perospirone has been researched along with thiazoles in 98 studies
| Studies (perospirone) | Trials (perospirone) | Recent Studies (post-2010) (perospirone) | Studies (thiazoles) | Trials (thiazoles) | Recent Studies (post-2010) (thiazoles) |
|---|---|---|---|---|---|
| 111 | 24 | 26 | 33,179 | 2,100 | 12,330 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 19 (19.39) | 18.2507 |
| 2000's | 53 (54.08) | 29.6817 |
| 2010's | 21 (21.43) | 24.3611 |
| 2020's | 5 (5.10) | 2.80 |
| Authors | Studies |
|---|---|
| Hirose, A; Kato, T; Katsube, J; Nakamura, M; Ohno, Y; Shimizu, H; Tanaka, H | 1 |
| Hirose, A; Kato, T; Nakamura, M; Ohno, Y; Shimizu, H; Tanaka, H | 1 |
| Ikeda, K; Ishibashi, T; Ishida, K; Kato, T; Nakamura, M; Ohno, Y | 1 |
| Ikeda, K; Ishibashi, T; Ishida, K; Nakamura, M; Ohno, Y; Okada, K | 1 |
| Hirose, A; Kato, T; Maruoka, Y; Nakamura, M; Ohno, Y; Tatsuno, T | 1 |
| Antoku, F; Ishizumi, K; Kojima, A; Saji, I; Yoshigi, M | 1 |
| Ishibashi, T; Ishida, K; Nakamura, M; Ohno, Y; Okada, K | 1 |
| Ikeda, K; Ishibashi, T; Ishida, K; Nakamura, M; Ohno, Y; Tojima, R; Yasui, J | 1 |
| Ishibashi, T; Ishida-Tokuda, K; Morita, T; Nakamura, M; Ohno, Y; Sakamoto, H; Tojima, R; Wakabayashi, J | 1 |
| Ishibashi, T; Ishida, K; Nakamura, M; Ohno, Y | 1 |
| Ishibashi, T; Ishida-Tokuda, K; Nakamura, M; Ohno, Y | 1 |
| Amano, T; Ishihara, K; Matsubayashi, H; Sasa, M; Yu, H | 1 |
| Horisawa, T; Ishibashi, T; Ishida-Tokuda, K; Kawabe, A; Matsumoto, K; Nakamura, M; Ohno, Y; Sakamoto, H; Tagashira, R; Yabuuti, K | 1 |
| Nakamura, M; Ohno, Y; Tanaka, H | 1 |
| Ishikane, T; Koyama, T; Kusumi, I; Takahashi, Y | 1 |
| Matsumoto, K; Nakamura, M; Ohno, Y; Sakamoto, H | 1 |
| Ishibashi, T; Nakamura, M; Noguchi, H; Ohno, Y; Tagashira, R | 1 |
| Kameda, K; Koyama, T; Kusumi, I; Suzuki, K; Takahashi, Y | 1 |
| Ohno, Y | 1 |
| McClellan, K; Onrust, SV | 1 |
| de Paulis, T | 1 |
| Iseki, E; Kase, A; Katsuse, O; Kosaka, K; Oyama, I; Shoji, M; Togo, T; Uchikado, H | 1 |
| Inoue, Y; Tateishi, T; Yasui-Furukori, N | 1 |
| Nishikawa, T; Takeuchi, T | 1 |
| Koyama, T; Nakagawa, S | 1 |
| Amano, T; Matsubayashi, H; Sakai, N; Sasa, M; Seki, T; Shiwa, T | 1 |
| Honma, H; Iwasaki, S; Kondo, C; Masui, T; Matsubara, S; Osawa, T | 1 |
| Kawai, M; Minabe, Y; Mori, N; Takei, N; Tani, K; Yokoshima, T | 1 |
| Nakamura, M; Nishida, M | 1 |
| Inoue, Y; Iwakawa, M; Kojima, H; Nakamura, J; Soya, A; Terao, T; Ueda, N; Yoshimura, R | 1 |
| Katoh, S; Nisijima, K; Shioda, K; Yoshino, T; Yui, K | 1 |
| Furukori, H; Inoue, Y; Kaneko, S; Nakagami, T; Saito, M; Tateishi, T; Yasui-Furukori, N | 1 |
| Ito, C; Ojima, T; Sakurai, E; Watanabe, T; Yanai, K | 1 |
| Mori, K; Morinobu, S; Nagao, M; Okamoto, Y; Yamashita, H; Yamawaki, S | 2 |
| Kanamaru, H; Kitamura, A; Komuro, S; Mizuno, Y; Natsui, K; Yabuki, M | 1 |
| Koyama, T; Kusumi, I; Masui, T; Takahashi, Y | 3 |
| Abekawa, T; Kitaichi, Y; Koyama, T; Matsuyama, T | 1 |
| Fukuda, K; Ishida, S; Kageyama, M; Miyauchi, T; Ohashi, Y | 1 |
| Kinoshita, T; Kitashiro, M; Nobuhara, K; Okugawa, G | 1 |
| Egashira, N; Fujiwara, M; Harada, S; Iwasaki, K; Matsushita, M; Mishima, K; Nishimura, R; Okuno, R | 1 |
| Araki, T; Iwanami, A; Kasai, K; Kato, N; Kuwabara, H; Suga, M; Sumiyoshi, T; Yamasue, H | 1 |
| Hirayasu, Y; Kato, D; Kawanishi, C; Kishida, I; Matsumura, T; Nakagawa, M; Tamura, K | 1 |
| Asada, T; Mizukami, K; Moro, K; Sato, S; Tanaka, Y | 2 |
| Fujita, K; Okazaki, Y; Tanii, H | 1 |
| Harada, KI; Saito, T; Yamamoto, K | 1 |
| Araki, T; Iwanami, A; Kasai, K; Kato, N; Rogers, MA | 1 |
| Asami, T; Hirayasu, Y; Kato, D; Kawanishi, C; Nakamura, S; Roppongi, T; Shiozaki, K; Togo, T; Yoshimi, A | 1 |
| Iwata, Y; Minabe, Y; Mori, N; Nakamura, K; Okada, H; Ouchi, Y; Sekine, Y; Sugihara, G; Suzuki, K; Takei, N; Tsuchiya, KJ; Yoshikawa, E | 1 |
| Li, HD; Liu, WY; Ma, N; Wang, F; Xiang, DX; Zhang, BK; Zhu, RH; Zhu, YG | 1 |
| Hirayasu, Y; Karashima, A; Otsuka, T; Shioya, H; Sugiyama, N; Togo, T; Uehara, K; Yoshimi, A | 1 |
| Atsuta, H; Furuta, K; Hirasawa, T; Masaki, H; Nishikawa, T; Takeuchi, T; Yukizane, T | 1 |
