perillic acid has been researched along with perillyl alcohol in 15 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (13.33) | 18.2507 |
| 2000's | 5 (33.33) | 29.6817 |
| 2010's | 5 (33.33) | 24.3611 |
| 2020's | 3 (20.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, GZ; Luján, HD; Mowatt, MR; Nash, TE | 1 |
| Bardon, S; Martel, P; Picard, K | 1 |
| Boon, PJ; Mulder, GJ; van der Boon, D | 1 |
| Adams, A; Gallo, JM; Halberr, T; Hudes, GR; Langer, CJ; Litwin, S; McCauley, RA; Qian, M; Ranganathan, S; Szarka, CE; Weiner, LM; Yeslow, G | 1 |
| Bardon, S; Fournel, S; Foussard, V; Loubat, A | 1 |
| Daneri-Navarro, A; Del Toro-Arreola, A; Del Toro-Arreola, S; Flores-Torales, E; Guadalupe Ramirez-Dueñas, M; Torres-Lozano, C; Tostado-Pelayo, K | 1 |
| Carper, SW; Elegbede, A; Pierre, KJ; Wang, RC; Yeruva, L | 1 |
| Amiot, A; Duelund, L; Fillon, A; Mouritsen, OG | 1 |
| Bühler, B; Cornelissen, S; Julsing, MK; Riechert, O; Schmid, A; Volmer, J | 1 |
| Burth, P; da Silva, CI; de Amorim, LM; de Castro-Faria-Neto, HC; de Souza e Souza, KF; Diniz, LP; Faria, MV; Freire, AS; Garcia, DG; Gomes, FC; Gonçalves-de-Albuquerque, CF; Santelli, RE; Silva, AR | 1 |
| Göen, T; Schmidt, L | 1 |
| Adu-Frimpong, M; Mukhtar, YM; Xu, X; Yu, J | 1 |
| Amorim, LF; Bloom, DC; Fragel, LM; Mello, CP; Paixão, IP; Quirico-Santos, T; Silva, VG | 1 |
| Boaventura, GT; Chen, TC; Cho, HY; Da Fonseca, CO; de Lima, DC; Rodrigues, SV; Schönthal, AH | 1 |
| da Fonseca, CO; da Silva Santos, J; Diedrich, C; Khalil, NM; Machado, CS; Mainardes, RM | 1 |
1 review(s) available for perillic acid and perillyl alcohol
| Article | Year |
|---|---|
Biochemical significance of limonene and its metabolites: future prospects for designing and developing highly potent anticancer drugs.
Topics: Cyclohexenes; Drug Design; Humans; Limonene; Methyl Ethers; Monoterpenes; Neoplasms | 2018 |
1 trial(s) available for perillic acid and perillyl alcohol
| Article | Year |
|---|---|
Phase I pharmacokinetic trial of perillyl alcohol (NSC 641066) in patients with refractory solid malignancies.
Topics: Administration, Oral; Adult; Aged; Antineoplastic Agents, Phytogenic; Cyclohexenes; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Humans; Leukocytes, Mononuclear; Male; Middle Aged; Monoterpenes; Neoplasms; Proto-Oncogene Proteins p21(ras); Terpenes; Tumor Cells, Cultured | 2000 |
13 other study(ies) available for perillic acid and perillyl alcohol
| Article | Year |
|---|---|
Isoprenylation of proteins in the protozoan Giardia lamblia.
Topics: Acetylcysteine; Animals; Cholesterol; Cyclohexenes; Dolichols; Giardia lamblia; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Limonene; Lipid Metabolism; Lovastatin; Mevalonic Acid; Monoterpenes; Protein Prenylation; Proto-Oncogene Proteins p21(ras); Protozoan Proteins; Terpenes; Ubiquinone | 1995 |
Monoterpenes inhibit cell growth, cell cycle progression, and cyclin D1 gene expression in human breast cancer cell lines.
Topics: Antineoplastic Agents; Breast Neoplasms; Cell Cycle; Cell Division; Cyclin D1; Cyclohexenes; Disease Progression; Female; Gene Expression Regulation, Neoplastic; Humans; Limonene; Monoterpenes; Terpenes; Tumor Cells, Cultured | 1998 |
Cytotoxicity and biotransformation of the anticancer drug perillyl alcohol in PC12 cells and in the rat.
Topics: Animals; Antineoplastic Agents; Bile; Biotransformation; Cyclohexenes; Glutathione; Liver; Male; Monoterpenes; PC12 Cells; Rats; Rats, Wistar; Terpenes | 2000 |
Monoterpenes inhibit proliferation of human colon cancer cells by modulating cell cycle-related protein expression.
