Microscopy, Electron, Scanning; Mitochondria; Molsidomine; Nitrates; Nitric Oxide Donors; Rabbits; Superoxides; Ultrasonography | 2000 |
Reactivity of peroxynitrite versus simultaneous generation of (*)NO and O(2)(*)(-) toward NADH.
Topics: Bicarbonates; Hydroxyl Radical; Kinetics; NAD; Nitrates; Nitric Oxide; Oxidants; Oxidation-Reduction; Pulse Radiolysis; Reactive Oxygen Species | 2000 |
Potentiation of carbachol-induced Ca2+ release by peroxynitrite in human neuroblastoma SH-SY5Y cells.
Topics: Calcium; Carbachol; Genistein; Humans; Molsidomine; Neuroblastoma; Nitrates; Phosphorylation; Tumor Cells, Cultured; Tyrosine | 2000 |
P-selectin participates in cardiopulmonary bypass-induced inflammatory response in association with nitric oxide and peroxynitrite production.
Topics: Animals; Antibodies, Monoclonal; Cardiopulmonary Bypass; Inflammation; Interleukin-6; Male; Nitrates; Nitric Oxide; Nitrites; P-Selectin; Rats; Rats, Sprague-Dawley; Tyrosine | 2000 |
Effects of n-acetylcysteine in a rat model of ischemia and reperfusion injury.
Topics: Acetylcholine; Acetylcysteine; Analysis of Variance; Animals; Aorta; Fluorescent Antibody Technique, Indirect; Free Radical Scavengers; Ileum; In Vitro Techniques; Intercellular Adhesion Molecule-1; Leukocyte Count; Lipid Peroxidation; Male; Malondialdehyde; Nitrates; Nitrites; P-Selectin; Peroxidase; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Splenic Artery; Tyrosine; Vasodilation | 2000 |
Glutathione protects against myocardial ischemia-reperfusion injury by detoxifying peroxynitrite.
Topics: Animals; Glutathione; Myocardial Ischemia; Myocardial Reperfusion Injury; Nitrates; Oxidants; Oxidation-Reduction; Rats | 2000 |
Nitration and hydroxylation of aromatic amino acid and guanine by the air pollutant peroxyacetyl nitrate.
Topics: Air Pollutants; Amino Acids, Cyclic; Chromatography, High Pressure Liquid; Guanine; HL-60 Cells; Humans; Hydroxylation; Mass Spectrometry; Nitrates; Nitrogen; Oxidants; Peracetic Acid; Phenylalanine; Tryptophan; Tyrosine | 2000 |
Peroxynitrite does not decompose to singlet oxygen ((1)Delta (g)O(2)) andnitroxyl (NO(-)).
Topics: Chromatography, High Pressure Liquid; Mass Spectrometry; Nitrates; Nitrogen Oxides; Oxygen; Singlet Oxygen | 2000 |
Biphasic regulation of leukocyte superoxide generation by nitric oxide and peroxynitrite.
Topics: Blotting, Western; DNA-Binding Proteins; Dose-Response Relationship, Drug; Electron Spin Resonance Spectroscopy; Enzyme Activation; Enzyme Inhibitors; Ferric Compounds; Flavonoids; Humans; Inflammation; Metalloporphyrins; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; NADPH Oxidases; Nerve Tissue Proteins; Neutrophils; Nitrates; Nitric Oxide; Oxygen; Phosphorylation; Receptors, Steroid; Receptors, Thyroid Hormone; Spin Trapping; Superoxides; Tetradecanoylphorbol Acetate; Time Factors | 2000 |
Importance of guanine nitration and hydroxylation in DNA in vitro and in vivo.
Topics: Animals; Cattle; DNA; Escherichia coli; Guanine; Humans; Hydrogen Peroxide; In Vitro Techniques; Lipopolysaccharides; Liver; Lymphocytes; Male; Mice; Mice, Inbred Strains; Neutrophils; Nitrates; Nitrosation; Oxidants; Peroxidase; Tetradecanoylphorbol Acetate | 2000 |
Chromium (VI) increases endothelial cell expression of ICAM-1 and decreases nitric oxide activity.
Topics: Cells, Cultured; Endothelium, Vascular; Free Radicals; Humans; Intercellular Adhesion Molecule-1; Nitrates; Nitric Oxide; Nitrites; Potassium Dichromate; RNA, Messenger; Superoxides; Tyrosine | 2000 |
Nitric oxide can differentially modulate striatal neurotransmitter concentrations via soluble guanylate cyclase and peroxynitrite formation.
Topics: Animals; Calcium; Corpus Striatum; Cyclic GMP; Dopamine; Dose-Response Relationship, Drug; Free Radical Scavengers; Guanylate Cyclase; Male; Microdialysis; Neurotransmitter Agents; Nitrates; Nitric Oxide; Nitric Oxide Donors; Rats; Rats, Wistar | 2000 |
Evidence for peroxynitrite formation in renal ischemia-reperfusion injury: studies with the inducible nitric oxide synthase inhibitor L-N(6)-(1-Iminoethyl)lysine.
Topics: Animals; Enzyme Inhibitors; Ischemia; Kidney; Lysine; Male; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Rats; Rats, Sprague-Dawley; Reperfusion Injury | 2000 |
Tanshinone II-A inhibits low density lipoprotein oxidation in vitro.
Topics: Abietanes; Copper; Drugs, Chinese Herbal; Free Radical Scavengers; Humans; Lipoproteins, LDL; Macrophages; Nitrates; Oxidation-Reduction; Peroxides; Phenanthrenes; Superoxides; Thiobarbituric Acid Reactive Substances | 2000 |
Effects of homocysteine on endothelial nitric oxide production.
Topics: Animals; Arginine; Bradykinin; Calcimycin; Cells, Cultured; Endothelium, Vascular; Folic Acid; Free Radical Scavengers; Homocysteine; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Rats; Reactive Oxygen Species; Recombinant Proteins; Superoxides; Tyrosine | 2000 |
Protection of myelin basic protein immunized mice from free-radical mediated inflammatory cell invasion of the central nervous system by the natural peroxynitrite scavenger uric acid.
Topics: Animals; Blood-Brain Barrier; Disease Models, Animal; Encephalomyelitis, Autoimmune, Experimental; Female; Free Radicals; Gene Expression Regulation, Enzymologic; Immunization; Lipid Peroxidation; Mice; Mice, Inbred Strains; Monocytes; Multiple Sclerosis; Myelin Basic Protein; Nitrates; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; RNA, Messenger; Uric Acid | 2000 |
Involvement of mitogen-activated protein kinase in peroxynitrite-induced cell death of human neuroblastoma SH-SY5Y cells.
Topics: Cell Survival; Enzyme Inhibitors; Flavonoids; Humans; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Neuroblastoma; Nitrates; Oxidants; Tumor Cells, Cultured | 2000 |
Adaptive responses to peroxynitrite: increased glutathione levels and cystine uptake in vascular cells.
Topics: Adaptation, Physiological; Animals; Cattle; Cells, Cultured; Cystine; Dose-Response Relationship, Drug; Endothelium, Vascular; Free Radical Scavengers; Glutamic Acid; Glutathione; Metalloporphyrins; Molsidomine; Muscle, Smooth, Vascular; Nitrates; Nitric Oxide Donors; Nucleic Acid Synthesis Inhibitors; Penicillamine; Protein Synthesis Inhibitors; S-Nitroso-N-Acetylpenicillamine; Sodium; Superoxide Dismutase | 2000 |
Reversal of nitric oxide-, peroxynitrite- and S-nitrosothiol-induced inhibition of mitochondrial respiration or complex I activity by light and thiols.
Topics: Animals; Cell Line; Cell Respiration; Electron Transport Complex I; Energy Metabolism; Enzyme Activation; Light; Macrophages; Mercaptoethanol; Mice; Mitochondria, Heart; NADH, NADPH Oxidoreductases; Nitrates; Nitric Oxide; Nitroso Compounds; Oxygen Consumption; Rats; S-Nitrosothiols; Sulfhydryl Compounds | 2000 |
Lipid peroxidation and peroxynitrite in retinal ischemia-reperfusion injury.
Topics: Aldehydes; Animals; Cell Death; Cyclin D1; Fluorescent Antibody Technique, Indirect; Free Radical Scavengers; Lipid Peroxidation; Lipid Peroxides; Male; Nitrates; Propidium; Proto-Oncogene Proteins c-jun; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Reperfusion Injury; Retina; Retinal Diseases; Thiobarbituric Acid Reactive Substances; Thioredoxins | 2000 |
cGMP-independent inotropic effects of nitric oxide and peroxynitrite donors: potential role for nitrosylation.
Topics: Animals; Cyclic GMP; Diethylamines; Drug Combinations; Enzyme Inhibitors; Glutathione; In Vitro Techniques; Male; Molsidomine; Myocardial Contraction; Nitrates; Nitric Oxide; Nitric Oxide Donors; Nitroprusside; Nucleotides, Cyclic; Oxadiazoles; Oxidation-Reduction; Quinoxalines; Rats; Rats, Wistar; Superoxide Dismutase | 2000 |
Suppression of the development of hypertension by the inhibitor of inducible nitric oxide synthase.
Topics: Animals; Aorta; Blood Pressure; Disease Models, Animal; Enzyme Inhibitors; Guanidines; Hypertension; Immunoassay; Male; Nitrates; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Proline; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Superoxides; Thiocarbamates; Tyrosine; Vasodilation | 2000 |
The use of seldi proteinchip arrays to monitor production of Alzheimer's betaamyloid in transfected cells.
Topics: Alzheimer Disease; Amino Acid Sequence; Amyloid beta-Peptides; Amyloid Precursor Protein Secretases; Aspartic Acid Endopeptidases; Cells, Cultured; Endopeptidases; Humans; Kidney; Mass Spectrometry; Molecular Sequence Data; Nitrates; Oligonucleotide Array Sequence Analysis; Oxidants; Peptide Fragments; Transfection | 2000 |
Effects of hepatocellular iron imbalance on nitric oxide and reactive oxygen intermediates production in a model of sepsis.
Topics: Animals; Glutathione; Gram-Positive Bacterial Infections; Hepatitis, Viral, Animal; Hydroxyl Radical; Iron; Iron-Regulatory Proteins; Iron-Sulfur Proteins; Liver; Male; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; Nitro Compounds; Propionibacterium acnes; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; RNA-Binding Proteins; Sulfhydryl Compounds; Superoxides | 2000 |
Application of chemically induced dynamic nuclear polarization to the nitration of N-acetyltyrosine and to some reactions of peroxynitrite.
Topics: Absorption; Free Radicals; Hydrogen-Ion Concentration; Kinetics; Magnetic Resonance Spectroscopy; Molecular Structure; Nitrates; Nitric Acid; Nitrites; Nitrobenzenes; Nitrogen Isotopes; Tyrosine | 2000 |
Overexpression of neutrophil neuronal nitric oxide synthase in Parkinson's disease.
Topics: Blotting, Western; Enzyme Induction; Female; Humans; Hydrogen Peroxide; Male; Middle Aged; Neutrophils; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Parkinson Disease; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Spectrophotometry; Tyrosine | 2000 |
Effects of lidocaine on rabbit isolated thoracic aorta.
Topics: Animals; Anti-Arrhythmia Agents; Aorta, Thoracic; Dose-Response Relationship, Drug; Drug Interactions; Endothelium, Vascular; Female; Lidocaine; Nitrates; Nitroprusside; Rabbits; Vasodilation; Vasodilator Agents | 2000 |
Nitric oxide inhibits isoproterenol-stimulated adipocyte lipolysis through oxidative inactivation of the beta-agonist.
Topics: 3T3 Cells; Adipocytes; Animals; Catecholamines; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Female; Hydrazines; Indolequinones; Indoles; Isoproterenol; Lipolysis; Mice; Molsidomine; Nitrates; Nitric Oxide; Nitric Oxide Donors; Nitrogen Oxides; Oxygen; Rats; Rats, Wistar; Signal Transduction; Spectrophotometry; Time Factors; Tumor Necrosis Factor-alpha; Ultraviolet Rays | 2000 |
Nitric oxide-dependent modification of the sarcoplasmic reticulum Ca-ATPase: localization of cysteine target sites.
Topics: Animals; Calcium-Transporting ATPases; Chromatography, High Pressure Liquid; Cysteine; Enzyme Inhibitors; Free Radicals; Mass Spectrometry; Muscle Contraction; Nitrates; Nitric Oxide; Oxidants; Peptide Mapping; Rabbits; Sarcoplasmic Reticulum; Sulfhydryl Reagents | 2000 |
The role of reactive nitrogen species in secondary spinal cord injury: formation of nitric oxide, peroxynitrite, and nitrated protein.
Topics: Amino Acids; Animals; Immunohistochemistry; Male; Models, Biological; Nitrates; Nitric Oxide; Nitroarginine; Proteins; Rats; Rats, Sprague-Dawley; Spinal Cord; Spinal Cord Injuries; Superoxide Dismutase; Tyrosine; Wounds, Nonpenetrating | 2000 |
Nitrosation of melatonin by nitric oxide and peroxynitrite.
Topics: Antioxidants; Chromatography, High Pressure Liquid; Melatonin; Nitrates; Nitric Oxide; Nitrosation; Oxidation-Reduction | 2000 |
Peroxynitrite formed by mitochondrial NO synthase promotes mitochondrial Ca2+ release.
Topics: Animals; Calcium; Feedback; Female; Free Radical Scavengers; Free Radicals; Homeostasis; Membrane Potentials; Metalloporphyrins; Mitochondria, Liver; NAD; Nitrates; Nitric Oxide Synthase; omega-N-Methylarginine; Oxidants; Oxidation-Reduction; Rats; Rats, Wistar; Rotenone; tert-Butylhydroperoxide | 2000 |
Reactions of peroxynitrite in the mitochondrial matrix.
Topics: Animals; Ascorbic Acid; Blotting, Western; Carbon Dioxide; Glutathione; Inhibitory Concentration 50; Kinetics; Mice; Mitochondria, Liver; NAD; Nitrates; Oxidation-Reduction; Spectrometry, Fluorescence; Superoxides; Tyrosine; Ubiquinone | 2000 |
Metallothionein inhibits peroxynitrite-induced DNA and lipoprotein damage.
Topics: Antioxidants; Cell-Free System; DNA Damage; Dose-Response Relationship, Drug; Lipid Peroxides; Lipoproteins; Lipoproteins, LDL; Metallothionein; Molsidomine; Nitrates; Nitrogen; Oxygen; Plasmids; Temperature; Thiobarbituric Acid Reactive Substances; Time Factors | 2000 |
Dopamine-melanin protects against tyrosine nitration, tryptophan oxidation and Ca(2+)-ATPase inactivation induced by peroxynitrite.