| Li, HD; Li, KY; Ren, HY; Wang, F; Zhang, BK; Zhou, YG | 1 |
| Asai, K; Shimada, Y; Tanaka, Y; Ueda, H; Yoshida, S | 1 |
| Hamanaka, S; Kamijo, Y | 1 |
| Ishii, E; Ishimatsu, S; Kizu, J; Otani, N; Tsuchiya, M | 1 |
| Dierks, T; Irisawa, S; Isotani, T; Kikuchi, M; Kinoshita, T; Koenig, T; Okugawa, G; Strik, W; Yagyu, T; Yamada, K; Yoshimura, M | 1 |
| Arai, H; Higuchi, Y; Kurachi, M; Matsui, M; Meltzer, HY; Sumiyoshi, T; Takamiya, C | 1 |
| Bian, Q; Hashioka, S; Horikawa, H; Kanba, S; Kato, T; Mizoguchi, Y; Monji, A | 1 |
| Koyama, T; Kusumi, I; Masui, T | 1 |
| Fujita, Y; Hagiwara, H; Hashimoto, K; Ishima, T; Iyo, M; Kunitachi, S; Shirayama, Y | 1 |
| Matsuo, N; Okuyama, S; Yomiya, K | 1 |
| Li, HD; Li, KY; Zhou, YG | 1 |
| Fan, HW; Hu, Q; Ji, HJ; Xiao, DW; Zhou, XH; Zhu, YB; Zou, JJ | 1 |
| Kaneko, S; Nakagami, T; Saito, M; Sato, Y; Yasui-Furukori, N | 1 |
| Arai, H; Higuchi, Y; Itoh, T; Kawasaki, Y; Kurachi, M; Matsui, M; Sumiyoshi, C; Sumiyoshi, T; Suzuki, M | 1 |
| Kato, M; Kinoshita, T; Kishimoto, T; Koh, J; Matsumoto, N; Morikawa, M; Okugawa, G; Shinosaki, K; Wakeno, M; Yoneda, H | 1 |
| Arakawa, R; Ito, H; Okubo, Y; Okumura, M; Suhara, T; Takahashi, H; Takano, A; Takano, H | 1 |
| Fukui, N; Inoue, Y; Ono, S; Sawamura, K; Someya, T; Sugai, T; Suzuki, Y; Tsuneyama, N; Watanabe, J | 1 |
| Fujii, A; Furukori, H; Inoue, Y; Kaneko, S; Sugawara, N; Tsuchimine, S; Yasui-Furukori, N | 1 |
| Hori, H; Nakamura, J; Okamoto, T; Umene-Nakano, W; Yoshimura, R | 1 |
| Gen, K; Inoue, Y; Suzuki, H | 1 |
| Caccia, S | 1 |
| Morita, M; Nakayama, K | 1 |
| Fukui, N; Ono, S; Saito, M; Someya, T; Sugai, T; Suzuki, Y; Tsuneyama, N; Watanabe, J | 1 |
| Fujiki, R; Matsuoka, T; Mori, K; Morita, K; Shoji, Y; Uchimura, N | 1 |
| Kato, M; Kinoshita, T; Nishida, K; Okugawa, G; Sakai, S; Suwa, A; Takekita, Y; Wakeno, M | 1 |
| Higuchi, Y; Ito, T; Sumiyoshi, T; Suzuki, M | 1 |
| Suzuki, M; Takahashi, S; Uchiyama, M | 1 |
| Iwata, N; Kishi, T | 1 |
| Kono, B; Kurosawa, H; Takei, D; Yomiya, K | 1 |
| Iwata, N; Kishi, T; Matsuda, Y | 1 |
| Fabbri, C; Kato, M; Kinoshita, T; Koshikawa, Y; Nonen, S; Okugawa, G; Sakai, S; Serretti, A; Sunada, N; Takekita, Y; Wakeno, M | 3 |
| Abe, K; Akagi, T; Matoba, M; Mawatari, H; Saito, O; Syuuto, C; Tagami, K; Takeno, N | 1 |
| Arakawa, R; Kanamitsu, K; Kusuhara, H; Sugiyama, Y; Suhara, T | 1 |
| Bundo, M; Iwamoto, K; Kasai, K; Murata, Y; Sunaga, F | 1 |
| Chiba, K; Goto, A; Hagiwara-Nagasawa, M; Izumi-Nakaseko, H; Kambayashi, R; Matsumoto, A; Naito, AT; Sugiyama, A | 1 |
| Hara, K; Haranishi, Y; Terada, T | 1 |
| Bhansali, A; Chauhan, AS; Gupta, A; Jain, S; Jyani, G; Kaur, G; Lakshmi, P; Muniyandi, M; Nagarajan, K; Prinja, S; Rastogi, A; Selvam, JM; Teerawattananon, Y | 1 |
| Inoue, S; Maeda, I; Ogawa, A; Terada, S; Yamada, N; Yoshiuchi, K | 1 |
| Miyazaki, K | 1 |
9 review(s) available for perospirone and thiazoles
| Article | Year |
|---|---|
Potential role of 5-HT2 and D2 receptor interaction in the atypical antipsychotic action of the novel succimide derivative, perospirone.
Topics: Animals; Antipsychotic Agents; Corpus Striatum; Disease Models, Animal; Dopamine Antagonists; Gene Expression Regulation; Indoles; Isoindoles; Mood Disorders; Rats; Receptors, Dopamine D2; Receptors, Serotonin; Serotonin Antagonists; Thiazoles | 1997 |
[Pharmacological characteristics of perospirone hydrochloride, a novel antipsychotic agent].
Topics: Animals; Antipsychotic Agents; Basal Ganglia Diseases; Clinical Trials as Topic; Humans; Indoles; Isoindoles; Schizophrenia; Serotonin Antagonists; Thiazoles | 2000 |
Perospirone.
Topics: Animals; Antipsychotic Agents; Clinical Trials as Topic; Humans; Indoles; Isoindoles; Psychiatric Status Rating Scales; Schizophrenia; Thiazoles; Treatment Outcome | 2001 |
Perospirone (Sumitomo Pharmaceuticals).
Topics: Animals; Clinical Trials as Topic; Dopamine Antagonists; Humans; Indoles; Isoindoles; Schizophrenia; Serotonin Antagonists; Technology, Pharmaceutical; Thiazoles | 2002 |
[An introduction to antipsychotics].
