Page last updated: 2024-08-24

peroxynitric acid and ascorbic acid

peroxynitric acid has been researched along with ascorbic acid in 35 studies

Research

Studies (35)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's24 (68.57)18.2507
2000's11 (31.43)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Jin, X; Pryor, WA; Squadrito, GL1
Ahmed, N; Daniel, LN; Gannett, P; Liu, K; Mao, Y; Rojanasakul, Y; Saffiotti, U; Shi, X1
Bartlett, D; Bounds, PL; Church, DF; Koppenol, WH1
Cross, CE; Darley-Usmar, V; Halliwell, B; Kaur, H; O'Neill, CA; Smith, D; Van der Vliet, A1
Lenhart, A; Mao, Y; Shi, X1
Augusto, O; Junqueira, VB; Santos, AM; Vásquez-Vivar, J1
Vatassery, GT1
Halliwell, B; Whiteman, M1
Akaike, A; Kawamura, T; Kimura, J; Kitamura, Y; Sawada, H; Shimohama, S; Taniguchi, T1
Dallner, G; Ernster, L; Forsmark-Andrée, P; Persson, B; Radi, R1
Clark, DA; Liu, X; Mannick, EE; Miller, MJ; Sandoval, M; Zhang, XJ1
Minetti, M; Pietraforte, D2
Bassenge, E; Dikalov, S; Skatchkov, M1
Asano, Y; Hiramoto, K; Kikugawa, K; Tomiyama, S1
Bloom, FE; Gruol, DL; Horn, TF; Sorg, O; Yu, N1
Quach, HT; Smith, WE; Ungar, F; Vatassery, GT1
Minetti, M; Scorza, G1
Chen, C; Mori, A; Wei, T; Xin, W; Zhao, B1
Böhm, F; Edge, R; McGarvey, DJ; Truscott, TG1
Bast, A; Cross, CE; Hoen, PA; van der Vliet, A; Wong, PS1
Regoli, F; Winston, GW1
Batinić-Haberle, I; Ferrer-Sueta, G; Fridovich, I; Radi, R; Spasojević, I1
Crow, JP1
de Groot, H; Kirsch, M1
Carbone, V; Marino, G; Minetti, M; Pietraforte, D; Salzano, AM; Scorza, G1
May, SW; Neumann, HM; Overcast, JD; Robertson, K; Woznichak, MM1
Alvarez, S; Arnaiz, SL; Boveris, A; Carreras, MC; Poderoso, JJ; Schöpfer, F; Valdez, LB1
Doi, U; Kato, Y; Niwa, T; Osawa, T1
Deby, CM; Deby-Dupont, GP; Henrotin, YE; Lamy, MM; Mouithys-Mickalad, AM; Reginster, JY; Zheng, SX1
Barbouti, A; Doulias, PT; Galaris, D; Ischiropoulos, H1
de Ruijter-Heijstek, FC; Huisman, A; Rabelink, TJ; Stroes, ES; van Faassen, EE; Vanin, AF1
Cantoni, O; Cellini, B; Dachà, M; De Sanctis, R; Fiorani, M; Guidarelli, A1
Baliga, RS; Bauer, JA; Carnes, CA; Chung, MK; Hamlin, RL; Kanderian, A; McCarthy, PM; Nakayama, H; Nakayama, T; Pavia, S; Piao, S; Van Wagoner, DR1
Kirsch, M; Lehnig, M1

Trials

1 trial(s) available for peroxynitric acid and ascorbic acid

ArticleYear
Ascorbate attenuates atrial pacing-induced peroxynitrite formation and electrical remodeling and decreases the incidence of postoperative atrial fibrillation.
    Circulation research, 2001, Sep-14, Volume: 89, Issue:6

    Topics: Aged; Animals; Antioxidants; Ascorbic Acid; Atrial Fibrillation; Cardiac Pacing, Artificial; Coronary Artery Bypass; Dogs; Electrophysiology; Female; Heart Atria; Humans; Male; Middle Aged; Multivariate Analysis; Nitrates; Time Factors; Treatment Outcome; Tyrosine

2001

Other Studies

34 other study(ies) available for peroxynitric acid and ascorbic acid

ArticleYear
Stopped-flow kinetic study of the reaction of ascorbic acid with peroxynitrite.
    Archives of biochemistry and biophysics, 1995, Sep-10, Volume: 322, Issue:1

