periplogenin has been researched along with digitoxigenin in 22 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (18.18) | 18.7374 |
| 1990's | 1 (4.55) | 18.2507 |
| 2000's | 4 (18.18) | 29.6817 |
| 2010's | 9 (40.91) | 24.3611 |
| 2020's | 4 (18.18) | 2.80 |
| Authors | Studies |
|---|---|
| Itokawa, H; Kamano, Y; Katsuyama, M; Morita, H; Nogawa, T; Pettit, GR; Saito, K; Segawa, T; Takeya, K; Yamashita, A; Yukita, A | 1 |
| Banskota, AH; Kadota, S; Saiki, I; Tezuka, Y; Tran, QK; Tran, QL; Ueda, JY | 1 |
| Blair, IA; Harris, TM; Hellerqvist, CG; Inagami, T; Lam, SK; Phillips, D; Tamura, M; Wang, YF | 1 |
| REICHSTEIN, T; SPEISER, P | 1 |
| Kar, A; Panda, S | 2 |
| Han, N; Li, L; Sha, S; Tran, L; Wu, C; Xiao, B; Yang, J; Yin, J | 1 |
| REICHSTEIN, T; SPEISER, F | 1 |
| ELDERFIELD, RC; FRIED, J; UHLE, FC | 1 |
| ERNST, O; PLATTNER, PA; SEGRE, A | 1 |
| Chen, H; Gan, X; Gong, X; Zhao, C; Zhou, X | 1 |
| Bo, F; Chang, Y; Donkor, PO; Dou, T; Gao, X; He, J; Ouyang, H; Tu, Y; Wang, X | 1 |
| Azietaku, JT; Bo, F; Chang, Y; Dou, T; Gao, X; He, J; Liu, H; Ouyang, H; Tu, Y | 1 |
| Bao, YL; Huang, YX; Li, WL; Li, YX; Song, ZB; Sun, LG; Wang, Q; Yang, XG; Yu, CL; Zhang, WJ | 1 |
| Cao, X; Omari-Siaw, E; Tong, SS; Wang, Y; Wang, YW; Xu, WQ; Xu, XM; Yu, JN; Zhang, HY; Zheng, YY | 1 |
| Huber, U; Kammerer, DR; Knittel, DN; Lorenz, P; Stintzing, FC | 1 |
| Azietaku, JT; Chang, Y; Gao, X; He, J; Liu, H; Ouyang, H; Sun, M; Tang, Z; Wang, M; Zhang, D | 1 |
| Bauer, R; Kaltenegger, H; Kretschmer, N; Kunert, O; Leithner, A; Lohberger, B; Rinner, B; Stuendl, N; Wagner, S; Wohlmuther, J | 1 |
| Ji, W; Lee, SC; Liu, Y; Wang, L; Yang, Y; Zhang, Y | 1 |
| Guo, L; Huang, Z; Liang, G; Meng, C; Su, W; Wei, X; Wei, Y; Ye, H | 1 |
| Chen, H; Chen, Y; Dong, Z; Gu, T; Hu, Y; Jia, X; Liu, F; Liu, H; Liu, K; Liu, T; Wang, P; Wei, H; Yang, R; Zhao, J | 1 |
| Gao, Y; Li, Y; Wang, Q; Wang, S; Wang, W; Wei, M; Wu, J; Wu, S; Yang, W; Yu, X; Yuan, Z; Zhu, M | 1 |
22 other study(ies) available for periplogenin and digitoxigenin
| Article | Year |
|---|---|
QSAR evaluation of the Ch'an Su and related bufadienolides against the colchicine-resistant primary liver carcinoma cell line PLC/PRF/5(1).
Topics: Antineoplastic Agents; Bufanolides; Colchicine; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Humans; Liver Neoplasms; Models, Molecular; Quantitative Structure-Activity Relationship; Tumor Cells, Cultured | 2002 |
Constituents of the Vietnamese medicinal plant Streptocaulon juventas and their antiproliferative activity against the human HT-1080 fibrosarcoma cell line.
