perindoprilat has been researched along with perindopril in 34 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (11.76) | 18.7374 |
| 1990's | 18 (52.94) | 18.2507 |
| 2000's | 6 (17.65) | 29.6817 |
| 2010's | 2 (5.88) | 24.3611 |
| 2020's | 4 (11.76) | 2.80 |
| Authors | Studies |
|---|---|
| Funakoshi, J; Kakumoto, M; Okumura, K; Sakaeda, T; Takara, K; Tanigawara, Y | 1 |
| Ali, A; Desche, P; Dratwa, M; Genissel, P; Resplandy, G; Sennesael, J; Slovic, D; Sweny, P; Vandenburg, M | 1 |
| Bree, F; Nguyen, P; Resplandy, G; Tillement, JP; Urien, S | 1 |
| Baumal, JY; Bouchet, JP; Damien, G; Jaguelin-Guinamant, S; Lambert, PH; Marchand, B; Portevin, B; Rémond, G; Vincent, M; Volland, JP | 1 |
| Funck-Brentano, C; Grangé, JD; Jaillon, P; Midavaine, M; Resplandy, G; Thiollet, M | 1 |
| Cubela, R; Jackson, B; Johnston, CI; Mendelsohn, FA; Pupic, V | 1 |
| De Broe, ME; Genissel, PM; Thomas, JR; Verpooten, GA | 1 |
| Genissel, P; Resplandy, G | 1 |
| Arts, CJ; Bertrand, M; de Bie, AT; Floor, W; Resplandy, G; van den Berg, H | 1 |
| Backhouse, CI; Brown, CL; Grippat, JC; Santoni, JP | 1 |
| Martin, P; Massol, J; Puech, AJ; Scalbert, E | 1 |
| Ammoury, N; Devissaguet, JP; Devissaguet, M; Perret, L | 1 |
| Lees, KR; Reid, JL | 1 |
| Hughes, DM; Lees, KR; McNeill, CA; Reid, JL | 1 |
| Devissaguet, M; Padieu, P; Tsaconas, C | 1 |
| Green, ST; Lees, KR; Reid, JL | 1 |
| Anderson, PJ; Critchley, JA; Resplandy, G; Tomlinson, B | 1 |
| Campbell, GR; Campbell, JH; Fennessy, PA | 1 |
| Lees, KR; MacFadyen, RJ; Reid, JL; Squire, IB | 2 |
| Guérin, A; London, G; Marchais, S; Resplandy, G; Taillard, F | 1 |
| Devlin, A; Lees, KR; MacFayden, RJ; Reid, JL; Squire, IB | 1 |
| Dusting, GJ; Hickey, H; Hyland, R; Makdissi, M; Wilks, D | 1 |
| Bellissant, E; Giudicelli, JF | 1 |
| Hiromi, Y; Kato, K; Kawahara, H; Muraoka, I; Nabeshima, T; Seno, H; Takasu, R; Yamada, S | 1 |
| Ito, A; Komune, S; Kuratomi, Y; Masuda, M; Nakagawa, T; Nakashima, T; Yasumatsu, R | 1 |
| Aarons, L; Parker, E; Resplandy, G; Rowland, M | 1 |
| Jain, DS; Pande, UC; Sanyal, M; Shrivastav, P; Subbaiah, G | 1 |
| Georgakakou, S; Kazanis, M; Panderi, I | 1 |
| Garg, S; Gerber, C; Leggett, C; Lwin, EMP; Ritchie, U; Song, Y; Turner, S | 1 |
| Cai, H; Gu, Y; Guo, J; He, B; Huang, X; Liu, X; Tan, X; Wei, W; Yang, H; Yin, Y; Zhang, B; Zhou, X | 1 |
| Garg, S; Gerber, JP; Hague, WM; Leggett, C; Lwin, EMP; Ritchie, U; Song, Y; Stark, M; Turner, S; Upton, R | 1 |
| Chen, R; Cui, X; Gao, H; Lauruol, P; Wang, H; Wang, Y; Zhang, Y; Zheng, X | 1 |
| Abbas, SS; Eid, SM; Elghobashy, MR; Hassan, SA; Moustafa, AA; Nashat, NW | 1 |
1 review(s) available for perindoprilat and perindopril
| Article | Year |
|---|---|
Pharmacokinetics of perindopril in high-risk populations.
