perhexiline has been researched along with piperidines in 233 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 232 (99.57) | 18.7374 |
1990's | 1 (0.43) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Becq-Giraudon, B; Boutaud, PH; Demange, J; Pouget-Abadie, JF; Sudre, Y | 1 |
Cho, YW; Ito, H; Matsukawa, H; Okabe, E; Sakamoto, H | 1 |
Wallace, DC | 2 |
Gitlin, N | 3 |
Acar, J; Luxereau, PH | 1 |
de Saint-Maur, PP; Lageron, A; Lévy, VG; Poupon, R | 1 |
Kopelman, P; Morgan, PG | 1 |
McDonald, GS | 2 |
Baumann, N; Escourolle, R; Hauw, JJ; Pollet, S | 1 |
Corriat, A; Houdent, CE; Wolf, LM | 1 |
Goulding, L; Pickering, TG | 1 |
Sebille, A | 2 |
Dawkins, KD; O'Connor, E | 1 |
Raabe, DS | 1 |
Boutry, JM; Escourolle, R; Hamam, S; Hauw, JJ | 1 |
Gaillard de Collogny, L; Gras, HJ; Theron, H | 1 |
Bourrat, C; Guastala, JP; Viala, JJ | 1 |
Chedru, F; Fardeau, M; Lhermitte, F; Mallecourt, J | 1 |
Becq-Giraudon, B; Gil, R; Marin, J; Pouget-Abadie, JF; Sudre, Y | 1 |
Escourolle, R; Hauw, JJ; Mussini, JM | 1 |
Campbell, IW; Fraser, DM; Miller, HC | 1 |
Blanc, JJ; Mabin, D; Penther, P | 1 |
Bouche, P; Bousser, MG; Hauw, JJ; Laplane, D; Singlas, E; Touboul, PJ | 1 |
Martin, HJ; Masingue, M; Petit, H; Pruvot, J | 1 |
Mashaly, R; Poisson, M; Sichez, JP; Tempier, P | 1 |
Cuny, G; Floquet, A; Grignon, G; Penin, F; Serot, JM | 1 |
Haut, J; Poisson, M; Schaison, M; Sichez, JP; van Effenterre, G; van Effenterre, R | 1 |
Fraser, DM; Miller, HC | 1 |
Lüllmann, H; Lüllmann-Rauch, R | 1 |
de Saint-Maur, PP; Hauw, JJ; Lageron, A; Lecomte, D; Pollet, S; Poupon, R; Singer, B | 1 |
Said, G | 1 |
Jung, HJ; Suzuki, K | 1 |
Bakouche, P; Baumann, N; Dudognon, P; Ermidou, S; Escourolle, R; Hauw, JJ; Lévy, J; Nick, J; Nicolle, MH; Pollet, S; Reignier, A; Singlas, E | 1 |
Benhamou, JP; Bichara, M; Degott, C; Feldmann, G; Pessayre, D; Potet, F | 1 |
Jallon, P; Loiseau, P; Orgogozo, JM; Singlas, E | 1 |
Baumann, N; Escourolle, R; Hauw, JJ; Le Saux, F; Pollet, S; Turpin, JC | 1 |
Bouche, P; Bousser, MG; Cathala, HP; Peytour, MA | 1 |
Jung, HJ; Suzuki, K; Weisenfreund, J; Willson, NJ | 1 |
Bady, B; Bourrat, C; Carrier, H; Girard, PF; Trillet, M | 1 |
Stenbäck, U | 1 |
Colen, A; Dernier, J | 1 |
Baron, DK; Ghods, A | 1 |
Myburgh, DP | 1 |
Day, LJ; Sowton, E | 1 |
Pilcher, J | 2 |
Baldet, P; Bertrand, L; Blanc, F; Puyeo, J | 1 |
Arroyo, JB; Batlouni, M; Besen, D; Bozza, A; de Brito, FS; de Britto, AH; Di Piero, EF; Dohmann, H; Duprat, R; Federico, W; Ferreira, FM; Gomes, FJ; Malagrino, A; Nogueira, A; Santos, DV; Studart, PC; Wagner, M | 1 |
de Brito, FS; Pereira, MH | 1 |
Dando, RV; Eathorne, AJ; Hitchcock, PJ; Rutovitz, IJ; Weiss, G | 1 |
Isaacson, C; Kew, MC; Lewis, D; Wainwright, HC; Zwi, S | 1 |
Daniell, HB; Saelens, DA; Webb, JG | 1 |
Affaki, GS; Bonan, R; Crittin, J; Mizgala, HF; Théroux, P; Waters, DD | 1 |
Horowitz, JD; Mashford, ML | 2 |
Faure, H; Fournet, J; Massot, C; Meullenet, J; Roche, J | 1 |
Fondacaro, JD; Jacobson, ED; Schwaiger, M | 1 |
Hoenig, V; Werner, F | 4 |
Mikol, J | 1 |
Beaugrand, M; Callard, P; Lageron, A | 1 |
Lageron, A | 1 |
Forbes, GB; Rake, MO; Taylor, DJ | 1 |
Ferlemann, HJ; Kaltenbach, M; Krehan, L | 1 |
Bregetzer, J | 1 |
Stentiford, NH | 1 |
Beaugrand, M; Callard, P; Camilleri, JP; Chousterman, M; Ferrier, JP; Petite, J | 1 |
Eddy, JD; Parsons, LM; Singh, SP; Stephens, WP | 2 |
Gawler, J; Hutchinson, WM; Williams, J | 1 |
Assan, R; Cousteau, JP; Singlas, E | 1 |
Adamska-Dyniewska, H; Dziekański, S | 1 |
Bournerias, F; Goulon, M; Margent, P | 1 |
Goujet, MA; Simon, P; Singlas, E | 2 |
Bertrand, A; Bonnet, P; Janbon, F; Jourdan, J; Michel, H | 1 |
Candau, LA; de Patta, M; Padilha, JC; Scherr, C; Tasca, R; Weiskopf, JS | 1 |
Belhadjali, J; Berger, F; Fournier, G; Paliard, P; Patricot, L; Vitrey, D | 1 |
Beaugrand, M; Callard, P; Darnis, F; Ferrier, JP; Lageron, A; Lecomte, D; Lévy, VG; Poupon, R | 1 |
Boucher, M; Duchene-Marullaz, D | 1 |
Glogar, D; Linkesch, W; Niederberger, M | 1 |
Bassan, M; Shalev, O | 1 |
Myers, JB; Ronthal, M | 1 |
Macnair, DR; Murray, W; Talbot, MD | 1 |
Detilleux, JM; Rausin, G | 1 |
Albanese, MC; Feruglio, GA | 1 |
Dalla Volta, S; Episcopo, U; Gemelli, A; Permutti, B | 1 |
del Guercio, R | 1 |
Lockhart, JD; Masheter, HC | 2 |
Caponnetto, S; Iannetti, M; Masperone, MA; Pastorini, C; Perugini, P | 1 |
Forattini, C; Perin, S | 1 |
Arroyo, JB; Bozza, A; Brito, FS; Britto, AH; Dohmann, HF; Gomes, FJ; Laffront, G; Nogueira, A; Piero, EF; Santos, DV | 1 |
Masoni, A; Oriani, GA; Tomasi, AM | 1 |
Brown, MJ; Horowitz, JD; Mashford, ML | 1 |
Conradi, SE; Daniell, HB; Gaffney, TE; Privitera, PJ | 1 |
Epstein, H | 1 |
Arnott, G; Berenchtein-Fortier, S; Boulenge-Beaussart, L; Hache, JC; Masingue, M; Michaux, F | 1 |
Rosenthal, FD; Tomlinson, IW | 1 |
Assan, R; Dally, S; Gaultier, M; Lagier, G | 1 |
Caponnetto, S; Iannetti, M; Masperone, MA; Oriani, G; Pastorini, C; Perugini, P | 1 |
Alberizio, A; Castellaneta, G; Cristallo, E; Losignore, M; Palma, B | 1 |
Albanese, P; Cristallo, E; De Luca, I; Fino, E; Mitolo, E; Palma, B | 1 |
de Saint-Maur, PP; Lageron, A; Lecomte, D; Lévy, VG | 1 |
Adamska-Dyniewska, H; Atta, W; Bala, T; Dziekański, S | 1 |
Lee, RJ | 1 |
Chagnon, A; Herne, N; Le Gall, F; Marion, J; Raillat, A | 1 |
Gaudy, M; Gaudy, MC | 1 |
Campello, AP; Klüppel, ML; Lopes, LC; Silveira, O | 1 |
Bickert, P; Rullière, R | 1 |
Bhagat, SJ; Bhootra, RK; Datey, KK; Goyal, BK; Iyer, RS; Mishra, SJ; Rajalaxmi, BN; Surana, MC | 1 |
Garten, J; Werhrschütz, E | 1 |
Cunha, GP; Lopes, M; Maranhão, MF; Oliveira, PF; Rojas, RI | 1 |
Correale, E; Corsini, G; Oriani, G; Persico, S; Tritto, C | 1 |
Grand, A; Sepulchre, P | 2 |
Roche, P | 1 |
Gray, DR; Harter, KW; Janzen, DA; Mason, DT; Massumi, RA; Vera, Z | 1 |
Doumax, Y; Manciet, G; Nogue, F; Ragnaud, JM; Roger, P | 1 |
Casanova, R; Cornacchia, D; Finzi, C; Fischer, DM; Jacopi, F | 1 |
Circo, A; Galassi, A; Mangiameli, S | 1 |
Corsini, B; Di Muzio, M; Gatto, E | 1 |
Bouche, P; Bousser, MG; Brochard, C; Herreman, G | 1 |
Bory, R; Lambert, R; Paliard, P; Pelletier, M | 1 |
Klassen, GA; L'Abbate, A; Mildenberger, RR; Sestier, F; Zborowska-Sluis, DT | 1 |
Bellotti, G; Décourt, LV; Pilegi, F | 1 |
Alcocer, L; Arce-Gomez, E; Aspe, J | 2 |
Carre, A; Ketelers, JY; Warembourg, H | 1 |
Dettori, AG; Fatti, F; Malagnino, G; Oriani, G | 1 |
Hudak, WJ; Kuhn, WL; Lewis, RE; Lucas, RW | 1 |
Gomez, EA; Hamdan, G; Ramirez, MA; Vargas, G | 1 |
Bemiller, CR; Pepne, CJ; Schang, SJ | 1 |
Gras, H; Marcheix, JC; Ponsonnaille, J; Theron, M | 1 |
Fleury, G; Massabie, R | 1 |
Dalvi, CP; Datey, KK | 1 |
Morgans, CM; Rees, JR | 1 |
Gitlin, N; Nellen, M | 1 |
Antonioli, G; Concina, B; Gregorini, L; Libertti, A; Marini, O; Masoni, A; Tomasi, AM; Valentini, R | 1 |
Armstrong, ML | 1 |
Boyce, MJ; Chandrasekhar, KP; Ikram, H; Peirce, TH; Pilcher, J; Rees, JR | 1 |
Cawein, MJ; Hoekenga, MT; Hudak, WJ; Lewis, RE | 1 |
Newberne, JW | 1 |
Bemiller, CR; Pepine, CJ; Schang, SJ | 2 |
Sukerman, M | 1 |
Dirnberger, G; Drake, FT; Haring, O; Singer, DH | 1 |
Morledge, J | 1 |
Bina, M; Cherchi, A; Fonzo, R; Raffo, M | 1 |
