perospirone has been researched along with 8-hydroxy-2-(di-n-propylamino)tetralin in 3 studies
| Studies (perospirone) | Trials (perospirone) | Recent Studies (post-2010) (perospirone) | Studies (8-hydroxy-2-(di-n-propylamino)tetralin) | Trials (8-hydroxy-2-(di-n-propylamino)tetralin) | Recent Studies (post-2010) (8-hydroxy-2-(di-n-propylamino)tetralin) |
|---|---|---|---|---|---|
| 111 | 24 | 26 | 3,530 | 7 | 389 |
| Protein | Taxonomy | perospirone (IC50) | 8-hydroxy-2-(di-n-propylamino)tetralin (IC50) |
|---|---|---|---|
| 5-hydroxytryptamine receptor 1A | Homo sapiens (human) | 0.0012 | |
| 5-hydroxytryptamine receptor 1A | Rattus norvegicus (Norway rat) | 0.0032 | |
| Alpha-2B adrenergic receptor | Rattus norvegicus (Norway rat) | 0.81 | |
| D(2) dopamine receptor | Bos taurus (cattle) | 0.8 | |
| Alpha-2C adrenergic receptor | Rattus norvegicus (Norway rat) | 0.81 | |
| Alpha-2A adrenergic receptor | Rattus norvegicus (Norway rat) | 0.81 | |
| D(2) dopamine receptor | Rattus norvegicus (Norway rat) | 2.8959 | |
| Lysosomal alpha-glucosidase | Bos taurus (cattle) | 0.0021 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 2 (66.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ikeda, K; Ishibashi, T; Ishida, K; Kato, T; Nakamura, M; Ohno, Y | 1 |
| Egashira, N; Fujiwara, M; Harada, S; Iwasaki, K; Matsushita, M; Mishima, K; Nishimura, R; Okuno, R | 1 |
| Fujita, Y; Hagiwara, H; Hashimoto, K; Ishima, T; Iyo, M; Kunitachi, S; Shirayama, Y | 1 |
3 other study(ies) available for perospirone and 8-hydroxy-2-(di-n-propylamino)tetralin
| Article | Year |
|---|---|
Effects of chronic treatments with SM-9018, a potential atypical neuroleptic, on behavioral dopaminergic and serotonergic sensitivities in rats.
Topics: 5-Hydroxytryptophan; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Antipsychotic Agents; Apomorphine; Behavior, Animal; Dopamine; Haloperidol; Indoles; Isoindoles; Male; Motor Activity; Posture; Rats; Rats, Sprague-Dawley; Serotonin; Stereotyped Behavior; Thiazoles | 1995 |
Perospirone, a novel antipsychotic drug, inhibits marble-burying behavior via 5-HT1A receptor in mice: implications for obsessive-compulsive disorder.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Antipsychotic Agents; Behavior, Animal; Disease Models, Animal; Dose-Response Relationship, Drug; Haloperidol; Indoles; Isoindoles; Male; Mice; Mice, Inbred ICR; Motor Activity; Obsessive-Compulsive Disorder; Piperazines; Receptor, Serotonin, 5-HT1A; Risperidone; Serotonin Antagonists; Serotonin Receptor Agonists; Thiazoles | 2005 |
Phencyclidine-induced cognitive deficits in mice are improved by subsequent subchronic administration of the antipsychotic drug perospirone: role of serotonin 5-HT1A receptors.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Analysis of Variance; Animals; Antipsychotic Agents; Behavior, Animal; Body Temperature; Cognition Disorders; Dose-Response Relationship, Drug; Drug Interactions; Injections, Subcutaneous; Isoindoles; Male; Mice; Mice, Inbred ICR; Pattern Recognition, Visual; Phencyclidine; Piperazines; Protein Binding; Pyridines; Receptor, Serotonin, 5-HT1A; Serotonin Antagonists; Serotonin Receptor Agonists; Thiazoles; Time Factors | 2008 |