perospirone has been researched along with risperidone in 17 studies
| Studies (perospirone) | Trials (perospirone) | Recent Studies (post-2010) (perospirone) | Studies (risperidone) | Trials (risperidone) | Recent Studies (post-2010) (risperidone) |
|---|---|---|---|---|---|
| 111 | 24 | 26 | 6,924 | 1,505 | 2,477 |
| Protein | Taxonomy | perospirone (IC50) | risperidone (IC50) |
|---|---|---|---|
| 5-hydroxytryptamine receptor 4 | Cavia porcellus (domestic guinea pig) | 0.015 | |
| 5-hydroxytryptamine receptor 2C | Rattus norvegicus (Norway rat) | 0.0027 | |
| Alpha-2A adrenergic receptor | Homo sapiens (human) | 0.0097 | |
| Cytochrome P450 2D6 | Homo sapiens (human) | 5.2734 | |
| Angiotensin-converting enzyme | Oryctolagus cuniculus (rabbit) | 4.1901 | |
| D(2) dopamine receptor | Homo sapiens (human) | 0.0167 | |
| 5-hydroxytryptamine receptor 2A | Rattus norvegicus (Norway rat) | 0.0991 | |
| Alpha-2B adrenergic receptor | Homo sapiens (human) | 0.026 | |
| Alpha-2C adrenergic receptor | Homo sapiens (human) | 0.0096 | |
| 5-hydroxytryptamine receptor 1A | Rattus norvegicus (Norway rat) | 0.799 | |
| D(1A) dopamine receptor | Homo sapiens (human) | 0.479 | |
| Histamine H2 receptor | Homo sapiens (human) | 1.483 | |
| Alpha-1D adrenergic receptor | Homo sapiens (human) | 0.01 | |
| 5-hydroxytryptamine receptor 2A | Homo sapiens (human) | 0.0016 | |
| 5-hydroxytryptamine receptor 2C | Homo sapiens (human) | 0.0057 | |
| 5-hydroxytryptamine receptor 1B | Rattus norvegicus (Norway rat) | 0.799 | |
| 5-hydroxytryptamine receptor 2B | Rattus norvegicus (Norway rat) | 0.0027 | |
| 5-hydroxytryptamine receptor 2C | Mus musculus (house mouse) | 0.0015 | |
| Alpha-1A adrenergic receptor | Homo sapiens (human) | 0.0105 | |
| 5-hydroxytryptamine receptor 2A | Mus musculus (house mouse) | 0.0015 | |
| Histamine H1 receptor | Homo sapiens (human) | 0.4515 | |
| D(3) dopamine receptor | Homo sapiens (human) | 0.024 | |
| 5-hydroxytryptamine receptor 2B | Homo sapiens (human) | 0.023 | |
| D(2) dopamine receptor | Mus musculus (house mouse) | 0.023 | |
| D(2) dopamine receptor | Rattus norvegicus (Norway rat) | 0.0154 | |
| 5-hydroxytryptamine receptor 2B | Mus musculus (house mouse) | 0.0015 | |
| Potassium voltage-gated channel subfamily H member 2 | Homo sapiens (human) | 0.6303 | |
| 5-hydroxytryptamine receptor 1A | Mus musculus (house mouse) | 0.43 | |
| Nuclear receptor subfamily 3 group C member 3 | Bos taurus (cattle) | 4.1901 | |
| Multidrug and toxin extrusion protein 1 | Homo sapiens (human) | 1.6 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (5.88) | 18.2507 |
| 2000's | 13 (76.47) | 29.6817 |
| 2010's | 2 (11.76) | 24.3611 |
| 2020's | 1 (5.88) | 2.80 |
| Authors | Studies |
|---|---|
| Ishibashi, T; Ishida-Tokuda, K; Morita, T; Nakamura, M; Ohno, Y; Sakamoto, H; Tojima, R; Wakabayashi, J | 1 |
| Kameda, K; Koyama, T; Kusumi, I; Suzuki, K; Takahashi, Y | 1 |
| Iseki, E; Kase, A; Katsuse, O; Kosaka, K; Oyama, I; Shoji, M; Togo, T; Uchikado, H | 1 |
| Nishikawa, T; Takeuchi, T | 1 |
| Koyama, T; Nakagawa, S | 1 |
| Ito, C; Ojima, T; Sakurai, E; Watanabe, T; Yanai, K | 1 |
| Mori, K; Morinobu, S; Nagao, M; Okamoto, Y; Yamashita, H; Yamawaki, S | 2 |
| Abekawa, T; Kitaichi, Y; Koyama, T; Matsuyama, T | 1 |
| Egashira, N; Fujiwara, M; Harada, S; Iwasaki, K; Matsushita, M; Mishima, K; Nishimura, R; Okuno, R | 1 |
| Asai, K; Shimada, Y; Tanaka, Y; Ueda, H; Yoshida, S | 1 |
| Hamanaka, S; Kamijo, Y | 1 |
| Dierks, T; Irisawa, S; Isotani, T; Kikuchi, M; Kinoshita, T; Koenig, T; Okugawa, G; Strik, W; Yagyu, T; Yamada, K; Yoshimura, M | 1 |
| Kato, M; Kinoshita, T; Kishimoto, T; Koh, J; Matsumoto, N; Morikawa, M; Okugawa, G; Shinosaki, K; Wakeno, M; Yoneda, H | 1 |
| Fujii, A; Furukori, H; Inoue, Y; Kaneko, S; Sugawara, N; Tsuchimine, S; Yasui-Furukori, N | 1 |
| Fujiki, R; Matsuoka, T; Mori, K; Morita, K; Shoji, Y; Uchimura, N | 1 |
| Inoue, S; Maeda, I; Ogawa, A; Terada, S; Yamada, N; Yoshiuchi, K | 1 |
2 review(s) available for perospirone and risperidone
| Article | Year |
|---|---|
[An introduction to antipsychotics].