Amin, BM; Bagri, AK; Bhootra, RK; Datey, KK; Kelkar, PN; Varma, SR | 1 |
Chaves, JL; Loyola, SF; Martins de Oliveira, J | 1 |
Garson, WP; Gülin, RC; Phear, DN | 1 |
Luccioni, R; Trigano, JA | 1 |
Burns-Cox, CJ; Chandrasekhar, KP; Ikram, H; Peirce, TH; Pilcher, J; Quinlan, CD; Rees, JR | 1 |
Bunde, CA; Cawein, MJ; Griffin, CL; Hoekenga, MT; Kuzma, RJ | 1 |
Kucuruza, I | 1 |
Rees, JR | 2 |
Souza, AD | 1 |
Cunha, GP; Lopes, M; Maranhão, MF; Rojas, R | 1 |
Binet, P; Henin, JM; Raynaud, P; Raynaud, R | 1 |
Bhootra, RK; Dalvi, CP; Datey, KK; Kelkar, PN | 1 |
Barraine, R; Demange, J; Marin, J | 1 |
Fayard, JM; Gay, J; Maurice, P; Ourbak, P; Queste, M | 1 |
Clark, ML; Czerwinski, AB; Czerwinski, AW; Whitsett, TL | 1 |
Singer, DH; Ten Eick, RE | 1 |
Lang, JF; Leeson, GA; Wright, GJ; Zeiger, AV | 1 |
Abaza, A; Aziza, C; Cattan, D; Pappo, E | 1 |
Pepine, CJ | 1 |
Gerbaux, A; Hiltgen, M; Steff, PH | 1 |
Perrin, A; Saint-Pierre, A | 1 |
Opie, LH | 1 |
Cooper, JD; Turnell, DC | 1 |
Albouz, S; Baudrimont, M; Baumann, N; Boutry, JM; Escourolle, R; Harpin, ML; Hauw, JJ | 1 |
Cho, YW; Fujisawa, T; Higashi, H; Ito, H; Okabe, E | 1 |
Carabott, F; Heathfield, KW | 1 |
Dawes, P; Moulder, C | 1 |
Decker, N; Leclerc, G; Schwartz, J | 1 |
Lowe, JB; White, HD | 1 |
Critchley, EM; Fahim, Y; Lynch, PG; Wijesekera, JC; Wright, JS | 1 |
Gordon, AS; Gordon, M | 1 |
Gautier, M; Lageron, A; Scotto, J | 1 |
Idle, JR; Lockhart, JD; Oates, NS; Shah, RR; Smith, RL | 2 |
Albouz, S; Baumann, N; Boutry, JM; Escourolle, R; Harpin, ML; Hauw, JJ; Mussini, JM; Pollet, S | 1 |
Albouz, S; Bajolet, A; Baumann, N; Caulet, T; Pluot, M; Turpin, JC | 1 |
Gwynne, JF; Hay, DR | 1 |
Robson, RA; Wing, LM | 1 |
Albert, C; Lüllmann-Rauch, R | 1 |
Oguro, K; Ono, H | 1 |
Coulter, DM | 1 |
Hashimoto, K; Ohara, N; Ono, H | 1 |
Malicier, D; Rouzioux, JM | 1 |
Grgurinovich, N | 1 |
Dunn, D; Pieterse, AS; Rowland, R | 1 |
Ikram, H; Maslowski, AH | 1 |
Cheucle-Beaughard, M; Duchene-Marullaz, P; Michelin, MT | 1 |
Antman, EM; Braunwald, E; Muller, JE; Stone, PH | 1 |
Evreux, JC; Léry, N; Paliard, P | 1 |
Anderes, U; Burkart, F; Dieterich, HA; Follath, F | 1 |
Goble, AJ; Horowitz, JD; White, HD | 1 |
Colman, J; Mandelcorn, M; Murphy, J | 1 |
Bendirdjian, JP; Bichara, M; Fillastre, JP; Foucher, B; Viotte, G | 1 |
Bourel, M; Deugnier, Y; Glaise, D; Guillouzo, A; Le Gall, JY; Messner, M | 1 |
Boucard, M; François, C; Michel, H; Sablier, G; Sentein, P; Vic, P | 1 |
Frisch, W; Lüllmann-Rauch, R | 2 |
Bergey, JL; McCallum, JD; Nocella, K | 1 |
Drummer, OH; Goble, AJ; Horowitz, JD; Louis, WJ; Morris, PM | 1 |
Albouz, S; Baumann, N; Bourdon, R; Boutry, JM; Dubois, G; Hauw, JJ | 1 |
Basu, AK; Gupta, MP; Kaur, AH; Seth, SD | 1 |
Colebunders, R; Ranquin, R | 1 |
Cohn, D; Petroff, V; Roberts, RK; Seneviratne, B | 1 |
Hashimoto, K; O'Hara, N; Ono, H | 1 |
Weisser, P; Wink, K | 1 |
Fuentes, C; Marty, R; Marty-Double, C; Pagès, AM; Pagès, M | 1 |
Darnis, F; Gombeau, T; Lageron, A; Poupon, R; Prudhomme de Saint-Maur, P; Rosensztajn, L | 1 |
Atkinson, AB; McAreavey, D; Trope, G | 1 |
Caruzzo, C; Cremo, R; Troni, W | 1 |
Klassen, GA; Wright, GJ; Zborowska-Sluis, DT | 1 |
Fitzgerald, O; Long, JP; Maurer, BJ | 1 |
Breit, SN; Bursill, JA; Campbell, TJ; Qiu, MR; Singleton, CB; Tie, H; Valenzuela, SM; Walker, BD; Wyse, KR | 1 |
4 review(s) available for perhexiline and piperidines
Article | Year |
---|---|
[Toxic neurologic manifestations during angina pectoris treatment (perhexiline maleate and amiotadone hydrochloride)].
Topics: Amiodarone; Angina Pectoris; Benzofurans; Cerebrospinal Fluid Proteins; Electromyography; Humans; Inclusion Bodies; Lipid Metabolism; Microscopy, Electron; Movement Disorders; Muscles; Nervous System Diseases; Paresthesia; Perhexiline; Peripheral Nerves; Peripheral Nervous System Diseases; Pigments, Biological; Piperidines; Polyradiculoneuropathy; Schwann Cells; Skin; Tremor | 1978 |
[Cirrhogenic hepatitis due to perhexiline maleate: general review based upon one new case with ultrastructural study (author's transl)].
Topics: Aged; Angina Pectoris; Chemical and Drug Induced Liver Injury; Diagnosis, Differential; Female; Hepatitis, Alcoholic; Humans; Liver; Liver Cirrhosis; Perhexiline; Piperidines | 1978 |
[Proceedings: Review of the cardiovascular pharmacology of perhexiline].
Topics: Animals; Anti-Arrhythmia Agents; Blood Pressure; Blood Vessels; Cardiac Output; Diuresis; Dogs; Energy Metabolism; Guinea Pigs; Heart; Heart Atria; Heart Conduction System; Heart Rate; Heart Ventricles; Hemodynamics; Humans; In Vitro Techniques; Myocardium; Nitroglycerin; Oxygen Consumption; Perhexiline; Piperidines; Rabbits; Rats; Receptors, Cholinergic; Vasodilator Agents | 1973 |
Calcium channel blocking agents in the treatment of cardiovascular disorders. Part II: Hemodynamic effects and clinical applications.
Topics: Benzazepines; Calcium Channel Blockers; Cardiovascular Diseases; Coronary Circulation; Diltiazem; Hemodynamics; Humans; Myocardial Contraction; Nifedipine; Nitrogen; Perhexiline; Piperidines; Pyridines; Regional Blood Flow; Vasodilation; Verapamil | 1980 |
61 trial(s) available for perhexiline and piperidines
Article | Year |
---|---|
Supression of ventricular extrasystoles by perhexiline.
Topics: Cardiac Complexes, Premature; Circadian Rhythm; Clinical Trials as Topic; Double-Blind Method; Electrocardiography; Exercise Test; Female; Heart Ventricles; Humans; Male; Middle Aged; Perhexiline; Piperidines | 1978 |
Letter: A multicentre trial of perhexiline maleats, beta-blocker and placebo in angina pectoris.
Topics: Adrenergic beta-Antagonists; Angina Pectoris; Clinical Trials as Topic; Humans; Perhexiline; Piperidines; Placebos; Research Design | 1975 |
[Clinical examination of perhexilinemaleate efficiency in the therapy of angina pectoris].
Topics: Adult; Angina Pectoris; Chemical Phenomena; Chemistry; Clinical Trials as Topic; Female; Humans; Male; Middle Aged; Perhexiline; Piperidines | 1977 |
Long-term effect of perhexiline maleate on ventricular ectopic activity.
Topics: Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Clinical Trials as Topic; Humans; Male; Middle Aged; Myocardial Infarction; Perhexiline; Piperidines; Ventricular Fibrillation | 1978 |
The treatment of angina pectoris. A trial of perhexiline maleate in patients with angiographically normal coronary arteries.
Topics: Angina Pectoris; Clinical Trials as Topic; Double-Blind Method; Humans; Perhexiline; Piperidines | 1978 |
Comparative trial of perhexiline maleate and oxprenolol in patients with angina pectoris.
Topics: Adult; Aged; Angina Pectoris; Clinical Trials as Topic; Female; Humans; Male; Middle Aged; Oxprenolol; Perhexiline; Piperidines; Random Allocation | 1978 |
[Perhexiline maleate in a multicentric study in Brazil - a new model of a clinical protocol and mechanism of action of the drug].
Topics: Angina Pectoris; Clinical Trials as Topic; Coronary Disease; Humans; Perhexiline; Physical Exertion; Piperidines; Placebos | 1979 |
[Verapamil in the treatment of angina pectoris. Double-blind study with clinical and ergometric evaluation].