Topics: Aged; Aged, 80 and over; Angiotensin-Converting Enzyme Inhibitors; Heart Failure; Humans; Indoles; Kidney Failure, Chronic; Liver Diseases; Perindopril | 1991 |
12 trial(s) available for perindoprilat and perindopril
| Article | Year |
|---|---|
The effect of perindopril and hydrochlorothiazide alone and in combination on blood pressure and on the renin-angiotensin system in hypertensive subjects.
Topics: Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Indoles; Male; Middle Aged; Perindopril; Renin-Angiotensin System | 1990 |
Pharmacokinetics of perindopril and its metabolites in healthy volunteers.
Topics: Administration, Oral; Adult; Biological Availability; Female; Glucuronates; Half-Life; Humans; Indoles; Injections, Intravenous; Male; Perindopril; Reference Values | 1990 |
Effects of intravenous S-9780, an angiotensin-converting enzyme inhibitor, in normotensive subjects.
Topics: Adolescent; Adult; Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Catecholamines; Double-Blind Method; Female; Heart Rate; Humans; Indoles; Kinetics; Male; Perindopril; Random Allocation; Renin | 1987 |
Pharmacokinetics of perindopril: therapeutic consequences.
Topics: Adolescent; Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; Clinical Trials as Topic; Double-Blind Method; Humans; Hypertension; Indoles; Liver Cirrhosis; Male; Middle Aged; Perindopril; Random Allocation | 1989 |
Influence of age on the pharmacokinetics and pharmacodynamics of perindopril.
Topics: Adult; Age Factors; Aged; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Female; Humans; Indoles; Male; Peptidyl-Dipeptidase A; Perindopril | 1988 |
Blood pressure response to the first dose of angiotensin-converting enzyme inhibitors in congestive heart failure.
Topics: Aged; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Captopril; Double-Blind Method; Enalapril; Enalaprilat; Female; Heart Failure; Humans; Indoles; Male; Middle Aged; Perindopril; Prodrugs | 1993 |
Angiotensin-converting enzyme inhibitors in heart failure: blood pressure changes after the first dose.
Topics: Acetylcholinesterase; Aged; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Captopril; Double-Blind Method; Enalapril; Enalaprilat; Female; Heart Failure; Humans; Indoles; Male; Middle Aged; Perindopril | 1993 |
Differing early blood pressure and renin-angiotensin system responses to the first dose of angiotensin-converting enzyme inhibitors in congestive heart failure.
Topics: Aged; Aged, 80 and over; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Double-Blind Method; Enalapril; Female; Heart Failure; Heart Rate; Humans; Indoles; Male; Middle Aged; Perindopril; Renin; Renin-Angiotensin System | 1996 |
Pharmacokinetic-pharmacodynamic model for perindoprilat regional haemodynamic effects in healthy volunteers and in congestive heart failure patients.
Topics: Adult; Angiotensin-Converting Enzyme Inhibitors; Brachial Artery; Cardiovascular Agents; Cross-Over Studies; Double-Blind Method; Female; Heart Failure; Hemodynamics; Humans; Indoles; Male; Middle Aged; Peptidyl-Dipeptidase A; Perindopril; Vascular Resistance | 2001 |
Elimination kinetics of quinaprilat and perindoprilat in hypertensive patients with renal failure on haemodialysis.
Topics: Administration, Oral; Adult; Angiotensin-Converting Enzyme Inhibitors; Chromatography, High Pressure Liquid; Half-Life; Humans; Hypertension; Indoles; Male; Metabolic Clearance Rate; Middle Aged; Perindopril; Quinapril; Renal Dialysis; Renal Insufficiency; Tetrahydroisoquinolines | 2003 |
A UPLC-MS/MS method for quantification of perindopril and perindoprilat and applied in a bioequivalence study for their pharmacokinetic parameter measurement
.
Topics: Chromatography, High Pressure Liquid; Cross-Over Studies; Female; Humans; Indoles; Male; Perindopril; Reproducibility of Results; Tablets; Tandem Mass Spectrometry; Therapeutic Equivalency | 2020 |
Simultaneous determination of indapamide, perindopril and its active metabolite perindoprilat in human plasma using UPLC-MS/MS method.