Topics: Antipsychotic Agents; Benzodiazepines; Dibenzothiazepines; Dopamine Antagonists; Humans; Indoles; Isoindoles; Olanzapine; Pirenzepine; Quetiapine Fumarate; Receptors, Dopamine; Receptors, Serotonin; Risperidone; Schizophrenia; Serotonin Antagonists; Thiazoles | 2003 |
[Extrapyramidal syndrome].
Topics: Acute Disease; Akathisia, Drug-Induced; Antipsychotic Agents; Basal Ganglia Diseases; Dibenzothiazepines; Dopamine D2 Receptor Antagonists; Dystonia; Humans; Indoles; Isoindoles; Parkinsonian Disorders; Quetiapine Fumarate; Receptors, Muscarinic; Receptors, Serotonin; Risperidone; Serotonin Antagonists; Syndrome; Thiazoles | 2003 |
Pharmacokinetics and metabolism update for some recent antipsychotics.
Topics: Animals; Antipsychotic Agents; Aripiprazole; Drug Interactions; Humans; Inactivation, Metabolic; Isoindoles; Lurasidone Hydrochloride; Piperazines; Quinolones; Thiazoles | 2011 |
Efficacy and tolerability of perospirone in schizophrenia: a systematic review and meta-analysis of randomized controlled trials.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antipsychotic Agents; Female; Humans; Isoindoles; Male; Middle Aged; Randomized Controlled Trials as Topic; Schizophrenia; Thiazoles; Young Adult | 2013 |
Cardiometabolic risks of blonanserin and perospirone in the management of schizophrenia: a systematic review and meta-analysis of randomized controlled trials.
Topics: Adult; Antipsychotic Agents; Blood Glucose; Double-Blind Method; Glycated Hemoglobin; Heart; Humans; Isoindoles; Piperazines; Piperidines; Randomized Controlled Trials as Topic; Risk; Schizophrenia; Thiazoles; Weight Gain | 2014 |
22 trial(s) available for perospirone and thiazoles
| Article | Year |
|---|---|
Prolactin levels in schizophrenic patients receiving perospirone in comparison to risperidone.
Topics: Antipsychotic Agents; Dose-Response Relationship, Drug; Female; Humans; Indoles; Isoindoles; Male; Middle Aged; Prolactin; Risperidone; Schizophrenia; Thiazoles | 2003 |
A novel antipsychotic, perospirone, has antiserotonergic and antidopaminergic effects in human brain: findings from neuroendocrine challenge tests.
Topics: Adult; Affect; Antipsychotic Agents; Area Under Curve; Brain; Dopamine Antagonists; Double-Blind Method; Female; Humans; Hydrocortisone; Indoles; Isoindoles; Male; Neurosecretory Systems; Prolactin; Serotonin Antagonists; Thiazoles; Vision Disorders | 2004 |
Steady-state pharmacokinetics of a new antipsychotic agent perospirone and its active metabolite, and its relationship with prolactin response.
Topics: Adult; Aged; Antipsychotic Agents; Area Under Curve; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Female; Humans; Immunoenzyme Techniques; Indoles; Isoindoles; Male; Middle Aged; Prolactin; Schizophrenia; Thiazoles; Time Factors | 2004 |
Effects of changing from typical to atypical antipsychotic drugs on subjective sleep quality in patients with schizophrenia in a Japanese population.
Topics: Adult; Aged; Antipsychotic Agents; Benzodiazepines; Dibenzothiazepines; Drug Administration Schedule; Female; Health Status; Hospitalization; Humans; Indoles; Isoindoles; Japan; Male; Middle Aged; Olanzapine; Psychiatric Status Rating Scales; Quetiapine Fumarate; Regression Analysis; Risperidone; Schizophrenia; Schizophrenic Psychology; Severity of Illness Index; Sleep; Thiazoles | 2004 |
Influence of aging on the improvement of subjective sleep quality by atypical antipsychotic drugs in patients with schizophrenia: comparison of middle-aged and older adults.
Topics: Adult; Age Factors; Aged; Aged, 80 and over; Antipsychotic Agents; Benzodiazepines; Dibenzothiazepines; Female; Humans; Indoles; Isoindoles; Male; Middle Aged; Olanzapine; Polysomnography; Psychiatric Status Rating Scales; Quetiapine Fumarate; Risperidone; Schizophrenia; Schizophrenic Psychology; Sleep Initiation and Maintenance Disorders; Sleep Stages; Thiazoles | 2005 |
Perospirone in the treatment of schizophrenia: effect on verbal memory organization.
Topics: Adult; Aged; Antipsychotic Agents; Female; Humans; Indoles; Isoindoles; Male; Memory; Middle Aged; Neuropsychological Tests; Psychiatric Status Rating Scales; Schizophrenia; Schizophrenic Psychology; Statistics, Nonparametric; Thiazoles; Verbal Learning | 2006 |
Effects of itraconazole and tandospirone on the pharmacokinetics of perospirone.
Topics: Adult; Analysis of Variance; Antifungal Agents; Antipsychotic Agents; Area Under Curve; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Drug Interactions; Half-Life; Humans; Indoles; Isoindoles; Itraconazole; Male; Middle Aged; Piperazines; Pyrimidines; Serotonin Receptor Agonists; Thiazoles | 2006 |
Efficacy of perospirone in the management of aggressive behavior associated with dementia.
Topics: Aged; Aged, 80 and over; Aggression; Antipsychotic Agents; Dementia; Dose-Response Relationship, Drug; Female; Humans; Indoles; Isoindoles; Male; Retrospective Studies; Thiazoles; Time Factors | 2006 |
Effect of carbamazepine on the single oral dose pharmacokinetics of perospirone and its active metabolite.
Topics: Administration, Oral; Adult; Anticonvulsants; Antipsychotic Agents; Carbamazepine; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Drug Interactions; Enzyme Activation; Humans; Immunoenzyme Techniques; Indoles; Isoindoles; Male; Middle Aged; Prolactin; Thiazoles | 2006 |
The effect of perospirone on auditory P300 in schizophrenia: a preliminary study.
Topics: Adult; Antipsychotic Agents; Cognition Disorders; Data Interpretation, Statistical; Electrophysiology; Event-Related Potentials, P300; Evoked Potentials, Auditory; Female; Humans; Indoles; Isoindoles; Male; Middle Aged; Psychiatric Status Rating Scales; Schizophrenia; Schizophrenic Psychology; Thiazoles | 2006 |
Perospirone is a new generation antipsychotic: evidence from a positron emission tomography study of serotonin 2 and D2 receptor occupancy in the living human brain.
Topics: Adult; Antipsychotic Agents; Binding, Competitive; Brain; Humans; Indoles; Isoindoles; Male; Positron-Emission Tomography; Raclopride; Radiopharmaceuticals; Receptors, Dopamine D2; Receptors, Serotonin, 5-HT2; Reference Values; Spiperone; Thiazoles | 2006 |
Perospirone in the treatment of patients with delirium.