    Topics: Ascorbic Acid; Electron Transport; Free Radicals; Hydrogen-Ion Concentration; In Vitro Techniques; Kinetics; Methionine; Models, Chemical; Nitrates; Oxidation-Reduction

1995
Generation of thiyl and ascorbyl radicals in the reaction of peroxynitrite with thiols and ascorbate at physiological pH.
    Journal of inorganic biochemistry, 1994, Nov-01, Volume: 56, Issue:2

    Topics: Ascorbic Acid; Cyclic N-Oxides; Dehydroascorbic Acid; Electron Spin Resonance Spectroscopy; Free Radicals; Hydrogen-Ion Concentration; Models, Biological; Nitrates; Spin Labels; Sulfhydryl Compounds

1994
The kinetics of the oxidation of L-ascorbic acid by peroxynitrite.
    Free radical biology & medicine, 1995, Volume: 18, Issue:1

    Topics: Ascorbic Acid; Electron Spin Resonance Spectroscopy; Hydrogen-Ion Concentration; Kinetics; Mathematics; Nitrates; Oxidation-Reduction; Spectrophotometry; Temperature; Thermodynamics

1995
Interactions of peroxynitrite with human plasma and its constituents: oxidative damage and antioxidant depletion.
    The Biochemical journal, 1994, Oct-01, Volume: 303 ( Pt 1)

    Topics: Antioxidants; Ascorbic Acid; Blood Proteins; Glutathione; Humans; Kinetics; Lipid Peroxides; Nitrates; Oxidants; Oxidation-Reduction; Serum Albumin; Vitamin E

1994
ESR spin trapping investigation on peroxynitrite decomposition: no evidence for hydroxyl radical production.
    Biochemical and biophysical research communications, 1994, Sep-30, Volume: 203, Issue:3

    Topics: Ascorbic Acid; Cyclic N-Oxides; Cysteine; Electron Spin Resonance Spectroscopy; Formates; Free Radicals; Glutathione; Hydroxyl Radical; Nitrates; Penicillamine; Spin Labels

1994
Peroxynitrite-mediated formation of free radicals in human plasma: EPR detection of ascorbyl, albumin-thiyl and uric acid-derived free radicals.
    The Biochemical journal, 1996, Mar-15, Volume: 314 ( Pt 3)

    Topics: Ascorbic Acid; Cyclic N-Oxides; Electron Spin Resonance Spectroscopy; Free Radicals; Humans; Kinetics; Nitrates; Oxygen Consumption; Serum Albumin; Spin Labels; Time Factors; Uric Acid

1996
Oxidation of vitamin E, vitamin C, and thiols in rat brain synaptosomes by peroxynitrite.
    Biochemical pharmacology, 1996, Aug-23, Volume: 52, Issue:4

    Topics: Animals; Ascorbic Acid; Brain; Dose-Response Relationship, Drug; Humans; Hydrogen-Ion Concentration; Nitrates; Rats; Sulfhydryl Compounds; Synaptosomes; Vitamin E

1996
Protection against peroxynitrite-dependent tyrosine nitration and alpha 1-antiproteinase inactivation by ascorbic acid. A comparison with other biological antioxidants.
    Free radical research, 1996, Volume: 25, Issue:3

    Topics: alpha 1-Antitrypsin; Antioxidants; Arthritis, Rheumatoid; Ascorbic Acid; Humans; Lipid Peroxidation; Nitrates; Oxidation-Reduction; Oxidative Stress; Pancreatic Elastase; Synovial Fluid; Tyrosine

1996
Mechanism of resistance to NO-induced neurotoxicity in cultured rat dopaminergic neurons.
    Journal of neuroscience research, 1996, Nov-15, Volume: 46, Issue:4

    Topics: 1-Methyl-4-phenylpyridinium; Animals; Antioxidants; Ascorbic Acid; Cell Survival; Cells, Cultured; Dopamine; Drug Resistance; Mesencephalon; Nerve Tissue Proteins; Neurons; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Oxidation-Reduction; Parkinson Disease; Rats; Tyrosine 3-Monooxygenase

1996
Oxidative modification of nicotinamide nucleotide transhydrogenase in submitochondrial particles: effect of endogenous ubiquinol.
    Archives of biochemistry and biophysics, 1996, Dec-01, Volume: 336, Issue:1