Topics: Antipsychotic Agents; Benzodiazepines; Dibenzothiazepines; Dopamine Antagonists; Humans; Indoles; Isoindoles; Olanzapine; Pirenzepine; Quetiapine Fumarate; Receptors, Dopamine; Receptors, Serotonin; Risperidone; Schizophrenia; Serotonin Antagonists; Thiazoles | 2003 |
[Extrapyramidal syndrome].
Topics: Acute Disease; Akathisia, Drug-Induced; Antipsychotic Agents; Basal Ganglia Diseases; Dibenzothiazepines; Dopamine D2 Receptor Antagonists; Dystonia; Humans; Indoles; Isoindoles; Parkinsonian Disorders; Quetiapine Fumarate; Receptors, Muscarinic; Receptors, Serotonin; Risperidone; Serotonin Antagonists; Syndrome; Thiazoles | 2003 |
5 trial(s) available for perospirone and risperidone
| Article | Year |
|---|---|
Prolactin levels in schizophrenic patients receiving perospirone in comparison to risperidone.
Topics: Antipsychotic Agents; Dose-Response Relationship, Drug; Female; Humans; Indoles; Isoindoles; Male; Middle Aged; Prolactin; Risperidone; Schizophrenia; Thiazoles | 2003 |
Effects of changing from typical to atypical antipsychotic drugs on subjective sleep quality in patients with schizophrenia in a Japanese population.
Topics: Adult; Aged; Antipsychotic Agents; Benzodiazepines; Dibenzothiazepines; Drug Administration Schedule; Female; Health Status; Hospitalization; Humans; Indoles; Isoindoles; Japan; Male; Middle Aged; Olanzapine; Psychiatric Status Rating Scales; Quetiapine Fumarate; Regression Analysis; Risperidone; Schizophrenia; Schizophrenic Psychology; Severity of Illness Index; Sleep; Thiazoles | 2004 |
Influence of aging on the improvement of subjective sleep quality by atypical antipsychotic drugs in patients with schizophrenia: comparison of middle-aged and older adults.
Topics: Adult; Age Factors; Aged; Aged, 80 and over; Antipsychotic Agents; Benzodiazepines; Dibenzothiazepines; Female; Humans; Indoles; Isoindoles; Male; Middle Aged; Olanzapine; Polysomnography; Psychiatric Status Rating Scales; Quetiapine Fumarate; Risperidone; Schizophrenia; Schizophrenic Psychology; Sleep Initiation and Maintenance Disorders; Sleep Stages; Thiazoles | 2005 |
A pharmaco-EEG study on antipsychotic drugs in healthy volunteers.
Topics: Adult; Antipsychotic Agents; Benzodiazepines; Chlorpromazine; Cross-Over Studies; Dibenzothiazepines; Electroencephalography; Fourier Analysis; Haloperidol; Humans; Indoles; Isoindoles; Male; Olanzapine; Quetiapine Fumarate; Reference Values; Risperidone; Single-Blind Method; Thiazoles; Time Factors | 2007 |
Randomized clinical comparison of perospirone and risperidone in patients with schizophrenia: Kansai Psychiatric Multicenter Study.
Topics: Adolescent; Adult; Aged; Antipsychotic Agents; Basal Ganglia Diseases; Female; Humans; Isoindoles; Male; Middle Aged; Psychiatric Status Rating Scales; Risperidone; Schizophrenia; Schizophrenic Psychology; Thiazoles | 2009 |
10 other study(ies) available for perospirone and risperidone
| Article | Year |
|---|---|
Evaluation of perospirone (SM-9018), a novel serotonin-2 and dopamine-2 receptor antagonist, and other antipsychotics in the conditioned fear stress-induced freezing behavior model in rats.