Topics: Aged; Antipsychotic Agents; Delirium; Female; Humans; Indoles; Isoindoles; Male; Psychiatric Status Rating Scales; Thiazoles | 2007 |
A pharmaco-EEG study on antipsychotic drugs in healthy volunteers.
Topics: Adult; Antipsychotic Agents; Benzodiazepines; Chlorpromazine; Cross-Over Studies; Dibenzothiazepines; Electroencephalography; Fourier Analysis; Haloperidol; Humans; Indoles; Isoindoles; Male; Olanzapine; Quetiapine Fumarate; Reference Values; Risperidone; Single-Blind Method; Thiazoles; Time Factors | 2007 |
Determination of azelnidipine by LC-ESI-MS and its application to a pharmacokinetic study in healthy Chinese volunteers.
Topics: Adult; Antipsychotic Agents; Azetidinecarboxylic Acid; Calcium Channel Blockers; Chromatography, High Pressure Liquid; Dihydropyridines; Female; Humans; Isoindoles; Male; Reference Standards; Reproducibility of Results; Spectrometry, Mass, Electrospray Ionization; Thiazoles | 2008 |
Augmentation of antidepressants with perospirone for treatment-resistant major depressive disorder.
Topics: Adult; Aged; Analysis of Variance; Antidepressive Agents; Antipsychotic Agents; Depressive Disorder, Major; Drug Synergism; Female; Humans; Isoindoles; Male; Middle Aged; Outpatients; Psychiatric Status Rating Scales; Retrospective Studies; Thiazoles; Time Factors | 2009 |
Effect of perospirone on P300 electrophysiological activity and social cognition in schizophrenia: a three-dimensional analysis with sloreta.
Topics: Adult; Antipsychotic Agents; Brain Mapping; Cognition; Event-Related Potentials, P300; Female; Frontal Lobe; Functional Laterality; Humans; Image Processing, Computer-Assisted; Imaging, Three-Dimensional; Isoindoles; Magnetoencephalography; Male; Memory; Middle Aged; Neuropsychological Tests; Outpatients; Psychiatric Status Rating Scales; Schizophrenia; Schizophrenic Psychology; Social Perception; Thiazoles; Verbal Learning; Young Adult | 2009 |
Randomized clinical comparison of perospirone and risperidone in patients with schizophrenia: Kansai Psychiatric Multicenter Study.
Topics: Adolescent; Adult; Aged; Antipsychotic Agents; Basal Ganglia Diseases; Female; Humans; Isoindoles; Male; Middle Aged; Psychiatric Status Rating Scales; Risperidone; Schizophrenia; Schizophrenic Psychology; Thiazoles | 2009 |
An unblinded comparison of the clinical and cognitive effects of switching from first-generation antipsychotics to aripiprazole, perospirone or olanzapine in patients with chronic schizophrenia.
Topics: Adult; Aged; Antipsychotic Agents; Aripiprazole; Attention; Benzodiazepines; Chronic Disease; Cognition Disorders; Dose-Response Relationship, Drug; Drug Substitution; Executive Function; Female; Humans; Isoindoles; Longitudinal Studies; Male; Memory; Middle Aged; Neuropsychological Tests; Olanzapine; Piperazines; Psychiatric Status Rating Scales; Quinolones; Schizophrenia; Single-Blind Method; Thiazoles; Time Factors; Verbal Learning | 2011 |
A 12-week randomized, open-label study of perospirone versus aripiprazole in the treatment of Japanese schizophrenia patients.
Topics: Adolescent; Adult; Aged; Antipsychotic Agents; Aripiprazole; Female; Humans; Isoindoles; Japan; Male; Middle Aged; Piperazines; Quinolones; Schizophrenia; Severity of Illness Index; Thiazoles; Treatment Outcome | 2013 |
HTR1A Gene Polymorphisms and 5-HT1A Receptor Partial Agonist Antipsychotics Efficacy in Schizophrenia.
Topics: Adult; Antipsychotic Agents; Aripiprazole; Female; Haplotypes; Humans; Isoindoles; Male; Middle Aged; Polymorphism, Single Nucleotide; Receptor, Serotonin, 5-HT1A; Schizophrenia; Serotonin 5-HT1 Receptor Agonists; Thiazoles; Treatment Outcome | 2015 |
Antagonist and partial agonist at the dopamine D2 receptors in drug-naïve and non-drug-naïve schizophrenia: a randomized, controlled trial.
Topics: Adult; Aged; Akathisia, Drug-Induced; Antipsychotic Agents; Aripiprazole; Basal Ganglia Diseases; Dopamine Agonists; Dopamine D2 Receptor Antagonists; Drug Partial Agonism; Female; Humans; Isoindoles; Male; Middle Aged; Receptors, Dopamine D2; Schizophrenia; Schizophrenic Psychology; Thiazoles; Treatment Outcome; Young Adult | 2015 |
Serotonin 7 Receptor Variants Are Not Associated with Response to Second-Generation Antipsychotics in Japanese Schizophrenia Patients.
Topics: Adult; Antipsychotic Agents; Aripiprazole; Asian People; Female; Humans; Isoindoles; Japan; Linkage Disequilibrium; Male; Middle Aged; Polymorphism, Single Nucleotide; Precision Medicine; Psychiatric Status Rating Scales; Receptors, Serotonin; Schizophrenia; Thiazoles; Treatment Outcome | 2015 |
67 other study(ies) available for perospirone and thiazoles
| Article | Year |
|---|---|
Pharmacological actions of SM-9018, a new neuroleptic drug with both potent 5-hydroxytryptamine2 and dopamine2 antagonistic actions.
Topics: Animals; Antipsychotic Agents; Behavior, Animal; Brain Chemistry; Catalepsy; Dopamine Antagonists; Indoles; Isoindoles; Ketanserin; Male; Methamphetamine; Mice; Mice, Inbred Strains; Motor Activity; Norepinephrine; Parasympatholytics; Psychomotor Performance; Rats; Rats, Inbred Strains; Serotonin Antagonists; Spiperone; Stereotyped Behavior; Thiazoles | 1990 |
Binding profile of SM-9018, a novel antipsychotic candidate.
Topics: Animals; Antipsychotic Agents; Brain; Dopamine Antagonists; Indoles; Isoindoles; Male; Membranes; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Dopamine D1; Receptors, Dopamine D2; Receptors, Serotonin; Thiazoles | 1990 |
Effects of chronic treatments with SM-9018, a potential atypical neuroleptic, on behavioral dopaminergic and serotonergic sensitivities in rats.
