Page last updated: 2024-09-03

perospirone and olanzapine

perospirone has been researched along with olanzapine in 10 studies

Compound Research Comparison

Studies
(perospirone)
Trials
(perospirone)
Recent Studies (post-2010)
(perospirone)
Studies
(olanzapine)
Trials
(olanzapine)
Recent Studies (post-2010) (olanzapine)
11124266,3391,3402,383

Protein Interaction Comparison

ProteinTaxonomyperospirone (IC50)olanzapine (IC50)
5-hydroxytryptamine receptor 4Cavia porcellus (domestic guinea pig)0.097
Muscarinic acetylcholine receptor M4Homo sapiens (human)0.155
5-hydroxytryptamine receptor 2CRattus norvegicus (Norway rat)0.047
Muscarinic acetylcholine receptor M5Homo sapiens (human)0.04
Alpha-2A adrenergic receptorHomo sapiens (human)0.541
Polyunsaturated fatty acid lipoxygenase ALOX15Oryctolagus cuniculus (rabbit)2.768
D(2) dopamine receptorHomo sapiens (human)0.118
5-hydroxytryptamine receptor 2ARattus norvegicus (Norway rat)0.047
Alpha-2B adrenergic receptorHomo sapiens (human)0.421
Alpha-2C adrenergic receptorHomo sapiens (human)0.531
Muscarinic acetylcholine receptor M3Homo sapiens (human)0.392
D(1A) dopamine receptorHomo sapiens (human)0.072
D(4) dopamine receptorHomo sapiens (human)0.173
Alpha-1D adrenergic receptorHomo sapiens (human)0.092
5-hydroxytryptamine receptor 2AHomo sapiens (human)0.038
5-hydroxytryptamine receptor 2CHomo sapiens (human)0.021
5-hydroxytryptamine receptor 2BRattus norvegicus (Norway rat)0.047
Sodium-dependent serotonin transporterHomo sapiens (human)1.033
Histamine H1 receptorHomo sapiens (human)0.013
D(3) dopamine receptorHomo sapiens (human)0.078
5-hydroxytryptamine receptor 2BHomo sapiens (human)0.057
5-hydroxytryptamine receptor 6Homo sapiens (human)0.013
D(2) dopamine receptorRattus norvegicus (Norway rat)0.158
Potassium voltage-gated channel subfamily H member 2Homo sapiens (human)0.2028

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's7 (70.00)29.6817
2010's3 (30.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kameda, K; Koyama, T; Kusumi, I; Suzuki, K; Takahashi, Y1
Nishikawa, T; Takeuchi, T1
Mori, K; Morinobu, S; Nagao, M; Okamoto, Y; Yamashita, H; Yamawaki, S2
Abekawa, T; Kitaichi, Y; Koyama, T; Matsuyama, T1
Asai, K; Shimada, Y; Tanaka, Y; Ueda, H; Yoshida, S1
Dierks, T; Irisawa, S; Isotani, T; Kikuchi, M; Kinoshita, T; Koenig, T; Okugawa, G; Strik, W; Yagyu, T; Yamada, K; Yoshimura, M1
Fujii, A; Furukori, H; Inoue, Y; Kaneko, S; Sugawara, N; Tsuchimine, S; Yasui-Furukori, N1
Gen, K; Inoue, Y; Suzuki, H1
Fujiki, R; Matsuoka, T; Mori, K; Morita, K; Shoji, Y; Uchimura, N1

Reviews

1 review(s) available for perospirone and olanzapine

ArticleYear
[An introduction to antipsychotics].
    Ryoikibetsu shokogun shirizu, 2003, Issue:38

    Topics: Antipsychotic Agents; Benzodiazepines; Dibenzothiazepines; Dopamine Antagonists; Humans; Indoles; Isoindoles; Olanzapine; Pirenzepine; Quetiapine Fumarate; Receptors, Dopamine; Receptors, Serotonin; Risperidone; Schizophrenia; Serotonin Antagonists; Thiazoles

2003

Trials

4 trial(s) available for perospirone and olanzapine

ArticleYear
Effects of changing from typical to atypical antipsychotic drugs on subjective sleep quality in patients with schizophrenia in a Japanese population.
    The Journal of clinical psychiatry, 2004, Volume: 65, Issue:11

    Topics: Adult; Aged; Antipsychotic Agents; Benzodiazepines; Dibenzothiazepines; Drug Administration Schedule; Female; Health Status; Hospitalization; Humans; Indoles; Isoindoles; Japan; Male; Middle Aged; Olanzapine; Psychiatric Status Rating Scales; Quetiapine Fumarate; Regression Analysis; Risperidone; Schizophrenia; Schizophrenic Psychology; Severity of Illness Index; Sleep; Thiazoles

2004
Influence of aging on the improvement of subjective sleep quality by atypical antipsychotic drugs in patients with schizophrenia: comparison of middle-aged and older adults.
    The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry, 2005, Volume: 13, Issue:5

