Compounds > perhydrohistrionicotoxin
Page last updated: 2024-09-02

perhydrohistrionicotoxin and phencyclidine

perhydrohistrionicotoxin has been researched along with phencyclidine in 8 studies

Compound Research Comparison

Studies
(perhydrohistrionicotoxin)		Trials
(perhydrohistrionicotoxin)		Recent Studies (post-2010)
(perhydrohistrionicotoxin)		Studies
(phencyclidine)		Trials
(phencyclidine)		Recent Studies (post-2010) (phencyclidine)
460128,2943877,796

Protein Interaction Comparison

ProteinTaxonomyperhydrohistrionicotoxin (IC50)phencyclidine (IC50)
Glutamate receptor ionotropic, NMDA 1 Rattus norvegicus (Norway rat)0.1299
Lysosomal Pro-X carboxypeptidaseHomo sapiens (human)0.091
Glutamate receptor ionotropic, NMDA 2A Rattus norvegicus (Norway rat)0.1299
Glutamate receptor ionotropic, NMDA 2BRattus norvegicus (Norway rat)0.1299
Glutamate receptor ionotropic, NMDA 2CRattus norvegicus (Norway rat)0.1299
Glutamate receptor ionotropic, NMDA 1Homo sapiens (human)0.5563
Glutamate receptor ionotropic, NMDA 2AHomo sapiens (human)0.205
Glutamate receptor ionotropic, NMDA 2BHomo sapiens (human)1.2589
Glutamate receptor ionotropic, NMDA 2DRattus norvegicus (Norway rat)0.1299
Glutamate receptor ionotropic, NMDA 3BRattus norvegicus (Norway rat)0.1299
Sigma non-opioid intracellular receptor 1Rattus norvegicus (Norway rat)0.53
Glutamate receptor ionotropic, NMDA 3ARattus norvegicus (Norway rat)0.1299

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19908 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Albuquerque, EX; Aronstam, RS; Daly, JW; Feigl, DM; King, CT1
Aguayo, LG; Albuquerque, EX; Witkop, B1
Aronstam, RS; Hong, JS1
Albuquerque, EX; Aronstam, RS; Eldefrawi, AT; Eldefrawi, ME; Tsai, MC1
Aronstam, RS1
Abbassy, MA; Ei-Fakahany, EF; Eldefrawi, AT; Eldefrawi, ME; Miller, ER1
Aronstam, RS; King, CT1
Changeux, JP; Heidmann, T; Oswald, RE1

Other Studies

8 other study(ies) available for perhydrohistrionicotoxin and phencyclidine

ArticleYear
Binding of [3H]perhydrohistrionicotoxin and [3H]phencyclidine to the nicotinic receptor-ion channel complex of Torpedo electroplax. Inhibition by histrionicotoxins and derivatives.
    Biochemical pharmacology, 1985, Sep-01, Volume: 34, Issue:17

    Topics: Amphibian Venoms; Animals; Binding, Competitive; Carbachol; Chemical Phenomena; Chemistry; Electric Organ; In Vitro Techniques; Ion Channels; Phencyclidine; Receptors, Nicotinic; Structure-Activity Relationship; Torpedo

1985
Voltage- and time-dependent effects of phencyclidines on the endplate current arise from open and closed channel blockade.
    Proceedings of the National Academy of Sciences of the United States of America, 1986, Volume: 83, Issue:10

    Topics: Acetylcholine; Amphibian Venoms; Animals; Cells, Cultured; Electric Conductivity; In Vitro Techniques; Ion Channels; Membrane Potentials; Motor Endplate; Muscle Denervation; Neuromuscular Junction; Phencyclidine; Rana pipiens; Rats; Time Factors

1986
Interactions of chlordecone (kepone) and mirex with the nicotinic acetylcholine receptor--ion channel complex.
    Toxicology letters, 1986, Volume: 30, Issue:3

    Topics: Allosteric Regulation; Amphibian Venoms; Animals; Bungarotoxins; Carbachol; Chlordecone; Electric Organ; In Vitro Techniques; Insecticides; Ion Channels; Mirex; Phencyclidine; Receptors, Nicotinic; Torpedo

1986
Sites of action of phencyclidine. II. Interaction with the ionic channel of the nicotinic receptor.
    Molecular pharmacology, 1980, Volume: 18, Issue:2

    Topics: Acetylcholine; Amphibian Venoms; Animals; Electric Organ; Electrophysiology; Fishes; In Vitro Techniques; Ion Channels; Muscle Contraction; Phencyclidine; Rana pipiens; Rats; Receptors, Cholinergic; Receptors, Nicotinic

1980
Interactions of tricyclic antidepressants with a synaptic ion channel.
    Life sciences, 1981, Jan-05, Volume: 28, Issue:1

    Topics: Acetylcholine; Amitriptyline; Amphibian Venoms; Animals; Antidepressive Agents, Tricyclic; Binding Sites; Desipramine; Electric Organ; Fishes; Imipramine; Ion Channels; Nortriptyline; Phencyclidine; Receptors, Nicotinic

1981
Alcohol modulation of drug binding to the channel sites of the nicotinic acetylcholine receptor.
    The Journal of pharmacology and experimental therapeutics, 1983, Volume: 224, Issue:2

    Topics: Alcohols; Amphibian Venoms; Animals; Carbachol; Drug Interactions; Imipramine; Ion Channels; Membranes; Naphthols; Phencyclidine; Receptors, Cholinergic; Torpedo

1983
Benzomorphan interactions with acetylcholine receptor complexes from Torpedo.
    European journal of pharmacology, 1983, Jun-17, Volume: 90, Issue:4

    Topics: Amphibian Venoms; Animals; Benzomorphans; Drug Interactions; Ion Channels; Morphinans; Parasympatholytics; Phencyclidine; Receptors, Cholinergic; Receptors, Nicotinic; Receptors, Opioid; Torpedo

1983
Multiple sites of action for noncompetitive blockers on acetylcholine receptor rich membrane fragments from torpedo marmorata.
    Biochemistry, 1983, Jun-21, Volume: 22, Issue:13

    Topics: Alkanes; Allosteric Regulation; Amphibian Venoms; Animals; Binding Sites; Chlorpromazine; Electric Organ; Isoquinolines; Membrane Lipids; Neuromuscular Junction; Parasympatholytics; Phencyclidine; Polyethylene Glycols; Proadifen; Receptors, Cholinergic; Torpedo

1983