Topics: Animals; Antioxidants; Calcium-Transporting ATPases; Cattle; Erythrocyte Membrane; Humans; Kinetics; Melanins; Nitrates; Oxidants; Oxidation-Reduction; Serum Albumin, Bovine; Tryptophan; Tyrosine | 2000 |
Role of nitric oxide and superoxide in acute cardiac allograft rejection in rats.
Topics: Acute Disease; Animals; Electron Spin Resonance Spectroscopy; Graft Rejection; Heart Transplantation; In Vitro Techniques; Male; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; omega-N-Methylarginine; Perfusion; Rats; Rats, Inbred ACI; Rats, Inbred Lew; Superoxide Dismutase; Superoxides; Transplantation, Homologous; Tyrosine | 2000 |
Role of inducible nitric-oxide synthase in regulation of whole-cell current in lung epithelial cells.
Topics: Cyclic GMP; Cytokines; Enzyme Activation; Glutathione; Humans; Interferon-gamma; Interleukin-1; Ion Channels; Lung; Membrane Potentials; Nitrates; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Nitroso Compounds; Patch-Clamp Techniques; Recombinant Proteins; S-Nitrosoglutathione; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 2000 |
Autocatalytic nitration of P450CAM by peroxynitrite.
Topics: Binding Sites; Blotting, Western; Camphor 5-Monooxygenase; Carbon Monoxide; Catalysis; Cytochrome P-450 Enzyme System; Heme; Hydroxylation; Intramolecular Oxidoreductases; Kinetics; Ligands; Mass Spectrometry; Models, Molecular; Nitrates; Nitrogen; Phenol; Protein Binding; Protein Conformation; Protons; Spectrophotometry; Time Factors; Tyrosine | 2000 |
Nitric oxide and superoxide anion in low-grade esophagitis induced by acid and pepsin in rabbits.
Topics: Animals; Enzyme Inhibitors; Esophagitis; Esophagus; Free Radicals; Mucous Membrane; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Nitroprusside; Oxidants; Pepsin A; Rabbits; Superoxide Dismutase; Superoxides | 2000 |
Hypercapnia induces injury to alveolar epithelial cells via a nitric oxide-dependent pathway.
Topics: Animals; Apoptosis; Carbon Dioxide; Cells, Cultured; Cytokines; Fetus; Hypercapnia; Interferon-gamma; Interleukin-1; Lipopolysaccharides; Nitrates; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Pulmonary Alveoli; Rats; Respiratory Mucosa; Tumor Necrosis Factor-alpha; Tyrosine | 2000 |
BCL-2 protects peroxynitrite-treated thymocytes from poly(ADP-ribose) synthase (PARS)-independent apoptotic but not from PARS-mediated necrotic cell death.
Topics: Animals; Apoptosis; Caspases; DNA Fragmentation; Enzyme Activation; Genes, bcl-2; In Vitro Techniques; Mice; Mice, Transgenic; Mitochondria; Necrosis; Nitrates; Poly(ADP-ribose) Polymerases; Proto-Oncogene Proteins c-bcl-2; T-Lymphocytes; Transglutaminases | 2000 |
Products of the phospholipase A(2) pathway mediate the dihydrorhodamine fluorescence response evoked by endogenous and exogenous peroxynitrite in PC12 cells.
Topics: Animals; Arachidonic Acid; Enzyme Activation; Enzyme Inhibitors; Fluorescent Dyes; Microscopy, Confocal; Nitrates; Oxidants; PC12 Cells; Phospholipases A; Rats; Reactive Oxygen Species; Rhodamines; tert-Butylhydroperoxide | 2000 |
Peroxynitrite activates the phosphoinositide 3-kinase/Akt pathway in human skin primary fibroblasts.
Topics: Androstadienes; Apoptosis; Blotting, Western; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Chromones; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Fibroblasts; Glycogen Synthase Kinase 3; Glycogen Synthase Kinases; Humans; Molsidomine; Morpholines; Nitrates; Oxidative Stress; Phosphatidylinositol 3-Kinases; Phosphorylation; Precipitin Tests; Protein Isoforms; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Receptors, Platelet-Derived Growth Factor; Signal Transduction; Skin; Time Factors; Tyrosine; Tyrphostins; Wortmannin | 2000 |
Effects of propofol on endothelial cells subjected to a peroxynitrite donor (SIN-1).
Topics: Anesthetics, Intravenous; Cell Culture Techniques; Cell Death; Dose-Response Relationship, Drug; Endothelium, Vascular; Humans; Molsidomine; Nitrates; Nitric Oxide Donors; Propofol; Tyrosine | 2000 |
Inducible nitric oxide synthase-knockout mice exhibit resistance to pleurisy and lung injury caused by carrageenan.
Topics: Animals; Carrageenan; Cells, Cultured; DNA Damage; Enzyme Activation; Exudates and Transudates; Immunohistochemistry; Lipid Peroxidation; Lung; Macrophages; Male; Malondialdehyde; Mice; Mice, Knockout; Neutrophils; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Peroxidase; Pleura; Pleurisy; Poly(ADP-ribose) Polymerases; Tyrosine | 2000 |
Peroxynitrite formation and decreased catalase activity in autoimmune MRL-lpr/lpr mice.
Topics: Animals; Arthritis; Autoimmune Diseases; Catalase; Cattle; DNA Damage; Glomerulonephritis; Immunoblotting; Kidney; Liver; Mice; Mice, Inbred MRL lpr; Mice, Knockout; Molsidomine; Nitrates; Nitric Oxide Donors; omega-N-Methylarginine; Oxidative Stress; Reactive Oxygen Species; Superoxide Dismutase | 2000 |
Nitric oxide inhibits tyrosine hydroxylase of rat median eminence.
Topics: Animals; Dose-Response Relationship, Drug; Enzyme Inhibitors; Free Radical Scavengers; Guanylate Cyclase; Hemoglobins; Male; Median Eminence; Methylene Blue; Nitrates; Nitric Oxide; Nitric Oxide Donors; Nitroprusside; Rats; Rats, Sprague-Dawley; Superoxide Dismutase; Superoxides; Tyrosine 3-Monooxygenase; Uric Acid | 2000 |
Peroxynitrite attenuates hepatic ischemia-reperfusion injury.
Topics: Alanine Transaminase; Animals; Antisense Elements (Genetics); Cell Adhesion; Gene Expression; Intercellular Adhesion Molecule-1; Leukocytes; Liver; Male; Nitrates; Oxidants; P-Selectin; Rats; Rats, Inbred F344; Reperfusion Injury; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Stroke Volume | 2000 |
Mechanism for the peroxynitrite scavenging activity by anthocyanins.
Topics: Anthocyanins; Chromatography, High Pressure Liquid; Free Radical Scavengers; Kinetics; Nitrates; Nitrobenzoates; Oxidants; Parabens; Tyrosine | 2000 |
Radical dinitroalkane dianions from the nitration of nitroalkanes by peroxynitrite.
Topics: Electron Spin Resonance Spectroscopy; Free Radicals; Nitrates; Nitroparaffins | 2000 |
Amperometric ultramicrosensors for peroxynitrite detection and its application toward single myocardial cells.
Topics: Animals; Animals, Newborn; Calibration; Cells, Cultured; Electrochemistry; Melatonin; Microchemistry; Myocardial Reperfusion Injury; Myocardium; Nitrates; Oxidants; Rats; Sensitivity and Specificity | 2000 |
Nitration and inactivation of cytochrome P450BM-3 by peroxynitrite. Stopped-flow measurements prove ferryl intermediates.
Topics: Animals; Bacillus; Bacterial Proteins; Binding Sites; Blotting, Western; Cattle; Chromatography, High Pressure Liquid; Cytochrome P-450 Enzyme System; Dithiothreitol; Dose-Response Relationship, Drug; Erythrocytes; Glutathione; Inhibitory Concentration 50; Iron; Mass Spectrometry; Mixed Function Oxygenases; Models, Chemical; Models, Molecular; Molsidomine; NADPH-Ferrihemoprotein Reductase; Nitrates; Nitric Oxide Donors; Nitrogen; Oxygen; Superoxide Dismutase; Temperature; Time Factors; Tyrosine; Uric Acid | 2000 |
Glutathione reverses endothelial damage from peroxynitrite, the byproduct of nitric oxide degradation, in crystalloid cardioplegia.
Topics: Animals; Bicarbonates; Calcium Chloride; Cardiopulmonary Bypass; Cell Adhesion; Coronary Vessels; Creatine Kinase; Dogs; Endothelium, Vascular; Female; Glutathione; Heart; Heart Arrest, Induced; Hemodynamics; Hypothermia, Induced; In Vitro Techniques; Magnesium; Male; Myocardial Reperfusion; Myocardium; Neutrophils; Nitrates; Nitric Oxide; Nitroso Compounds; Peroxidase; Potassium Chloride; S-Nitrosoglutathione; Sodium Chloride; Ventricular Function, Left | 2000 |
The peroxynitrite scavenger uric acid prevents inflammatory cell invasion into the central nervous system in experimental allergic encephalomyelitis through maintenance of blood-central nervous system barrier integrity.
Topics: Animals; Blood-Brain Barrier; Capillary Permeability; Cell Movement; Central Nervous System; Encephalomyelitis, Autoimmune, Experimental; Female; Free Radical Scavengers; Injections, Intraperitoneal; Injections, Subcutaneous; Macrophages, Peritoneal; Mice; Mice, Inbred Strains; Myelin Basic Protein; Nitrates; Oxidation-Reduction; Uric Acid | 2000 |
Inflammatory properties of IgG modified by oxygen radicals and peroxynitrite.
Topics: Acute Disease; Animals; Arthritis, Experimental; Arthritis, Rheumatoid; Binding Sites, Antibody; Complement C1q; Complement C3; Female; Free Radicals; Gout; Humans; Hydrogen Peroxide; Hypochlorous Acid; Immunoglobulin G; Male; Neutrophils; Nitrates; Osteoarthritis; Oxidation-Reduction; Oxygen; Rabbits; Receptors, IgG; Serum Albumin, Bovine; Synovial Fluid; Tyrosine | 2000 |
Permeation of phospholipid membranes by peroxynitrite.
Topics: Diffusion; Ferricyanides; Kinetics; Lipid Peroxidation; Liposomes; Malondialdehyde; Mathematical Computing; Models, Chemical; Nitrates; Oxidants; Oxidation-Reduction; Permeability; Phosphatidylcholines; Phospholipids; Thiobarbituric Acid Reactive Substances | 2000 |
Protection against nitric oxide toxicity by tea.
Topics: Animals; Cell Line; Enzyme Induction; Flavonoids; Lipopolysaccharides; Macrophages, Alveolar; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; Phenols; Phytotherapy; Polymers; Polyphenols; Rats; Tea; Wine | 2000 |
Nitric oxide activation of TrkB through peroxynitrite.
Topics: 3T3 Cells; Animals; Brain-Derived Neurotrophic Factor; Carbazoles; Humans; Indole Alkaloids; Isoenzymes; Mice; Molsidomine; Nitrates; Nitric Oxide; Nitric Oxide Donors; Oxidants; Phospholipase C gamma; Phosphorylation; Phosphotyrosine; Rats; Receptor, trkB; Recombinant Proteins; Superoxide Dismutase; Transfection; Type C Phospholipases | 2000 |
GnRH agonist-suppressed expression of nitric oxide synthases and generation of peroxynitrite in adenomyosis.
Topics: Adult; Endometriosis; Endometrium; Epithelial Cells; Female; Follicular Phase; Gonadotropin-Releasing Hormone; Humans; Luteal Phase; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Nitrites; Stromal Cells; Tyrosine | 2000 |
Peroxynitrite induces integrin-dependent adhesion of human neutrophils to endothelial cells via activation of the Raf-1/MEK/Erk pathway.
Topics: CD18 Antigens; Cell Adhesion; Cells, Cultured; Coronary Vessels; E-Selectin; Endothelium, Vascular; Enzyme Activation; Flavonoids; Humans; Integrins; Intercellular Adhesion Molecule-1; L-Selectin; Lipopolysaccharides; Macrophage-1 Antigen; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Models, Biological; Neutrophils; Nitrates; p38 Mitogen-Activated Protein Kinases; Proto-Oncogene Proteins c-raf; Proto-Oncogene Proteins p21(ras) | 2001 |
Peroxynitrite-induced modification of the N-methyl-D-aspartate receptor in the cerebral cortex of the guinea pig fetus at term.
Topics: Animals; Cerebral Cortex; Dizocilpine Maleate; Fetus; Glutamic Acid; Guinea Pigs; Hypoxia; Ion Channels; Kinetics; Nitrates; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate | 2000 |
The modulation of oxygen radical production by nitric oxide in mitochondria.
Topics: Animals; Arginine; Cytochrome b Group; Dose-Response Relationship, Drug; Electron Transport; Electron Transport Complex IV; Enzyme Inhibitors; Free Radicals; Glutathione; Hydrogen Peroxide; Mitochondria, Liver; Models, Chemical; Myoglobin; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitroso Compounds; omega-N-Methylarginine; Oxygen; Oxygen Consumption; Rats; Rats, Wistar; S-Nitrosoglutathione | 2001 |
Antioxidant actions of ovothiol-derived 4-mercaptoimidazoles: glutathione peroxidase activity and protection against peroxynitrite-induced damage.
Topics: Antioxidants; Azoles; Catalysis; Chromans; Evans Blue; Free Radical Scavengers; Glutathione; Glutathione Peroxidase; Hydrogen Peroxide; Imidazoles; Inhibitory Concentration 50; Isoindoles; Kinetics; Methylhistidines; NADP; Nitrates; Organoselenium Compounds; Oxidants; Oxidation-Reduction; Rhodamines; Sulfhydryl Compounds | 2000 |
Augmented death in immunostimulated astrocytes deprived of glucose: inhibition by an iron porphyrin FeTMPyP.
Topics: Animals; Astrocytes; Cell Death; Ferric Compounds; Glucose; Interferon-gamma; Membrane Potentials; Metalloporphyrins; Mitochondria; Molsidomine; Nitrates; Porphyrins; Rats; Rats, Sprague-Dawley | 2001 |
Cyclosporin-induced endothelial dysfunction and hypertension: are nitric oxide system abnormality and oxidative stress involved?