Topics: Adult; Aged; Angina Pectoris; Blood Pressure; Clinical Trials as Topic; Double-Blind Method; Electrocardiography; Exercise Test; Female; Heart Rate; Humans; Male; Middle Aged; Perhexiline; Piperidines; Placebos; Verapamil | 1979 |
A multicentre trial of perhexiline maleate in the treatment of angina pectoris.
Topics: Adult; Aged; Angina Pectoris; Clinical Trials as Topic; Drug Evaluation; Female; Humans; Male; Middle Aged; Nitroglycerin; Perhexiline; Physical Exertion; Piperidines; Time Factors | 1977 |
[Influence of perhexilinmaleat on the exercise electrocardiogram (author's transl)].
Topics: Coronary Disease; Electrocardiography; Heart Rate; Humans; Liver; Male; Perhexiline; Physical Exertion; Piperidines | 1979 |
[Clinical efficacy of perhexiline maleate in stable angina pectoris (author's transl)].
Topics: Adult; Aged; Angina Pectoris; Double-Blind Method; Exercise Test; Heart Rate; Humans; Middle Aged; Myocardial Infarction; Perhexiline; Physical Exertion; Piperidines | 1978 |
[Treatment of angina pectoris with perhexiline maleate. Clinical evaluation in controlled double-blind study with placebo and prenylamine].
Topics: Adult; Aged; Angina Pectoris; Clinical Trials as Topic; Female; Humans; Male; Maleates; Middle Aged; Perhexiline; Piperidines; Placebos; Prenylamine | 1976 |
[Experimental study on a new antianginal drug: perhexiline maleate].
Topics: Aged; Angina Pectoris; Clinical Trials as Topic; Drug Evaluation; Female; Humans; Male; Middle Aged; Perhexiline; Piperidines | 1975 |
Letter: Perhexiline maleate in angina pectoris.
Topics: Angina Pectoris; Clinical Trials as Topic; Drug Evaluation; Humans; Perhexiline; Piperidines | 1976 |
[Effects of perhexiline maleate in angina pectoris: preliminary clinical and experimental results of a comparative study].
Topics: Angina Pectoris; Clinical Trials as Topic; Drug Evaluation; Humans; Perhexiline; Piperidines; Placebos; Propranolol | 1975 |
[Perhexiline maleate in the treatment of angina pectoris].
Topics: Adult; Aged; Angina Pectoris; Clinical Trials as Topic; Drug Evaluation; Female; Humans; Male; Middle Aged; Perhexiline; Piperidines | 1976 |
[Multicentric study with perhexiline maleate in angina pectoris. Preliminary report].
Topics: Angina Pectoris; Clinical Trials as Topic; Drug Evaluation; Female; Humans; Male; Maleates; Perhexiline; Piperidines; Placebos | 1976 |
Clinical evaluation of perhexiline maleate in the treatment of patients with chronic coronary insufficiency.
Topics: Administration, Oral; Aged; Alanine Transaminase; Angina Pectoris; Animals; Arrhythmias, Cardiac; Aspartate Aminotransferases; Clinical Trials as Topic; Coronary Disease; Dose-Response Relationship, Drug; Drug Evaluation; Electrocardiography; Female; Heart Ventricles; Humans; Male; Middle Aged; Myocardial Contraction; Nitroglycerin; Oxygen Consumption; Perhexiline; Piperidines; Prognosis | 1975 |
A double-blind trial of perhexiline maleate in the prophylaxis of angina pectoris.
Topics: Adult; Aged; Angina Pectoris; Clinical Trials as Topic; Depression, Chemical; Female; Heart Rate; Humans; Male; Middle Aged; Nitroglycerin; Perhexiline; Piperidines | 1976 |
Report of a multicentre monitored release study of perhexiline maleate in the prevention of angina pectoris.
Topics: Angina Pectoris; Clinical Trials as Topic; Female; Humans; Male; Middle Aged; Nitroglycerin; Perhexiline; Piperidines | 1976 |
[Pexide, a new coronary drug].
Topics: Angina Pectoris; Animals; Arrhythmias, Cardiac; Clinical Trials as Topic; Dogs; Hemodynamics; Humans; Perhexiline; Piperidines; Placebos; Rats | 1975 |
[Perhexiline maleate in the treatment of angina pectoris - double blind study].
Topics: Adult; Aged; Angina Pectoris; Clinical Trials as Topic; Drug Evaluation; Female; Humans; Male; Middle Aged; Perhexiline; Piperidines; Placebos | 1975 |
[Clinical trial by perexiline maleate in treatment of angina pectoris (author's transl)].
Topics: Angina Pectoris; Blood Pressure; Body Weight; Drug Evaluation; Electrocardiography; Headache; Humans; Perhexiline; Piperidines; Prenylamine; Pulse; Sleep Wake Disorders | 1975 |
Effects of perhexiline maleate in patients with angina pectoris unrelieved by other antianginal agent.
Topics: Adult; Aged; Angina Pectoris; Clinical Trials as Topic; Electrocardiography; Evaluation Studies as Topic; Exercise Test; Female; Humans; Male; Middle Aged; Nitroglycerin; Pentaerythritol Tetranitrate; Perhexiline; Piperidines; Vasodilator Agents; Vertigo | 1973 |
Proceedings: Perhexiline versus prenylamine. A controlled clinical trial in coronary insufficiency.
Topics: Adult; Aged; Clinical Trials as Topic; Coronary Disease; Female; Humans; Male; Middle Aged; Nitroglycerin; Perhexiline; Piperidines; Prenylamine; Vasodilator Agents | 1973 |
Proceedings: Experience with the use of perhexiline in patients with chronic coronary insufficiency: preliminary report.
Topics: Aged; Clinical Trials as Topic; Coronary Disease; Female; Humans; Male; Middle Aged; Nitroglycerin; Perhexiline; Piperidines; Vasodilator Agents | 1973 |
Treadmill exercise-tolerance test behavior in anginal patients treated with perhexiline maleate.
Topics: Adult; Aerobiosis; Angina Pectoris; Clinical Trials as Topic; Exercise Test; Female; Heart Rate; Humans; Male; Maleates; Middle Aged; Oxygen Consumption; Perhexiline; Piperidines; Placebos; Time Factors; Vasodilator Agents | 1974 |
Effects of perhexiline on symptomatic and hemodynamic responses to exercise in patients with angina pectoris.
Topics: Adult; Aged; Angina Pectoris; Arteriosclerosis; Blood Pressure; Catheterization; Clinical Trials as Topic; Coronary Circulation; Dyspnea; Fatigue; Female; Follow-Up Studies; Heart Rate; Humans; Male; Middle Aged; Myocardium; Nitroglycerin; Oxygen Consumption; Perhexiline; Physical Exertion; Piperidines; Placebos; Vasodilator Agents | 1974 |
A new approach to the evaluation of anti-anginal drugs (with special reference to Perhexiline maleate).
Topics: Angina Pectoris; Clinical Trials as Topic; Female; Humans; Male; Methods; Perhexiline; Piperidines; Placebos; Vasodilator Agents | 1973 |
The action of perhexiline maleate in patients with angina.
Topics: Aged; Angina Pectoris; Blood Pressure; Clinical Trials as Topic; Electrocardiography; Exercise Test; Heart Rate; Humans; Male; Middle Aged; Perhexiline; Piperidines; Placebos; Spirometry; Vasodilator Agents; Vital Capacity | 1973 |
Proceedings: Perhexiline maleate in the treatment of angina pectoris: a double-blind trial.
Topics: Adult; Aged; Angina Pectoris; Clinical Trials as Topic; Female; Humans; Male; Middle Aged; Perhexiline; Piperidines; Vasodilator Agents | 1973 |
Proceedings: Double-blind clinical trial with perhexiline in out-patients with angia pectoris.
Topics: Angina Pectoris; Clinical Trials as Topic; Humans; Outpatient Clinics, Hospital; Perhexiline; Piperidines; Placebos; Prenylamine; Vasodilator Agents | 1973 |
Proceedings: A comparative study of perhexiline, beta-adrenergic blocking agents and placebos in the management of angina pectoris.
Topics: Angina Pectoris; Clinical Trials as Topic; Humans; Perhexiline; Piperidines; Placebos; Practolol; Propranolol; Vasodilator Agents | 1973 |
Proceedings: Long-term assessment of perhexiline maleate in angina pectoris.
Topics: Adult; Aged; Angina Pectoris; Clinical Trials as Topic; Female; Humans; Liver; Liver Function Tests; Male; Middle Aged; Perhexiline; Piperidines; Time Factors; Vasodilator Agents | 1973 |
Proceedings: A long-term assessment of perhexiline maleate in the management of patients with angina pectoris.
Topics: Angina Pectoris; Clinical Trials as Topic; Female; Humans; Male; Middle Aged; Perhexiline; Piperidines; Time Factors; Vasodilator Agents | 1973 |
Proceedings: Clinical evaluation of perhexiline maleate in patients with angina pectoris associated with a positive coronary artery disease index.
Topics: Angina Pectoris; Clinical Trials as Topic; Coronary Disease; Female; Humans; Male; Perhexiline; Piperidines; Vasodilator Agents | 1973 |
Proceedings: Assessment of safety data from patients on short and long-term perhexiline therapy.
Topics: Angina Pectoris; Clinical Trials as Topic; Coronary Disease; Enzyme Induction; Enzymes; Humans; Perhexiline; Piperidines; Time Factors; Vasodilator Agents | 1973 |
Proceedings: Alteration of left ventricular responses to ischemia with oral perhexiline.
Topics: Adult; Angina Pectoris; Clinical Trials as Topic; Heart; Heart Ventricles; Humans; Male; Middle Aged; Perhexiline; Piperidines; Vasodilator Agents | 1973 |
Proceedings: Clinical evaluation of perhexiline maleate in the treatment of chronic cardiac arrhythmias of patients with coronary heart disease.
Topics: Aged; Arrhythmias, Cardiac; Clinical Trials as Topic; Coronary Disease; Electrocardiography; Female; Humans; Male; Middle Aged; Perhexiline; Piperidines; Vasodilator Agents | 1973 |
Proceedings: Evaluation of anti-arrhythmic efficacy of perhexiline maleate in ambulatory patients by Holter monitoring.
Topics: Adult; Aged; Arrhythmias, Cardiac; Clinical Trials as Topic; Electrocardiography; Female; Humans; Male; Middle Aged; Monitoring, Physiologic; Perhexiline; Piperidines; Vasodilator Agents | 1973 |
Proceedings: Effects of perhexiline maleate in angina pectoris: a double-blind clinical evaluation with ECG-treadmill exercise testing.
