Compounds > perospirone
Page last updated: 2024-09-03

perospirone and sertindole

perospirone has been researched along with sertindole in 1 studies

Compound Research Comparison

Studies
(perospirone)		Trials
(perospirone)		Recent Studies (post-2010)
(perospirone)		Studies
(sertindole)		Trials
(sertindole)		Recent Studies (post-2010) (sertindole)
11124262763467

Protein Interaction Comparison

ProteinTaxonomyperospirone (IC50)sertindole (IC50)
Voltage-dependent L-type calcium channel subunit alpha-1CCavia porcellus (domestic guinea pig)8.9
Voltage-dependent L-type calcium channel subunit alpha-1FHomo sapiens (human)7.6
ATP-dependent translocase ABCB1Homo sapiens (human)6.5
5-hydroxytryptamine receptor 2CRattus norvegicus (Norway rat)0.0004
5-hydroxytryptamine receptor 2ARattus norvegicus (Norway rat)0.0004
Alpha-1B adrenergic receptorRattus norvegicus (Norway rat)0.0034
Potassium voltage-gated channel subfamily A member 5Homo sapiens (human)2
Alpha-1D adrenergic receptorRattus norvegicus (Norway rat)0.0034
5-hydroxytryptamine receptor 2BRattus norvegicus (Norway rat)0.0004
Sodium channel protein type 1 subunit alphaHomo sapiens (human)2.3
Sodium channel protein type 4 subunit alphaHomo sapiens (human)2.3
Alpha-1A adrenergic receptorRattus norvegicus (Norway rat)0.0034
D(2) dopamine receptorRattus norvegicus (Norway rat)0.0041
Sodium channel protein type 7 subunit alphaHomo sapiens (human)2.3
Voltage-dependent L-type calcium channel subunit alpha-1D Homo sapiens (human)7.6
Potassium voltage-gated channel subfamily H member 2Homo sapiens (human)0.0109
Voltage-dependent L-type calcium channel subunit alpha-1SHomo sapiens (human)7.6
Voltage-dependent L-type calcium channel subunit alpha-1CHomo sapiens (human)7.6
Sodium channel protein type 5 subunit alphaHomo sapiens (human)2.3
Sodium channel protein type 9 subunit alphaHomo sapiens (human)2.3
Sodium channel protein type 2 subunit alphaHomo sapiens (human)2.3
Sodium channel protein type 3 subunit alphaHomo sapiens (human)2.3
Sodium channel protein type 11 subunit alphaHomo sapiens (human)2.3
Sodium channel protein type 8 subunit alphaHomo sapiens (human)2.3
Sodium channel protein type 10 subunit alphaHomo sapiens (human)2.3

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Seeman, P; Tallerico, T1

Reviews

1 review(s) available for perospirone and sertindole

ArticleYear
Antipsychotic drugs which elicit little or no parkinsonism bind more loosely than dopamine to brain D2 receptors, yet occupy high levels of these receptors.
    Molecular psychiatry, 1998, Volume: 3, Issue:2

    Topics: Antipsychotic Agents; Binding, Competitive; Cholinergic Antagonists; Clozapine; Corpus Striatum; Dopamine; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Dose-Response Relationship, Drug; Drug Resistance; Dyskinesia, Drug-Induced; Humans; Levodopa; Ligands; Limbic System; Nerve Tissue Proteins; Parkinson Disease, Secondary; Protein Binding; Psychoses, Substance-Induced; Psychotic Disorders; Radioligand Assay; Receptors, Dopamine D2; Receptors, Muscarinic; Receptors, Serotonin; Recurrence; Serotonin Antagonists; Tomography, Emission-Computed

1998