Topics: Adult; Cyclosporine; Endothelium, Vascular; Female; Humans; Hypertension; Immunosuppressive Agents; Kidney Transplantation; Lipid Peroxides; Male; Middle Aged; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Nitrogen Oxides; Oxidants; Oxidative Stress; Reverse Transcriptase Polymerase Chain Reaction | 2000 |
Muscular contractile failure in septic patients: role of the inducible nitric oxide synthase pathway.
Topics: Adult; Aged; Base Sequence; Biopsy; Female; Humans; Immunohistochemistry; Male; Middle Aged; Molecular Sequence Data; Muscle Contraction; Nitrates; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Oxidants; Rectus Abdominis; Sepsis | 2000 |
A reevaluation of the peroxynitrite scavenging activity of some dietary phenolics.
Topics: alpha 1-Antitrypsin; Bicarbonates; Caffeic Acids; Chlorogenic Acid; Coumaric Acids; Diet; Free Radical Scavengers; Gallic Acid; Kinetics; Nitrates; Oxidants; Pancreatic Elastase; Phenols; Structure-Activity Relationship; Tyrosine | 2000 |
Peroxynitrite formation in the orbit of diabetics with rhinocerebral mucormycosis.
Topics: Adolescent; Adult; Aged; Brain Diseases; Diabetes Mellitus; Eye Infections, Fungal; Female; Humans; Immunoenzyme Techniques; Male; Middle Aged; Mucormycosis; Nitrates; Orbital Diseases; Paranasal Sinus Diseases; Respiratory Burst; Tyrosine | 2000 |
Enhanced peroxynitrite formation is associated with vascular aging.
Topics: Acetylcholine; Aging; Animals; Aorta; Body Weight; Calcimycin; Cellular Senescence; Endothelium, Vascular; Enzyme Induction; Hemodynamics; Male; Microscopy, Immunoelectron; Mitochondria; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; Oxidative Stress; Rats; Rats, Inbred Strains; Superoxide Dismutase; Superoxides; Tyrosine; Vasodilation | 2000 |
LC-MS/MS detection of peroxynitrite-derived 3-nitrotyrosine in rat microvessels.
Topics: Animals; Brain; Chromatography, Liquid; Mass Spectrometry; Microcirculation; Microscopy, Phase-Contrast; Nitrates; Rats; Rats, Wistar; Sensitivity and Specificity; Tyrosine | 2000 |
A novel procedure for generating both nitric oxide and superoxide in situ from chemical sources at any chosen mole ratio. First application: tyrosine oxidation and a comparison with preformed peroxynitrite.
Topics: Molsidomine; Nitrates; Nitric Oxide; Nitric Oxide Donors; Nitrogen Oxides; Oxidants; Oxidation-Reduction; Spermine; Superoxides; Tyrosine | 2000 |
Peroxynitrite produces relaxations on the rat anococcygeus muscle.
Topics: Animals; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth; Nitrates; Rats | 2000 |
The role of uric acid in protection against peroxynitrite-mediated pathology.
Topics: Animals; Humans; Mice; Monocytes; Nitrates; Uric Acid | 2001 |
Carbon dioxide stimulates the production of thiyl, sulfinyl, and disulfide radical anion from thiol oxidation by peroxynitrite.
Topics: Albumins; Anions; Carbon Dioxide; Cysteine; Disulfides; Dose-Response Relationship, Drug; Electron Spin Resonance Spectroscopy; Electrons; Glutathione; Hydrogen-Ion Concentration; Models, Chemical; Nitrates; Oxygen; Spin Trapping; Sulfhydryl Compounds; Temperature | 2001 |
Reactive oxygen and nitrogen metabolites modulate fibronectin-induced fibroblast migration in vitro.
Topics: Blood; Cell Line; Cell Movement; Complement Activation; Deferoxamine; Dithiothreitol; Embryo, Mammalian; Fibroblasts; Fibronectins; Humans; Lung; Molsidomine; Nitrates; Nitric Oxide Donors; Nitrogen; Reactive Oxygen Species; Reducing Agents; Superoxides; Tyrosine; Xanthine Oxidase | 2001 |
Synergistic effects of peroxynitrite on arecoline-induced cytotoxicity in human buccal mucosal fibroblasts.
Topics: Arecoline; Cells, Cultured; Cholinergic Agents; Dose-Response Relationship, Drug; Drug Synergism; Fibroblasts; Glutathione; Humans; Kinetics; Mouth Mucosa; Nitrates; Oxidants | 2000 |
Essential role of the mitochondrial respiratory chain in peroxynitrite-induced strand scission of genomic DNA.
Topics: DNA Damage; Electron Transport; Humans; Hydrogen Peroxide; Kinetics; Methacrylates; Mitochondria; Nitrates; Oxygen Consumption; Potassium Cyanide; Rotenone; Thiazoles; U937 Cells | 2000 |
Toxicity of nitric oxide and peroxynitrite to bacterial pathogens of fish.
Topics: Aeromonas; Animals; Bacterial Infections; Catalase; Cell-Free System; Fish Diseases; Free Radical Scavengers; Microbial Sensitivity Tests; Molsidomine; Nitrates; Nitric Oxide; Nitric Oxide Donors; Oncorhynchus mykiss; Oxidants; Penicillamine; S-Nitroso-N-Acetylpenicillamine; Superoxide Dismutase | 2000 |
Purines inhibit poly(ADP-ribose) polymerase activation and modulate oxidant-induced cell death.
Topics: Animals; Cardiolipins; Caspase 3; Caspases; Cell Death; Cell Line; Cell Respiration; Cell Survival; Cells, Cultured; Cytochrome c Group; Cytoprotection; DNA Fragmentation; Enzyme Activation; Flow Cytometry; Hypoxanthine; Macrophage Activation; Macrophages; Male; Membrane Potentials; Mice; Mitochondria; Necrosis; Nitrates; Nitric Oxide; Oxidants; Poly(ADP-ribose) Polymerases; Purines; Superoxides; Thymus Gland | 2001 |
Reaction of peroxynitrite with Mn-superoxide dismutase. Role of the metal center in decomposition kinetics and nitration.
Topics: Binding Sites; Humans; Kinetics; Metals; Nitrates; Recombinant Proteins; Spectrometry, Mass, Electrospray Ionization; Superoxide Dismutase; Zinc | 2001 |
Protective effects of a new stable, highly active SOD mimetic, M40401 in splanchnic artery occlusion and reperfusion.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arterial Occlusive Diseases; Catalysis; Cytokines; Fluorescent Antibody Technique; Ileum; Leukocyte Count; Male; Malondialdehyde; Manganese; Nitrates; Nitrites; Organometallic Compounds; P-Selectin; Peroxidase; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Splanchnic Circulation; Superoxide Dismutase; Superoxides; Tyrosine | 2001 |
Peroxynitrite: toxic or protective in the heart?
Topics: Animals; Cell Adhesion; Crystalloid Solutions; Cytoprotection; Dogs; Heart; Humans; In Vitro Techniques; Injections, Intravenous; Isotonic Solutions; Mice; Myocardial Contraction; Myocardium; Nitrates; Nitric Oxide; Oxidative Stress; Plasma Substitutes; Rats; Reperfusion Injury; Sulfhydryl Compounds | 2001 |
Peroxynitrite plays a role in methamphetamine-induced dopaminergic neurotoxicity: evidence from mice lacking neuronal nitric oxide synthase gene or overexpressing copper-zinc superoxide dismutase.
Topics: Animals; Central Nervous System Stimulants; Corpus Striatum; Dopamine; Dopamine Uptake Inhibitors; Methamphetamine; Mice; Mice, Inbred C57BL; Mice, Knockout; Neurotoxins; Nitrates; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Reference Values; Superoxide Dismutase; Tyrosine | 2001 |
Adenovirus infection increases iNOS and peroxynitrite production in the lung.
Topics: Adenoviridae Infections; Animals; Blotting, Western; Bronchoalveolar Lavage Fluid; Female; Immunohistochemistry; Lung; Male; Mice; Mice, Inbred BALB C; Nitrates; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Pulmonary Surfactants; Tyrosine | 2001 |
Lipopolysaccharide binding protein potentiates airway reactivity in a murine model of allergic asthma.
Topics: Acute-Phase Proteins; Adjuvants, Immunologic; Aerosols; Allergens; Animals; Asthma; Bronchial Hyperreactivity; Carrier Proteins; Disease Models, Animal; Immunoglobulin E; Immunoglobulin G; Inflammation; Injections, Intraperitoneal; Lipopolysaccharides; Lung; Membrane Glycoproteins; Mice; Mice, Inbred BALB C; Mice, Knockout; Nitrates; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Ovalbumin | 2001 |
Peroxynitrite induces GADD34, 45, and 153 VIA p38 MAPK in human neuroblastoma SH-SY5Y cells.
Topics: Antigens, Differentiation; Antioxidants; Apoptosis; CCAAT-Enhancer-Binding Proteins; Cell Cycle Proteins; DNA Damage; Enzyme Activation; Flow Cytometry; GADD45 Proteins; Gene Expression Regulation, Neoplastic; Glutathione; Humans; Imidazoles; Intracellular Signaling Peptides and Proteins; Microscopy, Fluorescence; Mitogen-Activated Protein Kinases; Molsidomine; Neoplasm Proteins; Neuroblastoma; Nitrates; Oxidation-Reduction; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Protein Phosphatase 1; Protein Serine-Threonine Kinases; Proteins; Pyridines; RNA, Messenger; Signal Transduction; Transcription Factor CHOP; Transcription Factors; Tumor Cells, Cultured | 2001 |
Inhibition of nerve growth factor signaling by peroxynitrite.
Topics: Acetylcholine; Alzheimer Disease; Animals; Brain; Cell Survival; Dose-Response Relationship, Drug; Humans; MAP Kinase Signaling System; Molsidomine; Nerve Growth Factor; Neurons; Nitrates; Nitric Oxide Donors; Oxidative Stress; PC12 Cells; Rats; Receptor, trkA | 2001 |
Analysis of the effects of cell spacing and liquid depth on nitric oxide and its oxidation products in cell cultures.
Topics: Animals; Cell Adhesion; Cell Count; Cell Culture Techniques; Culture Media; Diffusion; Macrophages; Models, Biological; Nitrates; Nitric Oxide; Nitrites; Nitrogen Oxides; Oxidation-Reduction; Superoxides | 2001 |
Antioxidative properties of phenolic antioxidants isolated from corn steep liquor.
Topics: Acetates; Animals; Antioxidants; Ascorbic Acid; Chromatography, High Pressure Liquid; Coumaric Acids; Erythrocyte Membrane; Fermentation; Lipoproteins; Magnetic Resonance Spectroscopy; Nitrates; Phenols; Rabbits; Tyrosine; Vitamin E; Zea mays | 2001 |
The stable nitroxide, tempol, attenuates the effects of peroxynitrite and oxygen-derived free radicals.
Topics: Animals; Cyclic N-Oxides; Free Radical Scavengers; Hydroxyl Radical; Nitrates; Rats; Spin Labels | 2001 |
Nitric oxide generation by hemocytes of the mussel Mytilus galloprovincialis.
Topics: Animals; Arginine; Bivalvia; Citrulline; Enzyme Inhibitors; Hemocytes; Latex; Luminescent Measurements; Microspheres; NADPH Oxidases; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; omega-N-Methylarginine; Ornithine; Phagocytosis; Superoxide Dismutase; Superoxides | 2001 |
Oxidation of adrenaline and its derivatives by S-nitrosoglutathione.
Topics: Adrenochrome; Copper; Epinephrine; Glutathione; Hydrogen-Ion Concentration; Indoles; Isomerism; Nitrates; Nitric Oxide; Nitroso Compounds; Oxidants; Oxidation-Reduction; Oxygen; S-Nitrosoglutathione; Spectrophotometry; Superoxides | 2001 |
Pharmacological manipulation of the inflammatory cascade by the superoxide dismutase mimetic, M40403.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cytokines; Dinoprostone; DNA Damage; Intercellular Adhesion Molecule-1; Macrophages; Male; Manganese; Nitrates; Organometallic Compounds; P-Selectin; Pleurisy; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Sprague-Dawley; Superoxides | 2001 |
Prospects for the treatment of multiple sclerosis by raising serum levels of uric acid, a scavenger of peroxynitrite.
Topics: Humans; Multiple Sclerosis; Nitrates; Oxidants; Time Factors; Uric Acid | 2001 |
In vitro study of the antioxidant properties of non steroidal anti-inflammatory drugs by chemiluminescence and electron spin resonance (ESR).
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Ascorbic Acid; Chlorine; Diclofenac; Electron Spin Resonance Spectroscopy; Free Radicals; Humans; In Vitro Techniques; Indicators and Reagents; Indomethacin; Iron; Kinetics; Lipid Peroxidation; Luminescent Measurements; Neutrophil Activation; Neutrophils; Nitrates; Reactive Oxygen Species; Sodium Hypochlorite; Spectrophotometry, Ultraviolet; Sulfonamides; Tetradecanoylphorbol Acetate | 2000 |
Aging-related expression of inducible nitric oxide synthase and markers of tissue damage in the rat penis.
Topics: Aging; Animals; Apoptosis; Blotting, Northern; Blotting, Western; Collagen; Cysteine Endopeptidases; DNA Fragmentation; Gene Expression Regulation, Enzymologic; Image Processing, Computer-Assisted; In Situ Nick-End Labeling; Male; Multienzyme Complexes; Muscle, Smooth; Nitrates; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Penis; Proteasome Endopeptidase Complex; Rats; Rats, Inbred F344; Reverse Transcriptase Polymerase Chain Reaction; RNA; RNA, Messenger; Tyrosine; Ubiquitins | 2001 |
Pressure dependence of peroxynitrite reactions. Support for a radical mechanism.
Topics: Cyanides; Free Radicals; Hydrogen-Ion Concentration; Indicators and Reagents; Kinetics; Nitrates; Oxidation-Reduction; Pressure | 2001 |
Superoxide reactivates nitric oxide-inhibited catalase.
Topics: Animals; Binding, Competitive; Catalase; Cattle; Enzyme Reactivators; Hydrogen Peroxide; Kinetics; Liver; Nitrates; Nitric Oxide; Oxidants; Superoxide Dismutase; Superoxides | 2000 |
Characterization of peroxynitrite-oxidized low density lipoprotein binding to human CD36.