Topics: Adult; Aged; Angina Pectoris; Clinical Trials as Topic; Electrocardiography; Exercise Test; Female; Heart Rate; Humans; Male; Middle Aged; Perhexiline; Piperidines; Vasodilator Agents | 1973 |
Proceedings: Influence of perhexiline on the effort tolerance test in angina pectoris. Comparison with placebo and prenylamine.
Topics: Aged; Angina Pectoris; Clinical Trials as Topic; Exercise Test; Female; Humans; Male; Middle Aged; Perhexiline; Piperidines; Placebos; Prenylamine; Vasodilator Agents | 1973 |
Proceedings: Perhexiline maleate: a new anti-anginal drug.
Topics: Adult; Aged; Angina Pectoris; Clinical Trials as Topic; Female; Humans; Male; Middle Aged; Perhexiline; Piperidines; Vasodilator Agents | 1973 |
Proceedings: Perhexiline maleate: eighteen months of continuous administration in patients with angina pectoris.
Topics: Adult; Aged; Alanine Transaminase; Angina Pectoris; Aspartate Aminotransferases; Clinical Trials as Topic; Female; Humans; Male; Middle Aged; Perhexiline; Piperidines; Time Factors; Vasodilator Agents | 1973 |
Proceedings: Clinical experience with perhexiline maleate in forty-six patients with angina.
Topics: Adult; Aged; Angina Pectoris; Anticoagulants; Clinical Trials as Topic; Female; Humans; Male; Middle Aged; Perhexiline; Piperidines; Transaminases; Vasodilator Agents | 1973 |
Proceedings: Clinical and statistical evaluation of the effect of perhexiline maleate in patients with chronic angina.
Topics: Angina Pectoris; Chronic Disease; Clinical Trials as Topic; Humans; Middle Aged; Perhexiline; Piperidines; Statistics as Topic; Vasodilator Agents | 1973 |
Proceedings: Clinical evaluation of perhexiline maleate in patients with angina pectoris.
Topics: Adult; Aged; Angina Pectoris; Clinical Trials as Topic; Female; Humans; Male; Middle Aged; Perhexiline; Piperidines; Vasodilator Agents | 1973 |
Proceedings: Clinical results with a new antianginal drug (perhexiline maleate).
Topics: Angina Pectoris; Body Weight; Clinical Trials as Topic; Humans; Perhexiline; Piperidines; Vasodilator Agents | 1973 |
[Clinical evaluation of perhexiline maleate in angina patients].
Topics: Adult; Aged; Angina Pectoris; Clinical Trials as Topic; Evaluation Studies as Topic; Female; Humans; Male; Middle Aged; Perhexiline; Piperidines; Placebos; Vasodilator Agents | 1973 |
The action of perhexiline maleate in patients with angina and its effect on liver function.
Topics: Adult; Aged; Angina Pectoris; Chemical and Drug Induced Liver Injury; Clinical Trials as Topic; Dose-Response Relationship, Drug; Evaluation Studies as Topic; Hemodynamics; Humans; Liver; Liver Function Tests; Middle Aged; Perhexiline; Piperidines; Placebos; Vasodilator Agents | 1973 |
[Perhexiline maleate in angina pectoris. Study of tolerance to treadmill exercise].
Topics: Aged; Angina Pectoris; Clinical Trials as Topic; Electrocardiography; Evaluation Studies as Topic; Exercise Test; Heart Rate; Humans; Male; Middle Aged; Perhexiline; Physical Exertion; Piperidines; Vasodilator Agents | 1973 |
Assessment of perhexiline maleate in ischaemic heart disease.
Topics: Aged; Angina Pectoris; Clinical Trials as Topic; Evaluation Studies as Topic; Female; Humans; Male; Middle Aged; Perhexiline; Piperidines; Time Factors; Vasodilator Agents | 1973 |
[Perhexiline maleate in angina pectoris. Cross double blind evaluation controlled with placebo].
Topics: Angina Pectoris; Blood Pressure; Clinical Trials as Topic; Evaluation Studies as Topic; Humans; Male; Middle Aged; Perhexiline; Piperidines; Placebos; Pulse; Vasodilator Agents | 1973 |
[A new anti-angina drug: Perhexiline maleate. Apropos of 50 cases].
Topics: Angina Pectoris; Clinical Trials as Topic; Drug Evaluation; Drug Tolerance; Electrocardiography; Female; Humans; Male; Maleates; Perhexiline; Piperidines; Vasodilator Agents | 1973 |
Perhexiline maleate in the management of patients with angina pectoris. A long-term assessment.
Topics: Aged; Angina Pectoris; Arrhythmias, Cardiac; Aspartate Aminotransferases; Clinical Trials as Topic; Drug Evaluation; Electrocardiography; Female; Humans; Male; Middle Aged; Perhexiline; Piperidines; Placebos; Time Factors; Vasodilator Agents | 1974 |
Perhexiline maleate, a new anti-anginal drug, evaluated by "modified double blind double cross over study".
Topics: Administration, Oral; Adult; Aged; Alanine Transaminase; Angina Pectoris; Blood Pressure; Body Weight; Central Nervous System Diseases; Clinical Trials as Topic; Drug Evaluation; Electrocardiography; Female; Gastrointestinal Diseases; Heart Rate; Humans; Male; Middle Aged; Perhexiline; Physical Exertion; Piperidines; Placebos; Tachycardia; Vasodilator Agents | 1974 |
[Study of perhexiline maleate in the treatment of severe chronic coronary insufficiency].
Topics: Adult; Aged; Angina Pectoris; Clinical Trials as Topic; Coronary Disease; Female; Humans; Male; Maleates; Middle Aged; Perhexiline; Piperidines; Vasodilator Agents | 1974 |
[New treatment in coronary insufficiency: perhexiline maleate].
Topics: Adult; Aged; Coronary Disease; Electrocardiography; Female; Humans; Male; Middle Aged; Perhexiline; Piperidines; Placebos; Vasodilator Agents | 1973 |
Proceedings: A controlled study of the diuretic and natriuretic properties of perhexiline maleate in normal human volunteers.
Topics: Adult; Chlorides; Diuresis; Humans; Male; Middle Aged; Natriuresis; Perhexiline; Piperidines; Vasodilator Agents | 1973 |
[Drug monitoring and liver diseases induced by perhexiline maleate].
Topics: Chemical and Drug Induced Liver Injury; Clinical Trials as Topic; France; Humans; Perhexiline; Piperidines | 1981 |
[Anti-arrhythmic effect of perhexiline].
Topics: Aged; Anti-Arrhythmia Agents; Clinical Trials as Topic; Coronary Disease; Double-Blind Method; Female; Humans; Male; Middle Aged; Perhexiline; Piperidines | 1981 |
168 other study(ies) available for perhexiline and piperidines
Article | Year |
---|---|
Long-term perhexiline maleate and liver function.
Topics: Dose-Response Relationship, Drug; gamma-Glutamyltransferase; Humans; Isocitrate Dehydrogenase; Liver; Liver Function Tests; Male; Perhexiline; Piperidines; Sulfobromophthalein | 1976 |
[Role of perhexiline maleate and beta blocking agents in the development of severe hypoglycemia].
Topics: Adrenergic beta-Antagonists; Aged; Female; Humans; Hypoglycemia; Male; Middle Aged; Perhexiline; Piperidines | 1976 |
Cardiovascular effects of isoproterenol and possible antagonistic actions of propranolol and perhexiline.
Topics: Adrenergic beta-Antagonists; Animals; Blood Pressure; Cardiac Output; Dogs; Female; Heart Rate; Hemodynamics; In Vitro Techniques; Isoproterenol; Male; Myocardial Contraction; Perhexiline; Piperidines; Propranolol; Rabbits | 1978 |
Perhexiline maleate in the treatment of angina pectoris. Five years of personal clinical experience.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Angina Pectoris; Australia; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Myocardial Infarction; Perhexiline; Piperidines; Prognosis | 1978 |
[Perhexilinemaleate--a new monodrug in the field of coronary therapeutic agents].
Topics: Angina Pectoris; Cardiac Complexes, Premature; Congresses as Topic; Coronary Disease; Germany, West; Humans; Maleates; Perhexiline; Piperidines | 1975 |
The anti-arrhythmic effects of perhexiline maleate in patients with ischaemic heart disease.
Topics: Arrhythmias, Cardiac; Atrial Fibrillation; Cardiac Complexes, Premature; Coronary Disease; Female; Heart Ventricles; Humans; Male; Middle Aged; Perhexiline; Piperidines | 1975 |
[Letter: Perhexilinemaleate in patients suffering from chronic coronary failure].
Topics: Adult; Aged; Chronic Disease; Coronary Disease; Drug Tolerance; Female; Humans; Male; Maleates; Middle Aged; Palliative Care; Perhexiline; Piperidines | 1976 |
Liver ganglioside storage after perhexiline maleate.
Topics: Aged; Chemical and Drug Induced Liver Injury; Coronary Disease; Cytoplasm; Gangliosides; Gangliosidoses; Humans; Liver; Male; Middle Aged; Perhexiline; Piperidines | 1977 |
Liver damage after perhexiline maleate.
Topics: Angina Pectoris; Chemical and Drug Induced Liver Injury; Humans; Male; Middle Aged; Perhexiline; Piperidines | 1977 |
Liver damage after perhexiline maleate.
Topics: Aged; Alcoholism; Female; Humans; Liver; Male; Middle Aged; Necrosis; Perhexiline; Piperidines | 1977 |
Peripheral-nerve lipid abnormalities in patients on perhexiline maleate.
Topics: Gangliosides; Humans; Maleates; Perhexiline; Peripheral Nerves; Peripheral Nervous System Diseases; Piperidines | 1977 |
Liver during perhexiline hypoglycaemia.
Topics: Coronary Disease; Female; Glucose-6-Phosphatase; Humans; Hypoglycemia; Liver; Liver Glycogen; Middle Aged; Perhexiline; Piperidines | 1977 |
[Electrophysiological study of latent neuropathies induced by perhexiline].
Topics: Adult; Aged; Angina Pectoris; Electric Stimulation; Evoked Potentials; H-Reflex; Humans; Middle Aged; Neural Conduction; Perhexiline; Peripheral Nerves; Peripheral Nervous System Diseases; Piperidines | 1978 |
Perhexilene mimicking bronchial carcinoma.
Topics: Bronchial Neoplasms; Diagnostic Errors; Humans; Male; Middle Aged; Neuromuscular Diseases; Perhexiline; Piperidines | 1978 |
Treatment of variant angina pectoris with perhexilene maleate.
