perifosine has been researched along with cyclopamine in 1 studies
| Studies (perifosine) | Trials (perifosine) | Recent Studies (post-2010) (perifosine) | Studies (cyclopamine) | Trials (cyclopamine) | Recent Studies (post-2010) (cyclopamine) |
|---|---|---|---|---|---|
| 245 | 31 | 140 | 658 | 0 | 343 |
| Protein | Taxonomy | perifosine (IC50) | cyclopamine (IC50) |
|---|---|---|---|
| Integrin beta-1 | Homo sapiens (human) | 1.312 | |
| Integrin alpha-4 | Homo sapiens (human) | 1.312 | |
| Smoothened homolog | Mus musculus (house mouse) | 1.271 | |
| Sonic hedgehog protein | Homo sapiens (human) | 0.6 | |
| Sonic hedgehog protein | Mus musculus (house mouse) | 0.7373 | |
| Smoothened homolog | Homo sapiens (human) | 0.2147 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, X; Fan, Y; Hao, W; Hou, X; Jin, Y; Liu, F; Ma, A; Pang, T; Song, Z; Wang, W; Wang, Y; Zhang, P | 1 |
1 other study(ies) available for perifosine and cyclopamine
| Article | Year |
|---|---|
Inhibition of hedgehog signaling by GANT58 induces apoptosis and shows synergistic antitumor activity with AKT inhibitor in acute T cell leukemia cells.
Topics: Antineoplastic Agents; Apoptosis; Drug Screening Assays, Antitumor; Drug Synergism; Hedgehog Proteins; Humans; Jurkat Cells; MAP Kinase Signaling System; Oxadiazoles; Phosphorylcholine; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma; Proto-Oncogene Proteins c-akt; Pyridines; Thiophenes; Transcription Factors; Veratrum Alkaloids; Zinc Finger Protein GLI1 | 2014 |