Topics: Animals; Arteriosclerosis; CD36 Antigens; CHO Cells; Copper; Cricetinae; Electrophoresis, Agar Gel; Electrophoresis, Polyacrylamide Gel; Erythrocytes; Humans; Lipid Peroxides; Lipoproteins, LDL; Membrane Proteins; Molsidomine; Nitrates; Oxidation-Reduction; Plasmodium falciparum; Receptors, Immunologic; Receptors, Lipoprotein; Receptors, Scavenger; Scavenger Receptors, Class B; Thiobarbituric Acid Reactive Substances; Transfection | 2001 |
Sodium nitroprusside-induced seizures and adenosine release in rat hippocampus.
Topics: Adenosine; Animals; Aspartic Acid; Chelating Agents; Dithiothreitol; Ditiocarb; Hippocampus; Male; Nitrates; Nitric Oxide; Nitric Oxide Donors; Nitroprusside; Rats; Rats, Wistar; Seizures; Vasodilator Agents | 2001 |
Endogenous and new synthetic antioxidants for peroxynitrite: selective inhibitory effect of 5-methoxytryptamine and lipoic acid on tyrosine nitration by peroxynitrite.
Topics: 5-Methoxytryptamine; Antioxidants; Chromatography, High Pressure Liquid; Dopamine Agents; Levodopa; Nitrates; Oxidants; Oxidation-Reduction; Proline; Pyrrolidines; Thioctic Acid; Tyrosine | 1999 |
Peroxynitrite induced nitration and inactivation of myofibrillar creatine kinase in experimental heart failure.
Topics: Animals; Creatine Kinase; Creatine Kinase, MM Form; Heart Failure; Image Processing, Computer-Assisted; Immunohistochemistry; Isoenzymes; Male; Myofibrils; Myosins; Nitrates; Oxidants; Rats; Rats, Sprague-Dawley; Tyrosine | 2001 |
Endothelial regulation of vasomotion in apoE-deficient mice: implications for interactions between peroxynitrite and tetrahydrobiopterin.
Topics: Acetylcholine; Animals; Aorta, Thoracic; Apolipoproteins E; Biopterins; Calcimycin; Dose-Response Relationship, Drug; Endothelium, Vascular; Female; In Vitro Techniques; Ionophores; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Nitrates; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Nitroglycerin; Pteridines; Pterins; Superoxides; Vasodilation; Vasodilator Agents | 2001 |
Motor neurons rapidly accumulate DNA single-strand breaks after in vitro exposure to nitric oxide and peroxynitrite and in vivo axotomy.
Topics: Animals; Apoptosis; Cell Survival; Cells, Cultured; Comet Assay; DNA; DNA Damage; Functional Laterality; Hydrogen Peroxide; Male; Models, Neurological; Motor Neurons; Nitrates; Nitric Oxide Donors; Nitroprusside; Oxidative Stress; Rats; Rats, Sprague-Dawley; Sciatic Nerve; Spinal Cord; Superoxides | 2001 |
Ca2+ mediates the effect of inhibition of Na+-K+-ATPase on the basolateral K+ channels in the rat CCD.
Topics: Animals; Benzylamines; Biological Transport; Calcium; Calcium-Calmodulin-Dependent Protein Kinases; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Ion Channel Gating; Ionomycin; Ionophores; Kidney Tubules, Collecting; Male; Membrane Potentials; Naphthalenes; NG-Nitroarginine Methyl Ester; Nitrates; Potassium Channels; Protein Kinase C; Rats; Rats, Sprague-Dawley; Sodium-Potassium-Exchanging ATPase; Specific Pathogen-Free Organisms; Strophanthidin; Sulfonamides; Superoxides | 2001 |
Peroxynitrite inhibits the activity of ornithine decarboxylase.
Topics: Animals; Blotting, Western; Cell Line; Dose-Response Relationship, Drug; Enzyme Inhibitors; Epithelial Cells; Nitrates; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Oxidants; Rats; Recombinant Proteins; Tyrosine | 2001 |
DNA integrity and total oxyradical scavenging capacity in the Mediterranean mussel, Mytilus galloprovincialis: a field study in a highly eutrophicated coastal lagoon.
Topics: Animals; Bivalvia; DNA; DNA Damage; Eutrophication; Free Radical Scavengers; Free Radicals; Italy; Nitrates; Oxidative Stress; Reactive Oxygen Species | 2001 |
Kinetic and mechanistic studies of the NO*-mediated oxidation of oxymyoglobin and oxyhemoglobin.
Topics: Animals; Chromatography, High Pressure Liquid; Horses; Humans; Hydrogen-Ion Concentration; Kinetics; Ligands; Metmyoglobin; Myoglobin; Nitrates; Nitric Oxide; Nitrogen Dioxide; Oxidation-Reduction; Oxyhemoglobins; Spectrophotometry, Ultraviolet; Spectrum Analysis | 2001 |
Tamoxifen inhibits nitrotyrosine formation after reversible middle cerebral artery occlusion in the rat.
Topics: Animals; Brain; Cerebral Cortex; Disease Models, Animal; Enzyme Inhibitors; Indazoles; Ischemic Attack, Transient; Male; Middle Cerebral Artery; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Rats; Rats, Sprague-Dawley; Reference Values; Superoxides; Tamoxifen; Tyrosine | 2001 |
Intravasal peroxynitrite generation causes dysfunction in the isolated perfused rat lung via endothelin.
Topics: Animals; Bronchoconstriction; Endothelins; Female; Lung; Nitrates; Oligopeptides; Peptides, Cyclic; Perfusion; Piperidines; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Wistar; Vasoconstriction | 2001 |
Flavonoids as peroxynitrite scavengers: the role of the hydroxyl groups.
Topics: Catechols; Flavonoids; Hydroxides; Nitrates; Oxidants; Structure-Activity Relationship | 2001 |
Chemical evaluation of compounds as nitric oxide or peroxynitrite donors using the reactions with serotonin.
Topics: Aerobiosis; Chromatography, High Pressure Liquid; Copper; Glutathione; Molsidomine; Nitrates; Nitric Oxide; Nitric Oxide Donors; Nitro Compounds; Nitroprusside; Nitroso Compounds; Oxidants; Oxidation-Reduction; S-Nitrosoglutathione; Serotonin; Tyrosine | 2001 |
Acidic fibroblast growth factor attenuates the cytotoxic effects of peroxynitrite in primary human osteoblast precursors.
Topics: Apoptosis; Cell Differentiation; Cell Division; Cells, Cultured; Cytotoxicity, Immunologic; Drug Evaluation, Preclinical; Fibroblast Growth Factor 1; Fracture Healing; Fractures, Bone; Humans; Inflammation; Neovascularization, Physiologic; Nitrates; Osteocalcin; Osteogenesis; Osteopontin; Oxidants; Reactive Oxygen Species; Sialoglycoproteins; Stem Cells; Stromal Cells | 2001 |
Effect of peroxynitrite on motor function of the opossum esophagus.
Topics: Animals; Enzyme Inhibitors; Esophagitis; Esophagogastric Junction; Female; Guanylate Cyclase; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth; Nitrates; Opossums; Oxadiazoles; Oxidants; Oxyhemoglobins; Quinoxalines; Tyrosine | 2001 |
Protective effects of morphine in peroxynitrite-induced apoptosis of primary rat neonatal astrocytes: potential involvement of G protein and phosphatidylinositol 3-kinase (PI3 kinase).
Topics: Animals; Apoptosis; Astrocytes; Cell Survival; Cells, Cultured; Chromatin; DNA Fragmentation; Drug Interactions; Female; Glutathione; GTP-Binding Proteins; Molsidomine; Morphine; Naloxone; Narcotic Antagonists; Nitrates; Nitric Oxide Donors; Oxidants; Phosphatidylinositol 3-Kinases; Protective Agents; Rats; Rats, Sprague-Dawley | 2001 |
Contribution of peroxynitrite to the beneficial effects of preconditioning on ischaemia-induced arrhythmias in rat isolated hearts.
Topics: Animals; Arrhythmias, Cardiac; Heart; Ischemic Preconditioning, Myocardial; Male; Myocardial Reperfusion; Nitrates; Oxidants; Rats; Rats, Wistar; Uric Acid | 2001 |
Different kinds of reactive oxygen and nitrogen species were detected in colon and breast tumors.
Topics: Acridines; Adult; Aged; Breast Neoplasms; Colonic Neoplasms; Female; Humans; Hypochlorous Acid; Luminescent Measurements; Luminol; Male; Middle Aged; Nitrates; Nitric Oxide; Reactive Oxygen Species | 2001 |
Cytotoxic effects of peroxynitrite, polymorphonuclear neutrophils, free-radical scavengers, inhibitors of myeloperoxidase, and inhibitors of nitric oxide synthase on bovine mammary secretory epithelial cells.
Topics: Aniline Compounds; Animals; Antioxidants; Blotting, Western; Cattle; Cell Death; Enzyme Inhibitors; Epithelial Cells; Female; Free Radical Scavengers; Histidine; L-Lactate Dehydrogenase; Lipopolysaccharides; Mammary Glands, Animal; Molsidomine; Neutrophil Activation; Neutrophils; Nitrates; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Oxidants; Peroxidase; Superoxide Dismutase; Tetradecanoylphorbol Acetate; Tyrosine | 2001 |
Spiroiminodihydantoin is the major product of the 8-oxo-7,8-dihydroguanosine reaction with peroxynitrite in the presence of thiols and guanosine photooxidation by methylene blue.
Topics: Chromatography, High Pressure Liquid; Guanosine; Methylene Blue; Molecular Structure; Nitrates; Oxidants; Oxidation-Reduction; Spiro Compounds; Sulfhydryl Compounds | 2001 |
Inhibition of oxidized low-density lipoprotein-induced apoptosis in endothelial cells by nitric oxide. Peroxyl radical scavenging as an antiapoptotic mechanism.
Topics: Animals; Antioxidants; Aorta; Apoptosis; Caspase 3; Caspases; Catalase; Cattle; Cell Membrane Permeability; Cells, Cultured; DNA Fragmentation; Endothelium, Vascular; Enzyme Activation; Glutathione Peroxidase; HSP70 Heat-Shock Proteins; In Situ Nick-End Labeling; Iron Chelating Agents; Kinetics; Lipoproteins, LDL; Models, Biological; Nitrates; Nitric Oxide; Nitric Oxide Donors; Oxidants; Proto-Oncogene Proteins c-bcl-2; Superoxide Dismutase | 2001 |
Inhibition of peroxynitrite-induced dityrosine formation with oxidized and reduced thiols, nitric oxide donors, and purine derivatives.
Topics: Molecular Structure; Nitrates; Nitric Oxide; Nitric Oxide Donors; Oxidative Stress; Purines; Sulfhydryl Compounds; Tyrosine; Uric Acid | 2001 |
Identification of respiratory complexes I and III as mitochondrial sites of damage following exposure to ionizing radiation and nitric oxide.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Apoptosis; Cattle; Cell Line; Electron Spin Resonance Spectroscopy; Electron Transport; Half-Life; Hematopoietic Stem Cells; Intracellular Membranes; Mitochondria; NADH Dehydrogenase; Nitrates; Nitric Oxide; Oxidants; Oxidative Stress; Rabbits; Radiation, Ionizing; Superoxide Dismutase; Superoxides | 2001 |
Protection of primary glial cells by grape seed proanthocyanidin extract against nitrosative/oxidative stress.
Topics: Animals; Anthocyanins; Antioxidants; Cells, Cultured; Glutathione; Hydrogen Peroxide; Immunohistochemistry; Interferon-gamma; Lipopolysaccharides; Macrophages; Mice; Microscopy, Fluorescence; Neuroglia; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrosation; Oxidants; Oxidative Stress; Plant Extracts; Proanthocyanidins; Rats; Rats, Wistar; Rosales; Seeds; tert-Butylhydroperoxide | 2001 |
Nitric oxide and peroxynitrite in postischemic myocardium.
Topics: Animals; Electron Spin Resonance Spectroscopy; Enzyme Inhibitors; Female; Immunoenzyme Techniques; Myocardial Contraction; Myocardial Ischemia; Myocardial Reperfusion Injury; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Oxidants; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Superoxide Dismutase | 2001 |
Failure to sustain recovery of Na,K-ATPase function is a possible mechanism for striatal neurodegeneration in hypoxic-ischemic newborn piglets.
Topics: Animals; Animals, Newborn; Cell Death; Cerebral Palsy; Enzyme Activation; Hypoxia-Ischemia, Brain; Neostriatum; Nerve Degeneration; Neurons; Neurotoxins; Nitrates; Nitric Oxide; Oxidative Stress; Sodium-Potassium-Exchanging ATPase; Swine | 2001 |
SIN-1-induced DNA damage in isolated human peripheral blood lymphocytes as assessed by single cell gel electrophoresis (comet assay).
Topics: Ascorbic Acid; Calcium; Catalase; Chelating Agents; Comet Assay; Data Interpretation, Statistical; DNA Damage; DNA, Single-Stranded; Dose-Response Relationship, Drug; Egtazic Acid; Flow Cytometry; Humans; Kinetics; Lymphocytes; Microscopy, Ultraviolet; Molsidomine; Nitrates; Nitric Oxide Donors; Superoxide Dismutase | 2001 |
Antioxidant capacity of mononitrosyl-iron-dithiocarbamate complexes: implications for NO trapping.
Topics: Air; Antioxidants; Ascorbic Acid; Cell Line; Cerium; Dimerization; Electron Spin Resonance Spectroscopy; Endothelium, Vascular; Ferrous Compounds; Kinetics; Ligands; Nitrates; Nitric Oxide; Oxidants; Sorbitol; Spin Labels; Spin Trapping; Superoxide Dismutase; Superoxides; Thiocarbamates | 2001 |
Peroxynitrite reduces vasodilatory responses to reduced intravascular pressure, calcitonin gene-related peptide, and cromakalim in isolated middle cerebral arteries.
Topics: Animals; Calcitonin Gene-Related Peptide; Cromakalim; Free Radicals; Hypotension; Male; Middle Cerebral Artery; Nitrates; Nitric Oxide; Oxidants; Potassium Channels; Rats; Rats, Sprague-Dawley; Vasodilation; Vasodilator Agents | 2001 |
Inhibition of caspase-3 activation by SB 203580, p38 mitogen-activated protein kinase inhibitor in nitric oxide-induced apoptosis of PC-12 cells.
Topics: Animals; Apoptosis; Caspase 3; Caspases; Cell Survival; Enzyme Inhibitors; Imidazoles; Mitogen-Activated Protein Kinase 8; Mitogen-Activated Protein Kinase 9; Mitogen-Activated Protein Kinases; Nitrates; Nitric Oxide; Nitric Oxide Donors; p38 Mitogen-Activated Protein Kinases; PC12 Cells; Pyridines; Rats | 2000 |
Gibbs energy of formation of peroxynitrite.