Topics: 5-Hydroxytryptophan; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Antipsychotic Agents; Apomorphine; Behavior, Animal; Dopamine; Haloperidol; Indoles; Isoindoles; Male; Motor Activity; Posture; Rats; Rats, Sprague-Dawley; Serotonin; Stereotyped Behavior; Thiazoles | 1995 |
Evaluation of bradykinesia induction by SM-9018, a novel 5-HT2 and D2 receptor antagonist, using the mouse pole test.
Topics: Animals; Antipsychotic Agents; Catalepsy; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Dyskinesia, Drug-Induced; Indoles; Isoindoles; Male; Mice; Mice, Inbred Strains; Psychomotor Performance; Serotonin Antagonists; Thiazoles | 1994 |
Effects of SM-9018, a potential atypical neuroleptic, on the central monoaminergic system in rats.
Topics: Animals; Antipsychotic Agents; Biogenic Monoamines; Brain Chemistry; Chromatography, High Pressure Liquid; Dopamine; Electrochemistry; Haloperidol; In Vitro Techniques; Indoles; Isoindoles; Kinetics; Male; Norepinephrine; Rats; Rats, Sprague-Dawley; Serotonin; Thiazoles | 1993 |
Succinimide derivatives. II. Synthesis and antipsychotic activity of N-[4-[4-(1,2-benzisothiazol-3-yl)-1-piperazinyl]butyl]-1,2-cis- cyclohexanedicarboximide (SM-9018) and related compounds.
Topics: Animals; Antipsychotic Agents; Behavior, Animal; Catalepsy; Central Nervous System Depressants; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Haloperidol; In Vitro Techniques; Indoles; Isoindoles; Mice; Motor Activity; Neostriatum; Psychotropic Drugs; Rats; Serotonin Antagonists; Spiro Compounds; Stereotyped Behavior; Structure-Activity Relationship; Succinimides; Thiazoles | 1995 |
Effects of subchronic treatments with SM-9018, a novel 5-HT2 and D2 antagonist, on dopamine and 5-HT receptors in rats.
Topics: Animals; Antipsychotic Agents; Binding, Competitive; Haloperidol; Indoles; Isoindoles; Male; Raclopride; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D2; Receptors, Serotonin; Salicylamides; Serotonin Antagonists; Thiazoles; Up-Regulation | 1995 |
Contrasting effects of SM-9018, a potential atypical antipsychotic, and haloperidol on c-fos mRNA expression in the rat striatum.
Topics: Animals; Antipsychotic Agents; Corpus Striatum; Gene Expression; Genes, fos; Haloperidol; Indoles; Isoindoles; Male; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; RNA, Messenger; Serotonin Antagonists; Thiazoles | 1996 |
Evaluation of perospirone (SM-9018), a novel serotonin-2 and dopamine-2 receptor antagonist, and other antipsychotics in the conditioned fear stress-induced freezing behavior model in rats.
Topics: Animals; Antipsychotic Agents; Clozapine; Dopamine Antagonists; Fear; Indoles; Isoindoles; Male; Rats; Rats, Sprague-Dawley; Risperidone; Serotonin Antagonists; Thiazoles | 1996 |
Effects of SM-9018, a novel 5-HT2 and D2 receptor antagonist, on electrically-evoked [3H]acetylcholine release from rat striatal slices.
Topics: Acetylcholine; Animals; Antipsychotic Agents; Dopamine Agonists; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Electric Stimulation; Haloperidol; In Vitro Techniques; Indoles; Isoindoles; Male; Neostriatum; Quinpirole; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D2; Serotonin Antagonists; Thiazoles | 1996 |
Effects of perospirone (SM-9018), a potential atypical neuroleptic, on dopamine D1 receptor-mediated vacuous chewing movement in rats: a role of 5-HT2 receptor blocking activity.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Antipsychotic Agents; Avoidance Learning; Dopamine Agonists; Dopamine Antagonists; Dyskinesia, Drug-Induced; Haloperidol; Indoles; Isoindoles; Male; Mastication; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, Dopamine D2; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Antagonists; Thiazoles | 1997 |
Effects of perospirone, a novel antipsychotic agent, on the dopaminergic neurons in the rat ventral tegmental area.
Topics: Animals; Antipsychotic Agents; Dopamine; Electrophysiology; Indoles; Isoindoles; Male; Methamphetamine; Neurons; Rats; Rats, Wistar; Thiazoles; Ventral Tegmental Area | 1997 |
Localization and pharmacological characterization of [3H]perospirone-binding sites in rat brain.
Topics: Animals; Antipsychotic Agents; Benzazepines; Binding Sites; Brain; Domperidone; Dopamine Antagonists; Indoles; Isoindoles; Ketanserin; Male; Membranes; Radioligand Assay; Rats; Rats, Sprague-Dawley; Serotonin Antagonists; Thiazoles; Tritium | 1998 |
In vivo occupation of dopamine D1, D2 and serotonin2A receptors by novel antipsychotic drug, SM-9018 and its metabolite, in rat brain.
Topics: Animals; Antipsychotic Agents; Binding, Competitive; Brain Chemistry; Dopamine Antagonists; Indoles; Isoindoles; Male; Quinolines; Radioligand Assay; Rats; Rats, Wistar; Receptors, Dopamine D1; Receptors, Dopamine D2; Receptors, Serotonin; Thiazoles | 1998 |
Anxiolytic-like effects of perospirone, a novel serotonin-2 and dopamine-2 antagonist (SDA)-type antipsychotic agent.
Topics: Aggression; Animals; Anti-Anxiety Agents; Antipsychotic Agents; Diazepam; Dopamine Antagonists; Dose-Response Relationship, Drug; Haloperidol; Indoles; Interpersonal Relations; Isoindoles; Male; Rats; Serotonin Antagonists; Thiazoles | 1998 |
Effects of perospirone, a novel 5-HT2 and D2 receptor antagonist, on Fos protein expression in the rat forebrain.
Topics: Animals; Antipsychotic Agents; Brain Chemistry; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Gene Expression Regulation; Immunohistochemistry; Indoles; Isoindoles; Male; Neostriatum; Nucleus Accumbens; Prosencephalon; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2A; Receptors, Serotonin; Serotonin Antagonists; Thiazoles | 1999 |
Perospirone. SM 9018.
Topics: Animals; Antipsychotic Agents; Clinical Trials as Topic; Dopamine Antagonists; Drugs, Investigational; Humans; Indoles; Isoindoles; Serotonin Antagonists; Thiazoles | 1999 |
Perospirone. SM 9018.