Topics: Angina Pectoris; Angina Pectoris, Variant; Coronary Angiography; Drug Evaluation; Electrocardiography; Female; Humans; Male; Middle Aged; Nitroglycerin; Perhexiline; Piperidines | 1979 |
[Perhexiline-maleate-induced lipidosis in mouse spinal ganglia tissue culture. Preliminary results on the acute toxicity on the drug].
Topics: Animals; Culture Techniques; Ganglia, Spinal; Lipidoses; Mice; Microscopy, Electron; Perhexiline; Piperidines | 1978 |
[Occurrence of Equilibrium disorders during treatment with vasodilator agents. Perhixiline maleate].
Topics: Humans; Perhexiline; Piperidines; Vertigo | 1975 |
[Letter: Peripheral neuropathy after prolonged adsorption of perhexiline maleate. 2 cases].
Topics: Aged; Angina Pectoris; Humans; Male; Maleates; Paresthesia; Parkinson Disease, Secondary; Perhexiline; Peripheral Nervous System Diseases; Piperidines | 1975 |
Polyneuropathy after perhexiline maleate therapy.
Topics: Humans; Male; Middle Aged; Myocardial Infarction; Perhexiline; Peripheral Nervous System Diseases; Piperidines; Schwann Cells | 1976 |
[A case of polyradiculoneuritis following prolonged treatment with perhexiline maleate].
Topics: Coronary Disease; Female; Humans; Long-Term Care; Middle Aged; Perhexiline; Piperidines; Polyradiculopathy | 1976 |
[Electron microscopic study of nerve, muscle and skin lesions induced by perhexiline maleate (author's transl)].
Topics: Aged; Angina Pectoris; Female; Humans; Male; Microscopy, Electron; Middle Aged; Muscles; Muscular Atrophy; Nerve Degeneration; Perhexiline; Peripheral Nerves; Peripheral Nervous System Diseases; Piperidines; Schwann Cells; Skin | 1977 |
Peripheral and autonomic neuropathy after treatment with perhexiline maleate.
Topics: Autonomic Nervous System; Diabetic Neuropathies; Humans; Male; Middle Aged; Nervous System Diseases; Perhexiline; Peripheral Nervous System Diseases; Piperidines | 1977 |
[Electromyogram and nervous conduction speeds during prolonged treatment by perhexiline maleate (author's transl)].
Topics: Adult; Aged; Angina Pectoris; Electromyography; Female; Humans; Long-Term Care; Male; Middle Aged; Neural Conduction; Perhexiline; Peripheral Nervous System Diseases; Piperidines | 1977 |
[Peripheral neuropathies due to perhexiline maleate (author's transl)].
Topics: Humans; Male; Middle Aged; Perhexiline; Peripheral Nervous System Diseases; Piperidines | 1977 |
[Peripheral neuropathies during treatment with perhexilline maleate (apropos of 10 cases)].
Topics: Aged; Female; Humans; Middle Aged; Perhexiline; Peripheral Nervous System Diseases; Piperidines; Time Factors | 1977 |
[Post-arteriographic thrombosis of the ophthalmic veins in 2 cases of peripheral neuropathy with central neurological signs due to perhexiline maleate].
Topics: Cerebral Angiography; Eye; Humans; Neurologic Manifestations; Perhexiline; Peripheral Nervous System Diseases; Piperidines; Thrombosis; Veins | 1977 |
[Ultrastructural study of the liver after treatment with perhexiline maleate].
Topics: Aged; Angina Pectoris; Chemical and Drug Induced Liver Injury; Female; Humans; Liver; Perhexiline; Piperidines | 1977 |
[Oedematous optic neuropathy from Perhexilline maleate associated with peripheral polyneuropathy (author's transl)].
Topics: Humans; Intracranial Pressure; Male; Middle Aged; Optic Nerve Diseases; Papilledema; Perhexiline; Peripheral Nervous System Diseases; Piperidines | 1977 |
Perhexilline-induced neuropathy.
Topics: Aged; Autonomic Nervous System; Female; Humans; Male; Middle Aged; Nervous System Diseases; Perhexiline; Peripheral Nervous System Diseases; Piperidines | 1978 |
Perhexiline induces generalized lipidosis in rats.
Topics: Animals; Inclusion Bodies; Lipidoses; Perhexiline; Piperidines; Rats | 1978 |
[Diffuse polymorphous inclusions in a patient treated with perhexiline maleate (author's transl)].
Topics: Biopsy; Chemical and Drug Induced Liver Injury; Humans; Inclusion Bodies; Lipidoses; Liver; Male; Middle Aged; Neuritis; Perhexiline; Piperidines; Schwann Cells | 1978 |
Perhexiline neuropathy: a clinicopathological study.
Topics: Aged; Angina Pectoris; Demyelinating Diseases; Female; Humans; Male; Middle Aged; Nerve Fibers; Perhexiline; Peripheral Nervous System Diseases; Piperidines | 1978 |
Morphological changes in CNS of rats treated with perhexiline maleate (pexid).
Topics: Animals; Astrocytes; Body Weight; Brain; Central Nervous System; Endothelium; Ependyma; Fibroblasts; Inclusion Bodies; Microscopy, Electron; Neurons; Oligodendroglia; Perhexiline; Piperidines; Rats | 1978 |
[Neurological disorders and perhexiline maleate therapy. Clinical study of 10 cases. Neuropathological, pharmacocinetic and biochemical studies (author's transl)].
Topics: Cerebellar Diseases; Coronary Disease; Demyelinating Diseases; Endothelium; Humans; Inclusion Bodies; Perhexiline; Peripheral Nerves; Peripheral Nervous System Diseases; Piperidines; Schwann Cells; Spinal Cord Diseases | 1978 |
Perhexiline maleate-induced cirrhosis.
Topics: Aged; Angina Pectoris; Chemical and Drug Induced Liver Injury; Cytoplasmic Granules; Female; Hepatic Encephalopathy; Humans; Inclusion Bodies; Liver; Liver Cirrhosis; Male; Middle Aged; Necrosis; Perhexiline; Piperidines | 1979 |
Polyneuropathy with normal metabolism of perhexiline maleate.
Topics: Aged; Female; Humans; Perhexiline; Peripheral Nervous System Diseases; Piperidines | 1978 |
Analysis of the major lipid classes in human peripheral nerve biopsies. Age group differences and abnormalities of ganglioside level in perhexiline maleate therapy.
Topics: Adolescent; Adult; Age Factors; Aged; Child; Child, Preschool; Gangliosides; Glycolipids; Humans; Infant; Lipids; Middle Aged; Perhexiline; Peripheral Nerves; Peripheral Nervous System Diseases; Peroneal Nerve; Phospholipids; Piperidines | 1979 |
Perhexiline maleate and peripheral neuropathy.
Topics: Adult; Aged; Angina Pectoris; Electromyography; Female; Follow-Up Studies; Humans; Male; Middle Aged; Motor Neurons; Muscular Atrophy; Neural Conduction; Perhexiline; Peripheral Nervous System Diseases; Peroneal Nerve; Piperidines; Ulnar Nerve | 1979 |
Pexid-induced rat retinal pathology.
Topics: Animals; Inclusion Bodies; Microscopy, Electron; Neurons; Perhexiline; Pigment Epithelium of Eye; Piperidines; Rats; Retina | 1979 |
[Influence of perhexiline maleate on the electrocardiographic signs of myocardial ischemia. Ergometric study].
Topics: Coronary Disease; Drug Evaluation; Electrocardiography; Exercise Test; Female; Heart Conduction System; Humans; Male; Middle Aged; Perhexiline; Piperidines | 1977 |
Liver damage associated with perhexiline maleate.
Topics: Aged; Angina Pectoris; Chemical and Drug Induced Liver Injury; Humans; Liver; Male; Middle Aged; Perhexiline; Piperidines | 1979 |
The effects of perhexiline on the sympathetic nervous system.
Topics: Animals; Autonomic Fibers, Postganglionic; Autonomic Fibers, Preganglionic; Dogs; Electric Stimulation; Guinea Pigs; Heart; Heart Rate; In Vitro Techniques; Isoproterenol; Male; Muscle Contraction; Muscle, Smooth; Myocardium; Norepinephrine; Perhexiline; Piperidines; Rats; Sympathetic Nervous System; Vagotomy; Vas Deferens | 1979 |
Provocative testing with ergonovine to evaluate the efficacy of treatment with calcium antagonists in variant angina.
Topics: Adult; Aged; Angina Pectoris; Angina Pectoris, Variant; Electrocardiography; Ergonovine; Evaluation Studies as Topic; Female; Humans; Male; Middle Aged; Nifedipine; Perhexiline; Piperidines; Pyridines | 1979 |
Long-term safety of perhexiline maleate.
Topics: Angina Pectoris; Body Weight; Humans; Liver Diseases; Neuromuscular Diseases; Perhexiline; Piperidines | 1979 |
[Acute hepatic failure due to perhexiline maleate].
Topics: Aged; Angina Pectoris; Chemical and Drug Induced Liver Injury; Humans; Liver Cirrhosis; Male; Perhexiline; Piperidines; Time Factors | 1979 |
Effects of glucagon, histamine, and perhexiline on the ischemic canine mesenteric circulation.
Topics: Animals; Digoxin; Dogs; Female; Glucagon; Hemodynamics; Histamine; Ileum; Ischemia; Jejunum; Male; Mesenteric Arteries; Perhexiline; Piperidines | 1979 |
Perhexiline maleate in the treatment of severe angina pectoris.
Topics: Alprenolol; Angina Pectoris; Drug Therapy, Combination; Electrocardiography; Female; Humans; Male; Middle Aged; Perhexiline; Piperidines; Propranolol | 1979 |
The effects of perhexiline maleate (Pexid) and alcohol on rat liver.
Topics: Animals; Chemical and Drug Induced Liver Injury; Drug Synergism; Ethanol; Liver; Liver Diseases; Male; Microscopy, Electron; Perhexiline; Piperidines; Rats | 1979 |
Perhexiline maleate.
Topics: Aged; Humans; Male; Perhexiline; Piperidines; Polyradiculoneuropathy; Substance Withdrawal Syndrome | 1979 |
Effect of perhexiline maleate on lipid metabolism in the rat. II. Liver and lung phospholipids after administration of high doses of perhexiline maleate.
Topics: Animals; Liver; Lung; Male; Perhexiline; Phospholipids; Piperidines; Rats | 1979 |
[Muscular and nerve changes induced by perhexiline maleate with diabetic type microangiopathy (author's transl)].
Topics: Aged; Diabetic Angiopathies; Female; Follow-Up Studies; Humans; Male; Muscles; Neuromuscular Diseases; Perhexiline; Peripheral Nerves; Piperidines | 1979 |
[The liver and perhexiline maleate].