Topics: Cardenolides; Drug Screening Assays, Antitumor; Esterification; Fibrosarcoma; Humans; Hydrolysis; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Plants, Medicinal; Stereoisomerism; Tumor Cells, Cultured; Vietnam | 2003 |
Identification of two cardiac glycosides as Na(+)-pump inhibitors in rat urine and diet.
Topics: Analysis of Variance; Animal Feed; Animals; Brain; Cardiac Glycosides; Cell Membrane; Diet; Digitoxigenin; Glycosides; Humans; Hypertension, Renovascular; Magnetic Resonance Spectroscopy; Male; Mass Spectrometry; Molecular Structure; Rats; Rats, Sprague-Dawley; Reference Values; Sodium-Potassium-Exchanging ATPase | 1994 |
Configuration of the Periplogenin and the allo-Periplogenin.
Topics: Digitoxigenin | 1947 |
Periplogenin-3-O- -D-glucopyranosyl -(1-->6)- -D-glucopyaranosyl- -(1-->4) -D-cymaropyranoside, isolated from Aegle marmelos protects doxorubicin induced cardiovascular problems and hepatotoxicity in rats.
Topics: Aegle; Alanine Transaminase; alpha-Tocopherol; Animals; Antibiotics, Antineoplastic; Antioxidants; Body Weight; Cardiovascular Diseases; Catalase; Chemical and Drug Induced Liver Injury; Creatine Kinase, MB Form; Digitoxigenin; Disease Models, Animal; Dose-Response Relationship, Drug; Doxorubicin; Glutathione; Lipid Peroxidation; Lipids; Liver Diseases; Plant Leaves; Rats; Rats, Wistar; Superoxide Dismutase | 2009 |
Inhibitory activity of a phytochemically characterized fraction from Streptocaulon juventas on lung cancer in nude mice.
Topics: Animals; Antineoplastic Agents, Phytogenic; Apocynaceae; Cell Line, Tumor; Digitoxigenin; Lung Neoplasms; Mice; Mice, Nude; Molecular Structure; Neoplasms, Experimental; Plant Extracts; Xenograft Model Antitumor Assays | 2010 |
Configuration of the periplogenin and allo-periplogenins.
Topics: Digitoxigenin | 1947 |
Synthesis of glucosides of digitoxigenin, digoxigenin and periplogenin.
Topics: Digitoxigenin; Digoxigenin; Glucosides | 1947 |
About steroids and sex hormones; About the stereochemistry of strophanthidine and periplogenin.
Topics: Digitoxigenin; Strophanthidin | 1947 |
[Chemical constituents of Periploca forrestii].
Topics: Caffeic Acids; Chromatography, High Pressure Liquid; Digitoxigenin; Magnetic Resonance Spectroscopy; Periploca; Proanthocyanidins; Sterols; Triterpenes | 2009 |
Periplogenin, isolated from Lagenaria siceraria, ameliorates L-T₄-induced hyperthyroidism and associated cardiovascular problems.
Topics: Animals; Cardiovascular Diseases; Digitoxigenin; Humans; Hyperthyroidism; Lipid Peroxidation; Magnoliopsida; Plant Extracts; Random Allocation; Rats; Rats, Wistar; Thyroxine | 2011 |
A validated LC-MS/MS method for determination of periplogenin in rat plasma and its application in pharmacokinetic study.
Topics: Animals; Chromatography, Liquid; Digitoxigenin; Drug Stability; Linear Models; Male; Periploca; Plant Extracts; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Sensitivity and Specificity; Tandem Mass Spectrometry | 2015 |
A validated LC-MS/MS assay for the simultaneous determination of periplocin and its two metabolites, periplocymarin and periplogenin in rat plasma: Application to a pharmacokinetic study.
Topics: Acetonitriles; Administration, Oral; Animals; Calibration; Cardiac Glycosides; Chromatography, Liquid; Digitoxigenin; Formates; Limit of Detection; Male; Plasma; Quality Control; Rats; Rats, Sprague-Dawley; Saponins; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry | 2015 |
Periplogenin induces necroptotic cell death through oxidative stress in HaCaT cells and ameliorates skin lesions in the TPA- and IMQ-induced psoriasis-like mouse models.
