perospirone has been researched along with spiperone in 2 studies
| Studies (perospirone) | Trials (perospirone) | Recent Studies (post-2010) (perospirone) | Studies (spiperone) | Trials (spiperone) | Recent Studies (post-2010) (spiperone) |
|---|---|---|---|---|---|
| 111 | 24 | 26 | 2,944 | 13 | 85 |
| Protein | Taxonomy | perospirone (IC50) | spiperone (IC50) |
|---|---|---|---|
| Bile salt export pump | Homo sapiens (human) | 10 | |
| D(2) dopamine receptor | Homo sapiens (human) | 0.0008 | |
| Alpha-1B adrenergic receptor | Rattus norvegicus (Norway rat) | 0.097 | |
| D(4) dopamine receptor | Homo sapiens (human) | 0.0005 | |
| Alpha-1D adrenergic receptor | Rattus norvegicus (Norway rat) | 0.097 | |
| Histamine H1 receptor | Cavia porcellus (domestic guinea pig) | 0.097 | |
| D(3) dopamine receptor | Homo sapiens (human) | 0.0635 | |
| Alpha-1A adrenergic receptor | Rattus norvegicus (Norway rat) | 0.097 | |
| D(2) dopamine receptor | Rattus norvegicus (Norway rat) | 0.0001 | |
| Sigma non-opioid intracellular receptor 1 | Homo sapiens (human) | 0.955 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hirose, A; Kato, T; Katsube, J; Nakamura, M; Ohno, Y; Shimizu, H; Tanaka, H | 1 |
| Iwata, Y; Minabe, Y; Mori, N; Nakamura, K; Okada, H; Ouchi, Y; Sekine, Y; Sugihara, G; Suzuki, K; Takei, N; Tsuchiya, KJ; Yoshikawa, E | 1 |
1 trial(s) available for perospirone and spiperone
| Article | Year |
|---|---|
Perospirone is a new generation antipsychotic: evidence from a positron emission tomography study of serotonin 2 and D2 receptor occupancy in the living human brain.
Topics: Adult; Antipsychotic Agents; Binding, Competitive; Brain; Humans; Indoles; Isoindoles; Male; Positron-Emission Tomography; Raclopride; Radiopharmaceuticals; Receptors, Dopamine D2; Receptors, Serotonin, 5-HT2; Reference Values; Spiperone; Thiazoles | 2006 |
1 other study(ies) available for perospirone and spiperone
| Article | Year |
|---|---|
Pharmacological actions of SM-9018, a new neuroleptic drug with both potent 5-hydroxytryptamine2 and dopamine2 antagonistic actions.
Topics: Animals; Antipsychotic Agents; Behavior, Animal; Brain Chemistry; Catalepsy; Dopamine Antagonists; Indoles; Isoindoles; Ketanserin; Male; Methamphetamine; Mice; Mice, Inbred Strains; Motor Activity; Norepinephrine; Parasympatholytics; Psychomotor Performance; Rats; Rats, Inbred Strains; Serotonin Antagonists; Spiperone; Stereotyped Behavior; Thiazoles | 1990 |