Topics: Chromatography, Liquid; Kinetics; Nitrates; Spectrophotometry, Ultraviolet; Thermodynamics | 2001 |
Analysis of peroxynitrite reactions with guanine, xanthine, and adenine nucleosides by high-pressure liquid chromatography with electrochemical detection: C8-nitration and -oxidation.
Topics: Adenine; Chromatography, High Pressure Liquid; Electrochemistry; Guanine; Nitrates; Oxidation-Reduction; Purine Nucleosides; Xanthine | 2001 |
Nitric oxide synthase II gene disruption: implications for tumor growth and vascular endothelial growth factor production.
Topics: Animals; Cell Division; Endothelial Growth Factors; Female; Immunohistochemistry; Lymphokines; Male; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Mice, Knockout; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; RNA, Messenger; Serotonin; Tumor Cells, Cultured; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors | 2001 |
Effects of urate, a natural inhibitor of peroxynitrite-mediated toxicity, in the response of Arabidopsis thaliana to the bacterial pathogen Pseudomonas syringae.
Topics: Arabidopsis; Arabidopsis Proteins; Blotting, Northern; Cell Death; Nitrates; Nitric Oxide; Nitric Oxide Donors; Nitroprusside; Peroxidases; Plant Proteins; Pseudomonas; RNA, Plant; Uric Acid; Virulence; Xanthomonas campestris | 2001 |
Eosinophils are a major source of nitric oxide-derived oxidants in severe asthma: characterization of pathways available to eosinophils for generating reactive nitrogen species.
Topics: Eosinophil Peroxidase; Eosinophils; Free Radicals; Humans; Immunohistochemistry; Nitrates; Nitric Oxide; Nitric Oxide Donors; Nitrites; Oxidants; Oxidation-Reduction; Peroxidases; Phenylpropionates; Proteins; Reactive Oxygen Species; Status Asthmaticus; Tyrosine | 2001 |
A redox-based mechanism for the contractile and relaxing effects of NO in the guinea-pig gall bladder.
Topics: Acetylcholine; Animals; Arachidonic Acid; Atropine; Calcium; Gallbladder; Guinea Pigs; Male; Molsidomine; Muscle Contraction; Muscle, Smooth; Nitrates; Nitric Oxide; Nitric Oxide Donors; Nitroprusside; Nitroso Compounds; Oxidants; Oxidation-Reduction; Parasympatholytics; Vasodilator Agents | 2001 |
Parasiticidal effects of peroxynitrite on ovine liver flukes in vitro.
Topics: Animals; Dicrocoelium; Dose-Response Relationship, Drug; Fasciola hepatica; In Vitro Techniques; Liver; Nitrates; Oxidants; Sheep | 2001 |
Acidic fibroblast growth factor (FGF-1) signaling inhibits peroxynitrite-induced cell death during pancreatic tumorigenesis.
Topics: Animals; Cell Death; Cell Line; Fibroblast Growth Factor 1; Fibroblast Growth Factor 2; Free Radicals; Humans; Nitrates; Pancreatic Neoplasms; Rats; RNA, Messenger; Signal Transduction; Transduction, Genetic | 2001 |
Peroxynitrite inhibits inducible (type 2) nitric oxide synthase in murine lung epithelial cells in vitro.
Topics: Animals; Base Sequence; Cell Line; DNA Primers; Enzyme Inhibitors; Epithelial Cells; Gene Expression; Hydrazines; Lung; Mice; Molsidomine; Nitrates; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Oxidants; RNA, Messenger; Tyrosine | 2001 |
Hepatocellular oxidative DNA injury induced by macrophage-derived nitric oxide.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Deoxyguanosine; DNA Damage; Enzyme Inhibitors; Free Radicals; Hepatocytes; In Vitro Techniques; Interferon-gamma; Lipopolysaccharides; Macrophages; Male; Molsidomine; Nitrates; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Oxidation-Reduction; Rats; Rats, Wistar; Recombinant Proteins; Superoxide Dismutase | 2001 |
Apolipoprotein A-I promotes the formation of phosphatidylcholine core aldehydes that are hydrolyzed by paraoxonase (PON-1) during high density lipoprotein oxidation with a peroxynitrite donor.
Topics: Aldehydes; Apolipoprotein A-I; Aryldialkylphosphatase; Electrophoresis, Polyacrylamide Gel; Esterases; Humans; Hydrolysis; Lipoproteins, HDL; Lysophosphatidylcholines; Molsidomine; Nitrates; Oxidation-Reduction; Phosphatidylcholines; Phospholipases A; Proteolipids; Trypsin | 2001 |
Peroxynitrite leads to arteriolar smooth muscle cell membrane hyperpolarization and low vasoreactivity in severe shock.
Topics: 1,2-Dihydroxybenzene-3,5-Disulfonic Acid Disodium Salt; Animals; Arginine; Arterioles; Charybdotoxin; Cyclic GMP; Drug Interactions; Female; Free Radical Scavengers; Glyburide; Guanidines; Ion Transport; Male; Membrane Potentials; Mesenteric Arteries; Microscopy, Confocal; Microscopy, Fluorescence; Muscle, Smooth, Vascular; Nitrates; Nitric Oxide Donors; Norepinephrine; Oxadiazoles; Penicillamine; Potassium; Potassium Channels; Quinoxalines; Rats; Rats, Sprague-Dawley; Shock, Hemorrhagic; Vasodilator Agents | 2000 |
Cyclooxygenase-2 protein and prostaglandin E(2) production are up-regulated in a rat bladder inflammation model.
Topics: Administration, Intravesical; Animals; Blotting, Western; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Female; Inflammation; Injections, Intraperitoneal; Isoenzymes; Lipopolysaccharides; Membrane Proteins; Niflumic Acid; Nitrates; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Oxidants; Penicillamine; Prostaglandin-Endoperoxide Synthases; Protamines; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Up-Regulation; Urinary Bladder | 2001 |
Protective effects of n-acetylcysteine on lung injury and red blood cell modification induced by carrageenan in the rat.
Topics: Acetylcysteine; Animals; Blotting, Western; Carrageenan; Disease Models, Animal; DNA Damage; DNA-Binding Proteins; Erythrocytes; Free Radical Scavengers; I-kappa B Proteins; Immunohistochemistry; Intercellular Adhesion Molecule-1; Lung; Macrophages; Male; Malondialdehyde; Neutrophils; NF-KappaB Inhibitor alpha; Nitrates; Nitric Oxide; P-Selectin; Peroxidase; Pleurisy; Poly(ADP-ribose) Polymerases; Rats; Rats, Sprague-Dawley; Tyrosine | 2001 |
Formation of peroxynitrite in vascular endothelial cells exposed to cyclosporine A.
Topics: Animals; Aorta; Cattle; Cells, Cultured; Cyclic N-Oxides; Cyclosporine; Endothelium, Vascular; Enzyme Inhibitors; Flow Cytometry; Fluorescent Dyes; Free Radical Scavengers; Humans; Immunosuppressive Agents; Models, Biological; Naphthoquinones; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Oxidants; Spin Trapping; Superoxide Dismutase; Superoxides | 2001 |
Enhanced vascular permeability in solid tumor involving peroxynitrite and matrix metalloproteinases.
Topics: Adenocarcinoma; Animals; Azoles; Bradykinin; Capillary Permeability; Collagenases; Colonic Neoplasms; Dose-Response Relationship, Drug; Enzyme Precursors; Free Radical Scavengers; Gelatinases; Guinea Pigs; Isoindoles; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Matrix Metalloproteinase Inhibitors; Metalloendopeptidases; Mice; Mice, Inbred C57BL; Nitrates; Oligopeptides; Organoselenium Compounds; Protease Inhibitors; Sarcoma 180; Skin; Tyrosine; Uric Acid | 2001 |
Effect of peroxynitrite on dormant spores and germlings of Aspergillus fumigatus in vitro.
Topics: Animals; Aspergillosis; Aspergillus fumigatus; Chickens; Dose-Response Relationship, Drug; Humans; Nitrates; Nitric Oxide Donors; Oxidants; Spores, Fungal; Time Factors | 2000 |
Nitrogen dioxide induces death in lung epithelial cells in a density-dependent manner.
Topics: Cell Count; Cell Death; Cells, Cultured; Culture Media, Conditioned; DNA, Single-Stranded; In Situ Nick-End Labeling; Lung; Molsidomine; Nitrates; Nitric Oxide Donors; Nitrites; Nitrogen Dioxide; Oxidative Stress; Respiratory Mucosa | 2001 |
Central and ambivalent role of hydrogen peroxide during intercellular induction of apoptosis.
Topics: Apoptosis; Cell Line, Transformed; Cells, Cultured; Coculture Techniques; Fibroblasts; Hydrogen Peroxide; Hydroxyl Radical; Nitrates; Nitric Oxide; Reactive Oxygen Species; Signal Transduction; Transforming Growth Factor beta | 2001 |
iNOS upregulation mediates oxidant-induced disruption of F-actin and barrier of intestinal monolayers.
Topics: Actins; Caco-2 Cells; Cytoskeleton; Humans; Hydrogen Peroxide; Intestinal Mucosa; Intestines; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Oxidants; Oxidative Stress; Permeability; Up-Regulation | 2001 |
Coronary and myocardial effects of acetaminophen: protection during ischemia-reperfusion.
Topics: Acetaminophen; Animals; Coronary Circulation; Coronary Vessels; Cytoprotection; Dose-Response Relationship, Drug; Female; Gentisates; Guinea Pigs; Heart; Heart Rate; Hydroxybenzoates; Hydroxyl Radical; In Vitro Techniques; Luminescent Measurements; Male; Myocardial Ischemia; Myocardial Reperfusion; Myocardial Reperfusion Injury; Myocardium; Myofibrils; Nitrates; Perfusion; Vasoconstriction; Ventricular Function, Left | 2001 |
Free radical production in aortic rings from rats fed a fish oil-rich diet.
Topics: Acetylcholine; Administration, Oral; Animals; Aorta; Body Weight; Dietary Fats, Unsaturated; Dose-Response Relationship, Drug; Fish Oils; Food, Formulated; Free Radicals; In Vitro Techniques; Male; Nitrates; Nitroprusside; Phenylephrine; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Sprague-Dawley; Superoxide Dismutase; Superoxides; Vasoconstriction; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents | 2001 |
Colon epithelial cell death in 2,4,6-trinitrobenzenesulfonic acid-induced colitis is associated with increased inducible nitric-oxide synthase expression and peroxynitrite production.
Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Cell Death; Colitis; Colon; Disease Models, Animal; Epithelial Cells; Immunohistochemistry; In Situ Nick-End Labeling; Isoenzymes; Lysine; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Peroxidase; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley; Superoxides; Trinitrobenzenesulfonic Acid; Tyrosine | 2001 |
Artifactual-free analysis of S-nitrosoglutathione and S-nitroglutathione by neutral-pH, anion-pairing, high-performance liquid chromatography. Study on peroxynitrite-mediated S-nitration of glutathione to S-nitroglutathione under physiological conditions.
Topics: Anions; Artifacts; Chromatography, High Pressure Liquid; Glutathione; Hydrogen-Ion Concentration; Nitrates; Nitro Compounds; Nitroso Compounds; S-Nitrosoglutathione; Spectrophotometry, Ultraviolet | 2001 |
Peroxynitrite mediates cytokine-induced IL-8 gene expression and production by human leukocytes.
Topics: Antioxidants; Cell Nucleus; Cells, Cultured; Gene Expression; Guanidines; Humans; Interleukin-1; Interleukin-8; Leukocytes, Mononuclear; NF-kappa B; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide Synthase; Pyrrolidines; RNA, Messenger; Thiocarbamates; Transcription Factor AP-1; Tumor Necrosis Factor-alpha | 2001 |
Nitric oxide and Coxsackievirus B3 myocarditis: differential expression of inducible nitric oxide synthase in mouse heart after infection with virulent or attenuated virus.
Topics: Animals; Disease Models, Animal; Enterovirus; Guanosine Monophosphate; Heart; Immunohistochemistry; Male; Mice; Myocarditis; Myocardium; Nitrates; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nucleic Acid Hybridization; RNA, Viral; Tyrosine | 2001 |
In vitro generation of peroxynitrite by 2- and 4-hydroxyestrogens in the presence of nitric oxide.
Topics: Chromatography, High Pressure Liquid; Estradiol; Estrogens, Catechol; Hydroxyestrones; Mass Spectrometry; Nitrates; Nitric Oxide | 2001 |
One- and two-electron oxidation reactions of trolox by peroxynitrite.
Topics: Benzoquinones; Chromans; Chromatography, High Pressure Liquid; Electron Transport; Kinetics; Nitrates; Nitriles; Oxidation-Reduction; Spectrophotometry; Vitamin E | 2001 |
Intracellular ascorbic acid enhances the DNA single-strand breakage and toxicity induced by peroxynitrite in U937 cells.
Topics: Ascorbic Acid; Dehydroascorbic Acid; DNA Damage; Ferricyanides; Free Radical Scavengers; Humans; Iron Chelating Agents; Nitrates; Oxidation-Reduction; U937 Cells | 2001 |
Involvement of enhanced sensitivity of N-methyl-D-aspartate receptors in vulnerability of developing cortical neurons to methylmercury neurotoxicity.
Topics: Age Factors; Animals; Animals, Newborn; Antigens, CD; Antigens, Neoplasm; Antigens, Surface; Avian Proteins; Basigin; Blood Proteins; Cerebral Cortex; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glutamic Acid; Membrane Glycoproteins; Mercury Poisoning, Nervous System; Methylmercury Compounds; Nerve Degeneration; Neurons; Nitrates; Quinoxalines; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Tyrosine | 2001 |
Peroxynitrite-dependent activation of src tyrosine kinases lyn and hck in erythrocytes is under mechanistically different pathways of redox control.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Alkylation; Cysteine; Diffusion; Dithiothreitol; Enzyme Activation; Erythrocytes; Ethylmaleimide; Glucose; Humans; Hydrogen Peroxide; Immunochemistry; Nitrates; Oxidation-Reduction; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-hck; Sequence Homology; Signal Transduction; Sodium Bicarbonate; src-Family Kinases; Substrate Specificity | 2001 |
In vivo and in vitro apoptosis of human thymocytes are associated with nitrotyrosine formation.
