perifosine has been researched along with dacarbazine in 3 studies
| Studies (perifosine) | Trials (perifosine) | Recent Studies (post-2010) (perifosine) | Studies (dacarbazine) | Trials (dacarbazine) | Recent Studies (post-2010) (dacarbazine) |
|---|---|---|---|---|---|
| 245 | 31 | 140 | 7,556 | 1,463 | 3,429 |
| Protein | Taxonomy | perifosine (IC50) | dacarbazine (IC50) |
|---|---|---|---|
| Matrix metalloproteinase-9 | Homo sapiens (human) | 0.556 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (66.67) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Holland, EC; Momota, H; Nerio, E | 1 |
| Beijnen, JH; de Vries, NA; van Tellingen, O | 1 |
| Cruz, R; Figg, WD; League-Pascual, JC; Lester-McCully, CM; Peer, CJ; Rodgers, L; Ronner, L; Shandilya, S; Warren, KE | 1 |
1 review(s) available for perifosine and dacarbazine
| Article | Year |
|---|---|
High-grade glioma mouse models and their applicability for preclinical testing.
Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Biomarkers, Tumor; Blood-Brain Barrier; Dacarbazine; Disease Models, Animal; Genetic Engineering; Glioblastoma; Mice; Phosphorylcholine; Prognosis; Temozolomide; Transplantation, Heterologous | 2009 |
2 other study(ies) available for perifosine and dacarbazine
| Article | Year |
|---|---|
Perifosine inhibits multiple signaling pathways in glial progenitors and cooperates with temozolomide to arrest cell proliferation in gliomas in vivo.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; CDC2-CDC28 Kinases; Cell Growth Processes; Cell Line, Tumor; Cyclin-Dependent Kinase 2; Dacarbazine; Dose-Response Relationship, Drug; Drug Synergism; G1 Phase; G2 Phase; Glioma; Humans; Mice; Mice, Transgenic; Phosphorylcholine; Platelet-Derived Growth Factor; Protein Kinase Inhibitors; Protein Kinases; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Signal Transduction; Temozolomide; TOR Serine-Threonine Kinases; Xenograft Model Antitumor Assays | 2005 |
Plasma and cerebrospinal fluid pharmacokinetics of select chemotherapeutic agents following intranasal delivery in a non-human primate model.
Topics: Administration, Intranasal; Animals; Antineoplastic Agents; Blood-Brain Barrier; Dacarbazine; Disease Models, Animal; Macaca mulatta; Male; Nasal Absorption; Phosphorylcholine; Temozolomide; Valproic Acid | 2017 |