    Topics: Adenosine Diphosphate; Animals; Ascorbic Acid; Blotting, Western; Cattle; Ferric Compounds; Kinetics; Lipid Peroxides; NAD; NADP; NADP Transhydrogenases; Nitrates; Oxidation-Reduction; Peptide Mapping; Stress, Physiological; Submitochondrial Particles; Tyrosine; Ubiquinone

1996
Peroxynitrite-induced apoptosis in T84 and RAW 264.7 cells: attenuation by L-ascorbic acid.
    Free radical biology & medicine, 1997, Volume: 22, Issue:3

    Topics: Animals; Apoptosis; Ascorbic Acid; Cell Line; Cell Survival; Culture Media; Epithelium; Free Radical Scavengers; Humans; Intestines; Macrophages; Mice; Necrosis; Nitrates; Trypan Blue

1997
One-electron oxidation pathway of peroxynitrite decomposition in human blood plasma: evidence for the formation of protein tryptophan-centred radicals.
    The Biochemical journal, 1997, Feb-01, Volume: 321 ( Pt 3)

    Topics: Ascorbic Acid; Benzenesulfonates; Bicarbonates; Blood Proteins; Chromatography, Gel; Electron Spin Resonance Spectroscopy; Electron Transport; Free Radicals; Glutathione; Humans; Methionine; Nitrates; Nitroso Compounds; Peptides; Pronase; Spin Trapping; Sulfhydryl Compounds; Tryptophan; Uric Acid

1997
Spin trapping of superoxide radicals and peroxynitrite by 1-hydroxy-3-carboxy-pyrrolidine and 1-hydroxy-2,2,6, 6-tetramethyl-4-oxo-piperidine and the stability of corresponding nitroxyl radicals towards biological reductants.
    Biochemical and biophysical research communications, 1997, Feb-24, Volume: 231, Issue:3

    Topics: Animals; Ascorbic Acid; Cysteine; Electron Spin Resonance Spectroscopy; Glutathione; Muscle, Smooth; Nitrates; Oxidation-Reduction; Piperidines; Pyrrolidines; Spin Trapping; Superoxides

1997
beta-Carotene effectively scavenges toxic nitrogen oxides: nitrogen dioxide and peroxynitrous acid.
    FEBS letters, 1997, Mar-10, Volume: 404, Issue:2-3

    Topics: Amiloride; Ascorbic Acid; beta Carotene; Docosahexaenoic Acids; Electron Spin Resonance Spectroscopy; Free Radical Scavengers; Nitrates; Nitrogen Dioxide; Vitamin E

1997
Inhibition of astrocyte glutamate uptake by reactive oxygen species: role of antioxidant enzymes.
    Molecular medicine (Cambridge, Mass.), 1997, Volume: 3, Issue:7

    Topics: Animals; Animals, Newborn; Antioxidants; Ascorbic Acid; Astrocytes; Catalase; Free Radical Scavengers; Glutamic Acid; Glutathione Peroxidase; Hydrogen Peroxide; Mice; Mice, Inbred C57BL; Nitrates; Nitric Oxide; Reactive Oxygen Species; Superoxides; Thiourea

1997
Oxidation of cholesterol in synaptosomes and mitochondria isolated from rat brains.
    Lipids, 1997, Volume: 32, Issue:8

    Topics: Animals; Antioxidants; Ascorbic Acid; Borohydrides; Brain; Chelating Agents; Cholesterol; Chromatography, Gas; Ferrous Compounds; Male; Mitochondria; Nitrates; Oxidation-Reduction; Oxidative Stress; Rats; Rats, Inbred F344; Synaptosomes; Vitamin E

1997
Direct ESR detection or peroxynitrite-induced tyrosine-centred protein radicals in human blood plasma.
    The Biochemical journal, 1997, Aug-01, Volume: 325 ( Pt 3)

    Topics: Amino Acid Sequence; Ascorbic Acid; Electron Spin Resonance Spectroscopy; Free Radicals; Humans; Molecular Sequence Data; Nitrates; Sulfhydryl Compounds; Tyrosine; Uric Acid

1997
One-electron oxidation pathway of thiols by peroxynitrite in biological fluids: bicarbonate and ascorbate promote the formation of albumin disulphide dimers in human blood plasma.
    The Biochemical journal, 1998, Jan-15, Volume: 329 ( Pt 2)