Topics: Aminoquinolines; Animals; Cell Death; Cell Line; Cell Survival; Digitoxigenin; Disease Models, Animal; Female; Humans; Imiquimod; Mice; Mice, Inbred BALB C; Necrosis; Oxidative Stress; Psoriasis; Tetradecanoylphorbol Acetate | 2016 |
Tumor targeted delivery of octreotide-periplogenin conjugate: Synthesis, in vitro and in vivo evaluation.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Survival; Digitoxigenin; Drug Delivery Systems; Humans; Male; Mice; Neoplasms; Octreotide; Tissue Distribution; Tumor Burden | 2016 |
Characterization of the cardiac glycoside and lipid profiles of Strophanthus kombé Oliv. seeds.
Topics: Cardiac Glycosides; Chromatography, High Pressure Liquid; Digitoxigenin; Fatty Acids; Gas Chromatography-Mass Spectrometry; Linoleic Acid; Lipids; Mass Spectrometry; Molecular Structure; Oleic Acid; Phytosterols; Plant Extracts; Seeds; Strophanthidin; Strophanthus | 2016 |
Tissue distribution study of periplocin and its two metabolites in rats by a validated LC-MS/MS method.
Topics: Animals; Cardiac Glycosides; Chromatography, Liquid; Digitoxigenin; Linear Models; Male; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Saponins; Sensitivity and Specificity; Tandem Mass Spectrometry; Tissue Distribution | 2018 |
Periplocin, the most anti-proliferative constituent of Periploca sepium, specifically kills liposarcoma cells by death receptor mediated apoptosis.
Topics: Apoptosis; Cardiac Glycosides; Cell Line, Tumor; China; Digitoxigenin; Humans; Liposarcoma; Periploca; Plant Extracts; Plant Roots; Plants, Medicinal; Receptors, Death Domain; Saponins | 2018 |
Periplogenin Activates ROS-ER Stress Pathway to Trigger Apoptosis via BIP-eIF2α- CHOP and IRE1α-ASK1-JNK Signaling Routes.
Topics: Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Proliferation; Colonic Neoplasms; Digitoxigenin; Drug Discovery; Endoplasmic Reticulum; Endoribonucleases; Eukaryotic Initiation Factor-2; Gene Expression Regulation; Humans; MAP Kinase Kinase Kinase 5; MAP Kinase Signaling System; Periploca; Plant Extracts; Protein Serine-Threonine Kinases; Reactive Oxygen Species | 2021 |
Mechanism of Action of Periplogenin on Nasopharyngeal Carcinoma Based on Network Pharmacology and Experimental Study of Vitamin E Coupled with Periplogenin Self-Assembled Nano-Prodrug for Nasopharyngeal Carcinoma.
Topics: Digitoxigenin; Humans; Nasopharyngeal Carcinoma; Nasopharyngeal Neoplasms; Phosphatidylinositol 3-Kinases; Prodrugs; Vitamin E | 2020 |
Periplogenin suppresses the growth of esophageal squamous cell carcinoma in vitro and in vivo by targeting STAT3.
Topics: Aged; Aged, 80 and over; Apoptosis; Cell Line, Tumor; Cell Proliferation; Cell Survival; Digitoxigenin; Esophageal Neoplasms; Esophageal Squamous Cell Carcinoma; Female; Humans; Male; Middle Aged; Phosphorylation; Signal Transduction; STAT3 Transcription Factor; Survival Rate; Xenograft Model Antitumor Assays | 2021 |
Simultaneous determination of periplocin, periplocymarin, periplogenin, periplocoside M and periplocoside N of Cortex Periplocae in rat plasma and its application to a pharmacokinetic study.
Topics: Administration, Oral; Animals; Cardiac Glycosides; Chromatography, High Pressure Liquid; Digitoxigenin; Female; Male; Rats; Reproducibility of Results; Saponins; Tandem Mass Spectrometry | 2022 |