perifosine has been researched along with abt-737 in 2 studies
| Studies (perifosine) | Trials (perifosine) | Recent Studies (post-2010) (perifosine) | Studies (abt-737) | Trials (abt-737) | Recent Studies (post-2010) (abt-737) |
|---|---|---|---|---|---|
| 245 | 31 | 140 | 632 | 0 | 484 |
| Protein | Taxonomy | perifosine (IC50) | abt-737 (IC50) |
|---|---|---|---|
| Bcl-2-like protein 11 | Homo sapiens (human) | 0.002 | |
| Apoptosis regulator Bcl-2 | Homo sapiens (human) | 0.0206 | |
| Alpha-1B adrenergic receptor | Rattus norvegicus (Norway rat) | 0.0003 | |
| Alpha-2B adrenergic receptor | Rattus norvegicus (Norway rat) | 0.0003 | |
| Alpha-2C adrenergic receptor | Rattus norvegicus (Norway rat) | 0.0003 | |
| Alpha-2A adrenergic receptor | Rattus norvegicus (Norway rat) | 0.0003 | |
| Adenosine receptor A2a | Rattus norvegicus (Norway rat) | 0.02 | |
| BH3-interacting domain death agonist | Homo sapiens (human) | 0.0485 | |
| Apoptosis regulator BAX | Homo sapiens (human) | 0.023 | |
| Bcl-2-like protein 1 | Homo sapiens (human) | 0.0207 | |
| Induced myeloid leukemia cell differentiation protein Mcl-1 | Homo sapiens (human) | 0.0248 | |
| Aspartyl/asparaginyl beta-hydroxylase | Homo sapiens (human) | 3.44 | |
| Bcl-2 homologous antagonist/killer | Homo sapiens (human) | 0.0335 | |
| Bcl-2-like protein 2 | Homo sapiens (human) | 0.0335 | |
| Bcl-2-binding component 3, isoforms 1/2 | Homo sapiens (human) | 0.0003 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 1 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Shen, J; Xu, L; Zhao, Q | 1 |
| Adamová, B; Beneš, P; Navrátilová, J; Pokludová, J; Říhová, K; Šmarda, J | 1 |
2 other study(ies) available for perifosine and abt-737
| Article | Year |
|---|---|
Perifosine and ABT-737 synergistically inhibit lung cancer cells in vitro and in vivo.
Topics: A549 Cells; Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Biphenyl Compounds; Cell Line, Tumor; Cell Survival; Dose-Response Relationship, Drug; Drug Synergism; Female; Humans; Lung Neoplasms; Mice; Mice, Nude; Nitrophenols; Phosphorylcholine; Piperazines; Sulfonamides; Treatment Outcome | 2016 |
Synergistic cytotoxicity of perifosine and ABT-737 to colon cancer cells.
Topics: Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Colonic Neoplasms; Drug Synergism; Humans; Phosphatidylinositol 3-Kinases; Phosphorylcholine; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Tumor Microenvironment | 2023 |