perhexiline and trimetazidine

perhexiline has been researched along with trimetazidine in 16 studies

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (12.50)18.2507
2000's9 (56.25)29.6817
2010's5 (31.25)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Arduini, A; Ceccarelli, SM; Chomienne, O; Gubler, M1
Chirkov, YY; Chirkova, LP; Horowitz, JD; Kennedy, JA; Murphy, GA; Willoughby, SR1
Horowitz, JD; Kennedy, JA1
Frenneaux, M; Horowitz, J; Lee, L1
Inglis, S; Stewart, S1
Abozguia, K; Clarke, K; Frenneaux, M; Lee, L1
Celik, T; Iyisoy, A; Jata, B; Kursaklioglu, H1
Marazzi, G; Rosano, GM; Volterrani, M1
Ashrafian, H; Frenneaux, MP; Williams, L1
Arora, R; Jawad, E1
Arioli, F; Bassanelli, G; Fragasso, G; Margonato, A; Salerno, A; Spoladore, R1
Di Napoli, P1
Mellana, WM; Mohan, D; Palaniswamy, C; Selvaraj, DR1
Chirkov, YY; Horowitz, JD; Kennedy, JA; Sverdlov, AL1
Amaral, N; Okonko, DO1
Heggermont, WA; Heymans, S; Papageorgiou, AP; van Bilsen, M1

Reviews

9 review(s) available for perhexiline and trimetazidine

ArticleYear
Metabolic manipulation in ischaemic heart disease, a novel approach to treatment.
    European heart journal, 2004, Volume: 25, Issue:8

    Topics: Acetanilides; Adrenergic beta-Antagonists; Angina Pectoris; Cardiovascular Agents; Drug Therapy, Combination; Enzyme Inhibitors; Epoxy Compounds; Glucose; Humans; Hypoglycemic Agents; Insulin; Myocardial Ischemia; Myocardium; Perhexiline; Piperazines; Potassium; Ranolazine; Trimetazidine

2004
Metabolic therapeutics in angina pectoris: history revisited with perhexiline.
    European journal of cardiovascular nursing, 2006, Volume: 5, Issue:2

    Topics: Acetanilides; Angina Pectoris; Calcium Channel Blockers; Cardiovascular Agents; Carnitine O-Palmitoyltransferase; Drug Monitoring; Epoxy Compounds; Fatty Acids; Half-Life; Humans; Metabolic Clearance Rate; Nurse's Role; Nursing Assessment; Patient Education as Topic; Patient Selection; Perhexiline; Piperazines; Randomized Controlled Trials as Topic; Ranolazine; Treatment Outcome; Trimetazidine; Vasodilator Agents

2006
Modification of myocardial substrate use as a therapy for heart failure.
    Nature clinical practice. Cardiovascular medicine, 2006, Volume: 3, Issue:9

    Topics: Acetanilides; Adrenergic beta-Antagonists; Animals; Cardiac Output, Low; Cardiovascular Agents; Energy Metabolism; Epoxy Compounds; Fatty Acids, Nonesterified; Glycine; Heart; Humans; Myocardium; Oxygen; Perhexiline; Piperazines; Ranolazine; Trimetazidine

2006
Chronic stable angina pectoris.
    Disease-a-month : DM, 2008, Volume: 54, Issue:9

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Acetanilides; Angina Pectoris; Antihypertensive Agents; Benzazepines; Bosentan; Chronic Disease; Counterpulsation; Cyclic Nucleotide-Gated Cation Channels; Exercise Test; Heart Murmurs; Humans; Ivabradine; Myocardial Contraction; Myocardial Ischemia; Myocardial Revascularization; Myocardium; Nicorandil; Oxygen Consumption; Perhexiline; Piperazines; Protein Kinase Inhibitors; Ranolazine; Sulfonamides; Trimetazidine; Vasodilator Agents

2008
Metabolic therapy of heart failure.
    Current pharmaceutical design, 2008, Volume: 14, Issue:25

    Topics: Animals; Cardiovascular Agents; Carnitine O-Palmitoyltransferase; Fatty Acids, Nonesterified; Heart Failure; Humans; Myocardium; Perhexiline; Trimetazidine

2008
Metabolic modulation: a new therapeutic target in treatment of heart failure.
    American journal of therapeutics, 2011, Volume: 18, Issue:6

    Topics: Acetanilides; Carnitine O-Palmitoyltransferase; Enzyme Inhibitors; Epoxy Compounds; Fatty Acids; Glucose; Heart Failure; Humans; Mitochondria, Heart; Myocytes, Cardiac; Perhexiline; Piperazines; Ranolazine; Trimetazidine; Vasodilator Agents

2011
Modulation of myocardial metabolism: an emerging therapeutic principle.
    Current opinion in cardiology, 2010, Volume: 25, Issue:4