Topics: Annexin A5; Apoptosis; Cells, Cultured; Child, Preschool; Enzyme Inhibitors; Epithelial Cells; Gene Expression; Humans; In Situ Nick-End Labeling; Molsidomine; Nitrates; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Stromal Cells; Superoxide Dismutase; Superoxides; T-Lymphocytes; Thymus Gland; Tyrosine | 2001 |
Mechanisms of peroxynitrite decomposition catalyzed by FeTMPS, a bioactive sulfonated iron porphyrin.
Topics: Catalysis; Computer Simulation; Ferric Compounds; Hydrogen Peroxide; Kinetics; Metalloporphyrins; Models, Chemical; Nitrates; Nitric Oxide; Nitrites; Oxidation-Reduction; Spectrophotometry | 2001 |
Site-selective nitration of tyrosine in human serum albumin by peroxynitrite.
Topics: Binding Sites; Chemical Phenomena; Chemistry; Chromatography, High Pressure Liquid; Humans; Mass Spectrometry; Molecular Structure; Nitrates; Peptides; Serum Albumin; Tyrosine | 2001 |
Reaction of superoxide and nitric oxide with peroxynitrite. Implications for peroxynitrite-mediated oxidation reactions in vivo.
Topics: Catalase; Glutathione; Humans; Hypoxanthine; Kinetics; NAD; Nitrates; Nitric Oxide; Nitrogen Oxides; Oxidation-Reduction; Pteridines; Recombinant Proteins; Rhodamines; Spermine; Superoxide Dismutase; Superoxides; Xanthine Oxidase | 2001 |
Nitric oxide measurements during endotoxemia.
Topics: Animals; Endotoxemia; Male; Nitrates; Nitric Oxide; Rats; Rats, Inbred WKY; Superoxides | 2001 |
Oxidative stress promotes the development of transformation: involvement of a potent mutagenic lipid peroxidation product, acrolein.
Topics: Acrolein; Amidines; Animals; Antioxidants; Benzo(a)pyrene; Biotransformation; Cell Transformation, Neoplastic; Fibroblasts; Free Radicals; Lipid Peroxidation; Mice; Mice, Inbred C3H; Molsidomine; Mutagens; Nitrates; Nitric Oxide Donors; Oxidants; Oxidative Stress; Reactive Oxygen Species; Vitamin E | 2001 |
Peroxynitrite decay in the presence of hydrogen peroxide, mannitol and ethanol: a reappraisal.
Topics: Biophysics; Ethanol; Hydrogen Peroxide; Mannitol; Nitrates; Superoxide Dismutase; Superoxides | 2001 |
Peroxynitrite promotes mitochondrial permeability transition-dependent rapid U937 cell necrosis: survivors proliferate with kinetics superimposable on those of untreated cells.
Topics: Antioxidants; Cell Division; Cell Survival; Chromans; Cyclosporine; Dose-Response Relationship, Drug; Humans; Intracellular Membranes; Kinetics; Methionine; Mitochondria; Necrosis; Nitrates; Permeability; U937 Cells | 2001 |
Immunostimulation of rat primary astrocytes decreases intracellular ATP level.
Topics: Adenosine Triphosphate; Animals; Animals, Newborn; Astrocytes; Central Nervous System; Dose-Response Relationship, Drug; Encephalitis; Enzyme Inhibitors; Inflammation Mediators; Interferon-gamma; Intracellular Fluid; L-Lactate Dehydrogenase; Lipopolysaccharides; Molsidomine; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Penicillamine; Rats; Rats, Sprague-Dawley; S-Nitroso-N-Acetylpenicillamine; Tumor Cells, Cultured | 2001 |
Two different NO-dependent mechanisms account for the low virulence of a non-mycelial morphological mutant of Candida albicans.
Topics: Animals; Candida albicans; Candidiasis; Guanidines; Macrophages, Peritoneal; Mice; Mice, Inbred BALB C; Molsidomine; Mutagenesis; Nitrates; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; Virulence | 2001 |
Activation of matrix metalloproteinases by peroxynitrite-induced protein S-glutathiolation via disulfide S-oxide formation.
Topics: Amino Acid Sequence; Binding Sites; Collagenases; Disulfides; Enzyme Activation; Enzyme Precursors; Glutathione; Humans; Kinetics; Matrix Metalloproteinase 9; Matrix Metalloproteinases; Nitrates; Nitroso Compounds; Oxidation-Reduction; Peptide Fragments; Protein Processing, Post-Translational; S-Nitrosoglutathione; Serum Albumin, Bovine; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Sulfur Radioisotopes; Tritium | 2001 |
DNA damage by nitrite and peroxynitrite: protection by dietary phenols.
Topics: Animals; Cattle; Chromatography, High Pressure Liquid; DNA; DNA Damage; Electrochemistry; Fruit; Gas Chromatography-Mass Spectrometry; Guanine; Nitrates; Nitrites; Phenols; Reference Standards; Spectrophotometry, Ultraviolet; Vegetables | 2001 |
Effects of peroxynitrite on the reactivity of diabetic rat aorta.
Topics: Acetylcholine; Animals; Aorta; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Endothelium, Vascular; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Nitrates; Phenylephrine; Rats; Rats, Wistar; Sodium Nitrite; Vasoconstrictor Agents; Vasodilator Agents | 2001 |
Gibbs energy of formation of peroxynitrite--order restored.
Topics: Kinetics; Nitrates; Nitric Oxide; Nitrogen Dioxide; Oxidants; Thermodynamics | 2001 |
Nitration and oxidation of a hydrophobic tyrosine probe by peroxynitrite in membranes: comparison with nitration and oxidation of tyrosine by peroxynitrite in aqueous solution.
Topics: Bicarbonates; Cyclic N-Oxides; Free Radicals; Hydroxyl Radical; Lipid Bilayers; Liposomes; Mass Spectrometry; Membranes, Artificial; Molsidomine; Nitrates; Nitrosation; Oxidation-Reduction; Solutions; Solvents; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Spin Labels; Tyrosine; Water | 2001 |
Peroxynitrite activates mitogen-activated protein kinase (MAPK) via a MEK-independent pathway: a role for protein kinase C.
Topics: Animals; Calcium; Calcium Signaling; Cell Line; Cell Membrane; Down-Regulation; Enzyme Activation; Fibroblasts; MAP Kinase Kinase 1; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Nitrates; Phorbol 12,13-Dibutyrate; Phosphorylation; Protein Kinase C; Protein Serine-Threonine Kinases; Protein Transport; Rats | 2001 |
UV light synergistically enhances the cardiotoxic effects of interleukin 1beta through peroxynitrite formation.
Topics: Animals; Animals, Newborn; Cardiomyopathies; Drug Synergism; Homeostasis; In Vitro Techniques; Interleukin-1; Microscopy, Video; Myocardial Contraction; Nitrates; Oxidants; Rats; Rats, Sprague-Dawley; Ultraviolet Rays | 2001 |
Protein tyrosine nitration in cytokine-activated murine macrophages. Involvement of a peroxidase/nitrite pathway rather than peroxynitrite.
Topics: Animals; Cell Line; Cytokines; Electrophoresis, Polyacrylamide Gel; Enzyme Inhibitors; Free Radical Scavengers; Hydrogen Peroxide; Immunoblotting; Interferon-gamma; Lipopolysaccharides; Macrophages; Mice; Nitrates; Nitric Oxide; Nitrites; Nitrogen; Oxygen; Peroxidase; Recombinant Proteins; Tetradecanoylphorbol Acetate; Time Factors; Tyrosine; Zymosan | 2001 |
Inhibition of prostaglandin synthesis by nitric oxide in RAW 264.7 macrophages.
Topics: Animals; Arachidonic Acid; Cyclooxygenase 2; Drug Interactions; Isoenzymes; Lipopolysaccharides; Macrophages; Mice; Nitrates; Nitric Oxide; Oxidants; Prostaglandin-Endoperoxide Synthases; Prostaglandins; RNA, Messenger | 2001 |
Peroxynitrite production, DNA breakage, and poly(ADP-ribose) polymerase activation in a mouse model of oxazolone-induced contact hypersensitivity.
Topics: Adjuvants, Immunologic; Animals; Apoptosis; Caspases; Cell Division; Cell Line; Dermatitis, Contact; DNA Damage; DNA Fragmentation; Female; In Situ Nick-End Labeling; Intercellular Adhesion Molecule-1; Interleukin-8; Keratinocytes; Mice; Mice, Inbred Strains; Necrosis; Nitrates; Oxazolone; Poly(ADP-ribose) Polymerases; Skin; Tyrosine | 2001 |
Scavenging of peroxynitrite by phycocyanin and phycocyanobilin from Spirulina platensis: protection against oxidative damage to DNA.
Topics: Cyanobacteria; DNA Damage; DNA, Superhelical; Free Radical Scavengers; Kinetics; Nitrates; Phycobilins; Phycocyanin; Plasmids; Pyrroles; Spectrophotometry; Tetrapyrroles | 2001 |
Myoglobin-catalyzed tyrosine nitration: no need for peroxynitrite.
Topics: Animals; Horses; Hydrogen Peroxide; Hydrogen-Ion Concentration; Kinetics; Metmyoglobin; Myocardium; Myoglobin; Nitrates; Nitrites; Oxidation-Reduction; Tyrosine | 2001 |
Prostaglandins and nitric oxide mediate superoxide-induced myocardial contractile dysfunction in isolated rat hearts.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Aspartate Aminotransferases; Colforsin; Enzyme Inhibitors; Heart; Myocardial Contraction; Myocardium; Nitrates; Nitric Acid; Nitroarginine; Nitroglycerin; Nitroprusside; Oxadiazoles; Phosphodiesterase Inhibitors; Platelet Aggregation Inhibitors; Prostaglandins; Quinoxalines; Rats; Superoxides; Thromboxane A2; Vasodilator Agents | 2001 |
Neutrophils in lung inflammation: Which reactive oxygen species are being measured?
Topics: Adolescent; Adult; Enzyme Inhibitors; Flow Cytometry; Fluoresceins; Humans; Hydrogen Peroxide; Middle Aged; Neutrophils; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Oxidants; Pneumonia; Reactive Oxygen Species; Respiratory Burst; Sulfonamides; Superoxides; Tetradecanoylphorbol Acetate | 2001 |
Modification of a single tryptophan residue in human Cu,Zn-superoxide dismutase by peroxynitrite in the presence of bicarbonate.
Topics: Amino Acids; Bicarbonates; Carbon Dioxide; Copper; Dimerization; Electron Spin Resonance Spectroscopy; Electrophoresis, Polyacrylamide Gel; Humans; Models, Molecular; Nitrates; Recombinant Proteins; Spectrometry, Fluorescence; Superoxide Dismutase; Tryptophan; Zinc | 2001 |
Vascular and hepatocellular peroxynitrite formation during acetaminophen toxicity: role of mitochondrial oxidant stress.
Topics: Acetaminophen; Animals; Blood Vessels; Hepatocytes; Immunohistochemistry; Male; Mice; Mice, Inbred C3H; Mitochondria, Liver; Nitrates; Oxidative Stress | 2001 |
Epicatechin selectively prevents nitration but not oxidation reactions of peroxynitrite.
Topics: Animals; Catechin; Cell-Free System; Cells, Cultured; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Activation; Fluoresceins; Glyceraldehyde-3-Phosphate Dehydrogenases; Lipoxygenase; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Nitrates; Oxidation-Reduction; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Sulfhydryl Compounds; Tyrosine | 2001 |
Inhibition of poly (ADP-ribose) synthetase by gene disruption or inhibition with 5-iodo-6-amino-1,2-benzopyrone protects mice from multiple-low-dose-streptozotocin-induced diabetes.
Topics: Animals; Apoptosis; Blood Glucose; Cell Survival; Coumarins; Cytokines; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Genotype; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Male; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Mice, Knockout; Mutation; Nitrates; Nitric Oxide; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Rats; Severity of Illness Index; Streptozocin; Tumor Cells, Cultured | 2001 |
Peroxynitrite isomerization catalyzed by his64 myoglobin mutants.
Topics: Animals; Isomerism; Mutation; Myoglobin; Nitrates; Spectrophotometry, Ultraviolet; Whales | 2001 |
Common etiology of posttraumatic stress disorder, fibromyalgia, chronic fatigue syndrome and multiple chemical sensitivity via elevated nitric oxide/peroxynitrite.
Topics: Carbon Monoxide; Fatigue Syndrome, Chronic; Fibromyalgia; Humans; Multiple Chemical Sensitivity; Nitrates; Nitric Oxide; Persian Gulf Syndrome; Stress Disorders, Post-Traumatic | 2001 |
Oxidation of active center cysteine of bovine 1-Cys peroxiredoxin to the cysteine sulfenic acid form by peroxide and peroxynitrite.
Topics: Animals; Binding Sites; Cattle; Cysteine; Hydrogen Peroxide; Kinetics; Nitrates; Oxidants; Oxidation-Reduction; Peroxidases; Peroxiredoxins; Recombinant Proteins; Spectrophotometry; Sulfenic Acids; tert-Butylhydroperoxide | 2001 |
The adenine nucleotide translocator: a target of nitric oxide, peroxynitrite, and 4-hydroxynonenal.
Topics: Aldehydes; Animals; Apoptosis; Cell Nucleus; HeLa Cells; Humans; Inhibitor of Apoptosis Proteins; Intracellular Membranes; Ion Channels; Jurkat Cells; Lipid Peroxidation; Membrane Proteins; Mice; Mitochondria; Mitochondrial ADP, ATP Translocases; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Nitrates; Nitric Oxide; Oxidants; Permeability; Proteins; Proteolipids; Proto-Oncogene Proteins c-bcl-2 | 2001 |
Mn(II)-texaphyrin as a catalyst for the decomposition of peroxynitrite.
Topics: Catalysis; Manganese; Nitrates; Oxidants; Porphyrins | 2001 |
Effect of antioxidant treatment of streptozotocin-induced diabetic rats on endoneurial blood flow, motor nerve conduction velocity, and vascular reactivity of epineurial arterioles of the sciatic nerve.
Topics: Animals; Antioxidants; Aorta; Arterioles; Diabetes Mellitus, Experimental; Dietary Supplements; Inositol; Male; Microscopy, Video; Motor Neurons; Muscle, Smooth, Vascular; Neural Conduction; Nitrates; Rats; Rats, Sprague-Dawley; Reference Values; Regional Blood Flow; Sciatic Nerve; Sodium-Potassium-Exchanging ATPase; Sorbitol; Superoxides; Thioctic Acid; Vasodilation | 2001 |
Effects of nitric oxide and peroxynitrite on endotoxin-induced leukocyte adhesion to endothelium.
