Page last updated: 2024-09-03

perospirone and aripiprazole

perospirone has been researched along with aripiprazole in 8 studies

Compound Research Comparison

Studies
(perospirone)
Trials
(perospirone)
Recent Studies (post-2010)
(perospirone)
Studies
(aripiprazole)
Trials
(aripiprazole)
Recent Studies (post-2010) (aripiprazole)
11124262,9895091,788

Protein Interaction Comparison

ProteinTaxonomyperospirone (IC50)aripiprazole (IC50)
ATP-dependent translocase ABCB1Homo sapiens (human)0.78
D(2) dopamine receptorHomo sapiens (human)0.0158
5-hydroxytryptamine receptor 2AHomo sapiens (human)1.945
5-hydroxytryptamine receptor 2CHomo sapiens (human)1.38
Alpha-1A adrenergic receptorHomo sapiens (human)0.17
Histamine H1 receptorHomo sapiens (human)0.42
Potassium voltage-gated channel subfamily H member 2Homo sapiens (human)1.8572

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (12.50)29.6817
2010's7 (87.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Li, HD; Li, KY; Ren, HY; Wang, F; Zhang, BK; Zhou, YG1
Hori, H; Nakamura, J; Okamoto, T; Umene-Nakano, W; Yoshimura, R1
Gen, K; Inoue, Y; Suzuki, H1
Caccia, S1
Kato, M; Kinoshita, T; Nishida, K; Okugawa, G; Sakai, S; Suwa, A; Takekita, Y; Wakeno, M1
Fabbri, C; Kato, M; Kinoshita, T; Koshikawa, Y; Nonen, S; Okugawa, G; Sakai, S; Serretti, A; Sunada, N; Takekita, Y; Wakeno, M3

Reviews

1 review(s) available for perospirone and aripiprazole

ArticleYear
Pharmacokinetics and metabolism update for some recent antipsychotics.
    Expert opinion on drug metabolism & toxicology, 2011, Volume: 7, Issue:7

    Topics: Animals; Antipsychotic Agents; Aripiprazole; Drug Interactions; Humans; Inactivation, Metabolic; Isoindoles; Lurasidone Hydrochloride; Piperazines; Quinolones; Thiazoles

2011

Trials

5 trial(s) available for perospirone and aripiprazole

ArticleYear
An unblinded comparison of the clinical and cognitive effects of switching from first-generation antipsychotics to aripiprazole, perospirone or olanzapine in patients with chronic schizophrenia.
    Progress in neuro-psychopharmacology & biological psychiatry, 2011, Jan-15, Volume: 35, Issue:1

    Topics: Adult; Aged; Antipsychotic Agents; Aripiprazole; Attention; Benzodiazepines; Chronic Disease; Cognition Disorders; Dose-Response Relationship, Drug; Drug Substitution; Executive Function; Female; Humans; Isoindoles; Longitudinal Studies; Male; Memory; Middle Aged; Neuropsychological Tests; Olanzapine; Piperazines; Psychiatric Status Rating Scales; Quinolones; Schizophrenia; Single-Blind Method; Thiazoles; Time Factors; Verbal Learning

2011
A 12-week randomized, open-label study of perospirone versus aripiprazole in the treatment of Japanese schizophrenia patients.
    Progress in neuro-psychopharmacology & biological psychiatry, 2013, Jan-10, Volume: 40

    Topics: Adolescent; Adult; Aged; Antipsychotic Agents; Aripiprazole; Female; Humans; Isoindoles; Japan; Male; Middle Aged; Piperazines; Quinolones; Schizophrenia; Severity of Illness Index; Thiazoles; Treatment Outcome

2013
HTR1A Gene Polymorphisms and 5-HT1A Receptor Partial Agonist Antipsychotics Efficacy in Schizophrenia.
    Journal of clinical psychopharmacology, 2015, Volume: 35, Issue:3

    Topics: Adult; Antipsychotic Agents; Aripiprazole; Female; Haplotypes; Humans; Isoindoles; Male; Middle Aged; Polymorphism, Single Nucleotide; Receptor, Serotonin, 5-HT1A; Schizophrenia; Serotonin 5-HT1 Receptor Agonists; Thiazoles; Treatment Outcome

2015
Antagonist and partial agonist at the dopamine D2 receptors in drug-naïve and non-drug-naïve schizophrenia: a randomized, controlled trial.
    European archives of psychiatry and clinical neuroscience, 2015, Volume: 265, Issue:7

    Topics: Adult; Aged; Akathisia, Drug-Induced; Antipsychotic Agents; Aripiprazole; Basal Ganglia Diseases; Dopamine Agonists; Dopamine D2 Receptor Antagonists; Drug Partial Agonism; Female; Humans; Isoindoles; Male; Middle Aged; Receptors, Dopamine D2; Schizophrenia; Schizophrenic Psychology; Thiazoles; Treatment Outcome; Young Adult

2015
Serotonin 7 Receptor Variants Are Not Associated with Response to Second-Generation Antipsychotics in Japanese Schizophrenia Patients.
    Neuropsychobiology, 2015, Volume: 72, Issue:2

    Topics: Adult; Antipsychotic Agents; Aripiprazole; Asian People; Female; Humans; Isoindoles; Japan; Linkage Disequilibrium; Male; Middle Aged; Polymorphism, Single Nucleotide; Precision Medicine; Psychiatric Status Rating Scales; Receptors, Serotonin; Schizophrenia; Thiazoles; Treatment Outcome

2015

Other Studies

2 other study(ies) available for perospirone and aripiprazole

ArticleYear
Ultra-performance liquid chromatography-tandem mass spectrometry for the determination of atypical antipsychotics and some metabolites in in vitro samples.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2007, May-01, Volume: 850, Issue:1-2

    Topics: Antipsychotic Agents; Aripiprazole; Chromatography, High Pressure Liquid; Dibenzothiazepines; Indoles; Isoindoles; Piperazines; Quetiapine Fumarate; Quinolones; Reference Standards; Reproducibility of Results; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry; Thiazoles

2007
A case of schizophrenia with Meige syndrome induced by long-term aripiprazole successfully treated with perospirone.
    Progress in neuro-psychopharmacology & biological psychiatry, 2011, Jan-15, Volume: 35, Issue:1

    Topics: Antipsychotic Agents; Aripiprazole; Female; Humans; Isoindoles; Meige Syndrome; Piperazines; Quinolones; Schizophrenia; Thiazoles; Young Adult

2011