    Topics: Acetanilides; Amiodarone; Cardiovascular Agents; Heart Failure; Humans; Hypertrophy, Left Ventricular; Myocardial Ischemia; Myocardial Perfusion Imaging; Myocardial Reperfusion; Myocardium; Perhexiline; Piperazines; Ranolazine; Trimetazidine; Vasodilator Agents

2010
Metabolic abnormalities of the heart in type II diabetes.
    Diabetes & vascular disease research, 2015, Volume: 12, Issue:4

    Topics: Antioxidants; Cardiovascular Agents; Diabetes Mellitus, Type 2; Diabetic Cardiomyopathies; Energy Metabolism; Fatty Acids; Glucose; Humans; Mitochondria, Heart; Myocardium; Organophosphorus Compounds; Oxidative Phosphorylation; Oxidative Stress; Perhexiline; Ranolazine; Trimetazidine; Ubiquinone

2015
Metabolic support for the heart: complementary therapy for heart failure?
    European journal of heart failure, 2016, Volume: 18, Issue:12

    Topics: Acetyl-CoA C-Acyltransferase; Cardiovascular Agents; Carnitine; Carnitine O-Palmitoyltransferase; Dichloroacetic Acid; Energy Metabolism; Enzyme Inhibitors; Epoxy Compounds; Fatty Acids; Glucose; Heart Failure; Humans; Myocardium; Myocytes, Cardiac; Oxidation-Reduction; Perhexiline; Ranolazine; Stroke Volume; Trimetazidine

2016

Other Studies

7 other study(ies) available for perhexiline and trimetazidine

ArticleYear
Carnitine palmitoyltransferase (CPT) modulators: a medicinal chemistry perspective on 35 years of research.
    Journal of medicinal chemistry, 2011, May-12, Volume: 54, Issue:9

    Topics: Animals; Carnitine; Carnitine O-Palmitoyltransferase; Catalytic Domain; Diabetes Mellitus, Type 2; Energy Metabolism; Enzyme Activators; Ethylene Oxide; Heart Failure; Humans; Insulin Resistance; Isoenzymes; Lipid Metabolism; Myocardial Ischemia; Organ Specificity; Protein Conformation; Sequence Homology, Amino Acid; Stereoisomerism

2011
Inhibition of long-chain fatty acid metabolism does not affect platelet aggregation responses.
    European journal of pharmacology, 1998, Sep-04, Volume: 356, Issue:2-3

    Topics: Adult; Aged; Amiodarone; Blood Platelets; Cardiovascular Agents; Carnitine O-Palmitoyltransferase; Case-Control Studies; Enzyme Inhibitors; Epoxy Compounds; Fatty Acids; Female; Humans; Male; Middle Aged; Perhexiline; Platelet Aggregation; Trimetazidine; Vasodilator Agents

1998
Effect of trimetazidine on carnitine palmitoyltransferase-1 in the rat heart.
    Cardiovascular drugs and therapy, 1998, Volume: 12, Issue:4

    Topics: Amiodarone; Animals; Carnitine O-Palmitoyltransferase; Dose-Response Relationship, Drug; In Vitro Techniques; Male; Mitochondria, Heart; Myocardial Ischemia; Myocardium; Perhexiline; Rats; Rats, Sprague-Dawley; Trimetazidine

1998
Metabolic agents in the management of diabetic coronary patients: a new era.
    International journal of cardiology, 2008, Jun-23, Volume: 127, Issue:1

    Topics: Carnitine; Coronary Disease; Diabetes Mellitus; Diabetic Angiopathies; Dichloroacetic Acid; Enzyme Inhibitors; Epoxy Compounds; Humans; Perhexiline; Trimetazidine; Vasodilator Agents; Vitamin B Complex

2008
Metabolic agents in the management of diabetic coronary patients: a new era.
    International journal of cardiology, 2008, Jun-23, Volume: 127, Issue:1

    Topics: Acetanilides; Citric Acid Cycle; Coronary Disease; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Dichloroacetic Acid; Enzyme Inhibitors; Epoxy Compounds; Humans; Insulin Resistance; Perhexiline; Piperazines; Ranolazine; Trimetazidine; Vasodilator Agents

2008
The pathophysiology of heart failure: a tale of two old paradigms revisited.
    Clinical medicine (London, England), 2008, Volume: 8, Issue:2

    Topics: Cardiovascular Agents; Cardiovascular Physiological Phenomena; Clinical Trials as Topic; Heart Failure; Humans; Metabolic Networks and Pathways; Perhexiline; Trimetazidine; Vasodilator Agents

2008
The metabolic treatment of coronary artery disease and heart failure.
    Current pharmaceutical design, 2009, Volume: 15, Issue:8

    Topics: Carnitine O-Palmitoyltransferase; Coronary Artery Disease; Epoxy Compounds; Heart Failure; Humans; Perhexiline; Trimetazidine; Vasodilator Agents

2009