perifosine has been researched along with bms 387032 in 3 studies
| Studies (perifosine) | Trials (perifosine) | Recent Studies (post-2010) (perifosine) | Studies (bms 387032) | Trials (bms 387032) | Recent Studies (post-2010) (bms 387032) |
|---|---|---|---|---|---|
| 245 | 31 | 140 | 76 | 3 | 56 |
| Protein | Taxonomy | perifosine (IC50) | bms 387032 (IC50) |
|---|---|---|---|
| Cyclin-T1 | Homo sapiens (human) | 0.0103 | |
| G2/mitotic-specific cyclin-B2 | Homo sapiens (human) | 0.48 | |
| G1/S-specific cyclin-E2 | Homo sapiens (human) | 0.048 | |
| Vitamin K-dependent protein C | Homo sapiens (human) | 0.264 | |
| Cyclin-dependent kinase 1 | Homo sapiens (human) | 0.48 | |
| Cyclin-dependent kinase 4 | Homo sapiens (human) | 0.7538 | |
| G2/mitotic-specific cyclin-B1 | Homo sapiens (human) | 0.48 | |
| Cyclin-A2 | Homo sapiens (human) | 0.0427 | |
| G1/S-specific cyclin-D1 | Homo sapiens (human) | 0.925 | |
| G1/S-specific cyclin-E1 | Homo sapiens (human) | 0.046 | |
| Cyclin-dependent kinase 2 | Homo sapiens (human) | 0.0426 | |
| G1/S-specific cyclin-D2 | Homo sapiens (human) | 0.925 | |
| G1/S-specific cyclin-D3 | Homo sapiens (human) | 0.925 | |
| Cannabinoid receptor 2 | Mus musculus (house mouse) | 0.062 | |
| Cyclin-dependent kinase 7 | Homo sapiens (human) | 0.0772 | |
| Cyclin-dependent kinase 9 | Homo sapiens (human) | 0.1078 | |
| Cyclin-H | Homo sapiens (human) | 0.0823 | |
| CDK-activating kinase assembly factor MAT1 | Homo sapiens (human) | 0.1027 | |
| Cyclin-A1 | Homo sapiens (human) | 0.021 | |
| Cyclin-dependent-like kinase 5 | Homo sapiens (human) | 0.34 | |
| Cyclin-dependent kinase 5 activator 1 | Homo sapiens (human) | 0.34 | |
| G2/mitotic-specific cyclin-B3 | Homo sapiens (human) | 0.48 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Davis, MI; Khan, J; Li, SQ; Patel, PR; Shen, M; Sun, H; Thomas, CJ | 1 |
| Aiche, S; Bassermann, F; Becker, W; Canevari, G; Casale, E; Depaolini, SR; Ehrlich, HC; Felder, ER; Feuchtinger, A; Garz, AK; Gohlke, BO; Götze, K; Greif, PA; Hahne, H; Heinzlmeir, S; Helm, D; Huenges, J; Jeremias, I; Kayser, G; Klaeger, S; Koch, H; Koenig, PA; Kramer, K; Kuster, B; Médard, G; Meng, C; Petzoldt, S; Polzer, H; Preissner, R; Qiao, H; Reinecke, M; Reiter, K; Rueckert, L; Ruland, J; Ruprecht, B; Schlegl, J; Schmidt, T; Schneider, S; Schoof, M; Spiekermann, K; Tõnisson, N; Vick, B; Vooder, T; Walch, A; Wilhelm, M; Wu, Z; Zecha, J; Zolg, DP | 1 |
| Jin, Y; Liu, H; Meng, H; Qian, W; Yang, C; Yang, X; You, L | 1 |
3 other study(ies) available for perifosine and bms 387032
| Article | Year |
|---|---|
Identification of potent Yes1 kinase inhibitors using a library screening approach.
Topics: Binding Sites; Cell Line; Cell Survival; Drug Design; Humans; Hydrogen Bonding; Molecular Docking Simulation; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-yes; Small Molecule Libraries; Structure-Activity Relationship | 2013 |
The target landscape of clinical kinase drugs.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cytokines; Drug Discovery; fms-Like Tyrosine Kinase 3; Humans; Leukemia, Myeloid, Acute; Lung Neoplasms; Mice; Molecular Targeted Therapy; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Proteomics; Xenograft Model Antitumor Assays | 2017 |
SNS-032 inhibits mTORC1/mTORC2 activity in acute myeloid leukemia cells and has synergistic activity with perifosine against Akt.
Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Blotting, Western; Cell Proliferation; Drug Synergism; Enzyme-Linked Immunosorbent Assay; Female; Flow Cytometry; Humans; Leukemia, Myeloid, Acute; Male; Mechanistic Target of Rapamycin Complex 1; Mechanistic Target of Rapamycin Complex 2; Multiprotein Complexes; Oxazoles; Phosphorylation; Phosphorylcholine; Proto-Oncogene Proteins c-akt; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Thiazoles; TOR Serine-Threonine Kinases; Tumor Cells, Cultured | 2013 |