Topics: Chromatography, High Pressure Liquid; Cross-Over Studies; Drug Combinations; Humans; Indapamide; Indoles; Linear Models; Male; Perindopril; Reproducibility of Results; Sensitivity and Specificity; Solid Phase Extraction; Tandem Mass Spectrometry | 2021 |
21 other study(ies) available for perindoprilat and perindopril
| Article | Year |
|---|---|
Interaction of digoxin with antihypertensive drugs via MDR1.
Topics: Animals; Antihypertensive Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Cells, Cultured; Digoxin; Drug Interactions; Humans; Time Factors | 2002 |
The pharmacokinetics of perindopril and its effects on serum angiotensin converting enzyme activity in hypertensive patients with chronic renal failure.
Topics: Aged; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Female; Humans; Hypertension; Indoles; Kidney Failure, Chronic; Male; Middle Aged; Peptidyl-Dipeptidase A; Perindopril | 1992 |
Specific and high affinity binding of perindoprilat, but not of perindopril to blood ACE.
Topics: Angiotensin-Converting Enzyme Inhibitors; Blood Proteins; Drug Interactions; Erythrocytes; Humans; Indoles; Kinetics; Liver Failure; Peptidyl-Dipeptidase A; Perindopril; Protein Binding; Renal Insufficiency; Sensitivity and Specificity; Serum Albumin | 1992 |
Synthesis and ACE inhibitory activity of the stereoisomers of perindopril (S 9490) and perindoprilate (S 9780).
Topics: Administration, Oral; Angiotensin I; Angiotensin-Converting Enzyme Inhibitors; Animals; Dogs; In Vitro Techniques; Indoles; Injections, Intravenous; Magnetic Resonance Spectroscopy; Mass Spectrometry; Perindopril; Stereoisomerism; Substrate Specificity | 1992 |
The pharmacokinetics of perindopril in patients with liver cirrhosis.
Topics: Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; Female; Humans; Indoles; Liver Cirrhosis; Liver Cirrhosis, Alcoholic; Male; Middle Aged; Perindopril | 1992 |
Acute and chronic effects of perindopril on tissue angiotensin converting enzyme activity.
Topics: Angiotensin I; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Indoles; Male; Peptidyl-Dipeptidase A; Perindopril; Rats; Rats, Inbred Strains; Tissue Distribution | 1991 |
Single dose pharmacokinetics of perindopril and its metabolites in hypertensive patients with various degrees of renal insufficiency.
Topics: Adult; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Female; Glucuronates; Half-Life; Humans; Hypertension, Renal; Indoles; Kidney Failure, Chronic; Male; Middle Aged; Peptidyl-Dipeptidase A; Perindopril; Renal Dialysis | 1991 |
A new radioimmunoassay for the determination of the angiotensin-converting enzyme inhibitor perindopril and its active metabolite in plasma and urine: advantages of a lysine derivative as immunogen to improve the assay specificity.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Antibodies; Antibody Specificity; Antihypertensive Agents; Cross Reactions; Immunization; Indoles; Perindopril; Protein Binding; Rabbits; Radioimmunoassay; Sensitivity and Specificity | 1991 |
Involvement of angiotensin-converting enzyme inhibition in reversal of helpless behavior evoked by perindopril in rats.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Carboxypeptidases; Electroshock; Helplessness, Learned; Indoles; Male; Peptidyl-Dipeptidase A; Perindopril; Rats; Rats, Inbred Strains | 1990 |
Gas chromatography-mass spectrometry of perindopril and its active free metabolite, an angiotensin convertase inhibitor: choice of derivatives and ionization modes.
Topics: Angiotensin-Converting Enzyme Inhibitors; Chemical Phenomena; Chemistry; Gas Chromatography-Mass Spectrometry; Humans; Indoles; Perindopril | 1989 |
Comparison of the pharmacokinetics and pharmacodynamics of oral doses of perindopril in normotensive Chinese and Caucasian volunteers.