Topics: Antipsychotic Agents; Clinical Trials as Topic; Humans; Indoles; Isoindoles; Thiazoles | 1999 |
Differential effects of subchronic treatments with atypical antipsychotic drugs on dopamine D2 and serotonin 5-HT2A receptors in the rat brain.
Topics: Animals; Antipsychotic Agents; Benzodiazepines; Brain Chemistry; Chlorpromazine; Dopamine Antagonists; Dose-Response Relationship, Drug; Humans; Indoles; Isoindoles; Male; Olanzapine; Pirenzepine; Protein Binding; Quinolines; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT2A; Receptors, Dopamine D2; Receptors, Serotonin; Risperidone; Selective Serotonin Reuptake Inhibitors; Thiazoles | 2000 |
Determination of a new atypical antipsychotic agent perospirone and its metabolite in human plasma by automated column-switching high-performance liquid chromatography.
Topics: Administration, Oral; Antipsychotic Agents; Automation; Chromatography, High Pressure Liquid; Humans; Indoles; Isoindoles; Reference Standards; Reproducibility of Results; Sensitivity and Specificity; Spectrometry, Fluorescence; Thiazoles | 2003 |
Perospirone, a novel antipsychotic agent, hyperpolarizes rat dorsal raphe neurons via 5-HT1A receptor.
Topics: Animals; Antipsychotic Agents; Dose-Response Relationship, Drug; Indoles; Isoindoles; Membrane Potentials; Neurons; Raphe Nuclei; Rats; Receptor, Serotonin, 5-HT1A; Thiazoles | 2003 |
[Perospirone therapy in elderly patients with schizophrenia].
Topics: Aged; Antipsychotic Agents; Female; Humans; Indoles; Isoindoles; Male; Schizophrenia; Thiazoles | 2003 |
Two cases of perospirone-induced mania in schizophrenia.
Topics: Adolescent; Adult; Antipsychotic Agents; Bipolar Disorder; Female; Humans; Indoles; Isoindoles; Male; Schizophrenia; Thiazoles | 2004 |
Use of perospirone for obesity and diabetes mellitus in patients with schizophrenia: three case reports.
Topics: Adult; Antipsychotic Agents; Diabetes Mellitus, Type 2; Humans; Indoles; Isoindoles; Male; Middle Aged; Obesity; Schizophrenia; Thiazoles; Weight Gain | 2004 |
Perospirone, a novel atypical antipsychotic drug, potentiates fluoxetine-induced increases in dopamine levels via multireceptor actions in the rat medial prefrontal cortex.
Topics: Animals; Antidepressive Agents, Second-Generation; Antipsychotic Agents; Chromatography, High Pressure Liquid; Dopamine; Dose-Response Relationship, Drug; Drug Synergism; Electrochemistry; Fluoxetine; Indoles; Isoindoles; Male; Piperazines; Prefrontal Cortex; Pyridines; Rats; Rats, Wistar; Serotonin Antagonists; Thiazoles | 2004 |
Effects of serotonin-dopamine antagonists on prepulse inhibition and neurotransmitter contents in the rat cortex.
Topics: Animals; Antipsychotic Agents; Cerebral Cortex; Cognition; Dopamine; Dopamine Antagonists; Haloperidol; Indoles; Isoindoles; Male; Neurotransmitter Agents; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Reflex, Startle; Risperidone; Serotonin; Serotonin Antagonists; Thiazoles | 2004 |
Characterization of human cytochrome P450 enzymes involved in the in vitro metabolism of perospirone.
Topics: Antibodies, Monoclonal; Antipsychotic Agents; Carbon Radioisotopes; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Humans; Indoles; Isoenzymes; Isoindoles; Ketoconazole; Male; Microsomes, Liver; Models, Chemical; Quercetin; Quinidine; Thiazoles | 2005 |
Efficacy of carbamazepine against neuroleptic-induced akathisia in treatment with perospirone: case series.
Topics: Adult; Akathisia, Drug-Induced; Anticonvulsants; Antipsychotic Agents; Carbamazepine; Drug Combinations; Female; Humans; Indoles; Isoindoles; Male; Schizophrenia, Paranoid; Thiazoles | 2005 |
[Treatment of "the premonitory state of schizophrenia" with atypical antipsychotics].
Topics: Adult; Antipsychotic Agents; Benzodiazepines; Female; Humans; Indoles; Isoindoles; Male; Middle Aged; Olanzapine; Risperidone; Schizophrenia; Thiazoles | 2004 |
Perospirone improves food refusal in elderly patients with mental disorders.
Topics: Aged; Aged, 80 and over; Eating; Female; Humans; Indoles; Isoindoles; Male; Mental Disorders; Middle Aged; Thiazoles | 2005 |
Perospirone for treatment of dissociative identity disorder.
Topics: Adult; Antipsychotic Agents; Anxiety; Dissociative Identity Disorder; Female; Hallucinations; Humans; Indoles; Isoindoles; Thiazoles | 2005 |
Perospirone, a novel antipsychotic drug, inhibits marble-burying behavior via 5-HT1A receptor in mice: implications for obsessive-compulsive disorder.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Antipsychotic Agents; Behavior, Animal; Disease Models, Animal; Dose-Response Relationship, Drug; Haloperidol; Indoles; Isoindoles; Male; Mice; Mice, Inbred ICR; Motor Activity; Obsessive-Compulsive Disorder; Piperazines; Receptor, Serotonin, 5-HT1A; Risperidone; Serotonin Antagonists; Serotonin Receptor Agonists; Thiazoles | 2005 |
Neuroleptic malignant syndrome induced by perospirone.
Topics: Antipsychotic Agents; Female; Humans; Indoles; Isoindoles; Middle Aged; Neuroleptic Malignant Syndrome; Thiazoles | 2006 |
Beneficial effects of perospirone on aggressive behavior associated with dementia.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Antipsychotic Agents; Dementia, Vascular; Dose-Response Relationship, Drug; Female; Follow-Up Studies; Humans; Indoles; Isoindoles; Mental Status Schedule; Psychomotor Agitation; Thiazoles; Treatment Outcome | 2006 |
Neuroleptic malignant syndrome related to a switch to perospirone and anticholinergic withdrawal.
Topics: Adult; Antipsychotic Agents; Cholinergic Antagonists; Drug Therapy, Combination; Humans; Indoles; Isoindoles; Male; Neuroleptic Malignant Syndrome; Schizophrenia, Paranoid; Substance Withdrawal Syndrome; Thiazoles | 2006 |
Effective treatment of coprophagia in a patient with schizophrenia with the novel atypical antipsychotic drug perospirone.