Topics: Animals; Antipsychotic Agents; Clozapine; Dopamine Antagonists; Fear; Indoles; Isoindoles; Male; Rats; Rats, Sprague-Dawley; Risperidone; Serotonin Antagonists; Thiazoles | 1996 |
Differential effects of subchronic treatments with atypical antipsychotic drugs on dopamine D2 and serotonin 5-HT2A receptors in the rat brain.
Topics: Animals; Antipsychotic Agents; Benzodiazepines; Brain Chemistry; Chlorpromazine; Dopamine Antagonists; Dose-Response Relationship, Drug; Humans; Indoles; Isoindoles; Male; Olanzapine; Pirenzepine; Protein Binding; Quinolines; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT2A; Receptors, Dopamine D2; Receptors, Serotonin; Risperidone; Selective Serotonin Reuptake Inhibitors; Thiazoles | 2000 |
Effects of serotonin-dopamine antagonists on prepulse inhibition and neurotransmitter contents in the rat cortex.
Topics: Animals; Antipsychotic Agents; Cerebral Cortex; Cognition; Dopamine; Dopamine Antagonists; Haloperidol; Indoles; Isoindoles; Male; Neurotransmitter Agents; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Reflex, Startle; Risperidone; Serotonin; Serotonin Antagonists; Thiazoles | 2004 |
[Treatment of "the premonitory state of schizophrenia" with atypical antipsychotics].
Topics: Adult; Antipsychotic Agents; Benzodiazepines; Female; Humans; Indoles; Isoindoles; Male; Middle Aged; Olanzapine; Risperidone; Schizophrenia; Thiazoles | 2004 |
Perospirone, a novel antipsychotic drug, inhibits marble-burying behavior via 5-HT1A receptor in mice: implications for obsessive-compulsive disorder.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Antipsychotic Agents; Behavior, Animal; Disease Models, Animal; Dose-Response Relationship, Drug; Haloperidol; Indoles; Isoindoles; Male; Mice; Mice, Inbred ICR; Motor Activity; Obsessive-Compulsive Disorder; Piperazines; Receptor, Serotonin, 5-HT1A; Risperidone; Serotonin Antagonists; Serotonin Receptor Agonists; Thiazoles | 2005 |
Alteration in serum neural cell adhesion molecule in patients of schizophrenia.
Topics: Adult; Age Factors; Antipsychotic Agents; Benzodiazepines; Blotting, Western; Chronic Disease; Dibenzothiazepines; Female; Humans; Indoles; Isoindoles; Male; Middle Aged; Molecular Weight; Neural Cell Adhesion Molecules; Olanzapine; Protein Isoforms; Quetiapine Fumarate; Risperidone; Schizophrenia; Thiazoles | 2007 |
New-onset diabetic ketoacidosis induced by the addition of perospirone hydrochloride in a patient treated with risperidone.
Topics: Adult; Diabetic Ketoacidosis; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Follow-Up Studies; Humans; Indoles; Isoindoles; Male; Risk Assessment; Risperidone; Schizophrenia; Severity of Illness Index; Thiazoles; Treatment Outcome | 2007 |
Prolactin fluctuation over the course of a day during treatments with three atypical antipsychotics in schizophrenic patients.
Topics: Adult; Antipsychotic Agents; Benzodiazepines; Circadian Rhythm; Drug Administration Schedule; Drug Monitoring; Female; Humans; Hyperprolactinemia; Isoindoles; Male; Middle Aged; Olanzapine; Prolactin; Risperidone; Schizophrenia; Thiazoles; Time Factors; Treatment Outcome | 2010 |
State and trait markers of emotionally charged visual event-related potentials (P300) in drug-naïve schizophrenia.
Topics: Adolescent; Adult; Antipsychotic Agents; Benzodiazepines; Case-Control Studies; Emotions; Event-Related Potentials, P300; Evoked Potentials, Visual; Facial Expression; Female; Humans; Isoindoles; Male; Olanzapine; Photic Stimulation; Psychomotor Performance; Reaction Time; Risperidone; Schizophrenia; Schizophrenic Psychology; Thiazoles | 2012 |
Safety and Effectiveness of Perospirone in Comparison to Risperidone for Treatment of Delirium in Patients with Advanced Cancer: A Multicenter Prospective Observational Study in Real-World Psycho-Oncology Settings.
Topics: Aged; Antipsychotic Agents; Delirium; Humans; Isoindoles; Neoplasms; Psycho-Oncology; Risperidone; Thiazoles | 2022 |