Topics: Chemical and Drug Induced Liver Injury; Humans; Liver; Perhexiline; Piperidines | 1979 |
[Histoenzymologic modifications induced by perhexiline maleate in human liver].
Topics: Aged; Chemical and Drug Induced Liver Injury; Humans; Liver; Middle Aged; Perhexiline; Piperidines | 1979 |
Liver damage due to perhexiline maleate.
Topics: Chemical and Drug Induced Liver Injury; Diagnosis, Differential; Hepatitis, Alcoholic; Humans; Liver; Liver Diseases; Male; Middle Aged; Perhexiline; Piperidines | 1979 |
Effect of perhexiline maleate on lipid metabolism in the rat.
Topics: Animals; Body Weight; Lipid Metabolism; Lipids; Liver; Lung; Male; Organ Size; Perhexiline; Piperidines; Rats | 1979 |
[Various new anti-angina medications].
Topics: Amiodarone; Angina Pectoris; Benzofurans; Humans; Isosorbide Dinitrate; Perhexiline; Piperidines | 1977 |
Perhexiline maleate toxicity: a case of severe jaundice.
Topics: Adult; Angina Pectoris; Humans; Jaundice; Male; Perhexiline; Piperidines | 1977 |
[Hepatitis due to perhexiline maleate. Development of cirrhosis after interruption of the drug. Report of two cases (author's transl)].
Topics: Aged; Chemical and Drug Induced Liver Injury; Humans; Liver; Liver Cirrhosis; Male; Middle Aged; Perhexiline; Piperidines | 1977 |
Raised intracranial pressure due to perhexiline maleate.
Topics: Adult; Angina Pectoris; Female; Humans; Intracranial Pressure; Male; Middle Aged; Papilledema; Perhexiline; Piperidines | 1978 |
Papilloedema in patients taking perhexiline maleate.
Topics: Humans; Intracranial Pressure; Male; Middle Aged; Papilledema; Perhexiline; Piperidines | 1978 |
Papilloedema in patients taking perhexiline maleate.
Topics: Cerebrospinal Fluid Proteins; Humans; Papilledema; Perhexiline; Piperidines | 1978 |
Prevalence of latent perhexiline neuropathy.
Topics: Angina Pectoris; H-Reflex; Humans; Nervous System Diseases; Perhexiline; Piperidines | 1978 |
[Can one give perhexiline to diabetics?].
Topics: Angina Pectoris; Body Weight; Chemical and Drug Induced Liver Injury; Diabetes Complications; Diabetes Mellitus; Humans; Hypoglycemia; Neurologic Manifestations; Perhexiline; Piperidines; Polyneuropathies; Triglycerides | 1978 |
[Comparative studies on perhexiline, nifedipine and practolol in the light of spirometric and ergometric examinations].
Topics: Coronary Disease; Humans; Nifedipine; Perhexiline; Physical Exertion; Piperidines; Practolol; Pyridines; Spirometry | 1978 |
[Hepatitis and acute renal failure following halothane anaesthesia in a patient treated with perhexiline maleate (author's transl)].
Topics: Acute Kidney Injury; Aged; Angina Pectoris; Chemical and Drug Induced Liver Injury; Drug Synergism; Female; Halothane; Humans; Perhexiline; Piperidines | 1978 |
[Perhexilline maleate: relationship between side-effects, plasma concentrations and rate of metabolism (author's transl)].
Topics: Adult; Biotransformation; Blood Glucose; Female; Half-Life; Humans; Inactivation, Metabolic; Male; Middle Aged; Perhexiline; Piperidines; Transaminases | 1978 |
[Liver cirrhosis after 2 years of perhexiline maleate treatment].
Topics: Angina Pectoris; Diagnosis, Differential; Hepatitis, Alcoholic; Humans; Liver Cirrhosis; Male; Middle Aged; Perhexiline; Piperidines; Time Factors | 1978 |
[Comparative study of the medium term use of verapamil and perhexiline in the treatment of chronic coronary insufficiency. Clinical and cycloergometric evaluation].
Topics: Adult; Aged; Chronic Disease; Coronary Disease; Electrocardiography; Exercise Test; Female; Humans; Male; Middle Aged; Perhexiline; Piperidines; Placebos; Verapamil | 1978 |
Perhexiline maleate-induced hepatitis.
Topics: Aged; Chemical and Drug Induced Liver Injury; Female; Humans; Liver; Male; Middle Aged; Perhexiline; Piperidines; Time Factors | 1978 |
[Hepatic lesions due to perhexiline maleate (author's transl)].
Topics: Aged; Chemical and Drug Induced Liver Injury; Coronary Disease; Female; Humans; Liver; Male; Middle Aged; Perhexiline; Piperidines; Transaminases | 1978 |
Comparative effects of amiodarone, perhexiline and bepridil on the cardiac rhythms of the unanesthetized dog in chronic heart block.
Topics: Amines; Amiodarone; Animals; Benzofurans; Benzylamines; Dogs; Female; Heart Block; Heart Rate; Male; Perhexiline; Piperidines; Pyrrolidines; Time Factors | 1978 |
[Perhexilene maleate--a new drug for the treatment of angina pectoris].
Topics: Angina Pectoris; Humans; Perhexiline; Piperidines | 1978 |
Pharmacokinetics of perhexiline maleate in anginal patients with and without peripheral neuropathy.
Topics: Aged; Angina Pectoris; Female; Humans; Kinetics; Male; Middle Aged; Nervous System Diseases; Perhexiline; Piperidines; Time Factors | 1978 |
Perhexiline maleate neurotoxicity and weight loss.
Topics: Aged; Body Weight; Female; Humans; Male; Middle Aged; Nervous System Diseases; Perhexiline; Piperidines | 1978 |
Ataxia during perhexiline maleate therapy.
Topics: Ataxia; Humans; Male; Middle Aged; Perhexiline; Piperidines | 1978 |
[Papillary edema and perhexiline maleate].
Topics: Aged; Coronary Disease; Female; Humans; Male; Middle Aged; Myocardial Infarction; Papilledema; Perhexiline; Piperidines | 1978 |
[Anti-arrhythmic action of perhexiline maleate in chronic coronary insufficiency].
Topics: Adult; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Chronic Disease; Coronary Disease; Drug Evaluation; Female; Humans; Male; Middle Aged; Perhexiline; Piperidines; Placebos | 1977 |
Effects of perhexiline on survival time and infarct size in experimental myocardial infarction.
Topics: Animals; Arrhythmias, Cardiac; Blood Pressure; Coronary Vessels; Creatine Kinase; Dogs; Electrocardiography; Female; Heart; Heart Rate; Male; Myocardial Infarction; Myocardium; Oxygen Consumption; Perhexiline; Piperidines; Time Factors | 1977 |
Polyneuropathy during perhexiline maleate therapy.
Topics: Aged; Humans; Male; Nervous System Diseases; Perhexiline; Piperidines | 1977 |
[Polyradiculitis, cerebellar manifestations, Parkinsonian tremor, papillary edema and hemorrhages in eye grounds during treatment with perhexilline maleate: regressive pathology].
Topics: Brain Diseases; Cerebellum; Female; Humans; Iatrogenic Disease; Middle Aged; Parkinson Disease, Secondary; Perhexiline; Piperidines; Polyradiculopathy; Retinal Hemorrhage | 1977 |
Proximal myopathy after perhexiline maleate treatment.
Topics: Aged; Angina Pectoris; Female; Humans; Muscular Diseases; Perhexiline; Piperidines | 1977 |
[Hypoglycemia in 2 patients treated with perhexiline maleate].
Topics: Aged; Angina Pectoris; Blood Glucose; Female; Glucagon; Humans; Hypoglycemia; Insulin; Male; Perhexiline; Piperidines | 1977 |
Adverse reactions to perhexiline (Pexid).
Topics: Humans; Perhexiline; Piperidines | 1977 |
Effects of sustained isometric handgrip on ventricular systolic time intervals in patients with ischemic heart disease. Inotropic state of the left ventricle during treatment with perhexiline maleate and with propranolol.
Topics: Aged; Blood Pressure; Coronary Disease; Electrocardiography; Female; Hand; Heart Rate; Humans; Isometric Contraction; Male; Middle Aged; Perhexiline; Physical Exertion; Piperidines; Placebos; Propranolol | 1977 |
[Effect of perhexiline maleate on the electrocardiogram].
Topics: Adult; Aged; Electrocardiography; Female; Heart Diseases; Heart Rate; Humans; Male; Middle Aged; Perhexiline; Piperidines; Pulse | 1977 |
[Antiarrhythmic and antianginose activity of perhexiline maleate].
Topics: Adult; Aged; Angina Pectoris; Arrhythmias, Cardiac; Drug Evaluation; Female; Humans; Male; Middle Aged; Perhexiline; Piperidines | 1977 |
[Hepatic overload of gangliosides after perhexiline maleate. Morphological and biochemical course (author's transl)].
Topics: Aged; Drug Hypersensitivity; Gangliosides; Humans; Liver; Male; Perhexiline; Piperidines | 1977 |
[Spiroergometric studies following perhexiline administration in patients with coronary disease].
Topics: Adult; Coronary Disease; Hemodynamics; Humans; Middle Aged; Perhexiline; Piperidines; Spirometry | 1977 |
Effect of chronic administration of perhexiline on pacing-induce S-T segment depression in the atherosclerotic rabbit.
Topics: Angina Pectoris; Animals; Arteriosclerosis; Disease Models, Animal; Electrocardiography; Heart Rate; Male; Perhexiline; Piperidines; Rabbits | 1976 |
[Subacute toxic hepatitis and perhexiline maleates].
Topics: Acute Disease; Aged; Chemical and Drug Induced Liver Injury; Female; Humans; Liver; Male; Middle Aged; Perhexiline; Piperidines; Transaminases | 1976 |
[Long-term study of exercise tolerance in angina patients treated with perhexiline].
Topics: Adult; Aged; Angina Pectoris; Exercise Test; Humans; Male; Middle Aged; Perhexiline; Piperidines | 1976 |
Possible mechanism of action of perhexiline maleate on heart mitochondria.
Topics: Animals; Aspartate Aminotransferases; Electron Transport; Malate Dehydrogenase; Male; Mitochondria, Muscle; Myocardium; NADH, NADPH Oxidoreductases; Oxaloacetates; Oxidative Phosphorylation; Oxygen Consumption; Perhexiline; Piperidines; Rats; Succinate Dehydrogenase; Ubiquinone | 1976 |
[2 new anti-angina drugs: amiodarone and perhexiline maleate. Advantages and adverse effects].