Topics: Antipsychotic Agents; Brain; Follow-Up Studies; Human Coprophagia; Humans; Indoles; Isoindoles; Male; Middle Aged; Receptor, Serotonin, 5-HT1A; Schizophrenic Psychology; Thiazoles; Treatment Outcome | 2006 |
Perospirone in treatment of Huntington's disease: a first case report.
Topics: Aged; Antipsychotic Agents; Anxiety; Dopamine Antagonists; Female; Humans; Huntington Disease; Indoles; Isoindoles; Mental Disorders; Neuropsychological Tests; Serotonin Antagonists; Thiazoles | 2007 |
Determination of perospirone by liquid chromatography/electrospray mass spectrometry: application to a pharmacokinetic study in healthy Chinese volunteers.
Topics: Adult; Antipsychotic Agents; Asian People; China; Chromatography, Liquid; Female; Humans; Indoles; Isoindoles; Male; Molecular Structure; Reproducibility of Results; Spectrometry, Mass, Electrospray Ionization; Thiazoles | 2007 |
Perospirone augmentation of paroxetine in treatment of refractory obsessive-compulsive disorder with depression.
Topics: Antidepressive Agents, Second-Generation; Antipsychotic Agents; Depression; Drug Synergism; Female; Humans; Indoles; Isoindoles; Middle Aged; Obsessive-Compulsive Disorder; Paroxetine; Thiazoles | 2007 |
Ultra-performance liquid chromatography-tandem mass spectrometry for the determination of atypical antipsychotics and some metabolites in in vitro samples.
Topics: Antipsychotic Agents; Aripiprazole; Chromatography, High Pressure Liquid; Dibenzothiazepines; Indoles; Isoindoles; Piperazines; Quetiapine Fumarate; Quinolones; Reference Standards; Reproducibility of Results; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry; Thiazoles | 2007 |
Alteration in serum neural cell adhesion molecule in patients of schizophrenia.
Topics: Adult; Age Factors; Antipsychotic Agents; Benzodiazepines; Blotting, Western; Chronic Disease; Dibenzothiazepines; Female; Humans; Indoles; Isoindoles; Male; Middle Aged; Molecular Weight; Neural Cell Adhesion Molecules; Olanzapine; Protein Isoforms; Quetiapine Fumarate; Risperidone; Schizophrenia; Thiazoles | 2007 |
New-onset diabetic ketoacidosis induced by the addition of perospirone hydrochloride in a patient treated with risperidone.
Topics: Adult; Diabetic Ketoacidosis; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Follow-Up Studies; Humans; Indoles; Isoindoles; Male; Risk Assessment; Risperidone; Schizophrenia; Severity of Illness Index; Thiazoles; Treatment Outcome | 2007 |
[Pharmacokinetics of perospirone hydrochloride at an excessive dose and changes in the serum prolactin level].
Topics: Adult; Antipsychotic Agents; Chromatography, High Pressure Liquid; Consciousness Disorders; Enzyme-Linked Immunosorbent Assay; Female; Humans; Indoles; Isoindoles; Prolactin; Schizophrenia; Thiazoles; Time Factors | 2007 |
Effective adjunctive use of tandospirone with perospirone for enhancing verbal memory and quality of life in schizophrenia.
Topics: Adult; Anti-Anxiety Agents; Antipsychotic Agents; Follow-Up Studies; Humans; Indoles; Isoindoles; Male; Memory; Piperazines; Pyrimidines; Quality of Life; Schizophrenia; Schizophrenic Psychology; Thiazoles; Verbal Behavior | 2007 |
The effect of atypical antipsychotics, perospirone, ziprasidone and quetiapine on microglial activation induced by interferon-gamma.
Topics: Animals; Antipsychotic Agents; Cell Survival; Cells, Cultured; Dibenzothiazepines; Dose-Response Relationship, Drug; Drug Interactions; Interferon-gamma; Isoindoles; Mice; Mice, Inbred C57BL; Microglia; Nitrites; Piperazines; Quetiapine Fumarate; Rats; Tetrazolium Salts; Thiazoles | 2008 |
Long-term perospirone treatment with a single dose at bedtime in schizophrenia: relevant to intermittent dopamine D2 receptor antagonism.
Topics: Adult; Ambulatory Care; Antipsychotic Agents; Chromatography, High Pressure Liquid; Dopamine D2 Receptor Antagonists; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Follow-Up Studies; Humans; Indoles; Isoindoles; Longitudinal Studies; Male; Middle Aged; Schizophrenia; Schizophrenic Psychology; Secondary Prevention; Thiazoles; Treatment Outcome | 2008 |
Phencyclidine-induced cognitive deficits in mice are improved by subsequent subchronic administration of the antipsychotic drug perospirone: role of serotonin 5-HT1A receptors.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Analysis of Variance; Animals; Antipsychotic Agents; Behavior, Animal; Body Temperature; Cognition Disorders; Dose-Response Relationship, Drug; Drug Interactions; Injections, Subcutaneous; Isoindoles; Male; Mice; Mice, Inbred ICR; Pattern Recognition, Visual; Phencyclidine; Piperazines; Protein Binding; Pyridines; Receptor, Serotonin, 5-HT1A; Serotonin Antagonists; Serotonin Receptor Agonists; Thiazoles; Time Factors | 2008 |
[Usefulness of perospirone for the prevention of nausea related to opioid administration].
Topics: Aged; Aged, 80 and over; Analgesics, Opioid; Female; Humans; Isoindoles; Male; Middle Aged; Nausea; Retrospective Studies; Thiazoles | 2008 |
Effect of the novel antipsychotic drug perospirone on P-glycoprotein function and expression in Caco-2 cells.
Topics: Antipsychotic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Base Sequence; Caco-2 Cells; Cell Line, Tumor; DNA Primers; Humans; Isoindoles; Reverse Transcriptase Polymerase Chain Reaction; Rhodamine 123; RNA, Messenger; Thiazoles | 2008 |
Dopamine D2 receptor occupancy by perospirone: a positron emission tomography study in patients with schizophrenia and healthy subjects.
Topics: Adult; Antipsychotic Agents; Binding, Competitive; Brain; Case-Control Studies; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Female; Humans; Isoindoles; Magnetic Resonance Imaging; Male; Positron-Emission Tomography; Raclopride; Receptors, Dopamine D2; Schizophrenia; Thiazoles; Time Factors | 2010 |
The wide variability of perospirone metabolism and the effect of perospirone on prolactin in psychiatric patients.
Topics: Adult; Aged; Antipsychotic Agents; Chromatography, High Pressure Liquid; Female; Humans; Immunoenzyme Techniques; Individuality; Indoles; Isoindoles; Male; Middle Aged; Prolactin; Schizophrenia; Thiazoles | 2010 |
Prolactin fluctuation over the course of a day during treatments with three atypical antipsychotics in schizophrenic patients.