Topics: Animals; Cattle; Cell Adhesion; Cells, Cultured; Cyclic GMP; Endothelium, Vascular; Enzyme Inhibitors; Interferon-gamma; Leukocytes; Lipopolysaccharides; Molsidomine; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Triazenes | 2001 |
Preconditioning decreases ischemia/reperfusion-induced peroxynitrite formation.
Topics: Animals; Aorta; Blood Flow Velocity; In Vitro Techniques; Ischemic Preconditioning, Myocardial; L-Lactate Dehydrogenase; Male; Myocardial Ischemia; Myocardial Reperfusion; Myocardial Reperfusion Injury; Myocardium; Nitrates; Rats; Rats, Wistar; Time Factors; Tyrosine; Ventricular Function, Left | 2001 |
Peptide methionine sulfoxide reductase from Escherichia coli and Mycobacterium tuberculosis protects bacteria against oxidative damage from reactive nitrogen intermediates.
Topics: Bacterial Proteins; Escherichia coli; Genetic Complementation Test; Glutathione; Macrophages; Methionine; Methionine Sulfoxide Reductases; Mycobacterium tuberculosis; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; Nitroso Compounds; Oxidative Stress; Oxidoreductases; Phenotype; Recombinant Fusion Proteins; S-Nitrosoglutathione | 2001 |
6-hydroxydopamine increases the hydroxylation and nitration of phenylalanine in vivo: implication of peroxynitrite formation.
Topics: Adrenergic Agents; Animals; Chromatography, High Pressure Liquid; Corpus Striatum; Dopamine; Hydroxylation; Male; Microdialysis; Nitrates; Oxidants; Oxidopamine; Phenylalanine; Rats; Rats, Wistar; Time Factors | 2001 |
Neuroprotective and neurorescuing effects of isoform-specific nitric oxide synthase inhibitors, nitric oxide scavenger, and antioxidant against beta-amyloid toxicity.
Topics: Amyloid beta-Peptides; Animals; Antioxidants; Benzoates; Cell Survival; Cells, Cultured; Cerebral Cortex; Chromans; Citrulline; Dose-Response Relationship, Drug; Enzyme Inhibitors; Imidazoles; Isoenzymes; Lysine; Neuroprotective Agents; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Oxidants; Peptide Fragments; Rats; Rats, Sprague-Dawley; Thiourea; Time Factors | 2001 |
Induction of cyclo-oxygenase-2 in human endothelial cells by SIN-1 in the absence of prostaglandin production.
Topics: Blotting, Northern; Blotting, Western; Cell Line; Cyclooxygenase 2; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Inhibitors; Flavonoids; Gene Expression Regulation, Enzymologic; Humans; Imidazoles; Interleukin-1; Isoenzymes; Membrane Proteins; Mitogen-Activated Protein Kinases; Molsidomine; Nitrates; Precipitin Tests; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Pyridines; RNA, Messenger; Time Factors; Tumor Necrosis Factor-alpha | 2001 |
Antioxidant activity of the organotellurium compound 3-[4-(N,N-dimethylamino)benzenetellurenyl]propanesulfonic acid against oxidative stress in synaptosomal membrane systems and neuronal cultures.
Topics: Alkanesulfonic Acids; Animals; Antioxidants; Cell Death; Cell Membrane; Cell Survival; Cells, Cultured; Free Radical Scavengers; Free Radicals; Gerbillinae; Lipid Peroxidation; Luminescent Measurements; Nerve Tissue Proteins; Neurodegenerative Diseases; Neurons; Neuroprotective Agents; Nitrates; Organometallic Compounds; Oxidative Stress; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Synaptosomes; Tellurium | 2001 |
Nitric oxide and peroxynitrite: the balance between cardioprotection and cardiotoxicity.
Topics: Animals; Coronary Circulation; Cytokines; Heart Failure; Heart Rate; Humans; Myocardial Contraction; Nitrates; Nitric Oxide; Rats | 2001 |
Reaction of human myoglobin and peroxynitrite: characterizing biomarkers for myoglobin-derived oxidative stress.
Topics: Biomarkers; Cyclic N-Oxides; Electron Spin Resonance Spectroscopy; Free Radicals; Humans; Molsidomine; Mutagenesis, Site-Directed; Myocardial Reperfusion Injury; Myoglobin; Nitrates; Oxidative Stress; Reactive Oxygen Species | 2001 |
Peroxynitrite causes endothelial cell monolayer barrier dysfunction.
Topics: Actins; Animals; beta Catenin; Cell Survival; Cells, Cultured; Cytoskeletal Proteins; Endothelium, Vascular; Kinetics; Molsidomine; Nitrates; Nitric Oxide; Nitric Oxide Donors; Oxidants; Pulmonary Artery; Reactive Oxygen Species; Superoxide Dismutase; Swine; Trans-Activators; Tyrosine | 2001 |
N-acetyl-L-cysteine improves renal medullary hypoperfusion in acute renal failure.
Topics: Acetylcysteine; Acute Kidney Injury; Animals; Blood Flow Velocity; Disease Models, Animal; Enzyme Inhibitors; Free Radical Scavengers; Glomerular Filtration Rate; Kidney Medulla; Laser-Doppler Flowmetry; NG-Nitroarginine Methyl Ester; Nitrates; Nitrites; Rats; Rats, Wistar; Regional Blood Flow; Reperfusion; Reperfusion Injury; Vena Cava, Inferior | 2001 |
Effects of virgin olive oil phenolics on scavenging of reactive nitrogen species and upon nitrergic neurotransmission.
Topics: Animals; Antioxidants; Caffeic Acids; Dose-Response Relationship, Drug; Free Radical Scavengers; Iridoid Glucosides; Iridoids; Male; Muscle Relaxation; Muscle, Smooth; Neural Conduction; Nitrates; Nitric Oxide; Nitroprusside; Olive Oil; Phenols; Phenylethyl Alcohol; Plant Oils; Pyrans; Rats; Rats, Wistar | 2001 |
-OONO: rebounding from nitric oxide.
Topics: Administration, Inhalation; Animals; Endothelium, Vascular; Epoprostenol; Hemoglobins; Humans; Hydroxyl Radical; Hypertension, Pulmonary; Nitrates; Nitric Oxide; Nitrogen Dioxide; Oxidation-Reduction; Pneumonia; Prostaglandin H2; Prostaglandins H; Signal Transduction; Superoxides; Tyrosine | 2001 |
Role for endothelin-1-induced superoxide and peroxynitrite production in rebound pulmonary hypertension associated with inhaled nitric oxide therapy.
Topics: Administration, Inhalation; Animals; Blotting, Western; Cells, Cultured; Dioxoles; Disease Models, Animal; Endothelin Receptor Antagonists; Endothelin-1; Enzyme Activation; Humans; Hypertension, Pulmonary; Lung; Microscopy, Fluorescence; Muscle, Smooth, Vascular; Nitrates; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Pulmonary Artery; Receptor, Endothelin A; Secondary Prevention; Sheep; Superoxides; Tyrosine | 2001 |
Oxidative stress and reactive nitrogen species generation during renal ischemia.
Topics: Aldehydes; Animals; Blood Urea Nitrogen; Creatinine; Free Radicals; Glutathione; Kidney; Male; Nitrates; Oxidation-Reduction; Oxidative Stress; Proteins; Random Allocation; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Time Factors; Tyrosine | 2001 |
Peroxynitrite formation from human myocardium after ischemia-reperfusion during open heart operation.
Topics: Adult; Aged; Cardiopulmonary Bypass; Creatine Kinase; Creatine Kinase, MB Form; Female; Heart Valve Prosthesis Implantation; Humans; Isoenzymes; Male; Malondialdehyde; Middle Aged; Myocardial Reperfusion Injury; Myocardium; Nitrates; Tyrosine | 2001 |
Sulfur-to-nitrogen transnitrosation: transfer of nitric oxide from S-nitroso compounds to diethanolamine and the role of intermediate sulfur-to-sulfur transnitrosation.
Topics: Chromatography, High Pressure Liquid; Cysteine; Ethanolamines; Homocysteine; Nitrates; Nitric Oxide; Nitrogen; Nitrosation; Nitroso Compounds; S-Nitrosothiols; Signal Transduction; Sulfhydryl Compounds; Sulfur; Time Factors | 2001 |
Acute hyperglycemia induces an oxidative stress in healthy subjects.
Topics: Adult; Biomarkers; Confounding Factors, Epidemiologic; Diabetic Angiopathies; Female; Glucose Clamp Technique; Hemodynamics; Humans; Hydrogen-Ion Concentration; Hyperglycemia; Male; Nitrates; Oxidative Stress; Tyrosine; Vasoconstriction | 2001 |
Peroxynitrite-induced tyrosine nitration and inhibition of protein kinase C.
Topics: Animals; Brain; Cysteine; Isoenzymes; Male; Neurodegenerative Diseases; Nitrates; Nitric Oxide Donors; Nitroprusside; Nitroso Compounds; Oxidants; Oxidation-Reduction; Penicillamine; Protein Kinase C; Protein Kinase C beta; Protein Kinase C-alpha; Rats; Rats, Sprague-Dawley; S-Nitrosothiols; Tissue Extracts; Tyrosine | 2001 |
Human Ogg1, a protein involved in the repair of 8-oxoguanine, is inhibited by nitric oxide.
Topics: Cholangiocarcinoma; DNA Damage; DNA Repair; DNA-Formamidopyrimidine Glycosylase; DNA, Complementary; Gene Expression; Guanine; Humans; N-Glycosyl Hydrolases; Nitrates; Nitric Oxide; Nitrosation; Oxidants; Oxidation-Reduction; Precipitin Tests; Transfection; Tumor Cells, Cultured; Zinc | 2001 |
PECAM-1/IgG attenuates peroxynitrite-mediated extremity reperfusion injury.
Topics: Animals; Hindlimb; Immunoglobulin G; Male; Nitrates; Oxidants; Platelet Endothelial Cell Adhesion Molecule-1; Rabbits; Recombinant Fusion Proteins; Reperfusion Injury | 2001 |
Involvement of nitric oxide in killing of Schistosoma mansoni sporocysts by hemocytes from resistant Biomphalaria glabrata.
Topics: Animals; Biomphalaria; Deferoxamine; Drug Antagonism; Hemocytes; Immunity, Innate; Nitrates; Nitric Oxide; Schistosoma mansoni; Schistosomiasis mansoni; Uric Acid | 2001 |
Expressions of nitrotyrosine and TUNEL immunoreactivities in cultured rat spinal cord neurons after exposure to glutamate, nitric oxide, or peroxynitrite.
Topics: Animals; Antioxidants; Apoptosis; Cells, Cultured; Central Nervous System Diseases; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Free Radicals; Glutamic Acid; Immunohistochemistry; In Situ Nick-End Labeling; Interneurons; Motor Neurons; Nerve Degeneration; Neurons; Neurotoxins; Nitrates; Nitric Oxide Donors; Organ Culture Techniques; Oxidative Stress; Rats; Rats, Sprague-Dawley; Spinal Cord; Tyrosine | 2001 |
tert-Butylhydroperoxide induces peroxynitrite-dependent mitochondrial permeability transition leading PC12 cells to necrosis.
Topics: Adenosine Triphosphate; Animals; Cell Death; Cell Membrane; Cell Membrane Permeability; Dose-Response Relationship, Drug; Energy Metabolism; Enzyme Inhibitors; Lipid Peroxidation; Lipid Peroxides; Membrane Lipids; Mitochondria; Necrosis; Nerve Degeneration; Neurotoxins; Nitrates; Oxidative Stress; PC12 Cells; Rats; tert-Butylhydroperoxide | 2001 |
Aging increases the susceptiblity to methamphetamine-induced dopaminergic neurotoxicity in rats: correlation with peroxynitrite production and hyperthermia.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Brain Chemistry; Central Nervous System Stimulants; Corpus Striatum; Dopamine; Dose-Response Relationship, Drug; Fever; Homovanillic Acid; Male; Methamphetamine; Nitrates; Oxidative Stress; Rats; Rats, Sprague-Dawley; Tyrosine | 2001 |
Effects of oxidant stress on inflammation and survival of iNOS knockout mice after marrow transplantation.
Topics: Animals; Bone Marrow Transplantation; Bronchoalveolar Lavage Fluid; Cyclophosphamide; Female; Immunosuppressive Agents; Interferon-gamma; Macrophages; Mice; Mice, Congenic; Mice, Inbred C57BL; Mice, Knockout; Monocytes; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; Oxidative Stress; Pneumonia; Survival Rate; T-Lymphocytes; Tumor Necrosis Factor-alpha; Tyrosine | 2001 |
Peroxynitrite-induced nitrotyrosination of proteins is blocked by direct 5-lipoxygenase inhibitor zileuton.
Topics: Animals; Blotting, Western; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Female; Hydroxyurea; Leukotriene B4; Lipoxygenase Inhibitors; Nitrates; omega-N-Methylarginine; Precipitin Tests; Proteins; Rats; Rats, Wistar; Tyrosine | 2001 |
Inhibition of acetylcholine synthesis and tyrosine nitration induced by peroxynitrite are differentially prevented by antioxidants.
Topics: Acetates; Acetylcholine; Animals; Antioxidants; Biological Transport; Carbon Radioisotopes; Choline; Choline O-Acetyltransferase; Drug Interactions; Molsidomine; Nitrates; Oxidants; Reducing Agents; Torpedo; Tyrosine; Uric Acid | 2001 |
Induction of alpha-synuclein aggregation by intracellular nitrative insult.
Topics: alpha-Synuclein; Ammonium Chloride; beta-Synuclein; Cell Line; Cysteine Endopeptidases; Enzyme Inhibitors; Humans; Inclusion Bodies; Intracellular Fluid; Kidney; Lysosomes; Macromolecular Substances; Multienzyme Complexes; Nerve Tissue Proteins; Neurodegenerative Diseases; Nitrates; Nitric Oxide; Oxidants; Proteasome Endopeptidase Complex; Protein Binding; Superoxides; Synucleins; Transfection; Ubiquitins | 2001 |
An alternative signaling pathway based on nitryl chloride during intercellular induction of apoptosis.
