perospirone has been researched along with raclopride in 4 studies
| Studies (perospirone) | Trials (perospirone) | Recent Studies (post-2010) (perospirone) | Studies (raclopride) | Trials (raclopride) | Recent Studies (post-2010) (raclopride) |
|---|---|---|---|---|---|
| 111 | 24 | 26 | 1,802 | 132 | 419 |
| Protein | Taxonomy | perospirone (IC50) | raclopride (IC50) |
|---|---|---|---|
| D(2) dopamine receptor | Homo sapiens (human) | 0.052 | |
| D(2) dopamine receptor | Mus musculus (house mouse) | 0.032 | |
| D(2) dopamine receptor | Rattus norvegicus (Norway rat) | 0.0279 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 2 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ishibashi, T; Ishida, K; Nakamura, M; Ohno, Y; Okada, K | 1 |
| Iwata, Y; Minabe, Y; Mori, N; Nakamura, K; Okada, H; Ouchi, Y; Sekine, Y; Sugihara, G; Suzuki, K; Takei, N; Tsuchiya, KJ; Yoshikawa, E | 1 |
| Arakawa, R; Ito, H; Okubo, Y; Okumura, M; Suhara, T; Takahashi, H; Takano, A; Takano, H | 1 |
| Arakawa, R; Kanamitsu, K; Kusuhara, H; Sugiyama, Y; Suhara, T | 1 |
1 trial(s) available for perospirone and raclopride
| Article | Year |
|---|---|
Perospirone is a new generation antipsychotic: evidence from a positron emission tomography study of serotonin 2 and D2 receptor occupancy in the living human brain.
Topics: Adult; Antipsychotic Agents; Binding, Competitive; Brain; Humans; Indoles; Isoindoles; Male; Positron-Emission Tomography; Raclopride; Radiopharmaceuticals; Receptors, Dopamine D2; Receptors, Serotonin, 5-HT2; Reference Values; Spiperone; Thiazoles | 2006 |
3 other study(ies) available for perospirone and raclopride
| Article | Year |
|---|---|
Effects of subchronic treatments with SM-9018, a novel 5-HT2 and D2 antagonist, on dopamine and 5-HT receptors in rats.
Topics: Animals; Antipsychotic Agents; Binding, Competitive; Haloperidol; Indoles; Isoindoles; Male; Raclopride; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D2; Receptors, Serotonin; Salicylamides; Serotonin Antagonists; Thiazoles; Up-Regulation | 1995 |
Dopamine D2 receptor occupancy by perospirone: a positron emission tomography study in patients with schizophrenia and healthy subjects.
Topics: Adult; Antipsychotic Agents; Binding, Competitive; Brain; Case-Control Studies; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Female; Humans; Isoindoles; Magnetic Resonance Imaging; Male; Positron-Emission Tomography; Raclopride; Receptors, Dopamine D2; Schizophrenia; Thiazoles; Time Factors | 2010 |
Prediction of CNS occupancy of dopamine D2 receptor based on systemic exposure and in vitro experiments.
Topics: Adult; Animals; Antipsychotic Agents; Brain; Computer Simulation; Dopamine D2 Receptor Antagonists; Humans; Isoindoles; Kinetics; Male; Mice, Inbred ICR; Positron-Emission Tomography; Quetiapine Fumarate; Raclopride; Receptors, Dopamine D2; Thiazoles; Young Adult | 2016 |