perhexiline and dextromethorphan

perhexiline has been researched along with dextromethorphan in 4 studies

Research

Studies (4)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	1 (25.00)	18.2507
2000's	2 (50.00)	29.6817
2010's	1 (25.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Bleich, S; Gulbins, E; Kornhuber, J; Reichel, M; Terfloth, L; Tripal, P; Wiltfang, J	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Bochner, F; Kerry, NL; Mikus, G; Somogyi, AA	1
Coller, JK; Davies, BJ; Gillis, D; Horowitz, JD; James, HM; Morris, RG; Sallustio, BC; Somogyi, AA	1

Reviews

1 review(s) available for perhexiline and dextromethorphan

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016

Trials

1 trial(s) available for perhexiline and dextromethorphan

Article	Year
Clinical inhibition of CYP2D6-catalysed metabolism by the antianginal agent perhexiline. British journal of clinical pharmacology, 2004, Volume: 57, Issue:4 Topics: Aged; Angina Pectoris; Cardiovascular Agents; Cytochrome P-450 CYP2D6 Inhibitors; Dextromethorphan; Dextrorphan; Female; Humans; Male; Perhexiline	2004

Other Studies

2 other study(ies) available for perhexiline and dextromethorphan

Article	Year
Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model. Journal of medicinal chemistry, 2008, Jan-24, Volume: 51, Issue:2 Topics: Algorithms; Animals; Cell Line; Cell Line, Tumor; Chemical Phenomena; Chemistry, Physical; Enzyme Inhibitors; Humans; Hydrogen-Ion Concentration; Molecular Conformation; Quantitative Structure-Activity Relationship; Rats; Sphingomyelin Phosphodiesterase	2008
The role of CYP2D6 in primary and secondary oxidative metabolism of dextromethorphan: in vitro studies using human liver microsomes. British journal of clinical pharmacology, 1994, Volume: 38, Issue:3 Topics: Autoantibodies; Binding, Competitive; Cytochrome P-450 CYP2D6; Cytochrome P-450 Enzyme System; Dextromethorphan; Dextropropoxyphene; Dextrorphan; Humans; In Vitro Techniques; Methadone; Methylation; Microsomes, Liver; Mixed Function Oxygenases; Oxidation-Reduction; Perhexiline; Phenotype; Quinidine	1994

Article

Year

Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model.

Journal of medicinal chemistry, 2008, Jan-24, Volume: 51, Issue:2

Topics: Algorithms; Animals; Cell Line; Cell Line, Tumor; Chemical Phenomena; Chemistry, Physical; Enzyme Inhibitors; Humans; Hydrogen-Ion Concentration; Molecular Conformation; Quantitative Structure-Activity Relationship; Rats; Sphingomyelin Phosphodiesterase

2008

The role of CYP2D6 in primary and secondary oxidative metabolism of dextromethorphan: in vitro studies using human liver microsomes.

British journal of clinical pharmacology, 1994, Volume: 38, Issue:3

Topics: Autoantibodies; Binding, Competitive; Cytochrome P-450 CYP2D6; Cytochrome P-450 Enzyme System; Dextromethorphan; Dextropropoxyphene; Dextrorphan; Humans; In Vitro Techniques; Methadone; Methylation; Microsomes, Liver; Mixed Function Oxygenases; Oxidation-Reduction; Perhexiline; Phenotype; Quinidine

1994