    Topics: Adult; Age Factors; Aged; Aged, 80 and over; Antipsychotic Agents; Benzodiazepines; Dibenzothiazepines; Female; Humans; Indoles; Isoindoles; Male; Middle Aged; Olanzapine; Polysomnography; Psychiatric Status Rating Scales; Quetiapine Fumarate; Risperidone; Schizophrenia; Schizophrenic Psychology; Sleep Initiation and Maintenance Disorders; Sleep Stages; Thiazoles

2005
A pharmaco-EEG study on antipsychotic drugs in healthy volunteers.
    Psychopharmacology, 2007, Volume: 191, Issue:4

    Topics: Adult; Antipsychotic Agents; Benzodiazepines; Chlorpromazine; Cross-Over Studies; Dibenzothiazepines; Electroencephalography; Fourier Analysis; Haloperidol; Humans; Indoles; Isoindoles; Male; Olanzapine; Quetiapine Fumarate; Reference Values; Risperidone; Single-Blind Method; Thiazoles; Time Factors

2007
An unblinded comparison of the clinical and cognitive effects of switching from first-generation antipsychotics to aripiprazole, perospirone or olanzapine in patients with chronic schizophrenia.
    Progress in neuro-psychopharmacology & biological psychiatry, 2011, Jan-15, Volume: 35, Issue:1

    Topics: Adult; Aged; Antipsychotic Agents; Aripiprazole; Attention; Benzodiazepines; Chronic Disease; Cognition Disorders; Dose-Response Relationship, Drug; Drug Substitution; Executive Function; Female; Humans; Isoindoles; Longitudinal Studies; Male; Memory; Middle Aged; Neuropsychological Tests; Olanzapine; Piperazines; Psychiatric Status Rating Scales; Quinolones; Schizophrenia; Single-Blind Method; Thiazoles; Time Factors; Verbal Learning

2011

Other Studies

5 other study(ies) available for perospirone and olanzapine

ArticleYear
Differential effects of subchronic treatments with atypical antipsychotic drugs on dopamine D2 and serotonin 5-HT2A receptors in the rat brain.
    Journal of neural transmission (Vienna, Austria : 1996), 2000, Volume: 107, Issue:3

    Topics: Animals; Antipsychotic Agents; Benzodiazepines; Brain Chemistry; Chlorpromazine; Dopamine Antagonists; Dose-Response Relationship, Drug; Humans; Indoles; Isoindoles; Male; Olanzapine; Pirenzepine; Protein Binding; Quinolines; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT2A; Receptors, Dopamine D2; Receptors, Serotonin; Risperidone; Selective Serotonin Reuptake Inhibitors; Thiazoles

2000
[Treatment of "the premonitory state of schizophrenia" with atypical antipsychotics].
    Seishin shinkeigaku zasshi = Psychiatria et neurologia Japonica, 2004, Volume: 106, Issue:11

    Topics: Adult; Antipsychotic Agents; Benzodiazepines; Female; Humans; Indoles; Isoindoles; Male; Middle Aged; Olanzapine; Risperidone; Schizophrenia; Thiazoles

2004
Alteration in serum neural cell adhesion molecule in patients of schizophrenia.
    Human psychopharmacology, 2007, Volume: 22, Issue:2

    Topics: Adult; Age Factors; Antipsychotic Agents; Benzodiazepines; Blotting, Western; Chronic Disease; Dibenzothiazepines; Female; Humans; Indoles; Isoindoles; Male; Middle Aged; Molecular Weight; Neural Cell Adhesion Molecules; Olanzapine; Protein Isoforms; Quetiapine Fumarate; Risperidone; Schizophrenia; Thiazoles

2007
Prolactin fluctuation over the course of a day during treatments with three atypical antipsychotics in schizophrenic patients.
    Human psychopharmacology, 2010, Volume: 25, Issue:3

    Topics: Adult; Antipsychotic Agents; Benzodiazepines; Circadian Rhythm; Drug Administration Schedule; Drug Monitoring; Female; Humans; Hyperprolactinemia; Isoindoles; Male; Middle Aged; Olanzapine; Prolactin; Risperidone; Schizophrenia; Thiazoles; Time Factors; Treatment Outcome

2010
State and trait markers of emotionally charged visual event-related potentials (P300) in drug-naïve schizophrenia.
    Psychiatry and clinical neurosciences, 2012, Volume: 66, Issue:4

    Topics: Adolescent; Adult; Antipsychotic Agents; Benzodiazepines; Case-Control Studies; Emotions; Event-Related Potentials, P300; Evoked Potentials, Visual; Facial Expression; Female; Humans; Isoindoles; Male; Olanzapine; Photic Stimulation; Psychomotor Performance; Reaction Time; Risperidone; Schizophrenia; Schizophrenic Psychology; Thiazoles

2012