Compounds > perifosine
Page last updated: 2024-09-04

perifosine and 2-(4-morpholinyl)-8-phenyl-4h-1-benzopyran-4-one

perifosine has been researched along with 2-(4-morpholinyl)-8-phenyl-4h-1-benzopyran-4-one in 2 studies

Compound Research Comparison

Studies
(perifosine)		Trials
(perifosine)		Recent Studies (post-2010)
(perifosine)		Studies
(2-(4-morpholinyl)-8-phenyl-4h-1-benzopyran-4-one)		Trials
(2-(4-morpholinyl)-8-phenyl-4h-1-benzopyran-4-one)		Recent Studies (post-2010) (2-(4-morpholinyl)-8-phenyl-4h-1-benzopyran-4-one)
245311404,82351,810

Protein Interaction Comparison

ProteinTaxonomyperifosine (IC50)2-(4-morpholinyl)-8-phenyl-4h-1-benzopyran-4-one (IC50)
Chain A, Proto-oncogene serine/threonine-protein kinase Pim-1Homo sapiens (human)4
Chain A, Proto-oncogene serine/threonine-protein kinase Pim-1Homo sapiens (human)4
Chain A, Methyltransferase WbddEscherichia coli68
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoformHomo sapiens (human)1.6413
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit betaHomo sapiens (human)1.4218
5-hydroxytryptamine receptor 4Cavia porcellus (domestic guinea pig)1.002
cGMP-specific 3',5'-cyclic phosphodiesteraseHomo sapiens (human)9.614
Cytochrome P450 1A2Homo sapiens (human)1
Neuronal acetylcholine receptor subunit alpha-4Rattus norvegicus (Norway rat)1.6
Serine/threonine-protein kinase pim-1Homo sapiens (human)3.364
Neuronal acetylcholine receptor subunit beta-2Rattus norvegicus (Norway rat)1.6
Casein kinase II subunit alpha'Homo sapiens (human)6.9
Phosphatidylinositol 3-kinase regulatory subunit alphaHomo sapiens (human)3.1638
5-hydroxytryptamine receptor 2AHomo sapiens (human)2.796
5-hydroxytryptamine receptor 2CHomo sapiens (human)1.002
Sodium-dependent serotonin transporterRattus norvegicus (Norway rat)2.3
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoformBos taurus (cattle)3.7533
Type-1 angiotensin II receptorOryctolagus cuniculus (rabbit)0.5
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoformHomo sapiens (human)1.4593
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Mus musculus (house mouse)0.5
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoformHomo sapiens (human)1.2922
Serine/threonine-protein kinase mTORHomo sapiens (human)4.1638
Serine/threonine-protein kinase mTORRattus norvegicus (Norway rat)2.5
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform Homo sapiens (human)2.4845
Glycogen synthase kinase-3 betaHomo sapiens (human)8.1
Serine/threonine-protein kinase PLK1Homo sapiens (human)2.05
Casein kinase II subunit betaHomo sapiens (human)6.9
Casein kinase II subunit alphaHomo sapiens (human)6.9
DNA-dependent protein kinase catalytic subunitHomo sapiens (human)1.32
Mu-type opioid receptorCavia porcellus (domestic guinea pig)1.6
Serine/threonine-protein kinase pim-3Homo sapiens (human)1.4
Phosphoinositide 3-kinase regulatory subunit 5Homo sapiens (human)1.72
Serine/threonine-protein kinase PLK3Homo sapiens (human)3

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (50.00)29.6817
2010's1 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bologna, M; Dolo, V; Festuccia, C; Gravina, GL; Millimaggi, D; Muzi, P; Vicentini, C1
Chen, F; Ji, F; Liu, W; Mao, L; Wang, S; Xie, Y1

Other Studies

2 other study(ies) available for perifosine and 2-(4-morpholinyl)-8-phenyl-4h-1-benzopyran-4-one

ArticleYear
Akt down-modulation induces apoptosis of human prostate cancer cells and synergizes with EGFR tyrosine kinase inhibitors.
    The Prostate, 2008, Jun-15, Volume: 68, Issue:9

    Topics: Apoptosis; Blotting, Western; Caspases; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Chromones; Drug Synergism; Enzyme Activation; Epidermal Growth Factor; Erlotinib Hydrochloride; Flow Cytometry; Humans; Male; Morpholines; Neoplasms, Hormone-Dependent; Phosphorylcholine; Prostatic Neoplasms; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; PTEN Phosphohydrolase; Quinazolines

2008
Icariside II activates EGFR-Akt-Nrf2 signaling and protects osteoblasts from dexamethasone.
    Oncotarget, 2017, Jan-10, Volume: 8, Issue:2

    Topics: Animals; Cell Line; Cell Proliferation; Cell Survival; Chromones; Dexamethasone; ErbB Receptors; Flavonoids; Heterocyclic Compounds, 3-Ring; Mice; Morpholines; NF-E2-Related Factor 2; Osteoblasts; Phosphorylcholine; Proto-Oncogene Proteins c-akt; Reactive Oxygen Species; Signal Transduction

2017