Topics: Adult; Antipsychotic Agents; Benzodiazepines; Circadian Rhythm; Drug Administration Schedule; Drug Monitoring; Female; Humans; Hyperprolactinemia; Isoindoles; Male; Middle Aged; Olanzapine; Prolactin; Risperidone; Schizophrenia; Thiazoles; Time Factors; Treatment Outcome | 2010 |
A case of schizophrenia with Meige syndrome induced by long-term aripiprazole successfully treated with perospirone.
Topics: Antipsychotic Agents; Aripiprazole; Female; Humans; Isoindoles; Meige Syndrome; Piperazines; Quinolones; Schizophrenia; Thiazoles; Young Adult | 2011 |
Mirtazapine in combination with perospirone synergistically enhances dopamine release in the rat prefrontal cortex via 5-HT1A receptor activation.
Topics: Animals; Depression; Disease Models, Animal; Dopamine; Drug Resistance; Drug Synergism; Drug Therapy, Combination; Isoindoles; Male; Mianserin; Microdialysis; Mirtazapine; Piperazines; Prefrontal Cortex; Pyridines; Rats; Rats, Wistar; Serotonin; Serotonin 5-HT1 Receptor Agonists; Thiazoles | 2011 |
Improvement in QTc prolongation induced by zotepine following a switch to perospirone.
Topics: Antipsychotic Agents; Dibenzothiepins; Electrocardiography; Female; Haloperidol; Heart Rate; Humans; Isoindoles; Long QT Syndrome; Middle Aged; Schizophrenia; Thiazoles; Water-Electrolyte Imbalance | 2012 |
State and trait markers of emotionally charged visual event-related potentials (P300) in drug-naïve schizophrenia.
Topics: Adolescent; Adult; Antipsychotic Agents; Benzodiazepines; Case-Control Studies; Emotions; Event-Related Potentials, P300; Evoked Potentials, Visual; Facial Expression; Female; Humans; Isoindoles; Male; Olanzapine; Photic Stimulation; Psychomotor Performance; Reaction Time; Risperidone; Schizophrenia; Schizophrenic Psychology; Thiazoles | 2012 |
Perospirone normalized P300 and cognitive function in a case of early psychosis.
Topics: Adolescent; Antipsychotic Agents; Cognition Disorders; Event-Related Potentials, P300; Humans; Isoindoles; Male; Schizophrenia; Thiazoles; Treatment Outcome | 2013 |
A case of schizophrenia with meige syndrome induced by perospirone successfully treated with biperiden.
Topics: Adult; Antiparkinson Agents; Antipsychotic Agents; Biperiden; Female; Humans; Isoindoles; Lymphedema; Schizophrenia; Thiazoles | 2013 |
[A study on the antiemetic effect and extrapyramidal symptoms of prochlorperazine versus perospirone for the control of nausea and vomiting due to opioid introduction].
Topics: Antiemetics; Basal Ganglia Diseases; Female; Humans; Isoindoles; Male; Middle Aged; Nausea; Neoplasms; Opioid-Related Disorders; Palliative Care; Prochlorperazine; Retrospective Studies; Thiazoles; Vomiting | 2013 |
Perospirone Exhibits Antiemetic Efficacy against Opioid-Induced Nausea in Patients with Advanced Cancer.
Topics: Analgesics, Opioid; Antiemetics; Antipsychotic Agents; Female; Humans; Isoindoles; Japan; Male; Nausea; Neoplasms; Pain; Retrospective Studies; Thiazoles | 2015 |
Prediction of CNS occupancy of dopamine D2 receptor based on systemic exposure and in vitro experiments.
Topics: Adult; Animals; Antipsychotic Agents; Brain; Computer Simulation; Dopamine D2 Receptor Antagonists; Humans; Isoindoles; Kinetics; Male; Mice, Inbred ICR; Positron-Emission Tomography; Quetiapine Fumarate; Raclopride; Receptors, Dopamine D2; Thiazoles; Young Adult | 2016 |
DNA Methylation Profiling in a Neuroblastoma Cell Line Exposed to the Antipsychotic Perospirone.
Topics: Antipsychotic Agents; Cell Line, Tumor; DNA Methylation; Epigenesis, Genetic; Gene Expression Profiling; Humans; Isoindoles; Japan; Neuroblastoma; Oligonucleotide Array Sequence Analysis; Thiazoles | 2019 |
Experimental analysis of the onset mechanism of TdP reported in an LQT3 patient during pharmacological treatment with serotonin-dopamine antagonists against insomnia and nocturnal delirium.
Topics: Action Potentials; Anesthetics, Inhalation; Animals; Calcium Channel Agonists; Cardiac Conduction System Disease; Delirium; Dogs; Dopamine Antagonists; Dose-Response Relationship, Drug; Electrocardiography; Female; Halothane; Heart Conduction System; Humans; Isoindoles; Long QT Syndrome; Middle Aged; Models, Animal; Piperazines; Piperidines; Potassium Channel Blockers; Serotonin Antagonists; Sleep Initiation and Maintenance Disorders; Thiazoles; Torsades de Pointes | 2020 |
Antihyperalgesic effects of intrathecal perospirone in a rat model of neuropathic pain.
Topics: Analgesics; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Hyperalgesia; Injections, Spinal; Isoindoles; Male; Neuralgia; Pain Measurement; Piperazines; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT1A; Rotarod Performance Test; Serotonin 5-HT1 Receptor Antagonists; Signal Transduction; Thiazoles | 2020 |
Cost-effectiveness of population-based screening for diabetes and hypertension in India: an economic modelling study.
Topics: Adult; Age Factors; Aged; Comorbidity; Cost-Benefit Analysis; Decision Trees; Diabetes Mellitus; Female; Humans; Hypertension; India; Isoindoles; Male; Markov Chains; Mass Screening; Middle Aged; Models, Economic; Patient Acceptance of Health Care; Quality of Life; Quality-Adjusted Life Years; Thiazoles | 2022 |
Safety and Effectiveness of Perospirone in Comparison to Risperidone for Treatment of Delirium in Patients with Advanced Cancer: A Multicenter Prospective Observational Study in Real-World Psycho-Oncology Settings.
Topics: Aged; Antipsychotic Agents; Delirium; Humans; Isoindoles; Neoplasms; Psycho-Oncology; Risperidone; Thiazoles | 2022 |
Perospirone augmentation of escitalopram in the treatment of an adolescent sophophobia (fear of learning) patient.
Topics: Adolescent; Child; Escitalopram; Fear; Humans; Isoindoles; Male; Thiazoles | 2022 |