Topics: Administration, Oral; Aldosterone; Analysis of Variance; Angiotensin I; Angiotensin-Converting Enzyme Inhibitors; Asian People; Blood Pressure; Blood Proteins; Female; Heart Rate; Humans; Indoles; Male; Peptidyl-Dipeptidase A; Perindopril; Protein Binding; Renin; White People | 1995 |
Perindopril inhibits both the development of atherosclerosis in the cholesterol-fed rabbit and lipoprotein binding to smooth muscle cells in culture.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Aorta, Thoracic; Arteriosclerosis; Carotid Arteries; Cell Division; Cells, Cultured; Cholesterol, Dietary; Collagen; Female; Indoles; Lipoproteins; Male; Muscle, Smooth, Vascular; Perindopril; Rabbits | 1994 |
The effect of haemodialysis on the pharmacokinetics of perindoprilat after long-term perindopril.
Topics: Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Female; Heart Rate; Humans; Indoles; Male; Middle Aged; Perindopril; Radioimmunoassay; Renal Dialysis; Ultrafiltration | 1993 |
Perindopril treatment prevents the loss of endothelial nitric oxide function and development of neo-intima in rabbits.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Arteriosclerosis; Carotid Arteries; Disease Models, Animal; Endothelium, Vascular; Hemodynamics; In Vitro Techniques; Indoles; Nitric Oxide; Peptidyl-Dipeptidase A; Perindopril; Rabbits; Serotonin; Vasoconstriction; Vasodilation | 1996 |
Effects of the angiotensin-I converting enzyme inhibitor perindopril on tumor growth and angiogenesis in head and neck squamous cell carcinoma cells.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Cell Line, Tumor; Female; Head and Neck Neoplasms; Immunoenzyme Techniques; Immunohistochemistry; Indoles; Mice; Mice, Inbred BALB C; Neovascularization, Pathologic; Perindopril; Promoter Regions, Genetic; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Vascular Endothelial Growth Factor A | 2004 |
The pharmacokinetics of perindoprilat in normal volunteers and patients: influence of age and disease state.
Topics: Administration, Oral; Adult; Age Factors; Aged; Aged, 80 and over; Angiotensin-Converting Enzyme Inhibitors; Clinical Trials, Phase I as Topic; Clinical Trials, Phase II as Topic; Creatinine; Dose-Response Relationship, Drug; Female; Heart Failure; Humans; Indoles; Injections, Intravenous; Male; Middle Aged; Models, Biological; Perindopril; Renal Insufficiency | 2005 |
First LC-MS/MS electrospray ionization validated method for the quantification of perindopril and its metabolite perindoprilat in human plasma and its application to bioequivalence study.
Topics: Angiotensin-Converting Enzyme Inhibitors; Humans; Indoles; Perindopril; Reproducibility of Results; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization; Therapeutic Equivalency | 2006 |
Hydrophilic interaction liquid chromatography/positive ion electrospray ionization mass spectrometry method for the quantification of perindopril and its main metabolite in human plasma.
Topics: Angiotensin-Converting Enzyme Inhibitors; Chromatography, Liquid; Humans; Indoles; Methods; Perindopril; Reproducibility of Results; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry | 2010 |
A new LC-MS/MS bioanalytical method for perindopril and perindoprilat in human plasma and milk.
Topics: Angiotensin-Converting Enzyme Inhibitors; Breast Feeding; Chromatography, Liquid; Female; Humans; Indoles; Limit of Detection; Milk, Human; Perindopril; Reproducibility of Results; Tandem Mass Spectrometry | 2017 |
Perindopril in Breast Milk and Determination of Breastfed Infant Exposure: A Prospective Observational Study.
Topics: Adult; Angiotensin-Converting Enzyme Inhibitors; Breast Feeding; Female; Humans; Indoles; Infant; Male; Middle Aged; Milk, Human; Perindopril; Prospective Studies; Young Adult | 2020 |
Optimization of localized surface plasmon resonance hot spots in surface-enhanced infrared absorption spectroscopy aluminum substrate as an optical sensor coupled to chemometric tools for the purity assay of quinary mixtures.
Topics: Aluminum; Bisoprolol; Citric Acid; Drug Contamination; Indoles; Limit of Detection; Metal Nanoparticles; Perindopril; Silver; Spectrophotometry, Infrared; Surface Plasmon Resonance; Tablets | 2021 |