    Topics: Ascorbic Acid; Blood Proteins; Chromatography, Gel; Chromatography, High Pressure Liquid; Dimerization; Electron Spin Resonance Spectroscopy; Electrons; Free Radicals; Humans; Nitrates; Oxidation-Reduction; Serum Albumin; Sodium Bicarbonate; Sulfhydryl Compounds

1998
EPC-K1 attenuates peroxynitrite-induced apoptosis in cerebellar granule cells.
    Biochemistry and molecular biology international, 1998, Volume: 46, Issue:1

    Topics: Adenosine Triphosphate; Animals; Antioxidants; Apoptosis; Ascorbic Acid; Cell Survival; Cells, Cultured; Cerebellum; DNA Fragmentation; Lipid Peroxidation; Membrane Fluidity; Neurons; Nitrates; Rats; Rats, Wistar; Thiobarbituric Acid Reactive Substances; Vitamin E

1998
Beta-carotene with vitamins E and C offers synergistic cell protection against NOx.
    FEBS letters, 1998, Oct-09, Volume: 436, Issue:3

    Topics: Antioxidants; Ascorbic Acid; beta Carotene; Cell Survival; Drug Synergism; Free Radicals; Humans; Jurkat Cells; Lymphocytes; Nitrates; Nitrogen Dioxide; Oxidants; Vitamin E

1998
Formation of S-nitrosothiols via direct nucleophilic nitrosation of thiols by peroxynitrite with elimination of hydrogen peroxide.
    The Journal of biological chemistry, 1998, Nov-13, Volume: 273, Issue:46

    Topics: Ascorbic Acid; Cells, Cultured; Chromatography, High Pressure Liquid; Electron Spin Resonance Spectroscopy; Glutathione; Humans; Hydrogen Peroxide; Hydrogen-Ion Concentration; Kinetics; Luminescent Measurements; Nitrates; Nitric Oxide

1998
Quantification of total oxidant scavenging capacity of antioxidants for peroxynitrite, peroxyl radicals, and hydroxyl radicals.
    Toxicology and applied pharmacology, 1999, Apr-15, Volume: 156, Issue:2

    Topics: Amidines; Antioxidants; Ascorbic Acid; Chromatography, Gas; Free Radical Scavengers; Free Radicals; Hydroxyl Radical; Methionine; Molsidomine; Nitrates; Nitric Oxide Donors; Oxidants; Oxidation-Reduction; Peroxides

1999
Catalytic scavenging of peroxynitrite by isomeric Mn(III) N-methylpyridylporphyrins in the presence of reductants.
    Chemical research in toxicology, 1999, Volume: 12, Issue:5

    Topics: Ascorbic Acid; Catalysis; Free Radical Scavengers; Glutathione; Hydrogen-Ion Concentration; Isomerism; Kinetics; Metalloporphyrins; Nitrates; Oxidants; Oxidation-Reduction; Porphyrins; Reducing Agents; Tyrosine; Uric Acid

1999
Manganese and iron porphyrins catalyze peroxynitrite decomposition and simultaneously increase nitration and oxidant yield: implications for their use as peroxynitrite scavengers in vivo.
    Archives of biochemistry and biophysics, 1999, Nov-01, Volume: 371, Issue:1

    Topics: Ascorbic Acid; Catalysis; Free Radical Scavengers; Iron; Kinetics; Manganese; Metalloporphyrins; Models, Chemical; Molecular Conformation; Molecular Structure; Nitrates; Oxidants

1999
Ascorbate is a potent antioxidant against peroxynitrite-induced oxidation reactions. Evidence that ascorbate acts by re-reducing substrate radicals produced by peroxynitrite.
    The Journal of biological chemistry, 2000, Jun-02, Volume: 275, Issue:22

    Topics: Animals; Antioxidants; Ascorbic Acid; Cattle; Free Radicals; NAD; Nitrates; Oxidation-Reduction; Rhodamines

2000
Scavenging of peroxynitrite by oxyhemoglobin and identification of modified globin residues.
    Biochemistry, 2000, Jun-06, Volume: 39, Issue:22

    Topics: Ascorbic Acid; Carbon Dioxide; Dipeptides; Erythrocytes; Free Radical Scavengers; Globins; Humans; Immunoelectrophoresis; Mass Spectrometry; Nitrates; Oxyhemoglobins; Tyrosine

2000
Reaction of phenylaminoethyl selenides with peroxynitrite and hydrogen peroxide.
    Archives of biochemistry and biophysics, 2000, Jul-15, Volume: 379, Issue:2