Topics: Amiodarone; Angina Pectoris; Benzofurans; Humans; Perhexiline; Piperidines | 1976 |
Perhexiline in angina pectoris.
Topics: Angina Pectoris; Animals; Humans; Perhexiline; Piperidines | 1976 |
Perhexiline maleate in angina pectoris.
Topics: Adult; Aged; Angina Pectoris; Female; Humans; Male; Middle Aged; Perhexiline; Piperidines | 1976 |
[Letter: Side effects of perhexiline maleate. Identification of a population with an increased risk of intolerance].
Topics: Age Factors; Coronary Disease; Female; Humans; Male; Maleates; Perhexiline; Piperidines; Sex Factors; Vertigo; Vestibular Nuclei | 1975 |
[Letter: Perhexiline maleate and extrapyramidal syndrome].
Topics: Aged; Basal Ganglia Diseases; Coronary Disease; Humans; Male; Maleates; Myocardial Infarction; Perhexiline; Piperidines | 1975 |
Electrophysiologic properties of perhexiline.
Topics: Animals; Arrhythmias, Cardiac; Bundle of His; Dogs; Electric Stimulation; Electrocardiography; Heart; Heart Conduction System; Heart Rate; Perhexiline; Piperidines | 1975 |
[Letter: Hypoglycemia after perhexiline maleate].
Topics: Aged; Angina Pectoris; Female; Humans; Hypoglycemia; Maleates; Perhexiline; Piperidines | 1975 |
[1st results of median term treatment with perhexiline maleate in a group of patients with severe coronary insufficiency].
Topics: Adult; Aged; Coronary Disease; Drug Evaluation; Female; Heart Rate; Humans; Male; Middle Aged; Perhexiline; Piperidines; Time Factors | 1975 |
[Use of perhexiline maleate in angina pectoris].
Topics: Aged; Angina Pectoris; Drug Evaluation; Humans; Male; Middle Aged; Perhexiline; Piperidines | 1975 |
[Clinical, polygraphic and echocardiographic evaluation of the action of perhexeline maleate in angina patients].
Topics: Angina Pectoris; Drug Evaluation; Echocardiography; Electrocardiography; Heart; Humans; Perhexiline; Phonocardiography; Piperidines | 1975 |
[Letter: 7 peripheral neuropathies after treatment by perhexiline maleate].
Topics: Cerebrospinal Fluid Proteins; Demyelinating Diseases; Humans; Perhexiline; Piperidines; Polyradiculopathy | 1976 |
[Letter: Subacute toxic hepatitis following perhexiline maleate therapy].
Topics: Acute Disease; Chemical and Drug Induced Liver Injury; Female; Humans; Maleates; Middle Aged; Perhexiline; Piperidines | 1976 |
Effects of perhexiline maleate on coronary flow distribution in the ischemic canine myocardium.
Topics: Animals; Coronary Circulation; Coronary Disease; Dogs; Lung; Myocardium; Oxygen Consumption; Perhexiline; Piperidines | 1976 |
[Anti-arrhythmic properties of perhexiline maleate. Study by dynamic electrocardiography].
Topics: Anti-Arrhythmia Agents; Cardiac Complexes, Premature; Electrocardiography; Evaluation Studies as Topic; Heart Rate; Humans; Methods; Perhexiline; Piperidines; Vasodilator Agents | 1973 |
[Clinical trial of a new anti-angina agent: perhexiline maleate].
Topics: Adult; Aged; Angina Pectoris; Electrocardiography; Female; Humans; Male; Middle Aged; Nitroglycerin; Perhexiline; Piperidines; Vasodilator Agents | 1973 |
[Letter: Equilibrium disorders induced by perhexiline maleate].
Topics: Humans; Hyperesthesia; Maleates; Nystagmus, Pathologic; Perhexiline; Piperidines; Postural Balance; Vertigo; Vestibular Function Tests | 1974 |
[Perhexiline maleate in coronary insufficiency. Clinical research].
Topics: Administration, Oral; Adult; Aged; Angina Pectoris; Coronary Disease; Electrocardiography; Female; Humans; Male; Maleates; Middle Aged; Perhexiline; Piperidines | 1974 |
[Letter: Weight reduction and perhexiline maleate].
Topics: Body Weight; Coronary Disease; Diuresis; Feeding and Eating Disorders; Humans; Maleates; Perhexiline; Piperidines; Vasodilator Agents | 1974 |
Proceedings: Effects of perhexiline on the electrophysiologic activity of mammalian heart.
Topics: Animals; Dogs; Electrophysiology; Heart; In Vitro Techniques; Perhexiline; Piperidines; Rabbits; Vasodilator Agents | 1973 |
Proceedings: The absorption, excretion and metabolism of perhexiline maleate by the human.
Topics: Adult; Carbon Radioisotopes; Humans; Intestinal Absorption; Male; Perhexiline; Piperidines; Vasodilator Agents | 1973 |
[Letter: Secondary but reversible effects of perhexilin administration].
Topics: Chemical and Drug Induced Liver Injury; Coronary Disease; Female; Humans; Middle Aged; Perhexiline; Piperidines; Vasodilator Agents | 1973 |
Effects of perhexiline on left ventricular responses to exercise and atrial pacing.
Topics: Angina Pectoris; Evaluation Studies as Topic; Heart Ventricles; Hemodynamics; Humans; Perhexiline; Physical Exertion; Piperidines; Vasodilator Agents | 1973 |
[Letter: Nonspecific abnormalities of ventricular repolarization induced by perhexiline (apropos of 3 cases)].
Topics: Angina Pectoris; Electrocardiography; Perhexiline; Piperidines; Vasodilator Agents | 1974 |
[Letter: Electrocardiographic changes due to perhexiline maleate].
Topics: Aged; Angina Pectoris; Electrocardiography; Humans; Male; Perhexiline; Piperidines; Vasodilator Agents | 1974 |
Effects of perhexiline on coronary hemodynamic and myocardial metabolic responses to tachycardia.
Topics: Adult; Angina Pectoris; Blood Flow Velocity; Blood Pressure; Cardiac Output; Coronary Circulation; Coronary Vessels; Heart Rate; Humans; Lactates; Middle Aged; Myocardium; Oxygen Consumption; Pacemaker, Artificial; Perhexiline; Piperidines; Tachycardia; Vascular Resistance; Vasodilator Agents | 1974 |
Drugs and the heart. III. Calcium antagonists.
Topics: Angina Pectoris; Aniline Compounds; Arrhythmias, Cardiac; Calcium; Cardiomegaly; Diuretics; Heart Diseases; Heart Failure; Humans; Hypertension; Indapamide; Nifedipine; Perhexiline; Piperidines; Pyridines; Verapamil | 1980 |
A rapid method for the determination of perhexiline in serum using gas-liquid chromatography.
Topics: Adrenergic beta-Antagonists; Anti-Arrhythmia Agents; Chromatography, Gas; Drug Stability; Humans; Hydrogen-Ion Concentration; Perhexiline; Piperidines; Time Factors | 1980 |
Perhexiline maleate-induced lipidosis in cultured human fibroblasts: cell kinetics, ultrastructural and biochemical studies.
Topics: Cell Division; Cell Survival; Cells, Cultured; Cholesterol; Fibroblasts; Gangliosides; Humans; Kinetics; Lipidoses; Microscopy, Electron; Perhexiline; Phospholipids; Piperidines | 1980 |
Effects of perhexiline on myocardial phosphorylase activity, myocardial catecholamine content and heart rate.
Topics: Animals; Catecholamines; Heart Rate; Isoproterenol; Male; Myocardium; Norepinephrine; Perhexiline; Phosphorylase Kinase; Piperidines; Propranolol; Rats | 1981 |
Adverse effects of perhexiline.
Topics: Adult; Aged; Angina Pectoris; Female; Humans; Liver Cirrhosis; Male; Perhexiline; Peripheral Nervous System Diseases; Piperidines | 1982 |
Perhexiline hepatitis and HLA-B8.
Topics: Angina Pectoris; Chemical and Drug Induced Liver Injury; Diagnosis, Differential; Female; Genes; Hepatitis, Alcoholic; HLA Antigens; HLA-B Antigens; Humans; Middle Aged; Perhexiline; Piperidines | 1982 |
Synthesis and cardiovascular activity of a new series of cyclohexylaralkylamine derivatives related to perhexiline.
Topics: Adrenergic alpha-Antagonists; Animals; Calcium Channel Blockers; Cardiovascular Agents; Chemical Phenomena; Chemistry; Coronary Circulation; Dogs; Female; Male; Perhexiline; Piperidines; Rats; Swine | 1982 |
Antianginal efficacy of perhexiline maleate in patients refractory to beta-adrenoreceptor blockade.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Angina Pectoris; Double-Blind Method; Drug Resistance; Humans; Male; Middle Aged; Perhexiline; Piperidines | 1983 |
Peripheral neuropathy due to perhexilene maleate.
Topics: Aged; Female; Humans; Male; Middle Aged; Perhexiline; Peripheral Nerves; Peripheral Nervous System Diseases; Piperidines | 1980 |
Perhexiline maleate as a cause of reversible parkinsonism and peripheral neuropathy.
Topics: Aged; Angina Pectoris; Female; Humans; Parkinson Disease, Secondary; Perhexiline; Peripheral Nervous System Diseases; Piperidines | 1981 |
Effects of Pexid on liver cell cultures. Ultrastructural and histoenzymological studies.
Topics: Cells, Cultured; Gangliosides; Glycogen; Humans; Inclusion Bodies; Lipid Metabolism; Liver; Microscopy, Electron; Perhexiline; Piperidines | 1981 |
Impaired oxidation of debrisoquine in patients with perhexiline neuropathy.
Topics: Adult; Aged; Alcohol Drinking; Angina Pectoris; Debrisoquin; Female; Humans; Isoquinolines; Liver Function Tests; Male; Middle Aged; Oxidation-Reduction; Perhexiline; Peripheral Nervous System Diseases; Piperidines; Smoking | 1982 |
Perhexiline maleate induced lipidosis in human peripheral nerve and tissue culture: ultrastructural and biochemical changes.
Topics: Cells, Cultured; Fibroblasts; Humans; Lipidoses; Perhexiline; Peripheral Nerves; Peripheral Nervous System Diseases; Piperidines | 1981 |
Prediction of subclinical perhexiline neuropathy in a patient with inborn error of debrisoquine hydroxylation.
Topics: Angina Pectoris; Debrisoquin; Electromyography; Humans; Hydroxylation; Isoquinolines; Male; Middle Aged; Perhexiline; Peripheral Nervous System Diseases; Phenotype; Piperidines; Polymorphism, Genetic | 1983 |
[Study of thesaurismosis induced by perhexiline maleate. Confirmation of experimental data].