Topics: Antineoplastic Agents; Cell Division; Colonic Neoplasms; Cyclin D1; Cyclin E; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Cyclohexenes; Dose-Response Relationship, Drug; G1 Phase; Gene Expression; Humans; Monoterpenes; RNA, Messenger; S Phase; Terpenes; Tumor Cells, Cultured | 2002 |
Effect of D-limonene on immune response in BALB/c mice with lymphoma.
Topics: Animals; Chemotaxis; Cyclohexenes; Dinitrofluorobenzene; Escherichia coli; Female; Hypersensitivity, Delayed; Immunization; Immunologic Factors; In Vitro Techniques; Leukemia L5178; Limonene; Lymphocyte Activation; Macrophages, Peritoneal; Mice; Mice, Inbred BALB C; Monoterpenes; Nitric Oxide; T-Lymphocyte Subsets; Terpenes | 2005 |
Perillyl alcohol and perillic acid induced cell cycle arrest and apoptosis in non small cell lung cancer cells.
Topics: Antineoplastic Agents; Apoptosis; bcl-2-Associated X Protein; Blotting, Western; Carcinoma, Non-Small-Cell Lung; Caspase 3; Cell Cycle; Cell Line, Tumor; Cell Survival; Cisplatin; Cyclin-Dependent Kinase Inhibitor p21; Cyclohexenes; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Drug Synergism; Enzyme-Linked Immunosorbent Assay; Flow Cytometry; Humans; Inhibitory Concentration 50; Lung Neoplasms; Monoterpenes; Proto-Oncogene Proteins c-bcl-2; Radiation, Ionizing | 2007 |
Influence of the active compounds of Perilla frutescens leaves on lipid membranes.
Topics: Cell Membrane; Cyclohexenes; Dimyristoylphosphatidylcholine; Limonene; Membrane Lipids; Models, Molecular; Molecular Structure; Monoterpenes; Perilla frutescens; Plant Leaves; Plants, Medicinal; Terpenes | 2012 |
Whole-cell-based CYP153A6-catalyzed (S)-limonene hydroxylation efficiency depends on host background and profits from monoterpene uptake via AlkL.
Topics: Bacterial Outer Membrane Proteins; Bioreactors; Cyclohexenes; Cytochrome P-450 Enzyme System; Escherichia coli; Hydroxylation; Isoenzymes; Limonene; Monoterpenes; Pseudomonas putida; Terpenes | 2013 |
Na/K-ATPase as a target for anticancer drugs: studies with perillyl alcohol.
Topics: Animals; Antineoplastic Agents; Apoptosis; beta-Cyclodextrins; Cell Line, Tumor; Cell Survival; Cyclohexenes; Cytokines; Dasatinib; Enzyme Activation; Humans; JNK Mitogen-Activated Protein Kinases; Mice; Models, Biological; Molecular Targeted Therapy; Monoterpenes; p38 Mitogen-Activated Protein Kinases; Sodium-Potassium-Exchanging ATPase | 2015 |
R-Limonene metabolism in humans and metabolite kinetics after oral administration.
Topics: Administration, Oral; Adult; Cyclohexane Monoterpenes; Cyclohexenes; Female; Gas Chromatography-Mass Spectrometry; Half-Life; Humans; Limonene; Male; Monoterpenes; Terpenes | 2017 |
Perillyl alcohol and perillic acid exert efficient action upon HSV-1 maturation and release of infective virus.
Topics: Animals; Antiviral Agents; Blotting, Western; Chlorocebus aethiops; Cyclohexenes; Herpesvirus 1, Human; Monoterpenes; Real-Time Polymerase Chain Reaction; Vero Cells; Viral Plaque Assay; Virus Shedding | 2020 |
Simultaneous measurement of perillyl alcohol and its metabolite perillic acid in plasma and lung after inhalational administration in Wistar rats.
Topics: Administration, Inhalation; Animals; Antineoplastic Agents; Cell Line, Tumor; Chromatography, High Pressure Liquid; Cyclohexenes; Drug Monitoring; Humans; Lung; Lung Neoplasms; Male; Monoterpenes; Rats; Rats, Wistar; Tissue Distribution | 2020 |
Intranasal administration of perillyl alcohol-loaded nanoemulsion and pharmacokinetic study of its metabolite perillic acid in plasma and brain of rats using ultra-performance liquid chromatography/tandem mass spectrometry.
Topics: Administration, Intranasal; Animals; Brain Chemistry; Chromatography, High Pressure Liquid; Cyclohexenes; Emulsions; Limit of Detection; Linear Models; Monoterpenes; Nanostructures; Rats; Reproducibility of Results; Tandem Mass Spectrometry | 2021 |