    Topics: Antihypertensive Agents; Antioxidants; Ascorbic Acid; Chromatography, High Pressure Liquid; Ethylamines; Hydrogen Peroxide; Hydrogen-Ion Concentration; Kinetics; Molecular Structure; Nitrates; Organoselenium Compounds; Oxidants; Oxidation-Reduction; Oxides; Oxidoreductases; Phenethylamines; Reactive Oxygen Species; Sulfur Compounds; Thermodynamics

2000
Reactions of peroxynitrite in the mitochondrial matrix.
    Free radical biology & medicine, 2000, Volume: 29, Issue:3-4

    Topics: Animals; Ascorbic Acid; Blotting, Western; Carbon Dioxide; Glutathione; Inhibitory Concentration 50; Kinetics; Mice; Mitochondria, Liver; NAD; Nitrates; Oxidation-Reduction; Spectrometry, Fluorescence; Superoxides; Tyrosine; Ubiquinone

2000
Antioxidative properties of phenolic antioxidants isolated from corn steep liquor.
    Journal of agricultural and food chemistry, 2001, Volume: 49, Issue:1

    Topics: Acetates; Animals; Antioxidants; Ascorbic Acid; Chromatography, High Pressure Liquid; Coumaric Acids; Erythrocyte Membrane; Fermentation; Lipoproteins; Magnetic Resonance Spectroscopy; Nitrates; Phenols; Rabbits; Tyrosine; Vitamin E; Zea mays

2001
In vitro study of the antioxidant properties of non steroidal anti-inflammatory drugs by chemiluminescence and electron spin resonance (ESR).
    Free radical research, 2000, Volume: 33, Issue:5

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Ascorbic Acid; Chlorine; Diclofenac; Electron Spin Resonance Spectroscopy; Free Radicals; Humans; In Vitro Techniques; Indicators and Reagents; Indomethacin; Iron; Kinetics; Lipid Peroxidation; Luminescent Measurements; Neutrophil Activation; Neutrophils; Nitrates; Reactive Oxygen Species; Sodium Hypochlorite; Spectrophotometry, Ultraviolet; Sulfonamides; Tetradecanoylphorbol Acetate

2000
SIN-1-induced DNA damage in isolated human peripheral blood lymphocytes as assessed by single cell gel electrophoresis (comet assay).
    Free radical biology & medicine, 2001, Mar-15, Volume: 30, Issue:6

    Topics: Ascorbic Acid; Calcium; Catalase; Chelating Agents; Comet Assay; Data Interpretation, Statistical; DNA Damage; DNA, Single-Stranded; Dose-Response Relationship, Drug; Egtazic Acid; Flow Cytometry; Humans; Kinetics; Lymphocytes; Microscopy, Ultraviolet; Molsidomine; Nitrates; Nitric Oxide Donors; Superoxide Dismutase

2001
Antioxidant capacity of mononitrosyl-iron-dithiocarbamate complexes: implications for NO trapping.
    Free radical biology & medicine, 2001, Apr-15, Volume: 30, Issue:8

    Topics: Air; Antioxidants; Ascorbic Acid; Cell Line; Cerium; Dimerization; Electron Spin Resonance Spectroscopy; Endothelium, Vascular; Ferrous Compounds; Kinetics; Ligands; Nitrates; Nitric Oxide; Oxidants; Sorbitol; Spin Labels; Spin Trapping; Superoxide Dismutase; Superoxides; Thiocarbamates

2001
Intracellular ascorbic acid enhances the DNA single-strand breakage and toxicity induced by peroxynitrite in U937 cells.
    The Biochemical journal, 2001, Jun-01, Volume: 356, Issue:Pt 2

    Topics: Ascorbic Acid; Dehydroascorbic Acid; DNA Damage; Ferricyanides; Free Radical Scavengers; Humans; Iron Chelating Agents; Nitrates; Oxidation-Reduction; U937 Cells

2001
15N CIDNP investigations of the peroxynitric acid nitration of L-tyrosine and of related compounds.
    Organic & biomolecular chemistry, 2006, Feb-21, Volume: 4, Issue:4

    Topics: Ascorbic Acid; Cysteine; Glutathione; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Nitrates; Nitrogen; Nitrogen Isotopes; Phenols; Solvents; Temperature; Tyrosine

2006