Topics: Cerebellar Ataxia; Female; Humans; Lipidoses; Middle Aged; Neuromuscular Diseases; Perhexiline; Peripheral Nerves; Peripheral Nervous System Diseases; Piperidines; Schwann Cells | 1983 |
Cirrhosis of the liver following therapy with perhexiline maleate.
Topics: Humans; Liver; Liver Cirrhosis; Male; Middle Aged; Perhexiline; Piperidines | 1983 |
Perhexiline and liver cirrhosis.
Topics: Dose-Response Relationship, Drug; Humans; Kinetics; Liver Cirrhosis; Perhexiline; Piperidines | 1983 |
Ultrastructural alterations in peripheral nerve trunks of rats subchronically treated with chlorphentermine or perhexiline.
Topics: Animals; Chlorphentermine; Female; Lipidoses; Male; Perhexiline; Peripheral Nerves; Phentermine; Piperidines; Rats; Rats, Inbred Strains; Schwann Cells | 1983 |
Effects of perhexiline on contractile response of rabbit aorta to norepinephrine and potassium.
Topics: Animals; Aorta, Thoracic; Drug Interactions; In Vitro Techniques; Muscle Contraction; Muscle, Smooth, Vascular; Nitroglycerin; Norepinephrine; Perhexiline; Piperidines; Potassium; Rabbits; Verapamil | 1980 |
Study of reasons for cessation of therapy with perhexiline maleate, sodium valproate and labetalol in the intensified adverse reaction reporting scheme.
Topics: Data Collection; Ethanolamines; Humans; Labetalol; Perhexiline; Piperidines; Surveys and Questionnaires; Valproic Acid | 1981 |
Effect of an antianginal drug, perhexiline, on myocardial oxygen consumption in anesthetized open-chest dogs compared with verapamil and glyceryl trinitrate.
Topics: Animals; Blood Pressure; Cardiac Surgical Procedures; Coronary Circulation; Dogs; Dose-Response Relationship, Drug; Heart Rate; Heart Ventricles; Myocardium; Nitroglycerin; Oxygen Consumption; Perhexiline; Piperidines; Verapamil | 1982 |
[Calling into question medical responsibility in a death following prolonged treatment with perhexiline maleate].
Topics: France; Humans; Liver Cirrhosis; Long-Term Care; Male; Malpractice; Middle Aged; Perhexiline; Piperidines | 1982 |
Perhexiline: good for refractory angina but take care!
Topics: Angina Pectoris; Humans; Perhexiline; Piperidines; Premedication | 1983 |
A simple and sensitive method for the determination of perhexiline in plasma using gas-liquid chromatography with nitrogen-phosphorus detection.
Topics: Chromatography, Gas; Humans; Nitrogen; Perhexiline; Phosphorus; Piperidines | 1983 |
Perhexiline maleate induced cirrhosis.
Topics: Aged; Angina Pectoris; Female; Humans; Liver; Liver Cirrhosis; Perhexiline; Piperidines | 1983 |
Unstable angina and perhexilene maleate.
Topics: Angina Pectoris; Humans; Perhexiline; Piperidines | 1981 |
Comparative effects of amiodarone, bepridil and perhexiline on coronary venous flow and several cardiovascular parameters.
Topics: Amines; Amiodarone; Animals; Benzofurans; Benzylamines; Bepridil; Coronary Circulation; Denervation; Dogs; Female; Heart; Heart Rate; Hemodynamics; Male; Oxygen Consumption; Perhexiline; Piperidines; Pyrrolidines; Time Factors | 1980 |
Liver disease induced by perhexiline maleate.
Topics: Chemical and Drug Induced Liver Injury; Perhexiline; Piperidines | 1982 |
Papilledema without peripheral neuropathy in a patient taking perhexiline maleate.
Topics: Adult; Angina Pectoris; Fluorescein Angiography; Humans; Male; Papilledema; Perhexiline; Piperidines; Visual Fields | 1982 |
Changes in the lysosomes and mitochondria isolated from the liver, kidney and heart of rats treated with perhexiline maleate.
Topics: Acetylglucosaminidase; Animals; Heart; In Vitro Techniques; Kidney; Liver; Lysosomes; Male; Mitochondria; Mitochondria, Heart; Mitochondria, Liver; Perhexiline; Piperidines; Rats; Rats, Inbred Strains | 1982 |
Perhexiline maleate toxicity on human liver cell lines.
Topics: Adult; Cell Line; Cell Survival; Female; Humans; Infant, Newborn; Liver; Lysosomes; Perhexiline; Piperidines; Pregnancy | 1980 |
[Comparative hepatic toxicity of perhexiline maleate and griseofulvin in mice].
Topics: Animals; Chemical and Drug Induced Liver Injury; Griseofulvin; Liver; Male; Mice; Perhexiline; Piperidines; Time Factors | 1981 |
Effects of several lipidosis-inducing drugs upon the area postrema and adjacent medullary nuclei of adult rats. II. Axonal alternations.
Topics: Animals; Axons; Chloroquine; Chlorphentermine; Medulla Oblongata; Microscopy, Electron; Perhexiline; Piperidines; Quinacrine; Rats | 1981 |
Antiarrhythmic evaluation of verapamil, nifedipine, perhexiline and skf 525-A in four canine models of cardiac arrhythmias.
Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Blood Pressure; Calcium; Dogs; Female; Heart Rate; Lidocaine; Male; Myocardial Contraction; Nifedipine; Perhexiline; Piperidines; Proadifen; Pyridines; Verapamil | 1981 |
High-performance liquid chromatographic assay of perhexiline maleate in plasma.
Topics: Aged; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Half-Life; Humans; Perhexiline; Piperidines; Time Factors | 1981 |
Lipid and lysosomal enzymes in human fibroblasts cultured with perhexiline maleate.
Topics: Cells, Cultured; Cholesterol; Fibroblasts; Gangliosides; Humans; Lipid Metabolism; Lysosomes; Perhexiline; Phospholipids; Piperidines | 1981 |
Effect of perhexilene on 86Rb uptake in experimental myocardial infarction.
Topics: Animals; Biological Transport, Active; Disease Models, Animal; Female; Heart; Isoproterenol; Male; Myocardial Infarction; Myocardium; Perhexiline; Piperidines; Rats; Rats, Inbred Strains; Rubidium | 1981 |
Perhexiline and aphonia.
Topics: Aphonia; Humans; Male; Middle Aged; Perhexiline; Piperidines | 1981 |
Liver disease induced by perhexiline maleate.
Topics: Angina Pectoris; Chemical and Drug Induced Liver Injury; Humans; Liver; Liver Cirrhosis, Alcoholic; Liver Diseases; Male; Middle Aged; Osteoarthritis; Perhexiline; Piperidines; Postoperative Complications; Transaminases | 1981 |
Effects of perhexiline on hemodynamics in anesthetized open-chest dogs.
Topics: Anesthesia; Animals; Blood Circulation; Blood Flow Velocity; Blood Pressure; Cardiac Output; Dogs; Dose-Response Relationship, Drug; Female; Heart Rate; Hemodynamics; Male; Norepinephrine; Perhexiline; Phentolamine; Piperidines; Propranolol; Verapamil | 1981 |
[Clinical and hemodynamic effects of perhexiline maleate in healthy subjects (author's transl)].
Topics: Adult; Heart; Hemodynamics; Humans; Male; Organ Size; Perhexiline; Piperidines | 1980 |
[Polyneuritis after use of perhexiline maleate: quantimetric and ultrastructural study (author's transl)].
Topics: Humans; Male; Middle Aged; Perhexiline; Piperidines; Polyradiculoneuropathy; Wallerian Degeneration | 1980 |
Effect of perhexiline maleate on lipid metabolism in the rat. III. Liver gangliosides after administration of high doses of perhexiline maleate.
Topics: Animals; Gangliosides; Liver; Male; Perhexiline; Piperidines; Rats; Time Factors | 1980 |
Perhexiline maleate-associated hepatic injury prevalence and characteristics.
Topics: Adult; Aged; Angina Pectoris; Biopsy, Needle; Chemical and Drug Induced Liver Injury; Female; France; Hepatomegaly; Humans; Liver; Liver Function Tests; Male; Middle Aged; Perhexiline; Piperidines | 1980 |
Papilloedema and hepatic dysfunction apparently induced by perhexiline maleate (Pexid).
Topics: Angina Pectoris; Chemical and Drug Induced Liver Injury; Humans; Male; Middle Aged; Papilledema; Perhexiline; Piperidines | 1980 |
Toxic polyneuritis and toxic hepatitis related to long-term perhexiline maleate therapy.
Topics: Angina Pectoris; Chemical and Drug Induced Liver Injury; Humans; Male; Middle Aged; Perhexiline; Piperidines; Polyneuropathies; Time Factors | 1980 |
Effects of oral perhexiline on canine myocardial flow distribution.
Topics: Animals; Blood Pressure; Coronary Circulation; Dogs; Dose-Response Relationship, Drug; Heart Rate; Myocardial Infarction; Perhexiline; Piperidines | 1980 |
Hepatotoxicity following treatment with perhexiline maleate.
Topics: Aged; Angina Pectoris; Chemical and Drug Induced Liver Injury; Female; Humans; Male; Middle Aged; Perhexiline; Piperidines | 1980 |
Effect of perhexiline maleate on bile formation and liver disposition of sulfobromophthalein in the rat.
Topics: Animals; Bile; Bile Acids and Salts; Body Weight; Liver; Male; Perhexiline; Piperidines; Propylene Glycols; Rats; Sulfobromophthalein | 1980 |
Effects of several lipidosis-including drugs upon the area postrema and adjacent medullary nuclei of adult rats. I. Alterations is perikarya and dendrites.
Topics: Animals; Blood-Brain Barrier; Brain Diseases; Chloroquine; Chlorphentermine; Female; Lipidoses; Male; Medulla Oblongata; Microscopy, Electron; Perhexiline; Piperidines; Quinacrine; Rats; Time Factors | 1980 |
Inhibition of HERG channels stably expressed in a mammalian cell line by the antianginal agent perhexiline maleate.
Topics: Algorithms; Animals; Anti-Arrhythmia Agents; Cardiovascular Agents; Cation Transport Proteins; CHO Cells; Cricetinae; Electric Stimulation; Ether-A-Go-Go Potassium Channels; In Vitro Techniques; Membrane Potentials; Oocytes; Patch-Clamp Techniques; Perhexiline; Piperidines; Potassium Channels; Potassium Channels, Voltage-Gated; Pyridines; Xenopus laevis | 1999 |