Compounds > perlolyrine
Page last updated: 2024-09-04

perlolyrine and vardenafil

perlolyrine has been researched along with vardenafil in 1 studies

Compound Research Comparison

Studies
(perlolyrine)		Trials
(perlolyrine)		Recent Studies (post-2010)
(perlolyrine)		Studies
(vardenafil)		Trials
(vardenafil)		Recent Studies (post-2010) (vardenafil)
150732020

Protein Interaction Comparison

ProteinTaxonomyperlolyrine (IC50)vardenafil (IC50)
cystic fibrosis transmembrane conductance regulatorHomo sapiens (human)0.14
cGMP-dependent 3',5'-cyclic phosphodiesteraseHomo sapiens (human)1.7801
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit deltaHomo sapiens (human)0.0077
High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8AHomo sapiens (human)1.6334
cGMP-specific 3',5'-cyclic phosphodiesteraseHomo sapiens (human)0.817
High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9AHomo sapiens (human)0.57
Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alphaHomo sapiens (human)0.0077
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gammaHomo sapiens (human)0.0077
cAMP-specific 3',5'-cyclic phosphodiesterase 4AHomo sapiens (human)4.15
Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit betaHomo sapiens (human)0.0077
Cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha'Homo sapiens (human)0.0077
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1AHomo sapiens (human)0.265
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1BHomo sapiens (human)1.3846
cAMP-specific 3',5'-cyclic phosphodiesterase 4BHomo sapiens (human)2.091
cAMP-specific 3',5'-cyclic phosphodiesterase 4CHomo sapiens (human)4.15
cAMP-specific 3',5'-cyclic phosphodiesterase 4DHomo sapiens (human)2.091
cGMP-inhibited 3',5'-cyclic phosphodiesterase BHomo sapiens (human)1.5801
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7AHomo sapiens (human)1.9
Retinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gammaHomo sapiens (human)0.0077
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1CHomo sapiens (human)0.265
cGMP-inhibited 3',5'-cyclic phosphodiesterase AHomo sapiens (human)1.34
Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11AHomo sapiens (human)1.3701
cAMP-specific 3',5'-cyclic phosphodiesterase 7BHomo sapiens (human)1.6601
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10AHomo sapiens (human)1.4883

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Cheng, C; Jiang, Y; Lou, H; Qiao, Y; Sun, B; Tan, J; Wu, Y; Xie, Z; Zhao, S; Zheng, H1

Other Studies

1 other study(ies) available for perlolyrine and vardenafil

ArticleYear
Discovery of furyl/thienyl β-carboline derivatives as potent and selective PDE5 inhibitors with excellent vasorelaxant effect.
    European journal of medicinal chemistry, 2018, Oct-05, Volume: 158

    Topics: Animals; Carbolines; Cyclic Nucleotide Phosphodiesterases, Type 5; Drug Design; Female; Humans; Male; Mesenteric Arteries; Molecular Docking Simulation; Phosphodiesterase 5 Inhibitors; Rats, Wistar; Structure-Activity Relationship; Vasodilator Agents

2018