Topics: Animals; Apoptosis; Cell Line, Transformed; Cells, Cultured; Coculture Techniques; Fibroblasts; HL-60 Cells; Humans; Hydroxyl Radical; Hypochlorous Acid; Macrophages; Mice; Nitrates; Nitric Oxide; Nitrites; Rats; Signal Transduction; Superoxide Dismutase; Superoxides; Transforming Growth Factor beta | 2001 |
Mechanisms of nitrogen oxide-mediated disruption of metalloprotein function: an examination of the copper-responsive yeast transcription factor Ace1.
Topics: Copper; DNA-Binding Proteins; Dose-Response Relationship, Drug; Metalloproteins; Nitrates; Nitrogen Oxides; Oxygen; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Transcription Factors | 2001 |
Partial protection by poly(ADP-ribose) polymerase inhibitors from nitroxyl-induced cytotoxity in thymocytes.
Topics: Animals; Apoptosis; Benzamides; Caspases; Cells, Cultured; DNA Damage; DNA Fragmentation; Enzyme Activation; Enzyme Inhibitors; Male; Mice; Mice, Inbred C57BL; Mitochondria; Nitrates; Nitrites; Nitrogen Oxides; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Protective Agents; Thymus Gland; Tyrosine | 2001 |
Peroxynitrite reacts with 8-nitropurines to yield 8-oxopurines.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Chromatography, High Pressure Liquid; Deoxyguanosine; DNA Adducts; Guanine; Nitrates; Xanthine; Xanthines | 2002 |
Peroxynitrite-mediated stress is associated with proliferation of human metastatic colorectal carcinoma in the liver.
Topics: Adenocarcinoma; Aged; Apoptosis; Cell Division; Colorectal Neoplasms; Female; Humans; Immunoenzyme Techniques; Liver Neoplasms; Male; Middle Aged; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Oxidants; Oxidative Stress; Proliferating Cell Nuclear Antigen; Reactive Oxygen Species; Tyrosine | 2002 |
The Mechanism by which 4-hydroxy-2,2,6,6-tetramethylpiperidene-1-oxyl (tempol) diverts peroxynitrite decomposition from nitrating to nitrosating species.
Topics: Antioxidants; Carbon Dioxide; Cyclic N-Oxides; Electron Spin Resonance Spectroscopy; Nitrates; Nitro Compounds; Nitroso Compounds; Oxidation-Reduction; Spin Labels | 2002 |
Transformed cell-derived reactive oxygen species support and inhibit nitric oxide-mediated apoptosis induction.
Topics: Apoptosis; Cell Line, Transformed; Cells, Cultured; Humans; Hydrogen Peroxide; Nitrates; Nitric Oxide; Reactive Oxygen Species; Signal Transduction; Superoxide Dismutase; Superoxides | 2002 |
Superoxide and nitric oxide: consequences of varying rates of production and consumption: a theoretical treatment.
Topics: Animals; Cell Death; Electron Spin Resonance Spectroscopy; Free Radicals; Hydrogen Peroxide; Models, Theoretical; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Superoxide Dismutase; Superoxides | 2002 |
Peroxynitrite and the regulation of Na(+),K(+)-ATPase activity by angiotensin II in the rat proximal tubule.
Topics: Angiotensin II; Animals; Deferoxamine; Dose-Response Relationship, Drug; Kidney Tubules, Proximal; Male; Nitrates; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley; Reactive Nitrogen Species; Sodium-Potassium-Exchanging ATPase; Superoxide Dismutase; Uric Acid | 2002 |
Patterns of oxidized epitopes, but not NF-kappa B expression, change during atherogenesis in WHHL rabbits.
Topics: Aldehydes; Animals; Arteriosclerosis; Epitopes; Hypochlorous Acid; Immunohistochemistry; Malondialdehyde; Nitrates; Oxidation-Reduction; Rabbits | 2003 |
Total oxyradical scavenging capacity toward different reactive oxygen species in seminal plasma and sperm cells.
Topics: Adult; Free Radical Scavengers; Free Radicals; Humans; Hydroxyl Radical; Leukocytes; Male; Nitrates; Oxidants; Peroxides; Reactive Oxygen Species; Semen; Sperm Motility; Spermatozoa | 2003 |
Peroxynitrate and peroxynitrite: a complete basis set investigation of similarities and differences between these NOx species.
Topics: Models, Molecular; Nitrates; Nitrites; Oxidation-Reduction; Peroxynitrous Acid | 2003 |
Human plasminogen is highly susceptible to peroxynitrite inactivation.
Topics: Antithrombin III; Chromogenic Compounds; Data Interpretation, Statistical; Diabetes Mellitus; Drug Combinations; Enzyme Inhibitors; Fructose; Glucose; Humans; Molsidomine; Nitrates; Oxidants; Plasma; Plasminogen; Streptokinase | 2003 |
Detection of superoxide and peroxynitrite in model systems and mitochondria by the luminol analogue L-012.
Topics: Animals; Cell-Free System; Fluorescent Dyes; Luminescent Measurements; Luminol; Mitochondria; Nitrates; Nitrogen Oxides; Oxidation-Reduction; Rats; Reactive Oxygen Species; Superoxides | 2004 |
The outer-sphere oxidation of nitrosyliron(II)hemoglobin by peroxynitrite leads to the release of nitrogen monoxide.
Topics: Carbon Dioxide; Catalysis; Hemoglobins; Humans; Hydrogen-Ion Concentration; Iron; Kinetics; Nitrates; Nitrogen; Nitrogen Oxides; Oxidation-Reduction | 2004 |
Evaluation of nitrotyrosine-containing proteins in blood platelets.
Topics: Animals; Blood Platelets; Blotting, Western; Cattle; Electrophoresis, Polyacrylamide Gel; Enzyme-Linked Immunosorbent Assay; Humans; Nitrates; Serum Albumin, Bovine; Tyrosine | 2004 |
High level ab initio study of the structure and vibrational spectra of HO(2)NO(2).
Topics: Algorithms; Computer Simulation; Models, Chemical; Models, Molecular; Molecular Conformation; Nitrates; Vibration | 2004 |
Characterization of the influence of nitric oxide donors on intestinal absorption of macromolecules.
Topics: 1,2-Dihydroxybenzene-3,5-Disulfonic Acid Disodium Salt; Adenosine Triphosphate; Animals; Benzoates; Colon; Dextrans; Drug Synergism; Fluorescein-5-isothiocyanate; Free Radical Scavengers; Hydrazines; Hydroxyl Radical; Imidazoles; Intestinal Absorption; Macromolecular Substances; Male; Nitrates; Nitric Oxide; Nitric Oxide Donors; Nitroso Compounds; Rats; Rats, Wistar; Superoxides; Triazenes | 2004 |
Mass spectrometric identification of 4-hydroxy-2,5-dioxo-imidazolidine-4-carboxylic acid during oxidation of 8-oxoguanosine by peroxynitrite and KHSO5/CoCl2.
Topics: Carboxylic Acids; Guanosine; Imidazolidines; Nitrates; Oxidants; Spectrometry, Mass, Electrospray Ionization | 2004 |
Spiroiminodihydantoin and guanidinohydantoin are the dominant products of 8-oxoguanosine oxidation at low fluxes of peroxynitrite: mechanistic studies with 18O.
Topics: Chromatography, High Pressure Liquid; Guanidines; Guanosine; Models, Chemical; Nitrates; Oxidation-Reduction; Oxygen Isotopes; Spiro Compounds | 2004 |
Kinetics and mechanism of *NO2 reacting with various oxidation states of myoglobin.
Topics: Animals; Free Radicals; Horses; Kinetics; Metmyoglobin; Myoglobin; Nitrates; Nitrogen Dioxide; Oxidation-Reduction; Pulse Radiolysis; Spectrophotometry | 2004 |
Flavonoids and tyrosine nitration: structure-activity relationship correlation with enthalpy of formation.
Topics: Flavonoids; Models, Chemical; Models, Molecular; Nitrates; Nitrogen; Structure-Activity Relationship; Thermodynamics; Tyrosine | 2005 |
The use of pholasin as a probe for the determination of plasma total antioxidant capacity.
Topics: Adult; Antioxidants; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Firefly Luciferin; Humans; Middle Aged; Molecular Probes; Nitrates; Reactive Oxygen Species; Time Factors | 2006 |
15N CIDNP investigations of the peroxynitric acid nitration of L-tyrosine and of related compounds.
Topics: Ascorbic Acid; Cysteine; Glutathione; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Nitrates; Nitrogen; Nitrogen Isotopes; Phenols; Solvents; Temperature; Tyrosine | 2006 |
Nitration of human plasminogen by RAW 264.7 macrophages reduces streptokinase-induced plasmin activity.
Topics: Animals; Cells, Cultured; Dose-Response Relationship, Drug; Down-Regulation; Enzyme Activation; Fibrinolysin; Humans; Macrophages; Mice; Nitrates; Oxidants; Phagocytosis; Plasminogen; Streptokinase; Time Factors | 2006 |
Effects of MnSOD-plasmid liposome gene therapy on antioxidant levels in irradiated murine oral cavity orthotopic tumors.
Topics: Animals; Antioxidants; Cell Line, Tumor; Cell Survival; Disease Models, Animal; Genetic Therapy; Hydrogen Peroxide; Liposomes; Mice; Mouth; Mouth Neoplasms; Nitrates; Plasmids; Superoxide Dismutase; Time Factors | 2007 |
Nitric oxide synthase partial uncoupling as a key switching mechanism for the NO/ONOO- cycle.
Topics: Drug Hypersensitivity; Fatigue Syndrome, Chronic; Fibromyalgia; Humans; Models, Biological; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Stress Disorders, Post-Traumatic; Uncoupling Agents | 2007 |
Reaction of retinol with peroxynitrite.
Topics: Chromatography, High Pressure Liquid; Molecular Structure; Nitrates; Nitrogen; Oxidation-Reduction; Stereoisomerism; Vitamin A | 2007 |
Dose dependent effects of reactive oxygen and nitrogen species on the function of neuronal nitric oxide synthase.
Topics: Biopterins; Dose-Response Relationship, Drug; Electron Spin Resonance Spectroscopy; Enzyme Inhibitors; Hydrogen Peroxide; Hydroxyl Radical; Kinetics; Nitrates; Nitric Oxide Synthase Type I; Oxidants; Oxidation-Reduction; Oxidative Stress; Oxygen; Reactive Nitrogen Species; Reactive Oxygen Species; Superoxides | 2008 |
A novel immunosuppressive pathway involving peroxynitrite-mediated [corrected] nitration of platelet antigens within antigen-presenting cells.
Topics: Animals; Antibodies, Anti-Idiotypic; Antigen-Presenting Cells; Antigens, Human Platelet; Guanidines; Male; Membrane Glycoproteins; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Knockout; NADPH Oxidase 2; NADPH Oxidases; Nitrates; Nitric Oxide Synthase Type II; Platelet Transfusion; Signal Transduction | 2008 |
Direct evidence of singlet molecular oxygen generation from peroxynitrate, a decomposition product of peroxynitrite.
Topics: Hydrogen-Ion Concentration; Nitrates; Peroxynitrous Acid; Singlet Oxygen | 2009 |
Peroxynitrate is formed rapidly during decomposition of peroxynitrite at neutral pH.
Topics: Hydrogen-Ion Concentration; Nitrates; Peroxynitrous Acid | 2009 |
Thermochemistry and UV spectroscopy of alkyl peroxynitrates.
Topics: Computer Simulation; Molecular Conformation; Nitrates; Quantum Theory; Spectrophotometry, Ultraviolet; Stereoisomerism; Thermodynamics | 2010 |
Involvement of autoimmunity in the pathogenesis of aggressive periodontitis.
Topics: Adult; Aggressive Periodontitis; Autoantibodies; Autoantigens; Autoimmunity; Chronic Periodontitis; Citrulline; Collagen Type I; Collagen Type III; Electrophoresis, Polyacrylamide Gel; Extracellular Matrix; Female; Filaggrin Proteins; Fluorescence; Gingivitis; Humans; Hydroxyl Radical; Hypochlorous Acid; Imaging, Three-Dimensional; Intermediate Filament Proteins; Male; Middle Aged; Nitrates; Oxidants; Phosphoproteins; Protein Precursors; Protein Processing, Post-Translational; Reactive Oxygen Species; Young Adult | 2010 |
Ion-exchange chromatographic analysis of peroxynitric acid.
Topics: Chromatography, Ion Exchange; Nitrates; Solutions | 2016 |
Ohr plays a central role in bacterial responses against fatty acid hydroperoxides and peroxynitrite.
Topics: Bacterial Proteins; Escherichia coli; Fatty Acids; Host-Pathogen Interactions; Hydrogen Peroxide; Molecular Docking Simulation; Nitrates; Pseudomonas aeruginosa | 2017 |
Sodium nitrite potentiates antimicrobial photodynamic inactivation: possible involvement of peroxynitrate.
Topics: Anti-Bacterial Agents; Drug Synergism; Escherichia coli; Fullerenes; Light; Methicillin-Resistant Staphylococcus aureus; Microbial Viability; Models, Molecular; Molecular Conformation; Nitrates; Sodium Nitrite | 2019 |
High microbicidal effect of peroxynitric acid on biofilm-infected dentin in a root carious tooth model and verification of tissue safety.
Topics: Aged; Biofilms; Dental Caries; Dentin; Humans; Nitrates; Streptococcus mutans | 2020 |
Kinetics Analysis of the Reactions between Peroxynitric Acid and Amino Acids.
Topics: Amino Acids; Bacillus subtilis; Kinetics; Methionine; Nitrates; Reactive Nitrogen Species; Reactive Oxygen Species | 2020 |
Kinetics of Bacterial Inactivation by Peroxynitric Acid in the Presence of Organic Contaminants.
Topics: Amino Acids; Anti-Bacterial Agents; Bacillus subtilis; Disinfectants; Disinfection; Enterococcus faecium; Escherichia coli; Hypochlorous Acid; Kinetics; Nitrates; Serum Albumin, Bovine | 2021 |
ROS/RNS and Base Dual Activatable Merocyanine-Based NIR-II Fluorescent Molecular Probe for in vivo Biosensing.
Topics: Animals; Benzopyrans; Biosensing Techniques; Colitis; Cystitis; Fluorescent Dyes; Hydrogen Peroxide; Indoles; Infrared Rays; Mice; Molecular Structure; Nitrates; Reactive Nitrogen Species; Reactive Oxygen Species | 2021 |
Peroxynitric acid inhibits amyloid β aggregation.
Topics: Alzheimer Disease; Amyloid; Amyloid beta-Peptides; Amyloidogenic Proteins; Humans; Nitrates; Peptide Fragments | 2023 |